Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery.
Identifieur interne : 000D49 ( PubMed/Curation ); précédent : 000D48; suivant : 000D50Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery.
Auteurs : P J Devereaux [Canada] ; Bruce M. Biccard [Afrique du Sud] ; Alben Sigamani [Inde] ; Denis Xavier [Inde] ; Matthew T V. Chan [République populaire de Chine] ; Sadeesh K. Srinathan [Canada] ; Michael Walsh [Canada] ; Valsa Abraham [Inde] ; Rupert Pearse [Royaume-Uni] ; C Y Wang [Malaisie] ; Daniel I. Sessler [États-Unis] ; Andrea Kurz [États-Unis] ; Wojciech Szczeklik [Pologne] ; Otavio Berwanger [Brésil] ; Juan Carlos Villar [Colombie] ; German Malaga [Pérou] ; Amit X. Garg [Canada] ; Clara K. Chow [Australie] ; Gareth Ackland [Royaume-Uni] ; Ameen Patel [Canada] ; Flavia Kessler Borges [Brésil] ; Emilie P. Belley-Cote [Canada] ; Emmanuelle Duceppe [Canada] ; Jessica Spence [Canada] ; Vikas Tandon [Canada] ; Colin Williams [Royaume-Uni] ; Robert J. Sapsford [Royaume-Uni] ; Carisi A. Polanczyk [Brésil] ; Maria Tiboni [Canada] ; Pablo Alonso-Coello [Espagne] ; Atiya Faruqui [Inde] ; Diane Heels-Ansdell [Canada] ; Andre Lamy [Canada] ; Richard Whitlock [Canada] ; Yannick Lemanach [Canada] ; Pavel S. Roshanov [Canada] ; Michael Mcgillion [Canada] ; Peter Kavsak [Canada] ; Matthew J. Mcqueen [Canada] ; Lehana Thabane [Canada] ; Reitze N. Rodseth [Afrique du Sud] ; Giovanna A Lurati Buse [Allemagne] ; Mohit Bhandari [Canada] ; Ignacia Garutti [Espagne] ; Michael J. Jacka [Canada] ; Holger J. Schünemann [Canada] ; Olga Lucía Cortes [Colombie] ; Pierre Coriat [France] ; Nazari Dvirnik [Canada] ; Fernando Botto [Argentine] ; Shirley Pettit [Canada] ; Allan S. Jaffe [États-Unis] ; Gordon H. Guyatt [Canada]Source :
- JAMA [ 1538-3598 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Troponin T.
- mortality : Myocardial Infarction, Myocardial Ischemia.
- Aged, Female, Humans, Male, Middle Aged, Postoperative Complications, Postoperative Period, Prospective Studies, Risk Assessment.
Abstract
Little is known about the relationship between perioperative high-sensitivity troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac surgery (MINS).
DOI: 10.1001/jama.2017.4360
PubMed: 28444280
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Roshanov</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Mcgillion, Michael" sort="Mcgillion, Michael" uniqKey="Mcgillion M" first="Michael" last="Mcgillion">Michael Mcgillion</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Kavsak, Peter" sort="Kavsak, Peter" uniqKey="Kavsak P" first="Peter" last="Kavsak">Peter Kavsak</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Mcqueen, Matthew J" sort="Mcqueen, Matthew J" uniqKey="Mcqueen M" first="Matthew J" last="Mcqueen">Matthew J. Mcqueen</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Thabane, Lehana" sort="Thabane, Lehana" uniqKey="Thabane L" first="Lehana" last="Thabane">Lehana Thabane</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Rodseth, Reitze N" sort="Rodseth, Reitze N" uniqKey="Rodseth R" first="Reitze N" last="Rodseth">Reitze N. 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Jacka</name><affiliation wicri:level="1"><nlm:affiliation>University of Alberta, Edmonton, Alberta, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of Alberta, Edmonton, Alberta</wicri:regionArea></affiliation></author><author><name sortKey="Schunemann, Holger J" sort="Schunemann, Holger J" uniqKey="Schunemann H" first="Holger J" last="Schünemann">Holger J. 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Jaffe</name><affiliation wicri:level="2"><nlm:affiliation>Mayo Clinic, Rochester, Minnesota.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Guyatt, Gordon H" sort="Guyatt, Gordon H" uniqKey="Guyatt G" first="Gordon H" last="Guyatt">Gordon H. Guyatt</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28444280</idno><idno type="pmid">28444280</idno><idno type="doi">10.1001/jama.2017.4360</idno><idno type="wicri:Area/PubMed/Corpus">000D52</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D52</idno><idno type="wicri:Area/PubMed/Curation">000D49</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000D49</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery.</title><author><name sortKey="Devereaux, P J" sort="Devereaux, P J" uniqKey="Devereaux P" first="P J" last="Devereaux">P J Devereaux</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Biccard, Bruce M" sort="Biccard, Bruce M" uniqKey="Biccard B" first="Bruce M" last="Biccard">Bruce M. Biccard</name><affiliation wicri:level="1"><nlm:affiliation>University of Cape Town, Cape Town, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of Cape Town, Cape Town</wicri:regionArea></affiliation></author><author><name sortKey="Sigamani, Alben" sort="Sigamani, Alben" uniqKey="Sigamani A" first="Alben" last="Sigamani">Alben Sigamani</name><affiliation wicri:level="1"><nlm:affiliation>Narayana Hrudayalaya Limited, Bangalore, Karnataka, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Narayana Hrudayalaya Limited, Bangalore, Karnataka</wicri:regionArea></affiliation></author><author><name sortKey="Xavier, Denis" sort="Xavier, Denis" uniqKey="Xavier D" first="Denis" last="Xavier">Denis Xavier</name><affiliation wicri:level="1"><nlm:affiliation>St John's Medical College and Research Institute, Bangalore, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>St John's Medical College and Research Institute, Bangalore</wicri:regionArea></affiliation></author><author><name sortKey="Chan, Matthew T V" sort="Chan, Matthew T V" uniqKey="Chan M" first="Matthew T V" last="Chan">Matthew T V. Chan</name><affiliation wicri:level="1"><nlm:affiliation>Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Chinese University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea></affiliation></author><author><name sortKey="Srinathan, Sadeesh K" sort="Srinathan, Sadeesh K" uniqKey="Srinathan S" first="Sadeesh K" last="Srinathan">Sadeesh K. Srinathan</name><affiliation wicri:level="1"><nlm:affiliation>Winnipeg Health Sciences Centre, University of Manitoba, Winnipeg, Manitoba, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Winnipeg Health Sciences Centre, University of Manitoba, Winnipeg, Manitoba</wicri:regionArea></affiliation></author><author><name sortKey="Walsh, Michael" sort="Walsh, Michael" uniqKey="Walsh M" first="Michael" last="Walsh">Michael Walsh</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Abraham, Valsa" sort="Abraham, Valsa" uniqKey="Abraham V" first="Valsa" last="Abraham">Valsa Abraham</name><affiliation wicri:level="1"><nlm:affiliation>Christian Medical College, Ludhiana, Punjab, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Christian Medical College, Ludhiana, Punjab</wicri:regionArea></affiliation></author><author><name sortKey="Pearse, Rupert" sort="Pearse, Rupert" uniqKey="Pearse R" first="Rupert" last="Pearse">Rupert Pearse</name><affiliation wicri:level="2"><nlm:affiliation>Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:cityArea></affiliation></author><author><name sortKey="Wang, C Y" sort="Wang, C Y" uniqKey="Wang C" first="C Y" last="Wang">C Y Wang</name><affiliation wicri:level="1"><nlm:affiliation>University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>University of Malaya, Kuala Lumpur</wicri:regionArea></affiliation></author><author><name sortKey="Sessler, Daniel I" sort="Sessler, Daniel I" uniqKey="Sessler D" first="Daniel I" last="Sessler">Daniel I. Sessler</name><affiliation wicri:level="2"><nlm:affiliation>Cleveland Clinic, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Kurz, Andrea" sort="Kurz, Andrea" uniqKey="Kurz A" first="Andrea" last="Kurz">Andrea Kurz</name><affiliation wicri:level="2"><nlm:affiliation>Cleveland Clinic, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Szczeklik, Wojciech" sort="Szczeklik, Wojciech" uniqKey="Szczeklik W" first="Wojciech" last="Szczeklik">Wojciech Szczeklik</name><affiliation wicri:level="1"><nlm:affiliation>Jagiellonian University Medical College, Krakow, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Jagiellonian University Medical College, Krakow</wicri:regionArea></affiliation></author><author><name sortKey="Berwanger, Otavio" sort="Berwanger, Otavio" uniqKey="Berwanger O" first="Otavio" last="Berwanger">Otavio Berwanger</name><affiliation wicri:level="1"><nlm:affiliation>Research Institute Hcor (Hospital do Coracao), Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Research Institute Hcor (Hospital do Coracao), Sao Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Villar, Juan Carlos" sort="Villar, Juan Carlos" uniqKey="Villar J" first="Juan Carlos" last="Villar">Juan Carlos Villar</name><affiliation wicri:level="1"><nlm:affiliation>Universidad Autónoma de Bucaramanga and Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Universidad Autónoma de Bucaramanga and Fundación Cardioinfantil-Instituto de Cardiología, Bogotá</wicri:regionArea></affiliation></author><author><name sortKey="Malaga, German" sort="Malaga, German" uniqKey="Malaga G" first="German" last="Malaga">German Malaga</name><affiliation wicri:level="1"><nlm:affiliation>Universidad Peruana Cayetano Heredia, Lima, Peru.</nlm:affiliation><country xml:lang="fr">Pérou</country><wicri:regionArea>Universidad Peruana Cayetano Heredia, Lima</wicri:regionArea></affiliation></author><author><name sortKey="Garg, Amit X" sort="Garg, Amit X" uniqKey="Garg A" first="Amit X" last="Garg">Amit X. Garg</name><affiliation wicri:level="1"><nlm:affiliation>Western University, London, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Western University, London, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Chow, Clara K" sort="Chow, Clara K" uniqKey="Chow C" first="Clara K" last="Chow">Clara K. Chow</name><affiliation wicri:level="1"><nlm:affiliation>The George Institute for Global Health, Westmead Hospital, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The George Institute for Global Health, Westmead Hospital, University of Sydney, Sydney</wicri:regionArea></affiliation></author><author><name sortKey="Ackland, Gareth" sort="Ackland, Gareth" uniqKey="Ackland G" first="Gareth" last="Ackland">Gareth Ackland</name><affiliation wicri:level="1"><nlm:affiliation>University College Hospital NHS Trust and William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University College Hospital NHS Trust and William Harvey Research Institute, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Patel, Ameen" sort="Patel, Ameen" uniqKey="Patel A" first="Ameen" last="Patel">Ameen Patel</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Borges, Flavia Kessler" sort="Borges, Flavia Kessler" uniqKey="Borges F" first="Flavia Kessler" last="Borges">Flavia Kessler Borges</name><affiliation wicri:level="1"><nlm:affiliation>Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre</wicri:regionArea></affiliation></author><author><name sortKey="Belley Cote, Emilie P" sort="Belley Cote, Emilie P" uniqKey="Belley Cote E" first="Emilie P" last="Belley-Cote">Emilie P. Belley-Cote</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Duceppe, Emmanuelle" sort="Duceppe, Emmanuelle" uniqKey="Duceppe E" first="Emmanuelle" last="Duceppe">Emmanuelle Duceppe</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Spence, Jessica" sort="Spence, Jessica" uniqKey="Spence J" first="Jessica" last="Spence">Jessica Spence</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Tandon, Vikas" sort="Tandon, Vikas" uniqKey="Tandon V" first="Vikas" last="Tandon">Vikas Tandon</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Williams, Colin" sort="Williams, Colin" uniqKey="Williams C" first="Colin" last="Williams">Colin Williams</name><affiliation wicri:level="2"><nlm:affiliation>Royal Liverpool and Broadgreen University Hospitals, Liverpool, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Royal Liverpool and Broadgreen University Hospitals, Liverpool</wicri:cityArea></affiliation></author><author><name sortKey="Sapsford, Robert J" sort="Sapsford, Robert J" uniqKey="Sapsford R" first="Robert J" last="Sapsford">Robert J. Sapsford</name><affiliation wicri:level="2"><nlm:affiliation>Leeds Teaching Hospitals NHS Trust, Leeds, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Leeds Teaching Hospitals NHS Trust, Leeds</wicri:cityArea></affiliation></author><author><name sortKey="Polanczyk, Carisi A" sort="Polanczyk, Carisi A" uniqKey="Polanczyk C" first="Carisi A" last="Polanczyk">Carisi A. Polanczyk</name><affiliation wicri:level="1"><nlm:affiliation>Federal University of Rio Grande do Sul and Hospital Moinhos de Vento, Porto Alegre, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Federal University of Rio Grande do Sul and Hospital Moinhos de Vento, Porto Alegre</wicri:regionArea></affiliation></author><author><name sortKey="Tiboni, Maria" sort="Tiboni, Maria" uniqKey="Tiboni M" first="Maria" last="Tiboni">Maria Tiboni</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Alonso Coello, Pablo" sort="Alonso Coello, Pablo" uniqKey="Alonso Coello P" first="Pablo" last="Alonso-Coello">Pablo Alonso-Coello</name><affiliation wicri:level="1"><nlm:affiliation>Iberoamerican Cochrane Center (IIB Sant Pau-CIBERESP), Hospital Sant Pau, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Iberoamerican Cochrane Center (IIB Sant Pau-CIBERESP), Hospital Sant Pau, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Faruqui, Atiya" sort="Faruqui, Atiya" uniqKey="Faruqui A" first="Atiya" last="Faruqui">Atiya Faruqui</name><affiliation wicri:level="1"><nlm:affiliation>St John's Medical College and Research Institute, Bangalore, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>St John's Medical College and Research Institute, Bangalore</wicri:regionArea></affiliation></author><author><name sortKey="Heels Ansdell, Diane" sort="Heels Ansdell, Diane" uniqKey="Heels Ansdell D" first="Diane" last="Heels-Ansdell">Diane Heels-Ansdell</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Lamy, Andre" sort="Lamy, Andre" uniqKey="Lamy A" first="Andre" last="Lamy">Andre Lamy</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Whitlock, Richard" sort="Whitlock, Richard" uniqKey="Whitlock R" first="Richard" last="Whitlock">Richard Whitlock</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Lemanach, Yannick" sort="Lemanach, Yannick" uniqKey="Lemanach Y" first="Yannick" last="Lemanach">Yannick Lemanach</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Roshanov, Pavel S" sort="Roshanov, Pavel S" uniqKey="Roshanov P" first="Pavel S" last="Roshanov">Pavel S. Roshanov</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Mcgillion, Michael" sort="Mcgillion, Michael" uniqKey="Mcgillion M" first="Michael" last="Mcgillion">Michael Mcgillion</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Kavsak, Peter" sort="Kavsak, Peter" uniqKey="Kavsak P" first="Peter" last="Kavsak">Peter Kavsak</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Mcqueen, Matthew J" sort="Mcqueen, Matthew J" uniqKey="Mcqueen M" first="Matthew J" last="Mcqueen">Matthew J. Mcqueen</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Thabane, Lehana" sort="Thabane, Lehana" uniqKey="Thabane L" first="Lehana" last="Thabane">Lehana Thabane</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Rodseth, Reitze N" sort="Rodseth, Reitze N" uniqKey="Rodseth R" first="Reitze N" last="Rodseth">Reitze N. Rodseth</name><affiliation wicri:level="1"><nlm:affiliation>University of KwaZulu-Natal, Pietermaritzburg, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of KwaZulu-Natal, Pietermaritzburg</wicri:regionArea></affiliation></author><author><name sortKey="Buse, Giovanna A Lurati" sort="Buse, Giovanna A Lurati" uniqKey="Buse G" first="Giovanna A Lurati" last="Buse">Giovanna A Lurati Buse</name><affiliation wicri:level="1"><nlm:affiliation>University Hospital Düsseldorf, Düsseldorf, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital Düsseldorf, Düsseldorf</wicri:regionArea></affiliation></author><author><name sortKey="Bhandari, Mohit" sort="Bhandari, Mohit" uniqKey="Bhandari M" first="Mohit" last="Bhandari">Mohit Bhandari</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Garutti, Ignacia" sort="Garutti, Ignacia" uniqKey="Garutti I" first="Ignacia" last="Garutti">Ignacia Garutti</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Universitario Gregorio Marañón, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Jacka, Michael J" sort="Jacka, Michael J" uniqKey="Jacka M" first="Michael J" last="Jacka">Michael J. Jacka</name><affiliation wicri:level="1"><nlm:affiliation>University of Alberta, Edmonton, Alberta, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>University of Alberta, Edmonton, Alberta</wicri:regionArea></affiliation></author><author><name sortKey="Schunemann, Holger J" sort="Schunemann, Holger J" uniqKey="Schunemann H" first="Holger J" last="Schünemann">Holger J. Schünemann</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Cortes, Olga Lucia" sort="Cortes, Olga Lucia" uniqKey="Cortes O" first="Olga Lucía" last="Cortes">Olga Lucía Cortes</name><affiliation wicri:level="1"><nlm:affiliation>Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Fundación Cardioinfantil-Instituto de Cardiología, Bogotá</wicri:regionArea></affiliation></author><author><name sortKey="Coriat, Pierre" sort="Coriat, Pierre" uniqKey="Coriat P" first="Pierre" last="Coriat">Pierre Coriat</name><affiliation wicri:level="1"><nlm:affiliation>Universite Pierre et Marie Curie, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Universite Pierre et Marie Curie, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Dvirnik, Nazari" sort="Dvirnik, Nazari" uniqKey="Dvirnik N" first="Nazari" last="Dvirnik">Nazari Dvirnik</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Botto, Fernando" sort="Botto, Fernando" uniqKey="Botto F" first="Fernando" last="Botto">Fernando Botto</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Universitario Austral, Pilar, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Hospital Universitario Austral, Pilar, Buenos Aires</wicri:regionArea></affiliation></author><author><name sortKey="Pettit, Shirley" sort="Pettit, Shirley" uniqKey="Pettit S" first="Shirley" last="Pettit">Shirley Pettit</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Jaffe, Allan S" sort="Jaffe, Allan S" uniqKey="Jaffe A" first="Allan S" last="Jaffe">Allan S. Jaffe</name><affiliation wicri:level="2"><nlm:affiliation>Mayo Clinic, Rochester, Minnesota.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Guyatt, Gordon H" sort="Guyatt, Gordon H" uniqKey="Guyatt G" first="Gordon H" last="Guyatt">Gordon H. Guyatt</name><affiliation wicri:level="1"><nlm:affiliation>McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author></analytic><series><title level="j">JAMA</title><idno type="eISSN">1538-3598</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Myocardial Infarction (mortality)</term><term>Myocardial Ischemia (mortality)</term><term>Postoperative Complications</term><term>Postoperative Period</term><term>Prospective Studies</term><term>Risk Assessment</term><term>Troponin T (blood)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Complications postopératoires</term><term>Femelle</term><term>Humains</term><term>Infarctus du myocarde (mortalité)</term><term>Ischémie myocardique (mortalité)</term><term>Mâle</term><term>Période postopératoire</term><term>Sujet âgé</term><term>Troponine T (sang)</term><term>Études prospectives</term><term>Évaluation des risques</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Troponin T</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Myocardial Infarction</term><term>Myocardial Ischemia</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Infarctus du myocarde</term><term>Ischémie myocardique</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Troponine T</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Postoperative Complications</term><term>Postoperative Period</term><term>Prospective Studies</term><term>Risk Assessment</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Complications postopératoires</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Période postopératoire</term><term>Sujet âgé</term><term>Études prospectives</term><term>Évaluation des risques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Little is known about the relationship between perioperative high-sensitivity troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac surgery (MINS).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28444280</PMID><DateCreated><Year>2017</Year><Month>04</Month><Day>26</Day></DateCreated><DateCompleted><Year>2017</Year><Month>07</Month><Day>06</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>24</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1538-3598</ISSN><JournalIssue CitedMedium="Internet"><Volume>317</Volume><Issue>16</Issue><PubDate><Year>2017</Year><Month>Apr</Month><Day>25</Day></PubDate></JournalIssue><Title>JAMA</Title><ISOAbbreviation>JAMA</ISOAbbreviation></Journal><ArticleTitle>Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery.</ArticleTitle><Pagination><MedlinePgn>1642-1651</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1001/jama.2017.4360</ELocationID><Abstract><AbstractText Label="Importance" NlmCategory="UNASSIGNED">Little is known about the relationship between perioperative high-sensitivity troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac surgery (MINS).</AbstractText><AbstractText Label="Objective" NlmCategory="UNASSIGNED">To determine the association between perioperative hsTnT measurements and 30-day mortality and potential diagnostic criteria for MINS (ie, myocardial injury due to ischemia associated with 30-day mortality).</AbstractText><AbstractText Label="Design, Setting, and Participants" NlmCategory="UNASSIGNED">Prospective cohort study of patients aged 45 years or older who underwent inpatient noncardiac surgery and had a postoperative hsTnT measurement. Starting in October 2008, participants were recruited at 23 centers in 13 countries; follow-up finished in December 2013.</AbstractText><AbstractText Label="Exposures" NlmCategory="UNASSIGNED">Patients had hsTnT measurements 6 to 12 hours after surgery and daily for 3 days; 40.4% had a preoperative hsTnT measurement.</AbstractText><AbstractText Label="Main Outcomes and Measures" NlmCategory="UNASSIGNED">A modified Mazumdar approach (an iterative process) was used to determine if there were hsTnT thresholds associated with risk of death and had an adjusted hazard ratio (HR) of 3.0 or higher and a risk of 30-day mortality of 3% or higher. To determine potential diagnostic criteria for MINS, regression analyses ascertained if postoperative hsTnT elevations required an ischemic feature (eg, ischemic symptom or electrocardiography finding) to be associated with 30-day mortality.</AbstractText><AbstractText Label="Results" NlmCategory="UNASSIGNED">Among 21 842 participants, the mean age was 63.1 (SD, 10.7) years and 49.1% were female. Death within 30 days after surgery occurred in 266 patients (1.2%; 95% CI, 1.1%-1.4%). Multivariable analysis demonstrated that compared with the reference group (peak hsTnT <5 ng/L), peak postoperative hsTnT levels of 20 to less than 65 ng/L, 65 to less than 1000 ng/L, and 1000 ng/L or higher had 30-day mortality rates of 3.0% (123/4049; 95% CI, 2.6%-3.6%), 9.1% (102/1118; 95% CI, 7.6%-11.0%), and 29.6% (16/54; 95% CI, 19.1%-42.8%), with corresponding adjusted HRs of 23.63 (95% CI, 10.32-54.09), 70.34 (95% CI, 30.60-161.71), and 227.01 (95% CI, 87.35-589.92), respectively. An absolute hsTnT change of 5 ng/L or higher was associated with an increased risk of 30-day mortality (adjusted HR, 4.69; 95% CI, 3.52-6.25). An elevated postoperative hsTnT (ie, 20 to <65 ng/L with an absolute change ≥5 ng/L or hsTnT ≥65 ng/L) without an ischemic feature was associated with 30-day mortality (adjusted HR, 3.20; 95% CI, 2.37-4.32). Among the 3904 patients (17.9%; 95% CI, 17.4%-18.4%) with MINS, 3633 (93.1%; 95% CI, 92.2%-93.8%) did not experience an ischemic symptom.</AbstractText><AbstractText Label="Conclusions and Relevance" NlmCategory="UNASSIGNED">Among patients undergoing noncardiac surgery, peak postoperative hsTnT during the first 3 days after surgery was significantly associated with 30-day mortality. Elevated postoperative hsTnT without an ischemic feature was also associated with 30-day mortality.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><CollectiveName>Writing Committee for the VISION Study Investigators</CollectiveName></Author><Author ValidYN="Y"><LastName>Devereaux</LastName><ForeName>P J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Biccard</LastName><ForeName>Bruce M</ForeName><Initials>BM</Initials><AffiliationInfo><Affiliation>University of Cape Town, Cape Town, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sigamani</LastName><ForeName>Alben</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Narayana Hrudayalaya Limited, Bangalore, Karnataka, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xavier</LastName><ForeName>Denis</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>St John's Medical College and Research Institute, Bangalore, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>Matthew T V</ForeName><Initials>MTV</Initials><AffiliationInfo><Affiliation>Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Srinathan</LastName><ForeName>Sadeesh K</ForeName><Initials>SK</Initials><AffiliationInfo><Affiliation>Winnipeg Health Sciences Centre, University of Manitoba, Winnipeg, Manitoba, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walsh</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abraham</LastName><ForeName>Valsa</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Christian Medical College, Ludhiana, Punjab, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pearse</LastName><ForeName>Rupert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, England.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>C Y</ForeName><Initials>CY</Initials><AffiliationInfo><Affiliation>University of Malaya, Kuala Lumpur, Malaysia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sessler</LastName><ForeName>Daniel I</ForeName><Initials>DI</Initials><AffiliationInfo><Affiliation>Cleveland Clinic, Cleveland, Ohio.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kurz</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Cleveland Clinic, Cleveland, Ohio.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Szczeklik</LastName><ForeName>Wojciech</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Jagiellonian University Medical College, Krakow, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Berwanger</LastName><ForeName>Otavio</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Research Institute Hcor (Hospital do Coracao), Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Villar</LastName><ForeName>Juan Carlos</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Universidad Autónoma de Bucaramanga and Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Malaga</LastName><ForeName>German</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Universidad Peruana Cayetano Heredia, Lima, Peru.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Garg</LastName><ForeName>Amit X</ForeName><Initials>AX</Initials><AffiliationInfo><Affiliation>Western University, London, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chow</LastName><ForeName>Clara K</ForeName><Initials>CK</Initials><AffiliationInfo><Affiliation>The George Institute for Global Health, Westmead Hospital, University of Sydney, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ackland</LastName><ForeName>Gareth</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>University College Hospital NHS Trust and William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Patel</LastName><ForeName>Ameen</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borges</LastName><ForeName>Flavia Kessler</ForeName><Initials>FK</Initials><AffiliationInfo><Affiliation>Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Belley-Cote</LastName><ForeName>Emilie P</ForeName><Initials>EP</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Duceppe</LastName><ForeName>Emmanuelle</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spence</LastName><ForeName>Jessica</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tandon</LastName><ForeName>Vikas</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Williams</LastName><ForeName>Colin</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Royal Liverpool and Broadgreen University Hospitals, Liverpool, England.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sapsford</LastName><ForeName>Robert J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>Leeds Teaching Hospitals NHS Trust, Leeds, England.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Polanczyk</LastName><ForeName>Carisi A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Federal University of Rio Grande do Sul and Hospital Moinhos de Vento, Porto Alegre, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tiboni</LastName><ForeName>Maria</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alonso-Coello</LastName><ForeName>Pablo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Iberoamerican Cochrane Center (IIB Sant Pau-CIBERESP), Hospital Sant Pau, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Faruqui</LastName><ForeName>Atiya</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>St John's Medical College and Research Institute, Bangalore, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heels-Ansdell</LastName><ForeName>Diane</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lamy</LastName><ForeName>Andre</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Whitlock</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>LeManach</LastName><ForeName>Yannick</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roshanov</LastName><ForeName>Pavel S</ForeName><Initials>PS</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McGillion</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kavsak</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McQueen</LastName><ForeName>Matthew J</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thabane</LastName><ForeName>Lehana</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rodseth</LastName><ForeName>Reitze N</ForeName><Initials>RN</Initials><AffiliationInfo><Affiliation>University of KwaZulu-Natal, Pietermaritzburg, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buse</LastName><ForeName>Giovanna A Lurati</ForeName><Initials>GAL</Initials><AffiliationInfo><Affiliation>University Hospital Düsseldorf, Düsseldorf, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bhandari</LastName><ForeName>Mohit</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Garutti</LastName><ForeName>Ignacia</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Hospital Universitario Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacka</LastName><ForeName>Michael J</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>University of Alberta, Edmonton, Alberta, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schünemann</LastName><ForeName>Holger J</ForeName><Initials>HJ</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cortes</LastName><ForeName>Olga Lucía</ForeName><Initials>OL</Initials><AffiliationInfo><Affiliation>Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Coriat</LastName><ForeName>Pierre</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Universite Pierre et Marie Curie, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dvirnik</LastName><ForeName>Nazari</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Botto</LastName><ForeName>Fernando</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Hospital Universitario Austral, Pilar, Buenos Aires, Argentina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pettit</LastName><ForeName>Shirley</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jaffe</LastName><ForeName>Allan S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Mayo Clinic, Rochester, Minnesota.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guyatt</LastName><ForeName>Gordon H</ForeName><Initials>GH</Initials><AffiliationInfo><Affiliation>McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>JAMA</MedlineTA><NlmUniqueID>7501160</NlmUniqueID><ISSNLinking>0098-7484</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D020107">Troponin T</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>JAMA. 2017 Sep 5;318(9):864-865</RefSource><PMID Version="1">28873154</PMID></CommentsCorrections><CommentsCorrections RefType="CommentIn"><RefSource>J Thorac Dis. 2017 Aug;9(8):2231-2234</RefSource><PMID Version="1">28932512</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009203" MajorTopicYN="N">Myocardial Infarction</DescriptorName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017202" MajorTopicYN="N">Myocardial Ischemia</DescriptorName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011183" MajorTopicYN="N">Postoperative Complications</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011184" MajorTopicYN="N">Postoperative Period</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018570" MajorTopicYN="N">Risk Assessment</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020107" MajorTopicYN="N">Troponin T</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>7</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28444280</ArticleId><ArticleId IdType="pii">2620089</ArticleId><ArticleId 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