The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Identifieur interne : 002764 ( PubMed/Curation ); précédent : 002763; suivant : 002765The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Auteurs : Thomas W. Winkler [Allemagne] ; Anne E. Justice [États-Unis] ; Mariaelisa Graff [États-Unis] ; Llilda Barata [États-Unis] ; Mary F. Feitosa [États-Unis] ; Su Chu [États-Unis] ; Jacek Czajkowski [États-Unis] ; T Nu Esko [États-Unis] ; Tove Fall [Suède] ; Tuomas O. Kilpel Inen [Royaume-Uni] ; Yingchang Lu [États-Unis] ; Reedik M Gi [Royaume-Uni] ; Evelin Mihailov [Estonie] ; Tune H. Pers [États-Unis] ; Sina Rüeger [Suisse] ; Alexander Teumer [Allemagne] ; Georg B. Ehret [États-Unis] ; Teresa Ferreira [Royaume-Uni] ; Nancy L. Heard-Costa [États-Unis] ; Juha Karjalainen [Pays-Bas] ; Vasiliki Lagou [Royaume-Uni] ; Anubha Mahajan [Royaume-Uni] ; Michael D. Neinast [États-Unis] ; Inga Prokopenko [Royaume-Uni] ; Jeannette Simino [États-Unis] ; Tanya M. Teslovich [États-Unis] ; Rick Jansen [Pays-Bas] ; Harm-Jan Westra [États-Unis] ; Charles C. White [États-Unis] ; Devin Absher [États-Unis] ; Tarunveer S. Ahluwalia [Danemark] ; Shafqat Ahmad [Suède] ; Eva Albrecht [Allemagne] ; Alexessander Couto Alves [Royaume-Uni] ; Jennifer L. Bragg-Gresham [États-Unis] ; Anton J M. De Craen [Pays-Bas] ; Joshua C. Bis [États-Unis] ; Amélie Bonnefond [France] ; Gabrielle Boucher [Canada] ; Gemma Cadby [Australie] ; Yu-Ching Cheng [États-Unis] ; Charleston W K. Chiang [États-Unis] ; Graciela Delgado [Allemagne] ; Ayse Demirkan [Pays-Bas] ; Nicole Dueker [États-Unis] ; Niina Eklund [Finlande] ; Gudny Eiriksdottir [Islande] ; Joel Eriksson [Suède] ; Bjarke Feenstra [Danemark] ; Krista Fischer [Estonie] ; Francesca Frau [Italie] ; Tessel E. Galesloot [Pays-Bas] ; Frank Geller [Danemark] ; Anuj Goel [Royaume-Uni] ; Mathias Gorski [Allemagne] ; Tanja B. Grammer [Allemagne] ; Stefan Gustafsson [Suède] ; Saskia Haitjema [Pays-Bas] ; Jouke-Jan Hottenga [Pays-Bas] ; Jennifer E. Huffman [Royaume-Uni] ; Anne U. Jackson [États-Unis] ; Kevin B. Jacobs [États-Unis] ; Sa Johansson [Suède] ; Marika Kaakinen [Finlande] ; Marcus E. Kleber [Allemagne] ; Jari Lahti [Finlande] ; Irene Mateo Leach [Pays-Bas] ; Benjamin Lehne [Royaume-Uni] ; Youfang Liu [États-Unis] ; Ken Sin Lo [Canada] ; Mattias Lorentzon [Suède] ; Jian'An Luan [Royaume-Uni] ; Pamela A F. Madden [États-Unis] ; Massimo Mangino [Royaume-Uni] ; Barbara Mcknight [États-Unis] ; Carolina Medina-Gomez [Pays-Bas] ; Keri L. Monda [États-Unis] ; May E. Montasser [États-Unis] ; Gabriele Müller [Allemagne] ; Martina Müller-Nurasyid [Allemagne] ; Ilja M. Nolte [Pays-Bas] ; Kalliope Panoutsopoulou [Royaume-Uni] ; Laura Pascoe [Royaume-Uni] ; Lavinia Paternoster [Royaume-Uni] ; Nigel W. Rayner [Royaume-Uni] ; Frida Renström [Suède] ; Federica Rizzi [Italie] ; Lynda M. Rose [États-Unis] ; Kathy A. Ryan [États-Unis] ; Perttu Salo [Finlande] ; Serena Sanna [Italie] ; Hubert Scharnagl [Autriche] ; Jianxin Shi [États-Unis] ; Albert Vernon Smith [Islande] ; Lorraine Southam [Royaume-Uni] ; Alena Stan Ková [Finlande] ; Valgerdur Steinthorsdottir [Islande] ; Rona J. Strawbridge [Suède] ; Yun Ju Sung [États-Unis] ; Ioanna Tachmazidou [Royaume-Uni] ; Toshiko Tanaka [États-Unis] ; Gudmar Thorleifsson [Islande] ; Stella Trompet [Pays-Bas] ; Natalia Pervjakova [Finlande] ; Jonathan P. Tyrer [Royaume-Uni] ; Liesbeth Vandenput [Suède] ; Sander W. Van Der Laan [Pays-Bas] ; Nathalie Van Der Velde [Pays-Bas] ; Jessica Van Setten [Pays-Bas] ; Jana V. Van Vliet-Ostaptchouk [Pays-Bas] ; Niek Verweij [Pays-Bas] ; Efthymia Vlachopoulou [Finlande] ; Lindsay L. Waite [États-Unis] ; Sophie R. Wang [États-Unis] ; Zhaoming Wang [États-Unis] ; Sarah H. Wild [Royaume-Uni] ; Christina Willenborg [Allemagne] ; James F. Wilson [Royaume-Uni] ; Andrew Wong [Royaume-Uni] ; Jian Yang [Australie] ; Loïc Yengo [France] ; Laura M. Yerges-Armstrong [États-Unis] ; Lei Yu [États-Unis] ; Weihua Zhang [Royaume-Uni] ; Jing Hua Zhao [Royaume-Uni] ; Ehm A. Andersson [Danemark] ; Stephan J L. Bakker [Pays-Bas] ; Damiano Baldassarre [Italie] ; Karina Banasik [Danemark] ; Matteo Barcella [Italie] ; Cristina Barlassina [Italie] ; Claire Bellis [Australie] ; Paola Benaglio [Suisse] ; John Blangero [États-Unis] ; Matthias Blüher [Allemagne] ; Fabrice Bonnet [France] ; Lori L. Bonnycastle [États-Unis] ; Heather A. Boyd [Danemark] ; Marcel Bruinenberg [Pays-Bas] ; Aron S. Buchman [États-Unis] ; Harry Campbell [Royaume-Uni] ; Yii-Der Ida Chen [États-Unis] ; Peter S. Chines [États-Unis] ; Simone Claudi-Boehm [Allemagne] ; John Cole [États-Unis] ; Francis S. Collins [États-Unis] ; Eco J C. De Geus [Pays-Bas] ; Lisette C P G M. De Groot [Pays-Bas] ; Maria Dimitriou [Grèce] ; Jubao Duan [États-Unis] ; Stefan Enroth [Suède] ; Elodie Eury [France] ; Aliki-Eleni Farmaki [Grèce] ; Nita G. Forouhi [Royaume-Uni] ; Nele Friedrich [Allemagne] ; Pablo V. Gejman [États-Unis] ; Bruna Gigante [Suède] ; Nicola Glorioso [Italie] ; Alan S. Go [États-Unis] ; Omri Gottesman [États-Unis] ; Jürgen Gr Ler [Allemagne] ; Harald Grallert [Allemagne] ; Niels Grarup [Danemark] ; Yu-Mei Gu [Belgique] ; Linda Broer [Pays-Bas] ; Annelies C. Ham [Pays-Bas] ; Torben Hansen [Danemark] ; Tamara B. Harris [États-Unis] ; Catharina A. Hartman [Pays-Bas] ; Maija Hassinen [Finlande] ; Nicholas Hastie [Royaume-Uni] ; Andrew T. Hattersley [Royaume-Uni] ; Andrew C. Heath [États-Unis] ; Anjali K. Henders [Australie] ; Dena Hernandez [États-Unis] ; Hans Hillege [Pays-Bas] ; Oddgeir Holmen [Norvège] ; Kees G. Hovingh [Pays-Bas] ; Jennie Hui [Australie] ; Lise L. Husemoen [Danemark] ; Nina Hutri-K Hönen [Finlande] ; Pirro G. Hysi [Royaume-Uni] ; Thomas Illig [Allemagne] ; Philip L. De Jager [États-Unis] ; Shapour Jalilzadeh [Royaume-Uni] ; Torben J Rgensen [Danemark] ; J Wouter Jukema [Pays-Bas] ; Markus Juonala [Finlande] ; Stavroula Kanoni [Royaume-Uni] ; Maria Karaleftheri [Grèce] ; Kay Tee Khaw [Royaume-Uni] ; Leena Kinnunen [Finlande] ; Steven J. Kittner [États-Unis] ; Wolfgang Koenig [Allemagne] ; Ivana Kolcic [Croatie] ; Peter Kovacs [Allemagne] ; Nikolaj T. Krarup [Danemark] ; Wolfgang Kratzer [Allemagne] ; Janine Krüger [Allemagne] ; Diana Kuh [Royaume-Uni] ; Meena Kumari [Royaume-Uni] ; Theodosios Kyriakou [Royaume-Uni] ; Claudia Langenberg [Royaume-Uni] ; Lars Lannfelt [Suède] ; Chiara Lanzani [Italie] ; Vaneet Lotay [Canada] ; Lenore J. Launer [États-Unis] ; Karin Leander [Suède] ; Jaana Lindström [Finlande] ; Allan Linneberg [Danemark] ; Yan-Ping Liu [Belgique] ; Stéphane Lobbens [France] ; Robert Luben [Royaume-Uni] ; Valeriya Lyssenko [Suède] ; Satu M Nnistö [Finlande] ; Patrik K. Magnusson [Suède] ; Wendy L. Mcardle [Royaume-Uni] ; Cristina Menni [Royaume-Uni] ; Sigrun Merger [Allemagne] ; Lili Milani [Estonie] ; Grant W. Montgomery [Australie] ; Andrew P. Morris [Royaume-Uni] ; Narisu Narisu [États-Unis] ; Mari Nelis [Estonie] ; Ken K. Ong [Royaume-Uni] ; Aarno Palotie [États-Unis] ; Louis Pérusse [Canada] ; Irene Pichler [Allemagne] ; Maria G. Pilia [Italie] ; Anneli Pouta [Finlande] ; Myriam Rheinberger [Allemagne] ; Rasmus Ribel-Madsen [Danemark] ; Marcus Richards [Royaume-Uni] ; Kenneth M. Rice [États-Unis] ; Treva K. Rice [États-Unis] ; Carlo Rivolta [Suisse] ; Veikko Salomaa [Finlande] ; Alan R. Sanders [États-Unis] ; Mark A. Sarzynski [États-Unis] ; Salome Scholtens [Pays-Bas] ; Robert A. Scott [Royaume-Uni] ; William R. Scott [Royaume-Uni] ; Sylvain Sebert [Finlande] ; Sebanti Sengupta [États-Unis] ; Bengt Sennblad [Suède] ; Thomas Seufferlein [Allemagne] ; Angela Silveira [Suède] ; P Eline Slagboom [Pays-Bas] ; Jan H. Smit [Pays-Bas] ; Thomas H. Spars [Danemark] ; Kathleen Stirrups [Royaume-Uni] ; Ronald P. Stolk [Pays-Bas] ; Heather M. Stringham [États-Unis] ; Morris A. Swertz [Pays-Bas] ; Amy J. Swift [États-Unis] ; Ann-Christine Syv Nen [Suède] ; Sian-Tsung Tan [Royaume-Uni] ; Barbara Thorand [Allemagne] ; Anke Tönjes [Allemagne] ; Angelo Tremblay [Canada] ; Emmanouil Tsafantakis [Grèce] ; Peter J. Van Der Most [Pays-Bas] ; Uwe Völker [Allemagne] ; Marie-Claude Vohl [Canada] ; Judith M. Vonk [Pays-Bas] ; Melanie Waldenberger [Allemagne] ; Ryan W. Walker [États-Unis] ; Roman Wennauer [Allemagne] ; Elisabeth Widén [Finlande] ; Gonneke Willemsen [Pays-Bas] ; Tom Wilsgaard [Norvège] ; Alan F. Wright [Royaume-Uni] ; M Carola Zillikens [Pays-Bas] ; Suzanne C. Van Dijk [Pays-Bas] ; Natasja M. Van Schoor [Pays-Bas] ; Folkert W. Asselbergs [Royaume-Uni] ; Paul I W. De Bakker [Pays-Bas] ; Jacques S. Beckmann [Suisse] ; John Beilby [Australie] ; David A. Bennett [États-Unis] ; Richard N. Bergman [États-Unis] ; Sven Bergmann [Suisse] ; Carsten A. Böger [Allemagne] ; Bernhard O. Boehm [Singapour] ; Eric Boerwinkle [États-Unis] ; Dorret I. Boomsma [Pays-Bas] ; Stefan R. Bornstein [Allemagne] ; Erwin P. Bottinger [États-Unis] ; Claude Bouchard [États-Unis] ; John C. Chambers [Royaume-Uni] ; Stephen J. Chanock [États-Unis] ; Daniel I. Chasman [États-Unis] ; Francesco Cucca [Italie] ; Daniele Cusi [Italie] ; George Dedoussis [Grèce] ; Jeanette Erdmann [Allemagne] ; Johan G. Eriksson [Finlande] ; Denis A. Evans [États-Unis] ; Ulf De Faire [Suède] ; Martin Farrall [Pays-Bas] ; Luigi Ferrucci [États-Unis] ; Ian Ford [Royaume-Uni] ; Lude Franke [Pays-Bas] ; Paul W. Franks [États-Unis] ; Philippe Froguel [France] ; Ron T. Gansevoort [Pays-Bas] ; Christian Gieger [Allemagne] ; Henrik Grönberg [Suède] ; Vilmundur Gudnason [Islande] ; Ulf Gyllensten [Suède] ; Per Hall [Suède] ; Anders Hamsten [Suède] ; Pim Van Der Harst [Pays-Bas] ; Caroline Hayward [Royaume-Uni] ; Markku Heliövaara [Finlande] ; Christian Hengstenberg [Allemagne] ; Andrew A. Hicks [Allemagne] ; Aroon Hingorani [Royaume-Uni] ; Albert Hofman [Pays-Bas] ; Frank Hu [États-Unis] ; Heikki V. Huikuri [Finlande] ; Kristian Hveem [Norvège] ; Alan L. James [Australie] ; Joanne M. Jordan [États-Unis] ; Antti Jula [Finlande] ; Mika K Hönen [Finlande] ; Eero Kajantie [Finlande] ; Sekar Kathiresan [États-Unis] ; Lambertus A L M. Kiemeney [Pays-Bas] ; Mika Kivimaki [Royaume-Uni] ; Paul B. Knekt [Finlande] ; Heikki A. Koistinen [Finlande] ; Jaspal S. Kooner [Royaume-Uni] ; Seppo Koskinen [Finlande] ; Johanna Kuusisto [Finlande] ; Winfried Maerz [Autriche] ; Nicholas G. Martin [Australie] ; Markku Laakso [Finlande] ; Timo A. Lakka [Finlande] ; Terho Lehtim Ki [Finlande] ; Guillaume Lettre [Canada] ; Douglas F. Levinson [États-Unis] ; Lars Lind [Suède] ; Marja-Liisa Lokki [Finlande] ; Pekka M Ntyselk [Finlande] ; Mads Melbye [États-Unis] ; Andres Metspalu [Estonie] ; Braxton D. Mitchell [États-Unis] ; Frans L. Moll [Pays-Bas] ; Jeffrey C. Murray [États-Unis] ; Arthur W. Musk [Australie] ; Markku S. Nieminen [Finlande] ; Inger Nj Lstad [Norvège] ; Claes Ohlsson [Suède] ; Albertine J. Oldehinkel [Pays-Bas] ; Ben A. Oostra [Pays-Bas] ; Lyle J. Palmer [Australie] ; James S. Pankow [États-Unis] ; Gerard Pasterkamp [Pays-Bas] ; Nancy L. Pedersen [Suède] ; Oluf Pedersen [Danemark] ; Brenda W. Penninx [Pays-Bas] ; Markus Perola [Finlande] ; Annette Peters [Allemagne] ; Ozren Polašek [Croatie] ; Peter P. Pramstaller [Italie] ; Bruce M. Psaty [États-Unis] ; Lu Qi [États-Unis] ; Thomas Quertermous [États-Unis] ; Olli T. Raitakari [Finlande] ; Tuomo Rankinen [États-Unis] ; Rainer Rauramaa [Finlande] ; Paul M. Ridker [États-Unis] ; John D. Rioux [Canada] ; Fernando Rivadeneira [Pays-Bas] ; Jerome I. Rotter [États-Unis] ; Igor Rudan [Royaume-Uni] ; Hester M. Den Ruijter [Pays-Bas] ; Juha Saltevo [Finlande] ; Naveed Sattar [Royaume-Uni] ; Heribert Schunkert [Allemagne] ; Peter E H. Schwarz [Allemagne] ; Alan R. Shuldiner [États-Unis] ; Juha Sinisalo [Finlande] ; Harold Snieder [Pays-Bas] ; Thorkild I A. S Rensen [Danemark] ; Tim D. Spector [Royaume-Uni] ; Jan A. Staessen [Pays-Bas] ; Bandinelli Stefania [Italie] ; Unnur Thorsteinsdottir [Islande] ; Michael Stumvoll [Allemagne] ; Jean-Claude Tardif [Canada] ; Elena Tremoli [Italie] ; Jaakko Tuomilehto [Arabie saoudite] ; André G. Uitterlinden [Pays-Bas] ; Matti Uusitupa [Finlande] ; André L M. Verbeek [Pays-Bas] ; Sita H. Vermeulen [Pays-Bas] ; Jorma S. Viikari [Finlande] ; Veronique Vitart [Royaume-Uni] ; Henry Völzke [Allemagne] ; Peter Vollenweider [Suisse] ; Gérard Waeber [Suisse] ; Mark Walker [Royaume-Uni] ; Henri Wallaschofski [Allemagne] ; Nicholas J. Wareham [Royaume-Uni] ; Hugh Watkins [Royaume-Uni] ; Eleftheria Zeggini [Royaume-Uni] ; Aravinda Chakravarti [États-Unis] ; Deborah J. Clegg [États-Unis] ; L Adrienne Cupples [États-Unis] ; Penny Gordon-Larsen [États-Unis] ; Cashell E. Jaquish [États-Unis] ; D C Rao [États-Unis] ; Goncalo R. Abecasis [États-Unis] ; Themistocles L. Assimes [États-Unis] ; Inês Barroso [Royaume-Uni] ; Sonja I. Berndt [États-Unis] ; Michael Boehnke [États-Unis] ; Panos Deloukas [Arabie saoudite] ; Caroline S. Fox [États-Unis] ; Leif C. Groop [Finlande] ; David J. Hunter [États-Unis] ; Erik Ingelsson [États-Unis] ; Robert C. Kaplan [États-Unis] ; Mark I. Mccarthy [Royaume-Uni] ; Karen L. Mohlke [États-Unis] ; Jeffrey R. O'Connell [États-Unis] ; David Schlessinger [États-Unis] ; David P. Strachan [Royaume-Uni] ; Kari Stefansson [Islande] ; Cornelia M. Van Duijn [Pays-Bas] ; Joel N. Hirschhorn [États-Unis] ; Cecilia M. Lindgren [Royaume-Uni] ; Iris M. Heid [Allemagne] ; Kari E. North [États-Unis] ; Ingrid B. Borecki [États-Unis] ; Zoltán Kutalik [Suisse] ; Ruth J F. Loos [États-Unis]Source :
- PLoS genetics [ 1553-7404 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Caractères sexuels, Cartographie chromosomique, Facteurs de l'âge, Femelle, Humains, Indice de masse corporelle, Mensurations corporelles (génétique), Mâle, Polymorphisme de nucléotide simple, Population d'origine européenne, Prédisposition génétique à une maladie, Rapport taille-hanches, Sujet âgé, Étude d'association pangénomique.
- MESH :
- génétique : Mensurations corporelles.
- Adulte, Adulte d'âge moyen, Caractères sexuels, Cartographie chromosomique, Facteurs de l'âge, Femelle, Humains, Indice de masse corporelle, Mâle, Polymorphisme de nucléotide simple, Population d'origine européenne, Prédisposition génétique à une maladie, Rapport taille-hanches, Sujet âgé, Étude d'association pangénomique.
English descriptors
- KwdEn :
- MESH :
Abstract
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age- and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to ~2.8M SNPs with BMI and WHRadjBMI in four strata (men ≤50y, men >50y, women ≤50y, women >50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR<5%) age-specific effects, of which 11 had larger effects in younger (<50y) than in older adults (≥50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may provide further insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.
DOI: 10.1371/journal.pgen.1005378
PubMed: 26426971
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Justice</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Graff, Mariaelisa" sort="Graff, Mariaelisa" uniqKey="Graff M" first="Mariaelisa" last="Graff">Mariaelisa Graff</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Barata, Llilda" sort="Barata, Llilda" uniqKey="Barata L" first="Llilda" last="Barata">Llilda Barata</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F" last="Feitosa">Mary F. Feitosa</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Chu, Su" sort="Chu, Su" uniqKey="Chu S" first="Su" last="Chu">Su Chu</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Czajkowski, Jacek" sort="Czajkowski, Jacek" uniqKey="Czajkowski J" first="Jacek" last="Czajkowski">Jacek Czajkowski</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Department of Genetics, Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Fall, Tove" sort="Fall, Tove" uniqKey="Fall T" first="Tove" last="Fall">Tove Fall</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Kilpel Inen, Tuomas O" sort="Kilpel Inen, Tuomas O" uniqKey="Kilpel Inen T" first="Tuomas O" last="Kilpel Inen">Tuomas O. Kilpel Inen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Lu, Yingchang" sort="Lu, Yingchang" uniqKey="Lu Y" first="Yingchang" last="Lu">Yingchang Lu</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H" last="Pers">Tune H. Pers</name><affiliation wicri:level="1"><nlm:affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Rueger, Sina" sort="Rueger, Sina" uniqKey="Rueger S" first="Sina" last="Rüeger">Sina Rüeger</name><affiliation wicri:level="1"><nlm:affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Ehret, Georg B" sort="Ehret, Georg B" uniqKey="Ehret G" first="Georg B" last="Ehret">Georg B. Ehret</name><affiliation wicri:level="1"><nlm:affiliation>Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva, Switzerland; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva, Switzerland; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Heard Costa, Nancy L" sort="Heard Costa, Nancy L" uniqKey="Heard Costa N" first="Nancy L" last="Heard-Costa">Nancy L. Heard-Costa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Karjalainen, Juha" sort="Karjalainen, Juha" uniqKey="Karjalainen J" first="Juha" last="Karjalainen">Juha Karjalainen</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Neinast, Michael D" sort="Neinast, Michael D" uniqKey="Neinast M" first="Michael D" last="Neinast">Michael D. Neinast</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Hammersmith Hospital, London, United Kingdom; Department of Genomics of Common Diseases, School of Public Health, Imperial College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Hammersmith Hospital, London, United Kingdom; Department of Genomics of Common Diseases, School of Public Health, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Simino, Jeannette" sort="Simino, Jeannette" uniqKey="Simino J" first="Jeannette" last="Simino">Jeannette Simino</name><affiliation wicri:level="1"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Teslovich, Tanya M" sort="Teslovich, Tanya M" uniqKey="Teslovich T" first="Tanya M" last="Teslovich">Tanya M. Teslovich</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Jansen, Rick" sort="Jansen, Rick" uniqKey="Jansen R" first="Rick" last="Jansen">Rick Jansen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="White, Charles C" sort="White, Charles C" uniqKey="White C" first="Charles C" last="White">Charles C. White</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Absher, Devin" sort="Absher, Devin" uniqKey="Absher D" first="Devin" last="Absher">Devin Absher</name><affiliation wicri:level="1"><nlm:affiliation>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama</wicri:regionArea></affiliation></author><author><name sortKey="Ahluwalia, Tarunveer S" sort="Ahluwalia, Tarunveer S" uniqKey="Ahluwalia T" first="Tarunveer S" last="Ahluwalia">Tarunveer S. Ahluwalia</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center A/S, Gentofte, Denmark; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center A/S, Gentofte, Denmark; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Ahmad, Shafqat" sort="Ahmad, Shafqat" uniqKey="Ahmad S" first="Shafqat" last="Ahmad">Shafqat Ahmad</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö</wicri:regionArea></affiliation></author><author><name sortKey="Albrecht, Eva" sort="Albrecht, Eva" uniqKey="Albrecht E" first="Eva" last="Albrecht">Eva Albrecht</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Alves, Alexessander Couto" sort="Alves, Alexessander Couto" uniqKey="Alves A" first="Alexessander Couto" last="Alves">Alexessander Couto Alves</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London</wicri:regionArea></affiliation></author><author><name sortKey="Bragg Gresham, Jennifer L" sort="Bragg Gresham, Jennifer L" uniqKey="Bragg Gresham J" first="Jennifer L" last="Bragg-Gresham">Jennifer L. Bragg-Gresham</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="De Craen, Anton J M" sort="De Craen, Anton J M" uniqKey="De Craen A" first="Anton J M" last="De Craen">Anton J M. De Craen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><affiliation wicri:level="1"><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Bonnefond, Amelie" sort="Bonnefond, Amelie" uniqKey="Bonnefond A" first="Amélie" last="Bonnefond">Amélie Bonnefond</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Boucher, Gabrielle" sort="Boucher, Gabrielle" uniqKey="Boucher G" first="Gabrielle" last="Boucher">Gabrielle Boucher</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Cadby, Gemma" sort="Cadby, Gemma" uniqKey="Cadby G" first="Gemma" last="Cadby">Gemma Cadby</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Cheng, Yu Ching" sort="Cheng, Yu Ching" uniqKey="Cheng Y" first="Yu-Ching" last="Cheng">Yu-Ching Cheng</name><affiliation wicri:level="1"><nlm:affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>VA Maryland Health Care System, Baltimore, Maryland, United States of America; University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Chiang, Charleston W K" sort="Chiang, Charleston W K" uniqKey="Chiang C" first="Charleston W K" last="Chiang">Charleston W K. Chiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Delgado, Graciela" sort="Delgado, Graciela" uniqKey="Delgado G" first="Graciela" last="Delgado">Graciela Delgado</name><affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Demirkan, Ayse" sort="Demirkan, Ayse" uniqKey="Demirkan A" first="Ayse" last="Demirkan">Ayse Demirkan</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Dueker, Nicole" sort="Dueker, Nicole" uniqKey="Dueker N" first="Nicole" last="Dueker">Nicole Dueker</name><affiliation wicri:level="1"><nlm:affiliation>Universiy of Maryland School of Medicine, Department of Epidemiology & Public Health, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Universiy of Maryland School of Medicine, Department of Epidemiology & Public Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Eklund, Niina" sort="Eklund, Niina" uniqKey="Eklund N" first="Niina" last="Eklund">Niina Eklund</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea></affiliation></author><author><name sortKey="Eriksson, Joel" sort="Eriksson, Joel" uniqKey="Eriksson J" first="Joel" last="Eriksson">Joel Eriksson</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea></affiliation></author><author><name sortKey="Feenstra, Bjarke" sort="Feenstra, Bjarke" uniqKey="Feenstra B" first="Bjarke" last="Feenstra">Bjarke Feenstra</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Epidemiology Research, Statens Serum Institut, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Frau, Francesca" sort="Frau, Francesca" uniqKey="Frau F" first="Francesca" last="Frau">Francesca Frau</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano</wicri:regionArea></affiliation></author><author><name sortKey="Galesloot, Tessel E" sort="Galesloot, Tessel E" uniqKey="Galesloot T" first="Tessel E" last="Galesloot">Tessel E. Galesloot</name><affiliation wicri:level="1"><nlm:affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Geller, Frank" sort="Geller, Frank" uniqKey="Geller F" first="Frank" last="Geller">Frank Geller</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Epidemiology Research, Statens Serum Institut, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea></affiliation></author><author><name sortKey="Grammer, Tanja B" sort="Grammer, Tanja B" uniqKey="Grammer T" first="Tanja B" last="Grammer">Tanja B. Grammer</name><affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Gustafsson, Stefan" sort="Gustafsson, Stefan" uniqKey="Gustafsson S" first="Stefan" last="Gustafsson">Stefan Gustafsson</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Haitjema, Saskia" sort="Haitjema, Saskia" uniqKey="Haitjema S" first="Saskia" last="Haitjema">Saskia Haitjema</name><affiliation wicri:level="1"><nlm:affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E" last="Huffman">Jennifer E. Huffman</name><affiliation wicri:level="2"><nlm:affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Jacobs, Kevin B" sort="Jacobs, Kevin B" uniqKey="Jacobs K" first="Kevin B" last="Jacobs">Kevin B. Jacobs</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Johansson, Sa" sort="Johansson, Sa" uniqKey="Johansson " first=" Sa" last="Johansson"> Sa Johansson</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Kaakinen, Marika" sort="Kaakinen, Marika" uniqKey="Kaakinen M" first="Marika" last="Kaakinen">Marika Kaakinen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Kleber, Marcus E" sort="Kleber, Marcus E" uniqKey="Kleber M" first="Marcus E" last="Kleber">Marcus E. Kleber</name><affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name><affiliation wicri:level="1"><nlm:affiliation>Folkhälsan Research Centre, Helsinki, Finland; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Folkhälsan Research Centre, Helsinki, Finland; Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Mateo Leach, Irene" sort="Mateo Leach, Irene" uniqKey="Mateo Leach I" first="Irene" last="Mateo Leach">Irene Mateo Leach</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Lehne, Benjamin" sort="Lehne, Benjamin" uniqKey="Lehne B" first="Benjamin" last="Lehne">Benjamin Lehne</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Youfang" sort="Liu, Youfang" uniqKey="Liu Y" first="Youfang" last="Liu">Youfang Liu</name><affiliation wicri:level="1"><nlm:affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Lo, Ken Sin" sort="Lo, Ken Sin" uniqKey="Lo K" first="Ken Sin" last="Lo">Ken Sin Lo</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Lorentzon, Mattias" sort="Lorentzon, Mattias" uniqKey="Lorentzon M" first="Mattias" last="Lorentzon">Mattias Lorentzon</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea></affiliation></author><author><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Madden, Pamela A F" sort="Madden, Pamela A F" uniqKey="Madden P" first="Pamela A F" last="Madden">Pamela A F. Madden</name><affiliation wicri:level="1"><nlm:affiliation>Washington University Medical School, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Washington University Medical School, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation wicri:level="1"><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Medina Gomez, Carolina" sort="Medina Gomez, Carolina" uniqKey="Medina Gomez C" first="Carolina" last="Medina-Gomez">Carolina Medina-Gomez</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Monda, Keri L" sort="Monda, Keri L" uniqKey="Monda K" first="Keri L" last="Monda">Keri L. Monda</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; The Center for Observational Research, Amgen Inc., Thousand Oaks, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; The Center for Observational Research, Amgen Inc., Thousand Oaks, California</wicri:regionArea></affiliation></author><author><name sortKey="Montasser, May E" sort="Montasser, May E" uniqKey="Montasser M" first="May E" last="Montasser">May E. Montasser</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Muller, Gabriele" sort="Muller, Gabriele" uniqKey="Muller G" first="Gabriele" last="Müller">Gabriele Müller</name><affiliation wicri:level="1"><nlm:affiliation>Center for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Panoutsopoulou, Kalliope" sort="Panoutsopoulou, Kalliope" uniqKey="Panoutsopoulou K" first="Kalliope" last="Panoutsopoulou">Kalliope Panoutsopoulou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Pascoe, Laura" sort="Pascoe, Laura" uniqKey="Pascoe L" first="Laura" last="Pascoe">Laura Pascoe</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cell & Molecular Biosciences, Newcastle University, Newcastle, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cell & Molecular Biosciences, Newcastle University, Newcastle</wicri:regionArea></affiliation></author><author><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Rayner, Nigel W" sort="Rayner, Nigel W" uniqKey="Rayner N" first="Nigel W" last="Rayner">Nigel W. Rayner</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Renstrom, Frida" sort="Renstrom, Frida" uniqKey="Renstrom F" first="Frida" last="Renström">Frida Renström</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö</wicri:regionArea></affiliation></author><author><name sortKey="Rizzi, Federica" sort="Rizzi, Federica" uniqKey="Rizzi F" first="Federica" last="Rizzi">Federica Rizzi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano</wicri:regionArea></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name><affiliation wicri:level="1"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Ryan, Kathy A" sort="Ryan, Kathy A" uniqKey="Ryan K" first="Kathy A" last="Ryan">Kathy A. Ryan</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Salo, Perttu" sort="Salo, Perttu" uniqKey="Salo P" first="Perttu" last="Salo">Perttu Salo</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Sanna, Serena" sort="Sanna, Serena" uniqKey="Sanna S" first="Serena" last="Sanna">Serena Sanna</name><affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato</wicri:regionArea></affiliation></author><author><name sortKey="Scharnagl, Hubert" sort="Scharnagl, Hubert" uniqKey="Scharnagl H" first="Hubert" last="Scharnagl">Hubert Scharnagl</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Shi, Jianxin" sort="Shi, Jianxin" uniqKey="Shi J" first="Jianxin" last="Shi">Jianxin Shi</name><affiliation wicri:level="1"><nlm:affiliation>National Cancer Institute, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Cancer Institute, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Smith, Albert Vernon" sort="Smith, Albert Vernon" uniqKey="Smith A" first="Albert Vernon" last="Smith">Albert Vernon Smith</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Southam, Lorraine" sort="Southam, Lorraine" uniqKey="Southam L" first="Lorraine" last="Southam">Lorraine Southam</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Steinthorsdottir, Valgerdur" sort="Steinthorsdottir, Valgerdur" uniqKey="Steinthorsdottir V" first="Valgerdur" last="Steinthorsdottir">Valgerdur Steinthorsdottir</name><affiliation wicri:level="1"><nlm:affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE Genetics, Amgen inc., Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J" last="Strawbridge">Rona J. Strawbridge</name><affiliation wicri:level="1"><nlm:affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Sung, Yun Ju" sort="Sung, Yun Ju" uniqKey="Sung Y" first="Yun Ju" last="Sung">Yun Ju Sung</name><affiliation wicri:level="1"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Tachmazidou, Ioanna" sort="Tachmazidou, Ioanna" uniqKey="Tachmazidou I" first="Ioanna" last="Tachmazidou">Ioanna Tachmazidou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="1"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><affiliation wicri:level="1"><nlm:affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE Genetics, Amgen inc., Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Pervjakova, Natalia" sort="Pervjakova, Natalia" uniqKey="Pervjakova N" first="Natalia" last="Pervjakova">Natalia Pervjakova</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute of Cell and Molecular Biology, Department of Biotechnology, University of Tartu, Tartu, Estonia; University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute of Cell and Molecular Biology, Department of Biotechnology, University of Tartu, Tartu, Estonia; University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Tyrer, Jonathan P" sort="Tyrer, Jonathan P" uniqKey="Tyrer J" first="Jonathan P" last="Tyrer">Jonathan P. Tyrer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Vandenput, Liesbeth" sort="Vandenput, Liesbeth" uniqKey="Vandenput L" first="Liesbeth" last="Vandenput">Liesbeth Vandenput</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Laan, Sander W" sort="Van Der Laan, Sander W" uniqKey="Van Der Laan S" first="Sander W" last="Van Der Laan">Sander W. Van Der Laan</name><affiliation wicri:level="1"><nlm:affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Velde, Nathalie" sort="Van Der Velde, Nathalie" uniqKey="Van Der Velde N" first="Nathalie" last="Van Der Velde">Nathalie Van Der Velde</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Van Setten, Jessica" sort="Van Setten, Jessica" uniqKey="Van Setten J" first="Jessica" last="Van Setten">Jessica Van Setten</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Genetics, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Van Vliet Ostaptchouk, Jana V" sort="Van Vliet Ostaptchouk, Jana V" uniqKey="Van Vliet Ostaptchouk J" first="Jana V" last="Van Vliet-Ostaptchouk">Jana V. Van Vliet-Ostaptchouk</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Endocrinology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Endocrinology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Vlachopoulou, Efthymia" sort="Vlachopoulou, Efthymia" uniqKey="Vlachopoulou E" first="Efthymia" last="Vlachopoulou">Efthymia Vlachopoulou</name><affiliation wicri:level="1"><nlm:affiliation>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Waite, Lindsay L" sort="Waite, Lindsay L" uniqKey="Waite L" first="Lindsay L" last="Waite">Lindsay L. Waite</name><affiliation wicri:level="1"><nlm:affiliation>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Sophie R" sort="Wang, Sophie R" uniqKey="Wang S" first="Sophie R" last="Wang">Sophie R. Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, United States of America; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, United States of America; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Willenborg, Christina" sort="Willenborg, Christina" uniqKey="Willenborg C" first="Christina" last="Willenborg">Christina Willenborg</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><affiliation wicri:level="1"><nlm:affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health & Ageing at UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Jian" sort="Yang, Jian" uniqKey="Yang J" first="Jian" last="Yang">Jian Yang</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, The University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loïc" last="Yengo">Loïc Yengo</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Yerges Armstrong, Laura M" sort="Yerges Armstrong, Laura M" uniqKey="Yerges Armstrong L" first="Laura M" last="Yerges-Armstrong">Laura M. Yerges-Armstrong</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex</wicri:regionArea></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Andersson, Ehm A" sort="Andersson, Ehm A" uniqKey="Andersson E" first="Ehm A" last="Andersson">Ehm A. Andersson</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Bakker, Stephan J L" sort="Bakker, Stephan J L" uniqKey="Bakker S" first="Stephan J L" last="Bakker">Stephan J L. Bakker</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Baldassarre, Damiano" sort="Baldassarre, Damiano" uniqKey="Baldassarre D" first="Damiano" last="Baldassarre">Damiano Baldassarre</name><affiliation wicri:level="1"><nlm:affiliation>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Banasik, Karina" sort="Banasik, Karina" uniqKey="Banasik K" first="Karina" last="Banasik">Karina Banasik</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Barcella, Matteo" sort="Barcella, Matteo" uniqKey="Barcella M" first="Matteo" last="Barcella">Matteo Barcella</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Barlassina, Cristina" sort="Barlassina, Cristina" uniqKey="Barlassina C" first="Cristina" last="Barlassina">Cristina Barlassina</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Benaglio, Paola" sort="Benaglio, Paola" uniqKey="Benaglio P" first="Paola" last="Benaglio">Paola Benaglio</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America; Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Bluher, Matthias" sort="Bluher, Matthias" uniqKey="Bluher M" first="Matthias" last="Blüher">Matthias Blüher</name><affiliation wicri:level="1"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Bonnet, Fabrice" sort="Bonnet, Fabrice" uniqKey="Bonnet F" first="Fabrice" last="Bonnet">Fabrice Bonnet</name><affiliation wicri:level="1"><nlm:affiliation>University Rennes 1, Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Rennes 1, Rennes</wicri:regionArea></affiliation></author><author><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L" last="Bonnycastle">Lori L. Bonnycastle</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Boyd, Heather A" sort="Boyd, Heather A" uniqKey="Boyd H" first="Heather A" last="Boyd">Heather A. Boyd</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Epidemiology Research, Statens Serum Institut, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Bruinenberg, Marcel" sort="Bruinenberg, Marcel" uniqKey="Bruinenberg M" first="Marcel" last="Bruinenberg">Marcel Bruinenberg</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, The LifeLines Cohort Study, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, The LifeLines Cohort Study, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Buchman, Aron S" sort="Buchman, Aron S" uniqKey="Buchman A" first="Aron S" last="Buchman">Aron S. Buchman</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><affiliation wicri:level="1"><nlm:affiliation>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea></affiliation></author><author><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S" last="Chines">Peter S. Chines</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Claudi Boehm, Simone" sort="Claudi Boehm, Simone" uniqKey="Claudi Boehm S" first="Simone" last="Claudi-Boehm">Simone Claudi-Boehm</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Cole, John" sort="Cole, John" uniqKey="Cole J" first="John" last="Cole">John Cole</name><affiliation wicri:level="1"><nlm:affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S" last="Collins">Francis S. Collins</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="De Groot, Lisette C P G M" sort="De Groot, Lisette C P G M" uniqKey="De Groot L" first="Lisette C P G M" last="De Groot">Lisette C P G M. De Groot</name><affiliation wicri:level="1"><nlm:affiliation>Department of Human Nutrition, Wageningen University, Wageningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Nutrition, Wageningen University, Wageningen</wicri:regionArea></affiliation></author><author><name sortKey="Dimitriou, Maria" sort="Dimitriou, Maria" uniqKey="Dimitriou M" first="Maria" last="Dimitriou">Maria Dimitriou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Department of Dietetics-Nutrition, Harokopio University, Athens</wicri:regionArea></affiliation></author><author><name sortKey="Duan, Jubao" sort="Duan, Jubao" uniqKey="Duan J" first="Jubao" last="Duan">Jubao Duan</name><affiliation wicri:level="1"><nlm:affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Enroth, Stefan" sort="Enroth, Stefan" uniqKey="Enroth S" first="Stefan" last="Enroth">Stefan Enroth</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Farmaki, Aliki Eleni" sort="Farmaki, Aliki Eleni" uniqKey="Farmaki A" first="Aliki-Eleni" last="Farmaki">Aliki-Eleni Farmaki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens</wicri:regionArea></affiliation></author><author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G" last="Forouhi">Nita G. Forouhi</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Friedrich, Nele" sort="Friedrich, Nele" uniqKey="Friedrich N" first="Nele" last="Friedrich">Nele Friedrich</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Gejman, Pablo V" sort="Gejman, Pablo V" uniqKey="Gejman P" first="Pablo V" last="Gejman">Pablo V. Gejman</name><affiliation wicri:level="1"><nlm:affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Glorioso, Nicola" sort="Glorioso, Nicola" uniqKey="Glorioso N" first="Nicola" last="Glorioso">Nicola Glorioso</name><affiliation wicri:level="1"><nlm:affiliation>Hypertension and Related Disease Centre, AOU-University of Sassari, Sassari, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Hypertension and Related Disease Centre, AOU-University of Sassari, Sassari</wicri:regionArea></affiliation></author><author><name sortKey="Go, Alan S" sort="Go, Alan S" uniqKey="Go A" first="Alan S" last="Go">Alan S. Go</name><affiliation wicri:level="1"><nlm:affiliation>Kaiser Permanente, Division of Research, Oakland, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Kaiser Permanente, Division of Research, Oakland, California</wicri:regionArea></affiliation></author><author><name sortKey="Gottesman, Omri" sort="Gottesman, Omri" uniqKey="Gottesman O" first="Omri" last="Gottesman">Omri Gottesman</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Gr Ler, Jurgen" sort="Gr Ler, Jurgen" uniqKey="Gr Ler J" first="Jürgen" last="Gr Ler">Jürgen Gr Ler</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine III, Pathobiochemistry, University of Dresden, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine III, Pathobiochemistry, University of Dresden, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Grarup, Niels" sort="Grarup, Niels" uniqKey="Grarup N" first="Niels" last="Grarup">Niels Grarup</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Gu, Yu Mei" sort="Gu, Yu Mei" uniqKey="Gu Y" first="Yu-Mei" last="Gu">Yu-Mei Gu</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Broer, Linda" sort="Broer, Linda" uniqKey="Broer L" first="Linda" last="Broer">Linda Broer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Ham, Annelies C" sort="Ham, Annelies C" uniqKey="Ham A" first="Annelies C" last="Ham">Annelies C. Ham</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense</wicri:regionArea></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, United States of America; National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, United States of America; National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Hartman, Catharina A" sort="Hartman, Catharina A" uniqKey="Hartman C" first="Catharina A" last="Hartman">Catharina A. Hartman</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Hassinen, Maija" sort="Hassinen, Maija" uniqKey="Hassinen M" first="Maija" last="Hassinen">Maija Hassinen</name><affiliation wicri:level="1"><nlm:affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Hastie, Nicholas" sort="Hastie, Nicholas" uniqKey="Hastie N" first="Nicholas" last="Hastie">Nicholas Hastie</name><affiliation wicri:level="2"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T" last="Hattersley">Andrew T. Hattersley</name><affiliation wicri:level="1"><nlm:affiliation>Institue of Biomedical & Clinical Science, University of Exeter, Exeter, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institue of Biomedical & Clinical Science, University of Exeter, Exeter</wicri:regionArea></affiliation></author><author><name sortKey="Heath, Andrew C" sort="Heath, Andrew C" uniqKey="Heath A" first="Andrew C" last="Heath">Andrew C. Heath</name><affiliation wicri:level="1"><nlm:affiliation>Washington University Medical School, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Washington University Medical School, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Henders, Anjali K" sort="Henders, Anjali K" uniqKey="Henders A" first="Anjali K" last="Henders">Anjali K. Henders</name><affiliation wicri:level="1"><nlm:affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Bergofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Hernandez, Dena" sort="Hernandez, Dena" uniqKey="Hernandez D" first="Dena" last="Hernandez">Dena Hernandez</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Hillege, Hans" sort="Hillege, Hans" uniqKey="Hillege H" first="Hans" last="Hillege">Hans Hillege</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Holmen, Oddgeir" sort="Holmen, Oddgeir" uniqKey="Holmen O" first="Oddgeir" last="Holmen">Oddgeir Holmen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim</wicri:regionArea></affiliation></author><author><name sortKey="Hovingh, Kees G" sort="Hovingh, Kees G" uniqKey="Hovingh K" first="Kees G" last="Hovingh">Kees G. Hovingh</name><affiliation wicri:level="1"><nlm:affiliation>Department Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department Vascular Medicine, Academic Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><affiliation wicri:level="1"><nlm:affiliation>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia; School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia; School of Population Health, University of Western Australia, Nedlands, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Husemoen, Lise L" sort="Husemoen, Lise L" uniqKey="Husemoen L" first="Lise L" last="Husemoen">Lise L. Husemoen</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup</wicri:regionArea></affiliation></author><author><name sortKey="Hutri K Honen, Nina" sort="Hutri K Honen, Nina" uniqKey="Hutri K Honen N" first="Nina" last="Hutri-K Hönen">Nina Hutri-K Hönen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Tampere School of Medicine, Tampere, Finland; Department of Pediatrics,Tampere University Hospital, Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Pediatrics, University of Tampere School of Medicine, Tampere, Finland; Department of Pediatrics,Tampere University Hospital, Tampere</wicri:regionArea></affiliation></author><author><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany; Institute of Human Genetics, Hannover Medical School, Hanover, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany; Institute of Human Genetics, Hannover Medical School, Hanover</wicri:regionArea></affiliation></author><author><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts,United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Jalilzadeh, Shapour" sort="Jalilzadeh, Shapour" uniqKey="Jalilzadeh S" first="Shapour" last="Jalilzadeh">Shapour Jalilzadeh</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="J Rgensen, Torben" sort="J Rgensen, Torben" uniqKey="J Rgensen T" first="Torben" last="J Rgensen">Torben J Rgensen</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, University of Aalborg, Aalborg, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, University of Aalborg, Aalborg</wicri:regionArea></affiliation></author><author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Juonala, Markus" sort="Juonala, Markus" uniqKey="Juonala M" first="Markus" last="Juonala">Markus Juonala</name><affiliation wicri:level="1"><nlm:affiliation>Division of Medicine, Turku University Hospital, Turku, Finland; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Medicine, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Division of Medicine, Turku University Hospital, Turku, Finland; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Medicine, University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Karaleftheri, Maria" sort="Karaleftheri, Maria" uniqKey="Karaleftheri M" first="Maria" last="Karaleftheri">Maria Karaleftheri</name><affiliation wicri:level="1"><nlm:affiliation>Echinos Medical Centre, Echinos, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Echinos Medical Centre, Echinos</wicri:regionArea></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay Tee" last="Khaw">Kay Tee Khaw</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Kinnunen, Leena" sort="Kinnunen, Leena" uniqKey="Kinnunen L" first="Leena" last="Kinnunen">Leena Kinnunen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Health, National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kittner, Steven J" sort="Kittner, Steven J" uniqKey="Kittner S" first="Steven J" last="Kittner">Steven J. Kittner</name><affiliation wicri:level="1"><nlm:affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name><affiliation wicri:level="1"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Krarup, Nikolaj T" sort="Krarup, Nikolaj T" uniqKey="Krarup N" first="Nikolaj T" last="Krarup">Nikolaj T. Krarup</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Kratzer, Wolfgang" sort="Kratzer, Wolfgang" uniqKey="Kratzer W" first="Wolfgang" last="Kratzer">Wolfgang Kratzer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Kruger, Janine" sort="Kruger, Janine" uniqKey="Kruger J" first="Janine" last="Krüger">Janine Krüger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine A, University Medicine Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><affiliation wicri:level="1"><nlm:affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health & Ageing at UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Kyriakou, Theodosios" sort="Kyriakou, Theodosios" uniqKey="Kyriakou T" first="Theodosios" last="Kyriakou">Theodosios Kyriakou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Public Health, UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Public Health, UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Lannfelt, Lars" sort="Lannfelt, Lars" uniqKey="Lannfelt L" first="Lars" last="Lannfelt">Lars Lannfelt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Lanzani, Chiara" sort="Lanzani, Chiara" uniqKey="Lanzani C" first="Chiara" last="Lanzani">Chiara Lanzani</name><affiliation wicri:level="1"><nlm:affiliation>Chair of Nephrology, Università Vita Salute San Raffaele, Segrate (Milan), Italy; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Segrate (Milan), Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Chair of Nephrology, Università Vita Salute San Raffaele, Segrate (Milan), Italy; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Segrate (Milan)</wicri:regionArea></affiliation></author><author><name sortKey="Lotay, Vaneet" sort="Lotay, Vaneet" uniqKey="Lotay V" first="Vaneet" last="Lotay">Vaneet Lotay</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biological Sciences, University of Calgary, Calgary, Alberta</wicri:regionArea></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Lindstrom, Jaana" sort="Lindstrom, Jaana" uniqKey="Lindstrom J" first="Jaana" last="Lindström">Jaana Lindström</name><affiliation wicri:level="1"><nlm:affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Linneberg, Allan" sort="Linneberg, Allan" uniqKey="Linneberg A" first="Allan" last="Linneberg">Allan Linneberg</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Experimental Research, Rigshospitalet, Glostrup</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Yan Ping" sort="Liu, Yan Ping" uniqKey="Liu Y" first="Yan-Ping" last="Liu">Yan-Ping Liu</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Luben, Robert" sort="Luben, Robert" uniqKey="Luben R" first="Robert" last="Luben">Robert Luben</name><affiliation wicri:level="1"><nlm:affiliation>Strangeways Research Laboratory Wort's Causeway, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Strangeways Research Laboratory Wort's Causeway, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name><affiliation wicri:level="1"><nlm:affiliation>Steno Diabetes Center A/S, Gentofte, Denmark; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Steno Diabetes Center A/S, Gentofte, Denmark; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö</wicri:regionArea></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Magnusson, Patrik K" sort="Magnusson, Patrik K" uniqKey="Magnusson P" first="Patrik K" last="Magnusson">Patrik K. Magnusson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name><affiliation wicri:level="1"><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Merger, Sigrun" sort="Merger, Sigrun" uniqKey="Merger S" first="Sigrun" last="Merger">Sigrun Merger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Milani, Lili" sort="Milani, Lili" uniqKey="Milani L" first="Lili" last="Milani">Lili Milani</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation wicri:level="1"><nlm:affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Bergofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P" last="Morris">Andrew P. Morris</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Biostatistics, University of Liverpool, Liverpool</wicri:regionArea></affiliation></author><author><name sortKey="Narisu, Narisu" sort="Narisu, Narisu" uniqKey="Narisu N" first="Narisu" last="Narisu">Narisu Narisu</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Nelis, Mari" sort="Nelis, Mari" uniqKey="Nelis M" first="Mari" last="Nelis">Mari Nelis</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K" last="Ong">Ken K. Ong</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Perusse, Louis" sort="Perusse, Louis" uniqKey="Perusse L" first="Louis" last="Pérusse">Louis Pérusse</name><affiliation wicri:level="1"><nlm:affiliation>Department of Kinesiology, Laval University, Québec City, Québec, Canada; Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Kinesiology, Laval University, Québec City, Québec, Canada; Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Pichler, Irene" sort="Pichler, Irene" uniqKey="Pichler I" first="Irene" last="Pichler">Irene Pichler</name><affiliation wicri:level="1"><nlm:affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Pilia, Maria G" sort="Pilia, Maria G" uniqKey="Pilia M" first="Maria G" last="Pilia">Maria G. Pilia</name><affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato</wicri:regionArea></affiliation></author><author><name sortKey="Pouta, Anneli" sort="Pouta, Anneli" uniqKey="Pouta A" first="Anneli" last="Pouta">Anneli Pouta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Children, Young People and Families, National Institute for Health and Welfare, Helsinki, Finland; Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Children, Young People and Families, National Institute for Health and Welfare, Helsinki, Finland; Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Rheinberger, Myriam" sort="Rheinberger, Myriam" uniqKey="Rheinberger M" first="Myriam" last="Rheinberger">Myriam Rheinberger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea></affiliation></author><author><name sortKey="Ribel Madsen, Rasmus" sort="Ribel Madsen, Rasmus" uniqKey="Ribel Madsen R" first="Rasmus" last="Ribel-Madsen">Rasmus Ribel-Madsen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Richards, Marcus" sort="Richards, Marcus" uniqKey="Richards M" first="Marcus" last="Richards">Marcus Richards</name><affiliation wicri:level="1"><nlm:affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health & Ageing at UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Rice, Kenneth M" sort="Rice, Kenneth M" uniqKey="Rice K" first="Kenneth M" last="Rice">Kenneth M. Rice</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Rice, Treva K" sort="Rice, Treva K" uniqKey="Rice T" first="Treva K" last="Rice">Treva K. Rice</name><affiliation wicri:level="1"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Rivolta, Carlo" sort="Rivolta, Carlo" uniqKey="Rivolta C" first="Carlo" last="Rivolta">Carlo Rivolta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Sanders, Alan R" sort="Sanders, Alan R" uniqKey="Sanders A" first="Alan R" last="Sanders">Alan R. Sanders</name><affiliation wicri:level="1"><nlm:affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Sarzynski, Mark A" sort="Sarzynski, Mark A" uniqKey="Sarzynski M" first="Mark A" last="Sarzynski">Mark A. Sarzynski</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana</wicri:regionArea></affiliation></author><author><name sortKey="Scholtens, Salome" sort="Scholtens, Salome" uniqKey="Scholtens S" first="Salome" last="Scholtens">Salome Scholtens</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A" last="Scott">Robert A. Scott</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Scott, William R" sort="Scott, William R" uniqKey="Scott W" first="William R" last="Scott">William R. Scott</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex</wicri:regionArea></affiliation></author><author><name sortKey="Sebert, Sylvain" sort="Sebert, Sylvain" uniqKey="Sebert S" first="Sylvain" last="Sebert">Sylvain Sebert</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Health Sciences, University of Oulu, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Sengupta, Sebanti" sort="Sengupta, Sebanti" uniqKey="Sengupta S" first="Sebanti" last="Sengupta">Sebanti Sengupta</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name><affiliation wicri:level="1"><nlm:affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Science for Life Laboratory, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Seufferlein, Thomas" sort="Seufferlein, Thomas" uniqKey="Seufferlein T" first="Thomas" last="Seufferlein">Thomas Seufferlein</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Silveira, Angela" sort="Silveira, Angela" uniqKey="Silveira A" first="Angela" last="Silveira">Angela Silveira</name><affiliation wicri:level="1"><nlm:affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Slagboom, P Eline" sort="Slagboom, P Eline" uniqKey="Slagboom P" first="P Eline" last="Slagboom">P Eline Slagboom</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Smit, Jan H" sort="Smit, Jan H" uniqKey="Smit J" first="Jan H" last="Smit">Jan H. Smit</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Spars, Thomas H" sort="Spars, Thomas H" uniqKey="Spars T" first="Thomas H" last="Spars">Thomas H. Spars</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Stolk, Ronald P" sort="Stolk, Ronald P" uniqKey="Stolk R" first="Ronald P" last="Stolk">Ronald P. Stolk</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Stringham, Heather M" sort="Stringham, Heather M" uniqKey="Stringham H" first="Heather M" last="Stringham">Heather M. Stringham</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Swertz, Morris A" sort="Swertz, Morris A" uniqKey="Swertz M" first="Morris A" last="Swertz">Morris A. Swertz</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Swift, Amy J" sort="Swift, Amy J" uniqKey="Swift A" first="Amy J" last="Swift">Amy J. Swift</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Tan, Sian Tsung" sort="Tan, Sian Tsung" uniqKey="Tan S" first="Sian-Tsung" last="Tan">Sian-Tsung Tan</name><affiliation wicri:level="1"><nlm:affiliation>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Thorand, Barbara" sort="Thorand, Barbara" uniqKey="Thorand B" first="Barbara" last="Thorand">Barbara Thorand</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name><affiliation wicri:level="1"><nlm:affiliation>University of Leipzig, Department of Medicine, Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, Department of Medicine, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Tremblay, Angelo" sort="Tremblay, Angelo" uniqKey="Tremblay A" first="Angelo" last="Tremblay">Angelo Tremblay</name><affiliation wicri:level="1"><nlm:affiliation>Department of Kinesiology, Laval University, Québec City, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Kinesiology, Laval University, Québec City, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Tsafantakis, Emmanouil" sort="Tsafantakis, Emmanouil" uniqKey="Tsafantakis E" first="Emmanouil" last="Tsafantakis">Emmanouil Tsafantakis</name><affiliation wicri:level="1"><nlm:affiliation>Anogia Medical Centre, Anogia, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Anogia Medical Centre, Anogia</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Most, Peter J" sort="Van Der Most, Peter J" uniqKey="Van Der Most P" first="Peter J" last="Van Der Most">Peter J. Van Der Most</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name><affiliation wicri:level="1"><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Vohl, Marie Claude" sort="Vohl, Marie Claude" uniqKey="Vohl M" first="Marie-Claude" last="Vohl">Marie-Claude Vohl</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada; School of Nutrition, Laval University, Québec City, Québec,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada; School of Nutrition, Laval University, Québec City, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Vonk, Judith M" sort="Vonk, Judith M" uniqKey="Vonk J" first="Judith M" last="Vonk">Judith M. Vonk</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Walker, Ryan W" sort="Walker, Ryan W" uniqKey="Walker R" first="Ryan W" last="Walker">Ryan W. Walker</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Wennauer, Roman" sort="Wennauer, Roman" uniqKey="Wennauer R" first="Roman" last="Wennauer">Roman Wennauer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Chemistry, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Clinical Chemistry, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Widen, Elisabeth" sort="Widen, Elisabeth" uniqKey="Widen E" first="Elisabeth" last="Widén">Elisabeth Widén</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Wilsgaard, Tom" sort="Wilsgaard, Tom" uniqKey="Wilsgaard T" first="Tom" last="Wilsgaard">Tom Wilsgaard</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø</wicri:regionArea></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation wicri:level="2"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Zillikens, M Carola" sort="Zillikens, M Carola" uniqKey="Zillikens M" first="M Carola" last="Zillikens">M Carola Zillikens</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Van Dijk, Suzanne C" sort="Van Dijk, Suzanne C" uniqKey="Van Dijk S" first="Suzanne C" last="Van Dijk">Suzanne C. Van Dijk</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Van Schoor, Natasja M" sort="Van Schoor, Natasja M" uniqKey="Van Schoor N" first="Natasja M" last="Van Schoor">Natasja M. Van Schoor</name><affiliation wicri:level="1"><nlm:affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; VUMC, Department of Epidemiology and Biostatistics, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; VUMC, Department of Epidemiology and Biostatistics, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W" last="Asselbergs">Folkert W. Asselbergs</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands; Institute of Cardiovascular Science, University College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands; Institute of Cardiovascular Science, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I W" last="De Bakker">Paul I W. De Bakker</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands; Department of Epidemiology, University Medical Center, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands; Department of Epidemiology, University Medical Center, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S" last="Beckmann">Jacques S. Beckmann</name><affiliation wicri:level="1"><nlm:affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><affiliation wicri:level="1"><nlm:affiliation>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N" last="Bergman">Richard N. Bergman</name><affiliation wicri:level="1"><nlm:affiliation>Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name><affiliation wicri:level="1"><nlm:affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Boger, Carsten A" sort="Boger, Carsten A" uniqKey="Boger C" first="Carsten A" last="Böger">Carsten A. Böger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea></affiliation></author><author><name sortKey="Boehm, Bernhard O" sort="Boehm, Bernhard O" uniqKey="Boehm B" first="Bernhard O" last="Boehm">Bernhard O. Boehm</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany; Imperial College London, London, United Kingdom; Lee Kong Chian School of Medicine, Singapore, Singapore; Nanyang Technological University, Singapore, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany; Imperial College London, London, United Kingdom; Lee Kong Chian School of Medicine, Singapore, Singapore; Nanyang Technological University, Singapore</wicri:regionArea></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="1"><nlm:affiliation>Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R" last="Bornstein">Stefan R. Bornstein</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Bottinger, Erwin P" sort="Bottinger, Erwin P" uniqKey="Bottinger E" first="Erwin P" last="Bottinger">Erwin P. Bottinger</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana</wicri:regionArea></affiliation></author><author><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom; Imperial College Healthcare NHS Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><affiliation wicri:level="1"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Cucca, Francesco" sort="Cucca, Francesco" uniqKey="Cucca F" first="Francesco" last="Cucca">Francesco Cucca</name><affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy; University of Sassari, Sassari, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy; University of Sassari, Sassari</wicri:regionArea></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Institute of Biomedical Technologies, National Institute of Research, Segrate-Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan, Italy; Institute of Biomedical Technologies, National Institute of Research, Segrate-Milano</wicri:regionArea></affiliation></author><author><name sortKey="Dedoussis, George" sort="Dedoussis, George" uniqKey="Dedoussis G" first="George" last="Dedoussis">George Dedoussis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens</wicri:regionArea></affiliation></author><author><name sortKey="Erdmann, Jeanette" sort="Erdmann, Jeanette" uniqKey="Erdmann J" first="Jeanette" last="Erdmann">Jeanette Erdmann</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Folkhälsan Research Centre, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Folkhälsan Research Centre, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Evans, Denis A" sort="Evans, Denis A" uniqKey="Evans D" first="Denis A" last="Evans">Denis A. Evans</name><affiliation wicri:level="1"><nlm:affiliation>Rush Institute for Healthy Aging and Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Institute for Healthy Aging and Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Farrall, Martin" sort="Farrall, Martin" uniqKey="Farrall M" first="Martin" last="Farrall">Martin Farrall</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Durrer Center for Cardiogenetic Research, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="1"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name><affiliation wicri:level="1"><nlm:affiliation>Robertson Center for Biostatistics, University of Glasgow, Glasgow, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Robertson Center for Biostatistics, University of Glasgow, Glasgow</wicri:regionArea></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Franks, Paul W" sort="Franks, Paul W" uniqKey="Franks P" first="Paul W" last="Franks">Paul W. Franks</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden; Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden, Umeå, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden; Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden, Umeå, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T" last="Gansevoort">Ron T. Gansevoort</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Gronberg, Henrik" sort="Gronberg, Henrik" uniqKey="Gronberg H" first="Henrik" last="Grönberg">Henrik Grönberg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Gyllensten, Ulf" sort="Gyllensten, Ulf" uniqKey="Gyllensten U" first="Ulf" last="Gyllensten">Ulf Gyllensten</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation wicri:level="1"><nlm:affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="2"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Heliovaara, Markku" sort="Heliovaara, Markku" uniqKey="Heliovaara M" first="Markku" last="Heliövaara">Markku Heliövaara</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Health, National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Hengstenberg, Christian" sort="Hengstenberg, Christian" uniqKey="Hengstenberg C" first="Christian" last="Hengstenberg">Christian Hengstenberg</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München</wicri:regionArea></affiliation></author><author><name sortKey="Hicks, Andrew A" sort="Hicks, Andrew A" uniqKey="Hicks A" first="Andrew A" last="Hicks">Andrew A. Hicks</name><affiliation wicri:level="1"><nlm:affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Hingorani, Aroon" sort="Hingorani, Aroon" uniqKey="Hingorani A" first="Aroon" last="Hingorani">Aroon Hingorani</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiovascular Science, University College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cardiovascular Science, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hu, Frank" sort="Hu, Frank" uniqKey="Hu F" first="Frank" last="Hu">Frank Hu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Huikuri, Heikki V" sort="Huikuri, Heikki V" uniqKey="Huikuri H" first="Heikki V" last="Huikuri">Heikki V. Huikuri</name><affiliation wicri:level="1"><nlm:affiliation>Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim</wicri:regionArea></affiliation></author><author><name sortKey="James, Alan L" sort="James, Alan L" uniqKey="James A" first="Alan L" last="James">Alan L. James</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Jordan, Joanne M" sort="Jordan, Joanne M" uniqKey="Jordan J" first="Joanne M" last="Jordan">Joanne M. Jordan</name><affiliation wicri:level="1"><nlm:affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere</wicri:regionArea></affiliation></author><author><name sortKey="Kajantie, Eero" sort="Kajantie, Eero" uniqKey="Kajantie E" first="Eero" last="Kajantie">Eero Kajantie</name><affiliation wicri:level="1"><nlm:affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Kiemeney, Lambertus A L M" sort="Kiemeney, Lambertus A L M" uniqKey="Kiemeney L" first="Lambertus A L M" last="Kiemeney">Lambertus A L M. Kiemeney</name><affiliation wicri:level="1"><nlm:affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Radboud university medical center, Radboud Institute for Health Sciences, Department of Urology, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Radboud university medical center, Radboud Institute for Health Sciences, Department of Urology, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Knekt, Paul B" sort="Knekt, Paul B" uniqKey="Knekt P" first="Paul B" last="Knekt">Paul B. Knekt</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Koistinen, Heikki A" sort="Koistinen, Heikki A" uniqKey="Koistinen H" first="Heikki A" last="Koistinen">Heikki A. Koistinen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Helsinki, Finland; University of Helsinki and Helsinki University Central Hospital, Department of Medicine and Abdominal Center: Endocrinology, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki, Finland; University of Helsinki and Helsinki University Central Hospital, Department of Medicine and Abdominal Center: Endocrinology, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><affiliation wicri:level="1"><nlm:affiliation>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Koskinen, Seppo" sort="Koskinen, Seppo" uniqKey="Koskinen S" first="Seppo" last="Koskinen">Seppo Koskinen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Health, National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Maerz, Winfried" sort="Maerz, Winfried" uniqKey="Maerz W" first="Winfried" last="Maerz">Winfried Maerz</name><affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation wicri:level="1"><nlm:affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Bergofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Lakka, Timo A" sort="Lakka, Timo A" uniqKey="Lakka T" first="Timo A" last="Lakka">Timo A. Lakka</name><affiliation wicri:level="1"><nlm:affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere</wicri:regionArea></affiliation></author><author><name sortKey="Lettre, Guillaume" sort="Lettre, Guillaume" uniqKey="Lettre G" first="Guillaume" last="Lettre">Guillaume Lettre</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Levinson, Douglas F" sort="Levinson, Douglas F" uniqKey="Levinson D" first="Douglas F" last="Levinson">Douglas F. Levinson</name><affiliation wicri:level="1"><nlm:affiliation>Stanford University, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanford University, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Lokki, Marja Liisa" sort="Lokki, Marja Liisa" uniqKey="Lokki M" first="Marja-Liisa" last="Lokki">Marja-Liisa Lokki</name><affiliation wicri:level="1"><nlm:affiliation>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="M Ntyselk, Pekka" sort="M Ntyselk, Pekka" uniqKey="M Ntyselk P" first="Pekka" last="M Ntyselk">Pekka M Ntyselk</name><affiliation wicri:level="1"><nlm:affiliation>Primary Health Care Unit, Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Primary Health Care Unit, Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland; Primary Health Care Unit, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Mitchell, Braxton D" sort="Mitchell, Braxton D" uniqKey="Mitchell B" first="Braxton D" last="Mitchell">Braxton D. Mitchell</name><affiliation wicri:level="1"><nlm:affiliation>University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Moll, Frans L" sort="Moll, Frans L" uniqKey="Moll F" first="Frans L" last="Moll">Frans L. Moll</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Utrecht, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Murray, Jeffrey C" sort="Murray, Jeffrey C" uniqKey="Murray J" first="Jeffrey C" last="Murray">Jeffrey C. Murray</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pediatrics, University of Iowa, Iowa City, Iowa</wicri:regionArea></affiliation></author><author><name sortKey="Musk, Arthur W" sort="Musk, Arthur W" uniqKey="Musk A" first="Arthur W" last="Musk">Arthur W. Musk</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Nieminen, Markku S" sort="Nieminen, Markku S" uniqKey="Nieminen M" first="Markku S" last="Nieminen">Markku S. Nieminen</name><affiliation wicri:level="1"><nlm:affiliation>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Nj Lstad, Inger" sort="Nj Lstad, Inger" uniqKey="Nj Lstad I" first="Inger" last="Nj Lstad">Inger Nj Lstad</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø</wicri:regionArea></affiliation></author><author><name sortKey="Ohlsson, Claes" sort="Ohlsson, Claes" uniqKey="Ohlsson C" first="Claes" last="Ohlsson">Claes Ohlsson</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea></affiliation></author><author><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J" last="Oldehinkel">Albertine J. Oldehinkel</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center, Interdisciplinary Center Psychopathology and Emotion Regulation, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center, Interdisciplinary Center Psychopathology and Emotion Regulation, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health, University of Adelaide, Adelaide, South Australia, Australia; Robinson Research Institute, University of Adelaide, Adelaide, South Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>School of Public Health, University of Adelaide, Adelaide, South Australia, Australia; Robinson Research Institute, University of Adelaide, Adelaide, South Australia</wicri:regionArea></affiliation></author><author><name sortKey="Pankow, James S" sort="Pankow, James S" uniqKey="Pankow J" first="James S" last="Pankow">James S. Pankow</name><affiliation wicri:level="1"><nlm:affiliation>Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Pasterkamp, Gerard" sort="Pasterkamp, Gerard" uniqKey="Pasterkamp G" first="Gerard" last="Pasterkamp">Gerard Pasterkamp</name><affiliation wicri:level="1"><nlm:affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L" last="Pedersen">Nancy L. Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Pedersen, Oluf" sort="Pedersen, Oluf" uniqKey="Pedersen O" first="Oluf" last="Pedersen">Oluf Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland; Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Pramstaller, Peter P" sort="Pramstaller, Peter P" uniqKey="Pramstaller P" first="Peter P" last="Pramstaller">Peter P. Pramstaller</name><affiliation wicri:level="1"><nlm:affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany; Department of Neurology, General Central Hospital, Bolzano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany; Department of Neurology, General Central Hospital, Bolzano</wicri:regionArea></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="1"><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seatte, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seatte, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Qi, Lu" sort="Qi, Lu" uniqKey="Qi L" first="Lu" last="Qi">Lu Qi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Quertermous, Thomas" sort="Quertermous, Thomas" uniqKey="Quertermous T" first="Thomas" last="Quertermous">Thomas Quertermous</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Stanford University School of Medicine, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T" last="Raitakari">Olli T. Raitakari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Rankinen, Tuomo" sort="Rankinen, Tuomo" uniqKey="Rankinen T" first="Tuomo" last="Rankinen">Tuomo Rankinen</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana</wicri:regionArea></affiliation></author><author><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name><affiliation wicri:level="1"><nlm:affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><affiliation wicri:level="1"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Rioux, John D" sort="Rioux, John D" uniqKey="Rioux J" first="John D" last="Rioux">John D. Rioux</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="1"><nlm:affiliation>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Den Ruijter, Hester M" sort="Den Ruijter, Hester M" uniqKey="Den Ruijter H" first="Hester M" last="Den Ruijter">Hester M. Den Ruijter</name><affiliation wicri:level="1"><nlm:affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Saltevo, Juha" sort="Saltevo, Juha" uniqKey="Saltevo J" first="Juha" last="Saltevo">Juha Saltevo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, Central Finland Central Hospital, Jyväskylä</wicri:regionArea></affiliation></author><author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name><affiliation wicri:level="1"><nlm:affiliation>BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow</wicri:regionArea></affiliation></author><author><name sortKey="Schunkert, Heribert" sort="Schunkert, Heribert" uniqKey="Schunkert H" first="Heribert" last="Schunkert">Heribert Schunkert</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München</wicri:regionArea></affiliation></author><author><name sortKey="Schwarz, Peter E H" sort="Schwarz, Peter E H" uniqKey="Schwarz P" first="Peter E H" last="Schwarz">Peter E H. Schwarz</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Sinisalo, Juha" sort="Sinisalo, Juha" uniqKey="Sinisalo J" first="Juha" last="Sinisalo">Juha Sinisalo</name><affiliation wicri:level="1"><nlm:affiliation>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="S Rensen, Thorkild I A" sort="S Rensen, Thorkild I A" uniqKey="S Rensen T" first="Thorkild I A" last="S Rensen">Thorkild I A. S Rensen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg</wicri:regionArea></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Staessen, Jan A" sort="Staessen, Jan A" uniqKey="Staessen J" first="Jan A" last="Staessen">Jan A. Staessen</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; R & D VitaK Group, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; R & D VitaK Group, Maastricht University, Maastricht</wicri:regionArea></affiliation></author><author><name sortKey="Stefania, Bandinelli" sort="Stefania, Bandinelli" uniqKey="Stefania B" first="Bandinelli" last="Stefania">Bandinelli Stefania</name><affiliation wicri:level="1"><nlm:affiliation>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence</wicri:regionArea></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation wicri:level="1"><nlm:affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><affiliation wicri:level="1"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Tardif, Jean Claude" sort="Tardif, Jean Claude" uniqKey="Tardif J" first="Jean-Claude" last="Tardif">Jean-Claude Tardif</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Tremoli, Elena" sort="Tremoli, Elena" uniqKey="Tremoli E" first="Elena" last="Tremoli">Elena Tremoli</name><affiliation wicri:level="1"><nlm:affiliation>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><affiliation wicri:level="1"><nlm:affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria; Instituto de Investigacion Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Spain; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria; Instituto de Investigacion Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Spain; Diabetes Research Group, King Abdulaziz University, Jeddah</wicri:regionArea></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Uusitupa, Matti" sort="Uusitupa, Matti" uniqKey="Uusitupa M" first="Matti" last="Uusitupa">Matti Uusitupa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Research Unit, Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Research Unit, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Verbeek, Andre L M" sort="Verbeek, Andre L M" uniqKey="Verbeek A" first="André L M" last="Verbeek">André L M. Verbeek</name><affiliation wicri:level="1"><nlm:affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Vermeulen, Sita H" sort="Vermeulen, Sita H" uniqKey="Vermeulen S" first="Sita H" last="Vermeulen">Sita H. Vermeulen</name><affiliation wicri:level="1"><nlm:affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Department of Human Genetics, Radboud university medical center, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Department of Human Genetics, Radboud university medical center, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Viikari, Jorma S" sort="Viikari, Jorma S" uniqKey="Viikari J" first="Jorma S" last="Viikari">Jorma S. Viikari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation wicri:level="2"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gérard" last="Waeber">Gérard Waeber</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Walker, Mark" sort="Walker, Mark" uniqKey="Walker M" first="Mark" last="Walker">Mark Walker</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Institute of Cellular Medicine, Newcastle University, Newcastle</wicri:regionArea></affiliation></author><author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Zeggini, Eleftheria" sort="Zeggini, Eleftheria" uniqKey="Zeggini E" first="Eleftheria" last="Zeggini">Eleftheria Zeggini</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Chakravarti, Aravinda" sort="Chakravarti, Aravinda" uniqKey="Chakravarti A" first="Aravinda" last="Chakravarti">Aravinda Chakravarti</name><affiliation wicri:level="1"><nlm:affiliation>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Clegg, Deborah J" sort="Clegg, Deborah J" uniqKey="Clegg D" first="Deborah J" last="Clegg">Deborah J. Clegg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Cupples, L Adrienne" sort="Cupples, L Adrienne" uniqKey="Cupples L" first="L Adrienne" last="Cupples">L Adrienne Cupples</name><affiliation wicri:level="1"><nlm:affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Gordon Larsen, Penny" sort="Gordon Larsen, Penny" uniqKey="Gordon Larsen P" first="Penny" last="Gordon-Larsen">Penny Gordon-Larsen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Jaquish, Cashell E" sort="Jaquish, Cashell E" uniqKey="Jaquish C" first="Cashell E" last="Jaquish">Cashell E. Jaquish</name><affiliation wicri:level="1"><nlm:affiliation>National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Rao, D C" sort="Rao, D C" uniqKey="Rao D" first="D C" last="Rao">D C Rao</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Goncalo R" last="Abecasis">Goncalo R. Abecasis</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Assimes, Themistocles L" sort="Assimes, Themistocles L" uniqKey="Assimes T" first="Themistocles L" last="Assimes">Themistocles L. Assimes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Stanford University School of Medicine, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I" last="Berndt">Sonja I. Berndt</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah</wicri:regionArea></affiliation></author><author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S" last="Fox">Caroline S. Fox</name><affiliation wicri:level="1"><nlm:affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Groop, Leif C" sort="Groop, Leif C" uniqKey="Groop L" first="Leif C" last="Groop">Leif C. Groop</name><affiliation wicri:level="1"><nlm:affiliation>Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Kaplan, Robert C" sort="Kaplan, Robert C" uniqKey="Kaplan R" first="Robert C" last="Kaplan">Robert C. Kaplan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York</wicri:regionArea></affiliation></author><author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L" last="Mohlke">Karen L. Mohlke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R" last="O'Connell">Jeffrey R. O'Connell</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Schlessinger, David" sort="Schlessinger, David" uniqKey="Schlessinger D" first="David" last="Schlessinger">David Schlessinger</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, St George's, University of London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Population Health Research Institute, St George's, University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation wicri:level="1"><nlm:affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Center for Medical Systems Biology, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Center for Medical Systems Biology, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N" last="Hirschhorn">Joel N. Hirschhorn</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M" last="Lindgren">Cecilia M. Lindgren</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M" last="Heid">Iris M. Heid</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name><affiliation wicri:level="1"><nlm:affiliation>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B" last="Borecki">Ingrid B. Borecki</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltán" last="Kutalik">Zoltán Kutalik</name><affiliation wicri:level="1"><nlm:affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26426971</idno><idno type="pmid">26426971</idno><idno type="doi">10.1371/journal.pgen.1005378</idno><idno type="wicri:Area/PubMed/Corpus">002833</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002833</idno><idno type="wicri:Area/PubMed/Curation">002764</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002764</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.</title><author><name sortKey="Winkler, Thomas W" sort="Winkler, Thomas W" uniqKey="Winkler T" first="Thomas W" last="Winkler">Thomas W. Winkler</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg</wicri:regionArea></affiliation></author><author><name sortKey="Justice, Anne E" sort="Justice, Anne E" uniqKey="Justice A" first="Anne E" last="Justice">Anne E. Justice</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Graff, Mariaelisa" sort="Graff, Mariaelisa" uniqKey="Graff M" first="Mariaelisa" last="Graff">Mariaelisa Graff</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Barata, Llilda" sort="Barata, Llilda" uniqKey="Barata L" first="Llilda" last="Barata">Llilda Barata</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F" last="Feitosa">Mary F. Feitosa</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Chu, Su" sort="Chu, Su" uniqKey="Chu S" first="Su" last="Chu">Su Chu</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Czajkowski, Jacek" sort="Czajkowski, Jacek" uniqKey="Czajkowski J" first="Jacek" last="Czajkowski">Jacek Czajkowski</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Department of Genetics, Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Fall, Tove" sort="Fall, Tove" uniqKey="Fall T" first="Tove" last="Fall">Tove Fall</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Kilpel Inen, Tuomas O" sort="Kilpel Inen, Tuomas O" uniqKey="Kilpel Inen T" first="Tuomas O" last="Kilpel Inen">Tuomas O. Kilpel Inen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Lu, Yingchang" sort="Lu, Yingchang" uniqKey="Lu Y" first="Yingchang" last="Lu">Yingchang Lu</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H" last="Pers">Tune H. Pers</name><affiliation wicri:level="1"><nlm:affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Rueger, Sina" sort="Rueger, Sina" uniqKey="Rueger S" first="Sina" last="Rüeger">Sina Rüeger</name><affiliation wicri:level="1"><nlm:affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Ehret, Georg B" sort="Ehret, Georg B" uniqKey="Ehret G" first="Georg B" last="Ehret">Georg B. Ehret</name><affiliation wicri:level="1"><nlm:affiliation>Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva, Switzerland; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva, Switzerland; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Heard Costa, Nancy L" sort="Heard Costa, Nancy L" uniqKey="Heard Costa N" first="Nancy L" last="Heard-Costa">Nancy L. Heard-Costa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Karjalainen, Juha" sort="Karjalainen, Juha" uniqKey="Karjalainen J" first="Juha" last="Karjalainen">Juha Karjalainen</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Neinast, Michael D" sort="Neinast, Michael D" uniqKey="Neinast M" first="Michael D" last="Neinast">Michael D. Neinast</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Hammersmith Hospital, London, United Kingdom; Department of Genomics of Common Diseases, School of Public Health, Imperial College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Hammersmith Hospital, London, United Kingdom; Department of Genomics of Common Diseases, School of Public Health, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Simino, Jeannette" sort="Simino, Jeannette" uniqKey="Simino J" first="Jeannette" last="Simino">Jeannette Simino</name><affiliation wicri:level="1"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Teslovich, Tanya M" sort="Teslovich, Tanya M" uniqKey="Teslovich T" first="Tanya M" last="Teslovich">Tanya M. Teslovich</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Jansen, Rick" sort="Jansen, Rick" uniqKey="Jansen R" first="Rick" last="Jansen">Rick Jansen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="White, Charles C" sort="White, Charles C" uniqKey="White C" first="Charles C" last="White">Charles C. White</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Absher, Devin" sort="Absher, Devin" uniqKey="Absher D" first="Devin" last="Absher">Devin Absher</name><affiliation wicri:level="1"><nlm:affiliation>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama</wicri:regionArea></affiliation></author><author><name sortKey="Ahluwalia, Tarunveer S" sort="Ahluwalia, Tarunveer S" uniqKey="Ahluwalia T" first="Tarunveer S" last="Ahluwalia">Tarunveer S. Ahluwalia</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center A/S, Gentofte, Denmark; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center A/S, Gentofte, Denmark; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Ahmad, Shafqat" sort="Ahmad, Shafqat" uniqKey="Ahmad S" first="Shafqat" last="Ahmad">Shafqat Ahmad</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö</wicri:regionArea></affiliation></author><author><name sortKey="Albrecht, Eva" sort="Albrecht, Eva" uniqKey="Albrecht E" first="Eva" last="Albrecht">Eva Albrecht</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Alves, Alexessander Couto" sort="Alves, Alexessander Couto" uniqKey="Alves A" first="Alexessander Couto" last="Alves">Alexessander Couto Alves</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London</wicri:regionArea></affiliation></author><author><name sortKey="Bragg Gresham, Jennifer L" sort="Bragg Gresham, Jennifer L" uniqKey="Bragg Gresham J" first="Jennifer L" last="Bragg-Gresham">Jennifer L. Bragg-Gresham</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="De Craen, Anton J M" sort="De Craen, Anton J M" uniqKey="De Craen A" first="Anton J M" last="De Craen">Anton J M. De Craen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><affiliation wicri:level="1"><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Bonnefond, Amelie" sort="Bonnefond, Amelie" uniqKey="Bonnefond A" first="Amélie" last="Bonnefond">Amélie Bonnefond</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Boucher, Gabrielle" sort="Boucher, Gabrielle" uniqKey="Boucher G" first="Gabrielle" last="Boucher">Gabrielle Boucher</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Cadby, Gemma" sort="Cadby, Gemma" uniqKey="Cadby G" first="Gemma" last="Cadby">Gemma Cadby</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Cheng, Yu Ching" sort="Cheng, Yu Ching" uniqKey="Cheng Y" first="Yu-Ching" last="Cheng">Yu-Ching Cheng</name><affiliation wicri:level="1"><nlm:affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>VA Maryland Health Care System, Baltimore, Maryland, United States of America; University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Chiang, Charleston W K" sort="Chiang, Charleston W K" uniqKey="Chiang C" first="Charleston W K" last="Chiang">Charleston W K. Chiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Delgado, Graciela" sort="Delgado, Graciela" uniqKey="Delgado G" first="Graciela" last="Delgado">Graciela Delgado</name><affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Demirkan, Ayse" sort="Demirkan, Ayse" uniqKey="Demirkan A" first="Ayse" last="Demirkan">Ayse Demirkan</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Dueker, Nicole" sort="Dueker, Nicole" uniqKey="Dueker N" first="Nicole" last="Dueker">Nicole Dueker</name><affiliation wicri:level="1"><nlm:affiliation>Universiy of Maryland School of Medicine, Department of Epidemiology & Public Health, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Universiy of Maryland School of Medicine, Department of Epidemiology & Public Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Eklund, Niina" sort="Eklund, Niina" uniqKey="Eklund N" first="Niina" last="Eklund">Niina Eklund</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea></affiliation></author><author><name sortKey="Eriksson, Joel" sort="Eriksson, Joel" uniqKey="Eriksson J" first="Joel" last="Eriksson">Joel Eriksson</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea></affiliation></author><author><name sortKey="Feenstra, Bjarke" sort="Feenstra, Bjarke" uniqKey="Feenstra B" first="Bjarke" last="Feenstra">Bjarke Feenstra</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Epidemiology Research, Statens Serum Institut, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Frau, Francesca" sort="Frau, Francesca" uniqKey="Frau F" first="Francesca" last="Frau">Francesca Frau</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano</wicri:regionArea></affiliation></author><author><name sortKey="Galesloot, Tessel E" sort="Galesloot, Tessel E" uniqKey="Galesloot T" first="Tessel E" last="Galesloot">Tessel E. Galesloot</name><affiliation wicri:level="1"><nlm:affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Geller, Frank" sort="Geller, Frank" uniqKey="Geller F" first="Frank" last="Geller">Frank Geller</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Epidemiology Research, Statens Serum Institut, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea></affiliation></author><author><name sortKey="Grammer, Tanja B" sort="Grammer, Tanja B" uniqKey="Grammer T" first="Tanja B" last="Grammer">Tanja B. Grammer</name><affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Gustafsson, Stefan" sort="Gustafsson, Stefan" uniqKey="Gustafsson S" first="Stefan" last="Gustafsson">Stefan Gustafsson</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Haitjema, Saskia" sort="Haitjema, Saskia" uniqKey="Haitjema S" first="Saskia" last="Haitjema">Saskia Haitjema</name><affiliation wicri:level="1"><nlm:affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E" last="Huffman">Jennifer E. Huffman</name><affiliation wicri:level="2"><nlm:affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Jacobs, Kevin B" sort="Jacobs, Kevin B" uniqKey="Jacobs K" first="Kevin B" last="Jacobs">Kevin B. Jacobs</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Johansson, Sa" sort="Johansson, Sa" uniqKey="Johansson " first=" Sa" last="Johansson"> Sa Johansson</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Kaakinen, Marika" sort="Kaakinen, Marika" uniqKey="Kaakinen M" first="Marika" last="Kaakinen">Marika Kaakinen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Kleber, Marcus E" sort="Kleber, Marcus E" uniqKey="Kleber M" first="Marcus E" last="Kleber">Marcus E. Kleber</name><affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name><affiliation wicri:level="1"><nlm:affiliation>Folkhälsan Research Centre, Helsinki, Finland; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Folkhälsan Research Centre, Helsinki, Finland; Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Mateo Leach, Irene" sort="Mateo Leach, Irene" uniqKey="Mateo Leach I" first="Irene" last="Mateo Leach">Irene Mateo Leach</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Lehne, Benjamin" sort="Lehne, Benjamin" uniqKey="Lehne B" first="Benjamin" last="Lehne">Benjamin Lehne</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Youfang" sort="Liu, Youfang" uniqKey="Liu Y" first="Youfang" last="Liu">Youfang Liu</name><affiliation wicri:level="1"><nlm:affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Lo, Ken Sin" sort="Lo, Ken Sin" uniqKey="Lo K" first="Ken Sin" last="Lo">Ken Sin Lo</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Lorentzon, Mattias" sort="Lorentzon, Mattias" uniqKey="Lorentzon M" first="Mattias" last="Lorentzon">Mattias Lorentzon</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea></affiliation></author><author><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Madden, Pamela A F" sort="Madden, Pamela A F" uniqKey="Madden P" first="Pamela A F" last="Madden">Pamela A F. Madden</name><affiliation wicri:level="1"><nlm:affiliation>Washington University Medical School, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Washington University Medical School, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation wicri:level="1"><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Medina Gomez, Carolina" sort="Medina Gomez, Carolina" uniqKey="Medina Gomez C" first="Carolina" last="Medina-Gomez">Carolina Medina-Gomez</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Monda, Keri L" sort="Monda, Keri L" uniqKey="Monda K" first="Keri L" last="Monda">Keri L. Monda</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; The Center for Observational Research, Amgen Inc., Thousand Oaks, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; The Center for Observational Research, Amgen Inc., Thousand Oaks, California</wicri:regionArea></affiliation></author><author><name sortKey="Montasser, May E" sort="Montasser, May E" uniqKey="Montasser M" first="May E" last="Montasser">May E. Montasser</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Muller, Gabriele" sort="Muller, Gabriele" uniqKey="Muller G" first="Gabriele" last="Müller">Gabriele Müller</name><affiliation wicri:level="1"><nlm:affiliation>Center for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Panoutsopoulou, Kalliope" sort="Panoutsopoulou, Kalliope" uniqKey="Panoutsopoulou K" first="Kalliope" last="Panoutsopoulou">Kalliope Panoutsopoulou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Pascoe, Laura" sort="Pascoe, Laura" uniqKey="Pascoe L" first="Laura" last="Pascoe">Laura Pascoe</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cell & Molecular Biosciences, Newcastle University, Newcastle, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cell & Molecular Biosciences, Newcastle University, Newcastle</wicri:regionArea></affiliation></author><author><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Rayner, Nigel W" sort="Rayner, Nigel W" uniqKey="Rayner N" first="Nigel W" last="Rayner">Nigel W. Rayner</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Renstrom, Frida" sort="Renstrom, Frida" uniqKey="Renstrom F" first="Frida" last="Renström">Frida Renström</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö</wicri:regionArea></affiliation></author><author><name sortKey="Rizzi, Federica" sort="Rizzi, Federica" uniqKey="Rizzi F" first="Federica" last="Rizzi">Federica Rizzi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano</wicri:regionArea></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name><affiliation wicri:level="1"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Ryan, Kathy A" sort="Ryan, Kathy A" uniqKey="Ryan K" first="Kathy A" last="Ryan">Kathy A. Ryan</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Salo, Perttu" sort="Salo, Perttu" uniqKey="Salo P" first="Perttu" last="Salo">Perttu Salo</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Sanna, Serena" sort="Sanna, Serena" uniqKey="Sanna S" first="Serena" last="Sanna">Serena Sanna</name><affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato</wicri:regionArea></affiliation></author><author><name sortKey="Scharnagl, Hubert" sort="Scharnagl, Hubert" uniqKey="Scharnagl H" first="Hubert" last="Scharnagl">Hubert Scharnagl</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Shi, Jianxin" sort="Shi, Jianxin" uniqKey="Shi J" first="Jianxin" last="Shi">Jianxin Shi</name><affiliation wicri:level="1"><nlm:affiliation>National Cancer Institute, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Cancer Institute, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Smith, Albert Vernon" sort="Smith, Albert Vernon" uniqKey="Smith A" first="Albert Vernon" last="Smith">Albert Vernon Smith</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Southam, Lorraine" sort="Southam, Lorraine" uniqKey="Southam L" first="Lorraine" last="Southam">Lorraine Southam</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Steinthorsdottir, Valgerdur" sort="Steinthorsdottir, Valgerdur" uniqKey="Steinthorsdottir V" first="Valgerdur" last="Steinthorsdottir">Valgerdur Steinthorsdottir</name><affiliation wicri:level="1"><nlm:affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE Genetics, Amgen inc., Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J" last="Strawbridge">Rona J. Strawbridge</name><affiliation wicri:level="1"><nlm:affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Sung, Yun Ju" sort="Sung, Yun Ju" uniqKey="Sung Y" first="Yun Ju" last="Sung">Yun Ju Sung</name><affiliation wicri:level="1"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Tachmazidou, Ioanna" sort="Tachmazidou, Ioanna" uniqKey="Tachmazidou I" first="Ioanna" last="Tachmazidou">Ioanna Tachmazidou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="1"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><affiliation wicri:level="1"><nlm:affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE Genetics, Amgen inc., Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Pervjakova, Natalia" sort="Pervjakova, Natalia" uniqKey="Pervjakova N" first="Natalia" last="Pervjakova">Natalia Pervjakova</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute of Cell and Molecular Biology, Department of Biotechnology, University of Tartu, Tartu, Estonia; University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute of Cell and Molecular Biology, Department of Biotechnology, University of Tartu, Tartu, Estonia; University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Tyrer, Jonathan P" sort="Tyrer, Jonathan P" uniqKey="Tyrer J" first="Jonathan P" last="Tyrer">Jonathan P. Tyrer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Vandenput, Liesbeth" sort="Vandenput, Liesbeth" uniqKey="Vandenput L" first="Liesbeth" last="Vandenput">Liesbeth Vandenput</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Laan, Sander W" sort="Van Der Laan, Sander W" uniqKey="Van Der Laan S" first="Sander W" last="Van Der Laan">Sander W. Van Der Laan</name><affiliation wicri:level="1"><nlm:affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Velde, Nathalie" sort="Van Der Velde, Nathalie" uniqKey="Van Der Velde N" first="Nathalie" last="Van Der Velde">Nathalie Van Der Velde</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Van Setten, Jessica" sort="Van Setten, Jessica" uniqKey="Van Setten J" first="Jessica" last="Van Setten">Jessica Van Setten</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Genetics, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Van Vliet Ostaptchouk, Jana V" sort="Van Vliet Ostaptchouk, Jana V" uniqKey="Van Vliet Ostaptchouk J" first="Jana V" last="Van Vliet-Ostaptchouk">Jana V. Van Vliet-Ostaptchouk</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Endocrinology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Endocrinology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Vlachopoulou, Efthymia" sort="Vlachopoulou, Efthymia" uniqKey="Vlachopoulou E" first="Efthymia" last="Vlachopoulou">Efthymia Vlachopoulou</name><affiliation wicri:level="1"><nlm:affiliation>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Waite, Lindsay L" sort="Waite, Lindsay L" uniqKey="Waite L" first="Lindsay L" last="Waite">Lindsay L. Waite</name><affiliation wicri:level="1"><nlm:affiliation>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Sophie R" sort="Wang, Sophie R" uniqKey="Wang S" first="Sophie R" last="Wang">Sophie R. Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, United States of America; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, United States of America; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Willenborg, Christina" sort="Willenborg, Christina" uniqKey="Willenborg C" first="Christina" last="Willenborg">Christina Willenborg</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><affiliation wicri:level="1"><nlm:affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health & Ageing at UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Jian" sort="Yang, Jian" uniqKey="Yang J" first="Jian" last="Yang">Jian Yang</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, The University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loïc" last="Yengo">Loïc Yengo</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Yerges Armstrong, Laura M" sort="Yerges Armstrong, Laura M" uniqKey="Yerges Armstrong L" first="Laura M" last="Yerges-Armstrong">Laura M. Yerges-Armstrong</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex</wicri:regionArea></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Andersson, Ehm A" sort="Andersson, Ehm A" uniqKey="Andersson E" first="Ehm A" last="Andersson">Ehm A. Andersson</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Bakker, Stephan J L" sort="Bakker, Stephan J L" uniqKey="Bakker S" first="Stephan J L" last="Bakker">Stephan J L. Bakker</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Baldassarre, Damiano" sort="Baldassarre, Damiano" uniqKey="Baldassarre D" first="Damiano" last="Baldassarre">Damiano Baldassarre</name><affiliation wicri:level="1"><nlm:affiliation>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Banasik, Karina" sort="Banasik, Karina" uniqKey="Banasik K" first="Karina" last="Banasik">Karina Banasik</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Barcella, Matteo" sort="Barcella, Matteo" uniqKey="Barcella M" first="Matteo" last="Barcella">Matteo Barcella</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Barlassina, Cristina" sort="Barlassina, Cristina" uniqKey="Barlassina C" first="Cristina" last="Barlassina">Cristina Barlassina</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Benaglio, Paola" sort="Benaglio, Paola" uniqKey="Benaglio P" first="Paola" last="Benaglio">Paola Benaglio</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America; Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Bluher, Matthias" sort="Bluher, Matthias" uniqKey="Bluher M" first="Matthias" last="Blüher">Matthias Blüher</name><affiliation wicri:level="1"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Bonnet, Fabrice" sort="Bonnet, Fabrice" uniqKey="Bonnet F" first="Fabrice" last="Bonnet">Fabrice Bonnet</name><affiliation wicri:level="1"><nlm:affiliation>University Rennes 1, Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Rennes 1, Rennes</wicri:regionArea></affiliation></author><author><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L" last="Bonnycastle">Lori L. Bonnycastle</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Boyd, Heather A" sort="Boyd, Heather A" uniqKey="Boyd H" first="Heather A" last="Boyd">Heather A. Boyd</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Epidemiology Research, Statens Serum Institut, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Bruinenberg, Marcel" sort="Bruinenberg, Marcel" uniqKey="Bruinenberg M" first="Marcel" last="Bruinenberg">Marcel Bruinenberg</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, The LifeLines Cohort Study, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, The LifeLines Cohort Study, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Buchman, Aron S" sort="Buchman, Aron S" uniqKey="Buchman A" first="Aron S" last="Buchman">Aron S. Buchman</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><affiliation wicri:level="1"><nlm:affiliation>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea></affiliation></author><author><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S" last="Chines">Peter S. Chines</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Claudi Boehm, Simone" sort="Claudi Boehm, Simone" uniqKey="Claudi Boehm S" first="Simone" last="Claudi-Boehm">Simone Claudi-Boehm</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Cole, John" sort="Cole, John" uniqKey="Cole J" first="John" last="Cole">John Cole</name><affiliation wicri:level="1"><nlm:affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S" last="Collins">Francis S. Collins</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="De Groot, Lisette C P G M" sort="De Groot, Lisette C P G M" uniqKey="De Groot L" first="Lisette C P G M" last="De Groot">Lisette C P G M. De Groot</name><affiliation wicri:level="1"><nlm:affiliation>Department of Human Nutrition, Wageningen University, Wageningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Nutrition, Wageningen University, Wageningen</wicri:regionArea></affiliation></author><author><name sortKey="Dimitriou, Maria" sort="Dimitriou, Maria" uniqKey="Dimitriou M" first="Maria" last="Dimitriou">Maria Dimitriou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Department of Dietetics-Nutrition, Harokopio University, Athens</wicri:regionArea></affiliation></author><author><name sortKey="Duan, Jubao" sort="Duan, Jubao" uniqKey="Duan J" first="Jubao" last="Duan">Jubao Duan</name><affiliation wicri:level="1"><nlm:affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Enroth, Stefan" sort="Enroth, Stefan" uniqKey="Enroth S" first="Stefan" last="Enroth">Stefan Enroth</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Farmaki, Aliki Eleni" sort="Farmaki, Aliki Eleni" uniqKey="Farmaki A" first="Aliki-Eleni" last="Farmaki">Aliki-Eleni Farmaki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens</wicri:regionArea></affiliation></author><author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G" last="Forouhi">Nita G. Forouhi</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Friedrich, Nele" sort="Friedrich, Nele" uniqKey="Friedrich N" first="Nele" last="Friedrich">Nele Friedrich</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Gejman, Pablo V" sort="Gejman, Pablo V" uniqKey="Gejman P" first="Pablo V" last="Gejman">Pablo V. Gejman</name><affiliation wicri:level="1"><nlm:affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Glorioso, Nicola" sort="Glorioso, Nicola" uniqKey="Glorioso N" first="Nicola" last="Glorioso">Nicola Glorioso</name><affiliation wicri:level="1"><nlm:affiliation>Hypertension and Related Disease Centre, AOU-University of Sassari, Sassari, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Hypertension and Related Disease Centre, AOU-University of Sassari, Sassari</wicri:regionArea></affiliation></author><author><name sortKey="Go, Alan S" sort="Go, Alan S" uniqKey="Go A" first="Alan S" last="Go">Alan S. Go</name><affiliation wicri:level="1"><nlm:affiliation>Kaiser Permanente, Division of Research, Oakland, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Kaiser Permanente, Division of Research, Oakland, California</wicri:regionArea></affiliation></author><author><name sortKey="Gottesman, Omri" sort="Gottesman, Omri" uniqKey="Gottesman O" first="Omri" last="Gottesman">Omri Gottesman</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Gr Ler, Jurgen" sort="Gr Ler, Jurgen" uniqKey="Gr Ler J" first="Jürgen" last="Gr Ler">Jürgen Gr Ler</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine III, Pathobiochemistry, University of Dresden, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine III, Pathobiochemistry, University of Dresden, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Grarup, Niels" sort="Grarup, Niels" uniqKey="Grarup N" first="Niels" last="Grarup">Niels Grarup</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Gu, Yu Mei" sort="Gu, Yu Mei" uniqKey="Gu Y" first="Yu-Mei" last="Gu">Yu-Mei Gu</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Broer, Linda" sort="Broer, Linda" uniqKey="Broer L" first="Linda" last="Broer">Linda Broer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Ham, Annelies C" sort="Ham, Annelies C" uniqKey="Ham A" first="Annelies C" last="Ham">Annelies C. Ham</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense</wicri:regionArea></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, United States of America; National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, United States of America; National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Hartman, Catharina A" sort="Hartman, Catharina A" uniqKey="Hartman C" first="Catharina A" last="Hartman">Catharina A. Hartman</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Hassinen, Maija" sort="Hassinen, Maija" uniqKey="Hassinen M" first="Maija" last="Hassinen">Maija Hassinen</name><affiliation wicri:level="1"><nlm:affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Hastie, Nicholas" sort="Hastie, Nicholas" uniqKey="Hastie N" first="Nicholas" last="Hastie">Nicholas Hastie</name><affiliation wicri:level="2"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T" last="Hattersley">Andrew T. Hattersley</name><affiliation wicri:level="1"><nlm:affiliation>Institue of Biomedical & Clinical Science, University of Exeter, Exeter, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institue of Biomedical & Clinical Science, University of Exeter, Exeter</wicri:regionArea></affiliation></author><author><name sortKey="Heath, Andrew C" sort="Heath, Andrew C" uniqKey="Heath A" first="Andrew C" last="Heath">Andrew C. Heath</name><affiliation wicri:level="1"><nlm:affiliation>Washington University Medical School, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Washington University Medical School, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Henders, Anjali K" sort="Henders, Anjali K" uniqKey="Henders A" first="Anjali K" last="Henders">Anjali K. Henders</name><affiliation wicri:level="1"><nlm:affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Bergofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Hernandez, Dena" sort="Hernandez, Dena" uniqKey="Hernandez D" first="Dena" last="Hernandez">Dena Hernandez</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Hillege, Hans" sort="Hillege, Hans" uniqKey="Hillege H" first="Hans" last="Hillege">Hans Hillege</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Holmen, Oddgeir" sort="Holmen, Oddgeir" uniqKey="Holmen O" first="Oddgeir" last="Holmen">Oddgeir Holmen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim</wicri:regionArea></affiliation></author><author><name sortKey="Hovingh, Kees G" sort="Hovingh, Kees G" uniqKey="Hovingh K" first="Kees G" last="Hovingh">Kees G. Hovingh</name><affiliation wicri:level="1"><nlm:affiliation>Department Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department Vascular Medicine, Academic Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><affiliation wicri:level="1"><nlm:affiliation>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia; School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia; School of Population Health, University of Western Australia, Nedlands, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Husemoen, Lise L" sort="Husemoen, Lise L" uniqKey="Husemoen L" first="Lise L" last="Husemoen">Lise L. Husemoen</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup</wicri:regionArea></affiliation></author><author><name sortKey="Hutri K Honen, Nina" sort="Hutri K Honen, Nina" uniqKey="Hutri K Honen N" first="Nina" last="Hutri-K Hönen">Nina Hutri-K Hönen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Tampere School of Medicine, Tampere, Finland; Department of Pediatrics,Tampere University Hospital, Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Pediatrics, University of Tampere School of Medicine, Tampere, Finland; Department of Pediatrics,Tampere University Hospital, Tampere</wicri:regionArea></affiliation></author><author><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany; Institute of Human Genetics, Hannover Medical School, Hanover, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany; Institute of Human Genetics, Hannover Medical School, Hanover</wicri:regionArea></affiliation></author><author><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts,United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Jalilzadeh, Shapour" sort="Jalilzadeh, Shapour" uniqKey="Jalilzadeh S" first="Shapour" last="Jalilzadeh">Shapour Jalilzadeh</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="J Rgensen, Torben" sort="J Rgensen, Torben" uniqKey="J Rgensen T" first="Torben" last="J Rgensen">Torben J Rgensen</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, University of Aalborg, Aalborg, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, University of Aalborg, Aalborg</wicri:regionArea></affiliation></author><author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Juonala, Markus" sort="Juonala, Markus" uniqKey="Juonala M" first="Markus" last="Juonala">Markus Juonala</name><affiliation wicri:level="1"><nlm:affiliation>Division of Medicine, Turku University Hospital, Turku, Finland; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Medicine, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Division of Medicine, Turku University Hospital, Turku, Finland; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Medicine, University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Karaleftheri, Maria" sort="Karaleftheri, Maria" uniqKey="Karaleftheri M" first="Maria" last="Karaleftheri">Maria Karaleftheri</name><affiliation wicri:level="1"><nlm:affiliation>Echinos Medical Centre, Echinos, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Echinos Medical Centre, Echinos</wicri:regionArea></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay Tee" last="Khaw">Kay Tee Khaw</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Kinnunen, Leena" sort="Kinnunen, Leena" uniqKey="Kinnunen L" first="Leena" last="Kinnunen">Leena Kinnunen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Health, National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kittner, Steven J" sort="Kittner, Steven J" uniqKey="Kittner S" first="Steven J" last="Kittner">Steven J. Kittner</name><affiliation wicri:level="1"><nlm:affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name><affiliation wicri:level="1"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Krarup, Nikolaj T" sort="Krarup, Nikolaj T" uniqKey="Krarup N" first="Nikolaj T" last="Krarup">Nikolaj T. Krarup</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Kratzer, Wolfgang" sort="Kratzer, Wolfgang" uniqKey="Kratzer W" first="Wolfgang" last="Kratzer">Wolfgang Kratzer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Kruger, Janine" sort="Kruger, Janine" uniqKey="Kruger J" first="Janine" last="Krüger">Janine Krüger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine A, University Medicine Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><affiliation wicri:level="1"><nlm:affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health & Ageing at UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Kyriakou, Theodosios" sort="Kyriakou, Theodosios" uniqKey="Kyriakou T" first="Theodosios" last="Kyriakou">Theodosios Kyriakou</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Public Health, UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Public Health, UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Lannfelt, Lars" sort="Lannfelt, Lars" uniqKey="Lannfelt L" first="Lars" last="Lannfelt">Lars Lannfelt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Lanzani, Chiara" sort="Lanzani, Chiara" uniqKey="Lanzani C" first="Chiara" last="Lanzani">Chiara Lanzani</name><affiliation wicri:level="1"><nlm:affiliation>Chair of Nephrology, Università Vita Salute San Raffaele, Segrate (Milan), Italy; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Segrate (Milan), Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Chair of Nephrology, Università Vita Salute San Raffaele, Segrate (Milan), Italy; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Segrate (Milan)</wicri:regionArea></affiliation></author><author><name sortKey="Lotay, Vaneet" sort="Lotay, Vaneet" uniqKey="Lotay V" first="Vaneet" last="Lotay">Vaneet Lotay</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biological Sciences, University of Calgary, Calgary, Alberta</wicri:regionArea></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Lindstrom, Jaana" sort="Lindstrom, Jaana" uniqKey="Lindstrom J" first="Jaana" last="Lindström">Jaana Lindström</name><affiliation wicri:level="1"><nlm:affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Linneberg, Allan" sort="Linneberg, Allan" uniqKey="Linneberg A" first="Allan" last="Linneberg">Allan Linneberg</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Experimental Research, Rigshospitalet, Glostrup</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Yan Ping" sort="Liu, Yan Ping" uniqKey="Liu Y" first="Yan-Ping" last="Liu">Yan-Ping Liu</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Luben, Robert" sort="Luben, Robert" uniqKey="Luben R" first="Robert" last="Luben">Robert Luben</name><affiliation wicri:level="1"><nlm:affiliation>Strangeways Research Laboratory Wort's Causeway, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Strangeways Research Laboratory Wort's Causeway, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name><affiliation wicri:level="1"><nlm:affiliation>Steno Diabetes Center A/S, Gentofte, Denmark; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Steno Diabetes Center A/S, Gentofte, Denmark; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö</wicri:regionArea></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Magnusson, Patrik K" sort="Magnusson, Patrik K" uniqKey="Magnusson P" first="Patrik K" last="Magnusson">Patrik K. Magnusson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name><affiliation wicri:level="1"><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Merger, Sigrun" sort="Merger, Sigrun" uniqKey="Merger S" first="Sigrun" last="Merger">Sigrun Merger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Milani, Lili" sort="Milani, Lili" uniqKey="Milani L" first="Lili" last="Milani">Lili Milani</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation wicri:level="1"><nlm:affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Bergofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P" last="Morris">Andrew P. Morris</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Biostatistics, University of Liverpool, Liverpool</wicri:regionArea></affiliation></author><author><name sortKey="Narisu, Narisu" sort="Narisu, Narisu" uniqKey="Narisu N" first="Narisu" last="Narisu">Narisu Narisu</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Nelis, Mari" sort="Nelis, Mari" uniqKey="Nelis M" first="Mari" last="Nelis">Mari Nelis</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K" last="Ong">Ken K. Ong</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Perusse, Louis" sort="Perusse, Louis" uniqKey="Perusse L" first="Louis" last="Pérusse">Louis Pérusse</name><affiliation wicri:level="1"><nlm:affiliation>Department of Kinesiology, Laval University, Québec City, Québec, Canada; Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Kinesiology, Laval University, Québec City, Québec, Canada; Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Pichler, Irene" sort="Pichler, Irene" uniqKey="Pichler I" first="Irene" last="Pichler">Irene Pichler</name><affiliation wicri:level="1"><nlm:affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Pilia, Maria G" sort="Pilia, Maria G" uniqKey="Pilia M" first="Maria G" last="Pilia">Maria G. Pilia</name><affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato</wicri:regionArea></affiliation></author><author><name sortKey="Pouta, Anneli" sort="Pouta, Anneli" uniqKey="Pouta A" first="Anneli" last="Pouta">Anneli Pouta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Children, Young People and Families, National Institute for Health and Welfare, Helsinki, Finland; Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Children, Young People and Families, National Institute for Health and Welfare, Helsinki, Finland; Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Rheinberger, Myriam" sort="Rheinberger, Myriam" uniqKey="Rheinberger M" first="Myriam" last="Rheinberger">Myriam Rheinberger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea></affiliation></author><author><name sortKey="Ribel Madsen, Rasmus" sort="Ribel Madsen, Rasmus" uniqKey="Ribel Madsen R" first="Rasmus" last="Ribel-Madsen">Rasmus Ribel-Madsen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Richards, Marcus" sort="Richards, Marcus" uniqKey="Richards M" first="Marcus" last="Richards">Marcus Richards</name><affiliation wicri:level="1"><nlm:affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Unit for Lifelong Health & Ageing at UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Rice, Kenneth M" sort="Rice, Kenneth M" uniqKey="Rice K" first="Kenneth M" last="Rice">Kenneth M. Rice</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Rice, Treva K" sort="Rice, Treva K" uniqKey="Rice T" first="Treva K" last="Rice">Treva K. Rice</name><affiliation wicri:level="1"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Rivolta, Carlo" sort="Rivolta, Carlo" uniqKey="Rivolta C" first="Carlo" last="Rivolta">Carlo Rivolta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Sanders, Alan R" sort="Sanders, Alan R" uniqKey="Sanders A" first="Alan R" last="Sanders">Alan R. Sanders</name><affiliation wicri:level="1"><nlm:affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Sarzynski, Mark A" sort="Sarzynski, Mark A" uniqKey="Sarzynski M" first="Mark A" last="Sarzynski">Mark A. Sarzynski</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana</wicri:regionArea></affiliation></author><author><name sortKey="Scholtens, Salome" sort="Scholtens, Salome" uniqKey="Scholtens S" first="Salome" last="Scholtens">Salome Scholtens</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A" last="Scott">Robert A. Scott</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Scott, William R" sort="Scott, William R" uniqKey="Scott W" first="William R" last="Scott">William R. Scott</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex</wicri:regionArea></affiliation></author><author><name sortKey="Sebert, Sylvain" sort="Sebert, Sylvain" uniqKey="Sebert S" first="Sylvain" last="Sebert">Sylvain Sebert</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Health Sciences, University of Oulu, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Sengupta, Sebanti" sort="Sengupta, Sebanti" uniqKey="Sengupta S" first="Sebanti" last="Sengupta">Sebanti Sengupta</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name><affiliation wicri:level="1"><nlm:affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Science for Life Laboratory, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Seufferlein, Thomas" sort="Seufferlein, Thomas" uniqKey="Seufferlein T" first="Thomas" last="Seufferlein">Thomas Seufferlein</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Silveira, Angela" sort="Silveira, Angela" uniqKey="Silveira A" first="Angela" last="Silveira">Angela Silveira</name><affiliation wicri:level="1"><nlm:affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Slagboom, P Eline" sort="Slagboom, P Eline" uniqKey="Slagboom P" first="P Eline" last="Slagboom">P Eline Slagboom</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Smit, Jan H" sort="Smit, Jan H" uniqKey="Smit J" first="Jan H" last="Smit">Jan H. Smit</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Spars, Thomas H" sort="Spars, Thomas H" uniqKey="Spars T" first="Thomas H" last="Spars">Thomas H. Spars</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Stolk, Ronald P" sort="Stolk, Ronald P" uniqKey="Stolk R" first="Ronald P" last="Stolk">Ronald P. Stolk</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Stringham, Heather M" sort="Stringham, Heather M" uniqKey="Stringham H" first="Heather M" last="Stringham">Heather M. Stringham</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Swertz, Morris A" sort="Swertz, Morris A" uniqKey="Swertz M" first="Morris A" last="Swertz">Morris A. Swertz</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Swift, Amy J" sort="Swift, Amy J" uniqKey="Swift A" first="Amy J" last="Swift">Amy J. Swift</name><affiliation wicri:level="1"><nlm:affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Tan, Sian Tsung" sort="Tan, Sian Tsung" uniqKey="Tan S" first="Sian-Tsung" last="Tan">Sian-Tsung Tan</name><affiliation wicri:level="1"><nlm:affiliation>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Thorand, Barbara" sort="Thorand, Barbara" uniqKey="Thorand B" first="Barbara" last="Thorand">Barbara Thorand</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name><affiliation wicri:level="1"><nlm:affiliation>University of Leipzig, Department of Medicine, Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, Department of Medicine, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Tremblay, Angelo" sort="Tremblay, Angelo" uniqKey="Tremblay A" first="Angelo" last="Tremblay">Angelo Tremblay</name><affiliation wicri:level="1"><nlm:affiliation>Department of Kinesiology, Laval University, Québec City, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Kinesiology, Laval University, Québec City, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Tsafantakis, Emmanouil" sort="Tsafantakis, Emmanouil" uniqKey="Tsafantakis E" first="Emmanouil" last="Tsafantakis">Emmanouil Tsafantakis</name><affiliation wicri:level="1"><nlm:affiliation>Anogia Medical Centre, Anogia, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Anogia Medical Centre, Anogia</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Most, Peter J" sort="Van Der Most, Peter J" uniqKey="Van Der Most P" first="Peter J" last="Van Der Most">Peter J. Van Der Most</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name><affiliation wicri:level="1"><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Vohl, Marie Claude" sort="Vohl, Marie Claude" uniqKey="Vohl M" first="Marie-Claude" last="Vohl">Marie-Claude Vohl</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada; School of Nutrition, Laval University, Québec City, Québec,Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada; School of Nutrition, Laval University, Québec City, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Vonk, Judith M" sort="Vonk, Judith M" uniqKey="Vonk J" first="Judith M" last="Vonk">Judith M. Vonk</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Walker, Ryan W" sort="Walker, Ryan W" uniqKey="Walker R" first="Ryan W" last="Walker">Ryan W. Walker</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Wennauer, Roman" sort="Wennauer, Roman" uniqKey="Wennauer R" first="Roman" last="Wennauer">Roman Wennauer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Chemistry, Ulm University Medical Centre, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Clinical Chemistry, Ulm University Medical Centre, Ulm</wicri:regionArea></affiliation></author><author><name sortKey="Widen, Elisabeth" sort="Widen, Elisabeth" uniqKey="Widen E" first="Elisabeth" last="Widén">Elisabeth Widén</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Wilsgaard, Tom" sort="Wilsgaard, Tom" uniqKey="Wilsgaard T" first="Tom" last="Wilsgaard">Tom Wilsgaard</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø</wicri:regionArea></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation wicri:level="2"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Zillikens, M Carola" sort="Zillikens, M Carola" uniqKey="Zillikens M" first="M Carola" last="Zillikens">M Carola Zillikens</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Van Dijk, Suzanne C" sort="Van Dijk, Suzanne C" uniqKey="Van Dijk S" first="Suzanne C" last="Van Dijk">Suzanne C. Van Dijk</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Van Schoor, Natasja M" sort="Van Schoor, Natasja M" uniqKey="Van Schoor N" first="Natasja M" last="Van Schoor">Natasja M. Van Schoor</name><affiliation wicri:level="1"><nlm:affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; VUMC, Department of Epidemiology and Biostatistics, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; VUMC, Department of Epidemiology and Biostatistics, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W" last="Asselbergs">Folkert W. Asselbergs</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands; Institute of Cardiovascular Science, University College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands; Institute of Cardiovascular Science, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I W" last="De Bakker">Paul I W. De Bakker</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands; Department of Epidemiology, University Medical Center, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands; Department of Epidemiology, University Medical Center, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S" last="Beckmann">Jacques S. Beckmann</name><affiliation wicri:level="1"><nlm:affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><affiliation wicri:level="1"><nlm:affiliation>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N" last="Bergman">Richard N. Bergman</name><affiliation wicri:level="1"><nlm:affiliation>Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name><affiliation wicri:level="1"><nlm:affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Boger, Carsten A" sort="Boger, Carsten A" uniqKey="Boger C" first="Carsten A" last="Böger">Carsten A. Böger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea></affiliation></author><author><name sortKey="Boehm, Bernhard O" sort="Boehm, Bernhard O" uniqKey="Boehm B" first="Bernhard O" last="Boehm">Bernhard O. Boehm</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany; Imperial College London, London, United Kingdom; Lee Kong Chian School of Medicine, Singapore, Singapore; Nanyang Technological University, Singapore, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany; Imperial College London, London, United Kingdom; Lee Kong Chian School of Medicine, Singapore, Singapore; Nanyang Technological University, Singapore</wicri:regionArea></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="1"><nlm:affiliation>Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Bornstein, Stefan R" sort="Bornstein, Stefan R" uniqKey="Bornstein S" first="Stefan R" last="Bornstein">Stefan R. Bornstein</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Bottinger, Erwin P" sort="Bottinger, Erwin P" uniqKey="Bottinger E" first="Erwin P" last="Bottinger">Erwin P. Bottinger</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana</wicri:regionArea></affiliation></author><author><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom; Imperial College Healthcare NHS Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><affiliation wicri:level="1"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Cucca, Francesco" sort="Cucca, Francesco" uniqKey="Cucca F" first="Francesco" last="Cucca">Francesco Cucca</name><affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy; University of Sassari, Sassari, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy; University of Sassari, Sassari</wicri:regionArea></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Institute of Biomedical Technologies, National Institute of Research, Segrate-Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, University of Milan, Milan, Italy; Institute of Biomedical Technologies, National Institute of Research, Segrate-Milano</wicri:regionArea></affiliation></author><author><name sortKey="Dedoussis, George" sort="Dedoussis, George" uniqKey="Dedoussis G" first="George" last="Dedoussis">George Dedoussis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens</wicri:regionArea></affiliation></author><author><name sortKey="Erdmann, Jeanette" sort="Erdmann, Jeanette" uniqKey="Erdmann J" first="Jeanette" last="Erdmann">Jeanette Erdmann</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Folkhälsan Research Centre, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Folkhälsan Research Centre, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Evans, Denis A" sort="Evans, Denis A" uniqKey="Evans D" first="Denis A" last="Evans">Denis A. Evans</name><affiliation wicri:level="1"><nlm:affiliation>Rush Institute for Healthy Aging and Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Institute for Healthy Aging and Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Farrall, Martin" sort="Farrall, Martin" uniqKey="Farrall M" first="Martin" last="Farrall">Martin Farrall</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Durrer Center for Cardiogenetic Research, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="1"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name><affiliation wicri:level="1"><nlm:affiliation>Robertson Center for Biostatistics, University of Glasgow, Glasgow, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Robertson Center for Biostatistics, University of Glasgow, Glasgow</wicri:regionArea></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Franks, Paul W" sort="Franks, Paul W" uniqKey="Franks P" first="Paul W" last="Franks">Paul W. Franks</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden; Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden, Umeå, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden; Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden, Umeå, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille</wicri:regionArea></affiliation></author><author><name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T" last="Gansevoort">Ron T. Gansevoort</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Gronberg, Henrik" sort="Gronberg, Henrik" uniqKey="Gronberg H" first="Henrik" last="Grönberg">Henrik Grönberg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Gyllensten, Ulf" sort="Gyllensten, Ulf" uniqKey="Gyllensten U" first="Ulf" last="Gyllensten">Ulf Gyllensten</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation wicri:level="1"><nlm:affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="2"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Heliovaara, Markku" sort="Heliovaara, Markku" uniqKey="Heliovaara M" first="Markku" last="Heliövaara">Markku Heliövaara</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Health, National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Hengstenberg, Christian" sort="Hengstenberg, Christian" uniqKey="Hengstenberg C" first="Christian" last="Hengstenberg">Christian Hengstenberg</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München</wicri:regionArea></affiliation></author><author><name sortKey="Hicks, Andrew A" sort="Hicks, Andrew A" uniqKey="Hicks A" first="Andrew A" last="Hicks">Andrew A. Hicks</name><affiliation wicri:level="1"><nlm:affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Hingorani, Aroon" sort="Hingorani, Aroon" uniqKey="Hingorani A" first="Aroon" last="Hingorani">Aroon Hingorani</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiovascular Science, University College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cardiovascular Science, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hu, Frank" sort="Hu, Frank" uniqKey="Hu F" first="Frank" last="Hu">Frank Hu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Huikuri, Heikki V" sort="Huikuri, Heikki V" uniqKey="Huikuri H" first="Heikki V" last="Huikuri">Heikki V. Huikuri</name><affiliation wicri:level="1"><nlm:affiliation>Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim</wicri:regionArea></affiliation></author><author><name sortKey="James, Alan L" sort="James, Alan L" uniqKey="James A" first="Alan L" last="James">Alan L. James</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Jordan, Joanne M" sort="Jordan, Joanne M" uniqKey="Jordan J" first="Joanne M" last="Jordan">Joanne M. Jordan</name><affiliation wicri:level="1"><nlm:affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere</wicri:regionArea></affiliation></author><author><name sortKey="Kajantie, Eero" sort="Kajantie, Eero" uniqKey="Kajantie E" first="Eero" last="Kajantie">Eero Kajantie</name><affiliation wicri:level="1"><nlm:affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Kiemeney, Lambertus A L M" sort="Kiemeney, Lambertus A L M" uniqKey="Kiemeney L" first="Lambertus A L M" last="Kiemeney">Lambertus A L M. Kiemeney</name><affiliation wicri:level="1"><nlm:affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Radboud university medical center, Radboud Institute for Health Sciences, Department of Urology, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Radboud university medical center, Radboud Institute for Health Sciences, Department of Urology, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, UCL, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, UCL, London</wicri:regionArea></affiliation></author><author><name sortKey="Knekt, Paul B" sort="Knekt, Paul B" uniqKey="Knekt P" first="Paul B" last="Knekt">Paul B. Knekt</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Koistinen, Heikki A" sort="Koistinen, Heikki A" uniqKey="Koistinen H" first="Heikki A" last="Koistinen">Heikki A. Koistinen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, Helsinki, Finland; University of Helsinki and Helsinki University Central Hospital, Department of Medicine and Abdominal Center: Endocrinology, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki, Finland; University of Helsinki and Helsinki University Central Hospital, Department of Medicine and Abdominal Center: Endocrinology, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><affiliation wicri:level="1"><nlm:affiliation>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Koskinen, Seppo" sort="Koskinen, Seppo" uniqKey="Koskinen S" first="Seppo" last="Koskinen">Seppo Koskinen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Health, National Institute for Health and Welfare, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Maerz, Winfried" sort="Maerz, Winfried" uniqKey="Maerz W" first="Winfried" last="Maerz">Winfried Maerz</name><affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation wicri:level="1"><nlm:affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Bergofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Lakka, Timo A" sort="Lakka, Timo A" uniqKey="Lakka T" first="Timo A" last="Lakka">Timo A. Lakka</name><affiliation wicri:level="1"><nlm:affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere</wicri:regionArea></affiliation></author><author><name sortKey="Lettre, Guillaume" sort="Lettre, Guillaume" uniqKey="Lettre G" first="Guillaume" last="Lettre">Guillaume Lettre</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Levinson, Douglas F" sort="Levinson, Douglas F" uniqKey="Levinson D" first="Douglas F" last="Levinson">Douglas F. Levinson</name><affiliation wicri:level="1"><nlm:affiliation>Stanford University, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanford University, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea></affiliation></author><author><name sortKey="Lokki, Marja Liisa" sort="Lokki, Marja Liisa" uniqKey="Lokki M" first="Marja-Liisa" last="Lokki">Marja-Liisa Lokki</name><affiliation wicri:level="1"><nlm:affiliation>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="M Ntyselk, Pekka" sort="M Ntyselk, Pekka" uniqKey="M Ntyselk P" first="Pekka" last="M Ntyselk">Pekka M Ntyselk</name><affiliation wicri:level="1"><nlm:affiliation>Primary Health Care Unit, Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Primary Health Care Unit, Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland; Primary Health Care Unit, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Mitchell, Braxton D" sort="Mitchell, Braxton D" uniqKey="Mitchell B" first="Braxton D" last="Mitchell">Braxton D. Mitchell</name><affiliation wicri:level="1"><nlm:affiliation>University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Moll, Frans L" sort="Moll, Frans L" uniqKey="Moll F" first="Frans L" last="Moll">Frans L. Moll</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Utrecht, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Murray, Jeffrey C" sort="Murray, Jeffrey C" uniqKey="Murray J" first="Jeffrey C" last="Murray">Jeffrey C. Murray</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pediatrics, University of Iowa, Iowa City, Iowa</wicri:regionArea></affiliation></author><author><name sortKey="Musk, Arthur W" sort="Musk, Arthur W" uniqKey="Musk A" first="Arthur W" last="Musk">Arthur W. Musk</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea></affiliation></author><author><name sortKey="Nieminen, Markku S" sort="Nieminen, Markku S" uniqKey="Nieminen M" first="Markku S" last="Nieminen">Markku S. Nieminen</name><affiliation wicri:level="1"><nlm:affiliation>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Nj Lstad, Inger" sort="Nj Lstad, Inger" uniqKey="Nj Lstad I" first="Inger" last="Nj Lstad">Inger Nj Lstad</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø</wicri:regionArea></affiliation></author><author><name sortKey="Ohlsson, Claes" sort="Ohlsson, Claes" uniqKey="Ohlsson C" first="Claes" last="Ohlsson">Claes Ohlsson</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea></affiliation></author><author><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J" last="Oldehinkel">Albertine J. Oldehinkel</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center, Interdisciplinary Center Psychopathology and Emotion Regulation, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center, Interdisciplinary Center Psychopathology and Emotion Regulation, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health, University of Adelaide, Adelaide, South Australia, Australia; Robinson Research Institute, University of Adelaide, Adelaide, South Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>School of Public Health, University of Adelaide, Adelaide, South Australia, Australia; Robinson Research Institute, University of Adelaide, Adelaide, South Australia</wicri:regionArea></affiliation></author><author><name sortKey="Pankow, James S" sort="Pankow, James S" uniqKey="Pankow J" first="James S" last="Pankow">James S. Pankow</name><affiliation wicri:level="1"><nlm:affiliation>Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Pasterkamp, Gerard" sort="Pasterkamp, Gerard" uniqKey="Pasterkamp G" first="Gerard" last="Pasterkamp">Gerard Pasterkamp</name><affiliation wicri:level="1"><nlm:affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L" last="Pedersen">Nancy L. Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Pedersen, Oluf" sort="Pedersen, Oluf" uniqKey="Pedersen O" first="Oluf" last="Pedersen">Oluf Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland; Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Pramstaller, Peter P" sort="Pramstaller, Peter P" uniqKey="Pramstaller P" first="Peter P" last="Pramstaller">Peter P. Pramstaller</name><affiliation wicri:level="1"><nlm:affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany; Department of Neurology, General Central Hospital, Bolzano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany; Department of Neurology, General Central Hospital, Bolzano</wicri:regionArea></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="1"><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seatte, Washington, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seatte, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Qi, Lu" sort="Qi, Lu" uniqKey="Qi L" first="Lu" last="Qi">Lu Qi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Quertermous, Thomas" sort="Quertermous, Thomas" uniqKey="Quertermous T" first="Thomas" last="Quertermous">Thomas Quertermous</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Stanford University School of Medicine, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T" last="Raitakari">Olli T. Raitakari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Rankinen, Tuomo" sort="Rankinen, Tuomo" uniqKey="Rankinen T" first="Tuomo" last="Rankinen">Tuomo Rankinen</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana</wicri:regionArea></affiliation></author><author><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name><affiliation wicri:level="1"><nlm:affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><affiliation wicri:level="1"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Rioux, John D" sort="Rioux, John D" uniqKey="Rioux J" first="John D" last="Rioux">John D. Rioux</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="1"><nlm:affiliation>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Den Ruijter, Hester M" sort="Den Ruijter, Hester M" uniqKey="Den Ruijter H" first="Hester M" last="Den Ruijter">Hester M. Den Ruijter</name><affiliation wicri:level="1"><nlm:affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Saltevo, Juha" sort="Saltevo, Juha" uniqKey="Saltevo J" first="Juha" last="Saltevo">Juha Saltevo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, Central Finland Central Hospital, Jyväskylä</wicri:regionArea></affiliation></author><author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name><affiliation wicri:level="1"><nlm:affiliation>BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow</wicri:regionArea></affiliation></author><author><name sortKey="Schunkert, Heribert" sort="Schunkert, Heribert" uniqKey="Schunkert H" first="Heribert" last="Schunkert">Heribert Schunkert</name><affiliation wicri:level="1"><nlm:affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München</wicri:regionArea></affiliation></author><author><name sortKey="Schwarz, Peter E H" sort="Schwarz, Peter E H" uniqKey="Schwarz P" first="Peter E H" last="Schwarz">Peter E H. Schwarz</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Sinisalo, Juha" sort="Sinisalo, Juha" uniqKey="Sinisalo J" first="Juha" last="Sinisalo">Juha Sinisalo</name><affiliation wicri:level="1"><nlm:affiliation>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation wicri:level="1"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="S Rensen, Thorkild I A" sort="S Rensen, Thorkild I A" uniqKey="S Rensen T" first="Thorkild I A" last="S Rensen">Thorkild I A. S Rensen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg</wicri:regionArea></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Staessen, Jan A" sort="Staessen, Jan A" uniqKey="Staessen J" first="Jan A" last="Staessen">Jan A. Staessen</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; R & D VitaK Group, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; R & D VitaK Group, Maastricht University, Maastricht</wicri:regionArea></affiliation></author><author><name sortKey="Stefania, Bandinelli" sort="Stefania, Bandinelli" uniqKey="Stefania B" first="Bandinelli" last="Stefania">Bandinelli Stefania</name><affiliation wicri:level="1"><nlm:affiliation>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence</wicri:regionArea></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation wicri:level="1"><nlm:affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><affiliation wicri:level="1"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Tardif, Jean Claude" sort="Tardif, Jean Claude" uniqKey="Tardif J" first="Jean-Claude" last="Tardif">Jean-Claude Tardif</name><affiliation wicri:level="1"><nlm:affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec</wicri:regionArea></affiliation></author><author><name sortKey="Tremoli, Elena" sort="Tremoli, Elena" uniqKey="Tremoli E" first="Elena" last="Tremoli">Elena Tremoli</name><affiliation wicri:level="1"><nlm:affiliation>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><affiliation wicri:level="1"><nlm:affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria; Instituto de Investigacion Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Spain; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria; Instituto de Investigacion Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Spain; Diabetes Research Group, King Abdulaziz University, Jeddah</wicri:regionArea></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Uusitupa, Matti" sort="Uusitupa, Matti" uniqKey="Uusitupa M" first="Matti" last="Uusitupa">Matti Uusitupa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Research Unit, Kuopio University Hospital, Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Research Unit, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Verbeek, Andre L M" sort="Verbeek, Andre L M" uniqKey="Verbeek A" first="André L M" last="Verbeek">André L M. Verbeek</name><affiliation wicri:level="1"><nlm:affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Vermeulen, Sita H" sort="Vermeulen, Sita H" uniqKey="Vermeulen S" first="Sita H" last="Vermeulen">Sita H. Vermeulen</name><affiliation wicri:level="1"><nlm:affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Department of Human Genetics, Radboud university medical center, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Department of Human Genetics, Radboud university medical center, Nijmegen</wicri:regionArea></affiliation></author><author><name sortKey="Viikari, Jorma S" sort="Viikari, Jorma S" uniqKey="Viikari J" first="Jorma S" last="Viikari">Jorma S. Viikari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation wicri:level="2"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gérard" last="Waeber">Gérard Waeber</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Walker, Mark" sort="Walker, Mark" uniqKey="Walker M" first="Mark" last="Walker">Mark Walker</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Institute of Cellular Medicine, Newcastle University, Newcastle</wicri:regionArea></affiliation></author><author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald</wicri:regionArea></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Zeggini, Eleftheria" sort="Zeggini, Eleftheria" uniqKey="Zeggini E" first="Eleftheria" last="Zeggini">Eleftheria Zeggini</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Chakravarti, Aravinda" sort="Chakravarti, Aravinda" uniqKey="Chakravarti A" first="Aravinda" last="Chakravarti">Aravinda Chakravarti</name><affiliation wicri:level="1"><nlm:affiliation>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Clegg, Deborah J" sort="Clegg, Deborah J" uniqKey="Clegg D" first="Deborah J" last="Clegg">Deborah J. Clegg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Cupples, L Adrienne" sort="Cupples, L Adrienne" uniqKey="Cupples L" first="L Adrienne" last="Cupples">L Adrienne Cupples</name><affiliation wicri:level="1"><nlm:affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Gordon Larsen, Penny" sort="Gordon Larsen, Penny" uniqKey="Gordon Larsen P" first="Penny" last="Gordon-Larsen">Penny Gordon-Larsen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Jaquish, Cashell E" sort="Jaquish, Cashell E" uniqKey="Jaquish C" first="Cashell E" last="Jaquish">Cashell E. Jaquish</name><affiliation wicri:level="1"><nlm:affiliation>National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Rao, D C" sort="Rao, D C" uniqKey="Rao D" first="D C" last="Rao">D C Rao</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Goncalo R" last="Abecasis">Goncalo R. Abecasis</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Assimes, Themistocles L" sort="Assimes, Themistocles L" uniqKey="Assimes T" first="Themistocles L" last="Assimes">Themistocles L. Assimes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Stanford University School of Medicine, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I" last="Berndt">Sonja I. Berndt</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah</wicri:regionArea></affiliation></author><author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S" last="Fox">Caroline S. Fox</name><affiliation wicri:level="1"><nlm:affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Groop, Leif C" sort="Groop, Leif C" uniqKey="Groop L" first="Leif C" last="Groop">Leif C. Groop</name><affiliation wicri:level="1"><nlm:affiliation>Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation wicri:level="1"><nlm:affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California</wicri:regionArea></affiliation></author><author><name sortKey="Kaplan, Robert C" sort="Kaplan, Robert C" uniqKey="Kaplan R" first="Robert C" last="Kaplan">Robert C. Kaplan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York</wicri:regionArea></affiliation></author><author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L" last="Mohlke">Karen L. Mohlke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R" last="O'Connell">Jeffrey R. O'Connell</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Schlessinger, David" sort="Schlessinger, David" uniqKey="Schlessinger D" first="David" last="Schlessinger">David Schlessinger</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, St George's, University of London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Population Health Research Institute, St George's, University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation wicri:level="1"><nlm:affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Center for Medical Systems Biology, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Center for Medical Systems Biology, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N" last="Hirschhorn">Joel N. Hirschhorn</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M" last="Lindgren">Cecilia M. Lindgren</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M" last="Heid">Iris M. Heid</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name><affiliation wicri:level="1"><nlm:affiliation>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea></affiliation></author><author><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B" last="Borecki">Ingrid B. Borecki</name><affiliation wicri:level="1"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltán" last="Kutalik">Zoltán Kutalik</name><affiliation wicri:level="1"><nlm:affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York</wicri:regionArea></affiliation></author></analytic><series><title level="j">PLoS genetics</title><idno type="eISSN">1553-7404</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Body Mass Index</term><term>Body Size (genetics)</term><term>Chromosome Mapping</term><term>European Continental Ancestry Group</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Polymorphism, Single Nucleotide</term><term>Sex Characteristics</term><term>Waist-Hip Ratio</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Caractères sexuels</term><term>Cartographie chromosomique</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Humains</term><term>Indice de masse corporelle</term><term>Mensurations corporelles (génétique)</term><term>Mâle</term><term>Polymorphisme de nucléotide simple</term><term>Population d'origine européenne</term><term>Prédisposition génétique à une maladie</term><term>Rapport taille-hanches</term><term>Sujet âgé</term><term>Étude d'association pangénomique</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Body Size</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Mensurations corporelles</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Body Mass Index</term><term>Chromosome Mapping</term><term>European Continental Ancestry Group</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Polymorphism, Single Nucleotide</term><term>Sex Characteristics</term><term>Waist-Hip Ratio</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Caractères sexuels</term><term>Cartographie chromosomique</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Humains</term><term>Indice de masse corporelle</term><term>Mâle</term><term>Polymorphisme de nucléotide simple</term><term>Population d'origine européenne</term><term>Prédisposition génétique à une maladie</term><term>Rapport taille-hanches</term><term>Sujet âgé</term><term>Étude d'association pangénomique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age- and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to ~2.8M SNPs with BMI and WHRadjBMI in four strata (men ≤50y, men >50y, women ≤50y, women >50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR<5%) age-specific effects, of which 11 had larger effects in younger (<50y) than in older adults (≥50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may provide further insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26426971</PMID><DateCreated><Year>2015</Year><Month>10</Month><Day>02</Day></DateCreated><DateCompleted><Year>2016</Year><Month>05</Month><Day>03</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1553-7404</ISSN><JournalIssue CitedMedium="Internet"><Volume>11</Volume><Issue>10</Issue><PubDate><Year>2015</Year><Month>Oct</Month></PubDate></JournalIssue><Title>PLoS genetics</Title><ISOAbbreviation>PLoS Genet.</ISOAbbreviation></Journal><ArticleTitle>The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.</ArticleTitle><Pagination><MedlinePgn>e1005378</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pgen.1005378</ELocationID><Abstract><AbstractText>Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age- and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to ~2.8M SNPs with BMI and WHRadjBMI in four strata (men ≤50y, men >50y, women ≤50y, women >50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR<5%) age-specific effects, of which 11 had larger effects in younger (<50y) than in older adults (≥50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may provide further insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Winkler</LastName><ForeName>Thomas W</ForeName><Initials>TW</Initials><AffiliationInfo><Affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Justice</LastName><ForeName>Anne E</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Graff</LastName><ForeName>Mariaelisa</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barata</LastName><ForeName>Llilda</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Feitosa</LastName><ForeName>Mary F</ForeName><Initials>MF</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chu</LastName><ForeName>Su</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Czajkowski</LastName><ForeName>Jacek</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Esko</LastName><ForeName>Tõnu</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fall</LastName><ForeName>Tove</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kilpeläinen</LastName><ForeName>Tuomas O</ForeName><Initials>TO</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Yingchang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mägi</LastName><ForeName>Reedik</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mihailov</LastName><ForeName>Evelin</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pers</LastName><ForeName>Tune H</ForeName><Initials>TH</Initials><AffiliationInfo><Affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rüeger</LastName><ForeName>Sina</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Teumer</LastName><ForeName>Alexander</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ehret</LastName><ForeName>Georg B</ForeName><Initials>GB</Initials><AffiliationInfo><Affiliation>Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva, Switzerland; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferreira</LastName><ForeName>Teresa</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heard-Costa</LastName><ForeName>Nancy L</ForeName><Initials>NL</Initials><AffiliationInfo><Affiliation>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karjalainen</LastName><ForeName>Juha</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lagou</LastName><ForeName>Vasiliki</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mahajan</LastName><ForeName>Anubha</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Neinast</LastName><ForeName>Michael D</ForeName><Initials>MD</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prokopenko</LastName><ForeName>Inga</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Hammersmith Hospital, London, United Kingdom; Department of Genomics of Common Diseases, School of Public Health, Imperial College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Simino</LastName><ForeName>Jeannette</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Teslovich</LastName><ForeName>Tanya M</ForeName><Initials>TM</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jansen</LastName><ForeName>Rick</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Westra</LastName><ForeName>Harm-Jan</ForeName><Initials>HJ</Initials><AffiliationInfo><Affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>White</LastName><ForeName>Charles C</ForeName><Initials>CC</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Absher</LastName><ForeName>Devin</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ahluwalia</LastName><ForeName>Tarunveer S</ForeName><Initials>TS</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center A/S, Gentofte, Denmark; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ahmad</LastName><ForeName>Shafqat</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Albrecht</LastName><ForeName>Eva</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alves</LastName><ForeName>Alexessander Couto</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bragg-Gresham</LastName><ForeName>Jennifer L</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Craen</LastName><ForeName>Anton J M</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bis</LastName><ForeName>Joshua C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bonnefond</LastName><ForeName>Amélie</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boucher</LastName><ForeName>Gabrielle</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Montreal Heart Institute, Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cadby</LastName><ForeName>Gemma</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Western Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cheng</LastName><ForeName>Yu-Ching</ForeName><Initials>YC</Initials><AffiliationInfo><Affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chiang</LastName><ForeName>Charleston W K</ForeName><Initials>CW</Initials><AffiliationInfo><Affiliation>Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Delgado</LastName><ForeName>Graciela</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Demirkan</LastName><ForeName>Ayse</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dueker</LastName><ForeName>Nicole</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Universiy of Maryland School of Medicine, Department of Epidemiology & Public Health, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eklund</LastName><ForeName>Niina</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eiriksdottir</LastName><ForeName>Gudny</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Kopavogur, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eriksson</LastName><ForeName>Joel</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Feenstra</LastName><ForeName>Bjarke</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fischer</LastName><ForeName>Krista</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Frau</LastName><ForeName>Francesca</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Galesloot</LastName><ForeName>Tessel E</ForeName><Initials>TE</Initials><AffiliationInfo><Affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Geller</LastName><ForeName>Frank</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goel</LastName><ForeName>Anuj</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gorski</LastName><ForeName>Mathias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grammer</LastName><ForeName>Tanja B</ForeName><Initials>TB</Initials><AffiliationInfo><Affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gustafsson</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haitjema</LastName><ForeName>Saskia</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hottenga</LastName><ForeName>Jouke-Jan</ForeName><Initials>JJ</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huffman</LastName><ForeName>Jennifer E</ForeName><Initials>JE</Initials><AffiliationInfo><Affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jackson</LastName><ForeName>Anne U</ForeName><Initials>AU</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacobs</LastName><ForeName>Kevin B</ForeName><Initials>KB</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johansson</LastName><ForeName>Åsa</ForeName><Initials>Å</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaakinen</LastName><ForeName>Marika</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kleber</LastName><ForeName>Marcus E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lahti</LastName><ForeName>Jari</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Folkhälsan Research Centre, Helsinki, Finland; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mateo Leach</LastName><ForeName>Irene</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lehne</LastName><ForeName>Benjamin</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Youfang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lo</LastName><ForeName>Ken Sin</ForeName><Initials>KS</Initials><AffiliationInfo><Affiliation>Montreal Heart Institute, Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lorentzon</LastName><ForeName>Mattias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luan</LastName><ForeName>Jian'an</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Madden</LastName><ForeName>Pamela A F</ForeName><Initials>PA</Initials><AffiliationInfo><Affiliation>Washington University Medical School, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mangino</LastName><ForeName>Massimo</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McKnight</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Medina-Gomez</LastName><ForeName>Carolina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Monda</LastName><ForeName>Keri L</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; The Center for Observational Research, Amgen Inc., Thousand Oaks, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Montasser</LastName><ForeName>May E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Müller</LastName><ForeName>Gabriele</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Center for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Müller-Nurasyid</LastName><ForeName>Martina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nolte</LastName><ForeName>Ilja M</ForeName><Initials>IM</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Panoutsopoulou</LastName><ForeName>Kalliope</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pascoe</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Institute of Cell & Molecular Biosciences, Newcastle University, Newcastle, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Paternoster</LastName><ForeName>Lavinia</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rayner</LastName><ForeName>Nigel W</ForeName><Initials>NW</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Renström</LastName><ForeName>Frida</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rizzi</LastName><ForeName>Federica</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rose</LastName><ForeName>Lynda M</ForeName><Initials>LM</Initials><AffiliationInfo><Affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ryan</LastName><ForeName>Kathy A</ForeName><Initials>KA</Initials><AffiliationInfo><Affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Salo</LastName><ForeName>Perttu</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanna</LastName><ForeName>Serena</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scharnagl</LastName><ForeName>Hubert</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shi</LastName><ForeName>Jianxin</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>National Cancer Institute, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>Albert Vernon</ForeName><Initials>AV</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Southam</LastName><ForeName>Lorraine</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stančáková</LastName><ForeName>Alena</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steinthorsdottir</LastName><ForeName>Valgerdur</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Strawbridge</LastName><ForeName>Rona J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sung</LastName><ForeName>Yun Ju</ForeName><Initials>YJ</Initials><AffiliationInfo><Affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tachmazidou</LastName><ForeName>Ioanna</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tanaka</LastName><ForeName>Toshiko</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thorleifsson</LastName><ForeName>Gudmar</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Trompet</LastName><ForeName>Stella</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pervjakova</LastName><ForeName>Natalia</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute of Cell and Molecular Biology, Department of Biotechnology, University of Tartu, Tartu, Estonia; University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tyrer</LastName><ForeName>Jonathan P</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Department of Oncology, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vandenput</LastName><ForeName>Liesbeth</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Laan</LastName><ForeName>Sander W</ForeName><Initials>SW</Initials><AffiliationInfo><Affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Velde</LastName><ForeName>Nathalie</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Setten</LastName><ForeName>Jessica</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Vliet-Ostaptchouk</LastName><ForeName>Jana V</ForeName><Initials>JV</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Endocrinology, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Verweij</LastName><ForeName>Niek</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vlachopoulou</LastName><ForeName>Efthymia</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Waite</LastName><ForeName>Lindsay L</ForeName><Initials>LL</Initials><AffiliationInfo><Affiliation>HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Sophie R</ForeName><Initials>SR</Initials><AffiliationInfo><Affiliation>Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, United States of America; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Zhaoming</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wild</LastName><ForeName>Sarah H</ForeName><Initials>SH</Initials><AffiliationInfo><Affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Willenborg</LastName><ForeName>Christina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wilson</LastName><ForeName>James F</ForeName><Initials>JF</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wong</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Jian</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yengo</LastName><ForeName>Loïc</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yerges-Armstrong</LastName><ForeName>Laura M</ForeName><Initials>LM</Initials><AffiliationInfo><Affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yu</LastName><ForeName>Lei</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Weihua</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Jing Hua</ForeName><Initials>JH</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Andersson</LastName><ForeName>Ehm A</ForeName><Initials>EA</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bakker</LastName><ForeName>Stephan J L</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baldassarre</LastName><ForeName>Damiano</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Banasik</LastName><ForeName>Karina</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barcella</LastName><ForeName>Matteo</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Health Sciences, University of Milan, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barlassina</LastName><ForeName>Cristina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Health Sciences, University of Milan, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bellis</LastName><ForeName>Claire</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benaglio</LastName><ForeName>Paola</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blangero</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blüher</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bonnet</LastName><ForeName>Fabrice</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>University Rennes 1, Rennes, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bonnycastle</LastName><ForeName>Lori L</ForeName><Initials>LL</Initials><AffiliationInfo><Affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boyd</LastName><ForeName>Heather A</ForeName><Initials>HA</Initials><AffiliationInfo><Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bruinenberg</LastName><ForeName>Marcel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, The LifeLines Cohort Study, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buchman</LastName><ForeName>Aron S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Campbell</LastName><ForeName>Harry</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Yii-Der Ida</ForeName><Initials>YD</Initials><AffiliationInfo><Affiliation>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chines</LastName><ForeName>Peter S</ForeName><Initials>PS</Initials><AffiliationInfo><Affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Claudi-Boehm</LastName><ForeName>Simone</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cole</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Collins</LastName><ForeName>Francis S</ForeName><Initials>FS</Initials><AffiliationInfo><Affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Geus</LastName><ForeName>Eco J C</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Groot</LastName><ForeName>Lisette C P G M</ForeName><Initials>LC</Initials><AffiliationInfo><Affiliation>Department of Human Nutrition, Wageningen University, Wageningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dimitriou</LastName><ForeName>Maria</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Duan</LastName><ForeName>Jubao</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Enroth</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eury</LastName><ForeName>Elodie</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Farmaki</LastName><ForeName>Aliki-Eleni</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Forouhi</LastName><ForeName>Nita G</ForeName><Initials>NG</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Friedrich</LastName><ForeName>Nele</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gejman</LastName><ForeName>Pablo V</ForeName><Initials>PV</Initials><AffiliationInfo><Affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gigante</LastName><ForeName>Bruna</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Glorioso</LastName><ForeName>Nicola</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Hypertension and Related Disease Centre, AOU-University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Go</LastName><ForeName>Alan S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Kaiser Permanente, Division of Research, Oakland, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gottesman</LastName><ForeName>Omri</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gräßler</LastName><ForeName>Jürgen</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medicine III, Pathobiochemistry, University of Dresden, Dresden, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grallert</LastName><ForeName>Harald</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grarup</LastName><ForeName>Niels</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gu</LastName><ForeName>Yu-Mei</ForeName><Initials>YM</Initials><AffiliationInfo><Affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Broer</LastName><ForeName>Linda</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ham</LastName><ForeName>Annelies C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hansen</LastName><ForeName>Torben</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harris</LastName><ForeName>Tamara B</ForeName><Initials>TB</Initials><AffiliationInfo><Affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, United States of America; National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hartman</LastName><ForeName>Catharina A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hassinen</LastName><ForeName>Maija</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hastie</LastName><ForeName>Nicholas</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hattersley</LastName><ForeName>Andrew T</ForeName><Initials>AT</Initials><AffiliationInfo><Affiliation>Institue of Biomedical & Clinical Science, University of Exeter, Exeter, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heath</LastName><ForeName>Andrew C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Washington University Medical School, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Henders</LastName><ForeName>Anjali K</ForeName><Initials>AK</Initials><AffiliationInfo><Affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hernandez</LastName><ForeName>Dena</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hillege</LastName><ForeName>Hans</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Holmen</LastName><ForeName>Oddgeir</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hovingh</LastName><ForeName>Kees G</ForeName><Initials>KG</Initials><AffiliationInfo><Affiliation>Department Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hui</LastName><ForeName>Jennie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia; School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Husemoen</LastName><ForeName>Lise L</ForeName><Initials>LL</Initials><AffiliationInfo><Affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hutri-Kähönen</LastName><ForeName>Nina</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University of Tampere School of Medicine, Tampere, Finland; Department of Pediatrics,Tampere University Hospital, Tampere, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hysi</LastName><ForeName>Pirro G</ForeName><Initials>PG</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Illig</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany; Institute of Human Genetics, Hannover Medical School, Hanover, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Jager</LastName><ForeName>Philip L</ForeName><Initials>PL</Initials><AffiliationInfo><Affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts,United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jalilzadeh</LastName><ForeName>Shapour</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jørgensen</LastName><ForeName>Torben</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, University of Aalborg, Aalborg, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jukema</LastName><ForeName>J Wouter</ForeName><Initials>JW</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Juonala</LastName><ForeName>Markus</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Medicine, Turku University Hospital, Turku, Finland; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Medicine, University of Turku, Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kanoni</LastName><ForeName>Stavroula</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karaleftheri</LastName><ForeName>Maria</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Echinos Medical Centre, Echinos, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khaw</LastName><ForeName>Kay Tee</ForeName><Initials>KT</Initials><AffiliationInfo><Affiliation>Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kinnunen</LastName><ForeName>Leena</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kittner</LastName><ForeName>Steven J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koenig</LastName><ForeName>Wolfgang</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kolcic</LastName><ForeName>Ivana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kovacs</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Krarup</LastName><ForeName>Nikolaj T</ForeName><Initials>NT</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kratzer</LastName><ForeName>Wolfgang</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Krüger</LastName><ForeName>Janine</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kuh</LastName><ForeName>Diana</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kumari</LastName><ForeName>Meena</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Public Health, UCL, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kyriakou</LastName><ForeName>Theodosios</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Langenberg</LastName><ForeName>Claudia</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Public Health, UCL, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lannfelt</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lanzani</LastName><ForeName>Chiara</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Chair of Nephrology, Università Vita Salute San Raffaele, Segrate (Milan), Italy; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Segrate (Milan), Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lotay</LastName><ForeName>Vaneet</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Launer</LastName><ForeName>Lenore J</ForeName><Initials>LJ</Initials><AffiliationInfo><Affiliation>National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leander</LastName><ForeName>Karin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lindström</LastName><ForeName>Jaana</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Linneberg</LastName><ForeName>Allan</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Yan-Ping</ForeName><Initials>YP</Initials><AffiliationInfo><Affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lobbens</LastName><ForeName>Stéphane</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luben</LastName><ForeName>Robert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Strangeways Research Laboratory Wort's Causeway, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lyssenko</LastName><ForeName>Valeriya</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Steno Diabetes Center A/S, Gentofte, Denmark; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Männistö</LastName><ForeName>Satu</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Magnusson</LastName><ForeName>Patrik K</ForeName><Initials>PK</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McArdle</LastName><ForeName>Wendy L</ForeName><Initials>WL</Initials><AffiliationInfo><Affiliation>School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Menni</LastName><ForeName>Cristina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Merger</LastName><ForeName>Sigrun</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Milani</LastName><ForeName>Lili</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Montgomery</LastName><ForeName>Grant W</ForeName><Initials>GW</Initials><AffiliationInfo><Affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Morris</LastName><ForeName>Andrew P</ForeName><Initials>AP</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Narisu</LastName><ForeName>Narisu</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nelis</LastName><ForeName>Mari</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ong</LastName><ForeName>Ken K</ForeName><Initials>KK</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Palotie</LastName><ForeName>Aarno</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pérusse</LastName><ForeName>Louis</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Kinesiology, Laval University, Québec City, Québec, Canada; Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pichler</LastName><ForeName>Irene</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pilia</LastName><ForeName>Maria G</ForeName><Initials>MG</Initials><AffiliationInfo><Affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pouta</LastName><ForeName>Anneli</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Children, Young People and Families, National Institute for Health and Welfare, Helsinki, Finland; Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rheinberger</LastName><ForeName>Myriam</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ribel-Madsen</LastName><ForeName>Rasmus</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Richards</LastName><ForeName>Marcus</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rice</LastName><ForeName>Kenneth M</ForeName><Initials>KM</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rice</LastName><ForeName>Treva K</ForeName><Initials>TK</Initials><AffiliationInfo><Affiliation>Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rivolta</LastName><ForeName>Carlo</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Salomaa</LastName><ForeName>Veikko</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanders</LastName><ForeName>Alan R</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sarzynski</LastName><ForeName>Mark A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scholtens</LastName><ForeName>Salome</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scott</LastName><ForeName>Robert A</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scott</LastName><ForeName>William R</ForeName><Initials>WR</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sebert</LastName><ForeName>Sylvain</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institute of Health Sciences, University of Oulu, Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sengupta</LastName><ForeName>Sebanti</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sennblad</LastName><ForeName>Bengt</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Seufferlein</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Silveira</LastName><ForeName>Angela</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Slagboom</LastName><ForeName>P Eline</ForeName><Initials>PE</Initials><AffiliationInfo><Affiliation>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smit</LastName><ForeName>Jan H</ForeName><Initials>JH</Initials><AffiliationInfo><Affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sparsø</LastName><ForeName>Thomas H</ForeName><Initials>TH</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stirrups</LastName><ForeName>Kathleen</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stolk</LastName><ForeName>Ronald P</ForeName><Initials>RP</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stringham</LastName><ForeName>Heather M</ForeName><Initials>HM</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Swertz</LastName><ForeName>Morris A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Swift</LastName><ForeName>Amy J</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Syvänen</LastName><ForeName>Ann-Christine</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tan</LastName><ForeName>Sian-Tsung</ForeName><Initials>ST</Initials><AffiliationInfo><Affiliation>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thorand</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tönjes</LastName><ForeName>Anke</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>University of Leipzig, Department of Medicine, Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tremblay</LastName><ForeName>Angelo</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Kinesiology, Laval University, Québec City, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tsafantakis</LastName><ForeName>Emmanouil</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Anogia Medical Centre, Anogia, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Most</LastName><ForeName>Peter J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Völker</LastName><ForeName>Uwe</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vohl</LastName><ForeName>Marie-Claude</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada; School of Nutrition, Laval University, Québec City, Québec,Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vonk</LastName><ForeName>Judith M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Waldenberger</LastName><ForeName>Melanie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walker</LastName><ForeName>Ryan W</ForeName><Initials>RW</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wennauer</LastName><ForeName>Roman</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Clinical Chemistry, Ulm University Medical Centre, Ulm, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Widén</LastName><ForeName>Elisabeth</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Willemsen</LastName><ForeName>Gonneke</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wilsgaard</LastName><ForeName>Tom</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wright</LastName><ForeName>Alan F</ForeName><Initials>AF</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zillikens</LastName><ForeName>M Carola</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Dijk</LastName><ForeName>Suzanne C</ForeName><Initials>SC</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Schoor</LastName><ForeName>Natasja M</ForeName><Initials>NM</Initials><AffiliationInfo><Affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; VUMC, Department of Epidemiology and Biostatistics, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Asselbergs</LastName><ForeName>Folkert W</ForeName><Initials>FW</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands; Institute of Cardiovascular Science, University College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Bakker</LastName><ForeName>Paul I W</ForeName><Initials>PI</Initials><AffiliationInfo><Affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands; Department of Epidemiology, University Medical Center, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beckmann</LastName><ForeName>Jacques S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beilby</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bennett</LastName><ForeName>David A</ForeName><Initials>DA</Initials><AffiliationInfo><Affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bergman</LastName><ForeName>Richard N</ForeName><Initials>RN</Initials><AffiliationInfo><Affiliation>Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bergmann</LastName><ForeName>Sven</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Böger</LastName><ForeName>Carsten A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boehm</LastName><ForeName>Bernhard O</ForeName><Initials>BO</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany; Imperial College London, London, United Kingdom; Lee Kong Chian School of Medicine, Singapore, Singapore; Nanyang Technological University, Singapore, Singapore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boerwinkle</LastName><ForeName>Eric</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boomsma</LastName><ForeName>Dorret I</ForeName><Initials>DI</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, VU University, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bornstein</LastName><ForeName>Stefan R</ForeName><Initials>SR</Initials><AffiliationInfo><Affiliation>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bottinger</LastName><ForeName>Erwin P</ForeName><Initials>EP</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bouchard</LastName><ForeName>Claude</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chambers</LastName><ForeName>John C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chanock</LastName><ForeName>Stephen J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chasman</LastName><ForeName>Daniel I</ForeName><Initials>DI</Initials><AffiliationInfo><Affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cucca</LastName><ForeName>Francesco</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy; University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cusi</LastName><ForeName>Daniele</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Health Sciences, University of Milan, Milan, Italy; Institute of Biomedical Technologies, National Institute of Research, Segrate-Milano, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dedoussis</LastName><ForeName>George</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Erdmann</LastName><ForeName>Jeanette</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eriksson</LastName><ForeName>Johan G</ForeName><Initials>JG</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Folkhälsan Research Centre, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>Denis A</ForeName><Initials>DA</Initials><AffiliationInfo><Affiliation>Rush Institute for Healthy Aging and Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Faire</LastName><ForeName>Ulf</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Farrall</LastName><ForeName>Martin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferrucci</LastName><ForeName>Luigi</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ford</LastName><ForeName>Ian</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Robertson Center for Biostatistics, University of Glasgow, Glasgow, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Franke</LastName><ForeName>Lude</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Franks</LastName><ForeName>Paul W</ForeName><Initials>PW</Initials><AffiliationInfo><Affiliation>Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden; Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden, Umeå, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Froguel</LastName><ForeName>Philippe</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gansevoort</LastName><ForeName>Ron T</ForeName><Initials>RT</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gieger</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grönberg</LastName><ForeName>Henrik</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gudnason</LastName><ForeName>Vilmundur</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gyllensten</LastName><ForeName>Ulf</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hall</LastName><ForeName>Per</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hamsten</LastName><ForeName>Anders</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Harst</LastName><ForeName>Pim</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hayward</LastName><ForeName>Caroline</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heliövaara</LastName><ForeName>Markku</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hengstenberg</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hicks</LastName><ForeName>Andrew A</ForeName><Initials>AA</Initials><AffiliationInfo><Affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hingorani</LastName><ForeName>Aroon</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Cardiovascular Science, University College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hofman</LastName><ForeName>Albert</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hu</LastName><ForeName>Frank</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huikuri</LastName><ForeName>Heikki V</ForeName><Initials>HV</Initials><AffiliationInfo><Affiliation>Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hveem</LastName><ForeName>Kristian</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>James</LastName><ForeName>Alan L</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jordan</LastName><ForeName>Joanne M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jula</LastName><ForeName>Antti</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kähönen</LastName><ForeName>Mika</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kajantie</LastName><ForeName>Eero</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kathiresan</LastName><ForeName>Sekar</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kiemeney</LastName><ForeName>Lambertus A L M</ForeName><Initials>LA</Initials><AffiliationInfo><Affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Radboud university medical center, Radboud Institute for Health Sciences, Department of Urology, Nijmegen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kivimaki</LastName><ForeName>Mika</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Public Health, UCL, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Knekt</LastName><ForeName>Paul B</ForeName><Initials>PB</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koistinen</LastName><ForeName>Heikki A</ForeName><Initials>HA</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Helsinki, Finland; University of Helsinki and Helsinki University Central Hospital, Department of Medicine and Abdominal Center: Endocrinology, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kooner</LastName><ForeName>Jaspal S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koskinen</LastName><ForeName>Seppo</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Health, National Institute for Health and Welfare, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kuusisto</LastName><ForeName>Johanna</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maerz</LastName><ForeName>Winfried</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martin</LastName><ForeName>Nicholas G</ForeName><Initials>NG</Initials><AffiliationInfo><Affiliation>QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Laakso</LastName><ForeName>Markku</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lakka</LastName><ForeName>Timo A</ForeName><Initials>TA</Initials><AffiliationInfo><Affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lehtimäki</LastName><ForeName>Terho</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lettre</LastName><ForeName>Guillaume</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Levinson</LastName><ForeName>Douglas F</ForeName><Initials>DF</Initials><AffiliationInfo><Affiliation>Stanford University, Stanford, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lind</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lokki</LastName><ForeName>Marja-Liisa</ForeName><Initials>ML</Initials><AffiliationInfo><Affiliation>Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mäntyselkä</LastName><ForeName>Pekka</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Primary Health Care Unit, Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Melbye</LastName><ForeName>Mads</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Metspalu</LastName><ForeName>Andres</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mitchell</LastName><ForeName>Braxton D</ForeName><Initials>BD</Initials><AffiliationInfo><Affiliation>University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moll</LastName><ForeName>Frans L</ForeName><Initials>FL</Initials><AffiliationInfo><Affiliation>Department of Surgery, University Medical Center Utrecht, Utrecht, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Murray</LastName><ForeName>Jeffrey C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Musk</LastName><ForeName>Arthur W</ForeName><Initials>AW</Initials><AffiliationInfo><Affiliation>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nieminen</LastName><ForeName>Markku S</ForeName><Initials>MS</Initials><AffiliationInfo><Affiliation>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Njølstad</LastName><ForeName>Inger</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ohlsson</LastName><ForeName>Claes</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oldehinkel</LastName><ForeName>Albertine J</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center, Interdisciplinary Center Psychopathology and Emotion Regulation, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oostra</LastName><ForeName>Ben A</ForeName><Initials>BA</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Palmer</LastName><ForeName>Lyle J</ForeName><Initials>LJ</Initials><AffiliationInfo><Affiliation>School of Public Health, University of Adelaide, Adelaide, South Australia, Australia; Robinson Research Institute, University of Adelaide, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pankow</LastName><ForeName>James S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pasterkamp</LastName><ForeName>Gerard</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pedersen</LastName><ForeName>Nancy L</ForeName><Initials>NL</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pedersen</LastName><ForeName>Oluf</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Penninx</LastName><ForeName>Brenda W</ForeName><Initials>BW</Initials><AffiliationInfo><Affiliation>Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perola</LastName><ForeName>Markus</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peters</LastName><ForeName>Annette</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Polašek</LastName><ForeName>Ozren</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pramstaller</LastName><ForeName>Peter P</ForeName><Initials>PP</Initials><AffiliationInfo><Affiliation>Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany; Department of Neurology, General Central Hospital, Bolzano, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Psaty</LastName><ForeName>Bruce M</ForeName><Initials>BM</Initials><AffiliationInfo><Affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seatte, Washington, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qi</LastName><ForeName>Lu</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Quertermous</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raitakari</LastName><ForeName>Olli T</ForeName><Initials>OT</Initials><AffiliationInfo><Affiliation>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rankinen</LastName><ForeName>Tuomo</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rauramaa</LastName><ForeName>Rainer</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ridker</LastName><ForeName>Paul M</ForeName><Initials>PM</Initials><AffiliationInfo><Affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rioux</LastName><ForeName>John D</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rivadeneira</LastName><ForeName>Fernando</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rotter</LastName><ForeName>Jerome I</ForeName><Initials>JI</Initials><AffiliationInfo><Affiliation>Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudan</LastName><ForeName>Igor</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>den Ruijter</LastName><ForeName>Hester M</ForeName><Initials>HM</Initials><AffiliationInfo><Affiliation>Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saltevo</LastName><ForeName>Juha</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sattar</LastName><ForeName>Naveed</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schunkert</LastName><ForeName>Heribert</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schwarz</LastName><ForeName>Peter E H</ForeName><Initials>PE</Initials><AffiliationInfo><Affiliation>Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shuldiner</LastName><ForeName>Alan R</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sinisalo</LastName><ForeName>Juha</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Snieder</LastName><ForeName>Harold</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sørensen</LastName><ForeName>Thorkild I A</ForeName><Initials>TI</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spector</LastName><ForeName>Tim D</ForeName><Initials>TD</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Staessen</LastName><ForeName>Jan A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; R & D VitaK Group, Maastricht University, Maastricht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stefania</LastName><ForeName>Bandinelli</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thorsteinsdottir</LastName><ForeName>Unnur</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stumvoll</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tardif</LastName><ForeName>Jean-Claude</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tremoli</LastName><ForeName>Elena</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tuomilehto</LastName><ForeName>Jaakko</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria; Instituto de Investigacion Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Spain; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Uitterlinden</LastName><ForeName>André G</ForeName><Initials>AG</Initials><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Uusitupa</LastName><ForeName>Matti</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Research Unit, Kuopio University Hospital, Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Verbeek</LastName><ForeName>André L M</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vermeulen</LastName><ForeName>Sita H</ForeName><Initials>SH</Initials><AffiliationInfo><Affiliation>Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Department of Human Genetics, Radboud university medical center, Nijmegen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Viikari</LastName><ForeName>Jorma S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Turku, Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vitart</LastName><ForeName>Veronique</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Völzke</LastName><ForeName>Henry</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vollenweider</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Waeber</LastName><ForeName>Gérard</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walker</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wallaschofski</LastName><ForeName>Henri</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wareham</LastName><ForeName>Nicholas J</ForeName><Initials>NJ</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Watkins</LastName><ForeName>Hugh</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zeggini</LastName><ForeName>Eleftheria</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>CHARGE Consortium</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>DIAGRAM Consortium</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>GLGC Consortium</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>Global-BPGen Consortium</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>ICBP Consortium</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>MAGIC Consortium</CollectiveName></Author><Author ValidYN="Y"><LastName>Chakravarti</LastName><ForeName>Aravinda</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Clegg</LastName><ForeName>Deborah J</ForeName><Initials>DJ</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cupples</LastName><ForeName>L Adrienne</ForeName><Initials>LA</Initials><AffiliationInfo><Affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gordon-Larsen</LastName><ForeName>Penny</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jaquish</LastName><ForeName>Cashell E</ForeName><Initials>CE</Initials><AffiliationInfo><Affiliation>National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rao</LastName><ForeName>D C</ForeName><Initials>DC</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abecasis</LastName><ForeName>Goncalo R</ForeName><Initials>GR</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Assimes</LastName><ForeName>Themistocles L</ForeName><Initials>TL</Initials><AffiliationInfo><Affiliation>Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barroso</LastName><ForeName>Inês</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Berndt</LastName><ForeName>Sonja I</ForeName><Initials>SI</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boehnke</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Deloukas</LastName><ForeName>Panos</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>Caroline S</ForeName><Initials>CS</Initials><AffiliationInfo><Affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Groop</LastName><ForeName>Leif C</ForeName><Initials>LC</Initials><AffiliationInfo><Affiliation>Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hunter</LastName><ForeName>David J</ForeName><Initials>DJ</Initials><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ingelsson</LastName><ForeName>Erik</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaplan</LastName><ForeName>Robert C</ForeName><Initials>RC</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McCarthy</LastName><ForeName>Mark I</ForeName><Initials>MI</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mohlke</LastName><ForeName>Karen L</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Connell</LastName><ForeName>Jeffrey R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schlessinger</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Strachan</LastName><ForeName>David P</ForeName><Initials>DP</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, St George's, University of London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stefansson</LastName><ForeName>Kari</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Duijn</LastName><ForeName>Cornelia M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Center for Medical Systems Biology, Leiden, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hirschhorn</LastName><ForeName>Joel N</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lindgren</LastName><ForeName>Cecilia M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heid</LastName><ForeName>Iris M</ForeName><Initials>IM</Initials><AffiliationInfo><Affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>North</LastName><ForeName>Kari E</ForeName><Initials>KE</Initials><AffiliationInfo><Affiliation>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borecki</LastName><ForeName>Ingrid B</ForeName><Initials>IB</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kutalik</LastName><ForeName>Zoltán</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Loos</LastName><ForeName>Ruth J F</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>G1001799</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>098017</GrantID><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>RG/13/2/30098</GrantID><Agency>British Heart Foundation</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>RF1 AG015819</GrantID><Acronym>AG</Acronym><Agency>NIA NIH 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Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 HL105756</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_U106179471</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/N01104X/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 DK063491</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_UU_12015/2</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 AG010161</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P30 DK072488</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>14136</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MC_U106179472</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>G0401527</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 DK020541</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_PC_U127561128</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>UM1 CA182913</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>098395</GrantID><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>U01 DK062370</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 DK089256</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MR/K013351/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 DK020572</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_UU_12015/5</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 AG011101</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P60 DK020541</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>098381</GrantID><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 HL117078</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P2C HD050924</GrantID><Acronym>HD</Acronym><Agency>NICHD NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>T32 HL007055</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>10</Month><Day>01</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>PLoS Genet</MedlineTA><NlmUniqueID>101239074</NlmUniqueID><ISSNLinking>1553-7390</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>PLoS Genet. 2016 Jun;12(6):e1006166</RefSource><PMID Version="1">27355579</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2005 Nov 5;366(9497):1640-9</RefSource><PMID 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MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020022" MajorTopicYN="Y">Genetic Predisposition to Disease</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055106" MajorTopicYN="Y">Genome-Wide Association Study</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020641" MajorTopicYN="N">Polymorphism, Single Nucleotide</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012727" MajorTopicYN="N">Sex Characteristics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D049629" MajorTopicYN="N">Waist-Hip Ratio</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC4591371</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>11</Month><Day>19</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>06</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>10</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>10</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>5</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26426971</ArticleId><ArticleId IdType="doi">10.1371/journal.pgen.1005378</ArticleId><ArticleId IdType="pii">PGENETICS-D-14-03117</ArticleId><ArticleId IdType="pmc">PMC4591371</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler 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