Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.
Identifieur interne : 003460 ( PubMed/Curation ); précédent : 003459; suivant : 003461Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.
Auteurs : Lauren M. Mcgrath [États-Unis] ; Dongmei Yu [États-Unis] ; Christian Marshall ; Lea K. Davis ; Bhooma Thiruvahindrapuram ; Bingbin Li ; Carolina Cappi ; Gloria Gerber [États-Unis] ; Aaron Wolf [États-Unis] ; Frederick A. Schroeder [États-Unis] ; Lisa Osiecki [États-Unis] ; Colm O'Dushlaine [États-Unis] ; Andrew Kirby [États-Unis] ; Cornelia Illmann [États-Unis] ; Stephen Haddad [États-Unis] ; Patience Gallagher [États-Unis] ; Jesen A. Fagerness [États-Unis] ; Cathy L. Barr ; Laura Bellodi [Italie] ; Fortu Benarroch ; O Joseph Bienvenu [États-Unis] ; Donald W. Black ; Michael H. Bloch [États-Unis] ; Ruth D. Bruun [États-Unis] ; Cathy L. Budman [États-Unis] ; Beatriz Camarena [Mexique] ; Danielle C. Cath [Pays-Bas] ; Maria C. Cavallini [Italie] ; Sylvain Chouinard ; Vladimir Coric [États-Unis] ; Bernadette Cullen [États-Unis] ; Richard Delorme [France] ; Damiaan Denys [Pays-Bas] ; Eske M. Derks [Pays-Bas] ; Yves Dion ; Maria C. Rosário ; Valsama Eapen [Australie] ; Patrick Evans ; Peter Falkai ; Thomas V. Fernandez [États-Unis] ; Helena Garrido [Costa Rica] ; Daniel Geller [États-Unis] ; Hans J. Grabe [Allemagne] ; Marco A. Grados [États-Unis] ; Benjamin D. Greenberg [États-Unis] ; Varda Gross-Tsur ; Edna Grünblatt ; Gary A. Heiman [États-Unis] ; Sian M J. Hemmings [Afrique du Sud] ; Luis D. Herrera [Costa Rica] ; Ana G. Hounie ; Joseph Jankovic [États-Unis] ; James L. Kennedy ; Robert A. King [États-Unis] ; Roger Kurlan [États-Unis] ; Nuria Lanzagorta ; Marion Leboyer [France] ; James F. Leckman [États-Unis] ; Leonhard Lennertz [Allemagne] ; Christine Lochner [Afrique du Sud] ; Thomas L. Lowe ; Gholson J. Lyon [États-Unis] ; Fabio Macciardi ; Wolfgang Maier [Allemagne] ; James T. Mccracken ; William Mcmahon ; Dennis L. Murphy [États-Unis] ; Allan L. Naarden ; Benjamin M. Neale [États-Unis] ; Erika Nurmi ; Andrew J. Pakstis [États-Unis] ; Michele T. Pato [États-Unis] ; Carlos N. Pato [États-Unis] ; John Piacentini ; Christopher Pittenger [États-Unis] ; Yehuda Pollak ; Victor I. Reus ; Margaret A. Richter ; Mark Riddle [États-Unis] ; Mary M. Robertson ; David Rosenberg ; Guy A. Rouleau ; Stephan Ruhrmann [Allemagne] ; Aline S. Sampaio [Brésil] ; Jack Samuels [États-Unis] ; Paul Sandor ; Brooke Sheppard ; Harvey S. Singer [États-Unis] ; Jan H. Smit [Pays-Bas] ; Dan J. Stein [Afrique du Sud] ; Jay A. Tischfield [États-Unis] ; Homero Vallada ; Jeremy Veenstra-Vanderweele [États-Unis] ; Susanne Walitza ; Ying Wang [États-Unis] ; Jens R. Wendland [États-Unis] ; Yin Yao Shugart [États-Unis] ; Euripedes C. Miguel ; Humberto Nicolini ; Ben A. Oostra [Pays-Bas] ; Rainald Moessner [Allemagne] ; Michael Wagner [Allemagne] ; Andres Ruiz-Linares ; Peter Heutink ; Gerald Nestadt [États-Unis] ; Nelson Freimer ; Tracey Petryshen [États-Unis] ; Danielle Posthuma [Pays-Bas] ; Michael A. Jenike [États-Unis] ; Nancy J. Cox ; Gregory L. Hanna [États-Unis] ; Helena Brentani ; Stephen W. Scherer ; Paul D. Arnold ; S Evelyn Stewart ; Carol A. Mathews ; James A. Knowles [États-Unis] ; Edwin H. Cook ; David L. Pauls [États-Unis] ; Kai Wang [États-Unis] ; Jeremiah M. Scharf [États-Unis]Source :
- Journal of the American Academy of Child and Adolescent Psychiatry [ 1527-5418 ] ; 2014.
Descripteurs français
- KwdFr :
- Adolescent, Diagnostic and stastistical manual of mental disorders (USA), Femelle, Humains, Mâle, Polymorphisme de nucléotide simple, Prédisposition génétique à une maladie, Syndrome de Tourette (diagnostic), Syndrome de Tourette (génétique), Trouble obsessionnel compulsif (diagnostic), Trouble obsessionnel compulsif (génétique), Variations de nombre de copies de segment d'ADN, Étude d'association pangénomique.
- MESH :
- diagnostic : Syndrome de Tourette, Trouble obsessionnel compulsif.
- génétique : Syndrome de Tourette, Trouble obsessionnel compulsif.
- Adolescent, Diagnostic and stastistical manual of mental disorders (USA), Femelle, Humains, Mâle, Polymorphisme de nucléotide simple, Prédisposition génétique à une maladie, Variations de nombre de copies de segment d'ADN, Étude d'association pangénomique.
English descriptors
- KwdEn :
- Adolescent, DNA Copy Number Variations, Diagnostic and Statistical Manual of Mental Disorders, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Obsessive-Compulsive Disorder (diagnosis), Obsessive-Compulsive Disorder (genetics), Polymorphism, Single Nucleotide, Tourette Syndrome (diagnosis), Tourette Syndrome (genetics).
- MESH :
- diagnosis : Obsessive-Compulsive Disorder, Tourette Syndrome.
- genetics : Obsessive-Compulsive Disorder, Tourette Syndrome.
- Adolescent, DNA Copy Number Variations, Diagnostic and Statistical Manual of Mental Disorders, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Polymorphism, Single Nucleotide.
Abstract
Obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) are heritable neurodevelopmental disorders with a partially shared genetic etiology. This study represents the first genome-wide investigation of large (>500 kb), rare (<1%) copy number variants (CNVs) in OCD and the largest genome-wide CNV analysis in TS to date.
DOI: 10.1016/j.jaac.2014.04.022
PubMed: 25062598
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Christian Marshall<affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Toronto Western Research Institute, University Health Network, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Hadassah-Hebrew University Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Iowa College of Medicine, Iowa City.</nlm:affiliation><wicri:noCountry code="subField">Iowa City</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Montreal.</nlm:affiliation><wicri:noCountry code="no comma">University of Montreal.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Montreal.</nlm:affiliation><wicri:noCountry code="no comma">University of Montreal.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Federal University of São Paulo.</nlm:affiliation><wicri:noCountry code="no comma">Federal University of São Paulo.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Munich.</nlm:affiliation><wicri:noCountry code="no comma">University of Munich.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Shaare Zedek Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Zurich.</nlm:affiliation><wicri:noCountry code="no comma">University of Zurich.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Federal University of São Paulo.</nlm:affiliation><wicri:noCountry code="no comma">Federal University of São Paulo.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Centre for Addiction and Mental Health, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Carracci Medical Group, Mexico City.</nlm:affiliation><wicri:noCountry code="subField">Mexico City</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California, Irvine.</nlm:affiliation><wicri:noCountry code="subField">Irvine</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Utah, Salt Lake City.</nlm:affiliation><wicri:noCountry code="subField">Salt Lake City</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Medical City Dallas Hospital.</nlm:affiliation><wicri:noCountry code="no comma">Medical City Dallas Hospital.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Shaare Zedek Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Sunnybrook Health Sciences Centre, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University College London.</nlm:affiliation><wicri:noCountry code="no comma">University College London.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Wayne State University and Detroit Medical Center, Detroit.</nlm:affiliation><wicri:noCountry code="subField">Detroit</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Montreal Neurological Institute.</nlm:affiliation><wicri:noCountry code="no comma">Montreal Neurological Institute.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Toronto Western Research Institute, University Health Network, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Zurich; University of Würzburg.</nlm:affiliation><wicri:noCountry code="no comma">University of Zurich; University of Würzburg.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Carracci Medical Group, Mexico City.</nlm:affiliation><wicri:noCountry code="subField">Mexico City</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University College London.</nlm:affiliation><wicri:noCountry code="no comma">University College London.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>German Center for Neurodegenerative Diseases, Bonn and VU Medical Center Amsterdam.</nlm:affiliation><wicri:noCountry code="subField">Bonn and VU Medical Center Amsterdam</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine; Semel Institute for Neuroscience and Human Behavior, UCLA.</nlm:affiliation><wicri:noCountry code="subField">UCLA</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Massachusetts General Hospital, Boston; University of British Columbia, Vancouver.</nlm:affiliation><wicri:noCountry code="subField">Vancouver</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>University of Illinois at Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Illinois at Chicago.</wicri:noCountry></affiliation>Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.</title><author><name sortKey="Mcgrath, Lauren M" sort="Mcgrath, Lauren M" uniqKey="Mcgrath L" first="Lauren M" last="Mcgrath">Lauren M. Mcgrath</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; American University, Washington, DC; Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; American University, Washington, DC; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Yu, Dongmei" sort="Yu, Dongmei" uniqKey="Yu D" first="Dongmei" last="Yu">Dongmei Yu</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Marshall, Christian" sort="Marshall, Christian" uniqKey="Marshall C" first="Christian" last="Marshall">Christian Marshall</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Davis, Lea K" sort="Davis, Lea K" uniqKey="Davis L" first="Lea K" last="Davis">Lea K. Davis</name><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation></author><author><name sortKey="Thiruvahindrapuram, Bhooma" sort="Thiruvahindrapuram, Bhooma" uniqKey="Thiruvahindrapuram B" first="Bhooma" last="Thiruvahindrapuram">Bhooma Thiruvahindrapuram</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Li, Bingbin" sort="Li, Bingbin" uniqKey="Li B" first="Bingbin" last="Li">Bingbin Li</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Cappi, Carolina" sort="Cappi, Carolina" uniqKey="Cappi C" first="Carolina" last="Cappi">Carolina Cappi</name><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation></author><author><name sortKey="Gerber, Gloria" sort="Gerber, Gloria" uniqKey="Gerber G" first="Gloria" last="Gerber">Gloria Gerber</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Wolf, Aaron" sort="Wolf, Aaron" uniqKey="Wolf A" first="Aaron" last="Wolf">Aaron Wolf</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Schroeder, Frederick A" sort="Schroeder, Frederick A" uniqKey="Schroeder F" first="Frederick A" last="Schroeder">Frederick A. Schroeder</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Osiecki, Lisa" sort="Osiecki, Lisa" uniqKey="Osiecki L" first="Lisa" last="Osiecki">Lisa Osiecki</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="O Dushlaine, Colm" sort="O Dushlaine, Colm" uniqKey="O Dushlaine C" first="Colm" last="O'Dushlaine">Colm O'Dushlaine</name><affiliation wicri:level="3"><nlm:affiliation>Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Kirby, Andrew" sort="Kirby, Andrew" uniqKey="Kirby A" first="Andrew" last="Kirby">Andrew Kirby</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Illmann, Cornelia" sort="Illmann, Cornelia" uniqKey="Illmann C" first="Cornelia" last="Illmann">Cornelia Illmann</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Haddad, Stephen" sort="Haddad, Stephen" uniqKey="Haddad S" first="Stephen" last="Haddad">Stephen Haddad</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Gallagher, Patience" sort="Gallagher, Patience" uniqKey="Gallagher P" first="Patience" last="Gallagher">Patience Gallagher</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Fagerness, Jesen A" sort="Fagerness, Jesen A" uniqKey="Fagerness J" first="Jesen A" last="Fagerness">Jesen A. Fagerness</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Barr, Cathy L" sort="Barr, Cathy L" uniqKey="Barr C" first="Cathy L" last="Barr">Cathy L. Barr</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Toronto Western Research Institute, University Health Network, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Bellodi, Laura" sort="Bellodi, Laura" uniqKey="Bellodi L" first="Laura" last="Bellodi">Laura Bellodi</name><affiliation wicri:level="3"><nlm:affiliation>Università Vita-Salute San Raffaele, Milan.</nlm:affiliation><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName><wicri:orgArea>Università Vita-Salute San Raffaele</wicri:orgArea></affiliation></author><author><name sortKey="Benarroch, Fortu" sort="Benarroch, Fortu" uniqKey="Benarroch F" first="Fortu" last="Benarroch">Fortu Benarroch</name><affiliation><nlm:affiliation>Hadassah-Hebrew University Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation></author><author><name sortKey="Bienvenu, O Joseph" sort="Bienvenu, O Joseph" uniqKey="Bienvenu O" first="O Joseph" last="Bienvenu">O Joseph Bienvenu</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Black, Donald W" sort="Black, Donald W" uniqKey="Black D" first="Donald W" last="Black">Donald W. Black</name><affiliation><nlm:affiliation>University of Iowa College of Medicine, Iowa City.</nlm:affiliation><wicri:noCountry code="subField">Iowa City</wicri:noCountry></affiliation></author><author><name sortKey="Bloch, Michael H" sort="Bloch, Michael H" uniqKey="Bloch M" first="Michael H" last="Bloch">Michael H. Bloch</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Bruun, Ruth D" sort="Bruun, Ruth D" uniqKey="Bruun R" first="Ruth D" last="Bruun">Ruth D. Bruun</name><affiliation wicri:level="2"><nlm:affiliation>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; New York University Medical Center, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; New York University Medical Center</wicri:cityArea></affiliation></author><author><name sortKey="Budman, Cathy L" sort="Budman, Cathy L" uniqKey="Budman C" first="Cathy L" last="Budman">Cathy L. Budman</name><affiliation wicri:level="2"><nlm:affiliation>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; Hofstra University School of Medicine, Hempstead, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; Hofstra University School of Medicine, Hempstead</wicri:cityArea></affiliation></author><author><name sortKey="Camarena, Beatriz" sort="Camarena, Beatriz" uniqKey="Camarena B" first="Beatriz" last="Camarena">Beatriz Camarena</name><affiliation wicri:level="1"><nlm:affiliation>Instituto Nacional de Psiquiatría Ramon de la Fuente Muñiz, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Instituto Nacional de Psiquiatría Ramon de la Fuente Muñiz</wicri:regionArea></affiliation></author><author><name sortKey="Cath, Danielle C" sort="Cath, Danielle C" uniqKey="Cath D" first="Danielle C" last="Cath">Danielle C. Cath</name><affiliation wicri:level="3"><nlm:affiliation>Utrecht University and VU Medical Center, Amsterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName><wicri:orgArea>Utrecht University and VU Medical Center</wicri:orgArea></affiliation></author><author><name sortKey="Cavallini, Maria C" sort="Cavallini, Maria C" uniqKey="Cavallini M" first="Maria C" last="Cavallini">Maria C. Cavallini</name><affiliation wicri:level="3"><nlm:affiliation>Ospedale San Raffaele, Milan.</nlm:affiliation><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName><wicri:orgArea>Ospedale San Raffaele</wicri:orgArea></affiliation></author><author><name sortKey="Chouinard, Sylvain" sort="Chouinard, Sylvain" uniqKey="Chouinard S" first="Sylvain" last="Chouinard">Sylvain Chouinard</name><affiliation><nlm:affiliation>University of Montreal.</nlm:affiliation><wicri:noCountry code="no comma">University of Montreal.</wicri:noCountry></affiliation></author><author><name sortKey="Coric, Vladimir" sort="Coric, Vladimir" uniqKey="Coric V" first="Vladimir" last="Coric">Vladimir Coric</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Cullen, Bernadette" sort="Cullen, Bernadette" uniqKey="Cullen B" first="Bernadette" last="Cullen">Bernadette Cullen</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Delorme, Richard" sort="Delorme, Richard" uniqKey="Delorme R" first="Richard" last="Delorme">Richard Delorme</name><affiliation wicri:level="3"><nlm:affiliation>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; Institut Pasteur, Paris.</nlm:affiliation><country>France</country><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName><wicri:orgArea>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; Institut Pasteur</wicri:orgArea></affiliation></author><author><name sortKey="Denys, Damiaan" sort="Denys, Damiaan" uniqKey="Denys D" first="Damiaan" last="Denys">Damiaan Denys</name><affiliation wicri:level="3"><nlm:affiliation>Netherlands Institute for Neuroscience, Amsterdam; Academic Medical Center, Amsterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName><wicri:orgArea>Netherlands Institute for Neuroscience, Amsterdam; Academic Medical Center</wicri:orgArea></affiliation></author><author><name sortKey="Derks, Eske M" sort="Derks, Eske M" uniqKey="Derks E" first="Eske M" last="Derks">Eske M. Derks</name><affiliation wicri:level="3"><nlm:affiliation>Academic Medical Center, Amsterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName><wicri:orgArea>Academic Medical Center</wicri:orgArea></affiliation></author><author><name sortKey="Dion, Yves" sort="Dion, Yves" uniqKey="Dion Y" first="Yves" last="Dion">Yves Dion</name><affiliation><nlm:affiliation>University of Montreal.</nlm:affiliation><wicri:noCountry code="no comma">University of Montreal.</wicri:noCountry></affiliation></author><author><name sortKey="Rosario, Maria C" sort="Rosario, Maria C" uniqKey="Rosario M" first="Maria C" last="Rosário">Maria C. Rosário</name><affiliation><nlm:affiliation>Federal University of São Paulo.</nlm:affiliation><wicri:noCountry code="no comma">Federal University of São Paulo.</wicri:noCountry></affiliation></author><author><name sortKey="Eapen, Valsama" sort="Eapen, Valsama" uniqKey="Eapen V" first="Valsama" last="Eapen">Valsama Eapen</name><affiliation wicri:level="1"><nlm:affiliation>University of New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Evans, Patrick" sort="Evans, Patrick" uniqKey="Evans P" first="Patrick" last="Evans">Patrick Evans</name><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation></author><author><name sortKey="Falkai, Peter" sort="Falkai, Peter" uniqKey="Falkai P" first="Peter" last="Falkai">Peter Falkai</name><affiliation><nlm:affiliation>University of Munich.</nlm:affiliation><wicri:noCountry code="no comma">University of Munich.</wicri:noCountry></affiliation></author><author><name sortKey="Fernandez, Thomas V" sort="Fernandez, Thomas V" uniqKey="Fernandez T" first="Thomas V" last="Fernandez">Thomas V. Fernandez</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Garrido, Helena" sort="Garrido, Helena" uniqKey="Garrido H" first="Helena" last="Garrido">Helena Garrido</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Nacional de Niños, San Jose, Costa Rica; Clinica Herrera Amighetti, Avenida Escazú, San José, Costa Rica.</nlm:affiliation><country xml:lang="fr">Costa Rica</country><wicri:regionArea>Hospital Nacional de Niños, San Jose, Costa Rica; Clinica Herrera Amighetti, Avenida Escazú, San José</wicri:regionArea></affiliation></author><author><name sortKey="Geller, Daniel" sort="Geller, Daniel" uniqKey="Geller D" first="Daniel" last="Geller">Daniel Geller</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Grabe, Hans J" sort="Grabe, Hans J" uniqKey="Grabe H" first="Hans J" last="Grabe">Hans J. Grabe</name><affiliation wicri:level="1"><nlm:affiliation>University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Medicine Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Grados, Marco A" sort="Grados, Marco A" uniqKey="Grados M" first="Marco A" last="Grados">Marco A. Grados</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Greenberg, Benjamin D" sort="Greenberg, Benjamin D" uniqKey="Greenberg B" first="Benjamin D" last="Greenberg">Benjamin D. Greenberg</name><affiliation wicri:level="2"><nlm:affiliation>Brown Medical School, Providence, RI.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Rhode Island</region></placeName><wicri:cityArea>Brown Medical School, Providence</wicri:cityArea></affiliation></author><author><name sortKey="Gross Tsur, Varda" sort="Gross Tsur, Varda" uniqKey="Gross Tsur V" first="Varda" last="Gross-Tsur">Varda Gross-Tsur</name><affiliation><nlm:affiliation>Shaare Zedek Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation></author><author><name sortKey="Grunblatt, Edna" sort="Grunblatt, Edna" uniqKey="Grunblatt E" first="Edna" last="Grünblatt">Edna Grünblatt</name><affiliation><nlm:affiliation>University of Zurich.</nlm:affiliation><wicri:noCountry code="no comma">University of Zurich.</wicri:noCountry></affiliation></author><author><name sortKey="Heiman, Gary A" sort="Heiman, Gary A" uniqKey="Heiman G" first="Gary A" last="Heiman">Gary A. Heiman</name><affiliation wicri:level="2"><nlm:affiliation>Rutgers University, Piscataway Township, NJ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Rutgers University, Piscataway Township</wicri:cityArea></affiliation></author><author><name sortKey="Hemmings, Sian M J" sort="Hemmings, Sian M J" uniqKey="Hemmings S" first="Sian M J" last="Hemmings">Sian M J. Hemmings</name><affiliation wicri:level="1"><nlm:affiliation>University of Stellenbosch, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of Stellenbosch</wicri:regionArea></affiliation></author><author><name sortKey="Herrera, Luis D" sort="Herrera, Luis D" uniqKey="Herrera L" first="Luis D" last="Herrera">Luis D. Herrera</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Nacional de Niños, San Jose, Costa Rica.</nlm:affiliation><country xml:lang="fr">Costa Rica</country><wicri:regionArea>Hospital Nacional de Niños, San Jose</wicri:regionArea></affiliation></author><author><name sortKey="Hounie, Ana G" sort="Hounie, Ana G" uniqKey="Hounie A" first="Ana G" last="Hounie">Ana G. Hounie</name><affiliation><nlm:affiliation>Federal University of São Paulo.</nlm:affiliation><wicri:noCountry code="no comma">Federal University of São Paulo.</wicri:noCountry></affiliation></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation wicri:level="3"><nlm:affiliation>Baylor College of Medicine, Houston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>Baylor College of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Kennedy, James L" sort="Kennedy, James L" uniqKey="Kennedy J" first="James L" last="Kennedy">James L. Kennedy</name><affiliation><nlm:affiliation>Centre for Addiction and Mental Health, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="King, Robert A" sort="King, Robert A" uniqKey="King R" first="Robert A" last="King">Robert A. King</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Kurlan, Roger" sort="Kurlan, Roger" uniqKey="Kurlan R" first="Roger" last="Kurlan">Roger Kurlan</name><affiliation wicri:level="2"><nlm:affiliation>Atlantic Neuroscience Institute, Summit, NJ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Atlantic Neuroscience Institute, Summit</wicri:cityArea></affiliation></author><author><name sortKey="Lanzagorta, Nuria" sort="Lanzagorta, Nuria" uniqKey="Lanzagorta N" first="Nuria" last="Lanzagorta">Nuria Lanzagorta</name><affiliation><nlm:affiliation>Carracci Medical Group, Mexico City.</nlm:affiliation><wicri:noCountry code="subField">Mexico City</wicri:noCountry></affiliation></author><author><name sortKey="Leboyer, Marion" sort="Leboyer, Marion" uniqKey="Leboyer M" first="Marion" last="Leboyer">Marion Leboyer</name><affiliation wicri:level="1"><nlm:affiliation>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; Institut Mondor de Recherche Biomédicale, Créteil, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; Institut Mondor de Recherche Biomédicale, Créteil</wicri:regionArea></affiliation></author><author><name sortKey="Leckman, James F" sort="Leckman, James F" uniqKey="Leckman J" first="James F" last="Leckman">James F. Leckman</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Lennertz, Leonhard" sort="Lennertz, Leonhard" uniqKey="Lennertz L" first="Leonhard" last="Lennertz">Leonhard Lennertz</name><affiliation wicri:level="1"><nlm:affiliation>University of Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Lochner, Christine" sort="Lochner, Christine" uniqKey="Lochner C" first="Christine" last="Lochner">Christine Lochner</name><affiliation wicri:level="1"><nlm:affiliation>University of Stellenbosch, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of Stellenbosch</wicri:regionArea></affiliation></author><author><name sortKey="Lowe, Thomas L" sort="Lowe, Thomas L" uniqKey="Lowe T" first="Thomas L" last="Lowe">Thomas L. Lowe</name><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation></author><author><name sortKey="Lyon, Gholson J" sort="Lyon, Gholson J" uniqKey="Lyon G" first="Gholson J" last="Lyon">Gholson J. Lyon</name><affiliation wicri:level="2"><nlm:affiliation>Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Cold Spring Harbor Laboratory, Cold Spring Harbor</wicri:cityArea></affiliation></author><author><name sortKey="Macciardi, Fabio" sort="Macciardi, Fabio" uniqKey="Macciardi F" first="Fabio" last="Macciardi">Fabio Macciardi</name><affiliation><nlm:affiliation>University of California, Irvine.</nlm:affiliation><wicri:noCountry code="subField">Irvine</wicri:noCountry></affiliation></author><author><name sortKey="Maier, Wolfgang" sort="Maier, Wolfgang" uniqKey="Maier W" first="Wolfgang" last="Maier">Wolfgang Maier</name><affiliation wicri:level="1"><nlm:affiliation>University of Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Mccracken, James T" sort="Mccracken, James T" uniqKey="Mccracken J" first="James T" last="Mccracken">James T. Mccracken</name><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation></author><author><name sortKey="Mcmahon, William" sort="Mcmahon, William" uniqKey="Mcmahon W" first="William" last="Mcmahon">William Mcmahon</name><affiliation><nlm:affiliation>University of Utah, Salt Lake City.</nlm:affiliation><wicri:noCountry code="subField">Salt Lake City</wicri:noCountry></affiliation></author><author><name sortKey="Murphy, Dennis L" sort="Murphy, Dennis L" uniqKey="Murphy D" first="Dennis L" last="Murphy">Dennis L. Murphy</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Naarden, Allan L" sort="Naarden, Allan L" uniqKey="Naarden A" first="Allan L" last="Naarden">Allan L. Naarden</name><affiliation><nlm:affiliation>Medical City Dallas Hospital.</nlm:affiliation><wicri:noCountry code="no comma">Medical City Dallas Hospital.</wicri:noCountry></affiliation></author><author><name sortKey="Neale, Benjamin M" sort="Neale, Benjamin M" uniqKey="Neale B" first="Benjamin M" last="Neale">Benjamin M. Neale</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Nurmi, Erika" sort="Nurmi, Erika" uniqKey="Nurmi E" first="Erika" last="Nurmi">Erika Nurmi</name><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation></author><author><name sortKey="Pakstis, Andrew J" sort="Pakstis, Andrew J" uniqKey="Pakstis A" first="Andrew J" last="Pakstis">Andrew J. Pakstis</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Pato, Michele T" sort="Pato, Michele T" uniqKey="Pato M" first="Michele T" last="Pato">Michele T. Pato</name><affiliation wicri:level="3"><nlm:affiliation>Zilkha Neurogenetic Institute, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Zilkha Neurogenetic Institute</wicri:orgArea></affiliation></author><author><name sortKey="Pato, Carlos N" sort="Pato, Carlos N" uniqKey="Pato C" first="Carlos N" last="Pato">Carlos N. Pato</name><affiliation wicri:level="3"><nlm:affiliation>Zilkha Neurogenetic Institute, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Zilkha Neurogenetic Institute</wicri:orgArea></affiliation></author><author><name sortKey="Piacentini, John" sort="Piacentini, John" uniqKey="Piacentini J" first="John" last="Piacentini">John Piacentini</name><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation></author><author><name sortKey="Pittenger, Christopher" sort="Pittenger, Christopher" uniqKey="Pittenger C" first="Christopher" last="Pittenger">Christopher Pittenger</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Pollak, Yehuda" sort="Pollak, Yehuda" uniqKey="Pollak Y" first="Yehuda" last="Pollak">Yehuda Pollak</name><affiliation><nlm:affiliation>Shaare Zedek Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation></author><author><name sortKey="Reus, Victor I" sort="Reus, Victor I" uniqKey="Reus V" first="Victor I" last="Reus">Victor I. Reus</name><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation></author><author><name sortKey="Richter, Margaret A" sort="Richter, Margaret A" uniqKey="Richter M" first="Margaret A" last="Richter">Margaret A. Richter</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Sunnybrook Health Sciences Centre, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Riddle, Mark" sort="Riddle, Mark" uniqKey="Riddle M" first="Mark" last="Riddle">Mark Riddle</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Robertson, Mary M" sort="Robertson, Mary M" uniqKey="Robertson M" first="Mary M" last="Robertson">Mary M. Robertson</name><affiliation><nlm:affiliation>University College London.</nlm:affiliation><wicri:noCountry code="no comma">University College London.</wicri:noCountry></affiliation></author><author><name sortKey="Rosenberg, David" sort="Rosenberg, David" uniqKey="Rosenberg D" first="David" last="Rosenberg">David Rosenberg</name><affiliation><nlm:affiliation>Wayne State University and Detroit Medical Center, Detroit.</nlm:affiliation><wicri:noCountry code="subField">Detroit</wicri:noCountry></affiliation></author><author><name sortKey="Rouleau, Guy A" sort="Rouleau, Guy A" uniqKey="Rouleau G" first="Guy A" last="Rouleau">Guy A. Rouleau</name><affiliation><nlm:affiliation>Montreal Neurological Institute.</nlm:affiliation><wicri:noCountry code="no comma">Montreal Neurological Institute.</wicri:noCountry></affiliation></author><author><name sortKey="Ruhrmann, Stephan" sort="Ruhrmann, Stephan" uniqKey="Ruhrmann S" first="Stephan" last="Ruhrmann">Stephan Ruhrmann</name><affiliation wicri:level="1"><nlm:affiliation>University of Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Sampaio, Aline S" sort="Sampaio, Aline S" uniqKey="Sampaio A" first="Aline S" last="Sampaio">Aline S. Sampaio</name><affiliation wicri:level="1"><nlm:affiliation>Federal University of São Paulo; Universidade Federal da Bahia, Salvador, Bahia, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Federal University of São Paulo; Universidade Federal da Bahia, Salvador, Bahia</wicri:regionArea></affiliation></author><author><name sortKey="Samuels, Jack" sort="Samuels, Jack" uniqKey="Samuels J" first="Jack" last="Samuels">Jack Samuels</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Sandor, Paul" sort="Sandor, Paul" uniqKey="Sandor P" first="Paul" last="Sandor">Paul Sandor</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Toronto Western Research Institute, University Health Network, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Sheppard, Brooke" sort="Sheppard, Brooke" uniqKey="Sheppard B" first="Brooke" last="Sheppard">Brooke Sheppard</name><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation></author><author><name sortKey="Singer, Harvey S" sort="Singer, Harvey S" uniqKey="Singer H" first="Harvey S" last="Singer">Harvey S. Singer</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Smit, Jan H" sort="Smit, Jan H" uniqKey="Smit J" first="Jan H" last="Smit">Jan H. Smit</name><affiliation wicri:level="3"><nlm:affiliation>VU Amsterdam and Erasmus University Medical Centre, Rotterdam; VU University Amsterdam; VU Medical Center, Amsterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName><wicri:orgArea>VU Amsterdam and Erasmus University Medical Centre, Rotterdam; VU University Amsterdam; VU Medical Center</wicri:orgArea></affiliation></author><author><name sortKey="Stein, Dan J" sort="Stein, Dan J" uniqKey="Stein D" first="Dan J" last="Stein">Dan J. Stein</name><affiliation wicri:level="1"><nlm:affiliation>University of Cape Town, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of Cape Town</wicri:regionArea></affiliation></author><author><name sortKey="Tischfield, Jay A" sort="Tischfield, Jay A" uniqKey="Tischfield J" first="Jay A" last="Tischfield">Jay A. Tischfield</name><affiliation wicri:level="2"><nlm:affiliation>Rutgers University, Piscataway Township, NJ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Rutgers University, Piscataway Township</wicri:cityArea></affiliation></author><author><name sortKey="Vallada, Homero" sort="Vallada, Homero" uniqKey="Vallada H" first="Homero" last="Vallada">Homero Vallada</name><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation></author><author><name sortKey="Veenstra Vanderweele, Jeremy" sort="Veenstra Vanderweele, Jeremy" uniqKey="Veenstra Vanderweele J" first="Jeremy" last="Veenstra-Vanderweele">Jeremy Veenstra-Vanderweele</name><affiliation wicri:level="2"><nlm:affiliation>Vanderbilt University, Nashville, TN.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Vanderbilt University, Nashville</wicri:cityArea></affiliation></author><author><name sortKey="Walitza, Susanne" sort="Walitza, Susanne" uniqKey="Walitza S" first="Susanne" last="Walitza">Susanne Walitza</name><affiliation><nlm:affiliation>University of Zurich; University of Würzburg.</nlm:affiliation><wicri:noCountry code="no comma">University of Zurich; University of Würzburg.</wicri:noCountry></affiliation></author><author><name sortKey="Wang, Ying" sort="Wang, Ying" uniqKey="Wang Y" first="Ying" last="Wang">Ying Wang</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Wendland, Jens R" sort="Wendland, Jens R" uniqKey="Wendland J" first="Jens R" last="Wendland">Jens R. Wendland</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Shugart, Yin Yao" sort="Shugart, Yin Yao" uniqKey="Shugart Y" first="Yin Yao" last="Shugart">Yin Yao Shugart</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Miguel, Euripedes C" sort="Miguel, Euripedes C" uniqKey="Miguel E" first="Euripedes C" last="Miguel">Euripedes C. Miguel</name><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation></author><author><name sortKey="Nicolini, Humberto" sort="Nicolini, Humberto" uniqKey="Nicolini H" first="Humberto" last="Nicolini">Humberto Nicolini</name><affiliation><nlm:affiliation>Carracci Medical Group, Mexico City.</nlm:affiliation><wicri:noCountry code="subField">Mexico City</wicri:noCountry></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation wicri:level="1"><nlm:affiliation>Erasmus Medical Center Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Erasmus Medical Center Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Moessner, Rainald" sort="Moessner, Rainald" uniqKey="Moessner R" first="Rainald" last="Moessner">Rainald Moessner</name><affiliation wicri:level="1"><nlm:affiliation>University of Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Wagner, Michael" sort="Wagner, Michael" uniqKey="Wagner M" first="Michael" last="Wagner">Michael Wagner</name><affiliation wicri:level="1"><nlm:affiliation>University of Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Ruiz Linares, Andres" sort="Ruiz Linares, Andres" uniqKey="Ruiz Linares A" first="Andres" last="Ruiz-Linares">Andres Ruiz-Linares</name><affiliation><nlm:affiliation>University College London.</nlm:affiliation><wicri:noCountry code="no comma">University College London.</wicri:noCountry></affiliation></author><author><name sortKey="Heutink, Peter" sort="Heutink, Peter" uniqKey="Heutink P" first="Peter" last="Heutink">Peter Heutink</name><affiliation><nlm:affiliation>German Center for Neurodegenerative Diseases, Bonn and VU Medical Center Amsterdam.</nlm:affiliation><wicri:noCountry code="subField">Bonn and VU Medical Center Amsterdam</wicri:noCountry></affiliation></author><author><name sortKey="Nestadt, Gerald" sort="Nestadt, Gerald" uniqKey="Nestadt G" first="Gerald" last="Nestadt">Gerald Nestadt</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Freimer, Nelson" sort="Freimer, Nelson" uniqKey="Freimer N" first="Nelson" last="Freimer">Nelson Freimer</name><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine; Semel Institute for Neuroscience and Human Behavior, UCLA.</nlm:affiliation><wicri:noCountry code="subField">UCLA</wicri:noCountry></affiliation></author><author><name sortKey="Petryshen, Tracey" sort="Petryshen, Tracey" uniqKey="Petryshen T" first="Tracey" last="Petryshen">Tracey Petryshen</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Posthuma, Danielle" sort="Posthuma, Danielle" uniqKey="Posthuma D" first="Danielle" last="Posthuma">Danielle Posthuma</name><affiliation wicri:level="3"><nlm:affiliation>VU Amsterdam and Erasmus University Medical Centre, Rotterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName><wicri:orgArea>VU Amsterdam and Erasmus University Medical Centre</wicri:orgArea></affiliation></author><author><name sortKey="Jenike, Michael A" sort="Jenike, Michael A" uniqKey="Jenike M" first="Michael A" last="Jenike">Michael A. Jenike</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Cox, Nancy J" sort="Cox, Nancy J" uniqKey="Cox N" first="Nancy J" last="Cox">Nancy J. Cox</name><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation></author><author><name sortKey="Hanna, Gregory L" sort="Hanna, Gregory L" uniqKey="Hanna G" first="Gregory L" last="Hanna">Gregory L. Hanna</name><affiliation wicri:level="2"><nlm:affiliation>University of Michigan, Ann Arbor, MI.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Michigan</region></placeName><wicri:cityArea>University of Michigan, Ann Arbor</wicri:cityArea></affiliation></author><author><name sortKey="Brentani, Helena" sort="Brentani, Helena" uniqKey="Brentani H" first="Helena" last="Brentani">Helena Brentani</name><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation></author><author><name sortKey="Scherer, Stephen W" sort="Scherer, Stephen W" uniqKey="Scherer S" first="Stephen W" last="Scherer">Stephen W. Scherer</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Arnold, Paul D" sort="Arnold, Paul D" uniqKey="Arnold P" first="Paul D" last="Arnold">Paul D. Arnold</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Stewart, S Evelyn" sort="Stewart, S Evelyn" uniqKey="Stewart S" first="S Evelyn" last="Stewart">S Evelyn Stewart</name><affiliation><nlm:affiliation>Massachusetts General Hospital, Boston; University of British Columbia, Vancouver.</nlm:affiliation><wicri:noCountry code="subField">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="Mathews, Carol A" sort="Mathews, Carol A" uniqKey="Mathews C" first="Carol A" last="Mathews">Carol A. Mathews</name><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation></author><author><name sortKey="Knowles, James A" sort="Knowles, James A" uniqKey="Knowles J" first="James A" last="Knowles">James A. Knowles</name><affiliation wicri:level="3"><nlm:affiliation>Zilkha Neurogenetic Institute, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Zilkha Neurogenetic Institute</wicri:orgArea></affiliation></author><author><name sortKey="Cook, Edwin H" sort="Cook, Edwin H" uniqKey="Cook E" first="Edwin H" last="Cook">Edwin H. Cook</name><affiliation><nlm:affiliation>University of Illinois at Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Illinois at Chicago.</wicri:noCountry></affiliation></author><author><name sortKey="Pauls, David L" sort="Pauls, David L" uniqKey="Pauls D" first="David L" last="Pauls">David L. Pauls</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Wang, Kai" sort="Wang, Kai" uniqKey="Wang K" first="Kai" last="Wang">Kai Wang</name><affiliation wicri:level="3"><nlm:affiliation>Zilkha Neurogenetic Institute, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Zilkha Neurogenetic Institute</wicri:orgArea></affiliation></author><author><name sortKey="Scharf, Jeremiah M" sort="Scharf, Jeremiah M" uniqKey="Scharf J" first="Jeremiah M" last="Scharf">Jeremiah M. Scharf</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute, Boston. Electronic address: jscharf@partners.org.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:25062598</idno><idno type="pmid">25062598</idno><idno type="doi">10.1016/j.jaac.2014.04.022</idno><idno type="wicri:Area/PubMed/Corpus">003573</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003573</idno><idno type="wicri:Area/PubMed/Curation">003460</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003460</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.</title><author><name sortKey="Mcgrath, Lauren M" sort="Mcgrath, Lauren M" uniqKey="Mcgrath L" first="Lauren M" last="Mcgrath">Lauren M. Mcgrath</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; American University, Washington, DC; Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; American University, Washington, DC; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Yu, Dongmei" sort="Yu, Dongmei" uniqKey="Yu D" first="Dongmei" last="Yu">Dongmei Yu</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Marshall, Christian" sort="Marshall, Christian" uniqKey="Marshall C" first="Christian" last="Marshall">Christian Marshall</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Davis, Lea K" sort="Davis, Lea K" uniqKey="Davis L" first="Lea K" last="Davis">Lea K. Davis</name><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation></author><author><name sortKey="Thiruvahindrapuram, Bhooma" sort="Thiruvahindrapuram, Bhooma" uniqKey="Thiruvahindrapuram B" first="Bhooma" last="Thiruvahindrapuram">Bhooma Thiruvahindrapuram</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Li, Bingbin" sort="Li, Bingbin" uniqKey="Li B" first="Bingbin" last="Li">Bingbin Li</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Cappi, Carolina" sort="Cappi, Carolina" uniqKey="Cappi C" first="Carolina" last="Cappi">Carolina Cappi</name><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation></author><author><name sortKey="Gerber, Gloria" sort="Gerber, Gloria" uniqKey="Gerber G" first="Gloria" last="Gerber">Gloria Gerber</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Wolf, Aaron" sort="Wolf, Aaron" uniqKey="Wolf A" first="Aaron" last="Wolf">Aaron Wolf</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Schroeder, Frederick A" sort="Schroeder, Frederick A" uniqKey="Schroeder F" first="Frederick A" last="Schroeder">Frederick A. Schroeder</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Osiecki, Lisa" sort="Osiecki, Lisa" uniqKey="Osiecki L" first="Lisa" last="Osiecki">Lisa Osiecki</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="O Dushlaine, Colm" sort="O Dushlaine, Colm" uniqKey="O Dushlaine C" first="Colm" last="O'Dushlaine">Colm O'Dushlaine</name><affiliation wicri:level="3"><nlm:affiliation>Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Kirby, Andrew" sort="Kirby, Andrew" uniqKey="Kirby A" first="Andrew" last="Kirby">Andrew Kirby</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Illmann, Cornelia" sort="Illmann, Cornelia" uniqKey="Illmann C" first="Cornelia" last="Illmann">Cornelia Illmann</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Haddad, Stephen" sort="Haddad, Stephen" uniqKey="Haddad S" first="Stephen" last="Haddad">Stephen Haddad</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Gallagher, Patience" sort="Gallagher, Patience" uniqKey="Gallagher P" first="Patience" last="Gallagher">Patience Gallagher</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Fagerness, Jesen A" sort="Fagerness, Jesen A" uniqKey="Fagerness J" first="Jesen A" last="Fagerness">Jesen A. Fagerness</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Barr, Cathy L" sort="Barr, Cathy L" uniqKey="Barr C" first="Cathy L" last="Barr">Cathy L. Barr</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Toronto Western Research Institute, University Health Network, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Bellodi, Laura" sort="Bellodi, Laura" uniqKey="Bellodi L" first="Laura" last="Bellodi">Laura Bellodi</name><affiliation wicri:level="3"><nlm:affiliation>Università Vita-Salute San Raffaele, Milan.</nlm:affiliation><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName><wicri:orgArea>Università Vita-Salute San Raffaele</wicri:orgArea></affiliation></author><author><name sortKey="Benarroch, Fortu" sort="Benarroch, Fortu" uniqKey="Benarroch F" first="Fortu" last="Benarroch">Fortu Benarroch</name><affiliation><nlm:affiliation>Hadassah-Hebrew University Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation></author><author><name sortKey="Bienvenu, O Joseph" sort="Bienvenu, O Joseph" uniqKey="Bienvenu O" first="O Joseph" last="Bienvenu">O Joseph Bienvenu</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Black, Donald W" sort="Black, Donald W" uniqKey="Black D" first="Donald W" last="Black">Donald W. Black</name><affiliation><nlm:affiliation>University of Iowa College of Medicine, Iowa City.</nlm:affiliation><wicri:noCountry code="subField">Iowa City</wicri:noCountry></affiliation></author><author><name sortKey="Bloch, Michael H" sort="Bloch, Michael H" uniqKey="Bloch M" first="Michael H" last="Bloch">Michael H. Bloch</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Bruun, Ruth D" sort="Bruun, Ruth D" uniqKey="Bruun R" first="Ruth D" last="Bruun">Ruth D. Bruun</name><affiliation wicri:level="2"><nlm:affiliation>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; New York University Medical Center, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; New York University Medical Center</wicri:cityArea></affiliation></author><author><name sortKey="Budman, Cathy L" sort="Budman, Cathy L" uniqKey="Budman C" first="Cathy L" last="Budman">Cathy L. Budman</name><affiliation wicri:level="2"><nlm:affiliation>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; Hofstra University School of Medicine, Hempstead, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; Hofstra University School of Medicine, Hempstead</wicri:cityArea></affiliation></author><author><name sortKey="Camarena, Beatriz" sort="Camarena, Beatriz" uniqKey="Camarena B" first="Beatriz" last="Camarena">Beatriz Camarena</name><affiliation wicri:level="1"><nlm:affiliation>Instituto Nacional de Psiquiatría Ramon de la Fuente Muñiz, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Instituto Nacional de Psiquiatría Ramon de la Fuente Muñiz</wicri:regionArea></affiliation></author><author><name sortKey="Cath, Danielle C" sort="Cath, Danielle C" uniqKey="Cath D" first="Danielle C" last="Cath">Danielle C. Cath</name><affiliation wicri:level="3"><nlm:affiliation>Utrecht University and VU Medical Center, Amsterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName><wicri:orgArea>Utrecht University and VU Medical Center</wicri:orgArea></affiliation></author><author><name sortKey="Cavallini, Maria C" sort="Cavallini, Maria C" uniqKey="Cavallini M" first="Maria C" last="Cavallini">Maria C. Cavallini</name><affiliation wicri:level="3"><nlm:affiliation>Ospedale San Raffaele, Milan.</nlm:affiliation><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName><wicri:orgArea>Ospedale San Raffaele</wicri:orgArea></affiliation></author><author><name sortKey="Chouinard, Sylvain" sort="Chouinard, Sylvain" uniqKey="Chouinard S" first="Sylvain" last="Chouinard">Sylvain Chouinard</name><affiliation><nlm:affiliation>University of Montreal.</nlm:affiliation><wicri:noCountry code="no comma">University of Montreal.</wicri:noCountry></affiliation></author><author><name sortKey="Coric, Vladimir" sort="Coric, Vladimir" uniqKey="Coric V" first="Vladimir" last="Coric">Vladimir Coric</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Cullen, Bernadette" sort="Cullen, Bernadette" uniqKey="Cullen B" first="Bernadette" last="Cullen">Bernadette Cullen</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Delorme, Richard" sort="Delorme, Richard" uniqKey="Delorme R" first="Richard" last="Delorme">Richard Delorme</name><affiliation wicri:level="3"><nlm:affiliation>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; Institut Pasteur, Paris.</nlm:affiliation><country>France</country><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName><wicri:orgArea>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; Institut Pasteur</wicri:orgArea></affiliation></author><author><name sortKey="Denys, Damiaan" sort="Denys, Damiaan" uniqKey="Denys D" first="Damiaan" last="Denys">Damiaan Denys</name><affiliation wicri:level="3"><nlm:affiliation>Netherlands Institute for Neuroscience, Amsterdam; Academic Medical Center, Amsterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName><wicri:orgArea>Netherlands Institute for Neuroscience, Amsterdam; Academic Medical Center</wicri:orgArea></affiliation></author><author><name sortKey="Derks, Eske M" sort="Derks, Eske M" uniqKey="Derks E" first="Eske M" last="Derks">Eske M. Derks</name><affiliation wicri:level="3"><nlm:affiliation>Academic Medical Center, Amsterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName><wicri:orgArea>Academic Medical Center</wicri:orgArea></affiliation></author><author><name sortKey="Dion, Yves" sort="Dion, Yves" uniqKey="Dion Y" first="Yves" last="Dion">Yves Dion</name><affiliation><nlm:affiliation>University of Montreal.</nlm:affiliation><wicri:noCountry code="no comma">University of Montreal.</wicri:noCountry></affiliation></author><author><name sortKey="Rosario, Maria C" sort="Rosario, Maria C" uniqKey="Rosario M" first="Maria C" last="Rosário">Maria C. Rosário</name><affiliation><nlm:affiliation>Federal University of São Paulo.</nlm:affiliation><wicri:noCountry code="no comma">Federal University of São Paulo.</wicri:noCountry></affiliation></author><author><name sortKey="Eapen, Valsama" sort="Eapen, Valsama" uniqKey="Eapen V" first="Valsama" last="Eapen">Valsama Eapen</name><affiliation wicri:level="1"><nlm:affiliation>University of New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Evans, Patrick" sort="Evans, Patrick" uniqKey="Evans P" first="Patrick" last="Evans">Patrick Evans</name><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation></author><author><name sortKey="Falkai, Peter" sort="Falkai, Peter" uniqKey="Falkai P" first="Peter" last="Falkai">Peter Falkai</name><affiliation><nlm:affiliation>University of Munich.</nlm:affiliation><wicri:noCountry code="no comma">University of Munich.</wicri:noCountry></affiliation></author><author><name sortKey="Fernandez, Thomas V" sort="Fernandez, Thomas V" uniqKey="Fernandez T" first="Thomas V" last="Fernandez">Thomas V. Fernandez</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Garrido, Helena" sort="Garrido, Helena" uniqKey="Garrido H" first="Helena" last="Garrido">Helena Garrido</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Nacional de Niños, San Jose, Costa Rica; Clinica Herrera Amighetti, Avenida Escazú, San José, Costa Rica.</nlm:affiliation><country xml:lang="fr">Costa Rica</country><wicri:regionArea>Hospital Nacional de Niños, San Jose, Costa Rica; Clinica Herrera Amighetti, Avenida Escazú, San José</wicri:regionArea></affiliation></author><author><name sortKey="Geller, Daniel" sort="Geller, Daniel" uniqKey="Geller D" first="Daniel" last="Geller">Daniel Geller</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Grabe, Hans J" sort="Grabe, Hans J" uniqKey="Grabe H" first="Hans J" last="Grabe">Hans J. Grabe</name><affiliation wicri:level="1"><nlm:affiliation>University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Medicine Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Grados, Marco A" sort="Grados, Marco A" uniqKey="Grados M" first="Marco A" last="Grados">Marco A. Grados</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Greenberg, Benjamin D" sort="Greenberg, Benjamin D" uniqKey="Greenberg B" first="Benjamin D" last="Greenberg">Benjamin D. Greenberg</name><affiliation wicri:level="2"><nlm:affiliation>Brown Medical School, Providence, RI.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Rhode Island</region></placeName><wicri:cityArea>Brown Medical School, Providence</wicri:cityArea></affiliation></author><author><name sortKey="Gross Tsur, Varda" sort="Gross Tsur, Varda" uniqKey="Gross Tsur V" first="Varda" last="Gross-Tsur">Varda Gross-Tsur</name><affiliation><nlm:affiliation>Shaare Zedek Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation></author><author><name sortKey="Grunblatt, Edna" sort="Grunblatt, Edna" uniqKey="Grunblatt E" first="Edna" last="Grünblatt">Edna Grünblatt</name><affiliation><nlm:affiliation>University of Zurich.</nlm:affiliation><wicri:noCountry code="no comma">University of Zurich.</wicri:noCountry></affiliation></author><author><name sortKey="Heiman, Gary A" sort="Heiman, Gary A" uniqKey="Heiman G" first="Gary A" last="Heiman">Gary A. Heiman</name><affiliation wicri:level="2"><nlm:affiliation>Rutgers University, Piscataway Township, NJ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Rutgers University, Piscataway Township</wicri:cityArea></affiliation></author><author><name sortKey="Hemmings, Sian M J" sort="Hemmings, Sian M J" uniqKey="Hemmings S" first="Sian M J" last="Hemmings">Sian M J. Hemmings</name><affiliation wicri:level="1"><nlm:affiliation>University of Stellenbosch, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of Stellenbosch</wicri:regionArea></affiliation></author><author><name sortKey="Herrera, Luis D" sort="Herrera, Luis D" uniqKey="Herrera L" first="Luis D" last="Herrera">Luis D. Herrera</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Nacional de Niños, San Jose, Costa Rica.</nlm:affiliation><country xml:lang="fr">Costa Rica</country><wicri:regionArea>Hospital Nacional de Niños, San Jose</wicri:regionArea></affiliation></author><author><name sortKey="Hounie, Ana G" sort="Hounie, Ana G" uniqKey="Hounie A" first="Ana G" last="Hounie">Ana G. Hounie</name><affiliation><nlm:affiliation>Federal University of São Paulo.</nlm:affiliation><wicri:noCountry code="no comma">Federal University of São Paulo.</wicri:noCountry></affiliation></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation wicri:level="3"><nlm:affiliation>Baylor College of Medicine, Houston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>Baylor College of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Kennedy, James L" sort="Kennedy, James L" uniqKey="Kennedy J" first="James L" last="Kennedy">James L. Kennedy</name><affiliation><nlm:affiliation>Centre for Addiction and Mental Health, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="King, Robert A" sort="King, Robert A" uniqKey="King R" first="Robert A" last="King">Robert A. King</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Kurlan, Roger" sort="Kurlan, Roger" uniqKey="Kurlan R" first="Roger" last="Kurlan">Roger Kurlan</name><affiliation wicri:level="2"><nlm:affiliation>Atlantic Neuroscience Institute, Summit, NJ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Atlantic Neuroscience Institute, Summit</wicri:cityArea></affiliation></author><author><name sortKey="Lanzagorta, Nuria" sort="Lanzagorta, Nuria" uniqKey="Lanzagorta N" first="Nuria" last="Lanzagorta">Nuria Lanzagorta</name><affiliation><nlm:affiliation>Carracci Medical Group, Mexico City.</nlm:affiliation><wicri:noCountry code="subField">Mexico City</wicri:noCountry></affiliation></author><author><name sortKey="Leboyer, Marion" sort="Leboyer, Marion" uniqKey="Leboyer M" first="Marion" last="Leboyer">Marion Leboyer</name><affiliation wicri:level="1"><nlm:affiliation>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; Institut Mondor de Recherche Biomédicale, Créteil, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; Institut Mondor de Recherche Biomédicale, Créteil</wicri:regionArea></affiliation></author><author><name sortKey="Leckman, James F" sort="Leckman, James F" uniqKey="Leckman J" first="James F" last="Leckman">James F. Leckman</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Lennertz, Leonhard" sort="Lennertz, Leonhard" uniqKey="Lennertz L" first="Leonhard" last="Lennertz">Leonhard Lennertz</name><affiliation wicri:level="1"><nlm:affiliation>University of Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Lochner, Christine" sort="Lochner, Christine" uniqKey="Lochner C" first="Christine" last="Lochner">Christine Lochner</name><affiliation wicri:level="1"><nlm:affiliation>University of Stellenbosch, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of Stellenbosch</wicri:regionArea></affiliation></author><author><name sortKey="Lowe, Thomas L" sort="Lowe, Thomas L" uniqKey="Lowe T" first="Thomas L" last="Lowe">Thomas L. Lowe</name><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation></author><author><name sortKey="Lyon, Gholson J" sort="Lyon, Gholson J" uniqKey="Lyon G" first="Gholson J" last="Lyon">Gholson J. Lyon</name><affiliation wicri:level="2"><nlm:affiliation>Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Cold Spring Harbor Laboratory, Cold Spring Harbor</wicri:cityArea></affiliation></author><author><name sortKey="Macciardi, Fabio" sort="Macciardi, Fabio" uniqKey="Macciardi F" first="Fabio" last="Macciardi">Fabio Macciardi</name><affiliation><nlm:affiliation>University of California, Irvine.</nlm:affiliation><wicri:noCountry code="subField">Irvine</wicri:noCountry></affiliation></author><author><name sortKey="Maier, Wolfgang" sort="Maier, Wolfgang" uniqKey="Maier W" first="Wolfgang" last="Maier">Wolfgang Maier</name><affiliation wicri:level="1"><nlm:affiliation>University of Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Mccracken, James T" sort="Mccracken, James T" uniqKey="Mccracken J" first="James T" last="Mccracken">James T. Mccracken</name><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation></author><author><name sortKey="Mcmahon, William" sort="Mcmahon, William" uniqKey="Mcmahon W" first="William" last="Mcmahon">William Mcmahon</name><affiliation><nlm:affiliation>University of Utah, Salt Lake City.</nlm:affiliation><wicri:noCountry code="subField">Salt Lake City</wicri:noCountry></affiliation></author><author><name sortKey="Murphy, Dennis L" sort="Murphy, Dennis L" uniqKey="Murphy D" first="Dennis L" last="Murphy">Dennis L. Murphy</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Naarden, Allan L" sort="Naarden, Allan L" uniqKey="Naarden A" first="Allan L" last="Naarden">Allan L. Naarden</name><affiliation><nlm:affiliation>Medical City Dallas Hospital.</nlm:affiliation><wicri:noCountry code="no comma">Medical City Dallas Hospital.</wicri:noCountry></affiliation></author><author><name sortKey="Neale, Benjamin M" sort="Neale, Benjamin M" uniqKey="Neale B" first="Benjamin M" last="Neale">Benjamin M. Neale</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Nurmi, Erika" sort="Nurmi, Erika" uniqKey="Nurmi E" first="Erika" last="Nurmi">Erika Nurmi</name><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation></author><author><name sortKey="Pakstis, Andrew J" sort="Pakstis, Andrew J" uniqKey="Pakstis A" first="Andrew J" last="Pakstis">Andrew J. Pakstis</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Pato, Michele T" sort="Pato, Michele T" uniqKey="Pato M" first="Michele T" last="Pato">Michele T. Pato</name><affiliation wicri:level="3"><nlm:affiliation>Zilkha Neurogenetic Institute, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Zilkha Neurogenetic Institute</wicri:orgArea></affiliation></author><author><name sortKey="Pato, Carlos N" sort="Pato, Carlos N" uniqKey="Pato C" first="Carlos N" last="Pato">Carlos N. Pato</name><affiliation wicri:level="3"><nlm:affiliation>Zilkha Neurogenetic Institute, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Zilkha Neurogenetic Institute</wicri:orgArea></affiliation></author><author><name sortKey="Piacentini, John" sort="Piacentini, John" uniqKey="Piacentini J" first="John" last="Piacentini">John Piacentini</name><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine.</nlm:affiliation><wicri:noCountry code="subField">Los Angeles (UCLA) School of Medicine</wicri:noCountry></affiliation></author><author><name sortKey="Pittenger, Christopher" sort="Pittenger, Christopher" uniqKey="Pittenger C" first="Christopher" last="Pittenger">Christopher Pittenger</name><affiliation wicri:level="2"><nlm:affiliation>Yale University School of Medicine, New Haven, CT.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Pollak, Yehuda" sort="Pollak, Yehuda" uniqKey="Pollak Y" first="Yehuda" last="Pollak">Yehuda Pollak</name><affiliation><nlm:affiliation>Shaare Zedek Medical Center, Jerusalem.</nlm:affiliation><wicri:noCountry code="subField">Jerusalem</wicri:noCountry></affiliation></author><author><name sortKey="Reus, Victor I" sort="Reus, Victor I" uniqKey="Reus V" first="Victor I" last="Reus">Victor I. Reus</name><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation></author><author><name sortKey="Richter, Margaret A" sort="Richter, Margaret A" uniqKey="Richter M" first="Margaret A" last="Richter">Margaret A. Richter</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Sunnybrook Health Sciences Centre, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Riddle, Mark" sort="Riddle, Mark" uniqKey="Riddle M" first="Mark" last="Riddle">Mark Riddle</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Robertson, Mary M" sort="Robertson, Mary M" uniqKey="Robertson M" first="Mary M" last="Robertson">Mary M. Robertson</name><affiliation><nlm:affiliation>University College London.</nlm:affiliation><wicri:noCountry code="no comma">University College London.</wicri:noCountry></affiliation></author><author><name sortKey="Rosenberg, David" sort="Rosenberg, David" uniqKey="Rosenberg D" first="David" last="Rosenberg">David Rosenberg</name><affiliation><nlm:affiliation>Wayne State University and Detroit Medical Center, Detroit.</nlm:affiliation><wicri:noCountry code="subField">Detroit</wicri:noCountry></affiliation></author><author><name sortKey="Rouleau, Guy A" sort="Rouleau, Guy A" uniqKey="Rouleau G" first="Guy A" last="Rouleau">Guy A. Rouleau</name><affiliation><nlm:affiliation>Montreal Neurological Institute.</nlm:affiliation><wicri:noCountry code="no comma">Montreal Neurological Institute.</wicri:noCountry></affiliation></author><author><name sortKey="Ruhrmann, Stephan" sort="Ruhrmann, Stephan" uniqKey="Ruhrmann S" first="Stephan" last="Ruhrmann">Stephan Ruhrmann</name><affiliation wicri:level="1"><nlm:affiliation>University of Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Sampaio, Aline S" sort="Sampaio, Aline S" uniqKey="Sampaio A" first="Aline S" last="Sampaio">Aline S. Sampaio</name><affiliation wicri:level="1"><nlm:affiliation>Federal University of São Paulo; Universidade Federal da Bahia, Salvador, Bahia, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Federal University of São Paulo; Universidade Federal da Bahia, Salvador, Bahia</wicri:regionArea></affiliation></author><author><name sortKey="Samuels, Jack" sort="Samuels, Jack" uniqKey="Samuels J" first="Jack" last="Samuels">Jack Samuels</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Sandor, Paul" sort="Sandor, Paul" uniqKey="Sandor P" first="Paul" last="Sandor">Paul Sandor</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Toronto Western Research Institute, University Health Network, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Sheppard, Brooke" sort="Sheppard, Brooke" uniqKey="Sheppard B" first="Brooke" last="Sheppard">Brooke Sheppard</name><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation></author><author><name sortKey="Singer, Harvey S" sort="Singer, Harvey S" uniqKey="Singer H" first="Harvey S" last="Singer">Harvey S. Singer</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Smit, Jan H" sort="Smit, Jan H" uniqKey="Smit J" first="Jan H" last="Smit">Jan H. Smit</name><affiliation wicri:level="3"><nlm:affiliation>VU Amsterdam and Erasmus University Medical Centre, Rotterdam; VU University Amsterdam; VU Medical Center, Amsterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName><wicri:orgArea>VU Amsterdam and Erasmus University Medical Centre, Rotterdam; VU University Amsterdam; VU Medical Center</wicri:orgArea></affiliation></author><author><name sortKey="Stein, Dan J" sort="Stein, Dan J" uniqKey="Stein D" first="Dan J" last="Stein">Dan J. Stein</name><affiliation wicri:level="1"><nlm:affiliation>University of Cape Town, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of Cape Town</wicri:regionArea></affiliation></author><author><name sortKey="Tischfield, Jay A" sort="Tischfield, Jay A" uniqKey="Tischfield J" first="Jay A" last="Tischfield">Jay A. Tischfield</name><affiliation wicri:level="2"><nlm:affiliation>Rutgers University, Piscataway Township, NJ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Rutgers University, Piscataway Township</wicri:cityArea></affiliation></author><author><name sortKey="Vallada, Homero" sort="Vallada, Homero" uniqKey="Vallada H" first="Homero" last="Vallada">Homero Vallada</name><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation></author><author><name sortKey="Veenstra Vanderweele, Jeremy" sort="Veenstra Vanderweele, Jeremy" uniqKey="Veenstra Vanderweele J" first="Jeremy" last="Veenstra-Vanderweele">Jeremy Veenstra-Vanderweele</name><affiliation wicri:level="2"><nlm:affiliation>Vanderbilt University, Nashville, TN.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Vanderbilt University, Nashville</wicri:cityArea></affiliation></author><author><name sortKey="Walitza, Susanne" sort="Walitza, Susanne" uniqKey="Walitza S" first="Susanne" last="Walitza">Susanne Walitza</name><affiliation><nlm:affiliation>University of Zurich; University of Würzburg.</nlm:affiliation><wicri:noCountry code="no comma">University of Zurich; University of Würzburg.</wicri:noCountry></affiliation></author><author><name sortKey="Wang, Ying" sort="Wang, Ying" uniqKey="Wang Y" first="Ying" last="Wang">Ying Wang</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Wendland, Jens R" sort="Wendland, Jens R" uniqKey="Wendland J" first="Jens R" last="Wendland">Jens R. Wendland</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Shugart, Yin Yao" sort="Shugart, Yin Yao" uniqKey="Shugart Y" first="Yin Yao" last="Shugart">Yin Yao Shugart</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institute of Mental Health (NIMH) Intramural Research Program, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Miguel, Euripedes C" sort="Miguel, Euripedes C" uniqKey="Miguel E" first="Euripedes C" last="Miguel">Euripedes C. Miguel</name><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation></author><author><name sortKey="Nicolini, Humberto" sort="Nicolini, Humberto" uniqKey="Nicolini H" first="Humberto" last="Nicolini">Humberto Nicolini</name><affiliation><nlm:affiliation>Carracci Medical Group, Mexico City.</nlm:affiliation><wicri:noCountry code="subField">Mexico City</wicri:noCountry></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation wicri:level="1"><nlm:affiliation>Erasmus Medical Center Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Erasmus Medical Center Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Moessner, Rainald" sort="Moessner, Rainald" uniqKey="Moessner R" first="Rainald" last="Moessner">Rainald Moessner</name><affiliation wicri:level="1"><nlm:affiliation>University of Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Wagner, Michael" sort="Wagner, Michael" uniqKey="Wagner M" first="Michael" last="Wagner">Michael Wagner</name><affiliation wicri:level="1"><nlm:affiliation>University of Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Ruiz Linares, Andres" sort="Ruiz Linares, Andres" uniqKey="Ruiz Linares A" first="Andres" last="Ruiz-Linares">Andres Ruiz-Linares</name><affiliation><nlm:affiliation>University College London.</nlm:affiliation><wicri:noCountry code="no comma">University College London.</wicri:noCountry></affiliation></author><author><name sortKey="Heutink, Peter" sort="Heutink, Peter" uniqKey="Heutink P" first="Peter" last="Heutink">Peter Heutink</name><affiliation><nlm:affiliation>German Center for Neurodegenerative Diseases, Bonn and VU Medical Center Amsterdam.</nlm:affiliation><wicri:noCountry code="subField">Bonn and VU Medical Center Amsterdam</wicri:noCountry></affiliation></author><author><name sortKey="Nestadt, Gerald" sort="Nestadt, Gerald" uniqKey="Nestadt G" first="Gerald" last="Nestadt">Gerald Nestadt</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins University School of Medicine, Baltimore.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><wicri:orgArea>Johns Hopkins University School of Medicine</wicri:orgArea></affiliation></author><author><name sortKey="Freimer, Nelson" sort="Freimer, Nelson" uniqKey="Freimer N" first="Nelson" last="Freimer">Nelson Freimer</name><affiliation><nlm:affiliation>University of California, Los Angeles (UCLA) School of Medicine; Semel Institute for Neuroscience and Human Behavior, UCLA.</nlm:affiliation><wicri:noCountry code="subField">UCLA</wicri:noCountry></affiliation></author><author><name sortKey="Petryshen, Tracey" sort="Petryshen, Tracey" uniqKey="Petryshen T" first="Tracey" last="Petryshen">Tracey Petryshen</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author><author><name sortKey="Posthuma, Danielle" sort="Posthuma, Danielle" uniqKey="Posthuma D" first="Danielle" last="Posthuma">Danielle Posthuma</name><affiliation wicri:level="3"><nlm:affiliation>VU Amsterdam and Erasmus University Medical Centre, Rotterdam.</nlm:affiliation><country>Pays-Bas</country><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName><wicri:orgArea>VU Amsterdam and Erasmus University Medical Centre</wicri:orgArea></affiliation></author><author><name sortKey="Jenike, Michael A" sort="Jenike, Michael A" uniqKey="Jenike M" first="Michael A" last="Jenike">Michael A. Jenike</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Cox, Nancy J" sort="Cox, Nancy J" uniqKey="Cox N" first="Nancy J" last="Cox">Nancy J. Cox</name><affiliation><nlm:affiliation>University of Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Chicago.</wicri:noCountry></affiliation></author><author><name sortKey="Hanna, Gregory L" sort="Hanna, Gregory L" uniqKey="Hanna G" first="Gregory L" last="Hanna">Gregory L. Hanna</name><affiliation wicri:level="2"><nlm:affiliation>University of Michigan, Ann Arbor, MI.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Michigan</region></placeName><wicri:cityArea>University of Michigan, Ann Arbor</wicri:cityArea></affiliation></author><author><name sortKey="Brentani, Helena" sort="Brentani, Helena" uniqKey="Brentani H" first="Helena" last="Brentani">Helena Brentani</name><affiliation><nlm:affiliation>University of São Paulo Medical School.</nlm:affiliation><wicri:noCountry code="no comma">University of São Paulo Medical School.</wicri:noCountry></affiliation></author><author><name sortKey="Scherer, Stephen W" sort="Scherer, Stephen W" uniqKey="Scherer S" first="Stephen W" last="Scherer">Stephen W. Scherer</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Arnold, Paul D" sort="Arnold, Paul D" uniqKey="Arnold P" first="Paul D" last="Arnold">Paul D. Arnold</name><affiliation><nlm:affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</nlm:affiliation><wicri:noCountry code="subField">Toronto</wicri:noCountry></affiliation></author><author><name sortKey="Stewart, S Evelyn" sort="Stewart, S Evelyn" uniqKey="Stewart S" first="S Evelyn" last="Stewart">S Evelyn Stewart</name><affiliation><nlm:affiliation>Massachusetts General Hospital, Boston; University of British Columbia, Vancouver.</nlm:affiliation><wicri:noCountry code="subField">Vancouver</wicri:noCountry></affiliation></author><author><name sortKey="Mathews, Carol A" sort="Mathews, Carol A" uniqKey="Mathews C" first="Carol A" last="Mathews">Carol A. Mathews</name><affiliation><nlm:affiliation>University of California at San Francisco School of Medicine.</nlm:affiliation><wicri:noCountry code="no comma">University of California at San Francisco School of Medicine.</wicri:noCountry></affiliation></author><author><name sortKey="Knowles, James A" sort="Knowles, James A" uniqKey="Knowles J" first="James A" last="Knowles">James A. Knowles</name><affiliation wicri:level="3"><nlm:affiliation>Zilkha Neurogenetic Institute, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Zilkha Neurogenetic Institute</wicri:orgArea></affiliation></author><author><name sortKey="Cook, Edwin H" sort="Cook, Edwin H" uniqKey="Cook E" first="Edwin H" last="Cook">Edwin H. Cook</name><affiliation><nlm:affiliation>University of Illinois at Chicago.</nlm:affiliation><wicri:noCountry code="no comma">University of Illinois at Chicago.</wicri:noCountry></affiliation></author><author><name sortKey="Pauls, David L" sort="Pauls, David L" uniqKey="Pauls D" first="David L" last="Pauls">David L. Pauls</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital</wicri:orgArea></affiliation></author><author><name sortKey="Wang, Kai" sort="Wang, Kai" uniqKey="Wang K" first="Kai" last="Wang">Kai Wang</name><affiliation wicri:level="3"><nlm:affiliation>Zilkha Neurogenetic Institute, Los Angeles.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName><wicri:orgArea>Zilkha Neurogenetic Institute</wicri:orgArea></affiliation></author><author><name sortKey="Scharf, Jeremiah M" sort="Scharf, Jeremiah M" uniqKey="Scharf J" first="Jeremiah M" last="Scharf">Jeremiah M. Scharf</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital, Boston; Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute, Boston. Electronic address: jscharf@partners.org.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital, Boston; Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute</wicri:orgArea></affiliation></author></analytic><series><title level="j">Journal of the American Academy of Child and Adolescent Psychiatry</title><idno type="eISSN">1527-5418</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>DNA Copy Number Variations</term><term>Diagnostic and Statistical Manual of Mental Disorders</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Humans</term><term>Male</term><term>Obsessive-Compulsive Disorder (diagnosis)</term><term>Obsessive-Compulsive Disorder (genetics)</term><term>Polymorphism, Single Nucleotide</term><term>Tourette Syndrome (diagnosis)</term><term>Tourette Syndrome (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Diagnostic and stastistical manual of mental disorders (USA)</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Polymorphisme de nucléotide simple</term><term>Prédisposition génétique à une maladie</term><term>Syndrome de Tourette (diagnostic)</term><term>Syndrome de Tourette (génétique)</term><term>Trouble obsessionnel compulsif (diagnostic)</term><term>Trouble obsessionnel compulsif (génétique)</term><term>Variations de nombre de copies de segment d'ADN</term><term>Étude d'association pangénomique</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Obsessive-Compulsive Disorder</term><term>Tourette Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Syndrome de Tourette</term><term>Trouble obsessionnel compulsif</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Obsessive-Compulsive Disorder</term><term>Tourette Syndrome</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Syndrome de Tourette</term><term>Trouble obsessionnel compulsif</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>DNA Copy Number Variations</term><term>Diagnostic and Statistical Manual of Mental Disorders</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Humans</term><term>Male</term><term>Polymorphism, Single Nucleotide</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Diagnostic and stastistical manual of mental disorders (USA)</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Polymorphisme de nucléotide simple</term><term>Prédisposition génétique à une maladie</term><term>Variations de nombre de copies de segment d'ADN</term><term>Étude d'association pangénomique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) are heritable neurodevelopmental disorders with a partially shared genetic etiology. This study represents the first genome-wide investigation of large (>500 kb), rare (<1%) copy number variants (CNVs) in OCD and the largest genome-wide CNV analysis in TS to date.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25062598</PMID><DateCreated><Year>2014</Year><Month>07</Month><Day>26</Day></DateCreated><DateCompleted><Year>2015</Year><Month>10</Month><Day>13</Day></DateCompleted><DateRevised><Year>2017</Year><Month>03</Month><Day>03</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1527-5418</ISSN><JournalIssue CitedMedium="Internet"><Volume>53</Volume><Issue>8</Issue><PubDate><Year>2014</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Journal of the American Academy of Child and Adolescent Psychiatry</Title><ISOAbbreviation>J Am Acad Child Adolesc Psychiatry</ISOAbbreviation></Journal><ArticleTitle>Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.</ArticleTitle><Pagination><MedlinePgn>910-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jaac.2014.04.022</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0890-8567(14)00404-3</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) are heritable neurodevelopmental disorders with a partially shared genetic etiology. This study represents the first genome-wide investigation of large (>500 kb), rare (<1%) copy number variants (CNVs) in OCD and the largest genome-wide CNV analysis in TS to date.</AbstractText><AbstractText Label="METHOD" NlmCategory="METHODS">The primary analyses used a cross-disorder design for 2,699 case patients (1,613 ascertained for OCD, 1,086 ascertained for TS) and 1,789 controls. Parental data facilitated a de novo analysis in 348 OCD trios.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Although no global CNV burden was detected in the cross-disorder analysis or in secondary, disease-specific analyses, there was a 3.3-fold increased burden of large deletions previously associated with other neurodevelopmental disorders (p = .09). Half of these neurodevelopmental deletions were located in a single locus, 16p13.11 (5 case patient deletions: 0 control deletions, p = .08 in the current study, p = .025 compared to published controls). Three 16p13.11 deletions were confirmed de novo, providing further support for the etiological significance of this region. The overall OCD de novo rate was 1.4%, which is intermediate between published rates in controls (0.7%) and in individuals with autism or schizophrenia (2-4%).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Several converging lines of evidence implicate 16p13.11 deletions in OCD, with weaker evidence for a role in TS. The trend toward increased overall neurodevelopmental CNV burden in TS and OCD suggests that deletions previously associated with other neurodevelopmental disorders may also contribute to these phenotypes.</AbstractText><CopyrightInformation>Copyright © 2014 American Academy of Child and Adolescent Psychiatry. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>McGrath</LastName><ForeName>Lauren M</ForeName><Initials>LM</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston; American University, Washington, DC; Harvard-MIT Broad Institute, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yu</LastName><ForeName>Dongmei</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marshall</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davis</LastName><ForeName>Lea K</ForeName><Initials>LK</Initials><AffiliationInfo><Affiliation>University of Chicago.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thiruvahindrapuram</LastName><ForeName>Bhooma</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Bingbin</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cappi</LastName><ForeName>Carolina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>University of São Paulo Medical School.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gerber</LastName><ForeName>Gloria</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wolf</LastName><ForeName>Aaron</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schroeder</LastName><ForeName>Frederick A</ForeName><Initials>FA</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Osiecki</LastName><ForeName>Lisa</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Dushlaine</LastName><ForeName>Colm</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Harvard-MIT Broad Institute, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kirby</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Illmann</LastName><ForeName>Cornelia</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haddad</LastName><ForeName>Stephen</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gallagher</LastName><ForeName>Patience</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fagerness</LastName><ForeName>Jesen A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barr</LastName><ForeName>Cathy L</ForeName><Initials>CL</Initials><AffiliationInfo><Affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Toronto Western Research Institute, University Health Network, Toronto.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bellodi</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Università Vita-Salute San Raffaele, Milan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benarroch</LastName><ForeName>Fortu</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Hadassah-Hebrew University Medical Center, Jerusalem.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bienvenu</LastName><ForeName>O Joseph</ForeName><Initials>OJ</Initials><AffiliationInfo><Affiliation>Johns Hopkins University School of Medicine, Baltimore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Black</LastName><ForeName>Donald W</ForeName><Initials>DW</Initials><AffiliationInfo><Affiliation>University of Iowa College of Medicine, Iowa City.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bloch</LastName><ForeName>Michael H</ForeName><Initials>MH</Initials><AffiliationInfo><Affiliation>Yale University School of Medicine, New Haven, CT.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bruun</LastName><ForeName>Ruth D</ForeName><Initials>RD</Initials><AffiliationInfo><Affiliation>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; New York University Medical Center, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Budman</LastName><ForeName>Cathy L</ForeName><Initials>CL</Initials><AffiliationInfo><Affiliation>North Shore-Long Island Jewish Medical Center, New Hyde Park, NY; Hofstra University School of Medicine, Hempstead, NY.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Camarena</LastName><ForeName>Beatriz</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Instituto Nacional de Psiquiatría Ramon de la Fuente Muñiz, Mexico.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cath</LastName><ForeName>Danielle C</ForeName><Initials>DC</Initials><AffiliationInfo><Affiliation>Utrecht University and VU Medical Center, Amsterdam.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cavallini</LastName><ForeName>Maria C</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Ospedale San Raffaele, Milan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chouinard</LastName><ForeName>Sylvain</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>University of Montreal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Coric</LastName><ForeName>Vladimir</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Yale University School of Medicine, New Haven, CT.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cullen</LastName><ForeName>Bernadette</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Johns Hopkins University School of Medicine, Baltimore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Delorme</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Robert Debre University Hospital, Paris and the French National Science Foundation, Creteil, France; 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Harvard-MIT Broad Institute, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nurmi</LastName><ForeName>Erika</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>University of California, Los Angeles (UCLA) School of Medicine.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pakstis</LastName><ForeName>Andrew J</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>Yale University School of Medicine, New Haven, CT.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pato</LastName><ForeName>Michele T</ForeName><Initials>MT</Initials><AffiliationInfo><Affiliation>Zilkha Neurogenetic Institute, Los Angeles.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pato</LastName><ForeName>Carlos N</ForeName><Initials>CN</Initials><AffiliationInfo><Affiliation>Zilkha Neurogenetic Institute, Los Angeles.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Piacentini</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>University of California, Los Angeles (UCLA) School of Medicine.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pittenger</LastName><ForeName>Christopher</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Yale University School of Medicine, New Haven, CT.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pollak</LastName><ForeName>Yehuda</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Shaare Zedek Medical Center, Jerusalem.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Reus</LastName><ForeName>Victor I</ForeName><Initials>VI</Initials><AffiliationInfo><Affiliation>University of California at San Francisco School of Medicine.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Richter</LastName><ForeName>Margaret A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>University of Toronto and the Hospital for Sick Children, Toronto; Sunnybrook Health Sciences Centre, Toronto.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Riddle</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Johns Hopkins University School of Medicine, Baltimore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Robertson</LastName><ForeName>Mary M</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>University College London.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rosenberg</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Wayne State University and Detroit Medical Center, Detroit.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rouleau</LastName><ForeName>Guy A</ForeName><Initials>GA</Initials><AffiliationInfo><Affiliation>Montreal Neurological Institute.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ruhrmann</LastName><ForeName>Stephan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>University of Cologne, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sampaio</LastName><ForeName>Aline S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Federal University of São Paulo; 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Semel Institute for Neuroscience and Human Behavior, UCLA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Petryshen</LastName><ForeName>Tracey</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston; Harvard-MIT Broad Institute, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Posthuma</LastName><ForeName>Danielle</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>VU Amsterdam and Erasmus University Medical Centre, Rotterdam.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jenike</LastName><ForeName>Michael A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cox</LastName><ForeName>Nancy J</ForeName><Initials>NJ</Initials><AffiliationInfo><Affiliation>University of Chicago.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hanna</LastName><ForeName>Gregory L</ForeName><Initials>GL</Initials><AffiliationInfo><Affiliation>University of Michigan, Ann Arbor, MI.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brentani</LastName><ForeName>Helena</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>University of São Paulo Medical School.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scherer</LastName><ForeName>Stephen W</ForeName><Initials>SW</Initials><AffiliationInfo><Affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arnold</LastName><ForeName>Paul D</ForeName><Initials>PD</Initials><AffiliationInfo><Affiliation>University of Toronto and the Hospital for Sick Children, Toronto.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stewart</LastName><ForeName>S Evelyn</ForeName><Initials>SE</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital, Boston; 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Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute, Boston. Electronic address: jscharf@partners.org.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>UL1 TR000430</GrantID><Acronym>TR</Acronym><Agency>NCATS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>K23MH085057</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01NS40024</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MH073250</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01HG004438</GrantID><Acronym>HG</Acronym><Agency>NHGRI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 HG004438</GrantID><Acronym>HG</Acronym><Agency>NHGRI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>T32MH16259</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH 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States</Country></Grant><Grant><GrantID>T32 MH018268</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P30NS062691</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>HHSN268200782096C</GrantID><Acronym>HG</Acronym><Agency>NHGRI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 MH079489</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 MH085321</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01MH092293</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 HG004422</GrantID><Acronym>HG</Acronym><Agency>NHGRI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 DA013423</GrantID><Acronym>DA</Acronym><Agency>NIDA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 NS040024</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U24 MH068457</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>UL1 TR000142</GrantID><Acronym>TR</Acronym><Agency>NCATS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 MH058376</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 MH092293</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U10 AA008401</GrantID><Acronym>AA</Acronym><Agency>NIAAA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>HHSN268200782096C</GrantID><Agency>PHS HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>T32 MH016259</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01NS16648</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>K23 MH094613</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01MH079489</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 NS037484</GrantID><Acronym>NS</Acronym><Agency>NINDS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R13 MH073250</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>K20MH01065</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D057666">Research Support, American Recovery and Reinvestment Act</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>06</Month><Day>24</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Am Acad Child Adolesc Psychiatry</MedlineTA><NlmUniqueID>8704565</NlmUniqueID><ISSNLinking>0890-8567</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Mol Psychiatry. 2013 Jul;18(7):788-98</RefSource><PMID Version="1">22889921</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuron. 2011 Dec 22;72(6):951-63</RefSource><PMID 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Version="1">20888040</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D056915" MajorTopicYN="Y">DNA Copy Number Variations</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D039721" MajorTopicYN="N">Diagnostic and Statistical Manual of Mental Disorders</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020022" MajorTopicYN="N">Genetic Predisposition to Disease</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055106" MajorTopicYN="N">Genome-Wide Association Study</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009771" MajorTopicYN="N">Obsessive-Compulsive Disorder</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020641" MajorTopicYN="N">Polymorphism, Single Nucleotide</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005879" MajorTopicYN="N">Tourette Syndrome</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading></MeshHeadingList><OtherID Source="NLM">NIHMS608519</OtherID><OtherID Source="NLM">PMC4218748</OtherID><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">16p13.11</Keyword><Keyword MajorTopicYN="N">Tourette syndrome</Keyword><Keyword MajorTopicYN="N">copy number variation</Keyword><Keyword MajorTopicYN="N">genetics</Keyword><Keyword MajorTopicYN="N">obsessive-compulsive disorder</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>12</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2014</Year><Month>03</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>06</Month><Day>18</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>7</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>7</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>10</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25062598</ArticleId><ArticleId 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