Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Identifieur interne : 001D05 ( PubMed/Curation ); précédent : 001D04; suivant : 001D06Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Auteurs : Aysu Okbay [Pays-Bas] ; Bart M L. Baselmans [Pays-Bas] ; Jan-Emmanuel De Neve [Royaume-Uni] ; Patrick Turley [États-Unis] ; Michel G. Nivard [Pays-Bas] ; Mark Alan Fontana [États-Unis] ; S Fleur W. Meddens [Pays-Bas] ; Richard Karlsson Linnér [Pays-Bas] ; Cornelius A. Rietveld [Pays-Bas] ; Jaime Derringer [États-Unis] ; Jacob Gratten [Australie] ; James J. Lee [États-Unis] ; Jimmy Z. Liu [États-Unis] ; Ronald De Vlaming [Pays-Bas] ; Tarunveer S. Ahluwalia [Danemark] ; Jadwiga Buchwald [Finlande] ; Alana Cavadino [Royaume-Uni] ; Alexis C. Frazier-Wood [États-Unis] ; Nicholas A. Furlotte [États-Unis] ; Victoria Garfield [Royaume-Uni] ; Marie Henrike Geisel [Allemagne] ; Juan R. Gonzalez [Espagne] ; Saskia Haitjema [Pays-Bas] ; Robert Karlsson [Suède] ; Sander W. Van Der Laan [Pays-Bas] ; Karl-Heinz Ladwig [Allemagne] ; Jari Lahti [Finlande] ; Sven J. Van Der Lee [Pays-Bas] ; Penelope A. Lind [Australie] ; Tian Liu [Allemagne] ; Lindsay Matteson [États-Unis] ; Evelin Mihailov [Estonie] ; Michael B. Miller [États-Unis] ; Camelia C. Minica [Pays-Bas] ; Ilja M. Nolte [Pays-Bas] ; Dennis Mook-Kanamori [Pays-Bas] ; Peter J. Van Der Most [Pays-Bas] ; Christopher Oldmeadow [Australie] ; Yong Qian [États-Unis] ; Olli Raitakari [Finlande] ; Rajesh Rawal [Allemagne] ; Anu Realo [Estonie] ; Rico Rueedi [Suisse] ; Börge Schmidt [Allemagne] ; Albert V. Smith [Islande] ; Evie Stergiakouli [Royaume-Uni] ; Toshiko Tanaka [États-Unis] ; Kent Taylor [États-Unis] ; Juho Wedenoja [Finlande] ; Juergen Wellmann [Allemagne] ; Harm-Jan Westra [États-Unis] ; Sara M. Willems [Pays-Bas] ; Wei Zhao [États-Unis] ; Najaf Amin [Pays-Bas] ; Andrew Bakshi [Australie] ; Patricia A. Boyle [États-Unis] ; Samantha Cherney [États-Unis] ; Simon R. Cox [Royaume-Uni] ; Gail Davies [Royaume-Uni] ; Oliver S P. Davis [Royaume-Uni] ; Jun Ding [États-Unis] ; Nese Direk [Pays-Bas] ; Peter Eibich [Allemagne] ; Rebecca T. Emeny [Allemagne] ; Ghazaleh Fatemifar [Royaume-Uni] ; Jessica D. Faul [États-Unis] ; Luigi Ferrucci [États-Unis] ; Andreas Forstner [Allemagne] ; Christian Gieger [Allemagne] ; Richa Gupta [Finlande] ; Tamara B. Harris [États-Unis] ; Juliette M. Harris [Royaume-Uni] ; Elizabeth G. Holliday [Australie] ; Jouke-Jan Hottenga [Pays-Bas] ; Philip L. De Jager [États-Unis] ; Marika A. Kaakinen [Royaume-Uni] ; Eero Kajantie [Finlande] ; Ville Karhunen [Finlande] ; Ivana Kolcic [Croatie] ; Meena Kumari [Royaume-Uni] ; Lenore J. Launer [États-Unis] ; Lude Franke [Pays-Bas] ; Ruifang Li-Gao [Pays-Bas] ; Marisa Koini [Autriche] ; Anu Loukola [Finlande] ; Pedro Marques-Vidal [Suisse] ; Grant W. Montgomery [Australie] ; Miriam A. Mosing [Suède] ; Lavinia Paternoster [Royaume-Uni] ; Alison Pattie [Royaume-Uni] ; Katja E. Petrovic [Autriche] ; Laura Pulkki-R Back [Finlande] ; Lydia Quaye [Royaume-Uni] ; Katri R Ikkönen [Finlande] ; Igor Rudan [Royaume-Uni] ; Rodney J. Scott [Australie] ; Jennifer A. Smith [États-Unis] ; Angelina R. Sutin [États-Unis] ; Maciej Trzaskowski [Australie] ; Anna E. Vinkhuyzen [Australie] ; Lei Yu [États-Unis] ; Delilah Zabaneh [Croatie] ; John R. Attia [Australie] ; David A. Bennett [États-Unis] ; Klaus Berger [Allemagne] ; Lars Bertram [Allemagne] ; Dorret I. Boomsma [Pays-Bas] ; Harold Snieder [Pays-Bas] ; Shun-Chiao Chang [États-Unis] ; Francesco Cucca [Italie] ; Ian J. Deary [Royaume-Uni] ; Cornelia M. Van Duijn [Pays-Bas] ; Johan G. Eriksson [Finlande] ; Ute Bültmann [Pays-Bas] ; Eco J C. De Geus [Pays-Bas] ; Patrick J F. Groenen [Pays-Bas] ; Vilmundur Gudnason [Islande] ; Torben Hansen [Danemark] ; Catharine A. Hartman [Pays-Bas] ; Claire M A. Haworth [Royaume-Uni] ; Caroline Hayward [Royaume-Uni] ; Andrew C. Heath [États-Unis] ; David A. Hinds [États-Unis] ; Elina Hyppönen [Australie] ; William G. Iacono [États-Unis] ; Marjo-Riitta J Rvelin [Royaume-Uni] ; Karl-Heinz Jöckel [Allemagne] ; Jaakko Kaprio [Finlande] ; Sharon L R. Kardia [États-Unis] ; Liisa Keltikangas-J Rvinen [Finlande] ; Peter Kraft [États-Unis] ; Laura D. Kubzansky [États-Unis] ; Terho Lehtim Ki [Finlande] ; Patrik K E. Magnusson [Suède] ; Nicholas G. Martin [Australie] ; Matt Mcgue [États-Unis] ; Andres Metspalu [Estonie] ; Melinda Mills [Royaume-Uni] ; Renée De Mutsert [Pays-Bas] ; Albertine J. Oldehinkel [Pays-Bas] ; Gerard Pasterkamp [Pays-Bas] ; Nancy L. Pedersen [Suède] ; Robert Plomin [Royaume-Uni] ; Ozren Polasek [Croatie] ; Christine Power [Australie] ; Stephen S. Rich [États-Unis] ; Frits R. Rosendaal [Pays-Bas] ; Hester M. Den Ruijter [Pays-Bas] ; David Schlessinger [États-Unis] ; Helena Schmidt [Autriche] ; Rauli Svento [Finlande] ; Reinhold Schmidt [Autriche] ; Behrooz Z. Alizadeh [Pays-Bas] ; Thorkild I A. S Rensen [Danemark] ; Tim D. Spector [Royaume-Uni] ; Andrew Steptoe [Royaume-Uni] ; Antonio Terracciano [États-Unis] ; A Roy Thurik [Pays-Bas] ; Nicholas J. Timpson [Royaume-Uni] ; Henning Tiemeier [Pays-Bas] ; André G. Uitterlinden [Pays-Bas] ; Peter Vollenweider [Suisse] ; Gert G. Wagner [Allemagne] ; David R. Weir [États-Unis] ; Jian Yang [Australie] ; Dalton C. Conley [États-Unis] ; George Davey Smith [Royaume-Uni] ; Albert Hofman [Pays-Bas] ; Magnus Johannesson [Suède] ; David I. Laibson [États-Unis] ; Sarah E. Medland [Australie] ; Michelle N. Meyer [États-Unis] ; Joseph K. Pickrell [États-Unis] ; T Nu Esko [Estonie] ; Robert F. Krueger [États-Unis] ; Jonathan P. Beauchamp [États-Unis] ; Philipp D. Koellinger [Pays-Bas] ; Daniel J. Benjamin [États-Unis] ; Meike Bartels [Pays-Bas] ; David Cesarini [États-Unis]Source :
- Nature genetics [ 1546-1718 ] ; 2016.
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Abstract
Very few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies. Subjective well-being, a phenotype that is genetically correlated with both of these traits, has not yet been studied with genome-wide data. We conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n = 161,460), and neuroticism (n = 170,911). We identify 3 variants associated with subjective well-being, 2 variants associated with depressive symptoms, and 11 variants associated with neuroticism, including 2 inversion polymorphisms. The two loci associated with depressive symptoms replicate in an independent depression sample. Joint analyses that exploit the high genetic correlations between the phenotypes (|ρ^| ≈ 0.8) strengthen the overall credibility of the findings and allow us to identify additional variants. Across our phenotypes, loci regulating expression in central nervous system and adrenal or pancreas tissues are strongly enriched for association.
DOI: 10.1038/ng.3552
PubMed: 27089181
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Gonzalez</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Research in Environmental Epidemiology, Institute for Global Health, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centre for Research in Environmental Epidemiology, Institute for Global Health, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Haitjema, Saskia" sort="Haitjema, Saskia" uniqKey="Haitjema S" first="Saskia" last="Haitjema">Saskia Haitjema</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Karlsson, Robert" sort="Karlsson, Robert" uniqKey="Karlsson R" first="Robert" last="Karlsson">Robert Karlsson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Laan, Sander W" sort="Van Der Laan, Sander W" uniqKey="Van Der Laan S" first="Sander W" last="Van Der Laan">Sander W. Van Der Laan</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Ladwig, Karl Heinz" sort="Ladwig, Karl Heinz" uniqKey="Ladwig K" first="Karl-Heinz" last="Ladwig">Karl-Heinz Ladwig</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universität München, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Lee, Sven J" sort="Van Der Lee, Sven J" uniqKey="Van Der Lee S" first="Sven J" last="Van Der Lee">Sven J. Van Der Lee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Lind, Penelope A" sort="Lind, Penelope A" uniqKey="Lind P" first="Penelope A" last="Lind">Penelope A. Lind</name><affiliation wicri:level="1"><nlm:affiliation>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Tian" sort="Liu, Tian" uniqKey="Liu T" first="Tian" last="Liu">Tian Liu</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Human Development, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Human Development, Berlin</wicri:regionArea></affiliation></author><author><name sortKey="Matteson, Lindsay" sort="Matteson, Lindsay" uniqKey="Matteson L" first="Lindsay" last="Matteson">Lindsay Matteson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Miller, Michael B" sort="Miller, Michael B" uniqKey="Miller M" first="Michael B" last="Miller">Michael B. Miller</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Minica, Camelia C" sort="Minica, Camelia C" uniqKey="Minica C" first="Camelia C" last="Minica">Camelia C. Minica</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Mook Kanamori, Dennis" sort="Mook Kanamori, Dennis" uniqKey="Mook Kanamori D" first="Dennis" last="Mook-Kanamori">Dennis Mook-Kanamori</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Clinical Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Most, Peter J" sort="Van Der Most, Peter J" uniqKey="Van Der Most P" first="Peter J" last="Van Der Most">Peter J. Van Der Most</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Oldmeadow, Christopher" sort="Oldmeadow, Christopher" uniqKey="Oldmeadow C" first="Christopher" last="Oldmeadow">Christopher Oldmeadow</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Qian, Yong" sort="Qian, Yong" uniqKey="Qian Y" first="Yong" last="Qian">Yong Qian</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Raitakari, Olli" sort="Raitakari, Olli" uniqKey="Raitakari O" first="Olli" last="Raitakari">Olli Raitakari</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Rawal, Rajesh" sort="Rawal, Rajesh" uniqKey="Rawal R" first="Rajesh" last="Rawal">Rajesh Rawal</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Realo, Anu" sort="Realo, Anu" uniqKey="Realo A" first="Anu" last="Realo">Anu Realo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Department of Psychology, University of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Rueedi, Rico" sort="Rueedi, Rico" uniqKey="Rueedi R" first="Rico" last="Rueedi">Rico Rueedi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Computational Biology, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Borge" sort="Schmidt, Borge" uniqKey="Schmidt B" first="Börge" last="Schmidt">Börge Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen</wicri:regionArea></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea></affiliation></author><author><name sortKey="Stergiakouli, Evie" sort="Stergiakouli, Evie" uniqKey="Stergiakouli E" first="Evie" last="Stergiakouli">Evie Stergiakouli</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Taylor, Kent" sort="Taylor, Kent" uniqKey="Taylor K" first="Kent" last="Taylor">Kent Taylor</name><affiliation wicri:level="1"><nlm:affiliation>Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA, Torrence, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA, Torrence, California</wicri:regionArea></affiliation></author><author><name sortKey="Wedenoja, Juho" sort="Wedenoja, Juho" uniqKey="Wedenoja J" first="Juho" last="Wedenoja">Juho Wedenoja</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Wellmann, Juergen" sort="Wellmann, Juergen" uniqKey="Wellmann J" first="Juergen" last="Wellmann">Juergen Wellmann</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology and Social Medicine, University of Münster, Münster</wicri:regionArea></affiliation></author><author><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Willems, Sara M" sort="Willems, Sara M" uniqKey="Willems S" first="Sara M" last="Willems">Sara M. Willems</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Zhao, Wei" sort="Zhao, Wei" uniqKey="Zhao W" first="Wei" last="Zhao">Wei Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Bakshi, Andrew" sort="Bakshi, Andrew" uniqKey="Bakshi A" first="Andrew" last="Bakshi">Andrew Bakshi</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Boyle, Patricia A" sort="Boyle, Patricia A" uniqKey="Boyle P" first="Patricia A" last="Boyle">Patricia A. Boyle</name><affiliation wicri:level="1"><nlm:affiliation>Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Cherney, Samantha" sort="Cherney, Samantha" uniqKey="Cherney S" first="Samantha" last="Cherney">Samantha Cherney</name><affiliation wicri:level="1"><nlm:affiliation>RAND Corporation, Santa Monica, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>RAND Corporation, Santa Monica, California</wicri:regionArea></affiliation></author><author><name sortKey="Cox, Simon R" sort="Cox, Simon R" uniqKey="Cox S" first="Simon R" last="Cox">Simon R. Cox</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Davies, Gail" sort="Davies, Gail" uniqKey="Davies G" first="Gail" last="Davies">Gail Davies</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Davis, Oliver S P" sort="Davis, Oliver S P" uniqKey="Davis O" first="Oliver S P" last="Davis">Oliver S P. Davis</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Ding, Jun" sort="Ding, Jun" uniqKey="Ding J" first="Jun" last="Ding">Jun Ding</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Direk, Nese" sort="Direk, Nese" uniqKey="Direk N" first="Nese" last="Direk">Nese Direk</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Eibich, Peter" sort="Eibich, Peter" uniqKey="Eibich P" first="Peter" last="Eibich">Peter Eibich</name><affiliation wicri:level="1"><nlm:affiliation>German Socio-Economic Panel Study, DIW Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Socio-Economic Panel Study, DIW Berlin, Berlin</wicri:regionArea></affiliation></author><author><name sortKey="Emeny, Rebecca T" sort="Emeny, Rebecca T" uniqKey="Emeny R" first="Rebecca T" last="Emeny">Rebecca T. Emeny</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II, Mental Health Research Unit, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Mental Health Research Unit, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Fatemifar, Ghazaleh" sort="Fatemifar, Ghazaleh" uniqKey="Fatemifar G" first="Ghazaleh" last="Fatemifar">Ghazaleh Fatemifar</name><affiliation wicri:level="1"><nlm:affiliation>Farr Institute of Health Informatics, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Farr Institute of Health Informatics, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Faul, Jessica D" sort="Faul, Jessica D" uniqKey="Faul J" first="Jessica D" last="Faul">Jessica D. Faul</name><affiliation wicri:level="1"><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Forstner, Andreas" sort="Forstner, Andreas" uniqKey="Forstner A" first="Andreas" last="Forstner">Andreas Forstner</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Bonn, Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Gupta, Richa" sort="Gupta, Richa" uniqKey="Gupta R" first="Richa" last="Gupta">Richa Gupta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Epidemiology, Demography, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology, Demography, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Harris, Juliette M" sort="Harris, Juliette M" uniqKey="Harris J" first="Juliette M" last="Harris">Juliette M. Harris</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Holliday, Elizabeth G" sort="Holliday, Elizabeth G" uniqKey="Holliday E" first="Elizabeth G" last="Holliday">Elizabeth G. Holliday</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><affiliation wicri:level="1"><nlm:affiliation>Program in Translational NeuroPsychiatric Genomics, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Translational NeuroPsychiatric Genomics, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Kaakinen, Marika A" sort="Kaakinen, Marika A" uniqKey="Kaakinen M" first="Marika A" last="Kaakinen">Marika A. Kaakinen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genomics of Common Disease, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genomics of Common Disease, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Kajantie, Eero" sort="Kajantie, Eero" uniqKey="Kajantie E" first="Eero" last="Kajantie">Eero Kajantie</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Pediatrics, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Karhunen, Ville" sort="Karhunen, Ville" uniqKey="Karhunen V" first="Ville" last="Karhunen">Ville Karhunen</name><affiliation wicri:level="1"><nlm:affiliation>Center for Life Course Health Research, University of Oulu and Oulu University Hospital, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Center for Life Course Health Research, University of Oulu and Oulu University Hospital, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Social and Economic Research, University of Essex, Wivenhoe Park, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Social and Economic Research, University of Essex, Wivenhoe Park</wicri:regionArea></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation wicri:level="1"><nlm:affiliation>Neuroepidemiology Section, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Neuroepidemiology Section, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Li Gao, Ruifang" sort="Li Gao, Ruifang" uniqKey="Li Gao R" first="Ruifang" last="Li-Gao">Ruifang Li-Gao</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Clinical Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Koini, Marisa" sort="Koini, Marisa" uniqKey="Koini M" first="Marisa" last="Koini">Marisa Koini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, General Hospital and Medical University Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Loukola, Anu" sort="Loukola, Anu" uniqKey="Loukola A" first="Anu" last="Loukola">Anu Loukola</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Marques Vidal, Pedro" sort="Marques Vidal, Pedro" uniqKey="Marques Vidal P" first="Pedro" last="Marques-Vidal">Pedro Marques-Vidal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Mosing, Miriam A" sort="Mosing, Miriam A" uniqKey="Mosing M" first="Miriam A" last="Mosing">Miriam A. Mosing</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Pattie, Alison" sort="Pattie, Alison" uniqKey="Pattie A" first="Alison" last="Pattie">Alison Pattie</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Petrovic, Katja E" sort="Petrovic, Katja E" uniqKey="Petrovic K" first="Katja E" last="Petrovic">Katja E. Petrovic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, General Hospital and Medical University Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Pulkki R Back, Laura" sort="Pulkki R Back, Laura" uniqKey="Pulkki R Back L" first="Laura" last="Pulkki-R Back">Laura Pulkki-R Back</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Quaye, Lydia" sort="Quaye, Lydia" uniqKey="Quaye L" first="Lydia" last="Quaye">Lydia Quaye</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="R Ikkonen, Katri" sort="R Ikkonen, Katri" uniqKey="R Ikkonen K" first="Katri" last="R Ikkönen">Katri R Ikkönen</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Scott, Rodney J" sort="Scott, Rodney J" uniqKey="Scott R" first="Rodney J" last="Scott">Rodney J. Scott</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Smith, Jennifer A" sort="Smith, Jennifer A" uniqKey="Smith J" first="Jennifer A" last="Smith">Jennifer A. Smith</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Sutin, Angelina R" sort="Sutin, Angelina R" uniqKey="Sutin A" first="Angelina R" last="Sutin">Angelina R. Sutin</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Trzaskowski, Maciej" sort="Trzaskowski, Maciej" uniqKey="Trzaskowski M" first="Maciej" last="Trzaskowski">Maciej Trzaskowski</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Vinkhuyzen, Anna E" sort="Vinkhuyzen, Anna E" uniqKey="Vinkhuyzen A" first="Anna E" last="Vinkhuyzen">Anna E. Vinkhuyzen</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Attia, John R" sort="Attia, John R" uniqKey="Attia J" first="John R" last="Attia">John R. Attia</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Berger, Klaus" sort="Berger, Klaus" uniqKey="Berger K" first="Klaus" last="Berger">Klaus Berger</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology and Social Medicine, University of Münster, Münster</wicri:regionArea></affiliation></author><author><name sortKey="Bertram, Lars" sort="Bertram, Lars" uniqKey="Bertram L" first="Lars" last="Bertram">Lars Bertram</name><affiliation wicri:level="1"><nlm:affiliation>Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institute of Neurogenetics and Institute of Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institute of Neurogenetics and Institute of Integrative and Experimental Genomics, University of Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Chang, Shun Chiao" sort="Chang, Shun Chiao" uniqKey="Chang S" first="Shun-Chiao" last="Chang">Shun-Chiao Chang</name><affiliation wicri:level="1"><nlm:affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Cucca, Francesco" sort="Cucca, Francesco" uniqKey="Cucca F" first="Francesco" last="Cucca">Francesco Cucca</name><affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cittadella Universitarià di Monserrato, Monserrato, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cittadella Universitarià di Monserrato, Monserrato</wicri:regionArea></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><affiliation wicri:level="1"><nlm:affiliation>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Bultmann, Ute" sort="Bultmann, Ute" uniqKey="Bultmann U" first="Ute" last="Bültmann">Ute Bültmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Groenen, Patrick J F" sort="Groenen, Patrick J F" uniqKey="Groenen P" first="Patrick J F" last="Groenen">Patrick J F. Groenen</name><affiliation wicri:level="1"><nlm:affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea></affiliation></author><author><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Hartman, Catharine A" sort="Hartman, Catharine A" uniqKey="Hartman C" first="Catharine A" last="Hartman">Catharine A. Hartman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Haworth, Claire M A" sort="Haworth, Claire M A" uniqKey="Haworth C" first="Claire M A" last="Haworth">Claire M A. Haworth</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="1"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Heath, Andrew C" sort="Heath, Andrew C" uniqKey="Heath A" first="Andrew C" last="Heath">Andrew C. Heath</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Hinds, David A" sort="Hinds, David A" uniqKey="Hinds D" first="David A" last="Hinds">David A. Hinds</name><affiliation wicri:level="1"><nlm:affiliation>23andMe, Inc., Mountain View, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>23andMe, Inc., Mountain View, California</wicri:regionArea></affiliation></author><author><name sortKey="Hypponen, Elina" sort="Hypponen, Elina" uniqKey="Hypponen E" first="Elina" last="Hyppönen">Elina Hyppönen</name><affiliation wicri:level="1"><nlm:affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>South Australian Health and Medical Research Institute, Adelaide, South Australia</wicri:regionArea></affiliation></author><author><name sortKey="Iacono, William G" sort="Iacono, William G" uniqKey="Iacono W" first="William G" last="Iacono">William G. Iacono</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genomics of Common Disease, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genomics of Common Disease, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen</wicri:regionArea></affiliation></author><author><name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L R" last="Kardia">Sharon L R. Kardia</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Keltikangas J Rvinen, Liisa" sort="Keltikangas J Rvinen, Liisa" uniqKey="Keltikangas J Rvinen L" first="Liisa" last="Keltikangas-J Rvinen">Liisa Keltikangas-J Rvinen</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Kubzansky, Laura D" sort="Kubzansky, Laura D" uniqKey="Kubzansky L" first="Laura D" last="Kubzansky">Laura D. Kubzansky</name><affiliation wicri:level="1"><nlm:affiliation>Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:affiliation>Fimlab Laboratories, Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Fimlab Laboratories, Tampere</wicri:regionArea></affiliation></author><author><name sortKey="Magnusson, Patrik K E" sort="Magnusson, Patrik K E" uniqKey="Magnusson P" first="Patrik K E" last="Magnusson">Patrik K E. Magnusson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Mcgue, Matt" sort="Mcgue, Matt" uniqKey="Mcgue M" first="Matt" last="Mcgue">Matt Mcgue</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Mills, Melinda" sort="Mills, Melinda" uniqKey="Mills M" first="Melinda" last="Mills">Melinda Mills</name><affiliation wicri:level="1"><nlm:affiliation>Department of Sociology, University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Sociology, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="De Mutsert, Renee" sort="De Mutsert, Renee" uniqKey="De Mutsert R" first="Renée" last="De Mutsert">Renée De Mutsert</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Clinical Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J" last="Oldehinkel">Albertine J. Oldehinkel</name><affiliation wicri:level="1"><nlm:affiliation>Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Pasterkamp, Gerard" sort="Pasterkamp, Gerard" uniqKey="Pasterkamp G" first="Gerard" last="Pasterkamp">Gerard Pasterkamp</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L" last="Pedersen">Nancy L. Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Plomin, Robert" sort="Plomin, Robert" uniqKey="Plomin R" first="Robert" last="Plomin">Robert Plomin</name><affiliation wicri:level="1"><nlm:affiliation>Social, Genetic and Developmental Psychiatry Centre, King's College London, De Crespigny Park, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic and Developmental Psychiatry Centre, King's College London, De Crespigny Park</wicri:regionArea></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Power, Christine" sort="Power, Christine" uniqKey="Power C" first="Christine" last="Power">Christine Power</name><affiliation wicri:level="1"><nlm:affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>South Australian Health and Medical Research Institute, Adelaide, South Australia</wicri:regionArea></affiliation></author><author><name sortKey="Rich, Stephen S" sort="Rich, Stephen S" uniqKey="Rich S" first="Stephen S" last="Rich">Stephen S. Rich</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia</wicri:regionArea></affiliation></author><author><name sortKey="Rosendaal, Frits R" sort="Rosendaal, Frits R" uniqKey="Rosendaal F" first="Frits R" last="Rosendaal">Frits R. Rosendaal</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Clinical Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Den Ruijter, Hester M" sort="Den Ruijter, Hester M" uniqKey="Den Ruijter H" first="Hester M" last="Den Ruijter">Hester M. Den Ruijter</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Schlessinger, David" sort="Schlessinger, David" uniqKey="Schlessinger D" first="David" last="Schlessinger">David Schlessinger</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, General Hospital and Medical University Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Svento, Rauli" sort="Svento, Rauli" uniqKey="Svento R" first="Rauli" last="Svento">Rauli Svento</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Oulu Business School, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Economics, Oulu Business School, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, General Hospital and Medical University Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Alizadeh, Behrooz Z" sort="Alizadeh, Behrooz Z" uniqKey="Alizadeh B" first="Behrooz Z" last="Alizadeh">Behrooz Z. Alizadeh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="S Rensen, Thorkild I A" sort="S Rensen, Thorkild I A" uniqKey="S Rensen T" first="Thorkild I A" last="S Rensen">Thorkild I A. S Rensen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Steptoe, Andrew" sort="Steptoe, Andrew" uniqKey="Steptoe A" first="Andrew" last="Steptoe">Andrew Steptoe</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Terracciano, Antonio" sort="Terracciano, Antonio" uniqKey="Terracciano A" first="Antonio" last="Terracciano">Antonio Terracciano</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Thurik, A Roy" sort="Thurik, A Roy" uniqKey="Thurik A" first="A Roy" last="Thurik">A Roy Thurik</name><affiliation wicri:level="1"><nlm:affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Timpson, Nicholas J" sort="Timpson, Nicholas J" uniqKey="Timpson N" first="Nicholas J" last="Timpson">Nicholas J. Timpson</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Tiemeier, Henning" sort="Tiemeier, Henning" uniqKey="Tiemeier H" first="Henning" last="Tiemeier">Henning Tiemeier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Wagner, Gert G" sort="Wagner, Gert G" uniqKey="Wagner G" first="Gert G" last="Wagner">Gert G. Wagner</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Human Development, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Human Development, Berlin</wicri:regionArea></affiliation></author><author><name sortKey="Weir, David R" sort="Weir, David R" uniqKey="Weir D" first="David R" last="Weir">David R. Weir</name><affiliation wicri:level="1"><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Jian" sort="Yang, Jian" uniqKey="Yang J" first="Jian" last="Yang">Jian Yang</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Conley, Dalton C" sort="Conley, Dalton C" uniqKey="Conley D" first="Dalton C" last="Conley">Dalton C. Conley</name><affiliation wicri:level="1"><nlm:affiliation>Department of Sociology, Princeton University, Princeton, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Sociology, Princeton University, Princeton, New Jersey</wicri:regionArea></affiliation></author><author><name sortKey="Smith, George Davey" sort="Smith, George Davey" uniqKey="Smith G" first="George Davey" last="Smith">George Davey Smith</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Johannesson, Magnus" sort="Johannesson, Magnus" uniqKey="Johannesson M" first="Magnus" last="Johannesson">Magnus Johannesson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Stockholm School of Economics, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Economics, Stockholm School of Economics, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Laibson, David I" sort="Laibson, David I" uniqKey="Laibson D" first="David I" last="Laibson">David I. Laibson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Harvard University, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Economics, Harvard University, Cambridge, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Medland, Sarah E" sort="Medland, Sarah E" uniqKey="Medland S" first="Sarah E" last="Medland">Sarah E. Medland</name><affiliation wicri:level="1"><nlm:affiliation>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Meyer, Michelle N" sort="Meyer, Michelle N" uniqKey="Meyer M" first="Michelle N" last="Meyer">Michelle N. Meyer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Bioethics, Clarkson University, Schenectady, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Bioethics, Clarkson University, Schenectady, New York</wicri:regionArea></affiliation></author><author><name sortKey="Pickrell, Joseph K" sort="Pickrell, Joseph K" uniqKey="Pickrell J" first="Joseph K" last="Pickrell">Joseph K. Pickrell</name><affiliation wicri:level="1"><nlm:affiliation>New York Genome Center, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New York Genome Center, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Krueger, Robert F" sort="Krueger, Robert F" uniqKey="Krueger R" first="Robert F" last="Krueger">Robert F. Krueger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Beauchamp, Jonathan P" sort="Beauchamp, Jonathan P" uniqKey="Beauchamp J" first="Jonathan P" last="Beauchamp">Jonathan P. Beauchamp</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Harvard University, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Economics, Harvard University, Cambridge, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Koellinger, Philipp D" sort="Koellinger, Philipp D" uniqKey="Koellinger P" first="Philipp D" last="Koellinger">Philipp D. Koellinger</name><affiliation wicri:level="1"><nlm:affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Benjamin, Daniel J" sort="Benjamin, Daniel J" uniqKey="Benjamin D" first="Daniel J" last="Benjamin">Daniel J. Benjamin</name><affiliation wicri:level="1"><nlm:affiliation>Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Economic and Social Research, University of Southern California, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Bartels, Meike" sort="Bartels, Meike" uniqKey="Bartels M" first="Meike" last="Bartels">Meike Bartels</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Cesarini, David" sort="Cesarini, David" uniqKey="Cesarini D" first="David" last="Cesarini">David Cesarini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, New York University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Economics, New York University, New York, New York</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27089181</idno><idno type="pmid">27089181</idno><idno type="doi">10.1038/ng.3552</idno><idno type="wicri:Area/PubMed/Corpus">001D29</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001D29</idno><idno type="wicri:Area/PubMed/Curation">001D05</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001D05</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.</title><author><name sortKey="Okbay, Aysu" sort="Okbay, Aysu" uniqKey="Okbay A" first="Aysu" last="Okbay">Aysu Okbay</name><affiliation wicri:level="1"><nlm:affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Baselmans, Bart M L" sort="Baselmans, Bart M L" uniqKey="Baselmans B" first="Bart M L" last="Baselmans">Bart M L. Baselmans</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="De Neve, Jan Emmanuel" sort="De Neve, Jan Emmanuel" uniqKey="De Neve J" first="Jan-Emmanuel" last="De Neve">Jan-Emmanuel De Neve</name><affiliation wicri:level="1"><nlm:affiliation>Saïd Business School, University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Saïd Business School, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Turley, Patrick" sort="Turley, Patrick" uniqKey="Turley P" first="Patrick" last="Turley">Patrick Turley</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Harvard University, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Economics, Harvard University, Cambridge, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Nivard, Michel G" sort="Nivard, Michel G" uniqKey="Nivard M" first="Michel G" last="Nivard">Michel G. Nivard</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Fontana, Mark Alan" sort="Fontana, Mark Alan" uniqKey="Fontana M" first="Mark Alan" last="Fontana">Mark Alan Fontana</name><affiliation wicri:level="1"><nlm:affiliation>Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Economic and Social Research, University of Southern California, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Meddens, S Fleur W" sort="Meddens, S Fleur W" uniqKey="Meddens S" first="S Fleur W" last="Meddens">S Fleur W. Meddens</name><affiliation wicri:level="1"><nlm:affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Linner, Richard Karlsson" sort="Linner, Richard Karlsson" uniqKey="Linner R" first="Richard Karlsson" last="Linnér">Richard Karlsson Linnér</name><affiliation wicri:level="1"><nlm:affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Rietveld, Cornelius A" sort="Rietveld, Cornelius A" uniqKey="Rietveld C" first="Cornelius A" last="Rietveld">Cornelius A. Rietveld</name><affiliation wicri:level="1"><nlm:affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Derringer, Jaime" sort="Derringer, Jaime" uniqKey="Derringer J" first="Jaime" last="Derringer">Jaime Derringer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Illinois, Champaign, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Illinois, Champaign, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Gratten, Jacob" sort="Gratten, Jacob" uniqKey="Gratten J" first="Jacob" last="Gratten">Jacob Gratten</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Lee, James J" sort="Lee, James J" uniqKey="Lee J" first="James J" last="Lee">James J. Lee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Jimmy Z" sort="Liu, Jimmy Z" uniqKey="Liu J" first="Jimmy Z" last="Liu">Jimmy Z. Liu</name><affiliation wicri:level="1"><nlm:affiliation>New York Genome Center, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New York Genome Center, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="De Vlaming, Ronald" sort="De Vlaming, Ronald" uniqKey="De Vlaming R" first="Ronald" last="De Vlaming">Ronald De Vlaming</name><affiliation wicri:level="1"><nlm:affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Ahluwalia, Tarunveer S" sort="Ahluwalia, Tarunveer S" uniqKey="Ahluwalia T" first="Tarunveer S" last="Ahluwalia">Tarunveer S. Ahluwalia</name><affiliation wicri:level="1"><nlm:affiliation>COPSAC (Copenhagen Prospective Studies on Asthma in Childhood), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>COPSAC (Copenhagen Prospective Studies on Asthma in Childhood), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Buchwald, Jadwiga" sort="Buchwald, Jadwiga" uniqKey="Buchwald J" first="Jadwiga" last="Buchwald">Jadwiga Buchwald</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Cavadino, Alana" sort="Cavadino, Alana" uniqKey="Cavadino A" first="Alana" last="Cavadino">Alana Cavadino</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Frazier Wood, Alexis C" sort="Frazier Wood, Alexis C" uniqKey="Frazier Wood A" first="Alexis C" last="Frazier-Wood">Alexis C. Frazier-Wood</name><affiliation wicri:level="1"><nlm:affiliation>USDA-ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>USDA-ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas</wicri:regionArea></affiliation></author><author><name sortKey="Furlotte, Nicholas A" sort="Furlotte, Nicholas A" uniqKey="Furlotte N" first="Nicholas A" last="Furlotte">Nicholas A. Furlotte</name><affiliation wicri:level="1"><nlm:affiliation>23andMe, Inc., Mountain View, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>23andMe, Inc., Mountain View, California</wicri:regionArea></affiliation></author><author><name sortKey="Garfield, Victoria" sort="Garfield, Victoria" uniqKey="Garfield V" first="Victoria" last="Garfield">Victoria Garfield</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Geisel, Marie Henrike" sort="Geisel, Marie Henrike" uniqKey="Geisel M" first="Marie Henrike" last="Geisel">Marie Henrike Geisel</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen</wicri:regionArea></affiliation></author><author><name sortKey="Gonzalez, Juan R" sort="Gonzalez, Juan R" uniqKey="Gonzalez J" first="Juan R" last="Gonzalez">Juan R. Gonzalez</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Research in Environmental Epidemiology, Institute for Global Health, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centre for Research in Environmental Epidemiology, Institute for Global Health, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Haitjema, Saskia" sort="Haitjema, Saskia" uniqKey="Haitjema S" first="Saskia" last="Haitjema">Saskia Haitjema</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Karlsson, Robert" sort="Karlsson, Robert" uniqKey="Karlsson R" first="Robert" last="Karlsson">Robert Karlsson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Laan, Sander W" sort="Van Der Laan, Sander W" uniqKey="Van Der Laan S" first="Sander W" last="Van Der Laan">Sander W. Van Der Laan</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Ladwig, Karl Heinz" sort="Ladwig, Karl Heinz" uniqKey="Ladwig K" first="Karl-Heinz" last="Ladwig">Karl-Heinz Ladwig</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universität München, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Lee, Sven J" sort="Van Der Lee, Sven J" uniqKey="Van Der Lee S" first="Sven J" last="Van Der Lee">Sven J. Van Der Lee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Lind, Penelope A" sort="Lind, Penelope A" uniqKey="Lind P" first="Penelope A" last="Lind">Penelope A. Lind</name><affiliation wicri:level="1"><nlm:affiliation>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Tian" sort="Liu, Tian" uniqKey="Liu T" first="Tian" last="Liu">Tian Liu</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Human Development, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Human Development, Berlin</wicri:regionArea></affiliation></author><author><name sortKey="Matteson, Lindsay" sort="Matteson, Lindsay" uniqKey="Matteson L" first="Lindsay" last="Matteson">Lindsay Matteson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Miller, Michael B" sort="Miller, Michael B" uniqKey="Miller M" first="Michael B" last="Miller">Michael B. Miller</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Minica, Camelia C" sort="Minica, Camelia C" uniqKey="Minica C" first="Camelia C" last="Minica">Camelia C. Minica</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Mook Kanamori, Dennis" sort="Mook Kanamori, Dennis" uniqKey="Mook Kanamori D" first="Dennis" last="Mook-Kanamori">Dennis Mook-Kanamori</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Clinical Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Most, Peter J" sort="Van Der Most, Peter J" uniqKey="Van Der Most P" first="Peter J" last="Van Der Most">Peter J. Van Der Most</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Oldmeadow, Christopher" sort="Oldmeadow, Christopher" uniqKey="Oldmeadow C" first="Christopher" last="Oldmeadow">Christopher Oldmeadow</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Qian, Yong" sort="Qian, Yong" uniqKey="Qian Y" first="Yong" last="Qian">Yong Qian</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Raitakari, Olli" sort="Raitakari, Olli" uniqKey="Raitakari O" first="Olli" last="Raitakari">Olli Raitakari</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Rawal, Rajesh" sort="Rawal, Rajesh" uniqKey="Rawal R" first="Rajesh" last="Rawal">Rajesh Rawal</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Realo, Anu" sort="Realo, Anu" uniqKey="Realo A" first="Anu" last="Realo">Anu Realo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Department of Psychology, University of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Rueedi, Rico" sort="Rueedi, Rico" uniqKey="Rueedi R" first="Rico" last="Rueedi">Rico Rueedi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Computational Biology, University of Lausanne, Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Borge" sort="Schmidt, Borge" uniqKey="Schmidt B" first="Börge" last="Schmidt">Börge Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen</wicri:regionArea></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea></affiliation></author><author><name sortKey="Stergiakouli, Evie" sort="Stergiakouli, Evie" uniqKey="Stergiakouli E" first="Evie" last="Stergiakouli">Evie Stergiakouli</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Taylor, Kent" sort="Taylor, Kent" uniqKey="Taylor K" first="Kent" last="Taylor">Kent Taylor</name><affiliation wicri:level="1"><nlm:affiliation>Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA, Torrence, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA, Torrence, California</wicri:regionArea></affiliation></author><author><name sortKey="Wedenoja, Juho" sort="Wedenoja, Juho" uniqKey="Wedenoja J" first="Juho" last="Wedenoja">Juho Wedenoja</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Wellmann, Juergen" sort="Wellmann, Juergen" uniqKey="Wellmann J" first="Juergen" last="Wellmann">Juergen Wellmann</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology and Social Medicine, University of Münster, Münster</wicri:regionArea></affiliation></author><author><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Willems, Sara M" sort="Willems, Sara M" uniqKey="Willems S" first="Sara M" last="Willems">Sara M. Willems</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Zhao, Wei" sort="Zhao, Wei" uniqKey="Zhao W" first="Wei" last="Zhao">Wei Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Bakshi, Andrew" sort="Bakshi, Andrew" uniqKey="Bakshi A" first="Andrew" last="Bakshi">Andrew Bakshi</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Boyle, Patricia A" sort="Boyle, Patricia A" uniqKey="Boyle P" first="Patricia A" last="Boyle">Patricia A. Boyle</name><affiliation wicri:level="1"><nlm:affiliation>Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Cherney, Samantha" sort="Cherney, Samantha" uniqKey="Cherney S" first="Samantha" last="Cherney">Samantha Cherney</name><affiliation wicri:level="1"><nlm:affiliation>RAND Corporation, Santa Monica, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>RAND Corporation, Santa Monica, California</wicri:regionArea></affiliation></author><author><name sortKey="Cox, Simon R" sort="Cox, Simon R" uniqKey="Cox S" first="Simon R" last="Cox">Simon R. Cox</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Davies, Gail" sort="Davies, Gail" uniqKey="Davies G" first="Gail" last="Davies">Gail Davies</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Davis, Oliver S P" sort="Davis, Oliver S P" uniqKey="Davis O" first="Oliver S P" last="Davis">Oliver S P. Davis</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Ding, Jun" sort="Ding, Jun" uniqKey="Ding J" first="Jun" last="Ding">Jun Ding</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Direk, Nese" sort="Direk, Nese" uniqKey="Direk N" first="Nese" last="Direk">Nese Direk</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Eibich, Peter" sort="Eibich, Peter" uniqKey="Eibich P" first="Peter" last="Eibich">Peter Eibich</name><affiliation wicri:level="1"><nlm:affiliation>German Socio-Economic Panel Study, DIW Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Socio-Economic Panel Study, DIW Berlin, Berlin</wicri:regionArea></affiliation></author><author><name sortKey="Emeny, Rebecca T" sort="Emeny, Rebecca T" uniqKey="Emeny R" first="Rebecca T" last="Emeny">Rebecca T. Emeny</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II, Mental Health Research Unit, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Mental Health Research Unit, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Fatemifar, Ghazaleh" sort="Fatemifar, Ghazaleh" uniqKey="Fatemifar G" first="Ghazaleh" last="Fatemifar">Ghazaleh Fatemifar</name><affiliation wicri:level="1"><nlm:affiliation>Farr Institute of Health Informatics, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Farr Institute of Health Informatics, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Faul, Jessica D" sort="Faul, Jessica D" uniqKey="Faul J" first="Jessica D" last="Faul">Jessica D. Faul</name><affiliation wicri:level="1"><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Forstner, Andreas" sort="Forstner, Andreas" uniqKey="Forstner A" first="Andreas" last="Forstner">Andreas Forstner</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Bonn, Bonn</wicri:regionArea></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg</wicri:regionArea></affiliation></author><author><name sortKey="Gupta, Richa" sort="Gupta, Richa" uniqKey="Gupta R" first="Richa" last="Gupta">Richa Gupta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Epidemiology, Demography, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology, Demography, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Harris, Juliette M" sort="Harris, Juliette M" uniqKey="Harris J" first="Juliette M" last="Harris">Juliette M. Harris</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Holliday, Elizabeth G" sort="Holliday, Elizabeth G" uniqKey="Holliday E" first="Elizabeth G" last="Holliday">Elizabeth G. Holliday</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><affiliation wicri:level="1"><nlm:affiliation>Program in Translational NeuroPsychiatric Genomics, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Translational NeuroPsychiatric Genomics, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Kaakinen, Marika A" sort="Kaakinen, Marika A" uniqKey="Kaakinen M" first="Marika A" last="Kaakinen">Marika A. Kaakinen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genomics of Common Disease, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genomics of Common Disease, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Kajantie, Eero" sort="Kajantie, Eero" uniqKey="Kajantie E" first="Eero" last="Kajantie">Eero Kajantie</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Pediatrics, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Karhunen, Ville" sort="Karhunen, Ville" uniqKey="Karhunen V" first="Ville" last="Karhunen">Ville Karhunen</name><affiliation wicri:level="1"><nlm:affiliation>Center for Life Course Health Research, University of Oulu and Oulu University Hospital, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Center for Life Course Health Research, University of Oulu and Oulu University Hospital, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Social and Economic Research, University of Essex, Wivenhoe Park, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Social and Economic Research, University of Essex, Wivenhoe Park</wicri:regionArea></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation wicri:level="1"><nlm:affiliation>Neuroepidemiology Section, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Neuroepidemiology Section, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Li Gao, Ruifang" sort="Li Gao, Ruifang" uniqKey="Li Gao R" first="Ruifang" last="Li-Gao">Ruifang Li-Gao</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Clinical Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Koini, Marisa" sort="Koini, Marisa" uniqKey="Koini M" first="Marisa" last="Koini">Marisa Koini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, General Hospital and Medical University Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Loukola, Anu" sort="Loukola, Anu" uniqKey="Loukola A" first="Anu" last="Loukola">Anu Loukola</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Marques Vidal, Pedro" sort="Marques Vidal, Pedro" uniqKey="Marques Vidal P" first="Pedro" last="Marques-Vidal">Pedro Marques-Vidal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Mosing, Miriam A" sort="Mosing, Miriam A" uniqKey="Mosing M" first="Miriam A" last="Mosing">Miriam A. Mosing</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Pattie, Alison" sort="Pattie, Alison" uniqKey="Pattie A" first="Alison" last="Pattie">Alison Pattie</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Petrovic, Katja E" sort="Petrovic, Katja E" uniqKey="Petrovic K" first="Katja E" last="Petrovic">Katja E. Petrovic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, General Hospital and Medical University Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Pulkki R Back, Laura" sort="Pulkki R Back, Laura" uniqKey="Pulkki R Back L" first="Laura" last="Pulkki-R Back">Laura Pulkki-R Back</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Quaye, Lydia" sort="Quaye, Lydia" uniqKey="Quaye L" first="Lydia" last="Quaye">Lydia Quaye</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="R Ikkonen, Katri" sort="R Ikkonen, Katri" uniqKey="R Ikkonen K" first="Katri" last="R Ikkönen">Katri R Ikkönen</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Scott, Rodney J" sort="Scott, Rodney J" uniqKey="Scott R" first="Rodney J" last="Scott">Rodney J. Scott</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Smith, Jennifer A" sort="Smith, Jennifer A" uniqKey="Smith J" first="Jennifer A" last="Smith">Jennifer A. Smith</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Sutin, Angelina R" sort="Sutin, Angelina R" uniqKey="Sutin A" first="Angelina R" last="Sutin">Angelina R. Sutin</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Trzaskowski, Maciej" sort="Trzaskowski, Maciej" uniqKey="Trzaskowski M" first="Maciej" last="Trzaskowski">Maciej Trzaskowski</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Vinkhuyzen, Anna E" sort="Vinkhuyzen, Anna E" uniqKey="Vinkhuyzen A" first="Anna E" last="Vinkhuyzen">Anna E. Vinkhuyzen</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Attia, John R" sort="Attia, John R" uniqKey="Attia J" first="John R" last="Attia">John R. Attia</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales</wicri:regionArea></affiliation></author><author><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea></affiliation></author><author><name sortKey="Berger, Klaus" sort="Berger, Klaus" uniqKey="Berger K" first="Klaus" last="Berger">Klaus Berger</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology and Social Medicine, University of Münster, Münster</wicri:regionArea></affiliation></author><author><name sortKey="Bertram, Lars" sort="Bertram, Lars" uniqKey="Bertram L" first="Lars" last="Bertram">Lars Bertram</name><affiliation wicri:level="1"><nlm:affiliation>Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institute of Neurogenetics and Institute of Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institute of Neurogenetics and Institute of Integrative and Experimental Genomics, University of Lübeck, Lübeck</wicri:regionArea></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Chang, Shun Chiao" sort="Chang, Shun Chiao" uniqKey="Chang S" first="Shun-Chiao" last="Chang">Shun-Chiao Chang</name><affiliation wicri:level="1"><nlm:affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Cucca, Francesco" sort="Cucca, Francesco" uniqKey="Cucca F" first="Francesco" last="Cucca">Francesco Cucca</name><affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cittadella Universitarià di Monserrato, Monserrato, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cittadella Universitarià di Monserrato, Monserrato</wicri:regionArea></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><affiliation wicri:level="1"><nlm:affiliation>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Bultmann, Ute" sort="Bultmann, Ute" uniqKey="Bultmann U" first="Ute" last="Bültmann">Ute Bültmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Groenen, Patrick J F" sort="Groenen, Patrick J F" uniqKey="Groenen P" first="Patrick J F" last="Groenen">Patrick J F. Groenen</name><affiliation wicri:level="1"><nlm:affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea></affiliation></author><author><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Hartman, Catharine A" sort="Hartman, Catharine A" uniqKey="Hartman C" first="Catharine A" last="Hartman">Catharine A. Hartman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="Haworth, Claire M A" sort="Haworth, Claire M A" uniqKey="Haworth C" first="Claire M A" last="Haworth">Claire M A. Haworth</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="1"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea></affiliation></author><author><name sortKey="Heath, Andrew C" sort="Heath, Andrew C" uniqKey="Heath A" first="Andrew C" last="Heath">Andrew C. Heath</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea></affiliation></author><author><name sortKey="Hinds, David A" sort="Hinds, David A" uniqKey="Hinds D" first="David A" last="Hinds">David A. Hinds</name><affiliation wicri:level="1"><nlm:affiliation>23andMe, Inc., Mountain View, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>23andMe, Inc., Mountain View, California</wicri:regionArea></affiliation></author><author><name sortKey="Hypponen, Elina" sort="Hypponen, Elina" uniqKey="Hypponen E" first="Elina" last="Hyppönen">Elina Hyppönen</name><affiliation wicri:level="1"><nlm:affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>South Australian Health and Medical Research Institute, Adelaide, South Australia</wicri:regionArea></affiliation></author><author><name sortKey="Iacono, William G" sort="Iacono, William G" uniqKey="Iacono W" first="William G" last="Iacono">William G. Iacono</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genomics of Common Disease, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genomics of Common Disease, Imperial College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen</wicri:regionArea></affiliation></author><author><name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L R" last="Kardia">Sharon L R. Kardia</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Keltikangas J Rvinen, Liisa" sort="Keltikangas J Rvinen, Liisa" uniqKey="Keltikangas J Rvinen L" first="Liisa" last="Keltikangas-J Rvinen">Liisa Keltikangas-J Rvinen</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Kubzansky, Laura D" sort="Kubzansky, Laura D" uniqKey="Kubzansky L" first="Laura D" last="Kubzansky">Laura D. Kubzansky</name><affiliation wicri:level="1"><nlm:affiliation>Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:affiliation>Fimlab Laboratories, Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Fimlab Laboratories, Tampere</wicri:regionArea></affiliation></author><author><name sortKey="Magnusson, Patrik K E" sort="Magnusson, Patrik K E" uniqKey="Magnusson P" first="Patrik K E" last="Magnusson">Patrik K E. Magnusson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Mcgue, Matt" sort="Mcgue, Matt" uniqKey="Mcgue M" first="Matt" last="Mcgue">Matt Mcgue</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Mills, Melinda" sort="Mills, Melinda" uniqKey="Mills M" first="Melinda" last="Mills">Melinda Mills</name><affiliation wicri:level="1"><nlm:affiliation>Department of Sociology, University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Sociology, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="De Mutsert, Renee" sort="De Mutsert, Renee" uniqKey="De Mutsert R" first="Renée" last="De Mutsert">Renée De Mutsert</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Clinical Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J" last="Oldehinkel">Albertine J. Oldehinkel</name><affiliation wicri:level="1"><nlm:affiliation>Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Pasterkamp, Gerard" sort="Pasterkamp, Gerard" uniqKey="Pasterkamp G" first="Gerard" last="Pasterkamp">Gerard Pasterkamp</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L" last="Pedersen">Nancy L. Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Plomin, Robert" sort="Plomin, Robert" uniqKey="Plomin R" first="Robert" last="Plomin">Robert Plomin</name><affiliation wicri:level="1"><nlm:affiliation>Social, Genetic and Developmental Psychiatry Centre, King's College London, De Crespigny Park, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic and Developmental Psychiatry Centre, King's College London, De Crespigny Park</wicri:regionArea></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split</wicri:regionArea></affiliation></author><author><name sortKey="Power, Christine" sort="Power, Christine" uniqKey="Power C" first="Christine" last="Power">Christine Power</name><affiliation wicri:level="1"><nlm:affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>South Australian Health and Medical Research Institute, Adelaide, South Australia</wicri:regionArea></affiliation></author><author><name sortKey="Rich, Stephen S" sort="Rich, Stephen S" uniqKey="Rich S" first="Stephen S" last="Rich">Stephen S. Rich</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia</wicri:regionArea></affiliation></author><author><name sortKey="Rosendaal, Frits R" sort="Rosendaal, Frits R" uniqKey="Rosendaal F" first="Frits R" last="Rosendaal">Frits R. Rosendaal</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Clinical Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Den Ruijter, Hester M" sort="Den Ruijter, Hester M" uniqKey="Den Ruijter H" first="Hester M" last="Den Ruijter">Hester M. Den Ruijter</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Schlessinger, David" sort="Schlessinger, David" uniqKey="Schlessinger D" first="David" last="Schlessinger">David Schlessinger</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, General Hospital and Medical University Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Svento, Rauli" sort="Svento, Rauli" uniqKey="Svento R" first="Rauli" last="Svento">Rauli Svento</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Oulu Business School, Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Economics, Oulu Business School, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, General Hospital and Medical University Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Alizadeh, Behrooz Z" sort="Alizadeh, Behrooz Z" uniqKey="Alizadeh B" first="Behrooz Z" last="Alizadeh">Behrooz Z. Alizadeh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea></affiliation></author><author><name sortKey="S Rensen, Thorkild I A" sort="S Rensen, Thorkild I A" uniqKey="S Rensen T" first="Thorkild I A" last="S Rensen">Thorkild I A. S Rensen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Steptoe, Andrew" sort="Steptoe, Andrew" uniqKey="Steptoe A" first="Andrew" last="Steptoe">Andrew Steptoe</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Terracciano, Antonio" sort="Terracciano, Antonio" uniqKey="Terracciano A" first="Antonio" last="Terracciano">Antonio Terracciano</name><affiliation wicri:level="1"><nlm:affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland</wicri:regionArea></affiliation></author><author><name sortKey="Thurik, A Roy" sort="Thurik, A Roy" uniqKey="Thurik A" first="A Roy" last="Thurik">A Roy Thurik</name><affiliation wicri:level="1"><nlm:affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Timpson, Nicholas J" sort="Timpson, Nicholas J" uniqKey="Timpson N" first="Nicholas J" last="Timpson">Nicholas J. Timpson</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Tiemeier, Henning" sort="Tiemeier, Henning" uniqKey="Tiemeier H" first="Henning" last="Tiemeier">Henning Tiemeier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne</wicri:regionArea></affiliation></author><author><name sortKey="Wagner, Gert G" sort="Wagner, Gert G" uniqKey="Wagner G" first="Gert G" last="Wagner">Gert G. Wagner</name><affiliation wicri:level="1"><nlm:affiliation>Max Planck Institute for Human Development, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Human Development, Berlin</wicri:regionArea></affiliation></author><author><name sortKey="Weir, David R" sort="Weir, David R" uniqKey="Weir D" first="David R" last="Weir">David R. Weir</name><affiliation wicri:level="1"><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Jian" sort="Yang, Jian" uniqKey="Yang J" first="Jian" last="Yang">Jian Yang</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Conley, Dalton C" sort="Conley, Dalton C" uniqKey="Conley D" first="Dalton C" last="Conley">Dalton C. Conley</name><affiliation wicri:level="1"><nlm:affiliation>Department of Sociology, Princeton University, Princeton, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Sociology, Princeton University, Princeton, New Jersey</wicri:regionArea></affiliation></author><author><name sortKey="Smith, George Davey" sort="Smith, George Davey" uniqKey="Smith G" first="George Davey" last="Smith">George Davey Smith</name><affiliation wicri:level="1"><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Integrative Epidemiology Unit, University of Bristol, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Johannesson, Magnus" sort="Johannesson, Magnus" uniqKey="Johannesson M" first="Magnus" last="Johannesson">Magnus Johannesson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Stockholm School of Economics, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Economics, Stockholm School of Economics, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Laibson, David I" sort="Laibson, David I" uniqKey="Laibson D" first="David I" last="Laibson">David I. Laibson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Harvard University, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Economics, Harvard University, Cambridge, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Medland, Sarah E" sort="Medland, Sarah E" uniqKey="Medland S" first="Sarah E" last="Medland">Sarah E. Medland</name><affiliation wicri:level="1"><nlm:affiliation>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea></affiliation></author><author><name sortKey="Meyer, Michelle N" sort="Meyer, Michelle N" uniqKey="Meyer M" first="Michelle N" last="Meyer">Michelle N. Meyer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Bioethics, Clarkson University, Schenectady, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Bioethics, Clarkson University, Schenectady, New York</wicri:regionArea></affiliation></author><author><name sortKey="Pickrell, Joseph K" sort="Pickrell, Joseph K" uniqKey="Pickrell J" first="Joseph K" last="Pickrell">Joseph K. Pickrell</name><affiliation wicri:level="1"><nlm:affiliation>New York Genome Center, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New York Genome Center, New York, New York</wicri:regionArea></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea></affiliation></author><author><name sortKey="Krueger, Robert F" sort="Krueger, Robert F" uniqKey="Krueger R" first="Robert F" last="Krueger">Robert F. Krueger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota</wicri:regionArea></affiliation></author><author><name sortKey="Beauchamp, Jonathan P" sort="Beauchamp, Jonathan P" uniqKey="Beauchamp J" first="Jonathan P" last="Beauchamp">Jonathan P. Beauchamp</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, Harvard University, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Economics, Harvard University, Cambridge, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Koellinger, Philipp D" sort="Koellinger, Philipp D" uniqKey="Koellinger P" first="Philipp D" last="Koellinger">Philipp D. Koellinger</name><affiliation wicri:level="1"><nlm:affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Benjamin, Daniel J" sort="Benjamin, Daniel J" uniqKey="Benjamin D" first="Daniel J" last="Benjamin">Daniel J. Benjamin</name><affiliation wicri:level="1"><nlm:affiliation>Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Economic and Social Research, University of Southern California, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Bartels, Meike" sort="Bartels, Meike" uniqKey="Bartels M" first="Meike" last="Bartels">Meike Bartels</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, Vrije Universiteit, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Cesarini, David" sort="Cesarini, David" uniqKey="Cesarini D" first="David" last="Cesarini">David Cesarini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics, New York University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Economics, New York University, New York, New York</wicri:regionArea></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="eISSN">1546-1718</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anxiety Disorders (genetics)</term><term>Bayes Theorem</term><term>Depression (genetics)</term><term>Genome-Wide Association Study</term><term>Humans</term><term>Phenotype</term><term>Polymorphism, Single Nucleotide</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Dépression (génétique)</term><term>Humains</term><term>Phénotype</term><term>Polymorphisme de nucléotide simple</term><term>Théorème de Bayes</term><term>Troubles anxieux (génétique)</term><term>Étude d'association pangénomique</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Anxiety Disorders</term><term>Depression</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Dépression</term><term>Troubles anxieux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Bayes Theorem</term><term>Genome-Wide Association Study</term><term>Humans</term><term>Phenotype</term><term>Polymorphism, Single Nucleotide</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Phénotype</term><term>Polymorphisme de nucléotide simple</term><term>Théorème de Bayes</term><term>Étude d'association pangénomique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Very few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies. Subjective well-being, a phenotype that is genetically correlated with both of these traits, has not yet been studied with genome-wide data. We conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n = 161,460), and neuroticism (n = 170,911). We identify 3 variants associated with subjective well-being, 2 variants associated with depressive symptoms, and 11 variants associated with neuroticism, including 2 inversion polymorphisms. The two loci associated with depressive symptoms replicate in an independent depression sample. Joint analyses that exploit the high genetic correlations between the phenotypes (|ρ^| ≈ 0.8) strengthen the overall credibility of the findings and allow us to identify additional variants. Across our phenotypes, loci regulating expression in central nervous system and adrenal or pancreas tissues are strongly enriched for association.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27089181</PMID><DateCreated><Year>2016</Year><Month>05</Month><Day>27</Day></DateCreated><DateCompleted><Year>2017</Year><Month>06</Month><Day>28</Day></DateCompleted><DateRevised><Year>2017</Year><Month>11</Month><Day>16</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1546-1718</ISSN><JournalIssue CitedMedium="Internet"><Volume>48</Volume><Issue>6</Issue><PubDate><Year>2016</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Nature genetics</Title><ISOAbbreviation>Nat. Genet.</ISOAbbreviation></Journal><ArticleTitle>Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.</ArticleTitle><Pagination><MedlinePgn>624-33</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/ng.3552</ELocationID><Abstract><AbstractText>Very few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies. Subjective well-being, a phenotype that is genetically correlated with both of these traits, has not yet been studied with genome-wide data. We conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n = 161,460), and neuroticism (n = 170,911). We identify 3 variants associated with subjective well-being, 2 variants associated with depressive symptoms, and 11 variants associated with neuroticism, including 2 inversion polymorphisms. The two loci associated with depressive symptoms replicate in an independent depression sample. Joint analyses that exploit the high genetic correlations between the phenotypes (|ρ^| ≈ 0.8) strengthen the overall credibility of the findings and allow us to identify additional variants. Across our phenotypes, loci regulating expression in central nervous system and adrenal or pancreas tissues are strongly enriched for association.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Okbay</LastName><ForeName>Aysu</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baselmans</LastName><ForeName>Bart M L</ForeName><Initials>BM</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Neve</LastName><ForeName>Jan-Emmanuel</ForeName><Initials>JE</Initials><AffiliationInfo><Affiliation>Saïd Business School, University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Turley</LastName><ForeName>Patrick</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Economics, Harvard University, Cambridge, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nivard</LastName><ForeName>Michel G</ForeName><Initials>MG</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-2015-1888</Identifier><AffiliationInfo><Affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fontana</LastName><ForeName>Mark Alan</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meddens</LastName><ForeName>S Fleur W</ForeName><Initials>SF</Initials><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Complex Trait Genetics, Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Amsterdam Business School, University of Amsterdam, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Linnér</LastName><ForeName>Richard Karlsson</ForeName><Initials>RK</Initials><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Complex Trait Genetics, Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Amsterdam Business School, University of Amsterdam, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rietveld</LastName><ForeName>Cornelius A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Derringer</LastName><ForeName>Jaime</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Illinois, Champaign, Illinois, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gratten</LastName><ForeName>Jacob</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>James J</ForeName><Initials>JJ</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-6547-5128</Identifier><AffiliationInfo><Affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Jimmy Z</ForeName><Initials>JZ</Initials><AffiliationInfo><Affiliation>New York Genome Center, New York, New York, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Vlaming</LastName><ForeName>Ronald</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ahluwalia</LastName><ForeName>Tarunveer S</ForeName><Initials>TS</Initials><AffiliationInfo><Affiliation>COPSAC (Copenhagen Prospective Studies on Asthma in Childhood), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Steno Diabetes Center, Gentofte, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buchwald</LastName><ForeName>Jadwiga</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cavadino</LastName><ForeName>Alana</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Frazier-Wood</LastName><ForeName>Alexis C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>USDA-ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Furlotte</LastName><ForeName>Nicholas A</ForeName><Initials>NA</Initials><AffiliationInfo><Affiliation>23andMe, Inc., Mountain View, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Garfield</LastName><ForeName>Victoria</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Public Health, University College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Geisel</LastName><ForeName>Marie Henrike</ForeName><Initials>MH</Initials><AffiliationInfo><Affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gonzalez</LastName><ForeName>Juan R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Centre for Research in Environmental Epidemiology, Institute for Global Health, Barcelona, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Universitat Pompeu Fabra, Barcelona, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>CIBER Epidemiología y Salud Pública, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haitjema</LastName><ForeName>Saskia</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karlsson</LastName><ForeName>Robert</ForeName><Initials>R</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-8949-2587</Identifier><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Laan</LastName><ForeName>Sander W</ForeName><Initials>SW</Initials><AffiliationInfo><Affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ladwig</LastName><ForeName>Karl-Heinz</ForeName><Initials>KH</Initials><AffiliationInfo><Affiliation>Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lahti</LastName><ForeName>Jari</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Folkhälsan Research Centre, Helsingfors, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Lee</LastName><ForeName>Sven J</ForeName><Initials>SJ</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-1606-8643</Identifier><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lind</LastName><ForeName>Penelope A</ForeName><Initials>PA</Initials><AffiliationInfo><Affiliation>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Tian</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Human Development, Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Matteson</LastName><ForeName>Lindsay</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mihailov</LastName><ForeName>Evelin</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Miller</LastName><ForeName>Michael B</ForeName><Initials>MB</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Minica</LastName><ForeName>Camelia C</ForeName><Initials>CC</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nolte</LastName><ForeName>Ilja M</ForeName><Initials>IM</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mook-Kanamori</LastName><ForeName>Dennis</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>BESC, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Most</LastName><ForeName>Peter J</ForeName><Initials>PJ</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-8450-3518</Identifier><AffiliationInfo><Affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oldmeadow</LastName><ForeName>Christopher</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qian</LastName><ForeName>Yong</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raitakari</LastName><ForeName>Olli</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Clinical Physiology, Turku University Hospital, Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rawal</LastName><ForeName>Rajesh</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Realo</LastName><ForeName>Anu</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, University of Warwick, Coventry, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rueedi</LastName><ForeName>Rico</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Swiss Institute of Bioinformatics, Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Börge</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>Albert V</ForeName><Initials>AV</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-1942-5845</Identifier><AffiliationInfo><Affiliation>Icelandic Heart Association, Kopavogur, Iceland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stergiakouli</LastName><ForeName>Evie</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tanaka</LastName><ForeName>Toshiko</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Taylor</LastName><ForeName>Kent</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA, Torrence, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wedenoja</LastName><ForeName>Juho</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wellmann</LastName><ForeName>Juergen</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Westra</LastName><ForeName>Harm-Jan</ForeName><Initials>HJ</Initials><AffiliationInfo><Affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Rheumatology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Willems</LastName><ForeName>Sara M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Wei</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>LifeLines Cohort Study</CollectiveName></Author><Author ValidYN="Y"><LastName>Amin</LastName><ForeName>Najaf</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bakshi</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boyle</LastName><ForeName>Patricia A</ForeName><Initials>PA</Initials><AffiliationInfo><Affiliation>Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cherney</LastName><ForeName>Samantha</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>RAND Corporation, Santa Monica, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cox</LastName><ForeName>Simon R</ForeName><Initials>SR</Initials><AffiliationInfo><Affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davies</LastName><ForeName>Gail</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davis</LastName><ForeName>Oliver S P</ForeName><Initials>OS</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ding</LastName><ForeName>Jun</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Direk</LastName><ForeName>Nese</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eibich</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>German Socio-Economic Panel Study, DIW Berlin, Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Emeny</LastName><ForeName>Rebecca T</ForeName><Initials>RT</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology II, Mental Health Research Unit, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fatemifar</LastName><ForeName>Ghazaleh</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Farr Institute of Health Informatics, University College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Faul</LastName><ForeName>Jessica D</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferrucci</LastName><ForeName>Luigi</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Forstner</LastName><ForeName>Andreas</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, University of Bonn, Bonn, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gieger</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gupta</LastName><ForeName>Richa</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harris</LastName><ForeName>Tamara B</ForeName><Initials>TB</Initials><AffiliationInfo><Affiliation>Laboratory of Epidemiology, Demography, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harris</LastName><ForeName>Juliette M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Holliday</LastName><ForeName>Elizabeth G</ForeName><Initials>EG</Initials><AffiliationInfo><Affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hottenga</LastName><ForeName>Jouke-Jan</ForeName><Initials>JJ</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Jager</LastName><ForeName>Philip L</ForeName><Initials>PL</Initials><AffiliationInfo><Affiliation>Program in Translational NeuroPsychiatric Genomics, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Harvard Medical School, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaakinen</LastName><ForeName>Marika A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Department of Genomics of Common Disease, Imperial College London, London, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Center for Life Course Health Research, University of Oulu and Oulu University Hospital, Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kajantie</LastName><ForeName>Eero</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Institute for Health and Welfare, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karhunen</LastName><ForeName>Ville</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Center for Life Course Health Research, University of Oulu and Oulu University Hospital, Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kolcic</LastName><ForeName>Ivana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kumari</LastName><ForeName>Meena</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute for Social and Economic Research, University of Essex, Wivenhoe Park, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Launer</LastName><ForeName>Lenore J</ForeName><Initials>LJ</Initials><AffiliationInfo><Affiliation>Neuroepidemiology Section, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Franke</LastName><ForeName>Lude</ForeName><Initials>L</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-5159-8802</Identifier><AffiliationInfo><Affiliation>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li-Gao</LastName><ForeName>Ruifang</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koini</LastName><ForeName>Marisa</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Loukola</LastName><ForeName>Anu</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marques-Vidal</LastName><ForeName>Pedro</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Montgomery</LastName><ForeName>Grant W</ForeName><Initials>GW</Initials><AffiliationInfo><Affiliation>Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mosing</LastName><ForeName>Miriam A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Paternoster</LastName><ForeName>Lavinia</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pattie</LastName><ForeName>Alison</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Petrovic</LastName><ForeName>Katja E</ForeName><Initials>KE</Initials><AffiliationInfo><Affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pulkki-Råback</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Quaye</LastName><ForeName>Lydia</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Räikkönen</LastName><ForeName>Katri</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudan</LastName><ForeName>Igor</ForeName><Initials>I</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-6993-6884</Identifier><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scott</LastName><ForeName>Rodney J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Information-Based Medicine Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>Jennifer A</ForeName><Initials>JA</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-3575-5468</Identifier><AffiliationInfo><Affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sutin</LastName><ForeName>Angelina R</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, Florida, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Trzaskowski</LastName><ForeName>Maciej</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vinkhuyzen</LastName><ForeName>Anna E</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yu</LastName><ForeName>Lei</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zabaneh</LastName><ForeName>Delilah</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Attia</LastName><ForeName>John R</ForeName><Initials>JR</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-9800-1308</Identifier><AffiliationInfo><Affiliation>Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bennett</LastName><ForeName>David A</ForeName><Initials>DA</Initials><AffiliationInfo><Affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Berger</LastName><ForeName>Klaus</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bertram</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institute of Neurogenetics and Institute of Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Neuroepidemiology and Ageing Research Unit, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boomsma</LastName><ForeName>Dorret I</ForeName><Initials>DI</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Neuroscience Campus Amsterdam, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Snieder</LastName><ForeName>Harold</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chang</LastName><ForeName>Shun-Chiao</ForeName><Initials>SC</Initials><AffiliationInfo><Affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cucca</LastName><ForeName>Francesco</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cittadella Universitarià di Monserrato, Monserrato, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Deary</LastName><ForeName>Ian J</ForeName><Initials>IJ</Initials><AffiliationInfo><Affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Duijn</LastName><ForeName>Cornelia M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eriksson</LastName><ForeName>Johan G</ForeName><Initials>JG</Initials><AffiliationInfo><Affiliation>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Unit of General Practice, University Central Hospital, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bültmann</LastName><ForeName>Ute</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Geus</LastName><ForeName>Eco J C</ForeName><Initials>EJ</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-6022-2666</Identifier><AffiliationInfo><Affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Neuroscience Campus Amsterdam, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Groenen</LastName><ForeName>Patrick J F</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gudnason</LastName><ForeName>Vilmundur</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Kopavogur, Iceland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hansen</LastName><ForeName>Torben</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hartman</LastName><ForeName>Catharine A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haworth</LastName><ForeName>Claire M A</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hayward</LastName><ForeName>Caroline</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heath</LastName><ForeName>Andrew C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hinds</LastName><ForeName>David A</ForeName><Initials>DA</Initials><AffiliationInfo><Affiliation>23andMe, Inc., Mountain View, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hyppönen</LastName><ForeName>Elina</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Population Health Research, School of Health Sciences and Sansom Institute, University of South Australia, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Population, Policy and Practice, UCL Institute of Child Health, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Iacono</LastName><ForeName>William G</ForeName><Initials>WG</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Järvelin</LastName><ForeName>Marjo-Riitta</ForeName><Initials>MR</Initials><AffiliationInfo><Affiliation>Department of Genomics of Common Disease, Imperial College London, London, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Biocenter Oulu, University of Oulu, Oulu, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Unit of Primary Care, Oulu University Hospital, Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jöckel</LastName><ForeName>Karl-Heinz</ForeName><Initials>KH</Initials><AffiliationInfo><Affiliation>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaprio</LastName><ForeName>Jaakko</ForeName><Initials>J</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-3716-2455</Identifier><AffiliationInfo><Affiliation>Department of Public Health, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department for Health, THL (National Institute for Health and Welfare), Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kardia</LastName><ForeName>Sharon L R</ForeName><Initials>SL</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keltikangas-Järvinen</LastName><ForeName>Liisa</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kraft</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kubzansky</LastName><ForeName>Laura D</ForeName><Initials>LD</Initials><AffiliationInfo><Affiliation>Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lehtimäki</LastName><ForeName>Terho</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Fimlab Laboratories, Tampere, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Clinical Chemistry, University of Tampere, School of Medicine, Tampere, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Magnusson</LastName><ForeName>Patrik K E</ForeName><Initials>PK</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martin</LastName><ForeName>Nicholas G</ForeName><Initials>NG</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McGue</LastName><ForeName>Matt</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Metspalu</LastName><ForeName>Andres</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mills</LastName><ForeName>Melinda</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Sociology, University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Mutsert</LastName><ForeName>Renée</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oldehinkel</LastName><ForeName>Albertine J</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pasterkamp</LastName><ForeName>Gerard</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratory of Clinical Chemistry and Hematology, Division of Laboratories and Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pedersen</LastName><ForeName>Nancy L</ForeName><Initials>NL</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Plomin</LastName><ForeName>Robert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Social, Genetic and Developmental Psychiatry Centre, King's College London, De Crespigny Park, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Polasek</LastName><ForeName>Ozren</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Power</LastName><ForeName>Christine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Population, Policy and Practice, UCL Institute of Child Health, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rich</LastName><ForeName>Stephen S</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rosendaal</LastName><ForeName>Frits R</ForeName><Initials>FR</Initials><AffiliationInfo><Affiliation>Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>den Ruijter</LastName><ForeName>Hester M</ForeName><Initials>HM</Initials><AffiliationInfo><Affiliation>Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schlessinger</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Helena</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Unit for Genetic Epidemiology, Institute of Molecular Biology and Biochemistry, Center of Molecular Medicine, General Hospital and Medical University Graz, Graz, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Svento</LastName><ForeName>Rauli</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Economics, Oulu Business School, Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Reinhold</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alizadeh</LastName><ForeName>Behrooz Z</ForeName><Initials>BZ</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-1415-8007</Identifier><AffiliationInfo><Affiliation>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sørensen</LastName><ForeName>Thorkild I A</ForeName><Initials>TI</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals, Capital Region, Frederiksberg, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spector</LastName><ForeName>Tim D</ForeName><Initials>TD</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steptoe</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Public Health, University College London, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Terracciano</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, Florida, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thurik</LastName><ForeName>A Roy</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Montpellier Business School, Montpellier, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Panteia, Zoetermeer, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Timpson</LastName><ForeName>Nicholas J</ForeName><Initials>NJ</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tiemeier</LastName><ForeName>Henning</ForeName><Initials>H</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-4395-1397</Identifier><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Uitterlinden</LastName><ForeName>André G</ForeName><Initials>AG</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vollenweider</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wagner</LastName><ForeName>Gert G</ForeName><Initials>GG</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Human Development, Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Socio-Economic Panel Study, DIW Berlin, Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>School of Economics and Management, Berlin University of Technology, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weir</LastName><ForeName>David R</ForeName><Initials>DR</Initials><AffiliationInfo><Affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Jian</ForeName><Initials>J</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-2001-2474</Identifier><AffiliationInfo><Affiliation>Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Conley</LastName><ForeName>Dalton C</ForeName><Initials>DC</Initials><AffiliationInfo><Affiliation>Department of Sociology, Princeton University, Princeton, New Jersey, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>George Davey</ForeName><Initials>GD</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hofman</LastName><ForeName>Albert</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johannesson</LastName><ForeName>Magnus</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Economics, Stockholm School of Economics, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Laibson</LastName><ForeName>David I</ForeName><Initials>DI</Initials><AffiliationInfo><Affiliation>Department of Economics, Harvard University, Cambridge, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Medland</LastName><ForeName>Sarah E</ForeName><Initials>SE</Initials><AffiliationInfo><Affiliation>Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meyer</LastName><ForeName>Michelle N</ForeName><Initials>MN</Initials><AffiliationInfo><Affiliation>Department of Bioethics, Clarkson University, Schenectady, New York, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Icahn School of Medicine at Mount Sinai, New York, New York, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pickrell</LastName><ForeName>Joseph K</ForeName><Initials>JK</Initials><AffiliationInfo><Affiliation>New York Genome Center, New York, New York, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biological Sciences, Columbia University, New York, New York, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Esko</LastName><ForeName>Tõnu</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, University of Tartu, Tartu, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Krueger</LastName><ForeName>Robert F</ForeName><Initials>RF</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beauchamp</LastName><ForeName>Jonathan P</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Department of Economics, Harvard University, Cambridge, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koellinger</LastName><ForeName>Philipp D</ForeName><Initials>PD</Initials><AffiliationInfo><Affiliation>Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Complex Trait Genetics, Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Amsterdam Business School, University of Amsterdam, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benjamin</LastName><ForeName>Daniel J</ForeName><Initials>DJ</Initials><AffiliationInfo><Affiliation>Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bartels</LastName><ForeName>Meike</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Neuroscience Campus Amsterdam, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cesarini</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Economics, New York University, New York, New York, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Institute for Industrial Economics, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01 DA036216</GrantID><Acronym>DA</Acronym><Agency>NIDA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>G1001799</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>RF1 AG015819</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_UU_12013/3</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 AG017917</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MR/J012165/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R03 AG051960</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>UL1 TR000124</GrantID><Acronym>TR</Acronym><Agency>NCATS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MR/N01104X/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 DK063491</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_PC_15018</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 AG010161</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_UU_12013/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MC_PC_U127561128</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P01 AG005842</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R37 DA005147</GrantID><Acronym>DA</Acronym><Agency>NIDA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P30 AG012810</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 AG042568</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>T32 AG000186</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>647648</GrantID><Agency>European Research Council</Agency><Country>International</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>04</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Nat 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UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010641" MajorTopicYN="N">Phenotype</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020641" MajorTopicYN="Y">Polymorphism, Single Nucleotide</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">NIHMS772727 [Available on 10/18/16]</OtherID><OtherID Source="NLM">PMC4884152 [Available on 10/18/16]</OtherID><CoiStatement>Competing Financial Interests: The authors declare no competing financial interests.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>12</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>03</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>4</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>4</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>6</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27089181</ArticleId><ArticleId IdType="pii">ng.3552</ArticleId><ArticleId IdType="doi">10.1038/ng.3552</ArticleId><ArticleId IdType="pmc">PMC4884152</ArticleId><ArticleId IdType="mid">NIHMS772727</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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