High-grade atrioventricular block in acute coronary syndromes: insights from the Global Registry of Acute Coronary Events.
Identifieur interne : 002E20 ( PubMed/Curation ); précédent : 002E19; suivant : 002E21High-grade atrioventricular block in acute coronary syndromes: insights from the Global Registry of Acute Coronary Events.
Auteurs : Sheldon M. Singh [Canada] ; Gordon Fitzgerald [États-Unis] ; Andrew T. Yan [Canada] ; David Brieger [Australie] ; Keith A A. Fox [Royaume-Uni] ; Jose L Pez-Send N [Espagne] ; Raymond T. Yan [Canada] ; Kim A. Eagle [États-Unis] ; Ph Gabriel Steg [France] ; Andrzej Budaj [Pologne] ; Shaun G. Goodman [Canada]Source :
- European heart journal [ 1522-9645 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Bloc atrioventriculaire (), Bloc atrioventriculaire (mortalité), Enregistrements, Femelle, Hospitalisation (), Humains, Infarctus du myocarde (), Infarctus du myocarde (mortalité), Intervention coronarienne percutanée (mortalité), Mortalité hospitalière, Mâle, Pacemaker (), Pronostic, Sujet âgé, Syndrome coronarien aigu (), Syndrome coronarien aigu (mortalité), Études prospectives.
- MESH :
- mortalité : Bloc atrioventriculaire, Infarctus du myocarde, Intervention coronarienne percutanée, Syndrome coronarien aigu.
- Adulte d'âge moyen, Bloc atrioventriculaire, Enregistrements, Femelle, Hospitalisation, Humains, Infarctus du myocarde, Mortalité hospitalière, Mâle, Pacemaker, Pronostic, Sujet âgé, Syndrome coronarien aigu, Études prospectives.
English descriptors
- KwdEn :
- Acute Coronary Syndrome (complications), Acute Coronary Syndrome (mortality), Aged, Atrioventricular Block (complications), Atrioventricular Block (mortality), Female, Hospital Mortality, Hospitalization (statistics & numerical data), Humans, Male, Middle Aged, Myocardial Infarction (complications), Myocardial Infarction (mortality), Pacemaker, Artificial (statistics & numerical data), Percutaneous Coronary Intervention (mortality), Prognosis, Prospective Studies, Registries.
- MESH :
- complications : Acute Coronary Syndrome, Atrioventricular Block, Myocardial Infarction.
- mortality : Acute Coronary Syndrome, Atrioventricular Block, Myocardial Infarction, Percutaneous Coronary Intervention.
- statistics & numerical data : Hospitalization, Pacemaker, Artificial.
- Aged, Female, Hospital Mortality, Humans, Male, Middle Aged, Prognosis, Prospective Studies, Registries.
Abstract
While prior work has suggested that a high-grade atrioventricular block (HAVB) in the setting of an acute coronary syndrome (ACS) is associated with in-hospital death, limited information is available on the incidence of, and death associated with, HAVB in ACS patients receiving contemporary management.
DOI: 10.1093/eurheartj/ehu357
PubMed: 25205530
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Singh</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiology, Department of Medicine, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Cardiology, Department of Medicine, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Fitzgerald, Gordon" sort="Fitzgerald, Gordon" uniqKey="Fitzgerald G" first="Gordon" last="Fitzgerald">Gordon Fitzgerald</name><affiliation wicri:level="1"><nlm:affiliation>Center for Outcomes Research, University of Massachusetts Medical School, Worcester, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Outcomes Research, University of Massachusetts Medical School, Worcester, MA</wicri:regionArea></affiliation></author><author><name sortKey="Yan, Andrew T" sort="Yan, Andrew T" uniqKey="Yan A" first="Andrew T" last="Yan">Andrew T. 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Goodman</name><affiliation wicri:level="1"><nlm:affiliation>Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Canada Canadian Heart Research Centre, Toronto, Canada Division of Cardiology, St Michael's Hospital, 30 Bond Street, Room 6-034 Queen, Toronto, Ontario, Canada M5B 1W8 goodmans@smh.ca.</nlm:affiliation><country wicri:rule="url">Canada</country><wicri:regionArea>Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Canada Canadian Heart Research Centre, Toronto, Canada Division of Cardiology, St Michael's Hospital, 30 Bond Street, Room 6-034 Queen, Toronto, Ontario</wicri:regionArea></affiliation></author></analytic><series><title level="j">European heart journal</title><idno type="eISSN">1522-9645</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute Coronary Syndrome (complications)</term><term>Acute Coronary Syndrome (mortality)</term><term>Aged</term><term>Atrioventricular Block (complications)</term><term>Atrioventricular Block (mortality)</term><term>Female</term><term>Hospital Mortality</term><term>Hospitalization (statistics & numerical data)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Myocardial Infarction (complications)</term><term>Myocardial Infarction (mortality)</term><term>Pacemaker, Artificial (statistics & numerical data)</term><term>Percutaneous Coronary Intervention (mortality)</term><term>Prognosis</term><term>Prospective Studies</term><term>Registries</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Bloc atrioventriculaire ()</term><term>Bloc atrioventriculaire (mortalité)</term><term>Enregistrements</term><term>Femelle</term><term>Hospitalisation ()</term><term>Humains</term><term>Infarctus du myocarde ()</term><term>Infarctus du myocarde (mortalité)</term><term>Intervention coronarienne percutanée (mortalité)</term><term>Mortalité hospitalière</term><term>Mâle</term><term>Pacemaker ()</term><term>Pronostic</term><term>Sujet âgé</term><term>Syndrome coronarien aigu ()</term><term>Syndrome coronarien aigu (mortalité)</term><term>Études prospectives</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Acute Coronary Syndrome</term><term>Atrioventricular Block</term><term>Myocardial Infarction</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Acute Coronary Syndrome</term><term>Atrioventricular Block</term><term>Myocardial Infarction</term><term>Percutaneous Coronary Intervention</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Bloc atrioventriculaire</term><term>Infarctus du myocarde</term><term>Intervention coronarienne percutanée</term><term>Syndrome coronarien aigu</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term><term>Pacemaker, Artificial</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Hospital Mortality</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prognosis</term><term>Prospective Studies</term><term>Registries</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Bloc atrioventriculaire</term><term>Enregistrements</term><term>Femelle</term><term>Hospitalisation</term><term>Humains</term><term>Infarctus du myocarde</term><term>Mortalité hospitalière</term><term>Mâle</term><term>Pacemaker</term><term>Pronostic</term><term>Sujet âgé</term><term>Syndrome coronarien aigu</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">While prior work has suggested that a high-grade atrioventricular block (HAVB) in the setting of an acute coronary syndrome (ACS) is associated with in-hospital death, limited information is available on the incidence of, and death associated with, HAVB in ACS patients receiving contemporary management.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25205530</PMID><DateCreated><Year>2015</Year><Month>04</Month><Day>22</Day></DateCreated><DateCompleted><Year>2016</Year><Month>01</Month><Day>26</Day></DateCompleted><DateRevised><Year>2015</Year><Month>04</Month><Day>22</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1522-9645</ISSN><JournalIssue CitedMedium="Internet"><Volume>36</Volume><Issue>16</Issue><PubDate><Year>2015</Year><Month>Apr</Month><Day>21</Day></PubDate></JournalIssue><Title>European heart journal</Title><ISOAbbreviation>Eur. Heart J.</ISOAbbreviation></Journal><ArticleTitle>High-grade atrioventricular block in acute coronary syndromes: insights from the Global Registry of Acute Coronary Events.</ArticleTitle><Pagination><MedlinePgn>976-83</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/eurheartj/ehu357</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">While prior work has suggested that a high-grade atrioventricular block (HAVB) in the setting of an acute coronary syndrome (ACS) is associated with in-hospital death, limited information is available on the incidence of, and death associated with, HAVB in ACS patients receiving contemporary management.</AbstractText><AbstractText Label="METHODS AND RESULTS" NlmCategory="RESULTS">The incidence of HAVB was determined within The Global Registry of Acute Coronary Events (GRACE). The clinical characteristics, in-hospital therapies, and outcomes were compared between patients with and without HAVB. Factors associated with death in patients with HAVB were determined. A total of 59 229 patients with ACS between 1999 and 2007 were identified; 2.9% of patients had HAVB at any point during the index hospitalization; 22.7% of whom died in hospital [adjusted odds ratio (OR) = 4.2, 95% confidence interval (CI), 3.6-4.9, P < 0.001]. The association between HAVB and in-hospital death varied with type of ACS [OR: ST-segment elevation myocardial infarction (STEMI) = 3.0; non-STEMI = 6.4; unstable angina = 8.2, P for interaction < 0.001]. High-grade atrioventricular block present at the time of presentation to hospital (vs. occurring in-hospital) and early (<12 h) percutaneous coronary intervention or fibrinolysis (vs.>12 h or no intervention) were associated with improved in-hospital survival, whereas temporary pacemaker insertion was not. Patients with HAVB surviving to discharge had similar adjusted survival at 6 months compared with those without HAVB. A reduction in the rate of, but not in-hospital mortality associated with, HAVB was noted over the study period.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Although the incidence of HAVB is low and decreasing, this complication continues to have a high risk of in-hospital death.</AbstractText><CopyrightInformation>Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Singh</LastName><ForeName>Sheldon M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Division of Cardiology, Department of Medicine, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>FitzGerald</LastName><ForeName>Gordon</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Center for Outcomes Research, University of Massachusetts Medical School, Worcester, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yan</LastName><ForeName>Andrew T</ForeName><Initials>AT</Initials><AffiliationInfo><Affiliation>Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brieger</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Coronary Care Unit, Concord Hospital, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>Keith A A</ForeName><Initials>KA</Initials><AffiliationInfo><Affiliation>Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>López-Sendón</LastName><ForeName>Jose</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Hospital Universitario La Paz, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yan</LastName><ForeName>Raymond T</ForeName><Initials>RT</Initials><AffiliationInfo><Affiliation>University of Toronto, Toronto, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eagle</LastName><ForeName>Kim A</ForeName><Initials>KA</Initials><AffiliationInfo><Affiliation>University of Michigan Medical Center, Ann Arbor, MI, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steg</LastName><ForeName>Ph Gabriel</ForeName><Initials>PG</Initials><AffiliationInfo><Affiliation>Hôpital Bichat, Assistance Publique, Hôpitaux de Paris, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Budaj</LastName><ForeName>Andrzej</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Grochowski Hospital, Warsaw, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goodman</LastName><ForeName>Shaun G</ForeName><Initials>SG</Initials><AffiliationInfo><Affiliation>Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Canada Canadian Heart Research Centre, Toronto, Canada Division of Cardiology, St Michael's Hospital, 30 Bond Street, Room 6-034 Queen, Toronto, Ontario, Canada M5B 1W8 goodmans@smh.ca.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType><PublicationType UI="D064888">Observational Study</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>09</Month><Day>08</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Eur Heart J</MedlineTA><NlmUniqueID>8006263</NlmUniqueID><ISSNLinking>0195-668X</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D054058" MajorTopicYN="N">Acute Coronary Syndrome</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D054537" MajorTopicYN="N">Atrioventricular Block</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017052" MajorTopicYN="N">Hospital Mortality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009203" MajorTopicYN="N">Myocardial Infarction</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010138" MajorTopicYN="N">Pacemaker, Artificial</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D062645" MajorTopicYN="N">Percutaneous Coronary Intervention</DescriptorName><QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012042" MajorTopicYN="N">Registries</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Acute coronary syndromes</Keyword><Keyword MajorTopicYN="N">Artificial pacemaker</Keyword><Keyword MajorTopicYN="N">Atrioventricular block</Keyword><Keyword MajorTopicYN="N">Percutaneous coronary intervention</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>01</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>08</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>9</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>9</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>1</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25205530</ArticleId><ArticleId IdType="pii">ehu357</ArticleId><ArticleId IdType="doi">10.1093/eurheartj/ehu357</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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