Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.
Identifieur interne : 002209 ( PubMed/Curation ); précédent : 002208; suivant : 002210Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.
Auteurs : Valentina Silvestri [Italie] ; Daniel Barrowdale [Royaume-Uni] ; Anna Marie Mulligan [Canada] ; Susan L. Neuhausen [États-Unis] ; Stephen Fox [Australie] ; Beth Y. Karlan [États-Unis] ; Gillian Mitchell [Australie] ; Paul James [Australie] ; Darcy L. Thull [États-Unis] ; Kristin K. Zorn [États-Unis] ; Natalie J. Carter [États-Unis] ; Katherine L. Nathanson [États-Unis] ; Susan M. Domchek [États-Unis] ; Timothy R. Rebbeck [États-Unis] ; Susan J. Ramus [États-Unis] ; Robert L. Nussbaum [États-Unis] ; Olufunmilayo I. Olopade [États-Unis] ; Johanna Rantala [Suède] ; Sook-Yee Yoon [Malaisie] ; Maria A. Caligo [Italie] ; Laura Spugnesi [Italie] ; Anders Bojesen [Danemark] ; Inge Sokilde Pedersen [Danemark] ; Mads Thomassen [Danemark] ; Uffe Birk Jensen [Danemark] ; Amanda Ewart Toland [États-Unis] ; Leigha Senter [États-Unis] ; Irene L. Andrulis [Canada] ; Gord Glendon [Canada] ; Peter J. Hulick [États-Unis] ; Evgeny N. Imyanitov [Russie] ; Mark H. Greene [États-Unis] ; Phuong L. Mai [États-Unis] ; Christian F. Singer [Autriche] ; Christine Rappaport-Fuerhauser [Autriche] ; Gero Kramer [Autriche] ; Joseph Vijai [États-Unis] ; Kenneth Offit [États-Unis] ; Mark Robson [États-Unis] ; Anne Lincoln [États-Unis] ; Lauren Jacobs [États-Unis] ; Eva Machackova [République tchèque] ; Lenka Foretova [République tchèque] ; Marie Navratilova [République tchèque] ; Petra Vasickova [République tchèque] ; Fergus J. Couch [États-Unis] ; Emily Hallberg [États-Unis] ; Kathryn J. Ruddy [États-Unis] ; Priyanka Sharma [États-Unis] ; Sung-Won Kim [Corée du Sud] ; Manuel R. Teixeira [Portugal] ; Pedro Pinto [Portugal] ; Marco Montagna [Italie] ; Laura Matricardi [Italie] ; Adalgeir Arason [Islande] ; Oskar Th Johannsson [Islande] ; Rosa B. Barkardottir [Islande] ; Anna Jakubowska [Pologne] ; Jan Lubinski [Pologne] ; Angel Izquierdo [Espagne] ; Miguel Angel Pujana [Espagne] ; Judith Balma A [Espagne] ; Orland Diez [Espagne] ; Gabriella Ivady [Hongrie] ; Janos Papp [Hongrie] ; Edith Olah [Hongrie] ; Ava Kwong [République populaire de Chine] ; Heli Nevanlinna [Finlande] ; Kristiina Aittom Ki [Finlande] ; Pedro Perez Segura [Espagne] ; Trinidad Caldes [Espagne] ; Tom Van Maerken [Belgique] ; Bruce Poppe [Belgique] ; Kathleen B M. Claes [Belgique] ; Claudine Isaacs [États-Unis] ; Camille Elan [France] ; Christine Lasset [France] ; Dominique Stoppa-Lyonnet [France] ; Laure Barjhoux [France] ; Muriel Belotti [France] ; Alfons Meindl [Allemagne] ; Andrea Gehrig [Allemagne] ; Christian Sutter [Allemagne] ; Christoph Engel [Allemagne] ; Dieter Niederacher [Allemagne] ; Doris Steinemann [Allemagne] ; Eric Hahnen [Allemagne] ; Karin Kast [Allemagne] ; Norbert Arnold [Allemagne] ; Raymonda Varon-Mateeva [Allemagne] ; Dorothea Wand [Allemagne] ; Andrew K. Godwin [États-Unis] ; D Gareth Evans [Royaume-Uni] ; Debra Frost [Royaume-Uni] ; Jo Perkins [Royaume-Uni] ; Julian Adlard [Royaume-Uni] ; Louise Izatt [Royaume-Uni] ; Radka Platte [Royaume-Uni] ; Ros Eeles [Allemagne] ; Steve Ellis [Royaume-Uni] ; Ute Hamann [Allemagne] ; Judy Garber [États-Unis] ; Florentia Fostira [Grèce] ; George Fountzilas [Grèce] ; Barbara Pasini [Italie] ; Giuseppe Giannini [Italie] ; Piera Rizzolo [Italie] ; Antonio Russo [Italie] ; Laura Cortesi [Italie] ; Laura Papi [Italie] ; Liliana Varesco [Italie] ; Domenico Palli [Italie] ; Ines Zanna [Italie] ; Antonella Savarese [Italie] ; Paolo Radice [Italie] ; Siranoush Manoukian [Italie] ; Bernard Peissel [Italie] ; Monica Barile [Italie] ; Bernardo Bonanni [Italie] ; Alessandra Viel [Italie] ; Valeria Pensotti [Italie] ; Stefania Tommasi [Italie] ; Paolo Peterlongo [Italie] ; Jeffrey N. Weitzel [États-Unis] ; Ana Osorio [Espagne] ; Javier Benitez [Espagne] ; Lesley Mcguffog [Royaume-Uni] ; Sue Healey [Australie] ; Anne-Marie Gerdes [Danemark] ; Bent Ejlertsen [Danemark] ; Thomas V O. Hansen [Danemark] ; Linda Steele [États-Unis] ; Yuan Chun Ding [États-Unis] ; Nadine Tung [États-Unis] ; Ramunas Janavicius [Lituanie] ; David E. Goldgar [États-Unis] ; Saundra S. Buys [États-Unis] ; Mary B. Daly [États-Unis] ; Anita Bane [Canada] ; Mary Beth Terry [États-Unis] ; Esther M. John [États-Unis] ; Melissa Southey [Australie] ; Douglas F. Easton [Royaume-Uni] ; Georgia Chenevix-Trench [Australie] ; Antonis C. Antoniou [Royaume-Uni] ; Laura Ottini [Italie]Source :
- Breast cancer research : BCR [ 1465-542X ] ; 2016.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mutation, Mâle, Polymorphisme de nucléotide simple, Protéine BRCA1 (génétique), Protéine BRCA2 (génétique), Prédisposition génétique à une maladie, Stade de la tumeur, Sujet âgé, Tumeur du sein de l'homme (anatomopathologie), Tumeur du sein de l'homme (génétique), Tumeurs du sein (anatomopathologie), Tumeurs du sein (génétique).
- MESH :
- anatomopathologie : Tumeur du sein de l'homme, Tumeurs du sein.
- génétique : Protéine BRCA1, Protéine BRCA2, Tumeur du sein de l'homme, Tumeurs du sein.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mutation, Mâle, Polymorphisme de nucléotide simple, Prédisposition génétique à une maladie, Stade de la tumeur, Sujet âgé.
English descriptors
- KwdEn :
- Adult, Aged, BRCA1 Protein (genetics), BRCA2 Protein (genetics), Breast Neoplasms (genetics), Breast Neoplasms (pathology), Breast Neoplasms, Male (genetics), Breast Neoplasms, Male (pathology), Female, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Mutation, Neoplasm Staging, Polymorphism, Single Nucleotide.
- MESH :
- chemical , genetics : BRCA1 Protein, BRCA2 Protein.
- genetics : Breast Neoplasms, Breast Neoplasms, Male.
- pathology : Breast Neoplasms, Breast Neoplasms, Male.
- Adult, Aged, Female, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Mutation, Neoplasm Staging, Polymorphism, Single Nucleotide.
Abstract
BRCA1 and, more commonly, BRCA2 mutations are associated with increased risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of breast cancers (BCs) in men with BRCA1/2 mutations. Using the largest available dataset, we determined whether MBCs arising in BRCA1/2 mutation carriers display specific pathologic features and whether these features differ from those of BRCA1/2 female BCs (FBCs).
DOI: 10.1186/s13058-016-0671-y
PubMed: 26857456
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Neuhausen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. sneuhausen@coh.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA</wicri:regionArea></affiliation></author><author><name sortKey="Fox, Stephen" sort="Fox, Stephen" uniqKey="Fox S" first="Stephen" last="Fox">Stephen Fox</name><affiliation wicri:level="1"><nlm:affiliation>Peter MacCallum Cancer Institute, East Melbourne, Australia. stephen.fox@petermac.org.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Peter MacCallum Cancer Institute, East Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y" last="Karlan">Beth Y. Karlan</name><affiliation wicri:level="1"><nlm:affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. beth.karlan@cshs.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA</wicri:regionArea></affiliation></author><author><name sortKey="Mitchell, Gillian" sort="Mitchell, Gillian" uniqKey="Mitchell G" first="Gillian" last="Mitchell">Gillian Mitchell</name><affiliation wicri:level="1"><nlm:affiliation>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia. gillian.mitchell@petermac.org.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="James, Paul" sort="James, Paul" uniqKey="James P" first="Paul" last="James">Paul James</name><affiliation wicri:level="1"><nlm:affiliation>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia. paul.james@petermac.org.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Thull, Darcy L" sort="Thull, Darcy L" uniqKey="Thull D" first="Darcy L" last="Thull">Darcy L. Thull</name><affiliation wicri:level="1"><nlm:affiliation>University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. dthull@magee.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh School of Medicine, Pittsburgh, PA</wicri:regionArea></affiliation></author><author><name sortKey="Zorn, Kristin K" sort="Zorn, Kristin K" uniqKey="Zorn K" first="Kristin K" last="Zorn">Kristin K. Zorn</name><affiliation wicri:level="1"><nlm:affiliation>University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. kkzorn@uams.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh School of Medicine, Pittsburgh, PA</wicri:regionArea></affiliation></author><author><name sortKey="Carter, Natalie J" sort="Carter, Natalie J" uniqKey="Carter N" first="Natalie J" last="Carter">Natalie J. Carter</name><affiliation wicri:level="1"><nlm:affiliation>UPMC Cancer Center, Pittsburgh, PA, USA. engeln@upmc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>UPMC Cancer Center, Pittsburgh, PA</wicri:regionArea></affiliation></author><author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L" last="Nathanson">Katherine L. Nathanson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA. knathans@exchange.upenn.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M" last="Domchek">Susan M. Domchek</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA. susan.domchek@uphs.upenn.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Rebbeck, Timothy R" sort="Rebbeck, Timothy R" uniqKey="Rebbeck T" first="Timothy R" last="Rebbeck">Timothy R. Rebbeck</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. rebbeck@exchange.upenn.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J" last="Ramus">Susan J. Ramus</name><affiliation wicri:level="1"><nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA. sramus@usc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA</wicri:regionArea></affiliation></author><author><name sortKey="Nussbaum, Robert L" sort="Nussbaum, Robert L" uniqKey="Nussbaum R" first="Robert L" last="Nussbaum">Robert L. Nussbaum</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine and Genetics, University of California, San Francisco, San Francisco, CA, USA. nussbaumr@humgen.ucsf.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine and Genetics, University of California, San Francisco, San Francisco, CA</wicri:regionArea></affiliation></author><author><name sortKey="Olopade, Olufunmilayo I" sort="Olopade, Olufunmilayo I" uniqKey="Olopade O" first="Olufunmilayo I" last="Olopade">Olufunmilayo I. Olopade</name><affiliation wicri:level="1"><nlm:affiliation>Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, IL, USA. folopade@medicine.bsd.uchicago.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, IL</wicri:regionArea></affiliation></author><author><name sortKey="Rantala, Johanna" sort="Rantala, Johanna" uniqKey="Rantala J" first="Johanna" last="Rantala">Johanna Rantala</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden. johanna.rantala@karolinska.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Genetics, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Yoon, Sook Yee" sort="Yoon, Sook Yee" uniqKey="Yoon S" first="Sook-Yee" last="Yoon">Sook-Yee Yoon</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia. sookyee.yoon@carif.com.my.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya</wicri:regionArea></affiliation></author><author><name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A" last="Caligo">Maria A. Caligo</name><affiliation wicri:level="1"><nlm:affiliation>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa, Italy. adelaide.caligo@do.unipi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa</wicri:regionArea></affiliation></author><author><name sortKey="Spugnesi, Laura" sort="Spugnesi, Laura" uniqKey="Spugnesi L" first="Laura" last="Spugnesi">Laura Spugnesi</name><affiliation wicri:level="1"><nlm:affiliation>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa, Italy. laura.spugnesi@gmail.com.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa</wicri:regionArea></affiliation></author><author><name sortKey="Bojesen, Anders" sort="Bojesen, Anders" uniqKey="Bojesen A" first="Anders" last="Bojesen">Anders Bojesen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark. anders.bojesen@slb.regionsyddanmark.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Vejle Hospital, Vejle</wicri:regionArea></affiliation></author><author><name sortKey="Pedersen, Inge Sokilde" sort="Pedersen, Inge Sokilde" uniqKey="Pedersen I" first="Inge Sokilde" last="Pedersen">Inge Sokilde Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg, Denmark. isp@rn.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg</wicri:regionArea></affiliation></author><author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. mads.thomassen@rsyd.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Odense University Hospital, Odense C</wicri:regionArea></affiliation></author><author><name sortKey="Jensen, Uffe Birk" sort="Jensen, Uffe Birk" uniqKey="Jensen U" first="Uffe Birk" last="Jensen">Uffe Birk Jensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark. uffejens@rm.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Aarhus University Hospital, Aarhus N</wicri:regionArea></affiliation></author><author><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, The Ohio State University, Columbus, OH, USA. amanda.toland@osumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, The Ohio State University, Columbus, OH</wicri:regionArea></affiliation></author><author><name sortKey="Senter, Leigha" sort="Senter, Leigha" uniqKey="Senter L" first="Leigha" last="Senter">Leigha Senter</name><affiliation wicri:level="1"><nlm:affiliation>Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. leigha.senter@osumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, OH</wicri:regionArea></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. andrulis@lunenfeld.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON</wicri:regionArea></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation wicri:level="1"><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. gord.glendon@cancercare.on.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON</wicri:regionArea></affiliation></author><author><name sortKey="Hulick, Peter J" sort="Hulick, Peter J" uniqKey="Hulick P" first="Peter J" last="Hulick">Peter J. Hulick</name><affiliation wicri:level="1"><nlm:affiliation>Center for Medical Genetics, North Shore University Health System, Evanston, IL, USA. phulick@northshore.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Medical Genetics, North Shore University Health System, Evanston, IL</wicri:regionArea></affiliation></author><author><name sortKey="Imyanitov, Evgeny N" sort="Imyanitov, Evgeny N" uniqKey="Imyanitov E" first="Evgeny N" last="Imyanitov">Evgeny N. Imyanitov</name><affiliation wicri:level="1"><nlm:affiliation>N.N. Petrov Institute of Oncology, St. Petersburg, Russia. evgeny@imyanitov.spb.ru.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>N.N. Petrov Institute of Oncology, St. Petersburg</wicri:regionArea></affiliation></author><author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H" last="Greene">Mark H. Greene</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. greenem@mail.nih.gov.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD</wicri:regionArea></affiliation></author><author><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L" last="Mai">Phuong L. Mai</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. maip@mail.nih.gov.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD</wicri:regionArea></affiliation></author><author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F" last="Singer">Christian F. Singer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. christian.singer@meduniwien.ac.at.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Rappaport Fuerhauser, Christine" sort="Rappaport Fuerhauser, Christine" uniqKey="Rappaport Fuerhauser C" first="Christine" last="Rappaport-Fuerhauser">Christine Rappaport-Fuerhauser</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. christine.rappaport@akhwien.at.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Kramer, Gero" sort="Kramer, Gero" uniqKey="Kramer G" first="Gero" last="Kramer">Gero Kramer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Urology, Medical University of Vienna, Vienna, Austria. gero.kramer@meduniwien.ac.at.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Urology, Medical University of Vienna, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. josephv@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. offitk@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Robson, Mark" sort="Robson, Mark" uniqKey="Robson M" first="Mark" last="Robson">Mark Robson</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. robsonm@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Lincoln, Anne" sort="Lincoln, Anne" uniqKey="Lincoln A" first="Anne" last="Lincoln">Anne Lincoln</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. lincolna@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Jacobs, Lauren" sort="Jacobs, Lauren" uniqKey="Jacobs L" first="Lauren" last="Jacobs">Lauren Jacobs</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. jacobsl@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Machackova, Eva" sort="Machackova, Eva" uniqKey="Machackova E" first="Eva" last="Machackova">Eva Machackova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. emachack@mou.cz.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno</wicri:regionArea></affiliation></author><author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name><affiliation wicri:level="1"><nlm:affiliation>Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno, Czech Republic. foretova@mou.cz.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno</wicri:regionArea></affiliation></author><author><name sortKey="Navratilova, Marie" sort="Navratilova, Marie" uniqKey="Navratilova M" first="Marie" last="Navratilova">Marie Navratilova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. mnavrati@mou.cz.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno</wicri:regionArea></affiliation></author><author><name sortKey="Vasickova, Petra" sort="Vasickova, Petra" uniqKey="Vasickova P" first="Petra" last="Vasickova">Petra Vasickova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. vasickova@mou.cz.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno</wicri:regionArea></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Hallberg, Emily" sort="Hallberg, Emily" uniqKey="Hallberg E" first="Emily" last="Hallberg">Emily Hallberg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. hallberg.emily@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Ruddy, Kathryn J" sort="Ruddy, Kathryn J" uniqKey="Ruddy K" first="Kathryn J" last="Ruddy">Kathryn J. Ruddy</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Mayo Clinic, Rochester, MN, USA. ruddy.kathryn@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Oncology, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Sharma, Priyanka" sort="Sharma, Priyanka" uniqKey="Sharma P" first="Priyanka" last="Sharma">Priyanka Sharma</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, KS, USA. psharma2@kumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, KS</wicri:regionArea></affiliation></author><author><name sortKey="Kim, Sung Won" sort="Kim, Sung Won" uniqKey="Kim S" first="Sung-Won" last="Kim">Sung-Won Kim</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Daerim St. Mary's Hospital, Seoul, Korea. brcakorea@gmail.com.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Surgery, Daerim St. Mary's Hospital, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Teixeira, Manuel R" sort="Teixeira, Manuel R" uniqKey="Teixeira M" first="Manuel R" last="Teixeira">Manuel R. Teixeira</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Portuguese Institute of Oncology, Porto, Portugal. manuel.teixeira@ipoporto.min-saude.pt.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Genetics, Portuguese Institute of Oncology, Porto</wicri:regionArea></affiliation></author><author><name sortKey="Pinto, Pedro" sort="Pinto, Pedro" uniqKey="Pinto P" first="Pedro" last="Pinto">Pedro Pinto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Portuguese Institute of Oncology, Porto, Portugal. pedro.pinto@ipoporto.min-saude.pt.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Genetics, Portuguese Institute of Oncology, Porto</wicri:regionArea></affiliation></author><author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua, Italy. montagna@unipd.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua</wicri:regionArea></affiliation></author><author><name sortKey="Matricardi, Laura" sort="Matricardi, Laura" uniqKey="Matricardi L" first="Laura" last="Matricardi">Laura Matricardi</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua, Italy. laura.matricardi@ioveneto.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua</wicri:regionArea></affiliation></author><author><name sortKey="Arason, Adalgeir" sort="Arason, Adalgeir" uniqKey="Arason A" first="Adalgeir" last="Arason">Adalgeir Arason</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. adalgeir@landspitali.is.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Johannsson, Oskar Th" sort="Johannsson, Oskar Th" uniqKey="Johannsson O" first="Oskar Th" last="Johannsson">Oskar Th Johannsson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland. oskarjoh@landspitali.is.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Department of Oncology, Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Barkardottir, Rosa B" sort="Barkardottir, Rosa B" uniqKey="Barkardottir R" first="Rosa B" last="Barkardottir">Rosa B. Barkardottir</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. rosa@landspitali.is.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Izquierdo, Angel" sort="Izquierdo, Angel" uniqKey="Izquierdo A" first="Angel" last="Izquierdo">Angel Izquierdo</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Counseling Unit, Hereditary Cancer Program, Biomedical Research Institute of Girona (IDIBGI), Catalan Institute of Oncology, Girona, Spain. aizquierdo@iconcologia.net.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Genetic Counseling Unit, Hereditary Cancer Program, Biomedical Research Institute of Girona (IDIBGI), Catalan Institute of Oncology, Girona</wicri:regionArea></affiliation></author><author><name sortKey="Pujana, Miguel Angel" sort="Pujana, Miguel Angel" uniqKey="Pujana M" first="Miguel Angel" last="Pujana">Miguel Angel Pujana</name><affiliation wicri:level="1"><nlm:affiliation>Breast Cancer and Systems Biology Unit, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology, Barcelona, Spain. mapujana@iconcologia.net.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Breast Cancer and Systems Biology Unit, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Balma A, Judith" sort="Balma A, Judith" uniqKey="Balma A J" first="Judith" last="Balma A">Judith Balma A</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Barcelona, Spain. jbalmana@vhebron.net.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Medical Oncology, Vall d'Hebron University Hospital, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name><affiliation wicri:level="1"><nlm:affiliation>Oncogenetics Group, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, Barcelona, Spain. odiez@vhebron.net.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Oncogenetics Group, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Ivady, Gabriella" sort="Ivady, Gabriella" uniqKey="Ivady G" first="Gabriella" last="Ivady">Gabriella Ivady</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, National Institute of Oncology, Budapest, Hungary. ivadygabi@oncol.hu.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Pathology, National Institute of Oncology, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Papp, Janos" sort="Papp, Janos" uniqKey="Papp J" first="Janos" last="Papp">Janos Papp</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. janos.papp@oncol.hu.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Molecular Genetics, National Institute of Oncology, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. e.olah@oncol.hu.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Molecular Genetics, National Institute of Oncology, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Kwong, Ava" sort="Kwong, Ava" uniqKey="Kwong A" first="Ava" last="Kwong">Ava Kwong</name><affiliation wicri:level="1"><nlm:affiliation>The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong, China. akwong@asiabreastregistry.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. heli.nevanlinna@hus.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. kristiina.aittomaki@hus.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Perez Segura, Pedro" sort="Perez Segura, Pedro" uniqKey="Perez Segura P" first="Pedro" last="Perez Segura">Pedro Perez Segura</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid, Spain. pperez.hcsc@salud.madrid.org.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Oncology, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Caldes, Trinidad" sort="Caldes, Trinidad" uniqKey="Caldes T" first="Trinidad" last="Caldes">Trinidad Caldes</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Oncology Laboratory, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid, Spain. trinidad.caldes@salud.madrid.org.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Molecular Oncology Laboratory, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Van Maerken, Tom" sort="Van Maerken, Tom" uniqKey="Van Maerken T" first="Tom" last="Van Maerken">Tom Van Maerken</name><affiliation wicri:level="1"><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. tom.vanmaerken@ugent.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Center for Medical Genetics, Ghent University, Ghent</wicri:regionArea></affiliation></author><author><name sortKey="Poppe, Bruce" sort="Poppe, Bruce" uniqKey="Poppe B" first="Bruce" last="Poppe">Bruce Poppe</name><affiliation wicri:level="1"><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. bruce.poppe@ugent.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Center for Medical Genetics, Ghent University, Ghent</wicri:regionArea></affiliation></author><author><name sortKey="Claes, Kathleen B M" sort="Claes, Kathleen B M" uniqKey="Claes K" first="Kathleen B M" last="Claes">Kathleen B M. Claes</name><affiliation wicri:level="1"><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. Kathleen.Claes@UGent.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Center for Medical Genetics, Ghent University, Ghent</wicri:regionArea></affiliation></author><author><name sortKey="Isaacs, Claudine" sort="Isaacs, Claudine" uniqKey="Isaacs C" first="Claudine" last="Isaacs">Claudine Isaacs</name><affiliation wicri:level="1"><nlm:affiliation>Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. isaacsc@georgetown.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC</wicri:regionArea></affiliation></author><author><name sortKey="Elan, Camille" sort="Elan, Camille" uniqKey="Elan C" first="Camille" last="Elan">Camille Elan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Tumour Biology, Institut Curie, Paris, France. camille.elan@curie.net.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Tumour Biology, Institut Curie, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Lasset, Christine" sort="Lasset, Christine" uniqKey="Lasset C" first="Christine" last="Lasset">Christine Lasset</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR5558, Université Lyon 1, Lyon, France. christine.lasset@lyon.unicancer.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR5558, Université Lyon 1, Lyon</wicri:regionArea></affiliation></author><author><name sortKey="Stoppa Lyonnet, Dominique" sort="Stoppa Lyonnet, Dominique" uniqKey="Stoppa Lyonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name><affiliation wicri:level="1"><nlm:affiliation>Department of Tumour Biology, Institut Curie, Paris, France. dominique.stoppa-lyonnet@curie.net.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Tumour Biology, Institut Curie, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name><affiliation wicri:level="1"><nlm:affiliation>INSERM U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Université Lyon, Lyon, France. laure.barjhoux@lyon.unicancer.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Université Lyon, Lyon</wicri:regionArea></affiliation></author><author><name sortKey="Belotti, Muriel" sort="Belotti, Muriel" uniqKey="Belotti M" first="Muriel" last="Belotti">Muriel Belotti</name><affiliation wicri:level="1"><nlm:affiliation>Department of Tumour Biology, Institut Curie, Paris, France. muriel.belotti@curie.net.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Tumour Biology, Institut Curie, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany. alfons.meindl@lrz.tu-muenchen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Technical University of Munich, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, University of Wurzburg, Wurzburg, Germany. gehrig@biozentrum.uni-wuerzburg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Wurzburg, Wurzburg</wicri:regionArea></affiliation></author><author><name sortKey="Sutter, Christian" sort="Sutter, Christian" uniqKey="Sutter C" first="Christian" last="Sutter">Christian Sutter</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany. c.sutter@med.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University Hospital Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig, Germany. christoph.engel@imise.uni-leipzig.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name><affiliation wicri:level="1"><nlm:affiliation>University of Dusseldorf, Dusseldorf, Germany. niederac@uni-duesseldorf.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Dusseldorf, Dusseldorf</wicri:regionArea></affiliation></author><author><name sortKey="Steinemann, Doris" sort="Steinemann, Doris" uniqKey="Steinemann D" first="Doris" last="Steinemann">Doris Steinemann</name><affiliation wicri:level="1"><nlm:affiliation>Hannover Medical School, Hannover, Germany. steinemann.doris@mh-hannover.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Hahnen, Eric" sort="Hahnen, Eric" uniqKey="Hahnen E" first="Eric" last="Hahnen">Eric Hahnen</name><affiliation wicri:level="1"><nlm:affiliation>Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. eric.hahnen@uk-koeln.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynecology and Obstetrics, Technical University of Dresden, Dresden, Germany. karin.kast@uniklinikum-dresden.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Obstetrics, Technical University of Dresden, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecolgy and Obstetrics, University Hospital of Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany. norbert.arnold@uksh.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecolgy and Obstetrics, University Hospital of Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel</wicri:regionArea></affiliation></author><author><name sortKey="Varon Mateeva, Raymonda" sort="Varon Mateeva, Raymonda" uniqKey="Varon Mateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, Charité, Berlin, Germany. raymonda.varon-mateeva@charite.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Charité, Berlin</wicri:regionArea></affiliation></author><author><name sortKey="Wand, Dorothea" sort="Wand, Dorothea" uniqKey="Wand D" first="Dorothea" last="Wand">Dorothea Wand</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, Leipzig, Germany. dorothea.wand@medizin.uni-leipzig.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K" last="Godwin">Andrew K. Godwin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA. agodwin@kumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS</wicri:regionArea></affiliation></author><author><name sortKey="Evans, D Gareth" sort="Evans, D Gareth" uniqKey="Evans D" first="D Gareth" last="Evans">D Gareth Evans</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK. gareth.evans@cmft.nhs.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester</wicri:regionArea></affiliation></author><author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. djsf2@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Perkins, Jo" sort="Perkins, Jo" uniqKey="Perkins J" first="Jo" last="Perkins">Jo Perkins</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. jp410@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name><affiliation wicri:level="1"><nlm:affiliation>Yorkshire Regional Genetics Service, Leeds, UK. julian.adlard@leedsth.nhs.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Yorkshire Regional Genetics Service, Leeds</wicri:regionArea></affiliation></author><author><name sortKey="Izatt, Louise" sort="Izatt, Louise" uniqKey="Izatt L" first="Louise" last="Izatt">Louise Izatt</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, UK. louise.izatt@gstt.nhs.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name><affiliation wicri:level="1"><nlm:affiliation>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK. rp356@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton</wicri:regionArea></affiliation></author><author><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. rosalind.eeles@icr.ac.uk.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Ellis, Steve" sort="Ellis, Steve" uniqKey="Ellis S" first="Steve" last="Ellis">Steve Ellis</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. steve@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Garber, Judy" sort="Garber, Judy" uniqKey="Garber J" first="Judy" last="Garber">Judy Garber</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA, USA. judy_garber@dfci.harvard.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Fostira, Florentia" sort="Fostira, Florentia" uniqKey="Fostira F" first="Florentia" last="Fostira">Florentia Fostira</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Diagnostics Laboratory, Institute of Nuclear and Radiological Sciences and Technology (INRASTES), National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece. florentia@rrp.demokritos.gr.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Molecular Diagnostics Laboratory, Institute of Nuclear and Radiological Sciences and Technology (INRASTES), National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens</wicri:regionArea></affiliation></author><author><name sortKey="Fountzilas, George" sort="Fountzilas, George" uniqKey="Fountzilas G" first="George" last="Fountzilas">George Fountzilas</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Papageorgiou Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece. fountzil@auth.gr.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Medical Oncology, Papageorgiou Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki</wicri:regionArea></affiliation></author><author><name sortKey="Pasini, Barbara" sort="Pasini, Barbara" uniqKey="Pasini B" first="Barbara" last="Pasini">Barbara Pasini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Science, University of Turin, Turin, Italy. barbara.pasini@unito.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Science, University of Turin, Turin</wicri:regionArea></affiliation></author><author><name sortKey="Giannini, Giuseppe" sort="Giannini, Giuseppe" uniqKey="Giannini G" first="Giuseppe" last="Giannini">Giuseppe Giannini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. giuseppe.giannini@uniroma1.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome</wicri:regionArea></affiliation></author><author><name sortKey="Rizzolo, Piera" sort="Rizzolo, Piera" uniqKey="Rizzolo P" first="Piera" last="Rizzolo">Piera Rizzolo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. piera.rizzolo@uniroma1.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome</wicri:regionArea></affiliation></author><author><name sortKey="Russo, Antonio" sort="Russo, Antonio" uniqKey="Russo A" first="Antonio" last="Russo">Antonio Russo</name><affiliation wicri:level="1"><nlm:affiliation>Section of Medical Oncology, Department of Surgical and Oncological Sciences, University of Palermo, Palermo, Italy. lab-oncobiologia@usa.net.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Medical Oncology, Department of Surgical and Oncological Sciences, University of Palermo, Palermo</wicri:regionArea></affiliation></author><author><name sortKey="Cortesi, Laura" sort="Cortesi, Laura" uniqKey="Cortesi L" first="Laura" last="Cortesi">Laura Cortesi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy. hbc@unimore.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena</wicri:regionArea></affiliation></author><author><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy. laura.papi@unifi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Varesco, Liliana" sort="Varesco, Liliana" uniqKey="Varesco L" first="Liliana" last="Varesco">Liliana Varesco</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Scientific Institute of Hospitalization and Care), AOU San Martino - IST National Institute for Cancer Research, Genoa, Italy. liliana.varesco@hsanmartino.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Scientific Institute of Hospitalization and Care), AOU San Martino - IST National Institute for Cancer Research, Genoa</wicri:regionArea></affiliation></author><author><name sortKey="Palli, Domenico" sort="Palli, Domenico" uniqKey="Palli D" first="Domenico" last="Palli">Domenico Palli</name><affiliation wicri:level="1"><nlm:affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy. d.palli@ispo.toscana.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence</wicri:regionArea></affiliation></author><author><name sortKey="Zanna, Ines" sort="Zanna, Ines" uniqKey="Zanna I" first="Ines" last="Zanna">Ines Zanna</name><affiliation wicri:level="1"><nlm:affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy. i.zanna@ispo.toscana.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence</wicri:regionArea></affiliation></author><author><name sortKey="Savarese, Antonella" sort="Savarese, Antonella" uniqKey="Savarese A" first="Antonella" last="Savarese">Antonella Savarese</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Genetic Counselling, Medical Oncology Department, Regina Elena National Cancer Institute, Rome, Italy. savarese@ifo.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Genetic Counselling, Medical Oncology Department, Regina Elena National Cancer Institute, Rome</wicri:regionArea></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), 20133, Milan, Italy. paolo.radice@istitutotumori.mi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), 20133, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan, Italy. siranoush.manoukian@istitutotumori.mi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan, Italy. bernard.peissel@istitutotumori.mi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan, Italy. monica.barile@ieo.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Bonanni, Bernardo" sort="Bonanni, Bernardo" uniqKey="Bonanni B" first="Bernardo" last="Bonanni">Bernardo Bonanni</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan, Italy. bernardo.bonanni@ieo.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Viel, Alessandra" sort="Viel, Alessandra" uniqKey="Viel A" first="Alessandra" last="Viel">Alessandra Viel</name><affiliation wicri:level="1"><nlm:affiliation>Division of Experimental Oncology, CRO Aviano National Cancer Institute, Aviano, PN, Italy. aviel@cro.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Experimental Oncology, CRO Aviano National Cancer Institute, Aviano, PN</wicri:regionArea></affiliation></author><author><name sortKey="Pensotti, Valeria" sort="Pensotti, Valeria" uniqKey="Pensotti V" first="Valeria" last="Pensotti">Valeria Pensotti</name><affiliation wicri:level="1"><nlm:affiliation>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. valeria.pensotti@ifom.eu.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Tommasi, Stefania" sort="Tommasi, Stefania" uniqKey="Tommasi S" first="Stefania" last="Tommasi">Stefania Tommasi</name><affiliation wicri:level="1"><nlm:affiliation>National Cancer Institute "Giovanni Paolo II", Bari, Italy. s.tommasi@oncologico.bari.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>National Cancer Institute "Giovanni Paolo II", Bari</wicri:regionArea></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="1"><nlm:affiliation>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. paolo.peterlongo@ifom.eu.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Weitzel, Jeffrey N" sort="Weitzel, Jeffrey N" uniqKey="Weitzel J" first="Jeffrey N" last="Weitzel">Jeffrey N. Weitzel</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, CA, USA. jweitzel@coh.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, CA</wicri:regionArea></affiliation></author><author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name><affiliation wicri:level="1"><nlm:affiliation>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), Madrid, Spain. aosorio@cnio.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation wicri:level="1"><nlm:affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. jbenitez@cnio.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Biomedical Network on Rare Diseases (CIBERER), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. lesley@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia. sue.healey@qimrberghofer.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Gerdes, Anne Marie" sort="Gerdes, Anne Marie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. anne-marie.gerdes@regionh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. bent.ejlertsen@regionh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V O" last="Hansen">Thomas V O. Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. tvoh@rh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Steele, Linda" sort="Steele, Linda" uniqKey="Steele L" first="Linda" last="Steele">Linda Steele</name><affiliation wicri:level="1"><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. lsteele@coh.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA</wicri:regionArea></affiliation></author><author><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name><affiliation wicri:level="1"><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. ycding@coh.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA</wicri:regionArea></affiliation></author><author><name sortKey="Tung, Nadine" sort="Tung, Nadine" uniqKey="Tung N" first="Nadine" last="Tung">Nadine Tung</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA. ntung@bidmc.harvard.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name><affiliation wicri:level="1"><nlm:affiliation>State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania. ramunas.janavicius@santa.lt.</nlm:affiliation><country xml:lang="fr">Lituanie</country><wicri:regionArea>State Research Institute Centre for Innovative Medicine, Vilnius</wicri:regionArea></affiliation></author><author><name sortKey="Goldgar, David E" sort="Goldgar, David E" uniqKey="Goldgar D" first="David E" last="Goldgar">David E. Goldgar</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA. david.goldgar@hsc.utah.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT</wicri:regionArea></affiliation></author><author><name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S" last="Buys">Saundra S. Buys</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA. saundra.buys@hci.utah.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT</wicri:regionArea></affiliation></author><author><name sortKey="Daly, Mary B" sort="Daly, Mary B" uniqKey="Daly M" first="Mary B" last="Daly">Mary B. Daly</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA. mary.daly@fccc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Bane, Anita" sort="Bane, Anita" uniqKey="Bane A" first="Anita" last="Bane">Anita Bane</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology & Molecular Medicine, Juravinski Hospital and Cancer Centre, McMaster University, Hamilton, ON, Canada. bane@hhsc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Pathology & Molecular Medicine, Juravinski Hospital and Cancer Centre, McMaster University, Hamilton, ON</wicri:regionArea></affiliation></author><author><name sortKey="Terry, Mary Beth" sort="Terry, Mary Beth" uniqKey="Terry M" first="Mary Beth" last="Terry">Mary Beth Terry</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA. mt146@cumc.columbia.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M" last="John">Esther M. John</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA, USA. esther.john@cpic.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA</wicri:regionArea></affiliation></author><author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia. msouthey@unimelb.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville</wicri:regionArea></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. douglas@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia. georgia.trench@qimrberghofer.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C" last="Antoniou">Antonis C. Antoniou</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. antonis@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Ottini, Laura" sort="Ottini, Laura" uniqKey="Ottini L" first="Laura" last="Ottini">Laura Ottini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. laura.ottini@uniroma1.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26857456</idno><idno type="pmid">26857456</idno><idno type="doi">10.1186/s13058-016-0671-y</idno><idno type="wicri:Area/PubMed/Corpus">002235</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002235</idno><idno type="wicri:Area/PubMed/Curation">002209</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002209</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.</title><author><name sortKey="Silvestri, Valentina" sort="Silvestri, Valentina" uniqKey="Silvestri V" first="Valentina" last="Silvestri">Valentina Silvestri</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. valentina.silvestri@uniroma1.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome</wicri:regionArea></affiliation></author><author><name sortKey="Barrowdale, Daniel" sort="Barrowdale, Daniel" uniqKey="Barrowdale D" first="Daniel" last="Barrowdale">Daniel Barrowdale</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. daniel@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory Medicine Program, University Health Network, Toronto, ON, Canada. annamarie.mulligan@uhn.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Laboratory Medicine Program, University Health Network, Toronto, ON</wicri:regionArea></affiliation></author><author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L" last="Neuhausen">Susan L. Neuhausen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. sneuhausen@coh.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA</wicri:regionArea></affiliation></author><author><name sortKey="Fox, Stephen" sort="Fox, Stephen" uniqKey="Fox S" first="Stephen" last="Fox">Stephen Fox</name><affiliation wicri:level="1"><nlm:affiliation>Peter MacCallum Cancer Institute, East Melbourne, Australia. stephen.fox@petermac.org.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Peter MacCallum Cancer Institute, East Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y" last="Karlan">Beth Y. Karlan</name><affiliation wicri:level="1"><nlm:affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. beth.karlan@cshs.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA</wicri:regionArea></affiliation></author><author><name sortKey="Mitchell, Gillian" sort="Mitchell, Gillian" uniqKey="Mitchell G" first="Gillian" last="Mitchell">Gillian Mitchell</name><affiliation wicri:level="1"><nlm:affiliation>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia. gillian.mitchell@petermac.org.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="James, Paul" sort="James, Paul" uniqKey="James P" first="Paul" last="James">Paul James</name><affiliation wicri:level="1"><nlm:affiliation>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia. paul.james@petermac.org.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Thull, Darcy L" sort="Thull, Darcy L" uniqKey="Thull D" first="Darcy L" last="Thull">Darcy L. Thull</name><affiliation wicri:level="1"><nlm:affiliation>University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. dthull@magee.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh School of Medicine, Pittsburgh, PA</wicri:regionArea></affiliation></author><author><name sortKey="Zorn, Kristin K" sort="Zorn, Kristin K" uniqKey="Zorn K" first="Kristin K" last="Zorn">Kristin K. Zorn</name><affiliation wicri:level="1"><nlm:affiliation>University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. kkzorn@uams.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh School of Medicine, Pittsburgh, PA</wicri:regionArea></affiliation></author><author><name sortKey="Carter, Natalie J" sort="Carter, Natalie J" uniqKey="Carter N" first="Natalie J" last="Carter">Natalie J. Carter</name><affiliation wicri:level="1"><nlm:affiliation>UPMC Cancer Center, Pittsburgh, PA, USA. engeln@upmc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>UPMC Cancer Center, Pittsburgh, PA</wicri:regionArea></affiliation></author><author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L" last="Nathanson">Katherine L. Nathanson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA. knathans@exchange.upenn.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M" last="Domchek">Susan M. Domchek</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA. susan.domchek@uphs.upenn.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Rebbeck, Timothy R" sort="Rebbeck, Timothy R" uniqKey="Rebbeck T" first="Timothy R" last="Rebbeck">Timothy R. Rebbeck</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. rebbeck@exchange.upenn.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J" last="Ramus">Susan J. Ramus</name><affiliation wicri:level="1"><nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA. sramus@usc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA</wicri:regionArea></affiliation></author><author><name sortKey="Nussbaum, Robert L" sort="Nussbaum, Robert L" uniqKey="Nussbaum R" first="Robert L" last="Nussbaum">Robert L. Nussbaum</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine and Genetics, University of California, San Francisco, San Francisco, CA, USA. nussbaumr@humgen.ucsf.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine and Genetics, University of California, San Francisco, San Francisco, CA</wicri:regionArea></affiliation></author><author><name sortKey="Olopade, Olufunmilayo I" sort="Olopade, Olufunmilayo I" uniqKey="Olopade O" first="Olufunmilayo I" last="Olopade">Olufunmilayo I. Olopade</name><affiliation wicri:level="1"><nlm:affiliation>Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, IL, USA. folopade@medicine.bsd.uchicago.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, IL</wicri:regionArea></affiliation></author><author><name sortKey="Rantala, Johanna" sort="Rantala, Johanna" uniqKey="Rantala J" first="Johanna" last="Rantala">Johanna Rantala</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden. johanna.rantala@karolinska.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Genetics, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Yoon, Sook Yee" sort="Yoon, Sook Yee" uniqKey="Yoon S" first="Sook-Yee" last="Yoon">Sook-Yee Yoon</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia. sookyee.yoon@carif.com.my.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya</wicri:regionArea></affiliation></author><author><name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A" last="Caligo">Maria A. Caligo</name><affiliation wicri:level="1"><nlm:affiliation>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa, Italy. adelaide.caligo@do.unipi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa</wicri:regionArea></affiliation></author><author><name sortKey="Spugnesi, Laura" sort="Spugnesi, Laura" uniqKey="Spugnesi L" first="Laura" last="Spugnesi">Laura Spugnesi</name><affiliation wicri:level="1"><nlm:affiliation>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa, Italy. laura.spugnesi@gmail.com.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa</wicri:regionArea></affiliation></author><author><name sortKey="Bojesen, Anders" sort="Bojesen, Anders" uniqKey="Bojesen A" first="Anders" last="Bojesen">Anders Bojesen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark. anders.bojesen@slb.regionsyddanmark.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Vejle Hospital, Vejle</wicri:regionArea></affiliation></author><author><name sortKey="Pedersen, Inge Sokilde" sort="Pedersen, Inge Sokilde" uniqKey="Pedersen I" first="Inge Sokilde" last="Pedersen">Inge Sokilde Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg, Denmark. isp@rn.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg</wicri:regionArea></affiliation></author><author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. mads.thomassen@rsyd.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Odense University Hospital, Odense C</wicri:regionArea></affiliation></author><author><name sortKey="Jensen, Uffe Birk" sort="Jensen, Uffe Birk" uniqKey="Jensen U" first="Uffe Birk" last="Jensen">Uffe Birk Jensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark. uffejens@rm.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Aarhus University Hospital, Aarhus N</wicri:regionArea></affiliation></author><author><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, The Ohio State University, Columbus, OH, USA. amanda.toland@osumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, The Ohio State University, Columbus, OH</wicri:regionArea></affiliation></author><author><name sortKey="Senter, Leigha" sort="Senter, Leigha" uniqKey="Senter L" first="Leigha" last="Senter">Leigha Senter</name><affiliation wicri:level="1"><nlm:affiliation>Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. leigha.senter@osumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, OH</wicri:regionArea></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. andrulis@lunenfeld.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON</wicri:regionArea></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation wicri:level="1"><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. gord.glendon@cancercare.on.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON</wicri:regionArea></affiliation></author><author><name sortKey="Hulick, Peter J" sort="Hulick, Peter J" uniqKey="Hulick P" first="Peter J" last="Hulick">Peter J. Hulick</name><affiliation wicri:level="1"><nlm:affiliation>Center for Medical Genetics, North Shore University Health System, Evanston, IL, USA. phulick@northshore.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Medical Genetics, North Shore University Health System, Evanston, IL</wicri:regionArea></affiliation></author><author><name sortKey="Imyanitov, Evgeny N" sort="Imyanitov, Evgeny N" uniqKey="Imyanitov E" first="Evgeny N" last="Imyanitov">Evgeny N. Imyanitov</name><affiliation wicri:level="1"><nlm:affiliation>N.N. Petrov Institute of Oncology, St. Petersburg, Russia. evgeny@imyanitov.spb.ru.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>N.N. Petrov Institute of Oncology, St. Petersburg</wicri:regionArea></affiliation></author><author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H" last="Greene">Mark H. Greene</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. greenem@mail.nih.gov.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD</wicri:regionArea></affiliation></author><author><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L" last="Mai">Phuong L. Mai</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. maip@mail.nih.gov.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD</wicri:regionArea></affiliation></author><author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F" last="Singer">Christian F. Singer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. christian.singer@meduniwien.ac.at.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Rappaport Fuerhauser, Christine" sort="Rappaport Fuerhauser, Christine" uniqKey="Rappaport Fuerhauser C" first="Christine" last="Rappaport-Fuerhauser">Christine Rappaport-Fuerhauser</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. christine.rappaport@akhwien.at.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Kramer, Gero" sort="Kramer, Gero" uniqKey="Kramer G" first="Gero" last="Kramer">Gero Kramer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Urology, Medical University of Vienna, Vienna, Austria. gero.kramer@meduniwien.ac.at.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Urology, Medical University of Vienna, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. josephv@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. offitk@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Robson, Mark" sort="Robson, Mark" uniqKey="Robson M" first="Mark" last="Robson">Mark Robson</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. robsonm@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Lincoln, Anne" sort="Lincoln, Anne" uniqKey="Lincoln A" first="Anne" last="Lincoln">Anne Lincoln</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. lincolna@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Jacobs, Lauren" sort="Jacobs, Lauren" uniqKey="Jacobs L" first="Lauren" last="Jacobs">Lauren Jacobs</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. jacobsl@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="Machackova, Eva" sort="Machackova, Eva" uniqKey="Machackova E" first="Eva" last="Machackova">Eva Machackova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. emachack@mou.cz.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno</wicri:regionArea></affiliation></author><author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name><affiliation wicri:level="1"><nlm:affiliation>Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno, Czech Republic. foretova@mou.cz.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno</wicri:regionArea></affiliation></author><author><name sortKey="Navratilova, Marie" sort="Navratilova, Marie" uniqKey="Navratilova M" first="Marie" last="Navratilova">Marie Navratilova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. mnavrati@mou.cz.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno</wicri:regionArea></affiliation></author><author><name sortKey="Vasickova, Petra" sort="Vasickova, Petra" uniqKey="Vasickova P" first="Petra" last="Vasickova">Petra Vasickova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. vasickova@mou.cz.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno</wicri:regionArea></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Hallberg, Emily" sort="Hallberg, Emily" uniqKey="Hallberg E" first="Emily" last="Hallberg">Emily Hallberg</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. hallberg.emily@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Ruddy, Kathryn J" sort="Ruddy, Kathryn J" uniqKey="Ruddy K" first="Kathryn J" last="Ruddy">Kathryn J. Ruddy</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Mayo Clinic, Rochester, MN, USA. ruddy.kathryn@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Oncology, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Sharma, Priyanka" sort="Sharma, Priyanka" uniqKey="Sharma P" first="Priyanka" last="Sharma">Priyanka Sharma</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, KS, USA. psharma2@kumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, KS</wicri:regionArea></affiliation></author><author><name sortKey="Kim, Sung Won" sort="Kim, Sung Won" uniqKey="Kim S" first="Sung-Won" last="Kim">Sung-Won Kim</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Daerim St. Mary's Hospital, Seoul, Korea. brcakorea@gmail.com.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Surgery, Daerim St. Mary's Hospital, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Teixeira, Manuel R" sort="Teixeira, Manuel R" uniqKey="Teixeira M" first="Manuel R" last="Teixeira">Manuel R. Teixeira</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Portuguese Institute of Oncology, Porto, Portugal. manuel.teixeira@ipoporto.min-saude.pt.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Genetics, Portuguese Institute of Oncology, Porto</wicri:regionArea></affiliation></author><author><name sortKey="Pinto, Pedro" sort="Pinto, Pedro" uniqKey="Pinto P" first="Pedro" last="Pinto">Pedro Pinto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Portuguese Institute of Oncology, Porto, Portugal. pedro.pinto@ipoporto.min-saude.pt.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Genetics, Portuguese Institute of Oncology, Porto</wicri:regionArea></affiliation></author><author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua, Italy. montagna@unipd.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua</wicri:regionArea></affiliation></author><author><name sortKey="Matricardi, Laura" sort="Matricardi, Laura" uniqKey="Matricardi L" first="Laura" last="Matricardi">Laura Matricardi</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua, Italy. laura.matricardi@ioveneto.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua</wicri:regionArea></affiliation></author><author><name sortKey="Arason, Adalgeir" sort="Arason, Adalgeir" uniqKey="Arason A" first="Adalgeir" last="Arason">Adalgeir Arason</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. adalgeir@landspitali.is.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Johannsson, Oskar Th" sort="Johannsson, Oskar Th" uniqKey="Johannsson O" first="Oskar Th" last="Johannsson">Oskar Th Johannsson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland. oskarjoh@landspitali.is.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Department of Oncology, Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Barkardottir, Rosa B" sort="Barkardottir, Rosa B" uniqKey="Barkardottir R" first="Rosa B" last="Barkardottir">Rosa B. Barkardottir</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. rosa@landspitali.is.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Izquierdo, Angel" sort="Izquierdo, Angel" uniqKey="Izquierdo A" first="Angel" last="Izquierdo">Angel Izquierdo</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Counseling Unit, Hereditary Cancer Program, Biomedical Research Institute of Girona (IDIBGI), Catalan Institute of Oncology, Girona, Spain. aizquierdo@iconcologia.net.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Genetic Counseling Unit, Hereditary Cancer Program, Biomedical Research Institute of Girona (IDIBGI), Catalan Institute of Oncology, Girona</wicri:regionArea></affiliation></author><author><name sortKey="Pujana, Miguel Angel" sort="Pujana, Miguel Angel" uniqKey="Pujana M" first="Miguel Angel" last="Pujana">Miguel Angel Pujana</name><affiliation wicri:level="1"><nlm:affiliation>Breast Cancer and Systems Biology Unit, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology, Barcelona, Spain. mapujana@iconcologia.net.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Breast Cancer and Systems Biology Unit, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Balma A, Judith" sort="Balma A, Judith" uniqKey="Balma A J" first="Judith" last="Balma A">Judith Balma A</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Barcelona, Spain. jbalmana@vhebron.net.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Medical Oncology, Vall d'Hebron University Hospital, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name><affiliation wicri:level="1"><nlm:affiliation>Oncogenetics Group, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, Barcelona, Spain. odiez@vhebron.net.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Oncogenetics Group, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Ivady, Gabriella" sort="Ivady, Gabriella" uniqKey="Ivady G" first="Gabriella" last="Ivady">Gabriella Ivady</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, National Institute of Oncology, Budapest, Hungary. ivadygabi@oncol.hu.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Pathology, National Institute of Oncology, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Papp, Janos" sort="Papp, Janos" uniqKey="Papp J" first="Janos" last="Papp">Janos Papp</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. janos.papp@oncol.hu.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Molecular Genetics, National Institute of Oncology, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. e.olah@oncol.hu.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Molecular Genetics, National Institute of Oncology, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Kwong, Ava" sort="Kwong, Ava" uniqKey="Kwong A" first="Ava" last="Kwong">Ava Kwong</name><affiliation wicri:level="1"><nlm:affiliation>The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong, China. akwong@asiabreastregistry.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. heli.nevanlinna@hus.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. kristiina.aittomaki@hus.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Perez Segura, Pedro" sort="Perez Segura, Pedro" uniqKey="Perez Segura P" first="Pedro" last="Perez Segura">Pedro Perez Segura</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid, Spain. pperez.hcsc@salud.madrid.org.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Oncology, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Caldes, Trinidad" sort="Caldes, Trinidad" uniqKey="Caldes T" first="Trinidad" last="Caldes">Trinidad Caldes</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Oncology Laboratory, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid, Spain. trinidad.caldes@salud.madrid.org.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Molecular Oncology Laboratory, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Van Maerken, Tom" sort="Van Maerken, Tom" uniqKey="Van Maerken T" first="Tom" last="Van Maerken">Tom Van Maerken</name><affiliation wicri:level="1"><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. tom.vanmaerken@ugent.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Center for Medical Genetics, Ghent University, Ghent</wicri:regionArea></affiliation></author><author><name sortKey="Poppe, Bruce" sort="Poppe, Bruce" uniqKey="Poppe B" first="Bruce" last="Poppe">Bruce Poppe</name><affiliation wicri:level="1"><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. bruce.poppe@ugent.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Center for Medical Genetics, Ghent University, Ghent</wicri:regionArea></affiliation></author><author><name sortKey="Claes, Kathleen B M" sort="Claes, Kathleen B M" uniqKey="Claes K" first="Kathleen B M" last="Claes">Kathleen B M. Claes</name><affiliation wicri:level="1"><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. Kathleen.Claes@UGent.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Center for Medical Genetics, Ghent University, Ghent</wicri:regionArea></affiliation></author><author><name sortKey="Isaacs, Claudine" sort="Isaacs, Claudine" uniqKey="Isaacs C" first="Claudine" last="Isaacs">Claudine Isaacs</name><affiliation wicri:level="1"><nlm:affiliation>Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. isaacsc@georgetown.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC</wicri:regionArea></affiliation></author><author><name sortKey="Elan, Camille" sort="Elan, Camille" uniqKey="Elan C" first="Camille" last="Elan">Camille Elan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Tumour Biology, Institut Curie, Paris, France. camille.elan@curie.net.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Tumour Biology, Institut Curie, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Lasset, Christine" sort="Lasset, Christine" uniqKey="Lasset C" first="Christine" last="Lasset">Christine Lasset</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR5558, Université Lyon 1, Lyon, France. christine.lasset@lyon.unicancer.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR5558, Université Lyon 1, Lyon</wicri:regionArea></affiliation></author><author><name sortKey="Stoppa Lyonnet, Dominique" sort="Stoppa Lyonnet, Dominique" uniqKey="Stoppa Lyonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name><affiliation wicri:level="1"><nlm:affiliation>Department of Tumour Biology, Institut Curie, Paris, France. dominique.stoppa-lyonnet@curie.net.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Tumour Biology, Institut Curie, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name><affiliation wicri:level="1"><nlm:affiliation>INSERM U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Université Lyon, Lyon, France. laure.barjhoux@lyon.unicancer.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Université Lyon, Lyon</wicri:regionArea></affiliation></author><author><name sortKey="Belotti, Muriel" sort="Belotti, Muriel" uniqKey="Belotti M" first="Muriel" last="Belotti">Muriel Belotti</name><affiliation wicri:level="1"><nlm:affiliation>Department of Tumour Biology, Institut Curie, Paris, France. muriel.belotti@curie.net.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Tumour Biology, Institut Curie, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany. alfons.meindl@lrz.tu-muenchen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Technical University of Munich, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, University of Wurzburg, Wurzburg, Germany. gehrig@biozentrum.uni-wuerzburg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Wurzburg, Wurzburg</wicri:regionArea></affiliation></author><author><name sortKey="Sutter, Christian" sort="Sutter, Christian" uniqKey="Sutter C" first="Christian" last="Sutter">Christian Sutter</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany. c.sutter@med.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University Hospital Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig, Germany. christoph.engel@imise.uni-leipzig.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name><affiliation wicri:level="1"><nlm:affiliation>University of Dusseldorf, Dusseldorf, Germany. niederac@uni-duesseldorf.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Dusseldorf, Dusseldorf</wicri:regionArea></affiliation></author><author><name sortKey="Steinemann, Doris" sort="Steinemann, Doris" uniqKey="Steinemann D" first="Doris" last="Steinemann">Doris Steinemann</name><affiliation wicri:level="1"><nlm:affiliation>Hannover Medical School, Hannover, Germany. steinemann.doris@mh-hannover.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Hahnen, Eric" sort="Hahnen, Eric" uniqKey="Hahnen E" first="Eric" last="Hahnen">Eric Hahnen</name><affiliation wicri:level="1"><nlm:affiliation>Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. eric.hahnen@uk-koeln.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynecology and Obstetrics, Technical University of Dresden, Dresden, Germany. karin.kast@uniklinikum-dresden.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynecology and Obstetrics, Technical University of Dresden, Dresden</wicri:regionArea></affiliation></author><author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecolgy and Obstetrics, University Hospital of Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany. norbert.arnold@uksh.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecolgy and Obstetrics, University Hospital of Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel</wicri:regionArea></affiliation></author><author><name sortKey="Varon Mateeva, Raymonda" sort="Varon Mateeva, Raymonda" uniqKey="Varon Mateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, Charité, Berlin, Germany. raymonda.varon-mateeva@charite.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Charité, Berlin</wicri:regionArea></affiliation></author><author><name sortKey="Wand, Dorothea" sort="Wand, Dorothea" uniqKey="Wand D" first="Dorothea" last="Wand">Dorothea Wand</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, Leipzig, Germany. dorothea.wand@medizin.uni-leipzig.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K" last="Godwin">Andrew K. Godwin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA. agodwin@kumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS</wicri:regionArea></affiliation></author><author><name sortKey="Evans, D Gareth" sort="Evans, D Gareth" uniqKey="Evans D" first="D Gareth" last="Evans">D Gareth Evans</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK. gareth.evans@cmft.nhs.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester</wicri:regionArea></affiliation></author><author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. djsf2@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Perkins, Jo" sort="Perkins, Jo" uniqKey="Perkins J" first="Jo" last="Perkins">Jo Perkins</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. jp410@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name><affiliation wicri:level="1"><nlm:affiliation>Yorkshire Regional Genetics Service, Leeds, UK. julian.adlard@leedsth.nhs.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Yorkshire Regional Genetics Service, Leeds</wicri:regionArea></affiliation></author><author><name sortKey="Izatt, Louise" sort="Izatt, Louise" uniqKey="Izatt L" first="Louise" last="Izatt">Louise Izatt</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, UK. louise.izatt@gstt.nhs.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name><affiliation wicri:level="1"><nlm:affiliation>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK. rp356@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton</wicri:regionArea></affiliation></author><author><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. rosalind.eeles@icr.ac.uk.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Ellis, Steve" sort="Ellis, Steve" uniqKey="Ellis S" first="Steve" last="Ellis">Steve Ellis</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. steve@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Garber, Judy" sort="Garber, Judy" uniqKey="Garber J" first="Judy" last="Garber">Judy Garber</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA, USA. judy_garber@dfci.harvard.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Fostira, Florentia" sort="Fostira, Florentia" uniqKey="Fostira F" first="Florentia" last="Fostira">Florentia Fostira</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Diagnostics Laboratory, Institute of Nuclear and Radiological Sciences and Technology (INRASTES), National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece. florentia@rrp.demokritos.gr.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Molecular Diagnostics Laboratory, Institute of Nuclear and Radiological Sciences and Technology (INRASTES), National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens</wicri:regionArea></affiliation></author><author><name sortKey="Fountzilas, George" sort="Fountzilas, George" uniqKey="Fountzilas G" first="George" last="Fountzilas">George Fountzilas</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Papageorgiou Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece. fountzil@auth.gr.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Medical Oncology, Papageorgiou Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki</wicri:regionArea></affiliation></author><author><name sortKey="Pasini, Barbara" sort="Pasini, Barbara" uniqKey="Pasini B" first="Barbara" last="Pasini">Barbara Pasini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Science, University of Turin, Turin, Italy. barbara.pasini@unito.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Science, University of Turin, Turin</wicri:regionArea></affiliation></author><author><name sortKey="Giannini, Giuseppe" sort="Giannini, Giuseppe" uniqKey="Giannini G" first="Giuseppe" last="Giannini">Giuseppe Giannini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. giuseppe.giannini@uniroma1.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome</wicri:regionArea></affiliation></author><author><name sortKey="Rizzolo, Piera" sort="Rizzolo, Piera" uniqKey="Rizzolo P" first="Piera" last="Rizzolo">Piera Rizzolo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. piera.rizzolo@uniroma1.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome</wicri:regionArea></affiliation></author><author><name sortKey="Russo, Antonio" sort="Russo, Antonio" uniqKey="Russo A" first="Antonio" last="Russo">Antonio Russo</name><affiliation wicri:level="1"><nlm:affiliation>Section of Medical Oncology, Department of Surgical and Oncological Sciences, University of Palermo, Palermo, Italy. lab-oncobiologia@usa.net.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Medical Oncology, Department of Surgical and Oncological Sciences, University of Palermo, Palermo</wicri:regionArea></affiliation></author><author><name sortKey="Cortesi, Laura" sort="Cortesi, Laura" uniqKey="Cortesi L" first="Laura" last="Cortesi">Laura Cortesi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy. hbc@unimore.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena</wicri:regionArea></affiliation></author><author><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy. laura.papi@unifi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Varesco, Liliana" sort="Varesco, Liliana" uniqKey="Varesco L" first="Liliana" last="Varesco">Liliana Varesco</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Scientific Institute of Hospitalization and Care), AOU San Martino - IST National Institute for Cancer Research, Genoa, Italy. liliana.varesco@hsanmartino.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Scientific Institute of Hospitalization and Care), AOU San Martino - IST National Institute for Cancer Research, Genoa</wicri:regionArea></affiliation></author><author><name sortKey="Palli, Domenico" sort="Palli, Domenico" uniqKey="Palli D" first="Domenico" last="Palli">Domenico Palli</name><affiliation wicri:level="1"><nlm:affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy. d.palli@ispo.toscana.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence</wicri:regionArea></affiliation></author><author><name sortKey="Zanna, Ines" sort="Zanna, Ines" uniqKey="Zanna I" first="Ines" last="Zanna">Ines Zanna</name><affiliation wicri:level="1"><nlm:affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy. i.zanna@ispo.toscana.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence</wicri:regionArea></affiliation></author><author><name sortKey="Savarese, Antonella" sort="Savarese, Antonella" uniqKey="Savarese A" first="Antonella" last="Savarese">Antonella Savarese</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Genetic Counselling, Medical Oncology Department, Regina Elena National Cancer Institute, Rome, Italy. savarese@ifo.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Genetic Counselling, Medical Oncology Department, Regina Elena National Cancer Institute, Rome</wicri:regionArea></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), 20133, Milan, Italy. paolo.radice@istitutotumori.mi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), 20133, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan, Italy. siranoush.manoukian@istitutotumori.mi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan, Italy. bernard.peissel@istitutotumori.mi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan, Italy. monica.barile@ieo.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Bonanni, Bernardo" sort="Bonanni, Bernardo" uniqKey="Bonanni B" first="Bernardo" last="Bonanni">Bernardo Bonanni</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan, Italy. bernardo.bonanni@ieo.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Viel, Alessandra" sort="Viel, Alessandra" uniqKey="Viel A" first="Alessandra" last="Viel">Alessandra Viel</name><affiliation wicri:level="1"><nlm:affiliation>Division of Experimental Oncology, CRO Aviano National Cancer Institute, Aviano, PN, Italy. aviel@cro.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Experimental Oncology, CRO Aviano National Cancer Institute, Aviano, PN</wicri:regionArea></affiliation></author><author><name sortKey="Pensotti, Valeria" sort="Pensotti, Valeria" uniqKey="Pensotti V" first="Valeria" last="Pensotti">Valeria Pensotti</name><affiliation wicri:level="1"><nlm:affiliation>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. valeria.pensotti@ifom.eu.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Tommasi, Stefania" sort="Tommasi, Stefania" uniqKey="Tommasi S" first="Stefania" last="Tommasi">Stefania Tommasi</name><affiliation wicri:level="1"><nlm:affiliation>National Cancer Institute "Giovanni Paolo II", Bari, Italy. s.tommasi@oncologico.bari.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>National Cancer Institute "Giovanni Paolo II", Bari</wicri:regionArea></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="1"><nlm:affiliation>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. paolo.peterlongo@ifom.eu.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Weitzel, Jeffrey N" sort="Weitzel, Jeffrey N" uniqKey="Weitzel J" first="Jeffrey N" last="Weitzel">Jeffrey N. Weitzel</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, CA, USA. jweitzel@coh.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, CA</wicri:regionArea></affiliation></author><author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name><affiliation wicri:level="1"><nlm:affiliation>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), Madrid, Spain. aosorio@cnio.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation wicri:level="1"><nlm:affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. jbenitez@cnio.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Biomedical Network on Rare Diseases (CIBERER), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. lesley@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia. sue.healey@qimrberghofer.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Gerdes, Anne Marie" sort="Gerdes, Anne Marie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. anne-marie.gerdes@regionh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. bent.ejlertsen@regionh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V O" last="Hansen">Thomas V O. Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. tvoh@rh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Steele, Linda" sort="Steele, Linda" uniqKey="Steele L" first="Linda" last="Steele">Linda Steele</name><affiliation wicri:level="1"><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. lsteele@coh.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA</wicri:regionArea></affiliation></author><author><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name><affiliation wicri:level="1"><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. ycding@coh.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA</wicri:regionArea></affiliation></author><author><name sortKey="Tung, Nadine" sort="Tung, Nadine" uniqKey="Tung N" first="Nadine" last="Tung">Nadine Tung</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA. ntung@bidmc.harvard.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name><affiliation wicri:level="1"><nlm:affiliation>State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania. ramunas.janavicius@santa.lt.</nlm:affiliation><country xml:lang="fr">Lituanie</country><wicri:regionArea>State Research Institute Centre for Innovative Medicine, Vilnius</wicri:regionArea></affiliation></author><author><name sortKey="Goldgar, David E" sort="Goldgar, David E" uniqKey="Goldgar D" first="David E" last="Goldgar">David E. Goldgar</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA. david.goldgar@hsc.utah.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT</wicri:regionArea></affiliation></author><author><name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S" last="Buys">Saundra S. Buys</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA. saundra.buys@hci.utah.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT</wicri:regionArea></affiliation></author><author><name sortKey="Daly, Mary B" sort="Daly, Mary B" uniqKey="Daly M" first="Mary B" last="Daly">Mary B. Daly</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA. mary.daly@fccc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Bane, Anita" sort="Bane, Anita" uniqKey="Bane A" first="Anita" last="Bane">Anita Bane</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology & Molecular Medicine, Juravinski Hospital and Cancer Centre, McMaster University, Hamilton, ON, Canada. bane@hhsc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Pathology & Molecular Medicine, Juravinski Hospital and Cancer Centre, McMaster University, Hamilton, ON</wicri:regionArea></affiliation></author><author><name sortKey="Terry, Mary Beth" sort="Terry, Mary Beth" uniqKey="Terry M" first="Mary Beth" last="Terry">Mary Beth Terry</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA. mt146@cumc.columbia.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY</wicri:regionArea></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M" last="John">Esther M. John</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA, USA. esther.john@cpic.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA</wicri:regionArea></affiliation></author><author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia. msouthey@unimelb.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville</wicri:regionArea></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. douglas@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia. georgia.trench@qimrberghofer.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C" last="Antoniou">Antonis C. Antoniou</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. antonis@srl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Ottini, Laura" sort="Ottini, Laura" uniqKey="Ottini L" first="Laura" last="Ottini">Laura Ottini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. laura.ottini@uniroma1.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome</wicri:regionArea></affiliation></author></analytic><series><title level="j">Breast cancer research : BCR</title><idno type="eISSN">1465-542X</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>BRCA1 Protein (genetics)</term><term>BRCA2 Protein (genetics)</term><term>Breast Neoplasms (genetics)</term><term>Breast Neoplasms (pathology)</term><term>Breast Neoplasms, Male (genetics)</term><term>Breast Neoplasms, Male (pathology)</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mutation</term><term>Neoplasm Staging</term><term>Polymorphism, Single Nucleotide</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mutation</term><term>Mâle</term><term>Polymorphisme de nucléotide simple</term><term>Protéine BRCA1 (génétique)</term><term>Protéine BRCA2 (génétique)</term><term>Prédisposition génétique à une maladie</term><term>Stade de la tumeur</term><term>Sujet âgé</term><term>Tumeur du sein de l'homme (anatomopathologie)</term><term>Tumeur du sein de l'homme (génétique)</term><term>Tumeurs du sein (anatomopathologie)</term><term>Tumeurs du sein (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>BRCA1 Protein</term><term>BRCA2 Protein</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Tumeur du sein de l'homme</term><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Breast Neoplasms</term><term>Breast Neoplasms, Male</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéine BRCA1</term><term>Protéine BRCA2</term><term>Tumeur du sein de l'homme</term><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term><term>Breast Neoplasms, Male</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mutation</term><term>Neoplasm Staging</term><term>Polymorphism, Single Nucleotide</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mutation</term><term>Mâle</term><term>Polymorphisme de nucléotide simple</term><term>Prédisposition génétique à une maladie</term><term>Stade de la tumeur</term><term>Sujet âgé</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">BRCA1 and, more commonly, BRCA2 mutations are associated with increased risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of breast cancers (BCs) in men with BRCA1/2 mutations. Using the largest available dataset, we determined whether MBCs arising in BRCA1/2 mutation carriers display specific pathologic features and whether these features differ from those of BRCA1/2 female BCs (FBCs).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26857456</PMID><DateCreated><Year>2016</Year><Month>02</Month><Day>09</Day></DateCreated><DateCompleted><Year>2016</Year><Month>10</Month><Day>05</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1465-542X</ISSN><JournalIssue CitedMedium="Internet"><Volume>18</Volume><Issue>1</Issue><PubDate><Year>2016</Year><Month>Feb</Month><Day>09</Day></PubDate></JournalIssue><Title>Breast cancer research : BCR</Title><ISOAbbreviation>Breast Cancer Res.</ISOAbbreviation></Journal><ArticleTitle>Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.</ArticleTitle><Pagination><MedlinePgn>15</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/s13058-016-0671-y</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">BRCA1 and, more commonly, BRCA2 mutations are associated with increased risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of breast cancers (BCs) in men with BRCA1/2 mutations. Using the largest available dataset, we determined whether MBCs arising in BRCA1/2 mutation carriers display specific pathologic features and whether these features differ from those of BRCA1/2 female BCs (FBCs).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We characterised the pathologic features of 419 BRCA1/2 MBCs and, using logistic regression analysis, contrasted those with data from 9675 BRCA1/2 FBCs and with population-based data from 6351 MBCs in the Surveillance, Epidemiology, and End Results (SEER) database.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Among BRCA2 MBCs, grade significantly decreased with increasing age at diagnosis (P = 0.005). Compared with BRCA2 FBCs, BRCA2 MBCs were of significantly higher stage (P for trend = 2 × 10(-5)) and higher grade (P for trend = 0.005) and were more likely to be oestrogen receptor-positive [odds ratio (OR) 10.59; 95 % confidence interval (CI) 5.15-21.80] and progesterone receptor-positive (OR 5.04; 95 % CI 3.17-8.04). With the exception of grade, similar patterns of associations emerged when we compared BRCA1 MBCs and FBCs. BRCA2 MBCs also presented with higher grade than MBCs from the SEER database (P for trend = 4 × 10(-12)).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">On the basis of the largest series analysed to date, our results show that BRCA1/2 MBCs display distinct pathologic characteristics compared with BRCA1/2 FBCs, and we identified a specific BRCA2-associated MBC phenotype characterised by a variable suggesting greater biological aggressiveness (i.e., high histologic grade). These findings could lead to the development of gender-specific risk prediction models and guide clinical strategies appropriate for MBC management.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Silvestri</LastName><ForeName>Valentina</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. valentina.silvestri@uniroma1.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barrowdale</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. daniel@srl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mulligan</LastName><ForeName>Anna Marie</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Laboratory Medicine Program, University Health Network, Toronto, ON, Canada. annamarie.mulligan@uhn.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. annamarie.mulligan@uhn.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Neuhausen</LastName><ForeName>Susan L</ForeName><Initials>SL</Initials><AffiliationInfo><Affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. sneuhausen@coh.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>Stephen</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Peter MacCallum Cancer Institute, East Melbourne, Australia. stephen.fox@petermac.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karlan</LastName><ForeName>Beth Y</ForeName><Initials>BY</Initials><AffiliationInfo><Affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. beth.karlan@cshs.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mitchell</LastName><ForeName>Gillian</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia. gillian.mitchell@petermac.org.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia. gillian.mitchell@petermac.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>James</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Australia. paul.james@petermac.org.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia. paul.james@petermac.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thull</LastName><ForeName>Darcy L</ForeName><Initials>DL</Initials><AffiliationInfo><Affiliation>University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. dthull@magee.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zorn</LastName><ForeName>Kristin K</ForeName><Initials>KK</Initials><AffiliationInfo><Affiliation>University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. kkzorn@uams.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Carter</LastName><ForeName>Natalie J</ForeName><Initials>NJ</Initials><AffiliationInfo><Affiliation>UPMC Cancer Center, Pittsburgh, PA, USA. engeln@upmc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nathanson</LastName><ForeName>Katherine L</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA. knathans@exchange.upenn.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Domchek</LastName><ForeName>Susan M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA. susan.domchek@uphs.upenn.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rebbeck</LastName><ForeName>Timothy R</ForeName><Initials>TR</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. rebbeck@exchange.upenn.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ramus</LastName><ForeName>Susan J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA. sramus@usc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nussbaum</LastName><ForeName>Robert L</ForeName><Initials>RL</Initials><AffiliationInfo><Affiliation>Department of Medicine and Genetics, University of California, San Francisco, San Francisco, CA, USA. nussbaumr@humgen.ucsf.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olopade</LastName><ForeName>Olufunmilayo I</ForeName><Initials>OI</Initials><AffiliationInfo><Affiliation>Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, IL, USA. folopade@medicine.bsd.uchicago.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rantala</LastName><ForeName>Johanna</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden. johanna.rantala@karolinska.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yoon</LastName><ForeName>Sook-Yee</ForeName><Initials>SY</Initials><AffiliationInfo><Affiliation>Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia. sookyee.yoon@carif.com.my.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia. sookyee.yoon@carif.com.my.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Caligo</LastName><ForeName>Maria A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa, Italy. adelaide.caligo@do.unipi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spugnesi</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Section of Genetic Oncology, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa, Italy. laura.spugnesi@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bojesen</LastName><ForeName>Anders</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark. anders.bojesen@slb.regionsyddanmark.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pedersen</LastName><ForeName>Inge Sokilde</ForeName><Initials>IS</Initials><AffiliationInfo><Affiliation>Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg, Denmark. isp@rn.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thomassen</LastName><ForeName>Mads</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. mads.thomassen@rsyd.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jensen</LastName><ForeName>Uffe Birk</ForeName><Initials>UB</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark. uffejens@rm.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Toland</LastName><ForeName>Amanda Ewart</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, The Ohio State University, Columbus, OH, USA. amanda.toland@osumc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Senter</LastName><ForeName>Leigha</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Division of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. leigha.senter@osumc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Andrulis</LastName><ForeName>Irene L</ForeName><Initials>IL</Initials><AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. andrulis@lunenfeld.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. andrulis@lunenfeld.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. andrulis@lunenfeld.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Glendon</LastName><ForeName>Gord</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. gord.glendon@cancercare.on.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hulick</LastName><ForeName>Peter J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Center for Medical Genetics, North Shore University Health System, Evanston, IL, USA. phulick@northshore.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Imyanitov</LastName><ForeName>Evgeny N</ForeName><Initials>EN</Initials><AffiliationInfo><Affiliation>N.N. Petrov Institute of Oncology, St. Petersburg, Russia. evgeny@imyanitov.spb.ru.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Greene</LastName><ForeName>Mark H</ForeName><Initials>MH</Initials><AffiliationInfo><Affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. greenem@mail.nih.gov.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mai</LastName><ForeName>Phuong L</ForeName><Initials>PL</Initials><AffiliationInfo><Affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. maip@mail.nih.gov.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Singer</LastName><ForeName>Christian F</ForeName><Initials>CF</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. christian.singer@meduniwien.ac.at.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rappaport-Fuerhauser</LastName><ForeName>Christine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. christine.rappaport@akhwien.at.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kramer</LastName><ForeName>Gero</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Urology, Medical University of Vienna, Vienna, Austria. gero.kramer@meduniwien.ac.at.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vijai</LastName><ForeName>Joseph</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. josephv@mskcc.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Offit</LastName><ForeName>Kenneth</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. offitk@mskcc.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Robson</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. robsonm@mskcc.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lincoln</LastName><ForeName>Anne</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. lincolna@mskcc.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacobs</LastName><ForeName>Lauren</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. jacobsl@mskcc.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Machackova</LastName><ForeName>Eva</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. emachack@mou.cz.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Foretova</LastName><ForeName>Lenka</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno, Czech Republic. foretova@mou.cz.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Navratilova</LastName><ForeName>Marie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. mnavrati@mou.cz.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vasickova</LastName><ForeName>Petra</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. vasickova@mou.cz.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Couch</LastName><ForeName>Fergus J</ForeName><Initials>FJ</Initials><AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hallberg</LastName><ForeName>Emily</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. hallberg.emily@mayo.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ruddy</LastName><ForeName>Kathryn J</ForeName><Initials>KJ</Initials><AffiliationInfo><Affiliation>Department of Oncology, Mayo Clinic, Rochester, MN, USA. ruddy.kathryn@mayo.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sharma</LastName><ForeName>Priyanka</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, KS, USA. psharma2@kumc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Sung-Won</ForeName><Initials>SW</Initials><AffiliationInfo><Affiliation>Department of Surgery, Daerim St. Mary's Hospital, Seoul, Korea. brcakorea@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>kConFab Investigators</CollectiveName></Author><Author ValidYN="Y"><LastName>Teixeira</LastName><ForeName>Manuel R</ForeName><Initials>MR</Initials><AffiliationInfo><Affiliation>Department of Genetics, Portuguese Institute of Oncology, Porto, Portugal. manuel.teixeira@ipoporto.min-saude.pt.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal. manuel.teixeira@ipoporto.min-saude.pt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pinto</LastName><ForeName>Pedro</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Genetics, Portuguese Institute of Oncology, Porto, Portugal. pedro.pinto@ipoporto.min-saude.pt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Montagna</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua, Italy. montagna@unipd.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Matricardi</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS (Scientific Institute of Hospitalization and Care), Padua, Italy. laura.matricardi@ioveneto.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arason</LastName><ForeName>Adalgeir</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. adalgeir@landspitali.is.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johannsson</LastName><ForeName>Oskar Th</ForeName><Initials>OT</Initials><AffiliationInfo><Affiliation>Department of Oncology, Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland. oskarjoh@landspitali.is.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barkardottir</LastName><ForeName>Rosa B</ForeName><Initials>RB</Initials><AffiliationInfo><Affiliation>Department of Pathology, Landspitali University Hospital and Biomedical Centre (BMC), Faculty of Medicine, University of Iceland, Reykjavik, Iceland. rosa@landspitali.is.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jakubowska</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lubinski</LastName><ForeName>Jan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Izquierdo</LastName><ForeName>Angel</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Genetic Counseling Unit, Hereditary Cancer Program, Biomedical Research Institute of Girona (IDIBGI), Catalan Institute of Oncology, Girona, Spain. aizquierdo@iconcologia.net.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pujana</LastName><ForeName>Miguel Angel</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Breast Cancer and Systems Biology Unit, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology, Barcelona, Spain. mapujana@iconcologia.net.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Balmaña</LastName><ForeName>Judith</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Barcelona, Spain. jbalmana@vhebron.net.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Diez</LastName><ForeName>Orland</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Oncogenetics Group, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, Barcelona, Spain. odiez@vhebron.net.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ivady</LastName><ForeName>Gabriella</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Pathology, National Institute of Oncology, Budapest, Hungary. ivadygabi@oncol.hu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Papp</LastName><ForeName>Janos</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. janos.papp@oncol.hu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olah</LastName><ForeName>Edith</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary. e.olah@oncol.hu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kwong</LastName><ForeName>Ava</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong, China. akwong@asiabreastregistry.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Surgery, The University of Hong Kong, Hong Kong, China. akwong@asiabreastregistry.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON)</CollectiveName></Author><Author ValidYN="Y"><LastName>Nevanlinna</LastName><ForeName>Heli</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. heli.nevanlinna@hus.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aittomäki</LastName><ForeName>Kristiina</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. kristiina.aittomaki@hus.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perez Segura</LastName><ForeName>Pedro</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Oncology, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid, Spain. pperez.hcsc@salud.madrid.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Caldes</LastName><ForeName>Trinidad</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Molecular Oncology Laboratory, San Carlos Clinical Hospital Health Research Institute (IdISSC), San Carlos Clinical Hospital, Madrid, Spain. trinidad.caldes@salud.madrid.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Van Maerken</LastName><ForeName>Tom</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. tom.vanmaerken@ugent.be.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Poppe</LastName><ForeName>Bruce</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. bruce.poppe@ugent.be.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Claes</LastName><ForeName>Kathleen B M</ForeName><Initials>KB</Initials><AffiliationInfo><Affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium. Kathleen.Claes@UGent.be.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Isaacs</LastName><ForeName>Claudine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. isaacsc@georgetown.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Elan</LastName><ForeName>Camille</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Tumour Biology, Institut Curie, Paris, France. camille.elan@curie.net.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lasset</LastName><ForeName>Christine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>CNRS UMR5558, Université Lyon 1, Lyon, France. christine.lasset@lyon.unicancer.fr.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France. christine.lasset@lyon.unicancer.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stoppa-Lyonnet</LastName><ForeName>Dominique</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Tumour Biology, Institut Curie, Paris, France. dominique.stoppa-lyonnet@curie.net.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université Paris Descartes, Sorbonne Paris Cité, Paris, France. dominique.stoppa-lyonnet@curie.net.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barjhoux</LastName><ForeName>Laure</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>INSERM U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Université Lyon, Lyon, France. laure.barjhoux@lyon.unicancer.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Belotti</LastName><ForeName>Muriel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Tumour Biology, Institut Curie, Paris, France. muriel.belotti@curie.net.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meindl</LastName><ForeName>Alfons</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Technical University of Munich, Munich, Germany. alfons.meindl@lrz.tu-muenchen.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gehrig</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, University of Wurzburg, Wurzburg, Germany. gehrig@biozentrum.uni-wuerzburg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sutter</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany. c.sutter@med.uni-heidelberg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Engel</LastName><ForeName>Christoph</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institute for Medical Informatics, Statistics and Epidemiology University of Leipzig, Leipzig, Germany. christoph.engel@imise.uni-leipzig.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Niederacher</LastName><ForeName>Dieter</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>University of Dusseldorf, Dusseldorf, Germany. niederac@uni-duesseldorf.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steinemann</LastName><ForeName>Doris</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Hannover Medical School, Hannover, Germany. steinemann.doris@mh-hannover.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hahnen</LastName><ForeName>Eric</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. eric.hahnen@uk-koeln.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kast</LastName><ForeName>Karin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Gynecology and Obstetrics, Technical University of Dresden, Dresden, Germany. karin.kast@uniklinikum-dresden.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arnold</LastName><ForeName>Norbert</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Gynaecolgy and Obstetrics, University Hospital of Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany. norbert.arnold@uksh.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Varon-Mateeva</LastName><ForeName>Raymonda</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, Charité, Berlin, Germany. raymonda.varon-mateeva@charite.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wand</LastName><ForeName>Dorothea</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, Leipzig, Germany. dorothea.wand@medizin.uni-leipzig.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Godwin</LastName><ForeName>Andrew K</ForeName><Initials>AK</Initials><AffiliationInfo><Affiliation>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA. agodwin@kumc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>D Gareth</ForeName><Initials>DG</Initials><AffiliationInfo><Affiliation>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK. gareth.evans@cmft.nhs.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Frost</LastName><ForeName>Debra</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. djsf2@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perkins</LastName><ForeName>Jo</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. jp410@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adlard</LastName><ForeName>Julian</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Yorkshire Regional Genetics Service, Leeds, UK. julian.adlard@leedsth.nhs.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Izatt</LastName><ForeName>Louise</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, UK. louise.izatt@gstt.nhs.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Platte</LastName><ForeName>Radka</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK. rp356@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eeles</LastName><ForeName>Ros</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. rosalind.eeles@icr.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ellis</LastName><ForeName>Steve</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. steve@srl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>EMBRACE</CollectiveName></Author><Author ValidYN="Y"><LastName>Hamann</LastName><ForeName>Ute</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Garber</LastName><ForeName>Judy</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, MA, USA. judy_garber@dfci.harvard.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fostira</LastName><ForeName>Florentia</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Molecular Diagnostics Laboratory, Institute of Nuclear and Radiological Sciences and Technology (INRASTES), National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece. florentia@rrp.demokritos.gr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fountzilas</LastName><ForeName>George</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, Papageorgiou Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece. fountzil@auth.gr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pasini</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Medical Science, University of Turin, Turin, Italy. barbara.pasini@unito.it.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>AO Città della Salute e della Scienza, Turin, Italy. barbara.pasini@unito.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Giannini</LastName><ForeName>Giuseppe</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. giuseppe.giannini@uniroma1.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rizzolo</LastName><ForeName>Piera</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. piera.rizzolo@uniroma1.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Russo</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Section of Medical Oncology, Department of Surgical and Oncological Sciences, University of Palermo, Palermo, Italy. lab-oncobiologia@usa.net.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cortesi</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy. hbc@unimore.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Papi</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy. laura.papi@unifi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Varesco</LastName><ForeName>Liliana</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Scientific Institute of Hospitalization and Care), AOU San Martino - IST National Institute for Cancer Research, Genoa, Italy. liliana.varesco@hsanmartino.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Palli</LastName><ForeName>Domenico</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy. d.palli@ispo.toscana.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zanna</LastName><ForeName>Ines</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy. i.zanna@ispo.toscana.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Savarese</LastName><ForeName>Antonella</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Unit of Genetic Counselling, Medical Oncology Department, Regina Elena National Cancer Institute, Rome, Italy. savarese@ifo.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Radice</LastName><ForeName>Paolo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), 20133, Milan, Italy. paolo.radice@istitutotumori.mi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Manoukian</LastName><ForeName>Siranoush</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan, Italy. siranoush.manoukian@istitutotumori.mi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peissel</LastName><ForeName>Bernard</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, IRCCS (Scientific Institute of Hospitalization and Care), National Cancer Institute (INT), Milan, Italy. bernard.peissel@istitutotumori.mi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barile</LastName><ForeName>Monica</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan, Italy. monica.barile@ieo.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bonanni</LastName><ForeName>Bernardo</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Division of Cancer Prevention and Genetics, European Institute of Oncology (IEO), Milan, Italy. bernardo.bonanni@ieo.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Viel</LastName><ForeName>Alessandra</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Experimental Oncology, CRO Aviano National Cancer Institute, Aviano, PN, Italy. aviel@cro.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pensotti</LastName><ForeName>Valeria</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. valeria.pensotti@ifom.eu.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Cogentech Cancer Genetic Test Laboratory, Milan, Italy. valeria.pensotti@ifom.eu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tommasi</LastName><ForeName>Stefania</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>National Cancer Institute "Giovanni Paolo II", Bari, Italy. s.tommasi@oncologico.bari.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peterlongo</LastName><ForeName>Paolo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy. paolo.peterlongo@ifom.eu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weitzel</LastName><ForeName>Jeffrey N</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, CA, USA. jweitzel@coh.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Osorio</LastName><ForeName>Ana</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), Madrid, Spain. aosorio@cnio.es.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. aosorio@cnio.es.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benitez</LastName><ForeName>Javier</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. jbenitez@cnio.es.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain. jbenitez@cnio.es.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Human Genotyping (CEGEN) Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. jbenitez@cnio.es.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McGuffog</LastName><ForeName>Lesley</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. lesley@srl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Healey</LastName><ForeName>Sue</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia. sue.healey@qimrberghofer.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gerdes</LastName><ForeName>Anne-Marie</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. anne-marie.gerdes@regionh.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ejlertsen</LastName><ForeName>Bent</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. bent.ejlertsen@regionh.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hansen</LastName><ForeName>Thomas V O</ForeName><Initials>TV</Initials><AffiliationInfo><Affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. tvoh@rh.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steele</LastName><ForeName>Linda</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. lsteele@coh.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ding</LastName><ForeName>Yuan Chun</ForeName><Initials>YC</Initials><AffiliationInfo><Affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. ycding@coh.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tung</LastName><ForeName>Nadine</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA. ntung@bidmc.harvard.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Janavicius</LastName><ForeName>Ramunas</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania. ramunas.janavicius@santa.lt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goldgar</LastName><ForeName>David E</ForeName><Initials>DE</Initials><AffiliationInfo><Affiliation>Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA. david.goldgar@hsc.utah.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buys</LastName><ForeName>Saundra S</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA. saundra.buys@hci.utah.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Daly</LastName><ForeName>Mary B</ForeName><Initials>MB</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA. mary.daly@fccc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bane</LastName><ForeName>Anita</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Pathology & Molecular Medicine, Juravinski Hospital and Cancer Centre, McMaster University, Hamilton, ON, Canada. bane@hhsc.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Terry</LastName><ForeName>Mary Beth</ForeName><Initials>MB</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA. mt146@cumc.columbia.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>John</LastName><ForeName>Esther M</ForeName><Initials>EM</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Cancer Prevention Institute of California, Fremont, CA, USA. esther.john@cpic.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Southey</LastName><ForeName>Melissa</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia. msouthey@unimelb.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Easton</LastName><ForeName>Douglas F</ForeName><Initials>DF</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. douglas@srl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chenevix-Trench</LastName><ForeName>Georgia</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia. georgia.trench@qimrberghofer.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Antoniou</LastName><ForeName>Antonis C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK. antonis@srl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ottini</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy. laura.ottini@uniroma1.it.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01 CA140323</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01CA140323</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>CA128978</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United 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