Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs).
Identifieur interne : 000830 ( PubMed/Curation ); précédent : 000829; suivant : 000831Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs).
Auteurs : U. Ronellenfitsch [Allemagne] ; M. Schwarzbach [Allemagne] ; R. Hofheinz [Allemagne] ; P. Kienle [Allemagne] ; K. Nowak [Allemagne] ; M. Kieser [Allemagne] ; T E Slanger [Allemagne] ; B. Burmeister [Australie] ; D. Kelsen [États-Unis] ; D. Niedzwiecki [États-Unis] ; C. Schuhmacher [Allemagne] ; S. Urba [États-Unis] ; C. Van De Velde [Pays-Bas] ; T N Walsh [Irlande (pays)] ; M. Ychou [France] ; K. Jensen [Allemagne]Source :
- European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology [ 1532-2157 ] ; 2017.
Descripteurs français
- KwdFr :
- Adénocarcinome (), Adénocarcinome (traitement médicamenteux), Essais contrôlés randomisés comme sujet, Humains, Pronostic, Résultat thérapeutique, Taux de survie, Traitement médicamenteux adjuvant, Traitement néoadjuvant, Tumeurs de l'estomac (), Tumeurs de l'estomac (traitement médicamenteux), Tumeurs de l'oesophage (), Tumeurs de l'oesophage (traitement médicamenteux).
- MESH :
- traitement médicamenteux : Adénocarcinome, Tumeurs de l'estomac, Tumeurs de l'oesophage.
- Adénocarcinome, Essais contrôlés randomisés comme sujet, Humains, Pronostic, Résultat thérapeutique, Taux de survie, Traitement médicamenteux adjuvant, Traitement néoadjuvant, Tumeurs de l'estomac, Tumeurs de l'oesophage.
English descriptors
- KwdEn :
- Adenocarcinoma (drug therapy), Adenocarcinoma (surgery), Chemotherapy, Adjuvant, Esophageal Neoplasms (drug therapy), Esophageal Neoplasms (surgery), Humans, Neoadjuvant Therapy, Prognosis, Randomized Controlled Trials as Topic, Stomach Neoplasms (drug therapy), Stomach Neoplasms (surgery), Survival Rate, Treatment Outcome.
- MESH :
Abstract
Neoadjuvant chemotherapy improves prognosis of patients with locally advanced gastroesophageal adenocarcinoma. The aim of this study was to identify predictors for postoperative survival following neoadjuvant therapy. These could be useful in deciding about postoperative continuation of chemotherapy.
DOI: 10.1016/j.ejso.2017.05.005
PubMed: 28551325
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000833
Links to Exploration step
pubmed:28551325Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs).</title><author><name sortKey="Ronellenfitsch, U" sort="Ronellenfitsch, U" uniqKey="Ronellenfitsch U" first="U" last="Ronellenfitsch">U. Ronellenfitsch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: ulrich.ronellenfitsch@med.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Schwarzbach, M" sort="Schwarzbach, M" uniqKey="Schwarzbach M" first="M" last="Schwarzbach">M. Schwarzbach</name><affiliation wicri:level="1"><nlm:affiliation>Department of General, Visceral, Vascular, and Thoracic Surgery, Klinikum Frankfurt Höchst, Gotenstraße 6-8, 65929 Frankfurt am Main, Germany. Electronic address: matthias.schwarzbach@klinikumfrankfurt.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of General, Visceral, Vascular, and Thoracic Surgery, Klinikum Frankfurt Höchst, Gotenstraße 6-8, 65929 Frankfurt am Main</wicri:regionArea></affiliation></author><author><name sortKey="Hofheinz, R" sort="Hofheinz, R" uniqKey="Hofheinz R" first="R" last="Hofheinz">R. Hofheinz</name><affiliation wicri:level="1"><nlm:affiliation>Day Treatment Center (TTZ), Interdisciplinary Tumor Center Mannheim (ITM) & 3rd Department of Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: ralf.hofheinz@umm.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Day Treatment Center (TTZ), Interdisciplinary Tumor Center Mannheim (ITM) & 3rd Department of Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Kienle, P" sort="Kienle, P" uniqKey="Kienle P" first="P" last="Kienle">P. Kienle</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: peter.kienle@umm.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Nowak, K" sort="Nowak, K" uniqKey="Nowak K" first="K" last="Nowak">K. Nowak</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: kai.nowak@umm.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Kieser, M" sort="Kieser, M" uniqKey="Kieser M" first="M" last="Kieser">M. Kieser</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg, Germany. Electronic address: kieser@imbi.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Slanger, T E" sort="Slanger, T E" uniqKey="Slanger T" first="T E" last="Slanger">T E Slanger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: t.slanger@hotmail.com.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Burmeister, B" sort="Burmeister, B" uniqKey="Burmeister B" first="B" last="Burmeister">B. Burmeister</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia. Electronic address: Bryan.Burmeister@health.qld.gov.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland, Princess Alexandra Hospital, Brisbane, QLD 4102</wicri:regionArea></affiliation></author><author><name sortKey="Kelsen, D" sort="Kelsen, D" uniqKey="Kelsen D" first="D" last="Kelsen">D. Kelsen</name><affiliation wicri:level="1"><nlm:affiliation>Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10021, USA. Electronic address: kelsend@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10021</wicri:regionArea></affiliation></author><author><name sortKey="Niedzwiecki, D" sort="Niedzwiecki, D" uniqKey="Niedzwiecki D" first="D" last="Niedzwiecki">D. Niedzwiecki</name><affiliation wicri:level="1"><nlm:affiliation>The Alliance for Clinical Trials in Oncology (Alliance) Statistics and Data Center, Duke University Medical Center, Hock Plaza, 2424 Erwin Rd, Room 8040, Durham, NC 27705, USA. Electronic address: donna.niedzwiecki@duke.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Alliance for Clinical Trials in Oncology (Alliance) Statistics and Data Center, Duke University Medical Center, Hock Plaza, 2424 Erwin Rd, Room 8040, Durham, NC 27705</wicri:regionArea></affiliation></author><author><name sortKey="Schuhmacher, C" sort="Schuhmacher, C" uniqKey="Schuhmacher C" first="C" last="Schuhmacher">C. Schuhmacher</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Klinikum rechts der Isar, Technical University Munich, Ismaninger Str. 22, 81675 Munich, Germany. Electronic address: christoph.schuhmacher@tum.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, Klinikum rechts der Isar, Technical University Munich, Ismaninger Str. 22, 81675 Munich</wicri:regionArea></affiliation></author><author><name sortKey="Urba, S" sort="Urba, S" uniqKey="Urba S" first="S" last="Urba">S. Urba</name><affiliation wicri:level="1"><nlm:affiliation>Division of Hematology/Oncology, University of Michigan Medical Center, 1500 E Medical Center Drive, C347, SPC 5848, Ann Arbor, MI 48109, USA. Electronic address: surba@med.umich.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Hematology/Oncology, University of Michigan Medical Center, 1500 E Medical Center Drive, C347, SPC 5848, Ann Arbor, MI 48109</wicri:regionArea></affiliation></author><author><name sortKey="Van De Velde, C" sort="Van De Velde, C" uniqKey="Van De Velde C" first="C" last="Van De Velde">C. Van De Velde</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Leiden University Medical Center, K6-R, P.O. Box 9600, 2300 RC Leiden, The Netherlands. Electronic address: c.j.h.van_de_velde@lumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, Leiden University Medical Center, K6-R, P.O. Box 9600, 2300 RC Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Walsh, T N" sort="Walsh, T N" uniqKey="Walsh T" first="T N" last="Walsh">T N Walsh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Connolly Hospital, Blanchardstown, Dublin 15, Ireland. Electronic address: proftnwalsh@gmail.com.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Surgery, Connolly Hospital, Blanchardstown, Dublin 15</wicri:regionArea></affiliation></author><author><name sortKey="Ychou, M" sort="Ychou, M" uniqKey="Ychou M" first="M" last="Ychou">M. Ychou</name><affiliation wicri:level="1"><nlm:affiliation>Centre Régional de Lutte Contre le Cancer, Val d'Aurelle, Montpellier Cedex 05, France. Electronic address: marc.ychou@icm.unicancer.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Régional de Lutte Contre le Cancer, Val d'Aurelle, Montpellier Cedex 05</wicri:regionArea></affiliation></author><author><name sortKey="Jensen, K" sort="Jensen, K" uniqKey="Jensen K" first="K" last="Jensen">K. Jensen</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg, Germany. Electronic address: jensen@imbi.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28551325</idno><idno type="pmid">28551325</idno><idno type="doi">10.1016/j.ejso.2017.05.005</idno><idno type="wicri:Area/PubMed/Corpus">000833</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000833</idno><idno type="wicri:Area/PubMed/Curation">000830</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000830</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs).</title><author><name sortKey="Ronellenfitsch, U" sort="Ronellenfitsch, U" uniqKey="Ronellenfitsch U" first="U" last="Ronellenfitsch">U. Ronellenfitsch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: ulrich.ronellenfitsch@med.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Schwarzbach, M" sort="Schwarzbach, M" uniqKey="Schwarzbach M" first="M" last="Schwarzbach">M. Schwarzbach</name><affiliation wicri:level="1"><nlm:affiliation>Department of General, Visceral, Vascular, and Thoracic Surgery, Klinikum Frankfurt Höchst, Gotenstraße 6-8, 65929 Frankfurt am Main, Germany. Electronic address: matthias.schwarzbach@klinikumfrankfurt.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of General, Visceral, Vascular, and Thoracic Surgery, Klinikum Frankfurt Höchst, Gotenstraße 6-8, 65929 Frankfurt am Main</wicri:regionArea></affiliation></author><author><name sortKey="Hofheinz, R" sort="Hofheinz, R" uniqKey="Hofheinz R" first="R" last="Hofheinz">R. Hofheinz</name><affiliation wicri:level="1"><nlm:affiliation>Day Treatment Center (TTZ), Interdisciplinary Tumor Center Mannheim (ITM) & 3rd Department of Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: ralf.hofheinz@umm.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Day Treatment Center (TTZ), Interdisciplinary Tumor Center Mannheim (ITM) & 3rd Department of Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Kienle, P" sort="Kienle, P" uniqKey="Kienle P" first="P" last="Kienle">P. Kienle</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: peter.kienle@umm.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Nowak, K" sort="Nowak, K" uniqKey="Nowak K" first="K" last="Nowak">K. Nowak</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: kai.nowak@umm.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Kieser, M" sort="Kieser, M" uniqKey="Kieser M" first="M" last="Kieser">M. Kieser</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg, Germany. Electronic address: kieser@imbi.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Slanger, T E" sort="Slanger, T E" uniqKey="Slanger T" first="T E" last="Slanger">T E Slanger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: t.slanger@hotmail.com.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim</wicri:regionArea></affiliation></author><author><name sortKey="Burmeister, B" sort="Burmeister, B" uniqKey="Burmeister B" first="B" last="Burmeister">B. Burmeister</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia. Electronic address: Bryan.Burmeister@health.qld.gov.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland, Princess Alexandra Hospital, Brisbane, QLD 4102</wicri:regionArea></affiliation></author><author><name sortKey="Kelsen, D" sort="Kelsen, D" uniqKey="Kelsen D" first="D" last="Kelsen">D. Kelsen</name><affiliation wicri:level="1"><nlm:affiliation>Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10021, USA. Electronic address: kelsend@mskcc.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10021</wicri:regionArea></affiliation></author><author><name sortKey="Niedzwiecki, D" sort="Niedzwiecki, D" uniqKey="Niedzwiecki D" first="D" last="Niedzwiecki">D. Niedzwiecki</name><affiliation wicri:level="1"><nlm:affiliation>The Alliance for Clinical Trials in Oncology (Alliance) Statistics and Data Center, Duke University Medical Center, Hock Plaza, 2424 Erwin Rd, Room 8040, Durham, NC 27705, USA. Electronic address: donna.niedzwiecki@duke.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Alliance for Clinical Trials in Oncology (Alliance) Statistics and Data Center, Duke University Medical Center, Hock Plaza, 2424 Erwin Rd, Room 8040, Durham, NC 27705</wicri:regionArea></affiliation></author><author><name sortKey="Schuhmacher, C" sort="Schuhmacher, C" uniqKey="Schuhmacher C" first="C" last="Schuhmacher">C. Schuhmacher</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Klinikum rechts der Isar, Technical University Munich, Ismaninger Str. 22, 81675 Munich, Germany. Electronic address: christoph.schuhmacher@tum.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Surgery, Klinikum rechts der Isar, Technical University Munich, Ismaninger Str. 22, 81675 Munich</wicri:regionArea></affiliation></author><author><name sortKey="Urba, S" sort="Urba, S" uniqKey="Urba S" first="S" last="Urba">S. Urba</name><affiliation wicri:level="1"><nlm:affiliation>Division of Hematology/Oncology, University of Michigan Medical Center, 1500 E Medical Center Drive, C347, SPC 5848, Ann Arbor, MI 48109, USA. Electronic address: surba@med.umich.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Hematology/Oncology, University of Michigan Medical Center, 1500 E Medical Center Drive, C347, SPC 5848, Ann Arbor, MI 48109</wicri:regionArea></affiliation></author><author><name sortKey="Van De Velde, C" sort="Van De Velde, C" uniqKey="Van De Velde C" first="C" last="Van De Velde">C. Van De Velde</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Leiden University Medical Center, K6-R, P.O. Box 9600, 2300 RC Leiden, The Netherlands. Electronic address: c.j.h.van_de_velde@lumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, Leiden University Medical Center, K6-R, P.O. Box 9600, 2300 RC Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Walsh, T N" sort="Walsh, T N" uniqKey="Walsh T" first="T N" last="Walsh">T N Walsh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Connolly Hospital, Blanchardstown, Dublin 15, Ireland. Electronic address: proftnwalsh@gmail.com.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Surgery, Connolly Hospital, Blanchardstown, Dublin 15</wicri:regionArea></affiliation></author><author><name sortKey="Ychou, M" sort="Ychou, M" uniqKey="Ychou M" first="M" last="Ychou">M. Ychou</name><affiliation wicri:level="1"><nlm:affiliation>Centre Régional de Lutte Contre le Cancer, Val d'Aurelle, Montpellier Cedex 05, France. Electronic address: marc.ychou@icm.unicancer.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Régional de Lutte Contre le Cancer, Val d'Aurelle, Montpellier Cedex 05</wicri:regionArea></affiliation></author><author><name sortKey="Jensen, K" sort="Jensen, K" uniqKey="Jensen K" first="K" last="Jensen">K. Jensen</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg, Germany. Electronic address: jensen@imbi.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg</wicri:regionArea></affiliation></author></analytic><series><title level="j">European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology</title><idno type="eISSN">1532-2157</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenocarcinoma (drug therapy)</term><term>Adenocarcinoma (surgery)</term><term>Chemotherapy, Adjuvant</term><term>Esophageal Neoplasms (drug therapy)</term><term>Esophageal Neoplasms (surgery)</term><term>Humans</term><term>Neoadjuvant Therapy</term><term>Prognosis</term><term>Randomized Controlled Trials as Topic</term><term>Stomach Neoplasms (drug therapy)</term><term>Stomach Neoplasms (surgery)</term><term>Survival Rate</term><term>Treatment Outcome</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adénocarcinome ()</term><term>Adénocarcinome (traitement médicamenteux)</term><term>Essais contrôlés randomisés comme sujet</term><term>Humains</term><term>Pronostic</term><term>Résultat thérapeutique</term><term>Taux de survie</term><term>Traitement médicamenteux adjuvant</term><term>Traitement néoadjuvant</term><term>Tumeurs de l'estomac ()</term><term>Tumeurs de l'estomac (traitement médicamenteux)</term><term>Tumeurs de l'oesophage ()</term><term>Tumeurs de l'oesophage (traitement médicamenteux)</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Adenocarcinoma</term><term>Esophageal Neoplasms</term><term>Stomach Neoplasms</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Adenocarcinoma</term><term>Esophageal Neoplasms</term><term>Stomach Neoplasms</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Adénocarcinome</term><term>Tumeurs de l'estomac</term><term>Tumeurs de l'oesophage</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Chemotherapy, Adjuvant</term><term>Humans</term><term>Neoadjuvant Therapy</term><term>Prognosis</term><term>Randomized Controlled Trials as Topic</term><term>Survival Rate</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adénocarcinome</term><term>Essais contrôlés randomisés comme sujet</term><term>Humains</term><term>Pronostic</term><term>Résultat thérapeutique</term><term>Taux de survie</term><term>Traitement médicamenteux adjuvant</term><term>Traitement néoadjuvant</term><term>Tumeurs de l'estomac</term><term>Tumeurs de l'oesophage</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Neoadjuvant chemotherapy improves prognosis of patients with locally advanced gastroesophageal adenocarcinoma. The aim of this study was to identify predictors for postoperative survival following neoadjuvant therapy. These could be useful in deciding about postoperative continuation of chemotherapy.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28551325</PMID><DateCreated><Year>2017</Year><Month>05</Month><Day>28</Day></DateCreated><DateCompleted><Year>2017</Year><Month>09</Month><Day>05</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>06</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-2157</ISSN><JournalIssue CitedMedium="Internet"><Volume>43</Volume><Issue>8</Issue><PubDate><Year>2017</Year><Month>Aug</Month></PubDate></JournalIssue><Title>European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology</Title><ISOAbbreviation>Eur J Surg Oncol</ISOAbbreviation></Journal><ArticleTitle>Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs).</ArticleTitle><Pagination><MedlinePgn>1550-1558</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0748-7983(17)30482-1</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ejso.2017.05.005</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Neoadjuvant chemotherapy improves prognosis of patients with locally advanced gastroesophageal adenocarcinoma. The aim of this study was to identify predictors for postoperative survival following neoadjuvant therapy. These could be useful in deciding about postoperative continuation of chemotherapy.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">This meta-analysis used IPD from RCTs comparing neoadjuvant chemotherapy with surgery alone for gastroesophageal adenocarcinoma. Trials providing IPD on age, sex, performance status, pT/N stage, resection status, overall and recurrence-free survival were included. Survival was calculated in the entire study population and subgroups stratified by supposed predictors and compared using the log-rank test. Multivariable Cox models were used to identify independent survival predictors.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Four RCTs providing IPD from 553 patients fulfilled the inclusion criteria. (y)pT and (y)pN stage and resection status strongly predicted postoperative survival both after neoadjuvant therapy and surgery alone. Patients with R1 resection after neoadjuvant therapy survived longer than those with R1 resection after surgery alone. Patients with stage pN0 after surgery alone had better prognosis than those with ypN0 after neoadjuvant therapy. Patients with stage ypT3/4 after neoadjuvant therapy survived longer than those with stage pT3/4 after surgery alone. Multivariable regression identified resection status and (y)pN stage as predictors of survival in both groups. (y)pT stage predicted survival only after surgery alone.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">After neoadjuvant therapy for gastroesophageal adenocarcinoma, survival is determined by the same factors as after surgery alone. However, ypT stage is not an independent predictor. These results can facilitate the decision about postoperative continuation of chemotherapy in pretreated patients.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ronellenfitsch</LastName><ForeName>U</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: ulrich.ronellenfitsch@med.uni-heidelberg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schwarzbach</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of General, Visceral, Vascular, and Thoracic Surgery, Klinikum Frankfurt Höchst, Gotenstraße 6-8, 65929 Frankfurt am Main, Germany. Electronic address: matthias.schwarzbach@klinikumfrankfurt.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hofheinz</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Day Treatment Center (TTZ), Interdisciplinary Tumor Center Mannheim (ITM) & 3rd Department of Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: ralf.hofheinz@umm.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kienle</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: peter.kienle@umm.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nowak</LastName><ForeName>K</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: kai.nowak@umm.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kieser</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg, Germany. Electronic address: kieser@imbi.uni-heidelberg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Slanger</LastName><ForeName>T E</ForeName><Initials>TE</Initials><AffiliationInfo><Affiliation>Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Electronic address: t.slanger@hotmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Burmeister</LastName><ForeName>B</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>University of Queensland, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia. Electronic address: Bryan.Burmeister@health.qld.gov.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kelsen</LastName><ForeName>D</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10021, USA. Electronic address: kelsend@mskcc.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Niedzwiecki</LastName><ForeName>D</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>The Alliance for Clinical Trials in Oncology (Alliance) Statistics and Data Center, Duke University Medical Center, Hock Plaza, 2424 Erwin Rd, Room 8040, Durham, NC 27705, USA. Electronic address: donna.niedzwiecki@duke.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schuhmacher</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Surgery, Klinikum rechts der Isar, Technical University Munich, Ismaninger Str. 22, 81675 Munich, Germany. Electronic address: christoph.schuhmacher@tum.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Urba</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Division of Hematology/Oncology, University of Michigan Medical Center, 1500 E Medical Center Drive, C347, SPC 5848, Ann Arbor, MI 48109, USA. Electronic address: surba@med.umich.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van de Velde</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Surgery, Leiden University Medical Center, K6-R, P.O. Box 9600, 2300 RC Leiden, The Netherlands. Electronic address: c.j.h.van_de_velde@lumc.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walsh</LastName><ForeName>T N</ForeName><Initials>TN</Initials><AffiliationInfo><Affiliation>Department of Surgery, Connolly Hospital, Blanchardstown, Dublin 15, Ireland. Electronic address: proftnwalsh@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ychou</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Centre Régional de Lutte Contre le Cancer, Val d'Aurelle, Montpellier Cedex 05, France. Electronic address: marc.ychou@icm.unicancer.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jensen</LastName><ForeName>K</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130, 69120 Heidelberg, Germany. Electronic address: jensen@imbi.uni-heidelberg.de.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>05</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Eur J Surg Oncol</MedlineTA><NlmUniqueID>8504356</NlmUniqueID><ISSNLinking>0748-7983</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000230" MajorTopicYN="N">Adenocarcinoma</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017024" MajorTopicYN="Y">Chemotherapy, Adjuvant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004938" MajorTopicYN="N">Esophageal Neoplasms</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020360" MajorTopicYN="Y">Neoadjuvant Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016032" MajorTopicYN="N">Randomized Controlled Trials as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013274" MajorTopicYN="N">Stomach Neoplasms</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015996" MajorTopicYN="N">Survival Rate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Esophageal cancer</Keyword><Keyword MajorTopicYN="N">Individual patient data meta-analysis</Keyword><Keyword MajorTopicYN="N">Preoperative chemoradiotherapy</Keyword><Keyword MajorTopicYN="N">Preoperative chemotherapy</Keyword><Keyword MajorTopicYN="N">Stomach cancer</Keyword><Keyword MajorTopicYN="N">Survival</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>03</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>05</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>5</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>5</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28551325</ArticleId><ArticleId IdType="pii">S0748-7983(17)30482-1</ArticleId><ArticleId IdType="doi">10.1016/j.ejso.2017.05.005</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000830 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000830 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:28551325
|texte= Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs).
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:28551325" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |