Cerebrovascular events in inflammatory bowel disease patients treated with anti-tumour necrosis factor alpha agents.
Identifieur interne : 002D32 ( PubMed/Curation ); précédent : 002D31; suivant : 002D33Cerebrovascular events in inflammatory bowel disease patients treated with anti-tumour necrosis factor alpha agents.
Auteurs : Konstantinos Karmiris [Oman] ; Peter Bossuyt [Belgique] ; Dario Sorrentino [Italie] ; Tom Moreels [Belgique] ; Antonella Scarcelli [Italie] ; Jesus Legido [Espagne] ; Iris Dotan [Israël] ; Graham D. Naismith [Royaume-Uni] ; Airi Jussila [Finlande] ; Jan C. Preiss [Allemagne] ; Wolfgang Kruis [Allemagne] ; Andy C Y. Li [Royaume-Uni] ; Guillaume Bouguen [France] ; Henit Yanai [Espagne] ; Flavio Steinwurz [Brésil] ; Konstantinos H. Katsanos [Grèce] ; Kavitha Subramaniam [Australie] ; Dino Tarabar [Serbie] ; Ioannis V. Zaganas [Grèce] ; Shomron Ben-Horin [Israël]Source :
- Journal of Crohn's & colitis [ 1876-4479 ] ; 2015.
Descripteurs français
- KwdFr :
- Adalimumab (usage thérapeutique), Adulte, Adulte d'âge moyen, Angiopathies intracrâniennes (diagnostic), Angiopathies intracrâniennes (étiologie), Anti-inflammatoires non stéroïdiens (usage thérapeutique), Association de médicaments, Azathioprine (usage thérapeutique), Certolizumab pégol (usage thérapeutique), Facteur de nécrose tumorale alpha (antagonistes et inhibiteurs), Femelle, Humains, Immunosuppresseurs (usage thérapeutique), Infliximab (usage thérapeutique), Jeune adulte, Maladie de Crohn (), Maladie de Crohn (traitement médicamenteux), Maladies rares (diagnostic), Maladies rares (étiologie), Mâle, Méthotrexate (usage thérapeutique), Rectocolite hémorragique (), Rectocolite hémorragique (traitement médicamenteux), Reprise du traitement, Études rétrospectives.
- MESH :
- antagonistes et inhibiteurs : Facteur de nécrose tumorale alpha.
- diagnostic : Angiopathies intracrâniennes, Maladies rares.
- traitement médicamenteux : Maladie de Crohn, Rectocolite hémorragique.
- usage thérapeutique : Adalimumab, Anti-inflammatoires non stéroïdiens, Azathioprine, Certolizumab pégol, Immunosuppresseurs, Infliximab, Méthotrexate.
- étiologie : Angiopathies intracrâniennes, Maladies rares.
- Adulte, Adulte d'âge moyen, Association de médicaments, Femelle, Humains, Jeune adulte, Maladie de Crohn, Mâle, Rectocolite hémorragique, Reprise du traitement, Études rétrospectives.
English descriptors
- KwdEn :
- Adalimumab (therapeutic use), Adult, Anti-Inflammatory Agents, Non-Steroidal (therapeutic use), Azathioprine (therapeutic use), Cerebrovascular Disorders (diagnosis), Cerebrovascular Disorders (etiology), Certolizumab Pegol (therapeutic use), Colitis, Ulcerative (complications), Colitis, Ulcerative (drug therapy), Crohn Disease (complications), Crohn Disease (drug therapy), Drug Therapy, Combination, Female, Humans, Immunosuppressive Agents (therapeutic use), Infliximab (therapeutic use), Male, Methotrexate (therapeutic use), Middle Aged, Rare Diseases (diagnosis), Rare Diseases (etiology), Retreatment, Retrospective Studies, Tumor Necrosis Factor-alpha (antagonists & inhibitors), Young Adult.
- MESH :
- chemical , antagonists & inhibitors : Tumor Necrosis Factor-alpha.
- chemical , therapeutic use : Adalimumab, Anti-Inflammatory Agents, Non-Steroidal, Azathioprine, Certolizumab Pegol, Immunosuppressive Agents, Infliximab, Methotrexate.
- complications : Colitis, Ulcerative, Crohn Disease.
- diagnosis : Cerebrovascular Disorders, Rare Diseases.
- drug therapy : Colitis, Ulcerative, Crohn Disease.
- etiology : Cerebrovascular Disorders, Rare Diseases.
- Adult, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Retreatment, Retrospective Studies, Young Adult.
Abstract
Cerebrovascular accidents [CVA] have rarely been reported in inflammatory bowel disease [IBD] patients treated with anti-tumour necrosis alpha [anti-TNF alpha] agents. Our aim here was to describe the clinical course of CVA in these patients.
DOI: 10.1093/ecco-jcc/jjv042
PubMed: 25740813
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pubmed:25740813Le document en format XML
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<author><name sortKey="Li, Andy C Y" sort="Li, Andy C Y" uniqKey="Li A" first="Andy C Y" last="Li">Andy C Y. Li</name>
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<author><name sortKey="Bouguen, Guillaume" sort="Bouguen, Guillaume" uniqKey="Bouguen G" first="Guillaume" last="Bouguen">Guillaume Bouguen</name>
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<author><name sortKey="Yanai, Henit" sort="Yanai, Henit" uniqKey="Yanai H" first="Henit" last="Yanai">Henit Yanai</name>
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<author><name sortKey="Katsanos, Konstantinos H" sort="Katsanos, Konstantinos H" uniqKey="Katsanos K" first="Konstantinos H" last="Katsanos">Konstantinos H. Katsanos</name>
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<author><name sortKey="Subramaniam, Kavitha" sort="Subramaniam, Kavitha" uniqKey="Subramaniam K" first="Kavitha" last="Subramaniam">Kavitha Subramaniam</name>
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<country xml:lang="fr">Serbie</country>
<wicri:regionArea>Department of Gastroenterology, MMA Belgrade</wicri:regionArea>
</affiliation>
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<author><name sortKey="Zaganas, Ioannis V" sort="Zaganas, Ioannis V" uniqKey="Zaganas I" first="Ioannis V" last="Zaganas">Ioannis V. Zaganas</name>
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<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Neurology, University Hospital of Heraklion, Heraklion, Crete</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ben Horin, Shomron" sort="Ben Horin, Shomron" uniqKey="Ben Horin S" first="Shomron" last="Ben-Horin">Shomron Ben-Horin</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Gastroenterology, Sheba Medical Center, Tel-Aviv University, Tel-Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Gastroenterology, Sheba Medical Center, Tel-Aviv University, Tel-Aviv</wicri:regionArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Cerebrovascular events in inflammatory bowel disease patients treated with anti-tumour necrosis factor alpha agents.</title>
<author><name sortKey="Karmiris, Konstantinos" sort="Karmiris, Konstantinos" uniqKey="Karmiris K" first="Konstantinos" last="Karmiris">Konstantinos Karmiris</name>
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<author><name sortKey="Bossuyt, Peter" sort="Bossuyt, Peter" uniqKey="Bossuyt P" first="Peter" last="Bossuyt">Peter Bossuyt</name>
<affiliation wicri:level="1"><nlm:affiliation>Imelda GI Clinical Research Center, Bonheiden, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Imelda GI Clinical Research Center, Bonheiden</wicri:regionArea>
</affiliation>
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<author><name sortKey="Sorrentino, Dario" sort="Sorrentino, Dario" uniqKey="Sorrentino D" first="Dario" last="Sorrentino">Dario Sorrentino</name>
<affiliation wicri:level="1"><nlm:affiliation>IBD Center, Virginia Tech-Carilion School of Medicine, Roanoke, VA, USA and Department of Clinical and Experimental Medical Sciences, University of Udine School of Medicine, Udine, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>IBD Center, Virginia Tech-Carilion School of Medicine, Roanoke, VA, USA and Department of Clinical and Experimental Medical Sciences, University of Udine School of Medicine, Udine</wicri:regionArea>
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<author><name sortKey="Moreels, Tom" sort="Moreels, Tom" uniqKey="Moreels T" first="Tom" last="Moreels">Tom Moreels</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Hepato-gastroenterology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Hepato-gastroenterology, Cliniques Universitaires Saint-Luc, Brussels</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scarcelli, Antonella" sort="Scarcelli, Antonella" uniqKey="Scarcelli A" first="Antonella" last="Scarcelli">Antonella Scarcelli</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Gastroenterology, Azienda University Hospital, Policlinico di Modena, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Gastroenterology, Azienda University Hospital, Policlinico di Modena</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Legido, Jesus" sort="Legido, Jesus" uniqKey="Legido J" first="Jesus" last="Legido">Jesus Legido</name>
<affiliation wicri:level="1"><nlm:affiliation>Gastroenterology Unit, Segovia General Hospital, Segovia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Gastroenterology Unit, Segovia General Hospital, Segovia</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dotan, Iris" sort="Dotan, Iris" uniqKey="Dotan I" first="Iris" last="Dotan">Iris Dotan</name>
<affiliation wicri:level="1"><nlm:affiliation>IBD Center, Department of Gastroenterology and Liver Diseases and the Sackler School of Medicine, Sourasky Medical Center, Tel Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>IBD Center, Department of Gastroenterology and Liver Diseases and the Sackler School of Medicine, Sourasky Medical Center, Tel Aviv</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Naismith, Graham D" sort="Naismith, Graham D" uniqKey="Naismith G" first="Graham D" last="Naismith">Graham D. Naismith</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Gastroenterology, Paisley RAH, Glasgow, Scotland.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Écosse</region>
</placeName>
<wicri:cityArea>Department of Gastroenterology, Paisley RAH, Glasgow</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Jussila, Airi" sort="Jussila, Airi" uniqKey="Jussila A" first="Airi" last="Jussila">Airi Jussila</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Preiss, Jan C" sort="Preiss, Jan C" uniqKey="Preiss J" first="Jan C" last="Preiss">Jan C. Preiss</name>
<affiliation wicri:level="1"><nlm:affiliation>Charité-Universitätsmedizin, Berlin, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Charité-Universitätsmedizin, Berlin</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kruis, Wolfgang" sort="Kruis, Wolfgang" uniqKey="Kruis W" first="Wolfgang" last="Kruis">Wolfgang Kruis</name>
<affiliation wicri:level="1"><nlm:affiliation>Charité-Universitätsmedizin, Berlin, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Charité-Universitätsmedizin, Berlin</wicri:regionArea>
</affiliation>
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<author><name sortKey="Li, Andy C Y" sort="Li, Andy C Y" uniqKey="Li A" first="Andy C Y" last="Li">Andy C Y. Li</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Gastroenterology, Western Sussex Hospitals NHSFT, Worthing, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Gastroenterology, Western Sussex Hospitals NHSFT, Worthing</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bouguen, Guillaume" sort="Bouguen, Guillaume" uniqKey="Bouguen G" first="Guillaume" last="Bouguen">Guillaume Bouguen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Gastroenterology, University Hospital Pontchaillou, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Gastroenterology, University Hospital Pontchaillou, Rennes</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yanai, Henit" sort="Yanai, Henit" uniqKey="Yanai H" first="Henit" last="Yanai">Henit Yanai</name>
<affiliation wicri:level="1"><nlm:affiliation>Gastroenterology Unit, Segovia General Hospital, Segovia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Gastroenterology Unit, Segovia General Hospital, Segovia</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Steinwurz, Flavio" sort="Steinwurz, Flavio" uniqKey="Steinwurz F" first="Flavio" last="Steinwurz">Flavio Steinwurz</name>
<affiliation wicri:level="1"><nlm:affiliation>IBD Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>IBD Unit, Hospital Israelita Albert Einstein, Sao Paulo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Katsanos, Konstantinos H" sort="Katsanos, Konstantinos H" uniqKey="Katsanos K" first="Konstantinos H" last="Katsanos">Konstantinos H. Katsanos</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Gastroenterology, University Hospital of Ioannina, Greece.</nlm:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Division of Gastroenterology, University Hospital of Ioannina</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Subramaniam, Kavitha" sort="Subramaniam, Kavitha" uniqKey="Subramaniam K" first="Kavitha" last="Subramaniam">Kavitha Subramaniam</name>
<affiliation wicri:level="1"><nlm:affiliation>Gastroenterology and Hepatology Unit, Canberra Hospital, Canberra, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Gastroenterology and Hepatology Unit, Canberra Hospital, Canberra</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tarabar, Dino" sort="Tarabar, Dino" uniqKey="Tarabar D" first="Dino" last="Tarabar">Dino Tarabar</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Gastroenterology, MMA Belgrade, Serbia.</nlm:affiliation>
<country xml:lang="fr">Serbie</country>
<wicri:regionArea>Department of Gastroenterology, MMA Belgrade</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zaganas, Ioannis V" sort="Zaganas, Ioannis V" uniqKey="Zaganas I" first="Ioannis V" last="Zaganas">Ioannis V. Zaganas</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital of Heraklion, Heraklion, Crete, Greece.</nlm:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Neurology, University Hospital of Heraklion, Heraklion, Crete</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ben Horin, Shomron" sort="Ben Horin, Shomron" uniqKey="Ben Horin S" first="Shomron" last="Ben-Horin">Shomron Ben-Horin</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Gastroenterology, Sheba Medical Center, Tel-Aviv University, Tel-Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Gastroenterology, Sheba Medical Center, Tel-Aviv University, Tel-Aviv</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Crohn's & colitis</title>
<idno type="eISSN">1876-4479</idno>
<imprint><date when="2015" type="published">2015</date>
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<front><div type="abstract" xml:lang="en">Cerebrovascular accidents [CVA] have rarely been reported in inflammatory bowel disease [IBD] patients treated with anti-tumour necrosis alpha [anti-TNF alpha] agents. Our aim here was to describe the clinical course of CVA in these patients.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25740813</PMID>
<DateCreated><Year>2015</Year>
<Month>04</Month>
<Day>29</Day>
</DateCreated>
<DateCompleted><Year>2016</Year>
<Month>03</Month>
<Day>08</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>10</Month>
<Day>20</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1876-4479</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>9</Volume>
<Issue>5</Issue>
<PubDate><Year>2015</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Journal of Crohn's & colitis</Title>
<ISOAbbreviation>J Crohns Colitis</ISOAbbreviation>
</Journal>
<ArticleTitle>Cerebrovascular events in inflammatory bowel disease patients treated with anti-tumour necrosis factor alpha agents.</ArticleTitle>
<Pagination><MedlinePgn>382-9</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1093/ecco-jcc/jjv042</ELocationID>
<Abstract><AbstractText Label="BACKGROUND AND AIMS" NlmCategory="OBJECTIVE">Cerebrovascular accidents [CVA] have rarely been reported in inflammatory bowel disease [IBD] patients treated with anti-tumour necrosis alpha [anti-TNF alpha] agents. Our aim here was to describe the clinical course of CVA in these patients.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">This was a European Crohn's and Colitis Organisation [ECCO] retrospective observational study, performed as part of the CONFER [COllaborative Network For Exceptionally Rare case reports] project. A call to all ECCO members was made to report on IBD patients afflicted with CVA during treatment with anti-TNF alpha agents. Clinical data were recorded in a standardised case report form and analysed for event association with anti-TNF alpha treatment.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 19 patients were identified from 16 centres: 14 had Crohn's disease, four ulcerative colitis and one IBD colitis unclassified [median age at diagnosis: 38.0 years, range: 18.6-62.5]. Patients received anti-TNF alpha for a median duration of 11.8 months [range: 0-62] at CVA onset; seven had previously been treated with at least one other anti-TNF alpha agent. Complete neurological recovery was observed in 16 patients. Anti-TNF alpha was discontinued in 16/19 patients. However, recurrent CVA or neurological deterioration was not observed in any of the 11 patients who received anti-TNF alpha after CVA [eight resumed after temporary cessation, three continued without interruption] for a median follow-up of 39.8 months [range: 5.6-98.2].</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">These preliminary findings do not unequivocally indicate a causal role of anti-TNF alpha in CVA complicating IBD. Resuming or continuing anti-TNF alpha in IBD patients with CVA may be feasible and safe in selected cases, but careful weighing of IBD activity versus neurological status is prudent.</AbstractText>
<CopyrightInformation>Copyright © 2015 European Crohn’s and Colitis Organisation (ECCO). Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Karmiris</LastName>
<ForeName>Konstantinos</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, Venizeleio General Hospital, Heraklion, Crete, Greece kkarmiris@gmail.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bossuyt</LastName>
<ForeName>Peter</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Imelda GI Clinical Research Center, Bonheiden, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sorrentino</LastName>
<ForeName>Dario</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>IBD Center, Virginia Tech-Carilion School of Medicine, Roanoke, VA, USA and Department of Clinical and Experimental Medical Sciences, University of Udine School of Medicine, Udine, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Moreels</LastName>
<ForeName>Tom</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Hepato-gastroenterology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Scarcelli</LastName>
<ForeName>Antonella</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, Azienda University Hospital, Policlinico di Modena, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Legido</LastName>
<ForeName>Jesus</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Gastroenterology Unit, Segovia General Hospital, Segovia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dotan</LastName>
<ForeName>Iris</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>IBD Center, Department of Gastroenterology and Liver Diseases and the Sackler School of Medicine, Sourasky Medical Center, Tel Aviv, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Naismith</LastName>
<ForeName>Graham D</ForeName>
<Initials>GD</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, Paisley RAH, Glasgow, Scotland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jussila</LastName>
<ForeName>Airi</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Preiss</LastName>
<ForeName>Jan C</ForeName>
<Initials>JC</Initials>
<AffiliationInfo><Affiliation>Charité-Universitätsmedizin, Berlin, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kruis</LastName>
<ForeName>Wolfgang</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Charité-Universitätsmedizin, Berlin, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Andy C Y</ForeName>
<Initials>AC</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, Western Sussex Hospitals NHSFT, Worthing, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bouguen</LastName>
<ForeName>Guillaume</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, University Hospital Pontchaillou, Rennes, France.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Yanai</LastName>
<ForeName>Henit</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Gastroenterology Unit, Segovia General Hospital, Segovia, Spain.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Steinwurz</LastName>
<ForeName>Flavio</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>IBD Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Katsanos</LastName>
<ForeName>Konstantinos H</ForeName>
<Initials>KH</Initials>
<AffiliationInfo><Affiliation>Division of Gastroenterology, University Hospital of Ioannina, Greece.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Subramaniam</LastName>
<ForeName>Kavitha</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Gastroenterology and Hepatology Unit, Canberra Hospital, Canberra, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tarabar</LastName>
<ForeName>Dino</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, MMA Belgrade, Serbia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zaganas</LastName>
<ForeName>Ioannis V</ForeName>
<Initials>IV</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University Hospital of Heraklion, Heraklion, Crete, Greece.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ben-Horin</LastName>
<ForeName>Shomron</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, Sheba Medical Center, Tel-Aviv University, Tel-Aviv, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>ECCO CONFER investigators</CollectiveName>
</Author>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D064888">Observational Study</PublicationType>
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<Month>03</Month>
<Day>04</Day>
</ArticleDate>
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<MedlineTA>J Crohns Colitis</MedlineTA>
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