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Menopause as a predictor of new-onset asthma: A longitudinal Northern European population study.

Identifieur interne : 002375 ( PubMed/Curation ); précédent : 002374; suivant : 002376

Menopause as a predictor of new-onset asthma: A longitudinal Northern European population study.

Auteurs : Kai Triebner [Norvège] ; Ane Johannessen [Norvège] ; Luca Puggini [Irlande (pays)] ; Bryndís Benediktsd Ttir [Islande] ; Randi J. Bertelsen [Norvège] ; Ersilia Bifulco [Norvège] ; Shyamali C. Dharmage [Australie] ; Julia Dratva [Suisse] ; Karl A. Franklin [Suède] ; Th Rarinn Gíslason [Islande] ; Mathias Holm [Suède] ; Deborah Jarvis [Royaume-Uni] ; Bénédicte Leynaert [France] ; Eva Lindberg [Suède] ; Andrei Malinovschi [Suède] ; Ferenc Macsali [Norvège] ; Dan Norb Ck [Suède] ; Ernst R. Omenaas [Norvège] ; Francisco J. Rodríguez [Espagne] ; Eirunn Saure [Norvège] ; Vivi Schlünssen [Danemark] ; Torben Sigsgaard [Danemark] ; Trude D. Skorge [Norvège] ; Gunilla Wieslander [Suède] ; Elisabeth Zemp [Suisse] ; Cecilie Svanes [Norvège] ; Steinar Hustad [Norvège] ; Francisco G Mez Real [Norvège]

Source :

RBID : pubmed:26435006

Descripteurs français

English descriptors

Abstract

There is limited and conflicting evidence on the effect of menopause on asthma.

DOI: 10.1016/j.jaci.2015.08.019
PubMed: 26435006

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pubmed:26435006

Le document en format XML

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<name sortKey="Omenaas, Ernst R" sort="Omenaas, Ernst R" uniqKey="Omenaas E" first="Ernst R" last="Omenaas">Ernst R. Omenaas</name>
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<name sortKey="Rodriguez, Francisco J" sort="Rodriguez, Francisco J" uniqKey="Rodriguez F" first="Francisco J" last="Rodríguez">Francisco J. Rodríguez</name>
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<name sortKey="Schlunssen, Vivi" sort="Schlunssen, Vivi" uniqKey="Schlunssen V" first="Vivi" last="Schlünssen">Vivi Schlünssen</name>
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<name sortKey="Svanes, Cecilie" sort="Svanes, Cecilie" uniqKey="Svanes C" first="Cecilie" last="Svanes">Cecilie Svanes</name>
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<name sortKey="G Mez Real, Francisco" sort="G Mez Real, Francisco" uniqKey="G Mez Real F" first="Francisco" last="G Mez Real">Francisco G Mez Real</name>
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<wicri:regionArea>Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen</wicri:regionArea>
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<title xml:lang="en">Menopause as a predictor of new-onset asthma: A longitudinal Northern European population study.</title>
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<nlm:affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway.</nlm:affiliation>
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<nlm:affiliation>Department of Occupational Medicine, University of Bergen, Bergen, Norway.</nlm:affiliation>
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<name sortKey="Dharmage, Shyamali C" sort="Dharmage, Shyamali C" uniqKey="Dharmage S" first="Shyamali C" last="Dharmage">Shyamali C. Dharmage</name>
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<name sortKey="Franklin, Karl A" sort="Franklin, Karl A" uniqKey="Franklin K" first="Karl A" last="Franklin">Karl A. Franklin</name>
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<name sortKey="Gislason, Th Rarinn" sort="Gislason, Th Rarinn" uniqKey="Gislason T" first="Th Rarinn" last="Gíslason">Th Rarinn Gíslason</name>
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<name sortKey="Holm, Mathias" sort="Holm, Mathias" uniqKey="Holm M" first="Mathias" last="Holm">Mathias Holm</name>
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<nlm:affiliation>Department of Occupational and Environmental Medicine, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Occupational and Environmental Medicine, University of Gothenburg, Gothenburg</wicri:regionArea>
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<name sortKey="Jarvis, Deborah" sort="Jarvis, Deborah" uniqKey="Jarvis D" first="Deborah" last="Jarvis">Deborah Jarvis</name>
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<nlm:affiliation>Department of Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College, London</wicri:regionArea>
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<name sortKey="Leynaert, Benedicte" sort="Leynaert, Benedicte" uniqKey="Leynaert B" first="Bénédicte" last="Leynaert">Bénédicte Leynaert</name>
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<nlm:affiliation>Inserm UMR1152 Team of Epidemiology, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
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<name sortKey="Lindberg, Eva" sort="Lindberg, Eva" uniqKey="Lindberg E" first="Eva" last="Lindberg">Eva Lindberg</name>
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<nlm:affiliation>Department of Medical Sciences, Lung Medicine and Allergology, Uppsala University, Uppsala, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Lung Medicine and Allergology, Uppsala University, Uppsala</wicri:regionArea>
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<name sortKey="Malinovschi, Andrei" sort="Malinovschi, Andrei" uniqKey="Malinovschi A" first="Andrei" last="Malinovschi">Andrei Malinovschi</name>
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<nlm:affiliation>Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Macsali, Ferenc" sort="Macsali, Ferenc" uniqKey="Macsali F" first="Ferenc" last="Macsali">Ferenc Macsali</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Norb Ck, Dan" sort="Norb Ck, Dan" uniqKey="Norb Ck D" first="Dan" last="Norb Ck">Dan Norb Ck</name>
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<nlm:affiliation>Department of Medical Sciences, Occupational and Environmental Medicine, University of Uppsala, Uppsala, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Occupational and Environmental Medicine, University of Uppsala, Uppsala</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Omenaas, Ernst R" sort="Omenaas, Ernst R" uniqKey="Omenaas E" first="Ernst R" last="Omenaas">Ernst R. Omenaas</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Clinical Science, University of Bergen, Bergen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Rodriguez, Francisco J" sort="Rodriguez, Francisco J" uniqKey="Rodriguez F" first="Francisco J" last="Rodríguez">Francisco J. Rodríguez</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Applied Mathematics, Málaga University, Málaga, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Applied Mathematics, Málaga University, Málaga</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Saure, Eirunn" sort="Saure, Eirunn" uniqKey="Saure E" first="Eirunn" last="Saure">Eirunn Saure</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Occupational Medicine, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Occupational Medicine, University of Bergen, Bergen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Schlunssen, Vivi" sort="Schlunssen, Vivi" uniqKey="Schlunssen V" first="Vivi" last="Schlünssen">Vivi Schlünssen</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Public Health, Aarhus University, Aarhus, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Public Health, Aarhus University, Aarhus</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Sigsgaard, Torben" sort="Sigsgaard, Torben" uniqKey="Sigsgaard T" first="Torben" last="Sigsgaard">Torben Sigsgaard</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Public Health, Aarhus University, Aarhus, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Public Health, Aarhus University, Aarhus</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Skorge, Trude D" sort="Skorge, Trude D" uniqKey="Skorge T" first="Trude D" last="Skorge">Trude D. Skorge</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Occupational Medicine, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Occupational Medicine, University of Bergen, Bergen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Wieslander, Gunilla" sort="Wieslander, Gunilla" uniqKey="Wieslander G" first="Gunilla" last="Wieslander">Gunilla Wieslander</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Medical Sciences, Occupational and Environmental Medicine, University of Uppsala, Uppsala, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, Occupational and Environmental Medicine, University of Uppsala, Uppsala</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Zemp, Elisabeth" sort="Zemp, Elisabeth" uniqKey="Zemp E" first="Elisabeth" last="Zemp">Elisabeth Zemp</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Public Health and Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Public Health and Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Svanes, Cecilie" sort="Svanes, Cecilie" uniqKey="Svanes C" first="Cecilie" last="Svanes">Cecilie Svanes</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Occupational Medicine, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Occupational Medicine, University of Bergen, Bergen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Hustad, Steinar" sort="Hustad, Steinar" uniqKey="Hustad S" first="Steinar" last="Hustad">Steinar Hustad</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway; Core Facility for Metabolomics, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Clinical Science, University of Bergen, Bergen, Norway; Core Facility for Metabolomics, University of Bergen, Bergen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="G Mez Real, Francisco" sort="G Mez Real, Francisco" uniqKey="G Mez Real F" first="Francisco" last="G Mez Real">Francisco G Mez Real</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series>
<title level="j">The Journal of allergy and clinical immunology</title>
<idno type="eISSN">1097-6825</idno>
<imprint>
<date when="2016" type="published">2016</date>
</imprint>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Aged</term>
<term>Aging (physiology)</term>
<term>Asthma (blood)</term>
<term>Asthma (epidemiology)</term>
<term>Estradiol (blood)</term>
<term>Europe (epidemiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Longitudinal Studies</term>
<term>Menopause (blood)</term>
<term>Middle Aged</term>
<term>Odds Ratio</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte d'âge moyen</term>
<term>Asthme (sang)</term>
<term>Asthme (épidémiologie)</term>
<term>Europe (épidémiologie)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Ménopause (sang)</term>
<term>Odds ratio</term>
<term>Oestradiol (sang)</term>
<term>Sujet âgé</term>
<term>Vieillissement (physiologie)</term>
<term>Études longitudinales</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en">
<term>Estradiol</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en">
<term>Europe</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en">
<term>Asthma</term>
<term>Menopause</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Asthma</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr">
<term>Vieillissement</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en">
<term>Aging</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr">
<term>Asthme</term>
<term>Ménopause</term>
<term>Oestradiol</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Asthme</term>
<term>Europe</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Longitudinal Studies</term>
<term>Middle Aged</term>
<term>Odds Ratio</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Odds ratio</term>
<term>Sujet âgé</term>
<term>Études longitudinales</term>
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<front>
<div type="abstract" xml:lang="en">There is limited and conflicting evidence on the effect of menopause on asthma.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">26435006</PMID>
<DateCreated>
<Year>2016</Year>
<Month>01</Month>
<Day>15</Day>
</DateCreated>
<DateCompleted>
<Year>2016</Year>
<Month>05</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised>
<Year>2017</Year>
<Month>09</Month>
<Day>04</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1097-6825</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>137</Volume>
<Issue>1</Issue>
<PubDate>
<Year>2016</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>The Journal of allergy and clinical immunology</Title>
<ISOAbbreviation>J. Allergy Clin. Immunol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Menopause as a predictor of new-onset asthma: A longitudinal Northern European population study.</ArticleTitle>
<Pagination>
<MedlinePgn>50-57.e6</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S0091-6749(15)01243-9</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jaci.2015.08.019</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">There is limited and conflicting evidence on the effect of menopause on asthma.</AbstractText>
<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">We sought to study whether the incidence of asthma and respiratory symptoms differ by menopausal status in a longitudinal population-based study with an average follow-up of 12 years.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The Respiratory Health in Northern Europe study provided questionnaire data pertaining to respiratory and reproductive health at baseline (1999-2001) and follow-up (2010-2012). The study cohort included women aged 45 to 65 years at follow-up, without asthma at baseline, and not using exogenous hormones (n = 2322). Menopausal status was defined as nonmenopausal, transitional, early postmenopausal, and late postmenopausal. Associations with asthma (defined by the use of asthma medication, having asthma attacks, or both) and respiratory symptoms scores were analyzed by using logistic (asthma) and negative binomial (respiratory symptoms) regressions, adjusting for age, body mass index, physical activity, smoking, education, and study center.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The odds of new-onset asthma were increased in women who were transitional (odds ratio, 2.40; 95% CI, 1.09-5.30), early postmenopausal (odds ratio, 2.11; 95% CI, 1.06-4.20), and late postmenopausal (odds ratio, 3.44; 95% CI, 1.31-9.05) at follow-up compared with nonmenopausal women. The risk of respiratory symptoms increased in early postmenopausal (coefficient, 0.40; 95% CI, 0.06-0.75) and late postmenopausal (coefficient, 0.69; 95% CI, 0.15-1.23) women. These findings were consistent irrespective of smoking status and across study centers.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">New-onset asthma and respiratory symptoms increased in women becoming postmenopausal in a longitudinal population-based study. Clinicians should be aware that respiratory health might deteriorate in women during reproductive aging.</AbstractText>
<CopyrightInformation>Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
</Abstract>
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<Author ValidYN="Y">
<LastName>Triebner</LastName>
<ForeName>Kai</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway. Electronic address: kai.triebner@uib.no.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Johannessen</LastName>
<ForeName>Ane</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Puggini</LastName>
<ForeName>Luca</ForeName>
<Initials>L</Initials>
<AffiliationInfo>
<Affiliation>Department of Electronic Engineering National University of Ireland, Maynooth, Ireland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Benediktsdóttir</LastName>
<ForeName>Bryndís</ForeName>
<Initials>B</Initials>
<AffiliationInfo>
<Affiliation>Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Bertelsen</LastName>
<ForeName>Randi J</ForeName>
<Initials>RJ</Initials>
<AffiliationInfo>
<Affiliation>Department of Occupational Medicine, University of Bergen, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Bifulco</LastName>
<ForeName>Ersilia</ForeName>
<Initials>E</Initials>
<AffiliationInfo>
<Affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway; Core Facility for Metabolomics, University of Bergen, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Dharmage</LastName>
<ForeName>Shyamali C</ForeName>
<Initials>SC</Initials>
<AffiliationInfo>
<Affiliation>Allergy and Lung Health Unit, Melbourne School of Population Health, University of Melbourne, Melbourne, Australia.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Dratva</LastName>
<ForeName>Julia</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Public Health and Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Franklin</LastName>
<ForeName>Karl A</ForeName>
<Initials>KA</Initials>
<AffiliationInfo>
<Affiliation>Department of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Gíslason</LastName>
<ForeName>Thórarinn</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Faculty of Medicine, University of Iceland, Reykjavik, Iceland; Department of Respiratory Medicine and Sleep, Landspitali-the National University Hospital of Iceland, Reykjavik, Iceland.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Holm</LastName>
<ForeName>Mathias</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Occupational and Environmental Medicine, University of Gothenburg, Gothenburg, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Jarvis</LastName>
<ForeName>Deborah</ForeName>
<Initials>D</Initials>
<AffiliationInfo>
<Affiliation>Department of Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Leynaert</LastName>
<ForeName>Bénédicte</ForeName>
<Initials>B</Initials>
<AffiliationInfo>
<Affiliation>Inserm UMR1152 Team of Epidemiology, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Lindberg</LastName>
<ForeName>Eva</ForeName>
<Initials>E</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Sciences, Lung Medicine and Allergology, Uppsala University, Uppsala, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Malinovschi</LastName>
<ForeName>Andrei</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Macsali</LastName>
<ForeName>Ferenc</ForeName>
<Initials>F</Initials>
<AffiliationInfo>
<Affiliation>Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Norbäck</LastName>
<ForeName>Dan</ForeName>
<Initials>D</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Sciences, Occupational and Environmental Medicine, University of Uppsala, Uppsala, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Omenaas</LastName>
<ForeName>Ernst R</ForeName>
<Initials>ER</Initials>
<AffiliationInfo>
<Affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Rodríguez</LastName>
<ForeName>Francisco J</ForeName>
<Initials>FJ</Initials>
<AffiliationInfo>
<Affiliation>Department of Applied Mathematics, Málaga University, Málaga, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Saure</LastName>
<ForeName>Eirunn</ForeName>
<Initials>E</Initials>
<AffiliationInfo>
<Affiliation>Department of Occupational Medicine, University of Bergen, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Schlünssen</LastName>
<ForeName>Vivi</ForeName>
<Initials>V</Initials>
<AffiliationInfo>
<Affiliation>Department of Public Health, Aarhus University, Aarhus, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sigsgaard</LastName>
<ForeName>Torben</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Department of Public Health, Aarhus University, Aarhus, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Skorge</LastName>
<ForeName>Trude D</ForeName>
<Initials>TD</Initials>
<AffiliationInfo>
<Affiliation>Department of Occupational Medicine, University of Bergen, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wieslander</LastName>
<ForeName>Gunilla</ForeName>
<Initials>G</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Sciences, Occupational and Environmental Medicine, University of Uppsala, Uppsala, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Zemp</LastName>
<ForeName>Elisabeth</ForeName>
<Initials>E</Initials>
<AffiliationInfo>
<Affiliation>Department of Public Health and Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Svanes</LastName>
<ForeName>Cecilie</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Department of Occupational Medicine, University of Bergen, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Hustad</LastName>
<ForeName>Steinar</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway; Core Facility for Metabolomics, University of Bergen, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Gómez Real</LastName>
<ForeName>Francisco</ForeName>
<Initials>F</Initials>
<AffiliationInfo>
<Affiliation>Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016448">Multicenter Study</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic">
<Year>2015</Year>
<Month>10</Month>
<Day>02</Day>
</ArticleDate>
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<Country>United States</Country>
<MedlineTA>J Allergy Clin Immunol</MedlineTA>
<NlmUniqueID>1275002</NlmUniqueID>
<ISSNLinking>0091-6749</ISSNLinking>
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<RegistryNumber>4TI98Z838E</RegistryNumber>
<NameOfSubstance UI="D004958">Estradiol</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000375" MajorTopicYN="N">Aging</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D001249" MajorTopicYN="N">Asthma</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D004958" MajorTopicYN="N">Estradiol</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005060" MajorTopicYN="N" Type="Geographic">Europe</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008137" MajorTopicYN="N">Longitudinal Studies</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008593" MajorTopicYN="Y">Menopause</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D016017" MajorTopicYN="N">Odds Ratio</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">Amenorrhea</Keyword>
<Keyword MajorTopicYN="N">Respiratory Health in Northern Europe</Keyword>
<Keyword MajorTopicYN="N">asthma</Keyword>
<Keyword MajorTopicYN="N">estrogens</Keyword>
<Keyword MajorTopicYN="N">longitudinal</Keyword>
<Keyword MajorTopicYN="N">menopausal asthma</Keyword>
<Keyword MajorTopicYN="N">menopause</Keyword>
<Keyword MajorTopicYN="N">reproductive aging</Keyword>
<Keyword MajorTopicYN="N">respiratory symptoms</Keyword>
<Keyword MajorTopicYN="N">sex hormones</Keyword>
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