Prospective study into the value of the automated Elecsys antimüllerian hormone assay for the assessment of the ovarian growing follicle pool.
Identifieur interne : 002E10 ( PubMed/Curation ); précédent : 002E09; suivant : 002E11Prospective study into the value of the automated Elecsys antimüllerian hormone assay for the assessment of the ovarian growing follicle pool.
Auteurs : Richard A. Anderson [Royaume-Uni] ; Ellen Anckaert [Belgique] ; Ernesto Bosch [Espagne] ; Didier Dewailly [France] ; Cheryl E. Dunlop [Royaume-Uni] ; Daniel Fehr [Allemagne] ; Luciano Nardo [Royaume-Uni] ; Johan Smitz [Belgique] ; Kelton Tremellen [Australie] ; Barbara Denk [Allemagne] ; Andrea Geistanger [Allemagne] ; Martin Hund [Suisse]Source :
- Fertility and sterility [ 1556-5653 ] ; 2015.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Analyse chimique du sang (), Analyse chimique du sang (instrumentation), Femelle, Follicule ovarique (cytologie), Follicule ovarique (physiologie), Hormone antimullérienne (sang), Humains, Induction d'ovulation, Infertilité féminine (), Infertilité féminine (diagnostic), Infertilité féminine (sang), Jeune adulte, Laboratoire automatique, Numération cellulaire, Pronostic, Réserve ovarienne, Valeur prédictive des tests.
- MESH :
- cytologie : Follicule ovarique.
- diagnostic : Infertilité féminine.
- physiologie : Follicule ovarique.
- sang : Analyse chimique du sang, Hormone antimullérienne, Infertilité féminine.
- Adolescent, Adulte, Analyse chimique du sang, Femelle, Humains, Induction d'ovulation, Infertilité féminine, Jeune adulte, Laboratoire automatique, Numération cellulaire, Pronostic, Réserve ovarienne, Valeur prédictive des tests.
English descriptors
- KwdEn :
- Adolescent, Adult, Anti-Mullerian Hormone (blood), Automation, Laboratory, Blood Chemical Analysis (instrumentation), Blood Chemical Analysis (methods), Cell Count, Female, Humans, Infertility, Female (blood), Infertility, Female (diagnosis), Infertility, Female (therapy), Ovarian Follicle (cytology), Ovarian Follicle (physiology), Ovarian Reserve, Ovulation Induction, Predictive Value of Tests, Prognosis, Young Adult.
- MESH :
- chemical , blood : Anti-Mullerian Hormone.
- blood : Infertility, Female.
- cytology : Ovarian Follicle.
- diagnosis : Infertility, Female.
- instrumentation : Blood Chemical Analysis.
- methods : Blood Chemical Analysis.
- physiology : Ovarian Follicle.
- therapy : Infertility, Female.
- Adolescent, Adult, Automation, Laboratory, Cell Count, Female, Humans, Ovarian Reserve, Ovulation Induction, Predictive Value of Tests, Prognosis, Young Adult.
Abstract
To evaluate a new fully automated assay measuring antimüllerian hormone (AMH; Roche Elecsys) against antral follicle count in women of reproductive age.
DOI: 10.1016/j.fertnstert.2015.01.004
PubMed: 25681853
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Health Group, Manchester, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>GyneHealth Reproductive Health Group, Manchester</wicri:regionArea></affiliation></author><author><name sortKey="Smitz, Johan" sort="Smitz, Johan" uniqKey="Smitz J" first="Johan" last="Smitz">Johan Smitz</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Hormonology and Tumour Markers, Universitair Ziekenhuis Brussel, Free University of Brussels (VUB), Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Hormonology and Tumour Markers, Universitair Ziekenhuis Brussel, Free University of Brussels (VUB), Brussels</wicri:regionArea></affiliation></author><author><name sortKey="Tremellen, Kelton" sort="Tremellen, Kelton" uniqKey="Tremellen K" first="Kelton" last="Tremellen">Kelton Tremellen</name><affiliation wicri:level="1"><nlm:affiliation>Repromed, Dulwich, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Repromed, Dulwich</wicri:regionArea></affiliation></author><author><name sortKey="Denk, Barbara" sort="Denk, Barbara" uniqKey="Denk B" first="Barbara" last="Denk">Barbara Denk</name><affiliation wicri:level="1"><nlm:affiliation>Roche Diagnostics GmbH, Penzberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Roche Diagnostics GmbH, Penzberg</wicri:regionArea></affiliation></author><author><name sortKey="Geistanger, Andrea" sort="Geistanger, Andrea" uniqKey="Geistanger A" first="Andrea" last="Geistanger">Andrea Geistanger</name><affiliation wicri:level="1"><nlm:affiliation>Roche Diagnostics GmbH, Penzberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Roche Diagnostics GmbH, Penzberg</wicri:regionArea></affiliation></author><author><name sortKey="Hund, Martin" sort="Hund, Martin" uniqKey="Hund M" first="Martin" last="Hund">Martin Hund</name><affiliation wicri:level="1"><nlm:affiliation>Roche Diagnostics International Ltd., Rotkreuz, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Roche Diagnostics International Ltd., Rotkreuz</wicri:regionArea></affiliation></author></analytic><series><title level="j">Fertility and sterility</title><idno type="eISSN">1556-5653</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Anti-Mullerian Hormone (blood)</term><term>Automation, Laboratory</term><term>Blood Chemical Analysis (instrumentation)</term><term>Blood Chemical Analysis (methods)</term><term>Cell Count</term><term>Female</term><term>Humans</term><term>Infertility, Female (blood)</term><term>Infertility, Female (diagnosis)</term><term>Infertility, Female (therapy)</term><term>Ovarian Follicle (cytology)</term><term>Ovarian Follicle (physiology)</term><term>Ovarian Reserve</term><term>Ovulation Induction</term><term>Predictive Value of Tests</term><term>Prognosis</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Analyse chimique du sang ()</term><term>Analyse chimique du sang (instrumentation)</term><term>Femelle</term><term>Follicule ovarique (cytologie)</term><term>Follicule ovarique (physiologie)</term><term>Hormone antimullérienne (sang)</term><term>Humains</term><term>Induction d'ovulation</term><term>Infertilité féminine ()</term><term>Infertilité féminine (diagnostic)</term><term>Infertilité féminine (sang)</term><term>Jeune adulte</term><term>Laboratoire automatique</term><term>Numération cellulaire</term><term>Pronostic</term><term>Réserve ovarienne</term><term>Valeur prédictive des tests</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Anti-Mullerian Hormone</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Infertility, Female</term></keywords><keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Follicule ovarique</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Ovarian Follicle</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Infertility, Female</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infertilité féminine</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Blood Chemical Analysis</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Blood Chemical Analysis</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Follicule ovarique</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Ovarian Follicle</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Analyse chimique du sang</term><term>Hormone antimullérienne</term><term>Infertilité féminine</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Infertility, Female</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Automation, Laboratory</term><term>Cell Count</term><term>Female</term><term>Humans</term><term>Ovarian Reserve</term><term>Ovulation Induction</term><term>Predictive Value of Tests</term><term>Prognosis</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Analyse chimique du sang</term><term>Femelle</term><term>Humains</term><term>Induction d'ovulation</term><term>Infertilité féminine</term><term>Jeune adulte</term><term>Laboratoire automatique</term><term>Numération cellulaire</term><term>Pronostic</term><term>Réserve ovarienne</term><term>Valeur prédictive des tests</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To evaluate a new fully automated assay measuring antimüllerian hormone (AMH; Roche Elecsys) against antral follicle count in women of reproductive age.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25681853</PMID><DateCreated><Year>2015</Year><Month>04</Month><Day>03</Day></DateCreated><DateCompleted><Year>2015</Year><Month>06</Month><Day>12</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1556-5653</ISSN><JournalIssue CitedMedium="Internet"><Volume>103</Volume><Issue>4</Issue><PubDate><Year>2015</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Fertility and sterility</Title><ISOAbbreviation>Fertil. Steril.</ISOAbbreviation></Journal><ArticleTitle>Prospective study into the value of the automated Elecsys antimüllerian hormone assay for the assessment of the ovarian growing follicle pool.</ArticleTitle><Pagination><MedlinePgn>1074-1080.e4</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.fertnstert.2015.01.004</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0015-0282(15)00039-4</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate a new fully automated assay measuring antimüllerian hormone (AMH; Roche Elecsys) against antral follicle count in women of reproductive age.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">Prospective cohort study.</AbstractText><AbstractText Label="SETTING" NlmCategory="METHODS">Hospital infertility clinics and academic centers.</AbstractText><AbstractText Label="PATIENT(S)" NlmCategory="METHODS">Four hundred fifty-one women aged 18 to 44 years, with regular menstrual cycles.</AbstractText><AbstractText Label="INTERVENTION(S)" NlmCategory="METHODS">None.</AbstractText><AbstractText Label="MAIN OUTCOME MEASURE(S)" NlmCategory="METHODS">AMH and antral follicle count (AFC) determined at a single visit on day 2-4 of the menstrual cycle.</AbstractText><AbstractText Label="RESULT(S)" NlmCategory="RESULTS">There was a statistically significant variance in AFC but not in AMH between centers. Both AFC and AMH varied by age (overall Spearman rho -0.50 for AFC and -0.47 for AMH), but there was also significant between-center variation in the relationship between AFC and age but not for AMH. There was a strong positive correlation between AMH and AFC (overall spearman rho 0.68), which varied from 0.49 to 0.87 between centers. An agreement table using AFC cutoffs of 7 and 15 showed classification agreement in 63.2%, 56.9% and 74.5% of women for low, medium, and high groups, respectively.</AbstractText><AbstractText Label="CONCLUSION(S)" NlmCategory="CONCLUSIONS">The novel fully automated Elecsys AMH assay shows good correlations with age and AFC in women of reproductive age, providing a reproducible measure of the growing follicle pool.</AbstractText><CopyrightInformation>Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Anderson</LastName><ForeName>Richard A</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>MRC Centre for Reproductive Health, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom. Electronic address: richard.anderson@ed.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anckaert</LastName><ForeName>Ellen</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Laboratory of Hormonology and Tumour Markers, Universitair Ziekenhuis Brussel, Free University of Brussels (VUB), Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bosch</LastName><ForeName>Ernesto</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>IVI Valencia, Valencia, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dewailly</LastName><ForeName>Didier</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Endocrine Gynaecology and Reproductive Medicine, Hôpital Jeanne de Flandre, Centre Hospitalier de Lille, Université Lille 2, Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dunlop</LastName><ForeName>Cheryl E</ForeName><Initials>CE</Initials><AffiliationInfo><Affiliation>MRC Centre for Reproductive Health, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fehr</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>UniKiD, Univ.-Frauenklinik Düsseldorf, Düsseldorf, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nardo</LastName><ForeName>Luciano</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>GyneHealth Reproductive Health Group, Manchester, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smitz</LastName><ForeName>Johan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Laboratory of Hormonology and Tumour Markers, Universitair Ziekenhuis Brussel, Free University of Brussels (VUB), Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tremellen</LastName><ForeName>Kelton</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Repromed, Dulwich, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Denk</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Roche Diagnostics GmbH, Penzberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Geistanger</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Roche Diagnostics GmbH, Penzberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hund</LastName><ForeName>Martin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Roche Diagnostics International Ltd., Rotkreuz, Switzerland.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>G1100356</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/K50094X/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D023362">Evaluation Studies</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D064888">Observational Study</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>02</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Fertil Steril</MedlineTA><NlmUniqueID>0372772</NlmUniqueID><ISSNLinking>0015-0282</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>80497-65-0</RegistryNumber><NameOfSubstance UI="D054304">Anti-Mullerian Hormone</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D054304" MajorTopicYN="N">Anti-Mullerian Hormone</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D057205" MajorTopicYN="N">Automation, Laboratory</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001774" MajorTopicYN="N">Blood Chemical Analysis</DescriptorName><QualifierName UI="Q000295" MajorTopicYN="N">instrumentation</QualifierName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002452" MajorTopicYN="N">Cell Count</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007247" MajorTopicYN="N">Infertility, Female</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006080" MajorTopicYN="N">Ovarian Follicle</DescriptorName><QualifierName UI="Q000166" MajorTopicYN="Y">cytology</QualifierName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D065851" MajorTopicYN="N">Ovarian Reserve</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010062" MajorTopicYN="Y">Ovulation Induction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Antimüllerian hormone</Keyword><Keyword MajorTopicYN="N">antral follicle count</Keyword><Keyword MajorTopicYN="N">ovarian follicle</Keyword><Keyword MajorTopicYN="N">ovarian reserve</Keyword><Keyword MajorTopicYN="N">reproductive life span</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>10</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2014</Year><Month>12</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>01</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>2</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>2</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>6</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25681853</ArticleId><ArticleId IdType="pii">S0015-0282(15)00039-4</ArticleId><ArticleId IdType="doi">10.1016/j.fertnstert.2015.01.004</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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