Patient-specific blood pressure correction technique for arterial stiffness: evaluation in a cohort on anti-angiogenic medication.
Identifieur interne : 000748 ( PubMed/Curation ); précédent : 000747; suivant : 000749Patient-specific blood pressure correction technique for arterial stiffness: evaluation in a cohort on anti-angiogenic medication.
Auteurs : Bart Spronck [Pays-Bas] ; Tammo Delhaas [Pays-Bas] ; Anouk Gw De Lepper [Pays-Bas] ; Julie Giroux [France] ; François Goldwasser [France] ; Pierre Boutouyrie [France] ; Maureen Alivon [France] ; Koen D. Reesink [Pays-Bas]Source :
- Hypertension research : official journal of the Japanese Society of Hypertension [ 1348-4214 ] ; 2017.
Abstract
Arterial pulse wave velocity (PWV) depends on blood pressure (BP). Correction of PWV for BP is commonly performed using a statistical approach, requiring a patient cohort. We recently developed a mechanistic, model-predictive approach to assess BP-independent changes in carotid PWV (cPWV) at the level of the individual. The goal of the present study is to compare our novel technique to conventional statistical correction, in the context of anti-cancer therapy using anti-angiogenic drugs (AADs). AADs frequently lead to a PWV increase, but also to hypertension, underlining the need for BP correction of PWV measurements. We obtained carotid artery systolic and diastolic cross-sectional areas (echotracking) and corresponding BPs (tonometry) in 48 patients before starting AAD treatment (sorafenib/sunitinib), and at four follow-up visits spaced 2 weeks apart. For each patient, we derived cPWV and a baseline single-exponential BP cross-sectional area curve. Based on these baseline curves and follow-up BPs, we predicted cPWV at follow-up due to BP. By comparing predicted and measured cPWVs at follow-up, we assessed the BP-independent cPWV increase. In the same way, we assessed whether diastolic cross-sectional area (Ad) changed beyond the BP-induced amount. The AAD-induced BP-independent increase in cPWV was 0.43(0.09,0.77) m s(-1) (mean (95%CI), P=0.014, mechanistic approach) and 0.48(0.14,0.82) m s(-1) (P=0.006, statistical approach). Ad increased with 1.92(0.93,2.92) mm(2) (P<0.001) and 2.14(1.06,3.23) mm(2) (P<0.001), respectively. In conclusion, the present study demonstrates the feasibility and potential of our mechanistic, model-predictive approach to quantify BP-independent effects on arterial stiffness at the level of the individual, in a clinically relevant setting of AAD therapy.
DOI: 10.1038/hr.2017.32
PubMed: 28298652
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000751
Links to Exploration step
pubmed:28298652Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Patient-specific blood pressure correction technique for arterial stiffness: evaluation in a cohort on anti-angiogenic medication.</title><author><name sortKey="Spronck, Bart" sort="Spronck, Bart" uniqKey="Spronck B" first="Bart" last="Spronck">Bart Spronck</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht</wicri:regionArea></affiliation></author><author><name sortKey="Delhaas, Tammo" sort="Delhaas, Tammo" uniqKey="Delhaas T" first="Tammo" last="Delhaas">Tammo Delhaas</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht</wicri:regionArea></affiliation></author><author><name sortKey="De Lepper, Anouk Gw" sort="De Lepper, Anouk Gw" uniqKey="De Lepper A" first="Anouk Gw" last="De Lepper">Anouk Gw De Lepper</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht</wicri:regionArea></affiliation></author><author><name sortKey="Giroux, Julie" sort="Giroux, Julie" uniqKey="Giroux J" first="Julie" last="Giroux">Julie Giroux</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Goldwasser, Francois" sort="Goldwasser, Francois" uniqKey="Goldwasser F" first="François" last="Goldwasser">François Goldwasser</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Boutouyrie, Pierre" sort="Boutouyrie, Pierre" uniqKey="Boutouyrie P" first="Pierre" last="Boutouyrie">Pierre Boutouyrie</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Alivon, Maureen" sort="Alivon, Maureen" uniqKey="Alivon M" first="Maureen" last="Alivon">Maureen Alivon</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Reesink, Koen D" sort="Reesink, Koen D" uniqKey="Reesink K" first="Koen D" last="Reesink">Koen D. Reesink</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28298652</idno><idno type="pmid">28298652</idno><idno type="doi">10.1038/hr.2017.32</idno><idno type="wicri:Area/PubMed/Corpus">000751</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000751</idno><idno type="wicri:Area/PubMed/Curation">000748</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000748</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Patient-specific blood pressure correction technique for arterial stiffness: evaluation in a cohort on anti-angiogenic medication.</title><author><name sortKey="Spronck, Bart" sort="Spronck, Bart" uniqKey="Spronck B" first="Bart" last="Spronck">Bart Spronck</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht</wicri:regionArea></affiliation></author><author><name sortKey="Delhaas, Tammo" sort="Delhaas, Tammo" uniqKey="Delhaas T" first="Tammo" last="Delhaas">Tammo Delhaas</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht</wicri:regionArea></affiliation></author><author><name sortKey="De Lepper, Anouk Gw" sort="De Lepper, Anouk Gw" uniqKey="De Lepper A" first="Anouk Gw" last="De Lepper">Anouk Gw De Lepper</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht</wicri:regionArea></affiliation></author><author><name sortKey="Giroux, Julie" sort="Giroux, Julie" uniqKey="Giroux J" first="Julie" last="Giroux">Julie Giroux</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Goldwasser, Francois" sort="Goldwasser, Francois" uniqKey="Goldwasser F" first="François" last="Goldwasser">François Goldwasser</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Boutouyrie, Pierre" sort="Boutouyrie, Pierre" uniqKey="Boutouyrie P" first="Pierre" last="Boutouyrie">Pierre Boutouyrie</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Alivon, Maureen" sort="Alivon, Maureen" uniqKey="Alivon M" first="Maureen" last="Alivon">Maureen Alivon</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Reesink, Koen D" sort="Reesink, Koen D" uniqKey="Reesink K" first="Koen D" last="Reesink">Koen D. Reesink</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht</wicri:regionArea></affiliation></author></analytic><series><title level="j">Hypertension research : official journal of the Japanese Society of Hypertension</title><idno type="eISSN">1348-4214</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Arterial pulse wave velocity (PWV) depends on blood pressure (BP). Correction of PWV for BP is commonly performed using a statistical approach, requiring a patient cohort. We recently developed a mechanistic, model-predictive approach to assess BP-independent changes in carotid PWV (cPWV) at the level of the individual. The goal of the present study is to compare our novel technique to conventional statistical correction, in the context of anti-cancer therapy using anti-angiogenic drugs (AADs). AADs frequently lead to a PWV increase, but also to hypertension, underlining the need for BP correction of PWV measurements. We obtained carotid artery systolic and diastolic cross-sectional areas (echotracking) and corresponding BPs (tonometry) in 48 patients before starting AAD treatment (sorafenib/sunitinib), and at four follow-up visits spaced 2 weeks apart. For each patient, we derived cPWV and a baseline single-exponential BP cross-sectional area curve. Based on these baseline curves and follow-up BPs, we predicted cPWV at follow-up due to BP. By comparing predicted and measured cPWVs at follow-up, we assessed the BP-independent cPWV increase. In the same way, we assessed whether diastolic cross-sectional area (Ad) changed beyond the BP-induced amount. The AAD-induced BP-independent increase in cPWV was 0.43(0.09,0.77) m s(-1) (mean (95%CI), P=0.014, mechanistic approach) and 0.48(0.14,0.82) m s(-1) (P=0.006, statistical approach). Ad increased with 1.92(0.93,2.92) mm(2) (P<0.001) and 2.14(1.06,3.23) mm(2) (P<0.001), respectively. In conclusion, the present study demonstrates the feasibility and potential of our mechanistic, model-predictive approach to quantify BP-independent effects on arterial stiffness at the level of the individual, in a clinically relevant setting of AAD therapy.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28298652</PMID><DateCreated><Year>2017</Year><Month>03</Month><Day>16</Day></DateCreated><DateRevised><Year>2017</Year><Month>08</Month><Day>08</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1348-4214</ISSN><JournalIssue CitedMedium="Internet"><Volume>40</Volume><Issue>8</Issue><PubDate><Year>2017</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Hypertension research : official journal of the Japanese Society of Hypertension</Title><ISOAbbreviation>Hypertens. Res.</ISOAbbreviation></Journal><ArticleTitle>Patient-specific blood pressure correction technique for arterial stiffness: evaluation in a cohort on anti-angiogenic medication.</ArticleTitle><Pagination><MedlinePgn>752-757</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/hr.2017.32</ELocationID><Abstract><AbstractText>Arterial pulse wave velocity (PWV) depends on blood pressure (BP). Correction of PWV for BP is commonly performed using a statistical approach, requiring a patient cohort. We recently developed a mechanistic, model-predictive approach to assess BP-independent changes in carotid PWV (cPWV) at the level of the individual. The goal of the present study is to compare our novel technique to conventional statistical correction, in the context of anti-cancer therapy using anti-angiogenic drugs (AADs). AADs frequently lead to a PWV increase, but also to hypertension, underlining the need for BP correction of PWV measurements. We obtained carotid artery systolic and diastolic cross-sectional areas (echotracking) and corresponding BPs (tonometry) in 48 patients before starting AAD treatment (sorafenib/sunitinib), and at four follow-up visits spaced 2 weeks apart. For each patient, we derived cPWV and a baseline single-exponential BP cross-sectional area curve. Based on these baseline curves and follow-up BPs, we predicted cPWV at follow-up due to BP. By comparing predicted and measured cPWVs at follow-up, we assessed the BP-independent cPWV increase. In the same way, we assessed whether diastolic cross-sectional area (Ad) changed beyond the BP-induced amount. The AAD-induced BP-independent increase in cPWV was 0.43(0.09,0.77) m s(-1) (mean (95%CI), P=0.014, mechanistic approach) and 0.48(0.14,0.82) m s(-1) (P=0.006, statistical approach). Ad increased with 1.92(0.93,2.92) mm(2) (P<0.001) and 2.14(1.06,3.23) mm(2) (P<0.001), respectively. In conclusion, the present study demonstrates the feasibility and potential of our mechanistic, model-predictive approach to quantify BP-independent effects on arterial stiffness at the level of the individual, in a clinically relevant setting of AAD therapy.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Spronck</LastName><ForeName>Bart</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Delhaas</LastName><ForeName>Tammo</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Lepper</LastName><ForeName>Anouk Gw</ForeName><Initials>AG</Initials><AffiliationInfo><Affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Giroux</LastName><ForeName>Julie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goldwasser</LastName><ForeName>François</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, CERIA, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boutouyrie</LastName><ForeName>Pierre</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alivon</LastName><ForeName>Maureen</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Pharmacology, Université Paris Descartes, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Reesink</LastName><ForeName>Koen D</ForeName><Initials>KD</Initials><AffiliationInfo><Affiliation>Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>03</Month><Day>16</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Hypertens Res</MedlineTA><NlmUniqueID>9307690</NlmUniqueID><ISSNLinking>0916-9636</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Ultrasound Med Biol. 2004 Feb;30(2):147-54</RefSource><PMID Version="1">14998666</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Oncol. 2008 Feb;9(2):117-23</RefSource><PMID Version="1">18221915</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ophthalmology. 2009 Sep;116(9):1755-61</RefSource><PMID Version="1">19560206</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Hypertens. 2015 Feb;33(2):330-8</RefSource><PMID Version="1">25380150</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Cardiothorac Surg. 2016 May;49(5):1403-10</RefSource><PMID Version="1">26464453</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Circulation. 1995 May 15;91(10):2669-78</RefSource><PMID Version="1">7743631</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Hypertens Res. 2016 Jan;39(1):27-38</RefSource><PMID Version="1">26490088</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Hypertens Res. 2015 Jan;38(1):68-73</RefSource><PMID Version="1">25231254</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Hypertens. 2015 Jun;33(6):1310-7</RefSource><PMID Version="1">25715093</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sci Transl Med. 2010 Jan 20;2(15):15ps3</RefSource><PMID Version="1">20371469</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Hypertens. 2016 Mar;29(3):299-302</RefSource><PMID Version="1">25968122</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Hypertens. 2001 Jun;19(6):1037-44</RefSource><PMID Version="1">11403351</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Hypertens. 2017 Jan;35(1):98-104</RefSource><PMID Version="1">27906838</PMID></CommentsCorrections></CommentsCorrectionsList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>11</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>01</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>02</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>3</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>3</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>3</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28298652</ArticleId><ArticleId IdType="pii">hr201732</ArticleId><ArticleId IdType="doi">10.1038/hr.2017.32</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000748 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000748 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:28298652
|texte= Patient-specific blood pressure correction technique for arterial stiffness: evaluation in a cohort on anti-angiogenic medication.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:28298652" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |