Neuroendocrine Regulation of Growth Hormone Secretion.
Identifieur interne : 002144 ( PubMed/Curation ); précédent : 002143; suivant : 002145Neuroendocrine Regulation of Growth Hormone Secretion.
Auteurs : Frederik J. Steyn [Australie] ; Virginie Tolle [France] ; Chen Chen [Australie] ; Jacques Epelbaum [Australie]Source :
- Comprehensive Physiology [ 2040-4603 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Consommation alimentaire, Ghréline (métabolisme), Hormone de croissance (métabolisme), Hormone de croissance (sécrétion), Humains, Longévité, Rétrocontrôle physiologique, Système nerveux central (métabolisme), Système nerveux central (physiologie), Système neuroendocrinien (métabolisme), Système neuroendocrinien (physiologie).
- MESH :
- métabolisme : Ghréline, Hormone de croissance, Système nerveux central, Système neuroendocrinien.
- physiologie : Système nerveux central, Système neuroendocrinien.
- sécrétion : Hormone de croissance.
- Animaux, Consommation alimentaire, Humains, Longévité, Rétrocontrôle physiologique.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Ghrelin, Growth Hormone.
- metabolism : Central Nervous System, Neurosecretory Systems.
- physiology : Central Nervous System, Neurosecretory Systems.
- chemical , secretion : Growth Hormone.
- Animals, Eating, Feedback, Physiological, Humans, Longevity.
Abstract
This article reviews the main findings that emerged in the intervening years since the previous volume on hormonal control of growth in the section on the endocrine system of the Handbook of Physiology concerning the intra- and extrahypothalamic neuronal networks connecting growth hormone releasing hormone (GHRH) and somatostatin hypophysiotropic neurons and the integration between regulators of food intake/metabolism and GH release. Among these findings, the discovery of ghrelin still raises many unanswered questions. One important event was the application of deconvolution analysis to the pulsatile patterns of GH secretion in different mammalian species, including Man, according to gender, hormonal environment and ageing. Concerning this last phenomenon, a great body of evidence now supports the role of an attenuation of the GHRH/GH/Insulin-like growth factor-1 (IGF-1) axis in the control of mammalian aging.
DOI: 10.1002/cphy.c150002
PubMed: 27065166
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of the Handbook of Physiology concerning the intra- and extrahypothalamic neuronal networks connecting growth hormone releasing hormone (GHRH) and somatostatin hypophysiotropic neurons and the integration between regulators of food intake/metabolism and GH release. Among these findings, the discovery of ghrelin still raises many unanswered questions. One important event was the application of deconvolution analysis to the pulsatile patterns of GH secretion in different mammalian species, including Man, according to gender, hormonal environment and ageing. Concerning this last phenomenon, a great body of evidence now supports the role of an attenuation of the GHRH/GH/Insulin-like growth factor-1 (IGF-1) axis in the control of mammalian aging.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27065166</PMID><DateCreated><Year>2016</Year><Month>04</Month><Day>12</Day></DateCreated><DateCompleted><Year>2016</Year><Month>12</Month><Day>26</Day></DateCompleted><DateRevised><Year>2016</Year><Month>12</Month><Day>30</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2040-4603</ISSN><JournalIssue CitedMedium="Internet"><Volume>6</Volume><Issue>2</Issue><PubDate><Year>2016</Year><Month>Mar</Month><Day>15</Day></PubDate></JournalIssue><Title>Comprehensive Physiology</Title><ISOAbbreviation>Compr Physiol</ISOAbbreviation></Journal><ArticleTitle>Neuroendocrine Regulation of Growth Hormone Secretion.</ArticleTitle><Pagination><MedlinePgn>687-735</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/cphy.c150002</ELocationID><Abstract><AbstractText>This article reviews the main findings that emerged in the intervening years since the previous volume on hormonal control of growth in the section on the endocrine system of the Handbook of Physiology concerning the intra- and extrahypothalamic neuronal networks connecting growth hormone releasing hormone (GHRH) and somatostatin hypophysiotropic neurons and the integration between regulators of food intake/metabolism and GH release. Among these findings, the discovery of ghrelin still raises many unanswered questions. One important event was the application of deconvolution analysis to the pulsatile patterns of GH secretion in different mammalian species, including Man, according to gender, hormonal environment and ageing. 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