ECMO Cardio-Pulmonary Resuscitation (ECPR), trends in survival from an international multicentre cohort study over 12-years.
Identifieur interne : 001035 ( PubMed/Curation ); précédent : 001034; suivant : 001036ECMO Cardio-Pulmonary Resuscitation (ECPR), trends in survival from an international multicentre cohort study over 12-years.
Auteurs : Alexander Sacha C. Richardson [Australie] ; Matthieu Schmidt [France] ; Michael Bailey [Australie] ; Vincent A. Pellegrino [Australie] ; Peter T. Rycus [États-Unis] ; David V. Pilcher [Australie]Source :
- Resuscitation [ 1873-1570 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Analyse de survie, Arrêt cardiaque (), Arrêt cardiaque (mortalité), Enregistrements, Facteurs de risque, Facteurs temps, Femelle, Humains, Indice de gravité médicale, Modèles logistiques, Mâle, Oxygénation extracorporelle sur oxygénateur à membrane (mortalité), Oxygénation extracorporelle sur oxygénateur à membrane (tendances), Réanimation cardiopulmonaire (mortalité), Réanimation cardiopulmonaire (tendances), Résultat thérapeutique, Sujet âgé, Taux de survie, Études de cohortes.
- MESH :
- mortalité : Arrêt cardiaque, Oxygénation extracorporelle sur oxygénateur à membrane, Réanimation cardiopulmonaire.
- tendances : Oxygénation extracorporelle sur oxygénateur à membrane, Réanimation cardiopulmonaire.
- Adulte, Adulte d'âge moyen, Analyse de survie, Arrêt cardiaque, Enregistrements, Facteurs de risque, Facteurs temps, Femelle, Humains, Indice de gravité médicale, Modèles logistiques, Mâle, Résultat thérapeutique, Sujet âgé, Taux de survie, Études de cohortes.
English descriptors
- KwdEn :
- Adult, Aged, Cardiopulmonary Resuscitation (mortality), Cardiopulmonary Resuscitation (trends), Cohort Studies, Extracorporeal Membrane Oxygenation (mortality), Extracorporeal Membrane Oxygenation (trends), Female, Heart Arrest (mortality), Heart Arrest (therapy), Humans, Logistic Models, Male, Middle Aged, Registries, Risk Factors, Severity of Illness Index, Survival Analysis, Survival Rate, Time Factors, Treatment Outcome.
- MESH :
- mortality : Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation, Heart Arrest.
- therapy : Heart Arrest.
- trends : Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation.
- Adult, Aged, Cohort Studies, Female, Humans, Logistic Models, Male, Middle Aged, Registries, Risk Factors, Severity of Illness Index, Survival Analysis, Survival Rate, Time Factors, Treatment Outcome.
Abstract
Use of Extracorporeal Membrane Oxygenation during cardiopulmonary resuscitation (ECPR) is increasingly being deployed as an adjunct to conventional CPR. It is unknown if this has been associated with improved outcomes.
DOI: 10.1016/j.resuscitation.2016.12.009
PubMed: 27993632
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pubmed:27993632Le document en format XML
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<term>Cohort Studies</term>
<term>Extracorporeal Membrane Oxygenation (mortality)</term>
<term>Extracorporeal Membrane Oxygenation (trends)</term>
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<term>Femelle</term>
<term>Humains</term>
<term>Indice de gravité médicale</term>
<term>Modèles logistiques</term>
<term>Mâle</term>
<term>Oxygénation extracorporelle sur oxygénateur à membrane (mortalité)</term>
<term>Oxygénation extracorporelle sur oxygénateur à membrane (tendances)</term>
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<term>Taux de survie</term>
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<term>Extracorporeal Membrane Oxygenation</term>
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<term>Oxygénation extracorporelle sur oxygénateur à membrane</term>
<term>Réanimation cardiopulmonaire</term>
</keywords>
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<term>Réanimation cardiopulmonaire</term>
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<term>Extracorporeal Membrane Oxygenation</term>
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<term>Aged</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Logistic Models</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Registries</term>
<term>Risk Factors</term>
<term>Severity of Illness Index</term>
<term>Survival Analysis</term>
<term>Survival Rate</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
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<term>Adulte d'âge moyen</term>
<term>Analyse de survie</term>
<term>Arrêt cardiaque</term>
<term>Enregistrements</term>
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<term>Facteurs temps</term>
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<front><div type="abstract" xml:lang="en">Use of Extracorporeal Membrane Oxygenation during cardiopulmonary resuscitation (ECPR) is increasingly being deployed as an adjunct to conventional CPR. It is unknown if this has been associated with improved outcomes.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27993632</PMID>
<DateCreated><Year>2016</Year>
<Month>12</Month>
<Day>20</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>07</Month>
<Day>10</Day>
</DateCompleted>
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<Month>07</Month>
<Day>28</Day>
</DateRevised>
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<JournalIssue CitedMedium="Internet"><Volume>112</Volume>
<PubDate><Year>2017</Year>
<Month>Mar</Month>
</PubDate>
</JournalIssue>
<Title>Resuscitation</Title>
<ISOAbbreviation>Resuscitation</ISOAbbreviation>
</Journal>
<ArticleTitle>ECMO Cardio-Pulmonary Resuscitation (ECPR), trends in survival from an international multicentre cohort study over 12-years.</ArticleTitle>
<Pagination><MedlinePgn>34-40</MedlinePgn>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Use of Extracorporeal Membrane Oxygenation during cardiopulmonary resuscitation (ECPR) is increasingly being deployed as an adjunct to conventional CPR. It is unknown if this has been associated with improved outcomes.</AbstractText>
<AbstractText Label="AIMS" NlmCategory="OBJECTIVE">To describe trends in survival and patient demographics for ECPR patients in the international Extracorporeal Life Support Organisation (ELSO) database over the past 12 years and identify factors associated with changes in survival.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Patients greater than 16 years of age who received ECPR between January 2003 and December 2014 were extracted from the ELSO registry and were divided into three 4-year cohorts (Cohort 1: 2003-2006, Cohort 2: 2007-2010, Cohort 3: 2011-2014). Univariable analysis was performed to compare demographics and outcomes of patients across the three cohorts. Univariable and multivariable analyses were then performed to identify factors independently associated with survival.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">1796 patients treated with ECPR were extracted from the registry, aged 50 (±18.5) years. Annual ECPR episodes increased over 10-fold, from 35 to over 400 per year. Survival to hospital discharge was 29% overall (27% cohort 1, 28% cohort 2, 30% cohort 3 (p=0.71)). Age, body weight and documented comorbidities increased over time. There was a reduction in complications associated with ECMO usage. After adjusting for confounders there was no change in the odds of survival over the time period examined.</AbstractText>
<AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">Over the period 2003-2014, survival to hospital discharge was 29% for patients who require ECPR. Despite advances in provision of ECMO care and increasing co-morbidities of patients, there has been no change in risk-adjusted survival over time.</AbstractText>
<CopyrightInformation>Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Richardson</LastName>
<ForeName>Alexander Sacha C</ForeName>
<Initials>AS</Initials>
<AffiliationInfo><Affiliation>Department of Intensive Care and Hyperbaric Medicine, Alfred Hospital, Prahran, Melbourne, Australia. Electronic address: s.richardson@doctors.org.uk.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schmidt</LastName>
<ForeName>Matthieu</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Medical-Surgical Intensive Care Unit, iCAN, Institute of Cardiometabolism and Nutrition, Hopital de la Pitié-Salpetrière, Assistance Publique-Hôpitaux de Paris, Université Pierre et Marie Curie, 47-83 bd de l'Hopital, Paris 75651, France.</Affiliation>
</AffiliationInfo>
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<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health, Monash University, Melbourne, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pellegrino</LastName>
<ForeName>Vincent A</ForeName>
<Initials>VA</Initials>
<AffiliationInfo><Affiliation>Department of Intensive Care and Hyperbaric Medicine, Alfred Hospital, Prahran, Melbourne, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rycus</LastName>
<ForeName>Peter T</ForeName>
<Initials>PT</Initials>
<AffiliationInfo><Affiliation>Extracorporeal Life Support Organization, Ann Arbor, MI, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pilcher</LastName>
<ForeName>David V</ForeName>
<Initials>DV</Initials>
<AffiliationInfo><Affiliation>Department of Intensive Care and Hyperbaric Medicine, Alfred Hospital, Prahran, Melbourne, Australia.</Affiliation>
</AffiliationInfo>
</Author>
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<Month>12</Month>
<Day>16</Day>
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<MedlineTA>Resuscitation</MedlineTA>
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<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>J Thorac Dis. 2017 Jun;9(6):1415-1419</RefSource>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016887" MajorTopicYN="N">Cardiopulmonary Resuscitation</DescriptorName>
<QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName>
<QualifierName UI="Q000639" MajorTopicYN="N">trends</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName>
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<QualifierName UI="Q000639" MajorTopicYN="N">trends</QualifierName>
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<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<MeshHeading><DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName>
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<MeshHeading><DescriptorName UI="D016019" MajorTopicYN="N">Survival Analysis</DescriptorName>
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<MeshHeading><DescriptorName UI="D015996" MajorTopicYN="N">Survival Rate</DescriptorName>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">CPR</Keyword>
<Keyword MajorTopicYN="N">Cardio Pulmonary Resuscitation</Keyword>
<Keyword MajorTopicYN="N">ECMO</Keyword>
<Keyword MajorTopicYN="N">ECMO-CPR</Keyword>
<Keyword MajorTopicYN="N">ECPR</Keyword>
<Keyword MajorTopicYN="N">ELSO</Keyword>
<Keyword MajorTopicYN="N">Extra Corporeal Membrane Oxygenation (ECMO)</Keyword>
<Keyword MajorTopicYN="N">Extra-Corporeal Membrane Oxygenation</Keyword>
<Keyword MajorTopicYN="N">Extra-Corporeal Membrane Oxygenation assisted Cardio Pulmonary Resuscitation</Keyword>
<Keyword MajorTopicYN="N">Extracorporeal Life Support Organisation</Keyword>
<Keyword MajorTopicYN="N">SAVE score</Keyword>
<Keyword MajorTopicYN="N">VA</Keyword>
<Keyword MajorTopicYN="N">VV</Keyword>
<Keyword MajorTopicYN="N">survival after VA-ECMO score</Keyword>
<Keyword MajorTopicYN="N">veno-arterial</Keyword>
<Keyword MajorTopicYN="N">veno-venous</Keyword>
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