AustralieFrV1, PubMed, Curation, bibRecord, 002A74

Association of Cardiometabolic Multimorbidity With Mortality.

Identifieur interne : 002A74 ( PubMed/Curation ); précédent : 002A73; suivant : 002A75

Association of Cardiometabolic Multimorbidity With Mortality.

Auteurs : Emanuele Di Angelantonio [Royaume-Uni] ; Stephen Kaptoge [Royaume-Uni] ; David Wormser [Royaume-Uni] ; Peter Willeit [Royaume-Uni] ; Adam S. Butterworth [Royaume-Uni] ; Narinder Bansal [Royaume-Uni] ; Linda M. O'Keeffe [Royaume-Uni] ; Pei Gao [Royaume-Uni] ; Angela M. Wood [Royaume-Uni] ; Stephen Burgess [Royaume-Uni] ; Daniel F. Freitag [Royaume-Uni] ; Lisa Pennells [Royaume-Uni] ; Sanne A. Peters [Pays-Bas] ; Carole L. Hart [Royaume-Uni] ; Lise Lund H Heim [Norvège] ; Richard F. Gillum [États-Unis] ; B Rge G. Nordestgaard [Danemark] ; Bruce M. Psaty [États-Unis] ; Bu B. Yeap ; Matthew W. Knuiman ; Paul J. Nietert ; Jussi Kauhanen ; Jukka T. Salonen [Finlande] ; Lewis H. Kuller [États-Unis] ; Leon A. Simons [Australie] ; Yvonne T. Van Der Schouw [Pays-Bas] ; Elizabeth Barrett-Connor ; Randi Selmer [Norvège] ; Carlos J. Crespo [États-Unis] ; Beatriz Rodriguez ; W M Monique Verschuren [Pays-Bas] ; Veikko Salomaa [Finlande] ; Kurt Sv Rdsudd [Suède] ; Pim Van Der Harst [Pays-Bas] ; Cecilia Björkelund [Suède] ; Lars Wilhelmsen [Suède] ; Robert B. Wallace [États-Unis] ; Hermann Brenner [Allemagne] ; Philippe Amouyel [France] ; Elizabeth L M. Barr [Australie] ; Hiroyasu Iso [Japon] ; Altan Onat [Turquie] ; Maurizio Trevisan [États-Unis] ; Ralph B. D'Agostino [États-Unis] ; Cyrus Cooper [Royaume-Uni] ; Maryam Kavousi [Pays-Bas] ; Lennart Welin [Suède] ; Ronan Roussel [France] ; Frank B. Hu [États-Unis] ; Shinichi Sato [Japon] ; Karina W. Davidson [États-Unis] ; Barbara V. Howard [États-Unis] ; Maarten J G. Leening [Pays-Bas] ; Maarten Leening [Pays-Bas] ; Annika Rosengren [Suède] ; Marcus Dörr [Allemagne] ; Dorly J H. Deeg [Pays-Bas] ; Stefan Kiechl [Autriche] ; Coen D A. Stehouwer [Pays-Bas] ; Aulikki Nissinen [Finlande] ; Simona Giampaoli [Italie] ; Chiara Donfrancesco [Italie] ; Daan Kromhout [Pays-Bas] ; Jackie F. Price [Royaume-Uni] ; Annette Peters [Allemagne] ; Tom W. Meade [Royaume-Uni] ; Edoardo Casiglia [Italie] ; Debbie A. Lawlor [Royaume-Uni] ; John Gallacher [Royaume-Uni] ; Dorothea Nagel [Allemagne] ; Oscar H. Franco [Pays-Bas] ; Gerd Assmann [Allemagne] ; Gilles R. Dagenais [Canada] ; J Wouter Jukema [Pays-Bas] ; Johan Sundström [Suède] ; Mark Woodward [Australie] ; Eric J. Brunner [Royaume-Uni] ; Kay-Tee Khaw [Royaume-Uni] ; Nicholas J. Wareham [Royaume-Uni] ; Eric A. Whitsel ; Inger Nj Lstad [Norvège] ; Bo Hedblad [Suède] ; Sylvia Wassertheil-Smoller [États-Unis] ; Gunnar Engström [Suède] ; Wayne D. Rosamond ; Elizabeth Selvin [États-Unis] ; Naveed Sattar [Royaume-Uni] ; Simon G. Thompson [Royaume-Uni] ; John Danesh [Royaume-Uni]

Source :

JAMA [ 1538-3598 ] ; 2015.

RBID : pubmed:26151266

Descripteurs français

KwdFr :
- Accident vasculaire cérébral (épidémiologie), Adulte, Adulte d'âge moyen, Comorbidité, Diabète (épidémiologie), Espérance de vie, Facteurs de risque, Femelle, Humains, Infarctus du myocarde (épidémiologie), Mortalité, Mâle, Sujet âgé.
MESH :
- épidémiologie : Accident vasculaire cérébral, Diabète, Infarctus du myocarde.
- Adulte, Adulte d'âge moyen, Comorbidité, Espérance de vie, Facteurs de risque, Femelle, Humains, Mortalité, Mâle, Sujet âgé.

English descriptors

KwdEn :
- Adult, Aged, Comorbidity, Diabetes Mellitus (epidemiology), Female, Humans, Life Expectancy, Male, Middle Aged, Mortality, Myocardial Infarction (epidemiology), Risk Factors, Stroke (epidemiology).
MESH :
- epidemiology : Diabetes Mellitus, Myocardial Infarction, Stroke.
- Adult, Aged, Comorbidity, Female, Humans, Life Expectancy, Male, Middle Aged, Mortality, Risk Factors.

Abstract

The prevalence of cardiometabolic multimorbidity is increasing.

DOI: 10.1001/jama.2015.7008
PubMed: 26151266

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Bu B. Yeap

<affiliation><nlm:affiliation>University of Western Australia, Perth.</nlm:affiliation>
<wicri:noCountry code="subField">Perth</wicri:noCountry>
</affiliation>

Matthew W. Knuiman

<affiliation><nlm:affiliation>University of Western Australia, Perth.</nlm:affiliation>
<wicri:noCountry code="subField">Perth</wicri:noCountry>
</affiliation>

Paul J. Nietert

<affiliation><nlm:affiliation>Department of Public Health Sciences, Medical University of South Carolina, Charleston.</nlm:affiliation>
<wicri:noCountry code="subField">Charleston</wicri:noCountry>
</affiliation>

Jussi Kauhanen

<affiliation><nlm:affiliation>University of Eastern Finland, Kuopio.</nlm:affiliation>
<wicri:noCountry code="subField">Kuopio</wicri:noCountry>
</affiliation>

Elizabeth Barrett-Connor

<affiliation><nlm:affiliation>University of California-San Diego, La Jolla.</nlm:affiliation>
<wicri:noCountry code="subField">La Jolla</wicri:noCountry>
</affiliation>

Beatriz Rodriguez

<affiliation><nlm:affiliation>University of Hawaii, Honolulu.</nlm:affiliation>
<wicri:noCountry code="subField">Honolulu</wicri:noCountry>
</affiliation>

Eric A. Whitsel

<affiliation><nlm:affiliation>Department of Medicine, University of North Carolina, Chapel Hill65Department of Epidemiology, University of North Carolina, Chapel Hill.</nlm:affiliation>
<wicri:noCountry code="subField">Chapel Hill</wicri:noCountry>
</affiliation>

Wayne D. Rosamond

<affiliation><nlm:affiliation>University of North Carolina, Chapel Hill.</nlm:affiliation>
<wicri:noCountry code="subField">Chapel Hill</wicri:noCountry>
</affiliation>

Le document en format XML

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<author><name sortKey="Knuiman, Matthew W" sort="Knuiman, Matthew W" uniqKey="Knuiman M" first="Matthew W" last="Knuiman">Matthew W. Knuiman</name>
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<wicri:cityArea>Portland State University, Portland</wicri:cityArea>
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<author><name sortKey="Rodriguez, Beatriz" sort="Rodriguez, Beatriz" uniqKey="Rodriguez B" first="Beatriz" last="Rodriguez">Beatriz Rodriguez</name>
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<author><name sortKey="Verschuren, W M Monique" sort="Verschuren, W M Monique" uniqKey="Verschuren W" first="W M Monique" last="Verschuren">W M Monique Verschuren</name>
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<author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name>
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<country xml:lang="fr">Suède</country>
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</affiliation>
</author>
<author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name>
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<author><name sortKey="Bjorkelund, Cecilia" sort="Bjorkelund, Cecilia" uniqKey="Bjorkelund C" first="Cecilia" last="Björkelund">Cecilia Björkelund</name>
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<country xml:lang="fr">Suède</country>
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<author><name sortKey="Wilhelmsen, Lars" sort="Wilhelmsen, Lars" uniqKey="Wilhelmsen L" first="Lars" last="Wilhelmsen">Lars Wilhelmsen</name>
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<country xml:lang="fr">Suède</country>
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</affiliation>
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<author><name sortKey="Wallace, Robert B" sort="Wallace, Robert B" uniqKey="Wallace R" first="Robert B" last="Wallace">Robert B. Wallace</name>
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<author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name>
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<author><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name>
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<author><name sortKey="Barr, Elizabeth L M" sort="Barr, Elizabeth L M" uniqKey="Barr E" first="Elizabeth L M" last="Barr">Elizabeth L M. Barr</name>
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<author><name sortKey="Iso, Hiroyasu" sort="Iso, Hiroyasu" uniqKey="Iso H" first="Hiroyasu" last="Iso">Hiroyasu Iso</name>
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<country xml:lang="fr">Japon</country>
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<author><name sortKey="D Agostino, Ralph B" sort="D Agostino, Ralph B" uniqKey="D Agostino R" first="Ralph B" last="D'Agostino">Ralph B. D'Agostino</name>
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<author><name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name>
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<author><name sortKey="Kavousi, Maryam" sort="Kavousi, Maryam" uniqKey="Kavousi M" first="Maryam" last="Kavousi">Maryam Kavousi</name>
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<author><name sortKey="Hu, Frank B" sort="Hu, Frank B" uniqKey="Hu F" first="Frank B" last="Hu">Frank B. Hu</name>
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<author><name sortKey="Sato, Shinichi" sort="Sato, Shinichi" uniqKey="Sato S" first="Shinichi" last="Sato">Shinichi Sato</name>
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<author><name sortKey="Davidson, Karina W" sort="Davidson, Karina W" uniqKey="Davidson K" first="Karina W" last="Davidson">Karina W. Davidson</name>
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<author><name sortKey="Leening, Maarten J G" sort="Leening, Maarten J G" uniqKey="Leening M" first="Maarten J G" last="Leening">Maarten J G. Leening</name>
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<author><name sortKey="Rosengren, Annika" sort="Rosengren, Annika" uniqKey="Rosengren A" first="Annika" last="Rosengren">Annika Rosengren</name>
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<author><name sortKey="Deeg, Dorly J H" sort="Deeg, Dorly J H" uniqKey="Deeg D" first="Dorly J H" last="Deeg">Dorly J H. Deeg</name>
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<author><name sortKey="Stehouwer, Coen D A" sort="Stehouwer, Coen D A" uniqKey="Stehouwer C" first="Coen D A" last="Stehouwer">Coen D A. Stehouwer</name>
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<author><name sortKey="Nissinen, Aulikki" sort="Nissinen, Aulikki" uniqKey="Nissinen A" first="Aulikki" last="Nissinen">Aulikki Nissinen</name>
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<author><name sortKey="Kromhout, Daan" sort="Kromhout, Daan" uniqKey="Kromhout D" first="Daan" last="Kromhout">Daan Kromhout</name>
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<author><name sortKey="Price, Jackie F" sort="Price, Jackie F" uniqKey="Price J" first="Jackie F" last="Price">Jackie F. Price</name>
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<author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name>
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<author><name sortKey="Meade, Tom W" sort="Meade, Tom W" uniqKey="Meade T" first="Tom W" last="Meade">Tom W. Meade</name>
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<author><name sortKey="Gallacher, John" sort="Gallacher, John" uniqKey="Gallacher J" first="John" last="Gallacher">John Gallacher</name>
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<author><name sortKey="Woodward, Mark" sort="Woodward, Mark" uniqKey="Woodward M" first="Mark" last="Woodward">Mark Woodward</name>
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<author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
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<author><name sortKey="Rosamond, Wayne D" sort="Rosamond, Wayne D" uniqKey="Rosamond W" first="Wayne D" last="Rosamond">Wayne D. Rosamond</name>
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<author><name sortKey="Danesh, John" sort="Danesh, John" uniqKey="Danesh J" first="John" last="Danesh">John Danesh</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Association of Cardiometabolic Multimorbidity With Mortality.</title>
<author><name sortKey="Di Angelantonio, Emanuele" sort="Di Angelantonio, Emanuele" uniqKey="Di Angelantonio E" first="Emanuele" last="Di Angelantonio">Emanuele Di Angelantonio</name>
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<author><name sortKey="Willeit, Peter" sort="Willeit, Peter" uniqKey="Willeit P" first="Peter" last="Willeit">Peter Willeit</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Butterworth, Adam S" sort="Butterworth, Adam S" uniqKey="Butterworth A" first="Adam S" last="Butterworth">Adam S. Butterworth</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bansal, Narinder" sort="Bansal, Narinder" uniqKey="Bansal N" first="Narinder" last="Bansal">Narinder Bansal</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="O Keeffe, Linda M" sort="O Keeffe, Linda M" uniqKey="O Keeffe L" first="Linda M" last="O'Keeffe">Linda M. O'Keeffe</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Gao, Pei" sort="Gao, Pei" uniqKey="Gao P" first="Pei" last="Gao">Pei Gao</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wood, Angela M" sort="Wood, Angela M" uniqKey="Wood A" first="Angela M" last="Wood">Angela M. Wood</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Burgess, Stephen" sort="Burgess, Stephen" uniqKey="Burgess S" first="Stephen" last="Burgess">Stephen Burgess</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Freitag, Daniel F" sort="Freitag, Daniel F" uniqKey="Freitag D" first="Daniel F" last="Freitag">Daniel F. Freitag</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Pennells, Lisa" sort="Pennells, Lisa" uniqKey="Pennells L" first="Lisa" last="Pennells">Lisa Pennells</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Peters, Sanne A" sort="Peters, Sanne A" uniqKey="Peters S" first="Sanne A" last="Peters">Sanne A. Peters</name>
<affiliation wicri:level="1"><nlm:affiliation>University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>University Medical Center Utrecht, Utrecht</wicri:regionArea>
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<author><name sortKey="Hart, Carole L" sort="Hart, Carole L" uniqKey="Hart C" first="Carole L" last="Hart">Carole L. Hart</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Glasgow, Glasgow, Scotland.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Écosse</region>
</placeName>
<wicri:cityArea>University of Glasgow, Glasgow</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="H Heim, Lise Lund" sort="H Heim, Lise Lund" uniqKey="H Heim L" first="Lise Lund" last="H Heim">Lise Lund H Heim</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Oslo, Oslo, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>University of Oslo, Oslo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gillum, Richard F" sort="Gillum, Richard F" uniqKey="Gillum R" first="Richard F" last="Gillum">Richard F. Gillum</name>
<affiliation wicri:level="2"><nlm:affiliation>Howard University College of Medicine, Washington, DC.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">District de Columbia</region>
</placeName>
<wicri:cityArea>Howard University College of Medicine, Washington</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G" last="Nordestgaard">B Rge G. Nordestgaard</name>
<affiliation wicri:level="1"><nlm:affiliation>Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Copenhagen University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name>
<affiliation wicri:level="4"><nlm:affiliation>University of Washington, Seattle.</nlm:affiliation>
<orgName type="university">Université de Washington</orgName>
<country>États-Unis</country>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yeap, Bu B" sort="Yeap, Bu B" uniqKey="Yeap B" first="Bu B" last="Yeap">Bu B. Yeap</name>
<affiliation><nlm:affiliation>University of Western Australia, Perth.</nlm:affiliation>
<wicri:noCountry code="subField">Perth</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Knuiman, Matthew W" sort="Knuiman, Matthew W" uniqKey="Knuiman M" first="Matthew W" last="Knuiman">Matthew W. Knuiman</name>
<affiliation><nlm:affiliation>University of Western Australia, Perth.</nlm:affiliation>
<wicri:noCountry code="subField">Perth</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Nietert, Paul J" sort="Nietert, Paul J" uniqKey="Nietert P" first="Paul J" last="Nietert">Paul J. Nietert</name>
<affiliation><nlm:affiliation>Department of Public Health Sciences, Medical University of South Carolina, Charleston.</nlm:affiliation>
<wicri:noCountry code="subField">Charleston</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kauhanen, Jussi" sort="Kauhanen, Jussi" uniqKey="Kauhanen J" first="Jussi" last="Kauhanen">Jussi Kauhanen</name>
<affiliation><nlm:affiliation>University of Eastern Finland, Kuopio.</nlm:affiliation>
<wicri:noCountry code="subField">Kuopio</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Salonen, Jukka T" sort="Salonen, Jukka T" uniqKey="Salonen J" first="Jukka T" last="Salonen">Jukka T. Salonen</name>
<affiliation wicri:level="1"><nlm:affiliation>Metabolic Analytical Services Inc, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Metabolic Analytical Services Inc, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kuller, Lewis H" sort="Kuller, Lewis H" uniqKey="Kuller L" first="Lewis H" last="Kuller">Lewis H. Kuller</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Pittsburgh, Pittsburgh, Pennsylvania.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>University of Pittsburgh, Pittsburgh</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Simons, Leon A" sort="Simons, Leon A" uniqKey="Simons L" first="Leon A" last="Simons">Leon A. Simons</name>
<affiliation wicri:level="1"><nlm:affiliation>University of New South Wales, New South Wales, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of New South Wales, New South Wales</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Der Schouw, Yvonne T" sort="Van Der Schouw, Yvonne T" uniqKey="Van Der Schouw Y" first="Yvonne T" last="Van Der Schouw">Yvonne T. Van Der Schouw</name>
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<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>University Medical Center Utrecht, Utrecht</wicri:regionArea>
</affiliation>
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<author><name sortKey="Barrett Connor, Elizabeth" sort="Barrett Connor, Elizabeth" uniqKey="Barrett Connor E" first="Elizabeth" last="Barrett-Connor">Elizabeth Barrett-Connor</name>
<affiliation><nlm:affiliation>University of California-San Diego, La Jolla.</nlm:affiliation>
<wicri:noCountry code="subField">La Jolla</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Selmer, Randi" sort="Selmer, Randi" uniqKey="Selmer R" first="Randi" last="Selmer">Randi Selmer</name>
<affiliation wicri:level="1"><nlm:affiliation>Norwegian Institute of Public Health, Oslo, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Norwegian Institute of Public Health, Oslo</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Crespo, Carlos J" sort="Crespo, Carlos J" uniqKey="Crespo C" first="Carlos J" last="Crespo">Carlos J. Crespo</name>
<affiliation wicri:level="2"><nlm:affiliation>Portland State University, Portland, Oregon.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Oregon</region>
</placeName>
<wicri:cityArea>Portland State University, Portland</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Rodriguez, Beatriz" sort="Rodriguez, Beatriz" uniqKey="Rodriguez B" first="Beatriz" last="Rodriguez">Beatriz Rodriguez</name>
<affiliation><nlm:affiliation>University of Hawaii, Honolulu.</nlm:affiliation>
<wicri:noCountry code="subField">Honolulu</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Verschuren, W M Monique" sort="Verschuren, W M Monique" uniqKey="Verschuren W" first="W M Monique" last="Verschuren">W M Monique Verschuren</name>
<affiliation wicri:level="1"><nlm:affiliation>National Institute for Public Health and the Environment, Bilthoven, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>National Institute for Public Health and the Environment, Bilthoven</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name>
<affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sv Rdsudd, Kurt" sort="Sv Rdsudd, Kurt" uniqKey="Sv Rdsudd K" first="Kurt" last="Sv Rdsudd">Kurt Sv Rdsudd</name>
<affiliation wicri:level="1"><nlm:affiliation>Uppsala University, Uppsala, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Uppsala University, Uppsala</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name>
<affiliation wicri:level="1"><nlm:affiliation>University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bjorkelund, Cecilia" sort="Bjorkelund, Cecilia" uniqKey="Bjorkelund C" first="Cecilia" last="Björkelund">Cecilia Björkelund</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>University of Gothenburg, Gothenburg</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wilhelmsen, Lars" sort="Wilhelmsen, Lars" uniqKey="Wilhelmsen L" first="Lars" last="Wilhelmsen">Lars Wilhelmsen</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>University of Gothenburg, Gothenburg</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wallace, Robert B" sort="Wallace, Robert B" uniqKey="Wallace R" first="Robert B" last="Wallace">Robert B. Wallace</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology, University of Iowa, Iowa City.</nlm:affiliation>
<orgName type="university">Université de l'Iowa</orgName>
<country>États-Unis</country>
<placeName><settlement type="city">Iowa City</settlement>
<region type="state">Iowa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut Pasteur de Lille, Lille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barr, Elizabeth L M" sort="Barr, Elizabeth L M" uniqKey="Barr E" first="Elizabeth L M" last="Barr">Elizabeth L M. Barr</name>
<affiliation wicri:level="1"><nlm:affiliation>Baker IDI Heart and Diabetes Institute, Victoria, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Baker IDI Heart and Diabetes Institute, Victoria</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Iso, Hiroyasu" sort="Iso, Hiroyasu" uniqKey="Iso H" first="Hiroyasu" last="Iso">Hiroyasu Iso</name>
<affiliation wicri:level="1"><nlm:affiliation>Osaka University, Suita, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Osaka University, Suita</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Onat, Altan" sort="Onat, Altan" uniqKey="Onat A" first="Altan" last="Onat">Altan Onat</name>
<affiliation wicri:level="1"><nlm:affiliation>Istanbul University, Istanbul, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Istanbul University, Istanbul</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trevisan, Maurizio" sort="Trevisan, Maurizio" uniqKey="Trevisan M" first="Maurizio" last="Trevisan">Maurizio Trevisan</name>
<affiliation wicri:level="2"><nlm:affiliation>City College of New York, New York, New York.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>City College of New York, New York</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="D Agostino, Ralph B" sort="D Agostino, Ralph B" uniqKey="D Agostino R" first="Ralph B" last="D'Agostino">Ralph B. D'Agostino</name>
<affiliation wicri:level="2"><nlm:affiliation>Boston University, Boston, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Boston University, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Southampton, Southampton, England32University of Oxford, Oxford, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Southampton, Southampton, England32University of Oxford, Oxford</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Kavousi, Maryam" sort="Kavousi, Maryam" uniqKey="Kavousi M" first="Maryam" last="Kavousi">Maryam Kavousi</name>
<affiliation wicri:level="1"><nlm:affiliation>Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Erasmus Medical Center, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Welin, Lennart" sort="Welin, Lennart" uniqKey="Welin L" first="Lennart" last="Welin">Lennart Welin</name>
<affiliation wicri:level="1"><nlm:affiliation>Lidköping Hospital, Lidköping, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lidköping Hospital, Lidköping</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Roussel, Ronan" sort="Roussel, Ronan" uniqKey="Roussel R" first="Ronan" last="Roussel">Ronan Roussel</name>
<affiliation wicri:level="1"><nlm:affiliation>INSERM, Centre de Recherche des Cordeliers, Paris, France36Université Paris Diderot, Paris, France37Diabétologie, AP-HP, Département Hospitalo-Universitaire FIRE, Hôpital Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, Centre de Recherche des Cordeliers, Paris, France36Université Paris Diderot, Paris, France37Diabétologie, AP-HP, Département Hospitalo-Universitaire FIRE, Hôpital Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hu, Frank B" sort="Hu, Frank B" uniqKey="Hu F" first="Frank B" last="Hu">Frank B. Hu</name>
<affiliation wicri:level="2"><nlm:affiliation>Harvard School of Public Health, Boston, Massachusetts.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Harvard School of Public Health, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sato, Shinichi" sort="Sato, Shinichi" uniqKey="Sato S" first="Shinichi" last="Sato">Shinichi Sato</name>
<affiliation wicri:level="1"><nlm:affiliation>Osaka Medical Center for Health Science and Promotion/Chiba Prefectural Institute of Public Health, Suita, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Osaka Medical Center for Health Science and Promotion/Chiba Prefectural Institute of Public Health, Suita</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Davidson, Karina W" sort="Davidson, Karina W" uniqKey="Davidson K" first="Karina W" last="Davidson">Karina W. Davidson</name>
<affiliation wicri:level="2"><nlm:affiliation>Columbia University Medical Center, New York, New York.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Columbia University Medical Center, New York</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Howard, Barbara V" sort="Howard, Barbara V" uniqKey="Howard B" first="Barbara V" last="Howard">Barbara V. Howard</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>MedStar Health Research Institute, Hyattsville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Leening, Maarten J G" sort="Leening, Maarten J G" uniqKey="Leening M" first="Maarten J G" last="Leening">Maarten J G. Leening</name>
<affiliation wicri:level="1"><nlm:affiliation>Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Erasmus Medical Center, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Leening, Maarten" sort="Leening, Maarten" uniqKey="Leening M" first="Maarten" last="Leening">Maarten Leening</name>
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<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Erasmus Medical Center, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rosengren, Annika" sort="Rosengren, Annika" uniqKey="Rosengren A" first="Annika" last="Rosengren">Annika Rosengren</name>
<affiliation wicri:level="1"><nlm:affiliation>Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dorr, Marcus" sort="Dorr, Marcus" uniqKey="Dorr M" first="Marcus" last="Dörr">Marcus Dörr</name>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>University Medicine Greifswald, Greifswald, Germany44DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, Greifswald</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deeg, Dorly J H" sort="Deeg, Dorly J H" uniqKey="Deeg D" first="Dorly J H" last="Deeg">Dorly J H. Deeg</name>
<affiliation wicri:level="1"><nlm:affiliation>Vrije Universiteit Medical Center, Amsterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Vrije Universiteit Medical Center, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kiechl, Stefan" sort="Kiechl, Stefan" uniqKey="Kiechl S" first="Stefan" last="Kiechl">Stefan Kiechl</name>
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<author><name sortKey="Stehouwer, Coen D A" sort="Stehouwer, Coen D A" uniqKey="Stehouwer C" first="Coen D A" last="Stehouwer">Coen D A. Stehouwer</name>
<affiliation wicri:level="1"><nlm:affiliation>Maastricht University Medical Centre, Maastricht, the Netherlands.</nlm:affiliation>
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<wicri:regionArea>Maastricht University Medical Centre, Maastricht</wicri:regionArea>
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<author><name sortKey="Nissinen, Aulikki" sort="Nissinen, Aulikki" uniqKey="Nissinen A" first="Aulikki" last="Nissinen">Aulikki Nissinen</name>
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<author><name sortKey="Giampaoli, Simona" sort="Giampaoli, Simona" uniqKey="Giampaoli S" first="Simona" last="Giampaoli">Simona Giampaoli</name>
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<author><name sortKey="Price, Jackie F" sort="Price, Jackie F" uniqKey="Price J" first="Jackie F" last="Price">Jackie F. Price</name>
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</placeName>
<wicri:cityArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:cityArea>
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<author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany52German Research Center for Cardiovascular Research (DZHK eV), Partner-Site Munich, Munich</wicri:regionArea>
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</author>
<author><name sortKey="Meade, Tom W" sort="Meade, Tom W" uniqKey="Meade T" first="Tom W" last="Meade">Tom W. Meade</name>
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</placeName>
<wicri:cityArea>London School of Hygiene and Tropical Medicine, London</wicri:cityArea>
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<author><name sortKey="Casiglia, Edoardo" sort="Casiglia, Edoardo" uniqKey="Casiglia E" first="Edoardo" last="Casiglia">Edoardo Casiglia</name>
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<author><name sortKey="Lawlor, Debbie A" sort="Lawlor, Debbie A" uniqKey="Lawlor D" first="Debbie A" last="Lawlor">Debbie A. Lawlor</name>
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</placeName>
<wicri:cityArea>University of Bristol, Bristol</wicri:cityArea>
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<author><name sortKey="Gallacher, John" sort="Gallacher, John" uniqKey="Gallacher J" first="John" last="Gallacher">John Gallacher</name>
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</placeName>
<wicri:cityArea>Cardiff University, Cardiff</wicri:cityArea>
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<author><name sortKey="Nagel, Dorothea" sort="Nagel, Dorothea" uniqKey="Nagel D" first="Dorothea" last="Nagel">Dorothea Nagel</name>
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<author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H" last="Franco">Oscar H. Franco</name>
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<author><name sortKey="Assmann, Gerd" sort="Assmann, Gerd" uniqKey="Assmann G" first="Gerd" last="Assmann">Gerd Assmann</name>
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<author><name sortKey="Dagenais, Gilles R" sort="Dagenais, Gilles R" uniqKey="Dagenais G" first="Gilles R" last="Dagenais">Gilles R. Dagenais</name>
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<country xml:lang="fr">Suède</country>
<wicri:regionArea>Uppsala University, Uppsala</wicri:regionArea>
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<author><name sortKey="Woodward, Mark" sort="Woodward, Mark" uniqKey="Woodward M" first="Mark" last="Woodward">Mark Woodward</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Sydney, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Sydney, Sydney</wicri:regionArea>
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<author><name sortKey="Brunner, Eric J" sort="Brunner, Eric J" uniqKey="Brunner E" first="Eric J" last="Brunner">Eric J. Brunner</name>
<affiliation wicri:level="2"><nlm:affiliation>University College London, London, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University College London, London</wicri:cityArea>
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<author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name>
<affiliation wicri:level="2"><nlm:affiliation>Medical Research Council Epidemiology Unit, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>Medical Research Council Epidemiology Unit, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Whitsel, Eric A" sort="Whitsel, Eric A" uniqKey="Whitsel E" first="Eric A" last="Whitsel">Eric A. Whitsel</name>
<affiliation><nlm:affiliation>Department of Medicine, University of North Carolina, Chapel Hill65Department of Epidemiology, University of North Carolina, Chapel Hill.</nlm:affiliation>
<wicri:noCountry code="subField">Chapel Hill</wicri:noCountry>
</affiliation>
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<author><name sortKey="Nj Lstad, Inger" sort="Nj Lstad, Inger" uniqKey="Nj Lstad I" first="Inger" last="Nj Lstad">Inger Nj Lstad</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Tromsø, Tromsø, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>University of Tromsø, Tromsø</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hedblad, Bo" sort="Hedblad, Bo" uniqKey="Hedblad B" first="Bo" last="Hedblad">Bo Hedblad</name>
<affiliation wicri:level="1"><nlm:affiliation>Lund University, Lund, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University, Lund</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wassertheil Smoller, Sylvia" sort="Wassertheil Smoller, Sylvia" uniqKey="Wassertheil Smoller S" first="Sylvia" last="Wassertheil-Smoller">Sylvia Wassertheil-Smoller</name>
<affiliation wicri:level="2"><nlm:affiliation>Albert Einstein College of Medicine, New York, New York.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Albert Einstein College of Medicine, New York</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Engstrom, Gunnar" sort="Engstrom, Gunnar" uniqKey="Engstrom G" first="Gunnar" last="Engström">Gunnar Engström</name>
<affiliation wicri:level="1"><nlm:affiliation>Lund University, Lund, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University, Lund</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rosamond, Wayne D" sort="Rosamond, Wayne D" uniqKey="Rosamond W" first="Wayne D" last="Rosamond">Wayne D. Rosamond</name>
<affiliation><nlm:affiliation>University of North Carolina, Chapel Hill.</nlm:affiliation>
<wicri:noCountry code="subField">Chapel Hill</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Selvin, Elizabeth" sort="Selvin, Elizabeth" uniqKey="Selvin E" first="Elizabeth" last="Selvin">Elizabeth Selvin</name>
<affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins University, Baltimore, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Johns Hopkins University, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Glasgow, Glasgow, Scotland.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Écosse</region>
</placeName>
<wicri:cityArea>University of Glasgow, Glasgow</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Thompson, Simon G" sort="Thompson, Simon G" uniqKey="Thompson S" first="Simon G" last="Thompson">Simon G. Thompson</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Danesh, John" sort="Danesh, John" uniqKey="Danesh J" first="John" last="Danesh">John Danesh</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Cambridge, Cambridge, England.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Angleterre</region>
</placeName>
<wicri:cityArea>University of Cambridge, Cambridge</wicri:cityArea>
</affiliation>
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<series><title level="j">JAMA</title>
<idno type="eISSN">1538-3598</idno>
<imprint><date when="2015" type="published">2015</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Comorbidity</term>
<term>Diabetes Mellitus (epidemiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Life Expectancy</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mortality</term>
<term>Myocardial Infarction (epidemiology)</term>
<term>Risk Factors</term>
<term>Stroke (epidemiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Accident vasculaire cérébral (épidémiologie)</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Comorbidité</term>
<term>Diabète (épidémiologie)</term>
<term>Espérance de vie</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Infarctus du myocarde (épidémiologie)</term>
<term>Mortalité</term>
<term>Mâle</term>
<term>Sujet âgé</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Diabetes Mellitus</term>
<term>Myocardial Infarction</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Accident vasculaire cérébral</term>
<term>Diabète</term>
<term>Infarctus du myocarde</term>
</keywords>
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<term>Aged</term>
<term>Comorbidity</term>
<term>Female</term>
<term>Humans</term>
<term>Life Expectancy</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mortality</term>
<term>Risk Factors</term>
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<term>Adulte d'âge moyen</term>
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<term>Espérance de vie</term>
<term>Facteurs de risque</term>
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<term>Humains</term>
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<front><div type="abstract" xml:lang="en">The prevalence of cardiometabolic multimorbidity is increasing.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26151266</PMID>
<DateCreated><Year>2015</Year>
<Month>07</Month>
<Day>08</Day>
</DateCreated>
<DateCompleted><Year>2015</Year>
<Month>07</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>09</Month>
<Day>22</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1538-3598</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>314</Volume>
<Issue>1</Issue>
<PubDate><Year>2015</Year>
<Month>Jul</Month>
<Day>07</Day>
</PubDate>
</JournalIssue>
<Title>JAMA</Title>
<ISOAbbreviation>JAMA</ISOAbbreviation>
</Journal>
<ArticleTitle>Association of Cardiometabolic Multimorbidity With Mortality.</ArticleTitle>
<Pagination><MedlinePgn>52-60</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1001/jama.2015.7008</ELocationID>
<Abstract><AbstractText Label="IMPORTANCE" NlmCategory="OBJECTIVE">The prevalence of cardiometabolic multimorbidity is increasing.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To estimate reductions in life expectancy associated with cardiometabolic multimorbidity.</AbstractText>
<AbstractText Label="DESIGN, SETTING, AND PARTICIPANTS" NlmCategory="METHODS">Age- and sex-adjusted mortality rates and hazard ratios (HRs) were calculated using individual participant data from the Emerging Risk Factors Collaboration (689,300 participants; 91 cohorts; years of baseline surveys: 1960-2007; latest mortality follow-up: April 2013; 128,843 deaths). The HRs from the Emerging Risk Factors Collaboration were compared with those from the UK Biobank (499,808 participants; years of baseline surveys: 2006-2010; latest mortality follow-up: November 2013; 7995 deaths). Cumulative survival was estimated by applying calculated age-specific HRs for mortality to contemporary US age-specific death rates.</AbstractText>
<AbstractText Label="EXPOSURES" NlmCategory="METHODS">A history of 2 or more of the following: diabetes mellitus, stroke, myocardial infarction (MI).</AbstractText>
<AbstractText Label="MAIN OUTCOMES AND MEASURES" NlmCategory="METHODS">All-cause mortality and estimated reductions in life expectancy.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In participants in the Emerging Risk Factors Collaboration without a history of diabetes, stroke, or MI at baseline (reference group), the all-cause mortality rate adjusted to the age of 60 years was 6.8 per 1000 person-years. Mortality rates per 1000 person-years were 15.6 in participants with a history of diabetes, 16.1 in those with stroke, 16.8 in those with MI, 32.0 in those with both diabetes and MI, 32.5 in those with both diabetes and stroke, 32.8 in those with both stroke and MI, and 59.5 in those with diabetes, stroke, and MI. Compared with the reference group, the HRs for all-cause mortality were 1.9 (95% CI, 1.8-2.0) in participants with a history of diabetes, 2.1 (95% CI, 2.0-2.2) in those with stroke, 2.0 (95% CI, 1.9-2.2) in those with MI, 3.7 (95% CI, 3.3-4.1) in those with both diabetes and MI, 3.8 (95% CI, 3.5-4.2) in those with both diabetes and stroke, 3.5 (95% CI, 3.1-4.0) in those with both stroke and MI, and 6.9 (95% CI, 5.7-8.3) in those with diabetes, stroke, and MI. The HRs from the Emerging Risk Factors Collaboration were similar to those from the more recently recruited UK Biobank. The HRs were little changed after further adjustment for markers of established intermediate pathways (eg, levels of lipids and blood pressure) and lifestyle factors (eg, smoking, diet). At the age of 60 years, a history of any 2 of these conditions was associated with 12 years of reduced life expectancy and a history of all 3 of these conditions was associated with 15 years of reduced life expectancy.</AbstractText>
<AbstractText Label="CONCLUSIONS AND RELEVANCE" NlmCategory="CONCLUSIONS">Mortality associated with a history of diabetes, stroke, or MI was similar for each condition. Because any combination of these conditions was associated with multiplicative mortality risk, life expectancy was substantially lower in people with multimorbidity.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><CollectiveName>Emerging Risk Factors Collaboration</CollectiveName>
</Author>
<Author ValidYN="Y"><LastName>Di Angelantonio</LastName>
<ForeName>Emanuele</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kaptoge</LastName>
<ForeName>Stephen</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wormser</LastName>
<ForeName>David</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Willeit</LastName>
<ForeName>Peter</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Butterworth</LastName>
<ForeName>Adam S</ForeName>
<Initials>AS</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bansal</LastName>
<ForeName>Narinder</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>O'Keeffe</LastName>
<ForeName>Linda M</ForeName>
<Initials>LM</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gao</LastName>
<ForeName>Pei</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wood</LastName>
<ForeName>Angela M</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Burgess</LastName>
<ForeName>Stephen</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Freitag</LastName>
<ForeName>Daniel F</ForeName>
<Initials>DF</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pennells</LastName>
<ForeName>Lisa</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Peters</LastName>
<ForeName>Sanne A</ForeName>
<Initials>SA</Initials>
<AffiliationInfo><Affiliation>University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hart</LastName>
<ForeName>Carole L</ForeName>
<Initials>CL</Initials>
<AffiliationInfo><Affiliation>University of Glasgow, Glasgow, Scotland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Håheim</LastName>
<ForeName>Lise Lund</ForeName>
<Initials>LL</Initials>
<AffiliationInfo><Affiliation>University of Oslo, Oslo, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gillum</LastName>
<ForeName>Richard F</ForeName>
<Initials>RF</Initials>
<AffiliationInfo><Affiliation>Howard University College of Medicine, Washington, DC.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nordestgaard</LastName>
<ForeName>Børge G</ForeName>
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<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2007 Aug 25;370(9588):667-75</RefSource>
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<CommentsCorrections RefType="Cites"><RefSource>PLoS Med. 2015 Mar;12(3):e1001779</RefSource>
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</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Eur J Epidemiol. 2007;22(12):839-69</RefSource>
<PMID Version="1">17876711</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Circulation. 2008 Apr 15;117(15):1945-54</RefSource>
<PMID Version="1">18378618</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2009 Oct 24;374(9699):1421-2</RefSource>
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<CommentsCorrections RefType="Cites"><RefSource>Stat Med. 2010 May 30;29(12):1282-97</RefSource>
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<CommentsCorrections RefType="Cites"><RefSource>Am J Med. 2010 Jun;123(6):556.e1-9</RefSource>
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<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2010 Jun 26;375(9733):2215-22</RefSource>
<PMID Version="1">20609967</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="ErratumIn"><RefSource>JAMA. 2015 Sep 15;314(11):1179</RefSource>
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   |texte=   Association of Cardiometabolic Multimorbidity With Mortality.
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	Serveur d'exploration sur les relations entre la France et l'Australie
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Serveur d'exploration sur les relations entre la France et l'Australie

Association of Cardiometabolic Multimorbidity With Mortality.

Association of Cardiometabolic Multimorbidity With Mortality.

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