| Ident. | Authors (with country if any) | Title |
|---|
| 000300 (2019) |
Zhen Guo [République populaire de Chine] ; Xiaowei Song [République populaire de Chine] ; Li-Min Zhao [République populaire de Chine] ; Ming Guan Piao [République populaire de Chine] ; Jishan Quan [République populaire de Chine] ; Hu-Ri Piao [République populaire de Chine] ; Cheng Hua Jin [République populaire de Chine] | Synthesis and biological evaluation of novel benzo[c][1,2,5]thiadiazol-5-yl and thieno[3,2-c]- pyridin-2-yl imidazole derivatives as ALK5 inhibitors. |
| 000D55 (2017) |
Cloé Comarmond [France] ; Marlène Garrido [France] ; Stanislas Pol [France] ; Anne-Claire Desbois [France] ; Myrto Costopoulos [France] ; Magali Le Garff-Tavernier [France] ; Si Nafa Si Ahmed [France] ; Laurent Alric [France] ; Hélène Fontaine [France] ; Bertrand Bellier [France] ; Anna Maciejewski [France] ; Michelle Rosenzwajg [France] ; David Klatzmann [France] ; Lucile Musset [France] ; Thierry Poynard [France] ; Patrice Cacoub [France] ; David Saadoun [France] | Direct-Acting Antiviral Therapy Restores Immune Tolerance to Patients With Hepatitis C Virus-Induced Cryoglobulinemia Vasculitis. |
| 000F03 (2016) |
Sixuan Qian [République populaire de Chine] ; Jianyong Li [République populaire de Chine] ; Ming Hong [République populaire de Chine] ; Yu Zhu [République populaire de Chine] ; Huihui Zhao [République populaire de Chine] ; Yue Xie [République populaire de Chine] ; Jiayu Huang [République populaire de Chine] ; Yun Lian [République populaire de Chine] ; Yanru Li [République populaire de Chine] ; Shuai Wang [République populaire de Chine] ; Jianping Mao [République populaire de Chine] ; Yaoyu Chen [République populaire de Chine] | TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemia. |
| 001084 (2016) |
Marla Weetall [États-Unis] ; Thomas Davis [États-Unis] ; Gary Elfring [États-Unis] ; Valerie Northcutt [États-Unis] ; Liangxian Cao [États-Unis] ; Young-Choon Moon [États-Unis] ; Peter Riebling [États-Unis] ; Mandar Dali [États-Unis] ; Samit Hirawat [États-Unis] ; John Babiak [États-Unis] ; Joseph Colacino [États-Unis] ; Neil Almstead [États-Unis] ; Robert Spiegel [États-Unis] ; Stuart W. Peltz [États-Unis] | Phase 1 Study of Safety, Tolerability, and Pharmacokinetics of PTC299, an Inhibitor of Stress-Regulated Protein Translation. |
| 001090 (2016) |
Wei Zhang ; Yuan Liu ; Yu Feng Li ; Yun Yue ; Xinghua Yang ; Lin Peng | Targeting of Survivin Pathways by YM155 Inhibits Cell Death and Invasion in Oral Squamous Cell Carcinoma Cells. |
| 001099 (2016) |
Deepak Bushan Raina [Suède] ; Hanna Isaksson [Suède] ; Arun Kumar Teotia [Inde] ; Lars Lidgren [Suède] ; Magnus T Gil [Suède] ; Ashok Kumar [Inde] | Biocomposite macroporous cryogels as potential carrier scaffolds for bone active agents augmenting bone regeneration. |
| 001235 (2016) |
Hsin-Lin Cheng [Taïwan] ; Chiao-Wen Lin [Taïwan] ; Jia-Sin Yang [Taïwan] ; Ming-Ju Hsieh [Taïwan] ; Shun-Fa Yang [Taïwan] ; Ko-Hsiu Lu [Taïwan] | Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways. |
| 001586 (2015) |
Caroline Wilson [Royaume-Uni] ; Penelope Ottewell [Royaume-Uni] ; Robert E. Coleman [Royaume-Uni] ; Ingunn Holen [Royaume-Uni] | The differential anti-tumour effects of zoledronic acid in breast cancer - evidence for a role of the activin signaling pathway. |
| 001759 (2015) |
Yu Jiao [République populaire de Chine] ; Bo-Tao Xin [Pays-Bas] ; Yanmin Zhang [République populaire de Chine] ; Jianbing Wu [République populaire de Chine] ; Xiaolin Lu [République populaire de Chine] ; Ying Zheng [République populaire de Chine] ; Weifang Tang [République populaire de Chine] ; Xiang Zhou [République populaire de Chine] | Design, synthesis and evaluation of novel 2-(1H-imidazol-2-yl) pyridine Sorafenib derivatives as potential BRAF inhibitors and anti-tumor agents. |
| 001822 (2014) |
E E W. Cohen [États-Unis] ; M. Tortorici ; S. Kim ; A. Ingrosso ; Y K Pithavala ; P. Bycott | A Phase II trial of axitinib in patients with various histologic subtypes of advanced thyroid cancer: long-term outcomes and pharmacokinetic/pharmacodynamic analyses. |
| 001874 (2014) |
Graziela N. Hagihara [Brésil] ; Nubia S. Lobato [Brésil] ; Fernando P. Filgueira [Brésil] ; Eliana H. Akamine [Brésil] ; Danielle S. Aragão [Brésil] ; Dulce E. Casarini [Brésil] ; Maria Helena C. Carvalho [Brésil] ; Zuleica B. Fortes [Brésil] | Upregulation of ERK1/2-eNOS via AT2 receptors decreases the contractile response to angiotensin II in resistance mesenteric arteries from obese rats. |
| 001B13 (2014) |
Yeon-Hui Jeong [Corée du Sud] ; Yongju Kim [Corée du Sud] ; Heebum Song [Corée du Sud] ; Young Sun Chung [Corée du Sud] ; Seung Bum Park [Corée du Sud] ; Hee-Sun Kim [Corée du Sud] | Anti-inflammatory effects of α-galactosylceramide analogs in activated microglia: involvement of the p38 MAPK signaling pathway. |
| 001B75 (2014) |
R. Chavez-Valdez [États-Unis] ; L J Martin [États-Unis] ; S. Razdan [États-Unis] ; E B Gauda [États-Unis] ; F J Northington [États-Unis] | Sexual dimorphism in BDNF signaling after neonatal hypoxia-ischemia and treatment with necrostatin-1. |
| 001C41 (2013) |
F. Bruzzese [Italie] ; B. Pucci ; M R Milone ; C. Ciardiello ; R. Franco ; M I Chianese ; M. Rocco ; E. Di Gennaro ; A. Leone ; A. Luciano ; C. Arra ; D. Santini ; M. Caraglia ; A. Budillon | Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways. |
| 001D24 (2013) |
M G Rodrigues-Machado [Brésil] ; G S Magalhães ; J A Cardoso ; L M Kangussu ; A. Murari ; M V Caliari ; M L Oliveira ; D C Cara ; M L M. Noviello ; F D Marques ; J M Pereira ; R Q Lautner ; R A S. Santos ; M J Campagnole-Santos | AVE 0991, a non-peptide mimic of angiotensin-(1-7) effects, attenuates pulmonary remodelling in a model of chronic asthma. |
| 001F03 (2012) |
Yan-Fang Tao [République populaire de Chine] ; Jun Lu ; Xiao-Juan Du ; Li-Chao Sun ; Xuan Zhao ; Liang Peng ; Lan Cao ; Pei-Fang Xiao ; Li Pang ; Dong Wu ; Na Wang ; Xing Feng ; Yan-Hong Li ; Jian Ni ; Jian Wang ; Jian Pan | Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells. |
| 001F10 (2013) |
F. Gomez-Veiga [Espagne] ; J. Ponce-Reixa ; S. Martinez-Breijo ; J. Planas ; J. Morote | Advances in prevention and treatment of bone metastases in prostate cancer. Role of RANK/RANKL inhibition. |
| 002023 (2012) |
S. Vadhan-Raj [États-Unis] ; R. Von Moos [Suisse] ; L J Fallowfield [Royaume-Uni] ; D L Patrick [États-Unis] ; F. Goldwasser [France] ; C S Cleeland [États-Unis] ; D H Henry [États-Unis] ; S. Novello [Italie] ; V. Hungria [Brésil] ; Y. Qian [États-Unis] ; A. Feng [États-Unis] ; H. Yeh [États-Unis] ; K. Chung [États-Unis] | Clinical benefit in patients with metastatic bone disease: results of a phase 3 study of denosumab versus zoledronic acid. |
| 002231 (2012) |
Xiaoliang Chen [République populaire de Chine] ; Yang Li ; Morley Hollenberg ; Chris R. Triggle ; Hong Ding | The contribution of d-tubocurarine-sensitive and apamin-sensitive K-channels to EDHF-mediated relaxation of mesenteric arteries from eNOS-/- mice. |
| 002514 (2011) |
Qun Li [États-Unis] ; Chaoyu Chen ; Amit Kapadia ; Qiong Zhou ; Mary Kay Harper ; Jerome Schaack ; Daniel V. Labarbera | 3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen. |
| 002603 (2011) |
Keith Thompson [Royaume-Uni] ; Fran Keech ; David J. Mclernon ; Kumar Vinod ; Robin J. May ; William G. Simpson ; Michael J. Rogers ; David M. Reid | Fluvastatin does not prevent the acute-phase response to intravenous zoledronic acid in post-menopausal women. |
