Brain health: time matters in multiple sclerosis.
Identifieur interne : 001920 ( PubMed/Curation ); précédent : 001919; suivant : 001921Brain health: time matters in multiple sclerosis.
Auteurs : Gavin Giovannoni [Royaume-Uni] ; Helmut Butzkueven [Australie] ; Suhayl Dhib-Jalbut [États-Unis] ; Jeremy Hobart [Royaume-Uni] ; Gisela Kobelt [France] ; George Pepper [Royaume-Uni] ; Maria Pia Sormani [Italie] ; Christoph Thalheim [Belgique] ; Anthony Traboulsee [Canada] ; Timothy Vollmer [États-Unis]Source :
- Multiple sclerosis and related disorders [ 2211-0356 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Sclérose en plaques.
- physiopathologie : Encéphale, Sclérose en plaques.
- économie : Sclérose en plaques.
- Facteurs temps, Humains, Sclérose en plaques.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Multiple Sclerosis.
- economics : Multiple Sclerosis.
- physiopathology : Brain, Multiple Sclerosis.
- therapy : Multiple Sclerosis.
- Humans, Time Factors.
Abstract
We present international consensus recommendations for improving diagnosis, management and treatment access in multiple sclerosis (MS). Our vision is that these will be used widely among those committed to creating a better future for people with MS and their families.
DOI: 10.1016/j.msard.2016.07.003
PubMed: 27640924
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Electronic address: t.traboulsee@ubc.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine, University of British Columbia, Vancouver, BC</wicri:regionArea></affiliation></author><author><name sortKey="Vollmer, Timothy" sort="Vollmer, Timothy" uniqKey="Vollmer T" first="Timothy" last="Vollmer">Timothy Vollmer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Colorado Denver, Aurora, CO, USA. Electronic address: Timothy.Vollmer@ucdenver.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of Colorado Denver, Aurora, CO</wicri:regionArea></affiliation></author></analytic><series><title level="j">Multiple sclerosis and related disorders</title><idno type="eISSN">2211-0356</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brain (physiopathology)</term><term>Humans</term><term>Multiple Sclerosis (diagnosis)</term><term>Multiple Sclerosis (economics)</term><term>Multiple Sclerosis (physiopathology)</term><term>Multiple Sclerosis (therapy)</term><term>Time Factors</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Encéphale (physiopathologie)</term><term>Facteurs temps</term><term>Humains</term><term>Sclérose en plaques ()</term><term>Sclérose en plaques (diagnostic)</term><term>Sclérose en plaques (physiopathologie)</term><term>Sclérose en plaques (économie)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Multiple Sclerosis</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Sclérose en plaques</term></keywords><keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>Multiple Sclerosis</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Encéphale</term><term>Sclérose en plaques</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term><term>Multiple Sclerosis</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Multiple Sclerosis</term></keywords><keywords scheme="MESH" qualifier="économie" xml:lang="fr"><term>Sclérose en plaques</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Time Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Facteurs temps</term><term>Humains</term><term>Sclérose en plaques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We present international consensus recommendations for improving diagnosis, management and treatment access in multiple sclerosis (MS). Our vision is that these will be used widely among those committed to creating a better future for people with MS and their families.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27640924</PMID><DateCreated><Year>2016</Year><Month>09</Month><Day>19</Day></DateCreated><DateCompleted><Year>2017</Year><Month>02</Month><Day>24</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>24</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2211-0356</ISSN><JournalIssue CitedMedium="Internet"><Volume>9 Suppl 1</Volume><PubDate><Year>2016</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Multiple sclerosis and related disorders</Title><ISOAbbreviation>Mult Scler Relat Disord</ISOAbbreviation></Journal><ArticleTitle>Brain health: time matters in multiple sclerosis.</ArticleTitle><Pagination><MedlinePgn>S5-S48</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.msard.2016.07.003</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S2211-0348(16)30102-X</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">We present international consensus recommendations for improving diagnosis, management and treatment access in multiple sclerosis (MS). Our vision is that these will be used widely among those committed to creating a better future for people with MS and their families.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Structured discussions and literature searches conducted in 2015 examined the personal and economic impact of MS, current practice in diagnosis, treatment and management, definitions of disease activity and barriers to accessing disease-modifying therapies (DMTs).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Delays often occur before a person with symptoms suggestive of MS sees a neurologist. Campaigns to raise awareness of MS are needed, as are initiatives to improve access to MS healthcare professionals and services. We recommend a clear treatment goal: to maximize neurological reserve, cognitive function and physical function by reducing disease activity. Treatment should start early, with DMT and lifestyle measures. All parameters that predict relapses and disability progression should be included in the definition of disease activity and monitored regularly when practical. On suboptimal control of disease activity, switching to a DMT with a different mechanism of action should be considered. A shared decision-making process that embodies dialogue and considers all appropriate DMTs should be implemented. Monitoring data should be recorded formally in registries to generate real-world evidence. In many jurisdictions, access to DMTs is limited. To improve treatment access the relevant bodies should consider all costs to all parties when conducting economic evaluations and encourage the continuing investigation, development and use of cost-effective therapeutic strategies and alternative financing models.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The consensus findings of an international author group recommend a therapeutic strategy based on proactive monitoring and shared decision-making in MS. Early diagnosis and improved treatment access are also key components.</AbstractText><CopyrightInformation>Copyright © 2016 Oxford PharmaGenesis Ltd. Published by Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Giovannoni</LastName><ForeName>Gavin</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Queen Mary University London, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, UK. Electronic address: g.giovannoni@qmul.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Butzkueven</LastName><ForeName>Helmut</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia. Electronic address: butz@unimelb.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dhib-Jalbut</LastName><ForeName>Suhayl</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Neurology, RUTGERS-Robert Wood Johnson Medical School, New Brunswick, NJ, USA. Electronic address: jalbutsu@rwjms.rutgers.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hobart</LastName><ForeName>Jeremy</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK. Electronic address: jeremy.hobart@plymouth.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kobelt</LastName><ForeName>Gisela</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>European Health Economics, Mulhouse, France. Electronic address: kobelt.gisele@wanadoo.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pepper</LastName><ForeName>George</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Shift.ms, Leeds, UK. Electronic address: george@shift.ms.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sormani</LastName><ForeName>Maria Pia</ForeName><Initials>MP</Initials><AffiliationInfo><Affiliation>Biostatistics Unit, University of Genoa, Genoa, Italy. Electronic address: mariapia.sormani@unige.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thalheim</LastName><ForeName>Christoph</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Patient Advocate in Multiple Sclerosis, Brussels, Belgium. Electronic address: christoph.thalheim@emsp.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Traboulsee</LastName><ForeName>Anthony</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address: t.traboulsee@ubc.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vollmer</LastName><ForeName>Timothy</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Neurology, University of Colorado Denver, Aurora, CO, USA. Electronic address: Timothy.Vollmer@ucdenver.edu.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>07</Month><Day>07</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Mult Scler Relat Disord</MedlineTA><NlmUniqueID>101580247</NlmUniqueID><ISSNLinking>2211-0348</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001921" MajorTopicYN="N">Brain</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009103" MajorTopicYN="N">Multiple Sclerosis</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Consensus statement</Keyword><Keyword MajorTopicYN="N">Disease activity</Keyword><Keyword MajorTopicYN="N">Disease-modifying therapy (DMT)</Keyword><Keyword MajorTopicYN="N">Magnetic resonance imaging (MRI)</Keyword><Keyword MajorTopicYN="N">Multiple sclerosis</Keyword><Keyword MajorTopicYN="N">Treatment strategy</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>06</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>07</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>9</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>9</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>2</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27640924</ArticleId><ArticleId IdType="pii">S2211-0348(16)30102-X</ArticleId><ArticleId IdType="doi">10.1016/j.msard.2016.07.003</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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