Soft-tissue infection secondary to cellulitis killed St. John of the Cross (1542-1591).
Identifieur interne : 000331 ( PubMed/Curation ); précédent : 000330; suivant : 000332Soft-tissue infection secondary to cellulitis killed St. John of the Cross (1542-1591).
Auteurs : Raffaella Bianucci [Italie] ; Otto Appenzeller [États-Unis] ; Peter Evans [Australie] ; Philippe Charlier [France] ; Antonio Perciaccante [Italie]Source :
- Infection [ 1439-0973 ] ; 2017.
Abstract
St. John of the Cross (1542-1591) died aged 49 years after 3 months of excruciating pain following a trivial lesion in his right foot. Erysipelas, a superficial bacterial infection of the skin, and subsequent sepsis were previously suggested as the cause of his death. Here, an alternative diagnosis is proposed.
DOI: 10.1007/s15010-017-1089-x
PubMed: 29090420
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Enhancement and Marathon Clinics Research Foundation, 361 Big Horn Ridge Dr. NE, Albuquerque, NM, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New Mexico Health Enhancement and Marathon Clinics Research Foundation, 361 Big Horn Ridge Dr. NE, Albuquerque, NM</wicri:regionArea></affiliation></author><author><name sortKey="Evans, Peter" sort="Evans, Peter" uniqKey="Evans P" first="Peter" last="Evans">Peter Evans</name><affiliation wicri:level="1"><nlm:affiliation>, Unit 1, 26 Windsor Cres Surrey Hills, Melbourne, VIC, 3127, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>, Unit 1, 26 Windsor Cres Surrey Hills, Melbourne, VIC, 3127</wicri:regionArea></affiliation></author><author><name sortKey="Charlier, Philippe" sort="Charlier, Philippe" uniqKey="Charlier P" first="Philippe" last="Charlier">Philippe Charlier</name><affiliation wicri:level="1"><nlm:affiliation>Section of Medical and Forensic Anthropology (UVSQ DANTE Laboratory EA4498), 2 avenue de la Source de la Bièvre, 78180, Montigny-Le-Bretonneux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Section of Medical and Forensic Anthropology (UVSQ DANTE Laboratory EA4498), 2 avenue de la Source de la Bièvre, 78180, Montigny-Le-Bretonneux</wicri:regionArea></affiliation></author><author><name sortKey="Perciaccante, Antonio" sort="Perciaccante, Antonio" uniqKey="Perciaccante A" first="Antonio" last="Perciaccante">Antonio Perciaccante</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, "San Giovanni di Dio" Hospital, Gorizia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medicine, "San Giovanni di Dio" Hospital, Gorizia</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:29090420</idno><idno type="pmid">29090420</idno><idno 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Health and Paediatric Sciences, University of Turin, C.so Galileo Galilei 22, 10126, Turin</wicri:regionArea></affiliation></author><author><name sortKey="Appenzeller, Otto" sort="Appenzeller, Otto" uniqKey="Appenzeller O" first="Otto" last="Appenzeller">Otto Appenzeller</name><affiliation wicri:level="1"><nlm:affiliation>New Mexico Health Enhancement and Marathon Clinics Research Foundation, 361 Big Horn Ridge Dr. NE, Albuquerque, NM, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New Mexico Health Enhancement and Marathon Clinics Research Foundation, 361 Big Horn Ridge Dr. NE, Albuquerque, NM</wicri:regionArea></affiliation></author><author><name sortKey="Evans, Peter" sort="Evans, Peter" uniqKey="Evans P" first="Peter" last="Evans">Peter Evans</name><affiliation wicri:level="1"><nlm:affiliation>, Unit 1, 26 Windsor Cres Surrey Hills, Melbourne, VIC, 3127, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>, Unit 1, 26 Windsor Cres Surrey Hills, Melbourne, VIC, 3127</wicri:regionArea></affiliation></author><author><name sortKey="Charlier, Philippe" sort="Charlier, Philippe" uniqKey="Charlier P" first="Philippe" last="Charlier">Philippe Charlier</name><affiliation wicri:level="1"><nlm:affiliation>Section of Medical and Forensic Anthropology (UVSQ DANTE Laboratory EA4498), 2 avenue de la Source de la Bièvre, 78180, Montigny-Le-Bretonneux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Section of Medical and Forensic Anthropology (UVSQ DANTE Laboratory EA4498), 2 avenue de la Source de la Bièvre, 78180, Montigny-Le-Bretonneux</wicri:regionArea></affiliation></author><author><name sortKey="Perciaccante, Antonio" sort="Perciaccante, Antonio" uniqKey="Perciaccante A" first="Antonio" last="Perciaccante">Antonio Perciaccante</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, "San Giovanni di Dio" Hospital, Gorizia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medicine, "San Giovanni di Dio" Hospital, Gorizia</wicri:regionArea></affiliation></author></analytic><series><title level="j">Infection</title><idno type="eISSN">1439-0973</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">St. John of the Cross (1542-1591) died aged 49 years after 3 months of excruciating pain following a trivial lesion in his right foot. Erysipelas, a superficial bacterial infection of the skin, and subsequent sepsis were previously suggested as the cause of his death. Here, an alternative diagnosis is proposed.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">29090420</PMID><DateCreated><Year>2017</Year><Month>11</Month><Day>01</Day></DateCreated><DateRevised><Year>2017</Year><Month>11</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1439-0973</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2017</Year><Month>Oct</Month><Day>31</Day></PubDate></JournalIssue><Title>Infection</Title><ISOAbbreviation>Infection</ISOAbbreviation></Journal><ArticleTitle>Soft-tissue infection secondary to cellulitis killed St. John of the Cross (1542-1591).</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1007/s15010-017-1089-x</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">St. John of the Cross (1542-1591) died aged 49 years after 3 months of excruciating pain following a trivial lesion in his right foot. Erysipelas, a superficial bacterial infection of the skin, and subsequent sepsis were previously suggested as the cause of his death. Here, an alternative diagnosis is proposed.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">An accurate perusal of his biography allowed the symptomatology, the clinical evolution, the depth of the infection and the associated systemic manifestations displayed by Fray John to be reconstructed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">St. John of the Cross developed cellulitis in the foot, which turned into a cutaneous abscess. To treat the toxaemia and inhibit further necrosis of the skin, excision of necrotic tissue and cauterization of the sores were performed to no avail. The infection burrowed through the fascial planes and reached the bones of the leg, leading to osteomyelitis.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In the absence of antibiotic treatments and proper antiseptic procedures, the soft-tissue infection spread deeper to the bones. It is not unconceivable that the surgery might have further promoted the spread of the bacteria giving rise to the secondary sepsis that led to St. John's premature death.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bianucci</LastName><ForeName>Raffaella</ForeName><Initials>R</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-2740-4112</Identifier><AffiliationInfo><Affiliation>Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, C.so Galileo Galilei 22, 10126, Turin, Italy. raffaella.bianucci@unito.it.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Warwick Medical School, Microbiology and Infection Division, University of Warwick, Coventry, UK. raffaella.bianucci@unito.it.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>UMR 7268, Laboratoire d'Anthropologie bio-culturelle, Droit, Etique and Santé (Adés), Faculté de Médecine de Marseille, Marseille, France. raffaella.bianucci@unito.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Appenzeller</LastName><ForeName>Otto</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>New Mexico Health Enhancement and Marathon Clinics Research Foundation, 361 Big Horn Ridge Dr. NE, Albuquerque, NM, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>New Mexico Museum of Natural History and Science, 1801 Mountain Road NW, Albuquerque, NM, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>, Unit 1, 26 Windsor Cres Surrey Hills, Melbourne, VIC, 3127, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Charlier</LastName><ForeName>Philippe</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Section of Medical and Forensic Anthropology (UVSQ DANTE Laboratory EA4498), 2 avenue de la Source de la Bièvre, 78180, Montigny-Le-Bretonneux, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>CASH and IPES, 403 avenue de la République, 92000, Nanterre, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perciaccante</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, "San Giovanni di Dio" Hospital, Gorizia, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>10</Month><Day>31</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Infection</MedlineTA><NlmUniqueID>0365307</NlmUniqueID><ISSNLinking>0300-8126</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Cellulitis</Keyword><Keyword MajorTopicYN="N">Cutaneous abscess</Keyword><Keyword MajorTopicYN="N">Septicaemia</Keyword><Keyword MajorTopicYN="N">Soft-tissue</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>08</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>10</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>11</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>11</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>11</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29090420</ArticleId><ArticleId IdType="doi">10.1007/s15010-017-1089-x</ArticleId><ArticleId IdType="pii">10.1007/s15010-017-1089-x</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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