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Genome-wide association study of prostate cancer-specific survival.

Identifieur interne : 002792 ( PubMed/Corpus ); précédent : 002791; suivant : 002793

Genome-wide association study of prostate cancer-specific survival.

Auteurs : Robert Szulkin ; Robert Karlsson ; Thomas Whitington ; Markus Aly ; Henrik Gronberg ; Rosalind A. Eeles ; Douglas F. Easton ; Zsofia Kote-Jarai ; Ali Amin Al Olama ; Sara Benlloch ; Kenneth Muir ; Graham G. Giles ; Melissa C. Southey ; Liesel M. Fitzgerald ; Brian E. Henderson ; Fredrick R. Schumacher ; Christopher A. Haiman ; Csilla Sipeky ; Teuvo L J. Tammela ; B Rge G. Nordestgaard ; Timothy J. Key ; Ruth C. Travis ; David E. Neal ; Jenny L. Donovan ; Freddie C. Hamdy ; Paul D P. Pharoah ; Nora Pashayan ; Kay-Tee Khaw ; Janet L. Stanford ; Stephen N. Thibodeau ; Shannon K. Mcdonnell ; Daniel J. Schaid ; Christiane Maier ; Walther Vogel ; Manuel Luedeke ; Kathleen Herkommer ; Adam S. Kibel ; Cezary Cybulski ; Jan Lubi Ski ; Wojciech Klu Niak ; Lisa Cannon-Albright ; Hermann Brenner ; Volker Herrmann ; Bernd Holleczek ; Jong Y. Park ; Thomas A. Sellers ; Hui-Yi Lim ; Chavdar Slavov ; Radka P. Kaneva ; Vanio I. Mitev ; Amanda Spurdle ; Manuel R. Teixeira ; Paula Paulo ; Sofia Maia ; Hardev Pandha ; Agnieszka Michael ; Andrzej Kierzek ; Jyotsna Batra ; Judith A. Clements ; Demetrius Albanes ; Gerald L. Andriole ; Sonja I. Berndt ; Stephen Chanock ; Susan M. Gapstur ; Edward L. Giovannucci ; David J. Hunter ; Peter Kraft ; Loic Le Marchand ; Jing Ma ; Alison M. Mondul ; Kathryn L. Penney ; Meir J. Stampfer ; Victoria L. Stevens ; Stephanie J. Weinstein ; Antonia Trichopoulou ; Bas H. Bueno-De-Mesquita ; Anne Tj Nneland ; David G. Cox ; Lovise Maehle ; Johanna Schleutker ; Sara Lindström ; Fredrik Wiklund

Source :

RBID : pubmed:26307654

English descriptors

Abstract

Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical.

DOI: 10.1158/1055-9965.EPI-15-0543
PubMed: 26307654

Links to Exploration step

pubmed:26307654

Le document en format XML

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<nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden. Academic Primary Healthcare Center, Stockholm County Council, Karolinska Institute, Stockholm, Sweden. robert.szulkin@ki.se.</nlm:affiliation>
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<name sortKey="Fitzgerald, Liesel M" sort="Fitzgerald, Liesel M" uniqKey="Fitzgerald L" first="Liesel M" last="Fitzgerald">Liesel M. Fitzgerald</name>
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<name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E" last="Henderson">Brian E. Henderson</name>
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<name sortKey="Sipeky, Csilla" sort="Sipeky, Csilla" uniqKey="Sipeky C" first="Csilla" last="Sipeky">Csilla Sipeky</name>
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<nlm:affiliation>Department of Medical Biochemistry and Genetics, Institute of Biomedicine Kiinamyllynkatu 10, University of Turku, Turku, Finland.</nlm:affiliation>
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<name sortKey="Tammela, Teuvo L J" sort="Tammela, Teuvo L J" uniqKey="Tammela T" first="Teuvo L J" last="Tammela">Teuvo L J. Tammela</name>
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<nlm:affiliation>Department of Urology, Tampere University Hospital and Medical School, University of Tampere, Tampere, Finland.</nlm:affiliation>
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<name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G" last="Nordestgaard">B Rge G. Nordestgaard</name>
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<nlm:affiliation>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
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<name sortKey="Key, Timothy J" sort="Key, Timothy J" uniqKey="Key T" first="Timothy J" last="Key">Timothy J. Key</name>
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<name sortKey="Donovan, Jenny L" sort="Donovan, Jenny L" uniqKey="Donovan J" first="Jenny L" last="Donovan">Jenny L. Donovan</name>
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<nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</nlm:affiliation>
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<nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom. University College London, Department of Applied Health Research, 1-19 Torrington Place, London, United Kingdom.</nlm:affiliation>
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<name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
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<nlm:affiliation>Clinical Gerontology Unit, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation>
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<name sortKey="Stanford, Janet L" sort="Stanford, Janet L" uniqKey="Stanford J" first="Janet L" last="Stanford">Janet L. Stanford</name>
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<nlm:affiliation>Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington.</nlm:affiliation>
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<name sortKey="Thibodeau, Stephen N" sort="Thibodeau, Stephen N" uniqKey="Thibodeau S" first="Stephen N" last="Thibodeau">Stephen N. Thibodeau</name>
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<nlm:affiliation>Mayo Clinic, Rochester, Minnesota.</nlm:affiliation>
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<name sortKey="Mcdonnell, Shannon K" sort="Mcdonnell, Shannon K" uniqKey="Mcdonnell S" first="Shannon K" last="Mcdonnell">Shannon K. Mcdonnell</name>
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<nlm:affiliation>Mayo Clinic, Rochester, Minnesota.</nlm:affiliation>
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<name sortKey="Schaid, Daniel J" sort="Schaid, Daniel J" uniqKey="Schaid D" first="Daniel J" last="Schaid">Daniel J. Schaid</name>
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<nlm:affiliation>Mayo Clinic, Rochester, Minnesota.</nlm:affiliation>
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<name sortKey="Maier, Christiane" sort="Maier, Christiane" uniqKey="Maier C" first="Christiane" last="Maier">Christiane Maier</name>
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<nlm:affiliation>Department of Urology, University Hospital Ulm, Ulm, Germany.</nlm:affiliation>
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<name sortKey="Vogel, Walther" sort="Vogel, Walther" uniqKey="Vogel W" first="Walther" last="Vogel">Walther Vogel</name>
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<nlm:affiliation>Institute of Human Genetics, University Hospital Ulm, Ulm, Germany.</nlm:affiliation>
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<author>
<name sortKey="Luedeke, Manuel" sort="Luedeke, Manuel" uniqKey="Luedeke M" first="Manuel" last="Luedeke">Manuel Luedeke</name>
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<nlm:affiliation>Department of Urology, University Hospital Ulm, Ulm, Germany.</nlm:affiliation>
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<author>
<name sortKey="Herkommer, Kathleen" sort="Herkommer, Kathleen" uniqKey="Herkommer K" first="Kathleen" last="Herkommer">Kathleen Herkommer</name>
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<nlm:affiliation>Department of Urology, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kibel, Adam S" sort="Kibel, Adam S" uniqKey="Kibel A" first="Adam S" last="Kibel">Adam S. Kibel</name>
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<nlm:affiliation>Division of Urologic Surgery, Brigham and Womens Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts.</nlm:affiliation>
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</author>
<author>
<name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name>
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<nlm:affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation>
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<author>
<name sortKey="Lubi Ski, Jan" sort="Lubi Ski, Jan" uniqKey="Lubi Ski J" first="Jan" last="Lubi Ski">Jan Lubi Ski</name>
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<nlm:affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Klu Niak, Wojciech" sort="Klu Niak, Wojciech" uniqKey="Klu Niak W" first="Wojciech" last="Klu Niak">Wojciech Klu Niak</name>
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<nlm:affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cannon Albright, Lisa" sort="Cannon Albright, Lisa" uniqKey="Cannon Albright L" first="Lisa" last="Cannon-Albright">Lisa Cannon-Albright</name>
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<nlm:affiliation>Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah. George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name>
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<nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Herrmann, Volker" sort="Herrmann, Volker" uniqKey="Herrmann V" first="Volker" last="Herrmann">Volker Herrmann</name>
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<nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Holleczek, Bernd" sort="Holleczek, Bernd" uniqKey="Holleczek B" first="Bernd" last="Holleczek">Bernd Holleczek</name>
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<nlm:affiliation>Saarland Cancer Registry, Saarbrücken, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Park, Jong Y" sort="Park, Jong Y" uniqKey="Park J" first="Jong Y" last="Park">Jong Y. Park</name>
<affiliation>
<nlm:affiliation>Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sellers, Thomas A" sort="Sellers, Thomas A" uniqKey="Sellers T" first="Thomas A" last="Sellers">Thomas A. Sellers</name>
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<nlm:affiliation>Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lim, Hui Yi" sort="Lim, Hui Yi" uniqKey="Lim H" first="Hui-Yi" last="Lim">Hui-Yi Lim</name>
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<nlm:affiliation>Biostatistics Program, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Slavov, Chavdar" sort="Slavov, Chavdar" uniqKey="Slavov C" first="Chavdar" last="Slavov">Chavdar Slavov</name>
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<nlm:affiliation>Department of Urology and Alexandrovska University Hospital, Medical University, Sofia, Bulgaria.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kaneva, Radka P" sort="Kaneva, Radka P" uniqKey="Kaneva R" first="Radka P" last="Kaneva">Radka P. Kaneva</name>
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<nlm:affiliation>Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University, Sofia, Bulgaria.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mitev, Vanio I" sort="Mitev, Vanio I" uniqKey="Mitev V" first="Vanio I" last="Mitev">Vanio I. Mitev</name>
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<nlm:affiliation>Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University, Sofia, Bulgaria.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Spurdle, Amanda" sort="Spurdle, Amanda" uniqKey="Spurdle A" first="Amanda" last="Spurdle">Amanda Spurdle</name>
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<nlm:affiliation>Molecular Cancer Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Teixeira, Manuel R" sort="Teixeira, Manuel R" uniqKey="Teixeira M" first="Manuel R" last="Teixeira">Manuel R. Teixeira</name>
<affiliation>
<nlm:affiliation>Department of Genetics, Portuguese Oncology Institute, Porto, Portugal. Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Paulo, Paula" sort="Paulo, Paula" uniqKey="Paulo P" first="Paula" last="Paulo">Paula Paulo</name>
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<nlm:affiliation>Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Maia, Sofia" sort="Maia, Sofia" uniqKey="Maia S" first="Sofia" last="Maia">Sofia Maia</name>
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<nlm:affiliation>Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pandha, Hardev" sort="Pandha, Hardev" uniqKey="Pandha H" first="Hardev" last="Pandha">Hardev Pandha</name>
<affiliation>
<nlm:affiliation>The University of Surrey, Guildford, Surrey, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Michael, Agnieszka" sort="Michael, Agnieszka" uniqKey="Michael A" first="Agnieszka" last="Michael">Agnieszka Michael</name>
<affiliation>
<nlm:affiliation>The University of Surrey, Guildford, Surrey, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kierzek, Andrzej" sort="Kierzek, Andrzej" uniqKey="Kierzek A" first="Andrzej" last="Kierzek">Andrzej Kierzek</name>
<affiliation>
<nlm:affiliation>The University of Surrey, Guildford, Surrey, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Batra, Jyotsna" sort="Batra, Jyotsna" uniqKey="Batra J" first="Jyotsna" last="Batra">Jyotsna Batra</name>
<affiliation>
<nlm:affiliation>Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Clements, Judith A" sort="Clements, Judith A" uniqKey="Clements J" first="Judith A" last="Clements">Judith A. Clements</name>
<affiliation>
<nlm:affiliation>Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Andriole, Gerald L" sort="Andriole, Gerald L" uniqKey="Andriole G" first="Gerald L" last="Andriole">Gerald L. Andriole</name>
<affiliation>
<nlm:affiliation>Washington University School of Medicine, St. Louis, Missouri.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I" last="Berndt">Sonja I. Berndt</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chanock, Stephen" sort="Chanock, Stephen" uniqKey="Chanock S" first="Stephen" last="Chanock">Stephen Chanock</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland. Core Genotyping Facility, Frederick National Laboratory for Cancer Research, Gaithersburg, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gapstur, Susan M" sort="Gapstur, Susan M" uniqKey="Gapstur S" first="Susan M" last="Gapstur">Susan M. Gapstur</name>
<affiliation>
<nlm:affiliation>Epidemiology Research Program, American Cancer Society, Atlanta, Georgia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L" last="Giovannucci">Edward L. Giovannucci</name>
<affiliation>
<nlm:affiliation>Departments of Epidemiology and Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name>
<affiliation>
<nlm:affiliation>Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name>
<affiliation>
<nlm:affiliation>Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name>
<affiliation>
<nlm:affiliation>Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii.</nlm:affiliation>
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</author>
<author>
<name sortKey="Ma, Jing" sort="Ma, Jing" uniqKey="Ma J" first="Jing" last="Ma">Jing Ma</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Brigham and Women's Hospital Channing Laboratory, Boston, Massachusetts. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
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<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.</nlm:affiliation>
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<author>
<name sortKey="Penney, Kathryn L" sort="Penney, Kathryn L" uniqKey="Penney K" first="Kathryn L" last="Penney">Kathryn L. Penney</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Brigham and Women's Hospital Channing Laboratory, Boston, Massachusetts. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
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<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.</nlm:affiliation>
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<name sortKey="Stevens, Victoria L" sort="Stevens, Victoria L" uniqKey="Stevens V" first="Victoria L" last="Stevens">Victoria L. Stevens</name>
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<nlm:affiliation>Epidemiology Research Program, American Cancer Society, Atlanta, Georgia.</nlm:affiliation>
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<name sortKey="Weinstein, Stephanie J" sort="Weinstein, Stephanie J" uniqKey="Weinstein S" first="Stephanie J" last="Weinstein">Stephanie J. Weinstein</name>
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<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.</nlm:affiliation>
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<name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name>
<affiliation>
<nlm:affiliation>Hellenic Health Foundation, Athens, Greece. Department of Hygiene, Epidemiology, and Medical Statistics, University of Athens Medical School, Athens, Greece. Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece.</nlm:affiliation>
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<name sortKey="Bueno De Mesquita, Bas H" sort="Bueno De Mesquita, Bas H" uniqKey="Bueno De Mesquita B" first="Bas H" last="Bueno-De-Mesquita">Bas H. Bueno-De-Mesquita</name>
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<nlm:affiliation>Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, the Netherlands. Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, United Kingdom. Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation>
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<nlm:affiliation>Danish Cancer Society Research Center, Copenhagen, Denmark.</nlm:affiliation>
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<author>
<name sortKey="Cox, David G" sort="Cox, David G" uniqKey="Cox D" first="David G" last="Cox">David G. Cox</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom. Cancer Research Center of Lyon, INSERM UMR1052, Center Léon Bérard, Lyon, France.</nlm:affiliation>
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<nlm:affiliation>Inherited Cancer Research Group, Department for Medical Genetics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.</nlm:affiliation>
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<nlm:affiliation>Department of Medical Biochemistry and Genetics, Institute of Biomedicine Kiinamyllynkatu 10, University of Turku, Turku, Finland. BioMediTech, University of Tampere and FimLab Laboratories, Tampere, Finland.</nlm:affiliation>
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<nlm:affiliation>Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.</nlm:affiliation>
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<name sortKey="Wiklund, Fredrik" sort="Wiklund, Fredrik" uniqKey="Wiklund F" first="Fredrik" last="Wiklund">Fredrik Wiklund</name>
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<nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</nlm:affiliation>
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</titleStmt>
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<date when="2015">2015</date>
<idno type="RBID">pubmed:26307654</idno>
<idno type="pmid">26307654</idno>
<idno type="doi">10.1158/1055-9965.EPI-15-0543</idno>
<idno type="wicri:Area/PubMed/Corpus">002792</idno>
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<nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden. Academic Primary Healthcare Center, Stockholm County Council, Karolinska Institute, Stockholm, Sweden. robert.szulkin@ki.se.</nlm:affiliation>
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<nlm:affiliation>Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Grattan Street, Parkville, Victoria, Australia.</nlm:affiliation>
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<nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.</nlm:affiliation>
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<nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California.</nlm:affiliation>
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<name sortKey="Schumacher, Fredrick R" sort="Schumacher, Fredrick R" uniqKey="Schumacher F" first="Fredrick R" last="Schumacher">Fredrick R. Schumacher</name>
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<nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California.</nlm:affiliation>
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<name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name>
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<nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California.</nlm:affiliation>
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<name sortKey="Sipeky, Csilla" sort="Sipeky, Csilla" uniqKey="Sipeky C" first="Csilla" last="Sipeky">Csilla Sipeky</name>
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<nlm:affiliation>Department of Medical Biochemistry and Genetics, Institute of Biomedicine Kiinamyllynkatu 10, University of Turku, Turku, Finland.</nlm:affiliation>
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<name sortKey="Tammela, Teuvo L J" sort="Tammela, Teuvo L J" uniqKey="Tammela T" first="Teuvo L J" last="Tammela">Teuvo L J. Tammela</name>
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<nlm:affiliation>Department of Urology, Tampere University Hospital and Medical School, University of Tampere, Tampere, Finland.</nlm:affiliation>
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<name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G" last="Nordestgaard">B Rge G. Nordestgaard</name>
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<nlm:affiliation>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation>
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<name sortKey="Key, Timothy J" sort="Key, Timothy J" uniqKey="Key T" first="Timothy J" last="Key">Timothy J. Key</name>
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<nlm:affiliation>Cancer Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.</nlm:affiliation>
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<nlm:affiliation>Cancer Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.</nlm:affiliation>
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<name sortKey="Neal, David E" sort="Neal, David E" uniqKey="Neal D" first="David E" last="Neal">David E. Neal</name>
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<nlm:affiliation>Department of Oncology, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom. Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom.</nlm:affiliation>
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<name sortKey="Donovan, Jenny L" sort="Donovan, Jenny L" uniqKey="Donovan J" first="Jenny L" last="Donovan">Jenny L. Donovan</name>
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<nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</nlm:affiliation>
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<name sortKey="Hamdy, Freddie C" sort="Hamdy, Freddie C" uniqKey="Hamdy F" first="Freddie C" last="Hamdy">Freddie C. Hamdy</name>
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<nlm:affiliation>Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; Faculty of Medical Science, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.</nlm:affiliation>
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<nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.</nlm:affiliation>
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<name sortKey="Pashayan, Nora" sort="Pashayan, Nora" uniqKey="Pashayan N" first="Nora" last="Pashayan">Nora Pashayan</name>
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<nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom. University College London, Department of Applied Health Research, 1-19 Torrington Place, London, United Kingdom.</nlm:affiliation>
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<nlm:affiliation>Clinical Gerontology Unit, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation>
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<name sortKey="Stanford, Janet L" sort="Stanford, Janet L" uniqKey="Stanford J" first="Janet L" last="Stanford">Janet L. Stanford</name>
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<nlm:affiliation>Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington.</nlm:affiliation>
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<name sortKey="Thibodeau, Stephen N" sort="Thibodeau, Stephen N" uniqKey="Thibodeau S" first="Stephen N" last="Thibodeau">Stephen N. Thibodeau</name>
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<nlm:affiliation>Mayo Clinic, Rochester, Minnesota.</nlm:affiliation>
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<name sortKey="Mcdonnell, Shannon K" sort="Mcdonnell, Shannon K" uniqKey="Mcdonnell S" first="Shannon K" last="Mcdonnell">Shannon K. Mcdonnell</name>
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<nlm:affiliation>Mayo Clinic, Rochester, Minnesota.</nlm:affiliation>
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<name sortKey="Schaid, Daniel J" sort="Schaid, Daniel J" uniqKey="Schaid D" first="Daniel J" last="Schaid">Daniel J. Schaid</name>
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<nlm:affiliation>Mayo Clinic, Rochester, Minnesota.</nlm:affiliation>
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<name sortKey="Maier, Christiane" sort="Maier, Christiane" uniqKey="Maier C" first="Christiane" last="Maier">Christiane Maier</name>
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<nlm:affiliation>Department of Urology, University Hospital Ulm, Ulm, Germany.</nlm:affiliation>
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<name sortKey="Vogel, Walther" sort="Vogel, Walther" uniqKey="Vogel W" first="Walther" last="Vogel">Walther Vogel</name>
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<nlm:affiliation>Institute of Human Genetics, University Hospital Ulm, Ulm, Germany.</nlm:affiliation>
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<name sortKey="Luedeke, Manuel" sort="Luedeke, Manuel" uniqKey="Luedeke M" first="Manuel" last="Luedeke">Manuel Luedeke</name>
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<nlm:affiliation>Department of Urology, University Hospital Ulm, Ulm, Germany.</nlm:affiliation>
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<author>
<name sortKey="Herkommer, Kathleen" sort="Herkommer, Kathleen" uniqKey="Herkommer K" first="Kathleen" last="Herkommer">Kathleen Herkommer</name>
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<nlm:affiliation>Department of Urology, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany.</nlm:affiliation>
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<author>
<name sortKey="Kibel, Adam S" sort="Kibel, Adam S" uniqKey="Kibel A" first="Adam S" last="Kibel">Adam S. Kibel</name>
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<nlm:affiliation>Division of Urologic Surgery, Brigham and Womens Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts.</nlm:affiliation>
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<name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name>
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<nlm:affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation>
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<name sortKey="Lubi Ski, Jan" sort="Lubi Ski, Jan" uniqKey="Lubi Ski J" first="Jan" last="Lubi Ski">Jan Lubi Ski</name>
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<nlm:affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation>
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<name sortKey="Klu Niak, Wojciech" sort="Klu Niak, Wojciech" uniqKey="Klu Niak W" first="Wojciech" last="Klu Niak">Wojciech Klu Niak</name>
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<nlm:affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation>
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<name sortKey="Cannon Albright, Lisa" sort="Cannon Albright, Lisa" uniqKey="Cannon Albright L" first="Lisa" last="Cannon-Albright">Lisa Cannon-Albright</name>
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<nlm:affiliation>Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah. George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.</nlm:affiliation>
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<name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name>
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<nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation>
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<name sortKey="Herrmann, Volker" sort="Herrmann, Volker" uniqKey="Herrmann V" first="Volker" last="Herrmann">Volker Herrmann</name>
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<nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation>
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</author>
<author>
<name sortKey="Holleczek, Bernd" sort="Holleczek, Bernd" uniqKey="Holleczek B" first="Bernd" last="Holleczek">Bernd Holleczek</name>
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<nlm:affiliation>Saarland Cancer Registry, Saarbrücken, Germany.</nlm:affiliation>
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<author>
<name sortKey="Park, Jong Y" sort="Park, Jong Y" uniqKey="Park J" first="Jong Y" last="Park">Jong Y. Park</name>
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<nlm:affiliation>Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation>
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</author>
<author>
<name sortKey="Sellers, Thomas A" sort="Sellers, Thomas A" uniqKey="Sellers T" first="Thomas A" last="Sellers">Thomas A. Sellers</name>
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<nlm:affiliation>Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation>
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<name sortKey="Lim, Hui Yi" sort="Lim, Hui Yi" uniqKey="Lim H" first="Hui-Yi" last="Lim">Hui-Yi Lim</name>
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<nlm:affiliation>Biostatistics Program, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation>
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<name sortKey="Slavov, Chavdar" sort="Slavov, Chavdar" uniqKey="Slavov C" first="Chavdar" last="Slavov">Chavdar Slavov</name>
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<nlm:affiliation>Department of Urology and Alexandrovska University Hospital, Medical University, Sofia, Bulgaria.</nlm:affiliation>
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<name sortKey="Kaneva, Radka P" sort="Kaneva, Radka P" uniqKey="Kaneva R" first="Radka P" last="Kaneva">Radka P. Kaneva</name>
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<nlm:affiliation>Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University, Sofia, Bulgaria.</nlm:affiliation>
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<name sortKey="Mitev, Vanio I" sort="Mitev, Vanio I" uniqKey="Mitev V" first="Vanio I" last="Mitev">Vanio I. Mitev</name>
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<nlm:affiliation>Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University, Sofia, Bulgaria.</nlm:affiliation>
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<name sortKey="Spurdle, Amanda" sort="Spurdle, Amanda" uniqKey="Spurdle A" first="Amanda" last="Spurdle">Amanda Spurdle</name>
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<nlm:affiliation>Molecular Cancer Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia.</nlm:affiliation>
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<name sortKey="Teixeira, Manuel R" sort="Teixeira, Manuel R" uniqKey="Teixeira M" first="Manuel R" last="Teixeira">Manuel R. Teixeira</name>
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<nlm:affiliation>Department of Genetics, Portuguese Oncology Institute, Porto, Portugal. Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal.</nlm:affiliation>
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<name sortKey="Paulo, Paula" sort="Paulo, Paula" uniqKey="Paulo P" first="Paula" last="Paulo">Paula Paulo</name>
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<nlm:affiliation>Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Maia, Sofia" sort="Maia, Sofia" uniqKey="Maia S" first="Sofia" last="Maia">Sofia Maia</name>
<affiliation>
<nlm:affiliation>Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pandha, Hardev" sort="Pandha, Hardev" uniqKey="Pandha H" first="Hardev" last="Pandha">Hardev Pandha</name>
<affiliation>
<nlm:affiliation>The University of Surrey, Guildford, Surrey, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Michael, Agnieszka" sort="Michael, Agnieszka" uniqKey="Michael A" first="Agnieszka" last="Michael">Agnieszka Michael</name>
<affiliation>
<nlm:affiliation>The University of Surrey, Guildford, Surrey, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kierzek, Andrzej" sort="Kierzek, Andrzej" uniqKey="Kierzek A" first="Andrzej" last="Kierzek">Andrzej Kierzek</name>
<affiliation>
<nlm:affiliation>The University of Surrey, Guildford, Surrey, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Batra, Jyotsna" sort="Batra, Jyotsna" uniqKey="Batra J" first="Jyotsna" last="Batra">Jyotsna Batra</name>
<affiliation>
<nlm:affiliation>Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Clements, Judith A" sort="Clements, Judith A" uniqKey="Clements J" first="Judith A" last="Clements">Judith A. Clements</name>
<affiliation>
<nlm:affiliation>Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Andriole, Gerald L" sort="Andriole, Gerald L" uniqKey="Andriole G" first="Gerald L" last="Andriole">Gerald L. Andriole</name>
<affiliation>
<nlm:affiliation>Washington University School of Medicine, St. Louis, Missouri.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I" last="Berndt">Sonja I. Berndt</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chanock, Stephen" sort="Chanock, Stephen" uniqKey="Chanock S" first="Stephen" last="Chanock">Stephen Chanock</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland. Core Genotyping Facility, Frederick National Laboratory for Cancer Research, Gaithersburg, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gapstur, Susan M" sort="Gapstur, Susan M" uniqKey="Gapstur S" first="Susan M" last="Gapstur">Susan M. Gapstur</name>
<affiliation>
<nlm:affiliation>Epidemiology Research Program, American Cancer Society, Atlanta, Georgia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L" last="Giovannucci">Edward L. Giovannucci</name>
<affiliation>
<nlm:affiliation>Departments of Epidemiology and Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name>
<affiliation>
<nlm:affiliation>Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name>
<affiliation>
<nlm:affiliation>Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name>
<affiliation>
<nlm:affiliation>Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ma, Jing" sort="Ma, Jing" uniqKey="Ma J" first="Jing" last="Ma">Jing Ma</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Brigham and Women's Hospital Channing Laboratory, Boston, Massachusetts. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mondul, Alison M" sort="Mondul, Alison M" uniqKey="Mondul A" first="Alison M" last="Mondul">Alison M. Mondul</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Penney, Kathryn L" sort="Penney, Kathryn L" uniqKey="Penney K" first="Kathryn L" last="Penney">Kathryn L. Penney</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Brigham and Women's Hospital Channing Laboratory, Boston, Massachusetts. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Stampfer, Meir J" sort="Stampfer, Meir J" uniqKey="Stampfer M" first="Meir J" last="Stampfer">Meir J. Stampfer</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Stevens, Victoria L" sort="Stevens, Victoria L" uniqKey="Stevens V" first="Victoria L" last="Stevens">Victoria L. Stevens</name>
<affiliation>
<nlm:affiliation>Epidemiology Research Program, American Cancer Society, Atlanta, Georgia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Weinstein, Stephanie J" sort="Weinstein, Stephanie J" uniqKey="Weinstein S" first="Stephanie J" last="Weinstein">Stephanie J. Weinstein</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name>
<affiliation>
<nlm:affiliation>Hellenic Health Foundation, Athens, Greece. Department of Hygiene, Epidemiology, and Medical Statistics, University of Athens Medical School, Athens, Greece. Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bueno De Mesquita, Bas H" sort="Bueno De Mesquita, Bas H" uniqKey="Bueno De Mesquita B" first="Bas H" last="Bueno-De-Mesquita">Bas H. Bueno-De-Mesquita</name>
<affiliation>
<nlm:affiliation>Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, the Netherlands. Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, United Kingdom. Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name>
<affiliation>
<nlm:affiliation>Danish Cancer Society Research Center, Copenhagen, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cox, David G" sort="Cox, David G" uniqKey="Cox D" first="David G" last="Cox">David G. Cox</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom. Cancer Research Center of Lyon, INSERM UMR1052, Center Léon Bérard, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Maehle, Lovise" sort="Maehle, Lovise" uniqKey="Maehle L" first="Lovise" last="Maehle">Lovise Maehle</name>
<affiliation>
<nlm:affiliation>Inherited Cancer Research Group, Department for Medical Genetics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Schleutker, Johanna" sort="Schleutker, Johanna" uniqKey="Schleutker J" first="Johanna" last="Schleutker">Johanna Schleutker</name>
<affiliation>
<nlm:affiliation>Department of Medical Biochemistry and Genetics, Institute of Biomedicine Kiinamyllynkatu 10, University of Turku, Turku, Finland. BioMediTech, University of Tampere and FimLab Laboratories, Tampere, Finland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lindstrom, Sara" sort="Lindstrom, Sara" uniqKey="Lindstrom S" first="Sara" last="Lindström">Sara Lindström</name>
<affiliation>
<nlm:affiliation>Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wiklund, Fredrik" sort="Wiklund, Fredrik" uniqKey="Wiklund F" first="Fredrik" last="Wiklund">Fredrik Wiklund</name>
<affiliation>
<nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology</title>
<idno type="eISSN">1538-7755</idno>
<imprint>
<date when="2015" type="published">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Genome-Wide Association Study</term>
<term>Humans</term>
<term>Male</term>
<term>Polymorphism, Single Nucleotide (genetics)</term>
<term>Prostatic Neoplasms (genetics)</term>
<term>Prostatic Neoplasms (mortality)</term>
<term>Survival Analysis</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en">
<term>Polymorphism, Single Nucleotide</term>
<term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en">
<term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Genome-Wide Association Study</term>
<term>Humans</term>
<term>Male</term>
<term>Survival Analysis</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">26307654</PMID>
<DateCreated>
<Year>2015</Year>
<Month>11</Month>
<Day>04</Day>
</DateCreated>
<DateCompleted>
<Year>2016</Year>
<Month>08</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised>
<Year>2017</Year>
<Month>11</Month>
<Day>08</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1538-7755</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>24</Volume>
<Issue>11</Issue>
<PubDate>
<Year>2015</Year>
<Month>Nov</Month>
</PubDate>
</JournalIssue>
<Title>Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology</Title>
<ISOAbbreviation>Cancer Epidemiol. Biomarkers Prev.</ISOAbbreviation>
</Journal>
<ArticleTitle>Genome-wide association study of prostate cancer-specific survival.</ArticleTitle>
<Pagination>
<MedlinePgn>1796-800</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1158/1055-9965.EPI-15-0543</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We performed a genome-wide survival analysis of cause-specific death in 24,023 prostate cancer patients (3,513 disease-specific deaths) from the PRACTICAL and BPC3 consortia. Top findings were assessed for replication in a Norwegian cohort (CONOR).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">We observed no significant association between genetic variants and prostate cancer survival.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Common genetic variants with large impact on prostate cancer survival were not observed in this study.</AbstractText>
<AbstractText Label="IMPACT" NlmCategory="CONCLUSIONS">Future studies should be designed for identification of rare variants with large effect sizes or common variants with small effect sizes.</AbstractText>
<CopyrightInformation>©2015 American Association for Cancer Research.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Szulkin</LastName>
<ForeName>Robert</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden. Academic Primary Healthcare Center, Stockholm County Council, Karolinska Institute, Stockholm, Sweden. robert.szulkin@ki.se.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Karlsson</LastName>
<ForeName>Robert</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Whitington</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Aly</LastName>
<ForeName>Markus</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Gronberg</LastName>
<ForeName>Henrik</ForeName>
<Initials>H</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Eeles</LastName>
<ForeName>Rosalind A</ForeName>
<Initials>RA</Initials>
<AffiliationInfo>
<Affiliation>The Institute of Cancer Research, London, United Kingdom. Royal Marsden National Health Service (NHS) Foundation Trust, London and Sutton, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Easton</LastName>
<ForeName>Douglas F</ForeName>
<Initials>DF</Initials>
<AffiliationInfo>
<Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Kote-Jarai</LastName>
<ForeName>Zsofia</ForeName>
<Initials>Z</Initials>
<AffiliationInfo>
<Affiliation>The Institute of Cancer Research, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Al Olama</LastName>
<ForeName>Ali Amin</ForeName>
<Initials>AA</Initials>
<AffiliationInfo>
<Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Benlloch</LastName>
<ForeName>Sara</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Muir</LastName>
<ForeName>Kenneth</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Institute of Population Health, University of Manchester, Manchester, United Kingdom. Warwick Medical School, University of Warwick, Coventry, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Giles</LastName>
<ForeName>Graham G</ForeName>
<Initials>GG</Initials>
<AffiliationInfo>
<Affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Southey</LastName>
<ForeName>Melissa C</ForeName>
<Initials>MC</Initials>
<AffiliationInfo>
<Affiliation>Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Grattan Street, Parkville, Victoria, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>FitzGerald</LastName>
<ForeName>Liesel M</ForeName>
<Initials>LM</Initials>
<AffiliationInfo>
<Affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Henderson</LastName>
<ForeName>Brian E</ForeName>
<Initials>BE</Initials>
<AffiliationInfo>
<Affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Schumacher</LastName>
<ForeName>Fredrick R</ForeName>
<Initials>FR</Initials>
<AffiliationInfo>
<Affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Haiman</LastName>
<ForeName>Christopher A</ForeName>
<Initials>CA</Initials>
<AffiliationInfo>
<Affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sipeky</LastName>
<ForeName>Csilla</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Biochemistry and Genetics, Institute of Biomedicine Kiinamyllynkatu 10, University of Turku, Turku, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Tammela</LastName>
<ForeName>Teuvo L J</ForeName>
<Initials>TL</Initials>
<AffiliationInfo>
<Affiliation>Department of Urology, Tampere University Hospital and Medical School, University of Tampere, Tampere, Finland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Nordestgaard</LastName>
<ForeName>Børge G</ForeName>
<Initials>BG</Initials>
<AffiliationInfo>
<Affiliation>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Key</LastName>
<ForeName>Timothy J</ForeName>
<Initials>TJ</Initials>
<AffiliationInfo>
<Affiliation>Cancer Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Travis</LastName>
<ForeName>Ruth C</ForeName>
<Initials>RC</Initials>
<AffiliationInfo>
<Affiliation>Cancer Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Neal</LastName>
<ForeName>David E</ForeName>
<Initials>DE</Initials>
<AffiliationInfo>
<Affiliation>Department of Oncology, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom. Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Donovan</LastName>
<ForeName>Jenny L</ForeName>
<Initials>JL</Initials>
<AffiliationInfo>
<Affiliation>School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Hamdy</LastName>
<ForeName>Freddie C</ForeName>
<Initials>FC</Initials>
<AffiliationInfo>
<Affiliation>Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; Faculty of Medical Science, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Pharoah</LastName>
<ForeName>Paul D P</ForeName>
<Initials>PD</Initials>
<AffiliationInfo>
<Affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Pashayan</LastName>
<ForeName>Nora</ForeName>
<Initials>N</Initials>
<AffiliationInfo>
<Affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom. University College London, Department of Applied Health Research, 1-19 Torrington Place, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Khaw</LastName>
<ForeName>Kay-Tee</ForeName>
<Initials>KT</Initials>
<AffiliationInfo>
<Affiliation>Clinical Gerontology Unit, University of Cambridge, Cambridge, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Stanford</LastName>
<ForeName>Janet L</ForeName>
<Initials>JL</Initials>
<AffiliationInfo>
<Affiliation>Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Thibodeau</LastName>
<ForeName>Stephen N</ForeName>
<Initials>SN</Initials>
<AffiliationInfo>
<Affiliation>Mayo Clinic, Rochester, Minnesota.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>McDonnell</LastName>
<ForeName>Shannon K</ForeName>
<Initials>SK</Initials>
<AffiliationInfo>
<Affiliation>Mayo Clinic, Rochester, Minnesota.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Schaid</LastName>
<ForeName>Daniel J</ForeName>
<Initials>DJ</Initials>
<AffiliationInfo>
<Affiliation>Mayo Clinic, Rochester, Minnesota.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Maier</LastName>
<ForeName>Christiane</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Department of Urology, University Hospital Ulm, Ulm, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Vogel</LastName>
<ForeName>Walther</ForeName>
<Initials>W</Initials>
<AffiliationInfo>
<Affiliation>Institute of Human Genetics, University Hospital Ulm, Ulm, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Luedeke</LastName>
<ForeName>Manuel</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Urology, University Hospital Ulm, Ulm, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Herkommer</LastName>
<ForeName>Kathleen</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Urology, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany.</Affiliation>
</AffiliationInfo>
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