Common variants at 12q15 and 12q24 are associated with infant head circumference.
Identifieur interne : 003B75 ( PubMed/Corpus ); précédent : 003B74; suivant : 003B76Common variants at 12q15 and 12q24 are associated with infant head circumference.
Auteurs : H Rob Taal ; Beate St Pourcain ; Elisabeth Thiering ; Shikta Das ; Dennis O. Mook-Kanamori ; Nicole M. Warrington ; Marika Kaakinen ; Eskil Kreiner-M Ller ; Jonathan P. Bradfield ; Rachel M. Freathy ; Frank Geller ; M Nica Guxens ; Diana L. Cousminer ; Marjan Kerkhof ; Nicholas J. Timpson ; M Arfan Ikram ; Lawrence J. Beilin ; Klaus B Nnelykke ; Jessica L. Buxton ; Pimphen Charoen ; Bo Lund Krogsgaard Chawes ; Johan Eriksson ; David M. Evans ; Albert Hofman ; John P. Kemp ; Cecilia E. Kim ; Norman Klopp ; Jari Lahti ; Stephen J. Lye ; George Mcmahon ; Frank D. Mentch ; Martina Müller ; Paul F. O'Reilly ; Inga Prokopenko ; Fernando Rivadeneira ; Eric A P. Steegers ; Jordi Sunyer ; Carla Tiesler ; Hanieh Yaghootkar ; Monique M B. Breteler ; Stephanie Debette ; Myriam Fornage ; Vilmundur Gudnason ; Lenore J. Launer ; Aad Van Der Lugt ; Thomas H. Mosley ; Sudha Seshadri ; Albert V. Smith ; Meike W. Vernooij ; Alexandra If Blakemore ; Rosetta M. Chiavacci ; Bjarke Feenstra ; Julio Fernandez-Benet ; Struan F A. Grant ; Anna-Liisa Hartikainen ; Albert J. Van Der Heijden ; Carmen I Iguez ; Mark Lathrop ; Wendy L. Mcardle ; Anne M Lgaard ; John P. Newnham ; Lyle J. Palmer ; Aarno Palotie ; Annneli Pouta ; Susan M. Ring ; Ulla Sovio ; Marie Standl ; Andre G. Uitterlinden ; H-Erich Wichmann ; Nadja Hawwa Vissing ; Charles Decarli ; Cornelia M. Van Duijn ; Mark I. Mccarthy ; Gerard H. Koppelman ; Xavier Estivill ; Andrew T. Hattersley ; Mads Melbye ; Hans Bisgaard ; Craig E. Pennell ; Elisabeth Widen ; Hakon Hakonarson ; George Davey Smith ; Joachim Heinrich ; Marjo-Riitta Jarvelin ; Vincent W V. JaddoeSource :
- Nature genetics [ 1546-1718 ] ; 2012.
English descriptors
- KwdEn :
- Chromosomes, Human, Pair 12 (genetics), European Continental Ancestry Group (genetics), Female, Genetic Loci, Genetic Markers, Genome-Wide Association Study, Head (growth & development), Head (pathology), Humans, Infant, Male, Meta-Analysis as Topic, Polymorphism, Single Nucleotide (genetics), Pregnancy, Pregnancy Complications (etiology), Pregnancy Complications (pathology).
- MESH :
- chemical : Genetic Markers.
- etiology : Pregnancy Complications.
- genetics : Chromosomes, Human, Pair 12, European Continental Ancestry Group, Polymorphism, Single Nucleotide.
- growth & development : Head.
- pathology : Head, Pregnancy Complications.
- Female, Genetic Loci, Genome-Wide Association Study, Humans, Infant, Male, Meta-Analysis as Topic, Pregnancy.
Abstract
To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 × 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 × 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height, their effects on infant head circumference were largely independent of height (P = 3.8 × 10(-7) for rs7980687 and P = 1.3 × 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 × 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume, Parkinson's disease and other neurodegenerative diseases, indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.
DOI: 10.1038/ng.2238
PubMed: 22504419
Links to Exploration step
pubmed:22504419Le document en format XML
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<author><name sortKey="Taal, H Rob" sort="Taal, H Rob" uniqKey="Taal H" first="H Rob" last="Taal">H Rob Taal</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
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<author><name sortKey="Pourcain, Beate St" sort="Pourcain, Beate St" uniqKey="Pourcain B" first="Beate St" last="Pourcain">Beate St Pourcain</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
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<author><name sortKey="Thiering, Elisabeth" sort="Thiering, Elisabeth" uniqKey="Thiering E" first="Elisabeth" last="Thiering">Elisabeth Thiering</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
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<author><name sortKey="Das, Shikta" sort="Das, Shikta" uniqKey="Das S" first="Shikta" last="Das">Shikta Das</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</nlm:affiliation>
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<author><name sortKey="Mook Kanamori, Dennis O" sort="Mook Kanamori, Dennis O" uniqKey="Mook Kanamori D" first="Dennis O" last="Mook-Kanamori">Dennis O. Mook-Kanamori</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
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<author><name sortKey="Warrington, Nicole M" sort="Warrington, Nicole M" uniqKey="Warrington N" first="Nicole M" last="Warrington">Nicole M. Warrington</name>
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<author><name sortKey="Kaakinen, Marika" sort="Kaakinen, Marika" uniqKey="Kaakinen M" first="Marika" last="Kaakinen">Marika Kaakinen</name>
<affiliation><nlm:affiliation>Institute of Health Sciences, University of Oulu, Finland.</nlm:affiliation>
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<author><name sortKey="Kreiner M Ller, Eskil" sort="Kreiner M Ller, Eskil" uniqKey="Kreiner M Ller E" first="Eskil" last="Kreiner-M Ller">Eskil Kreiner-M Ller</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
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<author><name sortKey="Bradfield, Jonathan P" sort="Bradfield, Jonathan P" uniqKey="Bradfield J" first="Jonathan P" last="Bradfield">Jonathan P. Bradfield</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
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<author><name sortKey="Freathy, Rachel M" sort="Freathy, Rachel M" uniqKey="Freathy R" first="Rachel M" last="Freathy">Rachel M. Freathy</name>
<affiliation><nlm:affiliation>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.</nlm:affiliation>
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<author><name sortKey="Geller, Frank" sort="Geller, Frank" uniqKey="Geller F" first="Frank" last="Geller">Frank Geller</name>
<affiliation><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Guxens, M Nica" sort="Guxens, M Nica" uniqKey="Guxens M" first="M Nica" last="Guxens">M Nica Guxens</name>
<affiliation><nlm:affiliation>Center for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain.</nlm:affiliation>
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<author><name sortKey="Cousminer, Diana L" sort="Cousminer, Diana L" uniqKey="Cousminer D" first="Diana L" last="Cousminer">Diana L. Cousminer</name>
<affiliation><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
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<author><name sortKey="Kerkhof, Marjan" sort="Kerkhof, Marjan" uniqKey="Kerkhof M" first="Marjan" last="Kerkhof">Marjan Kerkhof</name>
<affiliation><nlm:affiliation>Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Timpson, Nicholas J" sort="Timpson, Nicholas J" uniqKey="Timpson N" first="Nicholas J" last="Timpson">Nicholas J. Timpson</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Beilin, Lawrence J" sort="Beilin, Lawrence J" uniqKey="Beilin L" first="Lawrence J" last="Beilin">Lawrence J. Beilin</name>
<affiliation><nlm:affiliation>School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="B Nnelykke, Klaus" sort="B Nnelykke, Klaus" uniqKey="B Nnelykke K" first="Klaus" last="B Nnelykke">Klaus B Nnelykke</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Buxton, Jessica L" sort="Buxton, Jessica L" uniqKey="Buxton J" first="Jessica L" last="Buxton">Jessica L. Buxton</name>
<affiliation><nlm:affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Charoen, Pimphen" sort="Charoen, Pimphen" uniqKey="Charoen P" first="Pimphen" last="Charoen">Pimphen Charoen</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chawes, Bo Lund Krogsgaard" sort="Chawes, Bo Lund Krogsgaard" uniqKey="Chawes B" first="Bo Lund Krogsgaard" last="Chawes">Bo Lund Krogsgaard Chawes</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Eriksson, Johan" sort="Eriksson, Johan" uniqKey="Eriksson J" first="Johan" last="Eriksson">Johan Eriksson</name>
<affiliation><nlm:affiliation>National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Evans, David M" sort="Evans, David M" uniqKey="Evans D" first="David M" last="Evans">David M. Evans</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kemp, John P" sort="Kemp, John P" uniqKey="Kemp J" first="John P" last="Kemp">John P. Kemp</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kim, Cecilia E" sort="Kim, Cecilia E" uniqKey="Kim C" first="Cecilia E" last="Kim">Cecilia E. Kim</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Klopp, Norman" sort="Klopp, Norman" uniqKey="Klopp N" first="Norman" last="Klopp">Norman Klopp</name>
<affiliation><nlm:affiliation>Research Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name>
<affiliation><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lye, Stephen J" sort="Lye, Stephen J" uniqKey="Lye S" first="Stephen J" last="Lye">Stephen J. Lye</name>
<affiliation><nlm:affiliation>Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mcmahon, George" sort="Mcmahon, George" uniqKey="Mcmahon G" first="George" last="Mcmahon">George Mcmahon</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mentch, Frank D" sort="Mentch, Frank D" uniqKey="Mentch F" first="Frank D" last="Mentch">Frank D. Mentch</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Muller, Martina" sort="Muller, Martina" uniqKey="Muller M" first="Martina" last="Müller">Martina Müller</name>
<affiliation><nlm:affiliation>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="O Reilly, Paul F" sort="O Reilly, Paul F" uniqKey="O Reilly P" first="Paul F" last="O'Reilly">Paul F. O'Reilly</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, W2 1PG London, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name>
<affiliation><nlm:affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Steegers, Eric A P" sort="Steegers, Eric A P" uniqKey="Steegers E" first="Eric A P" last="Steegers">Eric A P. Steegers</name>
<affiliation><nlm:affiliation>Department of Obstetrics & Gynecology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sunyer, Jordi" sort="Sunyer, Jordi" uniqKey="Sunyer J" first="Jordi" last="Sunyer">Jordi Sunyer</name>
<affiliation><nlm:affiliation>Center for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tiesler, Carla" sort="Tiesler, Carla" uniqKey="Tiesler C" first="Carla" last="Tiesler">Carla Tiesler</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Yaghootkar, Hanieh" sort="Yaghootkar, Hanieh" uniqKey="Yaghootkar H" first="Hanieh" last="Yaghootkar">Hanieh Yaghootkar</name>
<affiliation><nlm:affiliation>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Breteler, Monique M B" sort="Breteler, Monique M B" uniqKey="Breteler M" first="Monique M B" last="Breteler">Monique M B. Breteler</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stephanie" last="Debette">Stephanie Debette</name>
<affiliation><nlm:affiliation>Department of Neurology, Boston University School of Medicine, Boston, MA, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name>
<affiliation><nlm:affiliation>Institute of Molecular Medicine, Human Genetics Center and Division of Epidemiology, School of Public Health, University of Texas, Houston Health Sciences Center, Houston, TX, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name>
<affiliation><nlm:affiliation>Icelandic Heart Association, Kopavogus, Iceland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name>
<affiliation><nlm:affiliation>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institute of Health, Bethesda, MD, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Der Lugt, Aad" sort="Van Der Lugt, Aad" uniqKey="Van Der Lugt A" first="Aad" last="Van Der Lugt">Aad Van Der Lugt</name>
<affiliation><nlm:affiliation>Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H" last="Mosley">Thomas H. Mosley</name>
<affiliation><nlm:affiliation>Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, MS, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Seshadri, Sudha" sort="Seshadri, Sudha" uniqKey="Seshadri S" first="Sudha" last="Seshadri">Sudha Seshadri</name>
<affiliation><nlm:affiliation>Department of Neurology, Boston University School of Medicine, Boston, MA, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name>
<affiliation><nlm:affiliation>Icelandic Heart Association, Kopavogus, Iceland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vernooij, Meike W" sort="Vernooij, Meike W" uniqKey="Vernooij M" first="Meike W" last="Vernooij">Meike W. Vernooij</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Blakemore, Alexandra If" sort="Blakemore, Alexandra If" uniqKey="Blakemore A" first="Alexandra If" last="Blakemore">Alexandra If Blakemore</name>
<affiliation><nlm:affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chiavacci, Rosetta M" sort="Chiavacci, Rosetta M" uniqKey="Chiavacci R" first="Rosetta M" last="Chiavacci">Rosetta M. Chiavacci</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Feenstra, Bjarke" sort="Feenstra, Bjarke" uniqKey="Feenstra B" first="Bjarke" last="Feenstra">Bjarke Feenstra</name>
<affiliation><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fernandez Benet, Julio" sort="Fernandez Benet, Julio" uniqKey="Fernandez Benet J" first="Julio" last="Fernandez-Benet">Julio Fernandez-Benet</name>
<affiliation><nlm:affiliation>European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Grant, Struan F A" sort="Grant, Struan F A" uniqKey="Grant S" first="Struan F A" last="Grant">Struan F A. Grant</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hartikainen, Anna Liisa" sort="Hartikainen, Anna Liisa" uniqKey="Hartikainen A" first="Anna-Liisa" last="Hartikainen">Anna-Liisa Hartikainen</name>
<affiliation><nlm:affiliation>Institute of Clinical Medicine/Obstetrics and Gynecology, University of Oulu, Oulu, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Der Heijden, Albert J" sort="Van Der Heijden, Albert J" uniqKey="Van Der Heijden A" first="Albert J" last="Van Der Heijden">Albert J. Van Der Heijden</name>
<affiliation><nlm:affiliation>Department of Paediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="I Iguez, Carmen" sort="I Iguez, Carmen" uniqKey="I Iguez C" first="Carmen" last="I Iguez">Carmen I Iguez</name>
<affiliation><nlm:affiliation>CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Catalonia, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name>
<affiliation><nlm:affiliation>Centre National de Génotypage, Evry, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name>
<affiliation><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="M Lgaard, Anne" sort="M Lgaard, Anne" uniqKey="M Lgaard A" first="Anne" last="M Lgaard">Anne M Lgaard</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Newnham, John P" sort="Newnham, John P" uniqKey="Newnham J" first="John P" last="Newnham">John P. Newnham</name>
<affiliation><nlm:affiliation>School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name>
<affiliation><nlm:affiliation>Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<affiliation><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pouta, Annneli" sort="Pouta, Annneli" uniqKey="Pouta A" first="Annneli" last="Pouta">Annneli Pouta</name>
<affiliation><nlm:affiliation>National Institute for Health and Welfare, Oulu, Finland, Biocenter Oulu, University of Oulu, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ring, Susan M" sort="Ring, Susan M" uniqKey="Ring S" first="Susan M" last="Ring">Susan M. Ring</name>
<affiliation><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sovio, Ulla" sort="Sovio, Ulla" uniqKey="Sovio U" first="Ulla" last="Sovio">Ulla Sovio</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Standl, Marie" sort="Standl, Marie" uniqKey="Standl M" first="Marie" last="Standl">Marie Standl</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vissing, Nadja Hawwa" sort="Vissing, Nadja Hawwa" uniqKey="Vissing N" first="Nadja Hawwa" last="Vissing">Nadja Hawwa Vissing</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Decarli, Charles" sort="Decarli, Charles" uniqKey="Decarli C" first="Charles" last="Decarli">Charles Decarli</name>
<affiliation><nlm:affiliation>Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, CA, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name>
<affiliation><nlm:affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Koppelman, Gerard H" sort="Koppelman, Gerard H" uniqKey="Koppelman G" first="Gerard H" last="Koppelman">Gerard H. Koppelman</name>
<affiliation><nlm:affiliation>Department of Pediatric Pulmonology and Pediatric Allergology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Estivill, Xavier" sort="Estivill, Xavier" uniqKey="Estivill X" first="Xavier" last="Estivill">Xavier Estivill</name>
<affiliation><nlm:affiliation>CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Catalonia, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T" last="Hattersley">Andrew T. Hattersley</name>
<affiliation><nlm:affiliation>Peninsula NIHR Clinical Research Facility, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name>
<affiliation><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bisgaard, Hans" sort="Bisgaard, Hans" uniqKey="Bisgaard H" first="Hans" last="Bisgaard">Hans Bisgaard</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pennell, Craig E" sort="Pennell, Craig E" uniqKey="Pennell C" first="Craig E" last="Pennell">Craig E. Pennell</name>
<affiliation><nlm:affiliation>School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Widen, Elisabeth" sort="Widen, Elisabeth" uniqKey="Widen E" first="Elisabeth" last="Widen">Elisabeth Widen</name>
<affiliation><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Smith, George Davey" sort="Smith, George Davey" uniqKey="Smith G" first="George Davey" last="Smith">George Davey Smith</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Heinrich, Joachim" sort="Heinrich, Joachim" uniqKey="Heinrich J" first="Joachim" last="Heinrich">Joachim Heinrich</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name>
<affiliation><nlm:affiliation>Institute of Health Sciences, University of Oulu, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jaddoe, Vincent W V" sort="Jaddoe, Vincent W V" uniqKey="Jaddoe V" first="Vincent W V" last="Jaddoe">Vincent W V. Jaddoe</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2012">2012</date>
<idno type="RBID">pubmed:22504419</idno>
<idno type="pmid">22504419</idno>
<idno type="doi">10.1038/ng.2238</idno>
<idno type="wicri:Area/PubMed/Corpus">003B75</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003B75</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Common variants at 12q15 and 12q24 are associated with infant head circumference.</title>
<author><name sortKey="Taal, H Rob" sort="Taal, H Rob" uniqKey="Taal H" first="H Rob" last="Taal">H Rob Taal</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pourcain, Beate St" sort="Pourcain, Beate St" uniqKey="Pourcain B" first="Beate St" last="Pourcain">Beate St Pourcain</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Thiering, Elisabeth" sort="Thiering, Elisabeth" uniqKey="Thiering E" first="Elisabeth" last="Thiering">Elisabeth Thiering</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Das, Shikta" sort="Das, Shikta" uniqKey="Das S" first="Shikta" last="Das">Shikta Das</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mook Kanamori, Dennis O" sort="Mook Kanamori, Dennis O" uniqKey="Mook Kanamori D" first="Dennis O" last="Mook-Kanamori">Dennis O. Mook-Kanamori</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Warrington, Nicole M" sort="Warrington, Nicole M" uniqKey="Warrington N" first="Nicole M" last="Warrington">Nicole M. Warrington</name>
<affiliation><nlm:affiliation>School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kaakinen, Marika" sort="Kaakinen, Marika" uniqKey="Kaakinen M" first="Marika" last="Kaakinen">Marika Kaakinen</name>
<affiliation><nlm:affiliation>Institute of Health Sciences, University of Oulu, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kreiner M Ller, Eskil" sort="Kreiner M Ller, Eskil" uniqKey="Kreiner M Ller E" first="Eskil" last="Kreiner-M Ller">Eskil Kreiner-M Ller</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bradfield, Jonathan P" sort="Bradfield, Jonathan P" uniqKey="Bradfield J" first="Jonathan P" last="Bradfield">Jonathan P. Bradfield</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Freathy, Rachel M" sort="Freathy, Rachel M" uniqKey="Freathy R" first="Rachel M" last="Freathy">Rachel M. Freathy</name>
<affiliation><nlm:affiliation>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Geller, Frank" sort="Geller, Frank" uniqKey="Geller F" first="Frank" last="Geller">Frank Geller</name>
<affiliation><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Guxens, M Nica" sort="Guxens, M Nica" uniqKey="Guxens M" first="M Nica" last="Guxens">M Nica Guxens</name>
<affiliation><nlm:affiliation>Center for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cousminer, Diana L" sort="Cousminer, Diana L" uniqKey="Cousminer D" first="Diana L" last="Cousminer">Diana L. Cousminer</name>
<affiliation><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kerkhof, Marjan" sort="Kerkhof, Marjan" uniqKey="Kerkhof M" first="Marjan" last="Kerkhof">Marjan Kerkhof</name>
<affiliation><nlm:affiliation>Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Timpson, Nicholas J" sort="Timpson, Nicholas J" uniqKey="Timpson N" first="Nicholas J" last="Timpson">Nicholas J. Timpson</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Beilin, Lawrence J" sort="Beilin, Lawrence J" uniqKey="Beilin L" first="Lawrence J" last="Beilin">Lawrence J. Beilin</name>
<affiliation><nlm:affiliation>School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="B Nnelykke, Klaus" sort="B Nnelykke, Klaus" uniqKey="B Nnelykke K" first="Klaus" last="B Nnelykke">Klaus B Nnelykke</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Buxton, Jessica L" sort="Buxton, Jessica L" uniqKey="Buxton J" first="Jessica L" last="Buxton">Jessica L. Buxton</name>
<affiliation><nlm:affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Charoen, Pimphen" sort="Charoen, Pimphen" uniqKey="Charoen P" first="Pimphen" last="Charoen">Pimphen Charoen</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chawes, Bo Lund Krogsgaard" sort="Chawes, Bo Lund Krogsgaard" uniqKey="Chawes B" first="Bo Lund Krogsgaard" last="Chawes">Bo Lund Krogsgaard Chawes</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Eriksson, Johan" sort="Eriksson, Johan" uniqKey="Eriksson J" first="Johan" last="Eriksson">Johan Eriksson</name>
<affiliation><nlm:affiliation>National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Evans, David M" sort="Evans, David M" uniqKey="Evans D" first="David M" last="Evans">David M. Evans</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kemp, John P" sort="Kemp, John P" uniqKey="Kemp J" first="John P" last="Kemp">John P. Kemp</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kim, Cecilia E" sort="Kim, Cecilia E" uniqKey="Kim C" first="Cecilia E" last="Kim">Cecilia E. Kim</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Klopp, Norman" sort="Klopp, Norman" uniqKey="Klopp N" first="Norman" last="Klopp">Norman Klopp</name>
<affiliation><nlm:affiliation>Research Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name>
<affiliation><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lye, Stephen J" sort="Lye, Stephen J" uniqKey="Lye S" first="Stephen J" last="Lye">Stephen J. Lye</name>
<affiliation><nlm:affiliation>Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mcmahon, George" sort="Mcmahon, George" uniqKey="Mcmahon G" first="George" last="Mcmahon">George Mcmahon</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mentch, Frank D" sort="Mentch, Frank D" uniqKey="Mentch F" first="Frank D" last="Mentch">Frank D. Mentch</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Muller, Martina" sort="Muller, Martina" uniqKey="Muller M" first="Martina" last="Müller">Martina Müller</name>
<affiliation><nlm:affiliation>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="O Reilly, Paul F" sort="O Reilly, Paul F" uniqKey="O Reilly P" first="Paul F" last="O'Reilly">Paul F. O'Reilly</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, W2 1PG London, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name>
<affiliation><nlm:affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Steegers, Eric A P" sort="Steegers, Eric A P" uniqKey="Steegers E" first="Eric A P" last="Steegers">Eric A P. Steegers</name>
<affiliation><nlm:affiliation>Department of Obstetrics & Gynecology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sunyer, Jordi" sort="Sunyer, Jordi" uniqKey="Sunyer J" first="Jordi" last="Sunyer">Jordi Sunyer</name>
<affiliation><nlm:affiliation>Center for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tiesler, Carla" sort="Tiesler, Carla" uniqKey="Tiesler C" first="Carla" last="Tiesler">Carla Tiesler</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Yaghootkar, Hanieh" sort="Yaghootkar, Hanieh" uniqKey="Yaghootkar H" first="Hanieh" last="Yaghootkar">Hanieh Yaghootkar</name>
<affiliation><nlm:affiliation>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Breteler, Monique M B" sort="Breteler, Monique M B" uniqKey="Breteler M" first="Monique M B" last="Breteler">Monique M B. Breteler</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stephanie" last="Debette">Stephanie Debette</name>
<affiliation><nlm:affiliation>Department of Neurology, Boston University School of Medicine, Boston, MA, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name>
<affiliation><nlm:affiliation>Institute of Molecular Medicine, Human Genetics Center and Division of Epidemiology, School of Public Health, University of Texas, Houston Health Sciences Center, Houston, TX, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name>
<affiliation><nlm:affiliation>Icelandic Heart Association, Kopavogus, Iceland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name>
<affiliation><nlm:affiliation>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institute of Health, Bethesda, MD, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Der Lugt, Aad" sort="Van Der Lugt, Aad" uniqKey="Van Der Lugt A" first="Aad" last="Van Der Lugt">Aad Van Der Lugt</name>
<affiliation><nlm:affiliation>Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H" last="Mosley">Thomas H. Mosley</name>
<affiliation><nlm:affiliation>Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, MS, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Seshadri, Sudha" sort="Seshadri, Sudha" uniqKey="Seshadri S" first="Sudha" last="Seshadri">Sudha Seshadri</name>
<affiliation><nlm:affiliation>Department of Neurology, Boston University School of Medicine, Boston, MA, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name>
<affiliation><nlm:affiliation>Icelandic Heart Association, Kopavogus, Iceland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vernooij, Meike W" sort="Vernooij, Meike W" uniqKey="Vernooij M" first="Meike W" last="Vernooij">Meike W. Vernooij</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Blakemore, Alexandra If" sort="Blakemore, Alexandra If" uniqKey="Blakemore A" first="Alexandra If" last="Blakemore">Alexandra If Blakemore</name>
<affiliation><nlm:affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chiavacci, Rosetta M" sort="Chiavacci, Rosetta M" uniqKey="Chiavacci R" first="Rosetta M" last="Chiavacci">Rosetta M. Chiavacci</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Feenstra, Bjarke" sort="Feenstra, Bjarke" uniqKey="Feenstra B" first="Bjarke" last="Feenstra">Bjarke Feenstra</name>
<affiliation><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fernandez Benet, Julio" sort="Fernandez Benet, Julio" uniqKey="Fernandez Benet J" first="Julio" last="Fernandez-Benet">Julio Fernandez-Benet</name>
<affiliation><nlm:affiliation>European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Grant, Struan F A" sort="Grant, Struan F A" uniqKey="Grant S" first="Struan F A" last="Grant">Struan F A. Grant</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hartikainen, Anna Liisa" sort="Hartikainen, Anna Liisa" uniqKey="Hartikainen A" first="Anna-Liisa" last="Hartikainen">Anna-Liisa Hartikainen</name>
<affiliation><nlm:affiliation>Institute of Clinical Medicine/Obstetrics and Gynecology, University of Oulu, Oulu, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Der Heijden, Albert J" sort="Van Der Heijden, Albert J" uniqKey="Van Der Heijden A" first="Albert J" last="Van Der Heijden">Albert J. Van Der Heijden</name>
<affiliation><nlm:affiliation>Department of Paediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="I Iguez, Carmen" sort="I Iguez, Carmen" uniqKey="I Iguez C" first="Carmen" last="I Iguez">Carmen I Iguez</name>
<affiliation><nlm:affiliation>CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Catalonia, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name>
<affiliation><nlm:affiliation>Centre National de Génotypage, Evry, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name>
<affiliation><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="M Lgaard, Anne" sort="M Lgaard, Anne" uniqKey="M Lgaard A" first="Anne" last="M Lgaard">Anne M Lgaard</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Newnham, John P" sort="Newnham, John P" uniqKey="Newnham J" first="John P" last="Newnham">John P. Newnham</name>
<affiliation><nlm:affiliation>School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name>
<affiliation><nlm:affiliation>Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<affiliation><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pouta, Annneli" sort="Pouta, Annneli" uniqKey="Pouta A" first="Annneli" last="Pouta">Annneli Pouta</name>
<affiliation><nlm:affiliation>National Institute for Health and Welfare, Oulu, Finland, Biocenter Oulu, University of Oulu, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ring, Susan M" sort="Ring, Susan M" uniqKey="Ring S" first="Susan M" last="Ring">Susan M. Ring</name>
<affiliation><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sovio, Ulla" sort="Sovio, Ulla" uniqKey="Sovio U" first="Ulla" last="Sovio">Ulla Sovio</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Standl, Marie" sort="Standl, Marie" uniqKey="Standl M" first="Marie" last="Standl">Marie Standl</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vissing, Nadja Hawwa" sort="Vissing, Nadja Hawwa" uniqKey="Vissing N" first="Nadja Hawwa" last="Vissing">Nadja Hawwa Vissing</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Decarli, Charles" sort="Decarli, Charles" uniqKey="Decarli C" first="Charles" last="Decarli">Charles Decarli</name>
<affiliation><nlm:affiliation>Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, CA, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name>
<affiliation><nlm:affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Koppelman, Gerard H" sort="Koppelman, Gerard H" uniqKey="Koppelman G" first="Gerard H" last="Koppelman">Gerard H. Koppelman</name>
<affiliation><nlm:affiliation>Department of Pediatric Pulmonology and Pediatric Allergology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Estivill, Xavier" sort="Estivill, Xavier" uniqKey="Estivill X" first="Xavier" last="Estivill">Xavier Estivill</name>
<affiliation><nlm:affiliation>CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Catalonia, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T" last="Hattersley">Andrew T. Hattersley</name>
<affiliation><nlm:affiliation>Peninsula NIHR Clinical Research Facility, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name>
<affiliation><nlm:affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bisgaard, Hans" sort="Bisgaard, Hans" uniqKey="Bisgaard H" first="Hans" last="Bisgaard">Hans Bisgaard</name>
<affiliation><nlm:affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pennell, Craig E" sort="Pennell, Craig E" uniqKey="Pennell C" first="Craig E" last="Pennell">Craig E. Pennell</name>
<affiliation><nlm:affiliation>School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Widen, Elisabeth" sort="Widen, Elisabeth" uniqKey="Widen E" first="Elisabeth" last="Widen">Elisabeth Widen</name>
<affiliation><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name>
<affiliation><nlm:affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Smith, George Davey" sort="Smith, George Davey" uniqKey="Smith G" first="George Davey" last="Smith">George Davey Smith</name>
<affiliation><nlm:affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Heinrich, Joachim" sort="Heinrich, Joachim" uniqKey="Heinrich J" first="Joachim" last="Heinrich">Joachim Heinrich</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name>
<affiliation><nlm:affiliation>Institute of Health Sciences, University of Oulu, Finland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jaddoe, Vincent W V" sort="Jaddoe, Vincent W V" uniqKey="Jaddoe V" first="Vincent W V" last="Jaddoe">Vincent W V. Jaddoe</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">Nature genetics</title>
<idno type="eISSN">1546-1718</idno>
<imprint><date when="2012" type="published">2012</date>
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<term>European Continental Ancestry Group (genetics)</term>
<term>Female</term>
<term>Genetic Loci</term>
<term>Genetic Markers</term>
<term>Genome-Wide Association Study</term>
<term>Head (growth & development)</term>
<term>Head (pathology)</term>
<term>Humans</term>
<term>Infant</term>
<term>Male</term>
<term>Meta-Analysis as Topic</term>
<term>Polymorphism, Single Nucleotide (genetics)</term>
<term>Pregnancy</term>
<term>Pregnancy Complications (etiology)</term>
<term>Pregnancy Complications (pathology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Genetic Markers</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Pregnancy Complications</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Chromosomes, Human, Pair 12</term>
<term>European Continental Ancestry Group</term>
<term>Polymorphism, Single Nucleotide</term>
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<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Head</term>
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<term>Pregnancy Complications</term>
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<term>Genetic Loci</term>
<term>Genome-Wide Association Study</term>
<term>Humans</term>
<term>Infant</term>
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<front><div type="abstract" xml:lang="en">To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 × 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 × 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height, their effects on infant head circumference were largely independent of height (P = 3.8 × 10(-7) for rs7980687 and P = 1.3 × 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 × 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume, Parkinson's disease and other neurodegenerative diseases, indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22504419</PMID>
<DateCreated><Year>2012</Year>
<Month>04</Month>
<Day>27</Day>
</DateCreated>
<DateCompleted><Year>2012</Year>
<Month>07</Month>
<Day>02</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>11</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1546-1718</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>44</Volume>
<Issue>5</Issue>
<PubDate><Year>2012</Year>
<Month>Apr</Month>
<Day>15</Day>
</PubDate>
</JournalIssue>
<Title>Nature genetics</Title>
<ISOAbbreviation>Nat. Genet.</ISOAbbreviation>
</Journal>
<ArticleTitle>Common variants at 12q15 and 12q24 are associated with infant head circumference.</ArticleTitle>
<Pagination><MedlinePgn>532-538</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/ng.2238</ELocationID>
<Abstract><AbstractText>To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 × 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 × 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height, their effects on infant head circumference were largely independent of height (P = 3.8 × 10(-7) for rs7980687 and P = 1.3 × 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 × 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume, Parkinson's disease and other neurodegenerative diseases, indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y" EqualContrib="Y"><LastName>Taal</LastName>
<ForeName>H Rob</ForeName>
<Initials>HR</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Paediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y" EqualContrib="Y"><LastName>Pourcain</LastName>
<ForeName>Beate St</ForeName>
<Initials>BS</Initials>
<AffiliationInfo><Affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y" EqualContrib="Y"><LastName>Thiering</LastName>
<ForeName>Elisabeth</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y" EqualContrib="Y"><LastName>Das</LastName>
<ForeName>Shikta</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y" EqualContrib="Y"><LastName>Mook-Kanamori</LastName>
<ForeName>Dennis O</ForeName>
<Initials>DO</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Paediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Weill Cornell Medical College - Qatar, Doha, Qatar.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Warrington</LastName>
<ForeName>Nicole M</ForeName>
<Initials>NM</Initials>
<AffiliationInfo><Affiliation>School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kaakinen</LastName>
<ForeName>Marika</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute of Health Sciences, University of Oulu, Finland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Biocenter Oulu, University of Oulu, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kreiner-Møller</LastName>
<ForeName>Eskil</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bradfield</LastName>
<ForeName>Jonathan P</ForeName>
<Initials>JP</Initials>
<AffiliationInfo><Affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Freathy</LastName>
<ForeName>Rachel M</ForeName>
<Initials>RM</Initials>
<AffiliationInfo><Affiliation>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Geller</LastName>
<ForeName>Frank</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guxens</LastName>
<ForeName>Mònica</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Center for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Hospital del Mar Research Institute (IMIM), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cousminer</LastName>
<ForeName>Diana L</ForeName>
<Initials>DL</Initials>
<AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kerkhof</LastName>
<ForeName>Marjan</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Timpson</LastName>
<ForeName>Nicholas J</ForeName>
<Initials>NJ</Initials>
<AffiliationInfo><Affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ikram</LastName>
<ForeName>M Arfan</ForeName>
<Initials>MA</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Beilin</LastName>
<ForeName>Lawrence J</ForeName>
<Initials>LJ</Initials>
<AffiliationInfo><Affiliation>School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bønnelykke</LastName>
<ForeName>Klaus</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Buxton</LastName>
<ForeName>Jessica L</ForeName>
<Initials>JL</Initials>
<AffiliationInfo><Affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Charoen</LastName>
<ForeName>Pimphen</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chawes</LastName>
<ForeName>Bo Lund Krogsgaard</ForeName>
<Initials>BLK</Initials>
<AffiliationInfo><Affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Eriksson</LastName>
<ForeName>Johan</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>National Institute for Health and Welfare, Helsinki, Finland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Folkhalsan Research Centre, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Evans</LastName>
<ForeName>David M</ForeName>
<Initials>DM</Initials>
<AffiliationInfo><Affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hofman</LastName>
<ForeName>Albert</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kemp</LastName>
<ForeName>John P</ForeName>
<Initials>JP</Initials>
<AffiliationInfo><Affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kim</LastName>
<ForeName>Cecilia E</ForeName>
<Initials>CE</Initials>
<AffiliationInfo><Affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Klopp</LastName>
<ForeName>Norman</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Research Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lahti</LastName>
<ForeName>Jari</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lye</LastName>
<ForeName>Stephen J</ForeName>
<Initials>SJ</Initials>
<AffiliationInfo><Affiliation>Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>McMahon</LastName>
<ForeName>George</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mentch</LastName>
<ForeName>Frank D</ForeName>
<Initials>FD</Initials>
<AffiliationInfo><Affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Müller</LastName>
<ForeName>Martina</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>O'Reilly</LastName>
<ForeName>Paul F</ForeName>
<Initials>PF</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, W2 1PG London, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Prokopenko</LastName>
<ForeName>Inga</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rivadeneira</LastName>
<ForeName>Fernando</ForeName>
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</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Steegers</LastName>
<ForeName>Eric A P</ForeName>
<Initials>EAP</Initials>
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</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sunyer</LastName>
<ForeName>Jordi</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Center for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Hospital del Mar Research Institute (IMIM), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Pompeu Fabra University (UPF), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tiesler</LastName>
<ForeName>Carla</ForeName>
<Initials>C</Initials>
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</AffiliationInfo>
<AffiliationInfo><Affiliation>Dr Von Hauner Children's Hospital, Ludwig-Maximilians University Munich, Munich, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yaghootkar</LastName>
<ForeName>Hanieh</ForeName>
<Initials>H</Initials>
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</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE) Consortium</CollectiveName>
</Author>
<Author ValidYN="Y"><LastName>Breteler</LastName>
<ForeName>Monique M B</ForeName>
<Initials>MMB</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Debette</LastName>
<ForeName>Stephanie</ForeName>
<Initials>S</Initials>
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</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fornage</LastName>
<ForeName>Myriam</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute of Molecular Medicine, Human Genetics Center and Division of Epidemiology, School of Public Health, University of Texas, Houston Health Sciences Center, Houston, TX, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gudnason</LastName>
<ForeName>Vilmundur</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Icelandic Heart Association, Kopavogus, Iceland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>University of Iceland, Reykjavik, Iceland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Launer</LastName>
<ForeName>Lenore J</ForeName>
<Initials>LJ</Initials>
<AffiliationInfo><Affiliation>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institute of Health, Bethesda, MD, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>van der Lugt</LastName>
<ForeName>Aad</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mosley</LastName>
<ForeName>Thomas H</ForeName>
<Initials>TH</Initials>
<AffiliationInfo><Affiliation>Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, MS, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Seshadri</LastName>
<ForeName>Sudha</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, Boston University School of Medicine, Boston, MA, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Smith</LastName>
<ForeName>Albert V</ForeName>
<Initials>AV</Initials>
<AffiliationInfo><Affiliation>Icelandic Heart Association, Kopavogus, Iceland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>University of Iceland, Reykjavik, Iceland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vernooij</LastName>
<ForeName>Meike W</ForeName>
<Initials>MW</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
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</Author>
<Author ValidYN="Y"><LastName>Blakemore</LastName>
<ForeName>Alexandra If</ForeName>
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<AffiliationInfo><Affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chiavacci</LastName>
<ForeName>Rosetta M</ForeName>
<Initials>RM</Initials>
<AffiliationInfo><Affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Feenstra</LastName>
<ForeName>Bjarke</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fernandez-Benet</LastName>
<ForeName>Julio</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Grant</LastName>
<ForeName>Struan F A</ForeName>
<Initials>SFA</Initials>
<AffiliationInfo><Affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Pediatrics, University of Pennsylvania, Philadelphia PA 19104, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hartikainen</LastName>
<ForeName>Anna-Liisa</ForeName>
<Initials>AL</Initials>
<AffiliationInfo><Affiliation>Institute of Clinical Medicine/Obstetrics and Gynecology, University of Oulu, Oulu, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>van der Heijden</LastName>
<ForeName>Albert J</ForeName>
<Initials>AJ</Initials>
<AffiliationInfo><Affiliation>Department of Paediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Iñiguez</LastName>
<ForeName>Carmen</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Division of Environment and Health, Center for Public Health Research-CSISP, Valencia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lathrop</LastName>
<ForeName>Mark</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Centre National de Génotypage, Evry, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Foundation Jean Dausset, CEPH, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>McArdle</LastName>
<ForeName>Wendy L</ForeName>
<Initials>WL</Initials>
<AffiliationInfo><Affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mølgaard</LastName>
<ForeName>Anne</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Newnham</LastName>
<ForeName>John P</ForeName>
<Initials>JP</Initials>
<AffiliationInfo><Affiliation>School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Palmer</LastName>
<ForeName>Lyle J</ForeName>
<Initials>LJ</Initials>
<AffiliationInfo><Affiliation>Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Canada.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Palotie</LastName>
<ForeName>Aarno</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Medical Genetics, University of Helsinki, Helsinki, Finland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pouta</LastName>
<ForeName>Annneli</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>National Institute for Health and Welfare, Oulu, Finland, Biocenter Oulu, University of Oulu, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ring</LastName>
<ForeName>Susan M</ForeName>
<Initials>SM</Initials>
<AffiliationInfo><Affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sovio</LastName>
<ForeName>Ulla</ForeName>
<Initials>U</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>London School of Hygiene and Tropical Medicine, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Standl</LastName>
<ForeName>Marie</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Uitterlinden</LastName>
<ForeName>Andre G</ForeName>
<Initials>AG</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wichmann</LastName>
<ForeName>H-Erich</ForeName>
<Initials>HE</Initials>
<AffiliationInfo><Affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vissing</LastName>
<ForeName>Nadja Hawwa</ForeName>
<Initials>NH</Initials>
<AffiliationInfo><Affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>DeCarli</LastName>
<ForeName>Charles</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, CA, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>van Duijn</LastName>
<ForeName>Cornelia M</ForeName>
<Initials>CM</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>McCarthy</LastName>
<ForeName>Mark I</ForeName>
<Initials>MI</Initials>
<AffiliationInfo><Affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Koppelman</LastName>
<ForeName>Gerard H</ForeName>
<Initials>GH</Initials>
<AffiliationInfo><Affiliation>Department of Pediatric Pulmonology and Pediatric Allergology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Estivill</LastName>
<ForeName>Xavier</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Pompeu Fabra University (UPF), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Genes and Disease Program, Center for Genomic Regulation (CRG-UPF), Barcelona, Catalonia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hattersley</LastName>
<ForeName>Andrew T</ForeName>
<Initials>AT</Initials>
<AffiliationInfo><Affiliation>Peninsula NIHR Clinical Research Facility, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Melbye</LastName>
<ForeName>Mads</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bisgaard</LastName>
<ForeName>Hans</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Copenhagen Prospective Studies on Asthma in Childhood, University of Copenhagen, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pennell</LastName>
<ForeName>Craig E</ForeName>
<Initials>CE</Initials>
<AffiliationInfo><Affiliation>School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Widen</LastName>
<ForeName>Elisabeth</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hakonarson</LastName>
<ForeName>Hakon</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Pediatrics, University of Pennsylvania, Philadelphia PA 19104, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Smith</LastName>
<ForeName>George Davey</ForeName>
<Initials>GD</Initials>
<AffiliationInfo><Affiliation>MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Heinrich</LastName>
<ForeName>Joachim</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jarvelin</LastName>
<ForeName>Marjo-Riitta</ForeName>
<Initials>MR</Initials>
<AffiliationInfo><Affiliation>Institute of Health Sciences, University of Oulu, Finland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>National Institute for Health and Welfare, Oulu, Finland, Biocenter Oulu, University of Oulu, Finland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, Imperial College London.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>Early Growth Genetics (EGG) Consortium</CollectiveName>
</Author>
<Author ValidYN="Y"><LastName>Jaddoe</LastName>
<ForeName>Vincent W V</ForeName>
<Initials>VWV</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Paediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
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<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2009 Dec;41(12):1308-12</RefSource>
<PMID Version="1">19915575</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2009 Nov;41(11):1199-206</RefSource>
<PMID Version="1">19801982</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Endocrinology. 2010 Mar;151(3):1221-7</RefSource>
<PMID Version="1">20032050</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Prog Neurobiol. 2010 Mar;90(3):363-83</RefSource>
<PMID Version="1">19931588</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Genet. 2010 May;6(5):e1000952</RefSource>
<PMID Version="1">20485568</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2010;5(5):e10693</RefSource>
<PMID Version="1">20502693</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Alzheimers Dis. 2010;22(4):1065-71</RefSource>
<PMID Version="1">20930301</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nature. 2010 Oct 14;467(7317):832-8</RefSource>
<PMID Version="1">20881960</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Twin Res Hum Genet. 2010 Aug;13(4):370-80</RefSource>
<PMID Version="1">20707707</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2011 Feb 19;377(9766):641-9</RefSource>
<PMID Version="1">21292315</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2012 May;44(5):539-44</RefSource>
<PMID Version="1">22504418</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Pediatr Res. 2000 Mar;47(3):316-23</RefSource>
<PMID Version="1">10709729</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mol Cell Biol. 2000 Sep;20(17):6300-7</RefSource>
<PMID Version="1">10938106</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nutrition. 2000 Nov-Dec;16(11-12):1056-63</RefSource>
<PMID Version="1">11118825</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Biometrics. 1999 Dec;55(4):997-1004</RefSource>
<PMID Version="1">11315092</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>BMJ. 2003 Sep 6;327(7414):557-60</RefSource>
<PMID Version="1">12958120</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nat Rev Cancer. 2003 Oct;3(10):756-67</RefSource>
<PMID Version="1">14570040</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Brain. 2004 Feb;127(Pt 2):321-9</RefSource>
<PMID Version="1">14645144</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 2004 Mar;75(3):478-80</RefSource>
<PMID Version="1">14966169</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Neurochem. 2004 Apr;89(1):179-88</RefSource>
<PMID Version="1">15030402</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Neuropsychologia. 2004;42(8):1118-31</RefSource>
<PMID Version="1">15093150</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Dis Child. 1976 May;130(5):481-7</RefSource>
<PMID Version="1">1274898</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Development. 1993 Oct;119(2):377-95</RefSource>
<PMID Version="1">8287794</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nature. 1995 Aug 31;376(6543):771-4</RefSource>
<PMID Version="1">7651535</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Arch Gen Psychiatry. 1996 Jul;53(7):607-16</RefSource>
<PMID Version="1">8660127</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mol Biol Cell. 1996 Sep;7(9):1455-69</RefSource>
<PMID Version="1">8885239</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2005 Feb;76(2):340-8</RefSource>
<PMID Version="1">15593017</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Epidemiol. 2006 May 1;163(9):829-37</RefSource>
<PMID Version="1">16524956</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trends Mol Med. 2006 Aug;12(8):358-66</RefSource>
<PMID Version="1">16829198</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Pediatrics. 2006 Oct;118(4):1486-92</RefSource>
<PMID Version="1">17015539</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Hum Biol. 2006 Jul-Aug;33(4):415-23</RefSource>
<PMID Version="1">17060066</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mol Cancer Ther. 2007 Feb;6(2):542-51</RefSource>
<PMID Version="1">17308053</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ultrasound Obstet Gynecol. 2008 Apr;31(4):388-96</RefSource>
<PMID Version="1">18348183</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Neurobiol Aging. 2008 Jun;29(6):882-90</RefSource>
<PMID Version="1">17239994</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Biol. 2008 May 6;6(5):e107</RefSource>
<PMID Version="1">18462017</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Med Genet A. 2008 Aug 1;146A(15):2023-37</RefSource>
<PMID Version="1">18629877</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Genet. 2008 Oct;4(10):e1000214</RefSource>
<PMID Version="1">18846210</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Arch Neurol. 2008 Nov;65(11):1473-8</RefSource>
<PMID Version="1">19001166</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Hum Mutat. 2008 Dec;29(12):1373-86</RefSource>
<PMID Version="1">18543312</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2009 Feb;84(2):286-90</RefSource>
<PMID Version="1">19215732</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Circ Cardiovasc Genet. 2009 Feb;2(1):73-80</RefSource>
<PMID Version="1">20031568</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2009 Mar 6;284(10):6021-5</RefSource>
<PMID Version="1">18948254</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Bioinformatics. 2009 Oct 15;25(20):2768-9</RefSource>
<PMID Version="1">19633095</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="ErratumIn"><RefSource>Nat Genet. 2013 June;45(6):713</RefSource>
<Note>Sørensen, Thorkild I A [removed]</Note>
</CommentsCorrections>
</CommentsCorrectionsList>
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