Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Identifieur interne : 002466 ( PubMed/Corpus ); précédent : 002465; suivant : 002467Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Auteurs : Cristian Pattaro ; Alexander Teumer ; Mathias Gorski ; Audrey Y. Chu ; Man Li ; Vladan Mijatovic ; Maija Garnaas ; Adrienne Tin ; Rossella Sorice ; Yong Li ; Daniel Taliun ; Matthias Olden ; Meredith Foster ; Qiong Yang ; Ming-Huei Chen ; Tune H. Pers ; Andrew D. Johnson ; Yi-An Ko ; Christian Fuchsberger ; Bamidele Tayo ; Michael Nalls ; Mary F. Feitosa ; Aaron Isaacs ; Abbas Dehghan ; Pio D'Adamo ; Adebowale Adeyemo ; Aida Karina Dieffenbach ; Alan B. Zonderman ; Ilja M. Nolte ; Peter J. Van Der Most ; Alan F. Wright ; Alan R. Shuldiner ; Alanna C. Morrison ; Albert Hofman ; Albert V. Smith ; Albert W. Dreisbach ; Andre Franke ; Andre G. Uitterlinden ; Andres Metspalu ; Anke Tonjes ; Antonio Lupo ; Antonietta Robino ; Sa Johansson ; Ayse Demirkan ; Barbara Kollerits ; Barry I. Freedman ; Belen Ponte ; Ben A. Oostra ; Bernhard Paulweber ; Bernhard K. Kr Mer ; Braxton D. Mitchell ; Brendan M. Buckley ; Carmen A. Peralta ; Caroline Hayward ; Catherine Helmer ; Charles N. Rotimi ; Christian M. Shaffer ; Christian Müller ; Cinzia Sala ; Cornelia M. Van Duijn ; Aude Saint-Pierre ; Daniel Ackermann ; Daniel Shriner ; Daniela Ruggiero ; Daniela Toniolo ; Yingchang Lu ; Daniele Cusi ; Darina Czamara ; David Ellinghaus ; David S. Siscovick ; Douglas Ruderfer ; Christian Gieger ; Harald Grallert ; Elena Rochtchina ; Elizabeth J. Atkinson ; Elizabeth G. Holliday ; Eric Boerwinkle ; Erika Salvi ; Erwin P. Bottinger ; Federico Murgia ; Fernando Rivadeneira ; Florian Ernst ; Florian Kronenberg ; Frank B. Hu ; Gerjan J. Navis ; Gary C. Curhan ; George B. Ehret ; Georg Homuth ; Stefan Coassin ; Gian-Andri Thun ; Giorgio Pistis ; Giovanni Gambaro ; Giovanni Malerba ; Grant W. Montgomery ; Gudny Eiriksdottir ; Gunnar Jacobs ; Guo Li ; H-Erich Wichmann ; Harry Campbell ; Helena Schmidt ; Henri Wallaschofski ; Henry Völzke ; Hermann Brenner ; Heyo K. Kroemer ; Holly Kramer ; Honghuang Lin ; I Mateo Leach ; Ian Ford ; Idris Guessous ; Igor Rudan ; Inga Prokopenko ; Ingrid Borecki ; Iris M. Heid ; Ivana Kolcic ; Ivana Persico ; J Wouter Jukema ; James F. Wilson ; Janine F. Felix ; Jasmin Divers ; Jean-Charles Lambert ; Jeanette M. Stafford ; Jean-Michel Gaspoz ; Jennifer A. Smith ; Jessica D. Faul ; Jie Jin Wang ; Jingzhong Ding ; Joel N. Hirschhorn ; John Attia ; John B. Whitfield ; John Chalmers ; Jorma Viikari ; Josef Coresh ; Joshua C. Denny ; Juha Karjalainen ; Jyotika K. Fernandes ; Karlhans Endlich ; Katja Butterbach ; Keith L. Keene ; Kurt Lohman ; Laura Portas ; Lenore J. Launer ; Leo-Pekka Lyytik Inen ; Loic Yengo ; Lude Franke ; Luigi Ferrucci ; Lynda M. Rose ; Lyudmyla Kedenko ; Madhumathi Rao ; Maksim Struchalin ; Marcus E. Kleber ; Margherita Cavalieri ; Margot Haun ; Marilyn C. Cornelis ; Marina Ciullo ; Mario Pirastu ; Mariza De Andrade ; Mark A. Mcevoy ; Mark Woodward ; Martin Adam ; Massimiliano Cocca ; Matthias Nauck ; Medea Imboden ; Melanie Waldenberger ; Menno Pruijm ; Marie Metzger ; Michael Stumvoll ; Michele K. Evans ; Michele M. Sale ; Mika K Hönen ; Mladen Boban ; Murielle Bochud ; Myriam Rheinberger ; Niek Verweij ; Nabila Bouatia-Naji ; Nicholas G. Martin ; Nick Hastie ; Nicole Probst-Hensch ; Nicole Soranzo ; Olivier Devuyst ; Olli Raitakari ; Omri Gottesman ; Oscar H. Franco ; Ozren Polasek ; Paolo Gasparini ; Patricia B. Munroe ; Paul M. Ridker ; Paul Mitchell ; Paul Muntner ; Christa Meisinger ; Johannes H. Smit ; Peter Kovacs ; Philipp S. Wild ; Philippe Froguel ; Rainer Rettig ; Reedik M Gi ; Reiner Biffar ; Reinhold Schmidt ; Rita P S. Middelberg ; Robert J. Carroll ; Brenda W. Penninx ; Rodney J. Scott ; Ronit Katz ; Sanaz Sedaghat ; Sarah H. Wild ; Sharon L R. Kardia ; Sheila Ulivi ; Shih-Jen Hwang ; Stefan Enroth ; Stefan Kloiber ; Stella Trompet ; Benedicte Stengel ; Stephen J. Hancock ; Stephen T. Turner ; Sylvia E. Rosas ; Sylvia Stracke ; Tamara B. Harris ; Tanja Zeller ; Tatijana Zemunik ; Terho Lehtim Ki ; Thomas Illig ; Thor Aspelund ; Tiit Nikopensius ; Tonu Esko ; Toshiko Tanaka ; Ulf Gyllensten ; Uwe Völker ; Valur Emilsson ; Veronique Vitart ; Ville Aalto ; Vilmundur Gudnason ; Vincent Chouraki ; Wei-Min Chen ; Wilmar Igl ; Winfried M Rz ; Wolfgang Koenig ; Wolfgang Lieb ; Ruth J F. Loos ; Yongmei Liu ; Harold Snieder ; Peter P. Pramstaller ; Afshin Parsa ; Jeffrey R. O'Connell ; Katalin Susztak ; Pavel Hamet ; Johanne Tremblay ; Ian H. De Boer ; Carsten A. Böger ; Wolfram Goessling ; Daniel I. Chasman ; Anna Köttgen ; W H Linda Kao ; Caroline S. FoxSource :
- Nature communications [ 2041-1723 ] ; 2016.
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Abstract
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. We identify 24 new and confirm 29 previously identified loci. Of these 53 loci, 19 associate with eGFR among individuals with diabetes. Using bioinformatics, we show that identified genes at eGFR loci are enriched for expression in kidney tissues and in pathways relevant for kidney development and transmembrane transporter activity, kidney structure, and regulation of glucose metabolism. Chromatin state mapping and DNase I hypersensitivity analyses across adult tissues demonstrate preferential mapping of associated variants to regulatory regions in kidney but not extra-renal tissues. These findings suggest that genetic determinants of eGFR are mediated largely through direct effects within the kidney and highlight important cell types and biological pathways.
DOI: 10.1038/ncomms10023
PubMed: 26831199
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.</title><author><name sortKey="Pattaro, Cristian" sort="Pattaro, Cristian" uniqKey="Pattaro C" first="Cristian" last="Pattaro">Cristian Pattaro</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name><affiliation><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Chu, Audrey Y" sort="Chu, Audrey Y" uniqKey="Chu A" first="Audrey Y" last="Chu">Audrey Y. Chu</name><affiliation><nlm:affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mijatovic, Vladan" sort="Mijatovic, Vladan" uniqKey="Mijatovic V" first="Vladan" last="Mijatovic">Vladan Mijatovic</name><affiliation><nlm:affiliation>Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, Verona 37134, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Garnaas, Maija" sort="Garnaas, Maija" uniqKey="Garnaas M" first="Maija" last="Garnaas">Maija Garnaas</name><affiliation><nlm:affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, New Research Building77 Avenue Louis Pasteur, Room 458, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Tin, Adrienne" sort="Tin, Adrienne" uniqKey="Tin A" first="Adrienne" last="Tin">Adrienne Tin</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sorice, Rossella" sort="Sorice, Rossella" uniqKey="Sorice R" first="Rossella" last="Sorice">Rossella Sorice</name><affiliation><nlm:affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name><affiliation><nlm:affiliation>Department of Internal Medicine IV, University Hospital Freiburg, Berliner Allee 29, Freiburg 79110, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Taliun, Daniel" sort="Taliun, Daniel" uniqKey="Taliun D" first="Daniel" last="Taliun">Daniel Taliun</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Olden, Matthias" sort="Olden, Matthias" uniqKey="Olden M" first="Matthias" last="Olden">Matthias Olden</name><affiliation><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Foster, Meredith" sort="Foster, Meredith" uniqKey="Foster M" first="Meredith" last="Foster">Meredith Foster</name><affiliation><nlm:affiliation>Division of Nephrology/Tufts Evidence Practice Center, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Yang, Qiong" sort="Yang, Qiong" uniqKey="Yang Q" first="Qiong" last="Yang">Qiong Yang</name><affiliation><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, Massachusetts 02118, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, Ming Huei" sort="Chen, Ming Huei" uniqKey="Chen M" first="Ming-Huei" last="Chen">Ming-Huei Chen</name><affiliation><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, Massachusetts 02118, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H" last="Pers">Tune H. Pers</name><affiliation><nlm:affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D" last="Johnson">Andrew D. Johnson</name><affiliation><nlm:affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ko, Yi An" sort="Ko, Yi An" uniqKey="Ko Y" first="Yi-An" last="Ko">Yi-An Ko</name><affiliation><nlm:affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Fuchsberger, Christian" sort="Fuchsberger, Christian" uniqKey="Fuchsberger C" first="Christian" last="Fuchsberger">Christian Fuchsberger</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Tayo, Bamidele" sort="Tayo, Bamidele" uniqKey="Tayo B" first="Bamidele" last="Tayo">Bamidele Tayo</name><affiliation><nlm:affiliation>Department of Public Health Sciences, Loyola Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Nalls, Michael" sort="Nalls, Michael" uniqKey="Nalls M" first="Michael" last="Nalls">Michael Nalls</name><affiliation><nlm:affiliation>Laboratory of Neurogenetics, Building 35-Porter Building, 1A1015, National Institute on Aging/NIH, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F" last="Feitosa">Mary F. Feitosa</name><affiliation><nlm:affiliation>Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Box 8506, St Louis, Missouri 63108, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Isaacs, Aaron" sort="Isaacs, Aaron" uniqKey="Isaacs A" first="Aaron" last="Isaacs">Aaron Isaacs</name><affiliation><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="D Adamo, Pio" sort="D Adamo, Pio" uniqKey="D Adamo P" first="Pio" last="D'Adamo">Pio D'Adamo</name><affiliation><nlm:affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Adeyemo, Adebowale" sort="Adeyemo, Adebowale" uniqKey="Adeyemo A" first="Adebowale" last="Adeyemo">Adebowale Adeyemo</name><affiliation><nlm:affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Dieffenbach, Aida Karina" sort="Dieffenbach, Aida Karina" uniqKey="Dieffenbach A" first="Aida Karina" last="Dieffenbach">Aida Karina Dieffenbach</name><affiliation><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Zonderman, Alan B" sort="Zonderman, Alan B" uniqKey="Zonderman A" first="Alan B" last="Zonderman">Alan B. Zonderman</name><affiliation><nlm:affiliation>Laboratory of Personality and Cognition, National Institute on Aging, National Institutes of Health, NIH Biomedical Center, 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><affiliation><nlm:affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Most, Peter J" sort="Van Der Most, Peter J" uniqKey="Van Der Most P" first="Peter J" last="Van Der Most">Peter J. Van Der Most</name><affiliation><nlm:affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><affiliation><nlm:affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name><affiliation><nlm:affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, 1200 Pressler St Suite 453E, Houston, Texas 77030, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Dreisbach, Albert W" sort="Dreisbach, Albert W" uniqKey="Dreisbach A" first="Albert W" last="Dreisbach">Albert W. Dreisbach</name><affiliation><nlm:affiliation>Division of Nephrology, University of Mississippi, 2500 North State Street, Jackson, Mississippi 39216, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name><affiliation><nlm:affiliation>Institute of Clinical Molecular Biology, Christian-Albrechts University of Kiel, Schittenhelmstraße 12, Kiel 24105, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name><affiliation><nlm:affiliation>Department of Internal Medicine, Erasmus University Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation><nlm:affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</nlm:affiliation></affiliation></author><author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tonjes">Anke Tonjes</name><affiliation><nlm:affiliation>Department of Medicine, University of Leipzig, Liebigstraße 18, Leipzig 04103, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Lupo, Antonio" sort="Lupo, Antonio" uniqKey="Lupo A" first="Antonio" last="Lupo">Antonio Lupo</name><affiliation><nlm:affiliation>Division of Nephrology, Department of Medicine, University of Verona, Piazzale Aristide Stefani 1, Verona 37126, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Robino, Antonietta" sort="Robino, Antonietta" uniqKey="Robino A" first="Antonietta" last="Robino">Antonietta Robino</name><affiliation><nlm:affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Johansson, Sa" sort="Johansson, Sa" uniqKey="Johansson " first=" Sa" last="Johansson"> Sa Johansson</name><affiliation><nlm:affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Demirkan, Ayse" sort="Demirkan, Ayse" uniqKey="Demirkan A" first="Ayse" last="Demirkan">Ayse Demirkan</name><affiliation><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Kollerits, Barbara" sort="Kollerits, Barbara" uniqKey="Kollerits B" first="Barbara" last="Kollerits">Barbara Kollerits</name><affiliation><nlm:affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Freedman, Barry I" sort="Freedman, Barry I" uniqKey="Freedman B" first="Barry I" last="Freedman">Barry I. Freedman</name><affiliation><nlm:affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ponte, Belen" sort="Ponte, Belen" uniqKey="Ponte B" first="Belen" last="Ponte">Belen Ponte</name><affiliation><nlm:affiliation>Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospital, 4 rue Gabrielle-Perret-Gentil, Geneve 1211, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Paulweber, Bernhard" sort="Paulweber, Bernhard" uniqKey="Paulweber B" first="Bernhard" last="Paulweber">Bernhard Paulweber</name><affiliation><nlm:affiliation>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Müllner Hauptstraße 48, Salzburg 5020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Kr Mer, Bernhard K" sort="Kr Mer, Bernhard K" uniqKey="Kr Mer B" first="Bernhard K" last="Kr Mer">Bernhard K. Kr Mer</name><affiliation><nlm:affiliation>University Medical Centre Mannheim, 5th Department of Medicine, University of Heidelberg, Theodor Kutzer Ufer 1-3, Mannheim 68167, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Mitchell, Braxton D" sort="Mitchell, Braxton D" uniqKey="Mitchell B" first="Braxton D" last="Mitchell">Braxton D. Mitchell</name><affiliation><nlm:affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Buckley, Brendan M" sort="Buckley, Brendan M" uniqKey="Buckley B" first="Brendan M" last="Buckley">Brendan M. Buckley</name><affiliation><nlm:affiliation>Department of Pharmacology and Therapeutics, University College Cork, Clinical Investigations Building, Western Rd, Cork, Ireland.</nlm:affiliation></affiliation></author><author><name sortKey="Peralta, Carmen A" sort="Peralta, Carmen A" uniqKey="Peralta C" first="Carmen A" last="Peralta">Carmen A. Peralta</name><affiliation><nlm:affiliation>Division of Nephrology, University of California, San Francisco Medical School and San Francisco VA Medical Center, 4150 Clement Street, San Francisco, California 94121, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Helmer, Catherine" sort="Helmer, Catherine" uniqKey="Helmer C" first="Catherine" last="Helmer">Catherine Helmer</name><affiliation><nlm:affiliation>INSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux F-33000, France.</nlm:affiliation></affiliation></author><author><name sortKey="Rotimi, Charles N" sort="Rotimi, Charles N" uniqKey="Rotimi C" first="Charles N" last="Rotimi">Charles N. Rotimi</name><affiliation><nlm:affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Shaffer, Christian M" sort="Shaffer, Christian M" uniqKey="Shaffer C" first="Christian M" last="Shaffer">Christian M. Shaffer</name><affiliation><nlm:affiliation>Vanderbilt University School of Medicine, 2215-B Garland Avenue 1224-MRB4 (Light Hall)Nashville, Tennessee 37232, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Muller, Christian" sort="Muller, Christian" uniqKey="Muller C" first="Christian" last="Müller">Christian Müller</name><affiliation><nlm:affiliation>University Heart Center Hamburg, Clinic for general and interventional cardiology, Martinistraße 52, Hamburg 20246, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Sala, Cinzia" sort="Sala, Cinzia" uniqKey="Sala C" first="Cinzia" last="Sala">Cinzia Sala</name><affiliation><nlm:affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Saint Pierre, Aude" sort="Saint Pierre, Aude" uniqKey="Saint Pierre A" first="Aude" last="Saint-Pierre">Aude Saint-Pierre</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ackermann, Daniel" sort="Ackermann, Daniel" uniqKey="Ackermann D" first="Daniel" last="Ackermann">Daniel Ackermann</name><affiliation><nlm:affiliation>Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospital, 4 rue Gabrielle-Perret-Gentil, Geneve 1211, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Shriner, Daniel" sort="Shriner, Daniel" uniqKey="Shriner D" first="Daniel" last="Shriner">Daniel Shriner</name><affiliation><nlm:affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ruggiero, Daniela" sort="Ruggiero, Daniela" uniqKey="Ruggiero D" first="Daniela" last="Ruggiero">Daniela Ruggiero</name><affiliation><nlm:affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Toniolo, Daniela" sort="Toniolo, Daniela" uniqKey="Toniolo D" first="Daniela" last="Toniolo">Daniela Toniolo</name><affiliation><nlm:affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Lu, Yingchang" sort="Lu, Yingchang" uniqKey="Lu Y" first="Yingchang" last="Lu">Yingchang Lu</name><affiliation><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation><nlm:affiliation>Department of Health Sciences, University of Milano, Via Antonio di Rudinì 8, Milano 20142, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Czamara, Darina" sort="Czamara, Darina" uniqKey="Czamara D" first="Darina" last="Czamara">Darina Czamara</name><affiliation><nlm:affiliation>Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, Munich 80804, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Ellinghaus, David" sort="Ellinghaus, David" uniqKey="Ellinghaus D" first="David" last="Ellinghaus">David Ellinghaus</name><affiliation><nlm:affiliation>Institute of Clinical Molecular Biology, Christian-Albrechts University of Kiel, Schittenhelmstraße 12, Kiel 24105, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Siscovick, David S" sort="Siscovick, David S" uniqKey="Siscovick D" first="David S" last="Siscovick">David S. Siscovick</name><affiliation><nlm:affiliation>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, Washington 98101, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ruderfer, Douglas" sort="Ruderfer, Douglas" uniqKey="Ruderfer D" first="Douglas" last="Ruderfer">Douglas Ruderfer</name><affiliation><nlm:affiliation>Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Rochtchina, Elena" sort="Rochtchina, Elena" uniqKey="Rochtchina E" first="Elena" last="Rochtchina">Elena Rochtchina</name><affiliation><nlm:affiliation>Westmead Millennium Institute, Centre for Vision Research, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Atkinson, Elizabeth J" sort="Atkinson, Elizabeth J" uniqKey="Atkinson E" first="Elizabeth J" last="Atkinson">Elizabeth J. Atkinson</name><affiliation><nlm:affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Holliday, Elizabeth G" sort="Holliday, Elizabeth G" uniqKey="Holliday E" first="Elizabeth G" last="Holliday">Elizabeth G. Holliday</name><affiliation><nlm:affiliation>Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation><nlm:affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, 1200 Pressler St Suite 453E, Houston, Texas 77030, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Salvi, Erika" sort="Salvi, Erika" uniqKey="Salvi E" first="Erika" last="Salvi">Erika Salvi</name><affiliation><nlm:affiliation>Department of Health Sciences, University of Milano, Via Antonio di Rudinì 8, Milano 20142, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Bottinger, Erwin P" sort="Bottinger, Erwin P" uniqKey="Bottinger E" first="Erwin P" last="Bottinger">Erwin P. Bottinger</name><affiliation><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Murgia, Federico" sort="Murgia, Federico" uniqKey="Murgia F" first="Federico" last="Murgia">Federico Murgia</name><affiliation><nlm:affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation><nlm:affiliation>Department of Internal Medicine, Erasmus University Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Ernst, Florian" sort="Ernst, Florian" uniqKey="Ernst F" first="Florian" last="Ernst">Florian Ernst</name><affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kronenberg, Florian" sort="Kronenberg, Florian" uniqKey="Kronenberg F" first="Florian" last="Kronenberg">Florian Kronenberg</name><affiliation><nlm:affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Hu, Frank B" sort="Hu, Frank B" uniqKey="Hu F" first="Frank B" last="Hu">Frank B. Hu</name><affiliation><nlm:affiliation>Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Navis, Gerjan J" sort="Navis, Gerjan J" uniqKey="Navis G" first="Gerjan J" last="Navis">Gerjan J. Navis</name><affiliation><nlm:affiliation>Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Curhan, Gary C" sort="Curhan, Gary C" uniqKey="Curhan G" first="Gary C" last="Curhan">Gary C. Curhan</name><affiliation><nlm:affiliation>Brigham and Women's Hospital and Channing Laboratory, Harvard Medical School, 181 Longwood Avenue, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ehret, George B" sort="Ehret, George B" uniqKey="Ehret G" first="George B" last="Ehret">George B. Ehret</name><affiliation><nlm:affiliation>Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, Geneva 1205, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Coassin, Stefan" sort="Coassin, Stefan" uniqKey="Coassin S" first="Stefan" last="Coassin">Stefan Coassin</name><affiliation><nlm:affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Thun, Gian Andri" sort="Thun, Gian Andri" uniqKey="Thun G" first="Gian-Andri" last="Thun">Gian-Andri Thun</name><affiliation><nlm:affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><affiliation><nlm:affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Gambaro, Giovanni" sort="Gambaro, Giovanni" uniqKey="Gambaro G" first="Giovanni" last="Gambaro">Giovanni Gambaro</name><affiliation><nlm:affiliation>Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Via Moscati 31, Rome 00168, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Malerba, Giovanni" sort="Malerba, Giovanni" uniqKey="Malerba G" first="Giovanni" last="Malerba">Giovanni Malerba</name><affiliation><nlm:affiliation>Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, Verona 37134, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation><nlm:affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Jacobs, Gunnar" sort="Jacobs, Gunnar" uniqKey="Jacobs G" first="Gunnar" last="Jacobs">Gunnar Jacobs</name><affiliation><nlm:affiliation>Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Niemannsweg 11, Kiel 24105, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Guo" sort="Li, Guo" uniqKey="Li G" first="Guo" last="Li">Guo Li</name><affiliation><nlm:affiliation>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, Washington 98101, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, Neuherberg 85764, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation><nlm:affiliation>Austrian Stroke Prevention Study, Institute of Molecular Biology and Biochemistry, Department of Neurology, Medical University Graz, Harrachgasse 21, Graz 8010, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name><affiliation><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation><nlm:affiliation>Institute for Community Medicine, University of Greifswald, Walther-Rathenau-Strasse 48, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kroemer, Heyo K" sort="Kroemer, Heyo K" uniqKey="Kroemer H" first="Heyo K" last="Kroemer">Heyo K. Kroemer</name><affiliation><nlm:affiliation>Institute of Pharmacology, University of Greifswald, Friedrich-Loeffler-Straße 23d, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kramer, Holly" sort="Kramer, Holly" uniqKey="Kramer H" first="Holly" last="Kramer">Holly Kramer</name><affiliation><nlm:affiliation>Department of Public Health Sciences, Loyola Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lin, Honghuang" sort="Lin, Honghuang" uniqKey="Lin H" first="Honghuang" last="Lin">Honghuang Lin</name><affiliation><nlm:affiliation>Boston University School of Medicine, 72 East Concord Street, B-616, Boston, Massachusetts 02118, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Leach, I Mateo" sort="Leach, I Mateo" uniqKey="Leach I" first="I Mateo" last="Leach">I Mateo Leach</name><affiliation><nlm:affiliation>Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name><affiliation><nlm:affiliation>Robertson Centre for Biostatistics, University of Glasgow, R1122B Level 11, Robertson Centre, Boyd Orr Building, Glasgow G12 8QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Guessous, Idris" sort="Guessous, Idris" uniqKey="Guessous I" first="Idris" last="Guessous">Idris Guessous</name><affiliation><nlm:affiliation>Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation><nlm:affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Borecki, Ingrid" sort="Borecki, Ingrid" uniqKey="Borecki I" first="Ingrid" last="Borecki">Ingrid Borecki</name><affiliation><nlm:affiliation>Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Box 8506, St Louis, Missouri 63108, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M" last="Heid">Iris M. Heid</name><affiliation><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation><nlm:affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Persico, Ivana" sort="Persico, Ivana" uniqKey="Persico I" first="Ivana" last="Persico">Ivana Persico</name><affiliation><nlm:affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><affiliation><nlm:affiliation>Department of Cardiology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F" last="Felix">Janine F. Felix</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Divers, Jasmin" sort="Divers, Jasmin" uniqKey="Divers J" first="Jasmin" last="Divers">Jasmin Divers</name><affiliation><nlm:affiliation>Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University Health Sciences, 2326 Medical Center Boulevard, Winston-Salem, North Carolina 27157-1063, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lambert, Jean Charles" sort="Lambert, Jean Charles" uniqKey="Lambert J" first="Jean-Charles" last="Lambert">Jean-Charles Lambert</name><affiliation><nlm:affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</nlm:affiliation></affiliation></author><author><name sortKey="Stafford, Jeanette M" sort="Stafford, Jeanette M" uniqKey="Stafford J" first="Jeanette M" last="Stafford">Jeanette M. Stafford</name><affiliation><nlm:affiliation>Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University Health Sciences, 2326 Medical Center Boulevard, Winston-Salem, North Carolina 27157-1063, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gaspoz, Jean Michel" sort="Gaspoz, Jean Michel" uniqKey="Gaspoz J" first="Jean-Michel" last="Gaspoz">Jean-Michel Gaspoz</name><affiliation><nlm:affiliation>Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Smith, Jennifer A" sort="Smith, Jennifer A" uniqKey="Smith J" first="Jennifer A" last="Smith">Jennifer A. Smith</name><affiliation><nlm:affiliation>Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan 48109-2029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Faul, Jessica D" sort="Faul, Jessica D" uniqKey="Faul J" first="Jessica D" last="Faul">Jessica D. Faul</name><affiliation><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, 426 Thompson Street, #3456, Ann Arbor, Michigan 48104, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Jie Jin" sort="Wang, Jie Jin" uniqKey="Wang J" first="Jie Jin" last="Wang">Jie Jin Wang</name><affiliation><nlm:affiliation>Centre for Vision Research, Westmead Millennium Institute, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Ding, Jingzhong" sort="Ding, Jingzhong" uniqKey="Ding J" first="Jingzhong" last="Ding">Jingzhong Ding</name><affiliation><nlm:affiliation>Wake Forest School of Medicine, Department of Internal Medicine/Geriatrics, Medical center Boulevard, Winston-Salem, North Carolina 27157, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N" last="Hirschhorn">Joel N. Hirschhorn</name><affiliation><nlm:affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Attia, John" sort="Attia, John" uniqKey="Attia J" first="John" last="Attia">John Attia</name><affiliation><nlm:affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Whitfield, John B" sort="Whitfield, John B" uniqKey="Whitfield J" first="John B" last="Whitfield">John B. Whitfield</name><affiliation><nlm:affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Chalmers, John" sort="Chalmers, John" uniqKey="Chalmers J" first="John" last="Chalmers">John Chalmers</name><affiliation><nlm:affiliation>University of Sydney, The George Institute for Global Health, Level 10, King George V Building, 83-117 Missenden Road, Camperdown, New South Wales 2050, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Viikari, Jorma" sort="Viikari, Jorma" uniqKey="Viikari J" first="Jorma" last="Viikari">Jorma Viikari</name><affiliation><nlm:affiliation>Department of Medicine, University of Turku, Turku University Hospital, PO Box 52, Turku 20521, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Coresh, Josef" sort="Coresh, Josef" uniqKey="Coresh J" first="Josef" last="Coresh">Josef Coresh</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Denny, Joshua C" sort="Denny, Joshua C" uniqKey="Denny J" first="Joshua C" last="Denny">Joshua C. Denny</name><affiliation><nlm:affiliation>Vanderbilt University School of Medicine, 448 Eskind Biomedical Library, 2209 Garland Avenue, Nashville, Tennessee 37212, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Karjalainen, Juha" sort="Karjalainen, Juha" uniqKey="Karjalainen J" first="Juha" last="Karjalainen">Juha Karjalainen</name><affiliation><nlm:affiliation>Department of Genetics, University of Groningen, University Medical Centre Groningen, PO Box 72, Groningen 9700 AB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Fernandes, Jyotika K" sort="Fernandes, Jyotika K" uniqKey="Fernandes J" first="Jyotika K" last="Fernandes">Jyotika K. Fernandes</name><affiliation><nlm:affiliation>Division of Endocrinology, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Endlich, Karlhans" sort="Endlich, Karlhans" uniqKey="Endlich K" first="Karlhans" last="Endlich">Karlhans Endlich</name><affiliation><nlm:affiliation>Institute of Anatomy and Cell Biology, University of Greifswald, Friedrich-Loeffler-Straße 23c, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Butterbach, Katja" sort="Butterbach, Katja" uniqKey="Butterbach K" first="Katja" last="Butterbach">Katja Butterbach</name><affiliation><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Keene, Keith L" sort="Keene, Keith L" uniqKey="Keene K" first="Keith L" last="Keene">Keith L. Keene</name><affiliation><nlm:affiliation>Center for Health Disparities, Department of Biology, East Carolina University, 1001 East 10th Street, N209 Howell Science Complex Mailstop 551, Greenville, North Carolina 27858, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lohman, Kurt" sort="Lohman, Kurt" uniqKey="Lohman K" first="Kurt" last="Lohman">Kurt Lohman</name><affiliation><nlm:affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Portas, Laura" sort="Portas, Laura" uniqKey="Portas L" first="Laura" last="Portas">Laura Portas</name><affiliation><nlm:affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation><nlm:affiliation>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Gateway Building, 3C309, 7201 Winsconsin Avenue, Bethesda, Maryland 20892-9205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lyytik Inen, Leo Pekka" sort="Lyytik Inen, Leo Pekka" uniqKey="Lyytik Inen L" first="Leo-Pekka" last="Lyytik Inen">Leo-Pekka Lyytik Inen</name><affiliation><nlm:affiliation>Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere 33520, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loic" last="Yengo">Loic Yengo</name><affiliation><nlm:affiliation>CNRS UMR 8199, 1 Rue du Professeur Calmette, Lille 59000, France.</nlm:affiliation></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation><nlm:affiliation>Department of Genetics, University of Groningen, University Medical Centre Groningen, PO Box 72, Groningen 9700 AB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation><nlm:affiliation>Clinical Research Branch, National Institute on Aging, 251 Bayview Blvd, Baltimore, Maryland 21250, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name><affiliation><nlm:affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kedenko, Lyudmyla" sort="Kedenko, Lyudmyla" uniqKey="Kedenko L" first="Lyudmyla" last="Kedenko">Lyudmyla Kedenko</name><affiliation><nlm:affiliation>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Müllner Hauptstraße 48, Salzburg 5020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Rao, Madhumathi" sort="Rao, Madhumathi" uniqKey="Rao M" first="Madhumathi" last="Rao">Madhumathi Rao</name><affiliation><nlm:affiliation>Division of Nephrology/Tufts Evidence Practice Center, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Struchalin, Maksim" sort="Struchalin, Maksim" uniqKey="Struchalin M" first="Maksim" last="Struchalin">Maksim Struchalin</name><affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Dr Molewaterplein, Rotterdam 50-603015 GE, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Kleber, Marcus E" sort="Kleber, Marcus E" uniqKey="Kleber M" first="Marcus E" last="Kleber">Marcus E. Kleber</name><affiliation><nlm:affiliation>Medical Clinic V, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Cavalieri, Margherita" sort="Cavalieri, Margherita" uniqKey="Cavalieri M" first="Margherita" last="Cavalieri">Margherita Cavalieri</name><affiliation><nlm:affiliation>Austrian Stroke Prevention Study, Department of Neurology, Division of Special Neurology, Medical University Graz, Auenbruggerplatz 22, Graz 8036, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Haun, Margot" sort="Haun, Margot" uniqKey="Haun M" first="Margot" last="Haun">Margot Haun</name><affiliation><nlm:affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Cornelis, Marilyn C" sort="Cornelis, Marilyn C" uniqKey="Cornelis M" first="Marilyn C" last="Cornelis">Marilyn C. Cornelis</name><affiliation><nlm:affiliation>Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ciullo, Marina" sort="Ciullo, Marina" uniqKey="Ciullo M" first="Marina" last="Ciullo">Marina Ciullo</name><affiliation><nlm:affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pirastu, Mario" sort="Pirastu, Mario" uniqKey="Pirastu M" first="Mario" last="Pirastu">Mario Pirastu</name><affiliation><nlm:affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="De Andrade, Mariza" sort="De Andrade, Mariza" uniqKey="De Andrade M" first="Mariza" last="De Andrade">Mariza De Andrade</name><affiliation><nlm:affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mcevoy, Mark A" sort="Mcevoy, Mark A" uniqKey="Mcevoy M" first="Mark A" last="Mcevoy">Mark A. Mcevoy</name><affiliation><nlm:affiliation>Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, HRMC, New South Wales 2310, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Woodward, Mark" sort="Woodward, Mark" uniqKey="Woodward M" first="Mark" last="Woodward">Mark Woodward</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Adam, Martin" sort="Adam, Martin" uniqKey="Adam M" first="Martin" last="Adam">Martin Adam</name><affiliation><nlm:affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Cocca, Massimiliano" sort="Cocca, Massimiliano" uniqKey="Cocca M" first="Massimiliano" last="Cocca">Massimiliano Cocca</name><affiliation><nlm:affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Nauck, Matthias" sort="Nauck, Matthias" uniqKey="Nauck M" first="Matthias" last="Nauck">Matthias Nauck</name><affiliation><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Imboden, Medea" sort="Imboden, Medea" uniqKey="Imboden M" first="Medea" last="Imboden">Medea Imboden</name><affiliation><nlm:affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name><affiliation><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Pruijm, Menno" sort="Pruijm, Menno" uniqKey="Pruijm M" first="Menno" last="Pruijm">Menno Pruijm</name><affiliation><nlm:affiliation>Service of Nephrology, Lausanne University Hospital, Rue du Bugnon 17, Lausanne 1005, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Metzger, Marie" sort="Metzger, Marie" uniqKey="Metzger M" first="Marie" last="Metzger">Marie Metzger</name><affiliation><nlm:affiliation>Inserm UMRS 1018, CESP Team 10, Université Paris-Sud, 16 avenue Paul Vaillant Couturier, Villejuif 94807, France.</nlm:affiliation></affiliation></author><author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><affiliation><nlm:affiliation>Department of Medicine, University of Leipzig, Liebigstraße 18, Leipzig 04103, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Evans, Michele K" sort="Evans, Michele K" uniqKey="Evans M" first="Michele K" last="Evans">Michele K. Evans</name><affiliation><nlm:affiliation>Health Disparities Research Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, NIH Biomedical Center, 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sale, Michele M" sort="Sale, Michele M" uniqKey="Sale M" first="Michele M" last="Sale">Michele M. Sale</name><affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Medicine (Cardiovascular Medicine), University of Virginia, PO Box 800717, Charlottesville, Virginia 22908, USA.</nlm:affiliation></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation><nlm:affiliation>Department of Clinical Physiology, Tampere University Hospital, University of Tampere, School of Medicine, Tampere 33521, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name><affiliation><nlm:affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Bochud, Murielle" sort="Bochud, Murielle" uniqKey="Bochud M" first="Murielle" last="Bochud">Murielle Bochud</name><affiliation><nlm:affiliation>University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Route de la Corniche 2, Epalinges CH-1066, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Rheinberger, Myriam" sort="Rheinberger, Myriam" uniqKey="Rheinberger M" first="Myriam" last="Rheinberger">Myriam Rheinberger</name><affiliation><nlm:affiliation>Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation><nlm:affiliation>Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Bouatia Naji, Nabila" sort="Bouatia Naji, Nabila" uniqKey="Bouatia Naji N" first="Nabila" last="Bouatia-Naji">Nabila Bouatia-Naji</name><affiliation><nlm:affiliation>INSERM UMR970, Paris Cardiovascular Research Center (PARCC), 56 rue Leblanc, Paris F-75015, France.</nlm:affiliation></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation><nlm:affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Hastie, Nick" sort="Hastie, Nick" uniqKey="Hastie N" first="Nick" last="Hastie">Nick Hastie</name><affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Probst Hensch, Nicole" sort="Probst Hensch, Nicole" uniqKey="Probst Hensch N" first="Nicole" last="Probst-Hensch">Nicole Probst-Hensch</name><affiliation><nlm:affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name><affiliation><nlm:affiliation>Wellcome Trust Sanger Institute, Hinxton CB10 1HH, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Devuyst, Olivier" sort="Devuyst, Olivier" uniqKey="Devuyst O" first="Olivier" last="Devuyst">Olivier Devuyst</name><affiliation><nlm:affiliation>University of Zurich, Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, Winterthurerstrasse 190, Zürich 8057, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Raitakari, Olli" sort="Raitakari, Olli" uniqKey="Raitakari O" first="Olli" last="Raitakari">Olli Raitakari</name><affiliation><nlm:affiliation>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku University Hospital, Department of Clinical Physiology, PO Box 52, Turku 20521, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Gottesman, Omri" sort="Gottesman, Omri" uniqKey="Gottesman O" first="Omri" last="Gottesman">Omri Gottesman</name><affiliation><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H" last="Franco">Oscar H. Franco</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name><affiliation><nlm:affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Gasparini, Paolo" sort="Gasparini, Paolo" uniqKey="Gasparini P" first="Paolo" last="Gasparini">Paolo Gasparini</name><affiliation><nlm:affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Munroe, Patricia B" sort="Munroe, Patricia B" uniqKey="Munroe P" first="Patricia B" last="Munroe">Patricia B. Munroe</name><affiliation><nlm:affiliation>Department Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><affiliation><nlm:affiliation>Harvard Medical School, 900 Commonwealth Avenue East, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mitchell, Paul" sort="Mitchell, Paul" uniqKey="Mitchell P" first="Paul" last="Mitchell">Paul Mitchell</name><affiliation><nlm:affiliation>Centre for Vision Research, Westmead Millennium Institute, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Muntner, Paul" sort="Muntner, Paul" uniqKey="Muntner P" first="Paul" last="Muntner">Paul Muntner</name><affiliation><nlm:affiliation>University of Alabama at Birmingham, Department of Medicine, 1530 3rd Avenue, South Birmingham, Alabama 35294-0022, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Meisinger, Christa" sort="Meisinger, Christa" uniqKey="Meisinger C" first="Christa" last="Meisinger">Christa Meisinger</name><affiliation><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Smit, Johannes H" sort="Smit, Johannes H" uniqKey="Smit J" first="Johannes H" last="Smit">Johannes H. Smit</name><affiliation><nlm:affiliation>Department of Psychiatry and EMGO+ Institute, VU University Medical Center, A.J. Ernststraat 1187, Amsterdam 1081 HL, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name><affiliation><nlm:affiliation>IFB AdiposityDiseases, University of Leipzig, Liebigstraße 21, Leipzig 04103, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wild, Philipp S" sort="Wild, Philipp S" uniqKey="Wild P" first="Philipp S" last="Wild">Philipp S. Wild</name><affiliation><nlm:affiliation>Medical University Center Mainz, Langenbeckstraße 1, Mainz 55131, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation><nlm:affiliation>CNRS UMR 8199, 1 Rue du Professeur Calmette, Lille 59000, France.</nlm:affiliation></affiliation></author><author><name sortKey="Rettig, Rainer" sort="Rettig, Rainer" uniqKey="Rettig R" first="Rainer" last="Rettig">Rainer Rettig</name><affiliation><nlm:affiliation>Institute of Physiology, University of Greifswald, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation><nlm:affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</nlm:affiliation></affiliation></author><author><name sortKey="Biffar, Reiner" sort="Biffar, Reiner" uniqKey="Biffar R" first="Reiner" last="Biffar">Reiner Biffar</name><affiliation><nlm:affiliation>Clinic for Prosthodontic Dentistry, Gerostomatology and Material Science, University of Greifswald, Rotgerberstraße 8, Greifswald 17475, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><affiliation><nlm:affiliation>Austrian Stroke Prevention Study, Department of Neurology, Division of Special Neurology, Medical University Graz, Auenbruggerplatz 22, Graz 8036, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Middelberg, Rita P S" sort="Middelberg, Rita P S" uniqKey="Middelberg R" first="Rita P S" last="Middelberg">Rita P S. Middelberg</name><affiliation><nlm:affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Carroll, Robert J" sort="Carroll, Robert J" uniqKey="Carroll R" first="Robert J" last="Carroll">Robert J. Carroll</name><affiliation><nlm:affiliation>Vanderbilt University School of Medicine, 448 Eskind Biomedical Library, 2209 Garland Avenue, Nashville, Tennessee 37212, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><affiliation><nlm:affiliation>Department of Psychiatry and EMGO+ Institute, VU University Medical Center, A.J. Ernststraat 1187, Amsterdam 1081 HL, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Scott, Rodney J" sort="Scott, Rodney J" uniqKey="Scott R" first="Rodney J" last="Scott">Rodney J. Scott</name><affiliation><nlm:affiliation>School of Biomedical Sciences and Pharmacy, University of Newcastle, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, HRMC, New South Wales 2310, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Katz, Ronit" sort="Katz, Ronit" uniqKey="Katz R" first="Ronit" last="Katz">Ronit Katz</name><affiliation><nlm:affiliation>Kidney Research Institute, University of Washington, Box 359606, 325 9th Avenue, Seattle, Washington 98104, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sedaghat, Sanaz" sort="Sedaghat, Sanaz" uniqKey="Sedaghat S" first="Sanaz" last="Sedaghat">Sanaz Sedaghat</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><affiliation><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L R" last="Kardia">Sharon L R. Kardia</name><affiliation><nlm:affiliation>Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan 48109-2029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ulivi, Sheila" sort="Ulivi, Sheila" uniqKey="Ulivi S" first="Sheila" last="Ulivi">Sheila Ulivi</name><affiliation><nlm:affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Via dell'Istria 65, Trieste 34137, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><affiliation><nlm:affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Enroth, Stefan" sort="Enroth, Stefan" uniqKey="Enroth S" first="Stefan" last="Enroth">Stefan Enroth</name><affiliation><nlm:affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Kloiber, Stefan" sort="Kloiber, Stefan" uniqKey="Kloiber S" first="Stefan" last="Kloiber">Stefan Kloiber</name><affiliation><nlm:affiliation>Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, Munich 80804, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><affiliation><nlm:affiliation>Department of Cardiology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Stengel, Benedicte" sort="Stengel, Benedicte" uniqKey="Stengel B" first="Benedicte" last="Stengel">Benedicte Stengel</name><affiliation><nlm:affiliation>Inserm UMRS 1018, CESP Team 10, Université Paris-Sud, 16 avenue Paul Vaillant Couturier, Villejuif 94807, France.</nlm:affiliation></affiliation></author><author><name sortKey="Hancock, Stephen J" sort="Hancock, Stephen J" uniqKey="Hancock S" first="Stephen J" last="Hancock">Stephen J. Hancock</name><affiliation><nlm:affiliation>Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Turner, Stephen T" sort="Turner, Stephen T" uniqKey="Turner S" first="Stephen T" last="Turner">Stephen T. Turner</name><affiliation><nlm:affiliation>Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Rosas, Sylvia E" sort="Rosas, Sylvia E" uniqKey="Rosas S" first="Sylvia E" last="Rosas">Sylvia E. Rosas</name><affiliation><nlm:affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Stracke, Sylvia" sort="Stracke, Sylvia" uniqKey="Stracke S" first="Sylvia" last="Stracke">Sylvia Stracke</name><affiliation><nlm:affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</nlm:affiliation></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation><nlm:affiliation>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Gateway Building, 3C309, 7201 Winsconsin Avenue, Bethesda, Maryland 20892-9205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Zeller, Tanja" sort="Zeller, Tanja" uniqKey="Zeller T" first="Tanja" last="Zeller">Tanja Zeller</name><affiliation><nlm:affiliation>University Heart Center Hamburg, Clinic for general and interventional cardiology, Martinistraße 52, Hamburg 20246, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name><affiliation><nlm:affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation><nlm:affiliation>Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere 33520, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><affiliation><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Nikopensius, Tiit" sort="Nikopensius, Tiit" uniqKey="Nikopensius T" first="Tiit" last="Nikopensius">Tiit Nikopensius</name><affiliation><nlm:affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</nlm:affiliation></affiliation></author><author><name sortKey="Esko, Tonu" sort="Esko, Tonu" uniqKey="Esko T" first="Tonu" last="Esko">Tonu Esko</name><affiliation><nlm:affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation><nlm:affiliation>Clinical Research Branch, National Institute on Aging, 251 Bayview Blvd, Baltimore, Maryland 21250, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gyllensten, Ulf" sort="Gyllensten, Ulf" uniqKey="Gyllensten U" first="Ulf" last="Gyllensten">Ulf Gyllensten</name><affiliation><nlm:affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name><affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Emilsson, Valur" sort="Emilsson, Valur" uniqKey="Emilsson V" first="Valur" last="Emilsson">Valur Emilsson</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Aalto, Ville" sort="Aalto, Ville" uniqKey="Aalto V" first="Ville" last="Aalto">Ville Aalto</name><affiliation><nlm:affiliation>Department of Clinical Physiology, Turku University Hospital, Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, PO Box 52, Turku 20521, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><affiliation><nlm:affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, Wei Min" sort="Chen, Wei Min" uniqKey="Chen W" first="Wei-Min" last="Chen">Wei-Min Chen</name><affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Medicine (Cardiovascular Medicine), University of Virginia, PO Box 800717, Charlottesville, Virginia 22908, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Igl, Wilmar" sort="Igl, Wilmar" uniqKey="Igl W" first="Wilmar" last="Igl">Wilmar Igl</name><affiliation><nlm:affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="M Rz, Winfried" sort="M Rz, Winfried" uniqKey="M Rz W" first="Winfried" last="M Rz">Winfried M Rz</name><affiliation><nlm:affiliation>Synlab Academy, Synlab Services GmbH, Oberer Eselsberg 45, Ulm 89081, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name><affiliation><nlm:affiliation>Department of Internal Medicine II-Cardiology, University of Ulm Medical Centre, Albert-Einstein-Allee 23, Ulm 89081, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Lieb, Wolfgang" sort="Lieb, Wolfgang" uniqKey="Lieb W" first="Wolfgang" last="Lieb">Wolfgang Lieb</name><affiliation><nlm:affiliation>Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Niemannsweg 11, Kiel 24105, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><affiliation><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation><nlm:affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation><nlm:affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Pramstaller, Peter P" sort="Pramstaller, Peter P" uniqKey="Pramstaller P" first="Peter P" last="Pramstaller">Peter P. Pramstaller</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Parsa, Afshin" sort="Parsa, Afshin" uniqKey="Parsa A" first="Afshin" last="Parsa">Afshin Parsa</name><affiliation><nlm:affiliation>University of Maryland Medical School, Division of Nephrology, 685 W. Baltimore Street, MSTF 314, Baltimore, Maryland 21201, USA.</nlm:affiliation></affiliation></author><author><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R" last="O'Connell">Jeffrey R. O'Connell</name><affiliation><nlm:affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Susztak, Katalin" sort="Susztak, Katalin" uniqKey="Susztak K" first="Katalin" last="Susztak">Katalin Susztak</name><affiliation><nlm:affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hamet, Pavel" sort="Hamet, Pavel" uniqKey="Hamet P" first="Pavel" last="Hamet">Pavel Hamet</name><affiliation><nlm:affiliation>CRCHUM, University of Montreal, CHUM Research Center, Technopôle Angus, 900 Saint-Denis, Montreal, Québec, Canada H2X 0A9.</nlm:affiliation></affiliation></author><author><name sortKey="Tremblay, Johanne" sort="Tremblay, Johanne" uniqKey="Tremblay J" first="Johanne" last="Tremblay">Johanne Tremblay</name><affiliation><nlm:affiliation>CRCHUM, University of Montreal, CHUM Research Center, Technopôle Angus, 900 Saint-Denis, Montreal, Québec, Canada H2X 0A9.</nlm:affiliation></affiliation></author><author><name sortKey="De Boer, Ian H" sort="De Boer, Ian H" uniqKey="De Boer I" first="Ian H" last="De Boer">Ian H. De Boer</name><affiliation><nlm:affiliation>Kidney Research Institute, University of Washington, Box 359606, 325 9th Avenue, Seattle, Washington 98104, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Boger, Carsten A" sort="Boger, Carsten A" uniqKey="Boger C" first="Carsten A" last="Böger">Carsten A. Böger</name><affiliation><nlm:affiliation>Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Goessling, Wolfram" sort="Goessling, Wolfram" uniqKey="Goessling W" first="Wolfram" last="Goessling">Wolfram Goessling</name><affiliation><nlm:affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, New Research Building77 Avenue Louis Pasteur, Room 458, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><affiliation><nlm:affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kottgen, Anna" sort="Kottgen, Anna" uniqKey="Kottgen A" first="Anna" last="Köttgen">Anna Köttgen</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kao, W H Linda" sort="Kao, W H Linda" uniqKey="Kao W" first="W H Linda" last="Kao">W H Linda Kao</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S" last="Fox">Caroline S. Fox</name><affiliation><nlm:affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26831199</idno><idno type="pmid">26831199</idno><idno type="doi">10.1038/ncomms10023</idno><idno type="wicri:Area/PubMed/Corpus">002466</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002466</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.</title><author><name sortKey="Pattaro, Cristian" sort="Pattaro, Cristian" uniqKey="Pattaro C" first="Cristian" last="Pattaro">Cristian Pattaro</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name><affiliation><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Chu, Audrey Y" sort="Chu, Audrey Y" uniqKey="Chu A" first="Audrey Y" last="Chu">Audrey Y. Chu</name><affiliation><nlm:affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mijatovic, Vladan" sort="Mijatovic, Vladan" uniqKey="Mijatovic V" first="Vladan" last="Mijatovic">Vladan Mijatovic</name><affiliation><nlm:affiliation>Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, Verona 37134, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Garnaas, Maija" sort="Garnaas, Maija" uniqKey="Garnaas M" first="Maija" last="Garnaas">Maija Garnaas</name><affiliation><nlm:affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, New Research Building77 Avenue Louis Pasteur, Room 458, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Tin, Adrienne" sort="Tin, Adrienne" uniqKey="Tin A" first="Adrienne" last="Tin">Adrienne Tin</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sorice, Rossella" sort="Sorice, Rossella" uniqKey="Sorice R" first="Rossella" last="Sorice">Rossella Sorice</name><affiliation><nlm:affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name><affiliation><nlm:affiliation>Department of Internal Medicine IV, University Hospital Freiburg, Berliner Allee 29, Freiburg 79110, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Taliun, Daniel" sort="Taliun, Daniel" uniqKey="Taliun D" first="Daniel" last="Taliun">Daniel Taliun</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Olden, Matthias" sort="Olden, Matthias" uniqKey="Olden M" first="Matthias" last="Olden">Matthias Olden</name><affiliation><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Foster, Meredith" sort="Foster, Meredith" uniqKey="Foster M" first="Meredith" last="Foster">Meredith Foster</name><affiliation><nlm:affiliation>Division of Nephrology/Tufts Evidence Practice Center, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Yang, Qiong" sort="Yang, Qiong" uniqKey="Yang Q" first="Qiong" last="Yang">Qiong Yang</name><affiliation><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, Massachusetts 02118, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, Ming Huei" sort="Chen, Ming Huei" uniqKey="Chen M" first="Ming-Huei" last="Chen">Ming-Huei Chen</name><affiliation><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, Massachusetts 02118, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H" last="Pers">Tune H. Pers</name><affiliation><nlm:affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D" last="Johnson">Andrew D. Johnson</name><affiliation><nlm:affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ko, Yi An" sort="Ko, Yi An" uniqKey="Ko Y" first="Yi-An" last="Ko">Yi-An Ko</name><affiliation><nlm:affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Fuchsberger, Christian" sort="Fuchsberger, Christian" uniqKey="Fuchsberger C" first="Christian" last="Fuchsberger">Christian Fuchsberger</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Tayo, Bamidele" sort="Tayo, Bamidele" uniqKey="Tayo B" first="Bamidele" last="Tayo">Bamidele Tayo</name><affiliation><nlm:affiliation>Department of Public Health Sciences, Loyola Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Nalls, Michael" sort="Nalls, Michael" uniqKey="Nalls M" first="Michael" last="Nalls">Michael Nalls</name><affiliation><nlm:affiliation>Laboratory of Neurogenetics, Building 35-Porter Building, 1A1015, National Institute on Aging/NIH, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F" last="Feitosa">Mary F. Feitosa</name><affiliation><nlm:affiliation>Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Box 8506, St Louis, Missouri 63108, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Isaacs, Aaron" sort="Isaacs, Aaron" uniqKey="Isaacs A" first="Aaron" last="Isaacs">Aaron Isaacs</name><affiliation><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="D Adamo, Pio" sort="D Adamo, Pio" uniqKey="D Adamo P" first="Pio" last="D'Adamo">Pio D'Adamo</name><affiliation><nlm:affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Adeyemo, Adebowale" sort="Adeyemo, Adebowale" uniqKey="Adeyemo A" first="Adebowale" last="Adeyemo">Adebowale Adeyemo</name><affiliation><nlm:affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Dieffenbach, Aida Karina" sort="Dieffenbach, Aida Karina" uniqKey="Dieffenbach A" first="Aida Karina" last="Dieffenbach">Aida Karina Dieffenbach</name><affiliation><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Zonderman, Alan B" sort="Zonderman, Alan B" uniqKey="Zonderman A" first="Alan B" last="Zonderman">Alan B. Zonderman</name><affiliation><nlm:affiliation>Laboratory of Personality and Cognition, National Institute on Aging, National Institutes of Health, NIH Biomedical Center, 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><affiliation><nlm:affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Most, Peter J" sort="Van Der Most, Peter J" uniqKey="Van Der Most P" first="Peter J" last="Van Der Most">Peter J. Van Der Most</name><affiliation><nlm:affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><affiliation><nlm:affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name><affiliation><nlm:affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, 1200 Pressler St Suite 453E, Houston, Texas 77030, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Dreisbach, Albert W" sort="Dreisbach, Albert W" uniqKey="Dreisbach A" first="Albert W" last="Dreisbach">Albert W. Dreisbach</name><affiliation><nlm:affiliation>Division of Nephrology, University of Mississippi, 2500 North State Street, Jackson, Mississippi 39216, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name><affiliation><nlm:affiliation>Institute of Clinical Molecular Biology, Christian-Albrechts University of Kiel, Schittenhelmstraße 12, Kiel 24105, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name><affiliation><nlm:affiliation>Department of Internal Medicine, Erasmus University Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation><nlm:affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</nlm:affiliation></affiliation></author><author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tonjes">Anke Tonjes</name><affiliation><nlm:affiliation>Department of Medicine, University of Leipzig, Liebigstraße 18, Leipzig 04103, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Lupo, Antonio" sort="Lupo, Antonio" uniqKey="Lupo A" first="Antonio" last="Lupo">Antonio Lupo</name><affiliation><nlm:affiliation>Division of Nephrology, Department of Medicine, University of Verona, Piazzale Aristide Stefani 1, Verona 37126, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Robino, Antonietta" sort="Robino, Antonietta" uniqKey="Robino A" first="Antonietta" last="Robino">Antonietta Robino</name><affiliation><nlm:affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Johansson, Sa" sort="Johansson, Sa" uniqKey="Johansson " first=" Sa" last="Johansson"> Sa Johansson</name><affiliation><nlm:affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Demirkan, Ayse" sort="Demirkan, Ayse" uniqKey="Demirkan A" first="Ayse" last="Demirkan">Ayse Demirkan</name><affiliation><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Kollerits, Barbara" sort="Kollerits, Barbara" uniqKey="Kollerits B" first="Barbara" last="Kollerits">Barbara Kollerits</name><affiliation><nlm:affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Freedman, Barry I" sort="Freedman, Barry I" uniqKey="Freedman B" first="Barry I" last="Freedman">Barry I. Freedman</name><affiliation><nlm:affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ponte, Belen" sort="Ponte, Belen" uniqKey="Ponte B" first="Belen" last="Ponte">Belen Ponte</name><affiliation><nlm:affiliation>Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospital, 4 rue Gabrielle-Perret-Gentil, Geneve 1211, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Paulweber, Bernhard" sort="Paulweber, Bernhard" uniqKey="Paulweber B" first="Bernhard" last="Paulweber">Bernhard Paulweber</name><affiliation><nlm:affiliation>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Müllner Hauptstraße 48, Salzburg 5020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Kr Mer, Bernhard K" sort="Kr Mer, Bernhard K" uniqKey="Kr Mer B" first="Bernhard K" last="Kr Mer">Bernhard K. Kr Mer</name><affiliation><nlm:affiliation>University Medical Centre Mannheim, 5th Department of Medicine, University of Heidelberg, Theodor Kutzer Ufer 1-3, Mannheim 68167, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Mitchell, Braxton D" sort="Mitchell, Braxton D" uniqKey="Mitchell B" first="Braxton D" last="Mitchell">Braxton D. Mitchell</name><affiliation><nlm:affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Buckley, Brendan M" sort="Buckley, Brendan M" uniqKey="Buckley B" first="Brendan M" last="Buckley">Brendan M. Buckley</name><affiliation><nlm:affiliation>Department of Pharmacology and Therapeutics, University College Cork, Clinical Investigations Building, Western Rd, Cork, Ireland.</nlm:affiliation></affiliation></author><author><name sortKey="Peralta, Carmen A" sort="Peralta, Carmen A" uniqKey="Peralta C" first="Carmen A" last="Peralta">Carmen A. Peralta</name><affiliation><nlm:affiliation>Division of Nephrology, University of California, San Francisco Medical School and San Francisco VA Medical Center, 4150 Clement Street, San Francisco, California 94121, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Helmer, Catherine" sort="Helmer, Catherine" uniqKey="Helmer C" first="Catherine" last="Helmer">Catherine Helmer</name><affiliation><nlm:affiliation>INSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux F-33000, France.</nlm:affiliation></affiliation></author><author><name sortKey="Rotimi, Charles N" sort="Rotimi, Charles N" uniqKey="Rotimi C" first="Charles N" last="Rotimi">Charles N. Rotimi</name><affiliation><nlm:affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Shaffer, Christian M" sort="Shaffer, Christian M" uniqKey="Shaffer C" first="Christian M" last="Shaffer">Christian M. Shaffer</name><affiliation><nlm:affiliation>Vanderbilt University School of Medicine, 2215-B Garland Avenue 1224-MRB4 (Light Hall)Nashville, Tennessee 37232, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Muller, Christian" sort="Muller, Christian" uniqKey="Muller C" first="Christian" last="Müller">Christian Müller</name><affiliation><nlm:affiliation>University Heart Center Hamburg, Clinic for general and interventional cardiology, Martinistraße 52, Hamburg 20246, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Sala, Cinzia" sort="Sala, Cinzia" uniqKey="Sala C" first="Cinzia" last="Sala">Cinzia Sala</name><affiliation><nlm:affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Saint Pierre, Aude" sort="Saint Pierre, Aude" uniqKey="Saint Pierre A" first="Aude" last="Saint-Pierre">Aude Saint-Pierre</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ackermann, Daniel" sort="Ackermann, Daniel" uniqKey="Ackermann D" first="Daniel" last="Ackermann">Daniel Ackermann</name><affiliation><nlm:affiliation>Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospital, 4 rue Gabrielle-Perret-Gentil, Geneve 1211, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Shriner, Daniel" sort="Shriner, Daniel" uniqKey="Shriner D" first="Daniel" last="Shriner">Daniel Shriner</name><affiliation><nlm:affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ruggiero, Daniela" sort="Ruggiero, Daniela" uniqKey="Ruggiero D" first="Daniela" last="Ruggiero">Daniela Ruggiero</name><affiliation><nlm:affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Toniolo, Daniela" sort="Toniolo, Daniela" uniqKey="Toniolo D" first="Daniela" last="Toniolo">Daniela Toniolo</name><affiliation><nlm:affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Lu, Yingchang" sort="Lu, Yingchang" uniqKey="Lu Y" first="Yingchang" last="Lu">Yingchang Lu</name><affiliation><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation><nlm:affiliation>Department of Health Sciences, University of Milano, Via Antonio di Rudinì 8, Milano 20142, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Czamara, Darina" sort="Czamara, Darina" uniqKey="Czamara D" first="Darina" last="Czamara">Darina Czamara</name><affiliation><nlm:affiliation>Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, Munich 80804, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Ellinghaus, David" sort="Ellinghaus, David" uniqKey="Ellinghaus D" first="David" last="Ellinghaus">David Ellinghaus</name><affiliation><nlm:affiliation>Institute of Clinical Molecular Biology, Christian-Albrechts University of Kiel, Schittenhelmstraße 12, Kiel 24105, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Siscovick, David S" sort="Siscovick, David S" uniqKey="Siscovick D" first="David S" last="Siscovick">David S. Siscovick</name><affiliation><nlm:affiliation>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, Washington 98101, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ruderfer, Douglas" sort="Ruderfer, Douglas" uniqKey="Ruderfer D" first="Douglas" last="Ruderfer">Douglas Ruderfer</name><affiliation><nlm:affiliation>Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Rochtchina, Elena" sort="Rochtchina, Elena" uniqKey="Rochtchina E" first="Elena" last="Rochtchina">Elena Rochtchina</name><affiliation><nlm:affiliation>Westmead Millennium Institute, Centre for Vision Research, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Atkinson, Elizabeth J" sort="Atkinson, Elizabeth J" uniqKey="Atkinson E" first="Elizabeth J" last="Atkinson">Elizabeth J. Atkinson</name><affiliation><nlm:affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Holliday, Elizabeth G" sort="Holliday, Elizabeth G" uniqKey="Holliday E" first="Elizabeth G" last="Holliday">Elizabeth G. Holliday</name><affiliation><nlm:affiliation>Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation><nlm:affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, 1200 Pressler St Suite 453E, Houston, Texas 77030, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Salvi, Erika" sort="Salvi, Erika" uniqKey="Salvi E" first="Erika" last="Salvi">Erika Salvi</name><affiliation><nlm:affiliation>Department of Health Sciences, University of Milano, Via Antonio di Rudinì 8, Milano 20142, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Bottinger, Erwin P" sort="Bottinger, Erwin P" uniqKey="Bottinger E" first="Erwin P" last="Bottinger">Erwin P. Bottinger</name><affiliation><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Murgia, Federico" sort="Murgia, Federico" uniqKey="Murgia F" first="Federico" last="Murgia">Federico Murgia</name><affiliation><nlm:affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation><nlm:affiliation>Department of Internal Medicine, Erasmus University Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Ernst, Florian" sort="Ernst, Florian" uniqKey="Ernst F" first="Florian" last="Ernst">Florian Ernst</name><affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kronenberg, Florian" sort="Kronenberg, Florian" uniqKey="Kronenberg F" first="Florian" last="Kronenberg">Florian Kronenberg</name><affiliation><nlm:affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Hu, Frank B" sort="Hu, Frank B" uniqKey="Hu F" first="Frank B" last="Hu">Frank B. Hu</name><affiliation><nlm:affiliation>Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Navis, Gerjan J" sort="Navis, Gerjan J" uniqKey="Navis G" first="Gerjan J" last="Navis">Gerjan J. Navis</name><affiliation><nlm:affiliation>Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Curhan, Gary C" sort="Curhan, Gary C" uniqKey="Curhan G" first="Gary C" last="Curhan">Gary C. Curhan</name><affiliation><nlm:affiliation>Brigham and Women's Hospital and Channing Laboratory, Harvard Medical School, 181 Longwood Avenue, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ehret, George B" sort="Ehret, George B" uniqKey="Ehret G" first="George B" last="Ehret">George B. Ehret</name><affiliation><nlm:affiliation>Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, Geneva 1205, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Coassin, Stefan" sort="Coassin, Stefan" uniqKey="Coassin S" first="Stefan" last="Coassin">Stefan Coassin</name><affiliation><nlm:affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Thun, Gian Andri" sort="Thun, Gian Andri" uniqKey="Thun G" first="Gian-Andri" last="Thun">Gian-Andri Thun</name><affiliation><nlm:affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><affiliation><nlm:affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Gambaro, Giovanni" sort="Gambaro, Giovanni" uniqKey="Gambaro G" first="Giovanni" last="Gambaro">Giovanni Gambaro</name><affiliation><nlm:affiliation>Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Via Moscati 31, Rome 00168, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Malerba, Giovanni" sort="Malerba, Giovanni" uniqKey="Malerba G" first="Giovanni" last="Malerba">Giovanni Malerba</name><affiliation><nlm:affiliation>Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, Verona 37134, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name><affiliation><nlm:affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Jacobs, Gunnar" sort="Jacobs, Gunnar" uniqKey="Jacobs G" first="Gunnar" last="Jacobs">Gunnar Jacobs</name><affiliation><nlm:affiliation>Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Niemannsweg 11, Kiel 24105, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Guo" sort="Li, Guo" uniqKey="Li G" first="Guo" last="Li">Guo Li</name><affiliation><nlm:affiliation>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, Washington 98101, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, Neuherberg 85764, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation><nlm:affiliation>Austrian Stroke Prevention Study, Institute of Molecular Biology and Biochemistry, Department of Neurology, Medical University Graz, Harrachgasse 21, Graz 8010, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name><affiliation><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation><nlm:affiliation>Institute for Community Medicine, University of Greifswald, Walther-Rathenau-Strasse 48, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kroemer, Heyo K" sort="Kroemer, Heyo K" uniqKey="Kroemer H" first="Heyo K" last="Kroemer">Heyo K. Kroemer</name><affiliation><nlm:affiliation>Institute of Pharmacology, University of Greifswald, Friedrich-Loeffler-Straße 23d, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kramer, Holly" sort="Kramer, Holly" uniqKey="Kramer H" first="Holly" last="Kramer">Holly Kramer</name><affiliation><nlm:affiliation>Department of Public Health Sciences, Loyola Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lin, Honghuang" sort="Lin, Honghuang" uniqKey="Lin H" first="Honghuang" last="Lin">Honghuang Lin</name><affiliation><nlm:affiliation>Boston University School of Medicine, 72 East Concord Street, B-616, Boston, Massachusetts 02118, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Leach, I Mateo" sort="Leach, I Mateo" uniqKey="Leach I" first="I Mateo" last="Leach">I Mateo Leach</name><affiliation><nlm:affiliation>Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name><affiliation><nlm:affiliation>Robertson Centre for Biostatistics, University of Glasgow, R1122B Level 11, Robertson Centre, Boyd Orr Building, Glasgow G12 8QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Guessous, Idris" sort="Guessous, Idris" uniqKey="Guessous I" first="Idris" last="Guessous">Idris Guessous</name><affiliation><nlm:affiliation>Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation><nlm:affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Borecki, Ingrid" sort="Borecki, Ingrid" uniqKey="Borecki I" first="Ingrid" last="Borecki">Ingrid Borecki</name><affiliation><nlm:affiliation>Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Box 8506, St Louis, Missouri 63108, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M" last="Heid">Iris M. Heid</name><affiliation><nlm:affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation><nlm:affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Persico, Ivana" sort="Persico, Ivana" uniqKey="Persico I" first="Ivana" last="Persico">Ivana Persico</name><affiliation><nlm:affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><affiliation><nlm:affiliation>Department of Cardiology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F" last="Felix">Janine F. Felix</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Divers, Jasmin" sort="Divers, Jasmin" uniqKey="Divers J" first="Jasmin" last="Divers">Jasmin Divers</name><affiliation><nlm:affiliation>Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University Health Sciences, 2326 Medical Center Boulevard, Winston-Salem, North Carolina 27157-1063, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lambert, Jean Charles" sort="Lambert, Jean Charles" uniqKey="Lambert J" first="Jean-Charles" last="Lambert">Jean-Charles Lambert</name><affiliation><nlm:affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</nlm:affiliation></affiliation></author><author><name sortKey="Stafford, Jeanette M" sort="Stafford, Jeanette M" uniqKey="Stafford J" first="Jeanette M" last="Stafford">Jeanette M. Stafford</name><affiliation><nlm:affiliation>Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University Health Sciences, 2326 Medical Center Boulevard, Winston-Salem, North Carolina 27157-1063, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gaspoz, Jean Michel" sort="Gaspoz, Jean Michel" uniqKey="Gaspoz J" first="Jean-Michel" last="Gaspoz">Jean-Michel Gaspoz</name><affiliation><nlm:affiliation>Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Smith, Jennifer A" sort="Smith, Jennifer A" uniqKey="Smith J" first="Jennifer A" last="Smith">Jennifer A. Smith</name><affiliation><nlm:affiliation>Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan 48109-2029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Faul, Jessica D" sort="Faul, Jessica D" uniqKey="Faul J" first="Jessica D" last="Faul">Jessica D. Faul</name><affiliation><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, 426 Thompson Street, #3456, Ann Arbor, Michigan 48104, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Jie Jin" sort="Wang, Jie Jin" uniqKey="Wang J" first="Jie Jin" last="Wang">Jie Jin Wang</name><affiliation><nlm:affiliation>Centre for Vision Research, Westmead Millennium Institute, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Ding, Jingzhong" sort="Ding, Jingzhong" uniqKey="Ding J" first="Jingzhong" last="Ding">Jingzhong Ding</name><affiliation><nlm:affiliation>Wake Forest School of Medicine, Department of Internal Medicine/Geriatrics, Medical center Boulevard, Winston-Salem, North Carolina 27157, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N" last="Hirschhorn">Joel N. Hirschhorn</name><affiliation><nlm:affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Attia, John" sort="Attia, John" uniqKey="Attia J" first="John" last="Attia">John Attia</name><affiliation><nlm:affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Whitfield, John B" sort="Whitfield, John B" uniqKey="Whitfield J" first="John B" last="Whitfield">John B. Whitfield</name><affiliation><nlm:affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Chalmers, John" sort="Chalmers, John" uniqKey="Chalmers J" first="John" last="Chalmers">John Chalmers</name><affiliation><nlm:affiliation>University of Sydney, The George Institute for Global Health, Level 10, King George V Building, 83-117 Missenden Road, Camperdown, New South Wales 2050, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Viikari, Jorma" sort="Viikari, Jorma" uniqKey="Viikari J" first="Jorma" last="Viikari">Jorma Viikari</name><affiliation><nlm:affiliation>Department of Medicine, University of Turku, Turku University Hospital, PO Box 52, Turku 20521, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Coresh, Josef" sort="Coresh, Josef" uniqKey="Coresh J" first="Josef" last="Coresh">Josef Coresh</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Denny, Joshua C" sort="Denny, Joshua C" uniqKey="Denny J" first="Joshua C" last="Denny">Joshua C. Denny</name><affiliation><nlm:affiliation>Vanderbilt University School of Medicine, 448 Eskind Biomedical Library, 2209 Garland Avenue, Nashville, Tennessee 37212, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Karjalainen, Juha" sort="Karjalainen, Juha" uniqKey="Karjalainen J" first="Juha" last="Karjalainen">Juha Karjalainen</name><affiliation><nlm:affiliation>Department of Genetics, University of Groningen, University Medical Centre Groningen, PO Box 72, Groningen 9700 AB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Fernandes, Jyotika K" sort="Fernandes, Jyotika K" uniqKey="Fernandes J" first="Jyotika K" last="Fernandes">Jyotika K. Fernandes</name><affiliation><nlm:affiliation>Division of Endocrinology, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Endlich, Karlhans" sort="Endlich, Karlhans" uniqKey="Endlich K" first="Karlhans" last="Endlich">Karlhans Endlich</name><affiliation><nlm:affiliation>Institute of Anatomy and Cell Biology, University of Greifswald, Friedrich-Loeffler-Straße 23c, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Butterbach, Katja" sort="Butterbach, Katja" uniqKey="Butterbach K" first="Katja" last="Butterbach">Katja Butterbach</name><affiliation><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Keene, Keith L" sort="Keene, Keith L" uniqKey="Keene K" first="Keith L" last="Keene">Keith L. Keene</name><affiliation><nlm:affiliation>Center for Health Disparities, Department of Biology, East Carolina University, 1001 East 10th Street, N209 Howell Science Complex Mailstop 551, Greenville, North Carolina 27858, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lohman, Kurt" sort="Lohman, Kurt" uniqKey="Lohman K" first="Kurt" last="Lohman">Kurt Lohman</name><affiliation><nlm:affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Portas, Laura" sort="Portas, Laura" uniqKey="Portas L" first="Laura" last="Portas">Laura Portas</name><affiliation><nlm:affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation><nlm:affiliation>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Gateway Building, 3C309, 7201 Winsconsin Avenue, Bethesda, Maryland 20892-9205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lyytik Inen, Leo Pekka" sort="Lyytik Inen, Leo Pekka" uniqKey="Lyytik Inen L" first="Leo-Pekka" last="Lyytik Inen">Leo-Pekka Lyytik Inen</name><affiliation><nlm:affiliation>Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere 33520, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loic" last="Yengo">Loic Yengo</name><affiliation><nlm:affiliation>CNRS UMR 8199, 1 Rue du Professeur Calmette, Lille 59000, France.</nlm:affiliation></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation><nlm:affiliation>Department of Genetics, University of Groningen, University Medical Centre Groningen, PO Box 72, Groningen 9700 AB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation><nlm:affiliation>Clinical Research Branch, National Institute on Aging, 251 Bayview Blvd, Baltimore, Maryland 21250, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name><affiliation><nlm:affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kedenko, Lyudmyla" sort="Kedenko, Lyudmyla" uniqKey="Kedenko L" first="Lyudmyla" last="Kedenko">Lyudmyla Kedenko</name><affiliation><nlm:affiliation>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Müllner Hauptstraße 48, Salzburg 5020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Rao, Madhumathi" sort="Rao, Madhumathi" uniqKey="Rao M" first="Madhumathi" last="Rao">Madhumathi Rao</name><affiliation><nlm:affiliation>Division of Nephrology/Tufts Evidence Practice Center, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Struchalin, Maksim" sort="Struchalin, Maksim" uniqKey="Struchalin M" first="Maksim" last="Struchalin">Maksim Struchalin</name><affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Dr Molewaterplein, Rotterdam 50-603015 GE, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Kleber, Marcus E" sort="Kleber, Marcus E" uniqKey="Kleber M" first="Marcus E" last="Kleber">Marcus E. Kleber</name><affiliation><nlm:affiliation>Medical Clinic V, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Cavalieri, Margherita" sort="Cavalieri, Margherita" uniqKey="Cavalieri M" first="Margherita" last="Cavalieri">Margherita Cavalieri</name><affiliation><nlm:affiliation>Austrian Stroke Prevention Study, Department of Neurology, Division of Special Neurology, Medical University Graz, Auenbruggerplatz 22, Graz 8036, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Haun, Margot" sort="Haun, Margot" uniqKey="Haun M" first="Margot" last="Haun">Margot Haun</name><affiliation><nlm:affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Cornelis, Marilyn C" sort="Cornelis, Marilyn C" uniqKey="Cornelis M" first="Marilyn C" last="Cornelis">Marilyn C. Cornelis</name><affiliation><nlm:affiliation>Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ciullo, Marina" sort="Ciullo, Marina" uniqKey="Ciullo M" first="Marina" last="Ciullo">Marina Ciullo</name><affiliation><nlm:affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pirastu, Mario" sort="Pirastu, Mario" uniqKey="Pirastu M" first="Mario" last="Pirastu">Mario Pirastu</name><affiliation><nlm:affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="De Andrade, Mariza" sort="De Andrade, Mariza" uniqKey="De Andrade M" first="Mariza" last="De Andrade">Mariza De Andrade</name><affiliation><nlm:affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mcevoy, Mark A" sort="Mcevoy, Mark A" uniqKey="Mcevoy M" first="Mark A" last="Mcevoy">Mark A. Mcevoy</name><affiliation><nlm:affiliation>Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, HRMC, New South Wales 2310, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Woodward, Mark" sort="Woodward, Mark" uniqKey="Woodward M" first="Mark" last="Woodward">Mark Woodward</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Adam, Martin" sort="Adam, Martin" uniqKey="Adam M" first="Martin" last="Adam">Martin Adam</name><affiliation><nlm:affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Cocca, Massimiliano" sort="Cocca, Massimiliano" uniqKey="Cocca M" first="Massimiliano" last="Cocca">Massimiliano Cocca</name><affiliation><nlm:affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Nauck, Matthias" sort="Nauck, Matthias" uniqKey="Nauck M" first="Matthias" last="Nauck">Matthias Nauck</name><affiliation><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Imboden, Medea" sort="Imboden, Medea" uniqKey="Imboden M" first="Medea" last="Imboden">Medea Imboden</name><affiliation><nlm:affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name><affiliation><nlm:affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Pruijm, Menno" sort="Pruijm, Menno" uniqKey="Pruijm M" first="Menno" last="Pruijm">Menno Pruijm</name><affiliation><nlm:affiliation>Service of Nephrology, Lausanne University Hospital, Rue du Bugnon 17, Lausanne 1005, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Metzger, Marie" sort="Metzger, Marie" uniqKey="Metzger M" first="Marie" last="Metzger">Marie Metzger</name><affiliation><nlm:affiliation>Inserm UMRS 1018, CESP Team 10, Université Paris-Sud, 16 avenue Paul Vaillant Couturier, Villejuif 94807, France.</nlm:affiliation></affiliation></author><author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><affiliation><nlm:affiliation>Department of Medicine, University of Leipzig, Liebigstraße 18, Leipzig 04103, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Evans, Michele K" sort="Evans, Michele K" uniqKey="Evans M" first="Michele K" last="Evans">Michele K. Evans</name><affiliation><nlm:affiliation>Health Disparities Research Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, NIH Biomedical Center, 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sale, Michele M" sort="Sale, Michele M" uniqKey="Sale M" first="Michele M" last="Sale">Michele M. Sale</name><affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Medicine (Cardiovascular Medicine), University of Virginia, PO Box 800717, Charlottesville, Virginia 22908, USA.</nlm:affiliation></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation><nlm:affiliation>Department of Clinical Physiology, Tampere University Hospital, University of Tampere, School of Medicine, Tampere 33521, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name><affiliation><nlm:affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Bochud, Murielle" sort="Bochud, Murielle" uniqKey="Bochud M" first="Murielle" last="Bochud">Murielle Bochud</name><affiliation><nlm:affiliation>University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Route de la Corniche 2, Epalinges CH-1066, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Rheinberger, Myriam" sort="Rheinberger, Myriam" uniqKey="Rheinberger M" first="Myriam" last="Rheinberger">Myriam Rheinberger</name><affiliation><nlm:affiliation>Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation><nlm:affiliation>Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Bouatia Naji, Nabila" sort="Bouatia Naji, Nabila" uniqKey="Bouatia Naji N" first="Nabila" last="Bouatia-Naji">Nabila Bouatia-Naji</name><affiliation><nlm:affiliation>INSERM UMR970, Paris Cardiovascular Research Center (PARCC), 56 rue Leblanc, Paris F-75015, France.</nlm:affiliation></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><affiliation><nlm:affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Hastie, Nick" sort="Hastie, Nick" uniqKey="Hastie N" first="Nick" last="Hastie">Nick Hastie</name><affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Probst Hensch, Nicole" sort="Probst Hensch, Nicole" uniqKey="Probst Hensch N" first="Nicole" last="Probst-Hensch">Nicole Probst-Hensch</name><affiliation><nlm:affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name><affiliation><nlm:affiliation>Wellcome Trust Sanger Institute, Hinxton CB10 1HH, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Devuyst, Olivier" sort="Devuyst, Olivier" uniqKey="Devuyst O" first="Olivier" last="Devuyst">Olivier Devuyst</name><affiliation><nlm:affiliation>University of Zurich, Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, Winterthurerstrasse 190, Zürich 8057, Switzerland.</nlm:affiliation></affiliation></author><author><name sortKey="Raitakari, Olli" sort="Raitakari, Olli" uniqKey="Raitakari O" first="Olli" last="Raitakari">Olli Raitakari</name><affiliation><nlm:affiliation>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku University Hospital, Department of Clinical Physiology, PO Box 52, Turku 20521, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Gottesman, Omri" sort="Gottesman, Omri" uniqKey="Gottesman O" first="Omri" last="Gottesman">Omri Gottesman</name><affiliation><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H" last="Franco">Oscar H. Franco</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name><affiliation><nlm:affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Gasparini, Paolo" sort="Gasparini, Paolo" uniqKey="Gasparini P" first="Paolo" last="Gasparini">Paolo Gasparini</name><affiliation><nlm:affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Munroe, Patricia B" sort="Munroe, Patricia B" uniqKey="Munroe P" first="Patricia B" last="Munroe">Patricia B. Munroe</name><affiliation><nlm:affiliation>Department Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><affiliation><nlm:affiliation>Harvard Medical School, 900 Commonwealth Avenue East, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mitchell, Paul" sort="Mitchell, Paul" uniqKey="Mitchell P" first="Paul" last="Mitchell">Paul Mitchell</name><affiliation><nlm:affiliation>Centre for Vision Research, Westmead Millennium Institute, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Muntner, Paul" sort="Muntner, Paul" uniqKey="Muntner P" first="Paul" last="Muntner">Paul Muntner</name><affiliation><nlm:affiliation>University of Alabama at Birmingham, Department of Medicine, 1530 3rd Avenue, South Birmingham, Alabama 35294-0022, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Meisinger, Christa" sort="Meisinger, Christa" uniqKey="Meisinger C" first="Christa" last="Meisinger">Christa Meisinger</name><affiliation><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Smit, Johannes H" sort="Smit, Johannes H" uniqKey="Smit J" first="Johannes H" last="Smit">Johannes H. Smit</name><affiliation><nlm:affiliation>Department of Psychiatry and EMGO+ Institute, VU University Medical Center, A.J. Ernststraat 1187, Amsterdam 1081 HL, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name><affiliation><nlm:affiliation>IFB AdiposityDiseases, University of Leipzig, Liebigstraße 21, Leipzig 04103, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wild, Philipp S" sort="Wild, Philipp S" uniqKey="Wild P" first="Philipp S" last="Wild">Philipp S. Wild</name><affiliation><nlm:affiliation>Medical University Center Mainz, Langenbeckstraße 1, Mainz 55131, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation><nlm:affiliation>CNRS UMR 8199, 1 Rue du Professeur Calmette, Lille 59000, France.</nlm:affiliation></affiliation></author><author><name sortKey="Rettig, Rainer" sort="Rettig, Rainer" uniqKey="Rettig R" first="Rainer" last="Rettig">Rainer Rettig</name><affiliation><nlm:affiliation>Institute of Physiology, University of Greifswald, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation><nlm:affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</nlm:affiliation></affiliation></author><author><name sortKey="Biffar, Reiner" sort="Biffar, Reiner" uniqKey="Biffar R" first="Reiner" last="Biffar">Reiner Biffar</name><affiliation><nlm:affiliation>Clinic for Prosthodontic Dentistry, Gerostomatology and Material Science, University of Greifswald, Rotgerberstraße 8, Greifswald 17475, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><affiliation><nlm:affiliation>Austrian Stroke Prevention Study, Department of Neurology, Division of Special Neurology, Medical University Graz, Auenbruggerplatz 22, Graz 8036, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Middelberg, Rita P S" sort="Middelberg, Rita P S" uniqKey="Middelberg R" first="Rita P S" last="Middelberg">Rita P S. Middelberg</name><affiliation><nlm:affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Carroll, Robert J" sort="Carroll, Robert J" uniqKey="Carroll R" first="Robert J" last="Carroll">Robert J. Carroll</name><affiliation><nlm:affiliation>Vanderbilt University School of Medicine, 448 Eskind Biomedical Library, 2209 Garland Avenue, Nashville, Tennessee 37212, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><affiliation><nlm:affiliation>Department of Psychiatry and EMGO+ Institute, VU University Medical Center, A.J. Ernststraat 1187, Amsterdam 1081 HL, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Scott, Rodney J" sort="Scott, Rodney J" uniqKey="Scott R" first="Rodney J" last="Scott">Rodney J. Scott</name><affiliation><nlm:affiliation>School of Biomedical Sciences and Pharmacy, University of Newcastle, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, HRMC, New South Wales 2310, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Katz, Ronit" sort="Katz, Ronit" uniqKey="Katz R" first="Ronit" last="Katz">Ronit Katz</name><affiliation><nlm:affiliation>Kidney Research Institute, University of Washington, Box 359606, 325 9th Avenue, Seattle, Washington 98104, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sedaghat, Sanaz" sort="Sedaghat, Sanaz" uniqKey="Sedaghat S" first="Sanaz" last="Sedaghat">Sanaz Sedaghat</name><affiliation><nlm:affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><affiliation><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L R" last="Kardia">Sharon L R. Kardia</name><affiliation><nlm:affiliation>Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan 48109-2029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ulivi, Sheila" sort="Ulivi, Sheila" uniqKey="Ulivi S" first="Sheila" last="Ulivi">Sheila Ulivi</name><affiliation><nlm:affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Via dell'Istria 65, Trieste 34137, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><affiliation><nlm:affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Enroth, Stefan" sort="Enroth, Stefan" uniqKey="Enroth S" first="Stefan" last="Enroth">Stefan Enroth</name><affiliation><nlm:affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Kloiber, Stefan" sort="Kloiber, Stefan" uniqKey="Kloiber S" first="Stefan" last="Kloiber">Stefan Kloiber</name><affiliation><nlm:affiliation>Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, Munich 80804, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><affiliation><nlm:affiliation>Department of Cardiology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Stengel, Benedicte" sort="Stengel, Benedicte" uniqKey="Stengel B" first="Benedicte" last="Stengel">Benedicte Stengel</name><affiliation><nlm:affiliation>Inserm UMRS 1018, CESP Team 10, Université Paris-Sud, 16 avenue Paul Vaillant Couturier, Villejuif 94807, France.</nlm:affiliation></affiliation></author><author><name sortKey="Hancock, Stephen J" sort="Hancock, Stephen J" uniqKey="Hancock S" first="Stephen J" last="Hancock">Stephen J. Hancock</name><affiliation><nlm:affiliation>Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Turner, Stephen T" sort="Turner, Stephen T" uniqKey="Turner S" first="Stephen T" last="Turner">Stephen T. Turner</name><affiliation><nlm:affiliation>Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Rosas, Sylvia E" sort="Rosas, Sylvia E" uniqKey="Rosas S" first="Sylvia E" last="Rosas">Sylvia E. Rosas</name><affiliation><nlm:affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Stracke, Sylvia" sort="Stracke, Sylvia" uniqKey="Stracke S" first="Sylvia" last="Stracke">Sylvia Stracke</name><affiliation><nlm:affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</nlm:affiliation></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation><nlm:affiliation>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Gateway Building, 3C309, 7201 Winsconsin Avenue, Bethesda, Maryland 20892-9205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Zeller, Tanja" sort="Zeller, Tanja" uniqKey="Zeller T" first="Tanja" last="Zeller">Tanja Zeller</name><affiliation><nlm:affiliation>University Heart Center Hamburg, Clinic for general and interventional cardiology, Martinistraße 52, Hamburg 20246, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name><affiliation><nlm:affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation><nlm:affiliation>Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere 33520, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><affiliation><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Nikopensius, Tiit" sort="Nikopensius, Tiit" uniqKey="Nikopensius T" first="Tiit" last="Nikopensius">Tiit Nikopensius</name><affiliation><nlm:affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</nlm:affiliation></affiliation></author><author><name sortKey="Esko, Tonu" sort="Esko, Tonu" uniqKey="Esko T" first="Tonu" last="Esko">Tonu Esko</name><affiliation><nlm:affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation><nlm:affiliation>Clinical Research Branch, National Institute on Aging, 251 Bayview Blvd, Baltimore, Maryland 21250, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gyllensten, Ulf" sort="Gyllensten, Ulf" uniqKey="Gyllensten U" first="Ulf" last="Gyllensten">Ulf Gyllensten</name><affiliation><nlm:affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name><affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Emilsson, Valur" sort="Emilsson, Valur" uniqKey="Emilsson V" first="Valur" last="Emilsson">Valur Emilsson</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Aalto, Ville" sort="Aalto, Ville" uniqKey="Aalto V" first="Ville" last="Aalto">Ville Aalto</name><affiliation><nlm:affiliation>Department of Clinical Physiology, Turku University Hospital, Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, PO Box 52, Turku 20521, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation><nlm:affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><affiliation><nlm:affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, Wei Min" sort="Chen, Wei Min" uniqKey="Chen W" first="Wei-Min" last="Chen">Wei-Min Chen</name><affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Medicine (Cardiovascular Medicine), University of Virginia, PO Box 800717, Charlottesville, Virginia 22908, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Igl, Wilmar" sort="Igl, Wilmar" uniqKey="Igl W" first="Wilmar" last="Igl">Wilmar Igl</name><affiliation><nlm:affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="M Rz, Winfried" sort="M Rz, Winfried" uniqKey="M Rz W" first="Winfried" last="M Rz">Winfried M Rz</name><affiliation><nlm:affiliation>Synlab Academy, Synlab Services GmbH, Oberer Eselsberg 45, Ulm 89081, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name><affiliation><nlm:affiliation>Department of Internal Medicine II-Cardiology, University of Ulm Medical Centre, Albert-Einstein-Allee 23, Ulm 89081, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Lieb, Wolfgang" sort="Lieb, Wolfgang" uniqKey="Lieb W" first="Wolfgang" last="Lieb">Wolfgang Lieb</name><affiliation><nlm:affiliation>Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Niemannsweg 11, Kiel 24105, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><affiliation><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation><nlm:affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation><nlm:affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Pramstaller, Peter P" sort="Pramstaller, Peter P" uniqKey="Pramstaller P" first="Peter P" last="Pramstaller">Peter P. Pramstaller</name><affiliation><nlm:affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Parsa, Afshin" sort="Parsa, Afshin" uniqKey="Parsa A" first="Afshin" last="Parsa">Afshin Parsa</name><affiliation><nlm:affiliation>University of Maryland Medical School, Division of Nephrology, 685 W. Baltimore Street, MSTF 314, Baltimore, Maryland 21201, USA.</nlm:affiliation></affiliation></author><author><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R" last="O'Connell">Jeffrey R. O'Connell</name><affiliation><nlm:affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Susztak, Katalin" sort="Susztak, Katalin" uniqKey="Susztak K" first="Katalin" last="Susztak">Katalin Susztak</name><affiliation><nlm:affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hamet, Pavel" sort="Hamet, Pavel" uniqKey="Hamet P" first="Pavel" last="Hamet">Pavel Hamet</name><affiliation><nlm:affiliation>CRCHUM, University of Montreal, CHUM Research Center, Technopôle Angus, 900 Saint-Denis, Montreal, Québec, Canada H2X 0A9.</nlm:affiliation></affiliation></author><author><name sortKey="Tremblay, Johanne" sort="Tremblay, Johanne" uniqKey="Tremblay J" first="Johanne" last="Tremblay">Johanne Tremblay</name><affiliation><nlm:affiliation>CRCHUM, University of Montreal, CHUM Research Center, Technopôle Angus, 900 Saint-Denis, Montreal, Québec, Canada H2X 0A9.</nlm:affiliation></affiliation></author><author><name sortKey="De Boer, Ian H" sort="De Boer, Ian H" uniqKey="De Boer I" first="Ian H" last="De Boer">Ian H. De Boer</name><affiliation><nlm:affiliation>Kidney Research Institute, University of Washington, Box 359606, 325 9th Avenue, Seattle, Washington 98104, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Boger, Carsten A" sort="Boger, Carsten A" uniqKey="Boger C" first="Carsten A" last="Böger">Carsten A. Böger</name><affiliation><nlm:affiliation>Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Goessling, Wolfram" sort="Goessling, Wolfram" uniqKey="Goessling W" first="Wolfram" last="Goessling">Wolfram Goessling</name><affiliation><nlm:affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, New Research Building77 Avenue Louis Pasteur, Room 458, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><affiliation><nlm:affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kottgen, Anna" sort="Kottgen, Anna" uniqKey="Kottgen A" first="Anna" last="Köttgen">Anna Köttgen</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kao, W H Linda" sort="Kao, W H Linda" uniqKey="Kao W" first="W H Linda" last="Kao">W H Linda Kao</name><affiliation><nlm:affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S" last="Fox">Caroline S. Fox</name><affiliation><nlm:affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Nature communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Gene Expression Regulation</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Genotype</term><term>Humans</term><term>Renal Insufficiency, Chronic (genetics)</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Renal Insufficiency, Chronic</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Gene Expression Regulation</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Genotype</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. We identify 24 new and confirm 29 previously identified loci. Of these 53 loci, 19 associate with eGFR among individuals with diabetes. Using bioinformatics, we show that identified genes at eGFR loci are enriched for expression in kidney tissues and in pathways relevant for kidney development and transmembrane transporter activity, kidney structure, and regulation of glucose metabolism. Chromatin state mapping and DNase I hypersensitivity analyses across adult tissues demonstrate preferential mapping of associated variants to regulatory regions in kidney but not extra-renal tissues. These findings suggest that genetic determinants of eGFR are mediated largely through direct effects within the kidney and highlight important cell types and biological pathways.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26831199</PMID><DateCreated><Year>2016</Year><Month>02</Month><Day>02</Day></DateCreated><DateCompleted><Year>2016</Year><Month>06</Month><Day>17</Day></DateCompleted><DateRevised><Year>2017</Year><Month>11</Month><Day>10</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2041-1723</ISSN><JournalIssue CitedMedium="Internet"><Volume>7</Volume><PubDate><Year>2016</Year><Month>Jan</Month><Day>21</Day></PubDate></JournalIssue><Title>Nature communications</Title><ISOAbbreviation>Nat Commun</ISOAbbreviation></Journal><ArticleTitle>Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.</ArticleTitle><Pagination><MedlinePgn>10023</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/ncomms10023</ELocationID><Abstract><AbstractText>Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. We identify 24 new and confirm 29 previously identified loci. Of these 53 loci, 19 associate with eGFR among individuals with diabetes. Using bioinformatics, we show that identified genes at eGFR loci are enriched for expression in kidney tissues and in pathways relevant for kidney development and transmembrane transporter activity, kidney structure, and regulation of glucose metabolism. Chromatin state mapping and DNase I hypersensitivity analyses across adult tissues demonstrate preferential mapping of associated variants to regulatory regions in kidney but not extra-renal tissues. These findings suggest that genetic determinants of eGFR are mediated largely through direct effects within the kidney and highlight important cell types and biological pathways.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Pattaro</LastName><ForeName>Cristian</ForeName><Initials>C</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-8309-094X</Identifier><AffiliationInfo><Affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Teumer</LastName><ForeName>Alexander</ForeName><Initials>A</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-8309-094X</Identifier><AffiliationInfo><Affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute for Community Medicine, University of Greifswald, Walther-Rathenau-Strasse 48, Greifswald 17487, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gorski</LastName><ForeName>Mathias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chu</LastName><ForeName>Audrey Y</ForeName><Initials>AY</Initials><AffiliationInfo><Affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Man</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mijatovic</LastName><ForeName>Vladan</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, Verona 37134, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Garnaas</LastName><ForeName>Maija</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, New Research Building77 Avenue Louis Pasteur, Room 458, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tin</LastName><ForeName>Adrienne</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sorice</LastName><ForeName>Rossella</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Yong</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine IV, University Hospital Freiburg, Berliner Allee 29, Freiburg 79110, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Taliun</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olden</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Foster</LastName><ForeName>Meredith</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Nephrology/Tufts Evidence Practice Center, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Qiong</ForeName><Initials>Q</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-3658-1375</Identifier><AffiliationInfo><Affiliation>Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, Massachusetts 02118, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Ming-Huei</ForeName><Initials>MH</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, Massachusetts 02118, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Neurology, Boston University School of Medicine, 72 East Concord ST B603, Boston, Massachusetts 02118, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pers</LastName><ForeName>Tune H</ForeName><Initials>TH</Initials><AffiliationInfo><Affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 2142, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johnson</LastName><ForeName>Andrew D</ForeName><Initials>AD</Initials><AffiliationInfo><Affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ko</LastName><ForeName>Yi-An</ForeName><Initials>YA</Initials><AffiliationInfo><Affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fuchsberger</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tayo</LastName><ForeName>Bamidele</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Public Health Sciences, Loyola Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nalls</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Laboratory of Neurogenetics, Building 35-Porter Building, 1A1015, National Institute on Aging/NIH, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Feitosa</LastName><ForeName>Mary F</ForeName><Initials>MF</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Box 8506, St Louis, Missouri 63108, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Isaacs</LastName><ForeName>Aaron</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Medical Systems Biology Leiden, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dehghan</LastName><ForeName>Abbas</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>d'Adamo</LastName><ForeName>Pio</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adeyemo</LastName><ForeName>Adebowale</ForeName><Initials>A</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-3105-3231</Identifier><AffiliationInfo><Affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dieffenbach</LastName><ForeName>Aida Karina</ForeName><Initials>AK</Initials><AffiliationInfo><Affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Cancer Consortium (DKTK), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zonderman</LastName><ForeName>Alan B</ForeName><Initials>AB</Initials><AffiliationInfo><Affiliation>Laboratory of Personality and Cognition, National Institute on Aging, National Institutes of Health, NIH Biomedical Center, 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nolte</LastName><ForeName>Ilja M</ForeName><Initials>IM</Initials><AffiliationInfo><Affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Most</LastName><ForeName>Peter J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wright</LastName><ForeName>Alan F</ForeName><Initials>AF</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shuldiner</LastName><ForeName>Alan R</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, 10 North Greene Street, Baltimore, Maryland 21201, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Morrison</LastName><ForeName>Alanna C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, 1200 Pressler St Suite 453E, Houston, Texas 77030, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hofman</LastName><ForeName>Albert</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>Albert V</ForeName><Initials>AV</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-1942-5845</Identifier><AffiliationInfo><Affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Iceland, Sæmundargötu 2, Reykjavik 101, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dreisbach</LastName><ForeName>Albert W</ForeName><Initials>AW</Initials><AffiliationInfo><Affiliation>Division of Nephrology, University of Mississippi, 2500 North State Street, Jackson, Mississippi 39216, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Franke</LastName><ForeName>Andre</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Clinical Molecular Biology, Christian-Albrechts University of Kiel, Schittenhelmstraße 12, Kiel 24105, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Uitterlinden</LastName><ForeName>Andre G</ForeName><Initials>AG</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus University Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Metspalu</LastName><ForeName>Andres</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Molecular and Cell Biology, University of Tartu and Estonian Biocenter, Riia 23, Tartu 51010, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tonjes</LastName><ForeName>Anke</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Leipzig, Liebigstraße 18, Leipzig 04103, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lupo</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Nephrology, Department of Medicine, University of Verona, Piazzale Aristide Stefani 1, Verona 37126, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Robino</LastName><ForeName>Antonietta</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johansson</LastName><ForeName>Åsa</ForeName><Initials>Å</Initials><AffiliationInfo><Affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Demirkan</LastName><ForeName>Ayse</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kollerits</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Freedman</LastName><ForeName>Barry I</ForeName><Initials>BI</Initials><AffiliationInfo><Affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ponte</LastName><ForeName>Belen</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospital, 4 rue Gabrielle-Perret-Gentil, Geneve 1211, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oostra</LastName><ForeName>Ben A</ForeName><Initials>BA</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Paulweber</LastName><ForeName>Bernhard</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Müllner Hauptstraße 48, Salzburg 5020, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Krämer</LastName><ForeName>Bernhard K</ForeName><Initials>BK</Initials><AffiliationInfo><Affiliation>University Medical Centre Mannheim, 5th Department of Medicine, University of Heidelberg, Theodor Kutzer Ufer 1-3, Mannheim 68167, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mitchell</LastName><ForeName>Braxton D</ForeName><Initials>BD</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, 10 North Greene Street, Baltimore, Maryland 21201, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buckley</LastName><ForeName>Brendan M</ForeName><Initials>BM</Initials><AffiliationInfo><Affiliation>Department of Pharmacology and Therapeutics, University College Cork, Clinical Investigations Building, Western Rd, Cork, Ireland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peralta</LastName><ForeName>Carmen A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Division of Nephrology, University of California, San Francisco Medical School and San Francisco VA Medical Center, 4150 Clement Street, San Francisco, California 94121, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hayward</LastName><ForeName>Caroline</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Helmer</LastName><ForeName>Catherine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>INSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux F-33000, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux F-33000, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rotimi</LastName><ForeName>Charles N</ForeName><Initials>CN</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-5759-053X</Identifier><AffiliationInfo><Affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shaffer</LastName><ForeName>Christian M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Vanderbilt University School of Medicine, 2215-B Garland Avenue 1224-MRB4 (Light Hall)Nashville, Tennessee 37232, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Müller</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>University Heart Center Hamburg, Clinic for general and interventional cardiology, Martinistraße 52, Hamburg 20246, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, Martinistraße 52, Hamburg 20246, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sala</LastName><ForeName>Cinzia</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Duijn</LastName><ForeName>Cornelia M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Dr Molewaterplein 50, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saint-Pierre</LastName><ForeName>Aude</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM U1078, Etablissement Français du Sang, 46 rue Félix Le Dantec, CS 51819, Brest Cedex 2 29218, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ackermann</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospital, 4 rue Gabrielle-Perret-Gentil, Geneve 1211, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shriner</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr, MSC 5635, Bethesda, Maryland 20892-5635, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ruggiero</LastName><ForeName>Daniela</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Toniolo</LastName><ForeName>Daniela</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Molecular Genetics-CNR, Via Abbiategrasso 207, Pavia 27100, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Yingchang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cusi</LastName><ForeName>Daniele</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Health Sciences, University of Milano, Via Antonio di Rudinì 8, Milano 20142, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Czamara</LastName><ForeName>Darina</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, Munich 80804, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ellinghaus</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Institute of Clinical Molecular Biology, Christian-Albrechts University of Kiel, Schittenhelmstraße 12, Kiel 24105, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Siscovick</LastName><ForeName>David S</ForeName><Initials>DS</Initials><AffiliationInfo><Affiliation>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, Washington 98101, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ruderfer</LastName><ForeName>Douglas</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gieger</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grallert</LastName><ForeName>Harald</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Center for Diabetes Research (DZD), Ingolstaedter Landstraße 1, Neuherberg 85764, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rochtchina</LastName><ForeName>Elena</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Westmead Millennium Institute, Centre for Vision Research, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Atkinson</LastName><ForeName>Elizabeth J</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Holliday</LastName><ForeName>Elizabeth G</ForeName><Initials>EG</Initials><AffiliationInfo><Affiliation>Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Clinical Research Design, Information Technology and Statistical Support, Hunter Medical Research Institute, Newcastle, 1 Kookaburra Circuit, New Lambton Heights, New South Wales 2305, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boerwinkle</LastName><ForeName>Eric</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, 1200 Pressler St Suite 453E, Houston, Texas 77030, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Salvi</LastName><ForeName>Erika</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Health Sciences, University of Milano, Via Antonio di Rudinì 8, Milano 20142, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bottinger</LastName><ForeName>Erwin P</ForeName><Initials>EP</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Murgia</LastName><ForeName>Federico</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rivadeneira</LastName><ForeName>Fernando</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus University Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ernst</LastName><ForeName>Florian</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kronenberg</LastName><ForeName>Florian</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hu</LastName><ForeName>Frank B</ForeName><Initials>FB</Initials><AffiliationInfo><Affiliation>Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Navis</LastName><ForeName>Gerjan J</ForeName><Initials>GJ</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Curhan</LastName><ForeName>Gary C</ForeName><Initials>GC</Initials><AffiliationInfo><Affiliation>Brigham and Women's Hospital and Channing Laboratory, Harvard Medical School, 181 Longwood Avenue, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ehret</LastName><ForeName>George B</ForeName><Initials>GB</Initials><AffiliationInfo><Affiliation>Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, Geneva 1205, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Homuth</LastName><ForeName>Georg</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Coassin</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thun</LastName><ForeName>Gian-Andri</ForeName><Initials>GA</Initials><AffiliationInfo><Affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Basel, Petersplatz 1, Basel 4003, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pistis</LastName><ForeName>Giorgio</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gambaro</LastName><ForeName>Giovanni</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Via Moscati 31, Rome 00168, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Malerba</LastName><ForeName>Giovanni</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, Verona 37134, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Montgomery</LastName><ForeName>Grant W</ForeName><Initials>GW</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eiriksdottir</LastName><ForeName>Gudny</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacobs</LastName><ForeName>Gunnar</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Niemannsweg 11, Kiel 24105, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Guo</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, Washington 98101, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wichmann</LastName><ForeName>H-Erich</ForeName><Initials>HE</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstraße 1, Neuherberg 85764, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Klinikum Grosshadern, Ingolstädter Landstraße 1, Neuherberg 85764, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Campbell</LastName><ForeName>Harry</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Helena</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Austrian Stroke Prevention Study, Institute of Molecular Biology and Biochemistry, Department of Neurology, Medical University Graz, Harrachgasse 21, Graz 8010, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wallaschofski</LastName><ForeName>Henri</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Center for Cardiovascular Research (DZHK), Partner site Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Völzke</LastName><ForeName>Henry</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute for Community Medicine, University of Greifswald, Walther-Rathenau-Strasse 48, Greifswald 17487, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Center for Cardiovascular Research (DZHK), Partner site Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brenner</LastName><ForeName>Hermann</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Cancer Consortium (DKTK), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kroemer</LastName><ForeName>Heyo K</ForeName><Initials>HK</Initials><AffiliationInfo><Affiliation>Institute of Pharmacology, University of Greifswald, Friedrich-Loeffler-Straße 23d, Greifswald 17487, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kramer</LastName><ForeName>Holly</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Public Health Sciences, Loyola Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lin</LastName><ForeName>Honghuang</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Boston University School of Medicine, 72 East Concord Street, B-616, Boston, Massachusetts 02118, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leach</LastName><ForeName>I Mateo</ForeName><Initials>IM</Initials><AffiliationInfo><Affiliation>Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ford</LastName><ForeName>Ian</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Robertson Centre for Biostatistics, University of Glasgow, R1122B Level 11, Robertson Centre, Boyd Orr Building, Glasgow G12 8QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guessous</LastName><ForeName>Idris</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Community Prevention Unit, University Institute of Social and Preventive Medicine, Lausanne University Hospital, Route de la Corniche 10, Lausanne 1010, Switzerland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, Georgia 30322, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudan</LastName><ForeName>Igor</ForeName><Initials>I</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-6993-6884</Identifier><AffiliationInfo><Affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prokopenko</LastName><ForeName>Inga</ForeName><Initials>I</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-1624-7457</Identifier><AffiliationInfo><Affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borecki</LastName><ForeName>Ingrid</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Washington University School of Medicine, 4444 Forest Park Boulevard, Box 8506, St Louis, Missouri 63108, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heid</LastName><ForeName>Iris M</ForeName><Initials>IM</Initials><AffiliationInfo><Affiliation>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kolcic</LastName><ForeName>Ivana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Persico</LastName><ForeName>Ivana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jukema</LastName><ForeName>J Wouter</ForeName><Initials>JW</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Interuniversity Cardiology Institute of the Netherlands (ICIN), Moreelsepark 1, Utrecht 3511 EP, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Einthoven Laboratory for Experimental Vascular Medicine, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Durrer Center for Cardiogenetic Research, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wilson</LastName><ForeName>James F</ForeName><Initials>JF</Initials><AffiliationInfo><Affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Felix</LastName><ForeName>Janine F</ForeName><Initials>JF</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Divers</LastName><ForeName>Jasmin</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University Health Sciences, 2326 Medical Center Boulevard, Winston-Salem, North Carolina 27157-1063, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lambert</LastName><ForeName>Jean-Charles</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stafford</LastName><ForeName>Jeanette M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest University Health Sciences, 2326 Medical Center Boulevard, Winston-Salem, North Carolina 27157-1063, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gaspoz</LastName><ForeName>Jean-Michel</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>Jennifer A</ForeName><Initials>JA</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-3575-5468</Identifier><AffiliationInfo><Affiliation>Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan 48109-2029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Faul</LastName><ForeName>Jessica D</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>Survey Research Center, Institute for Social Research, University of Michigan, 426 Thompson Street, #3456, Ann Arbor, Michigan 48104, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Jie Jin</ForeName><Initials>JJ</Initials><AffiliationInfo><Affiliation>Centre for Vision Research, Westmead Millennium Institute, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ding</LastName><ForeName>Jingzhong</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Wake Forest School of Medicine, Department of Internal Medicine/Geriatrics, Medical center Boulevard, Winston-Salem, North Carolina 27157, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hirschhorn</LastName><ForeName>Joel N</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 2142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, NRB 0330, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Attia</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Whitfield</LastName><ForeName>John B</ForeName><Initials>JB</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chalmers</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>University of Sydney, The George Institute for Global Health, Level 10, King George V Building, 83-117 Missenden Road, Camperdown, New South Wales 2050, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Viikari</LastName><ForeName>Jorma</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Turku, Turku University Hospital, PO Box 52, Turku 20521, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Coresh</LastName><ForeName>Josef</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Welch Center for Prevention, Epidemiology and Clinical Research, 2024 East Monument St, Suite 2-600, Baltimore, Maryland 21287, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Denny</LastName><ForeName>Joshua C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Vanderbilt University School of Medicine, 448 Eskind Biomedical Library, 2209 Garland Avenue, Nashville, Tennessee 37212, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karjalainen</LastName><ForeName>Juha</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Genetics, University of Groningen, University Medical Centre Groningen, PO Box 72, Groningen 9700 AB, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fernandes</LastName><ForeName>Jyotika K</ForeName><Initials>JK</Initials><AffiliationInfo><Affiliation>Division of Endocrinology, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Endlich</LastName><ForeName>Karlhans</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Institute of Anatomy and Cell Biology, University of Greifswald, Friedrich-Loeffler-Straße 23c, Greifswald 17487, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Butterbach</LastName><ForeName>Katja</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, Heidelberg 69120, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keene</LastName><ForeName>Keith L</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Center for Health Disparities, Department of Biology, East Carolina University, 1001 East 10th Street, N209 Howell Science Complex Mailstop 551, Greenville, North Carolina 27858, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lohman</LastName><ForeName>Kurt</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Portas</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Launer</LastName><ForeName>Lenore J</ForeName><Initials>LJ</Initials><AffiliationInfo><Affiliation>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Gateway Building, 3C309, 7201 Winsconsin Avenue, Bethesda, Maryland 20892-9205, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lyytikäinen</LastName><ForeName>Leo-Pekka</ForeName><Initials>LP</Initials><AffiliationInfo><Affiliation>Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere 33520, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yengo</LastName><ForeName>Loic</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, 1 Rue du Professeur Calmette, Lille 59000, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Lille Pasteur Institute, 1 Rue du Professeur Calmette, Lille 59000, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Lille II University, 42 Rue paul Duez, Lille 59000, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Franke</LastName><ForeName>Lude</ForeName><Initials>L</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-5159-8802</Identifier><AffiliationInfo><Affiliation>Department of Genetics, University of Groningen, University Medical Centre Groningen, PO Box 72, Groningen 9700 AB, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferrucci</LastName><ForeName>Luigi</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Clinical Research Branch, National Institute on Aging, 251 Bayview Blvd, Baltimore, Maryland 21250, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rose</LastName><ForeName>Lynda M</ForeName><Initials>LM</Initials><AffiliationInfo><Affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kedenko</LastName><ForeName>Lyudmyla</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Müllner Hauptstraße 48, Salzburg 5020, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rao</LastName><ForeName>Madhumathi</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Nephrology/Tufts Evidence Practice Center, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Struchalin</LastName><ForeName>Maksim</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Dr Molewaterplein, Rotterdam 50-603015 GE, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Forensic Molecular Biology, Erasmus University Medical Center, Dr Molewaterplein, Rotterdam 50-603015 GE, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kleber</LastName><ForeName>Marcus E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>Medical Clinic V, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cavalieri</LastName><ForeName>Margherita</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Austrian Stroke Prevention Study, Department of Neurology, Division of Special Neurology, Medical University Graz, Auenbruggerplatz 22, Graz 8036, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haun</LastName><ForeName>Margot</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Innsbruck Medical University, Division of Genetic Epidemiology, Schoepfstraße 41, Innsbruck 6020, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cornelis</LastName><ForeName>Marilyn C</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ciullo</LastName><ForeName>Marina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR, Via P. Castellino 111, Napoli 80131, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pirastu</LastName><ForeName>Mario</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Population Genetics-CNR, Traversa La Crucca 3, 07040 Reg. Baldinca, Li Punti, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Andrade</LastName><ForeName>Mariza</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Biomedical Statistics and Informatics, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McEvoy</LastName><ForeName>Mark A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, HRMC, New South Wales 2310, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Woodward</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Sydney, The George Institute for Global Health, Level 10, King George V Building, 83-117 Missenden Road, Camperdown, New South Wales 2050, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine, University of Turku, Turku University Hospital, PO Box 52, Turku 20521, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The George Institute for Global Health, Nuffield Department of Population Health, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford OX3 7LF, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adam</LastName><ForeName>Martin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Basel, Petersplatz 1, Basel 4003, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cocca</LastName><ForeName>Massimiliano</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, Milano 20132, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nauck</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Center for Cardiovascular Research (DZHK), Partner site Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Imboden</LastName><ForeName>Medea</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Basel, Petersplatz 1, Basel 4003, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Waldenberger</LastName><ForeName>Melanie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstraße 1, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pruijm</LastName><ForeName>Menno</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Service of Nephrology, Lausanne University Hospital, Rue du Bugnon 17, Lausanne 1005, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Metzger</LastName><ForeName>Marie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Inserm UMRS 1018, CESP Team 10, Université Paris-Sud, 16 avenue Paul Vaillant Couturier, Villejuif 94807, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stumvoll</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Leipzig, Liebigstraße 18, Leipzig 04103, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>Michele K</ForeName><Initials>MK</Initials><AffiliationInfo><Affiliation>Health Disparities Research Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, NIH Biomedical Center, 251 Bayview Boulevard, Suite 100, Baltimore, Maryland 21224, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sale</LastName><ForeName>Michele M</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>Center for Public Health Genomics, Department of Medicine (Cardiovascular Medicine), University of Virginia, PO Box 800717, Charlottesville, Virginia 22908, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kähönen</LastName><ForeName>Mika</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Clinical Physiology, Tampere University Hospital, University of Tampere, School of Medicine, Tampere 33521, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boban</LastName><ForeName>Mladen</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bochud</LastName><ForeName>Murielle</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Route de la Corniche 2, Epalinges CH-1066, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rheinberger</LastName><ForeName>Myriam</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Verweij</LastName><ForeName>Niek</ForeName><Initials>N</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-4303-7685</Identifier><AffiliationInfo><Affiliation>Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen 9700 RB, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bouatia-Naji</LastName><ForeName>Nabila</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>INSERM UMR970, Paris Cardiovascular Research Center (PARCC), 56 rue Leblanc, Paris F-75015, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Paris Descartes University, Faculty of medicine, Paris Cité Sorbonne, 12 Rue de l'école de Médecine, Paris F-75006, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martin</LastName><ForeName>Nicholas G</ForeName><Initials>NG</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hastie</LastName><ForeName>Nick</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Probst-Hensch</LastName><ForeName>Nicole</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Swiss Tropical and Public Health Institute, PO Box 4002, Basel, Switzerland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Basel, Petersplatz 1, Basel 4003, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soranzo</LastName><ForeName>Nicole</ForeName><Initials>N</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-1095-3852</Identifier><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Hinxton CB10 1HH, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Devuyst</LastName><ForeName>Olivier</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>University of Zurich, Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, Winterthurerstrasse 190, Zürich 8057, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raitakari</LastName><ForeName>Olli</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku University Hospital, Department of Clinical Physiology, PO Box 52, Turku 20521, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gottesman</LastName><ForeName>Omri</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Franco</LastName><ForeName>Oscar H</ForeName><Initials>OH</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Polasek</LastName><ForeName>Ozren</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gasparini</LastName><ForeName>Paolo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" and University of Trieste, via dell'Istria 65/1, Trieste 34137, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Munroe</LastName><ForeName>Patricia B</ForeName><Initials>PB</Initials><AffiliationInfo><Affiliation>Department Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ridker</LastName><ForeName>Paul M</ForeName><Initials>PM</Initials><AffiliationInfo><Affiliation>Harvard Medical School, 900 Commonwealth Avenue East, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mitchell</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Centre for Vision Research, Westmead Millennium Institute, University of Sydney, C24 Westmead Hospital, New South Wales 2145, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Muntner</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>University of Alabama at Birmingham, Department of Medicine, 1530 3rd Avenue, South Birmingham, Alabama 35294-0022, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Alabama at Birmingham, Department of Epidemiology, 1530 3rd Avenue, South Birmingham, Alabama 35294-0022, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meisinger</LastName><ForeName>Christa</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smit</LastName><ForeName>Johannes H</ForeName><Initials>JH</Initials><AffiliationInfo><Affiliation>Department of Psychiatry and EMGO+ Institute, VU University Medical Center, A.J. Ernststraat 1187, Amsterdam 1081 HL, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>ICBP Consortium</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>AGEN Consortium</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>CARDIOGRAM</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>CHARGe-Heart Failure Group</CollectiveName></Author><Author ValidYN="Y"><CollectiveName>ECHOGen Consortium</CollectiveName></Author><Author ValidYN="Y"><LastName>Kovacs</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>IFB AdiposityDiseases, University of Leipzig, Liebigstraße 21, Leipzig 04103, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wild</LastName><ForeName>Philipp S</ForeName><Initials>PS</Initials><AffiliationInfo><Affiliation>Medical University Center Mainz, Langenbeckstraße 1, Mainz 55131, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Froguel</LastName><ForeName>Philippe</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, 1 Rue du Professeur Calmette, Lille 59000, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Lille Pasteur Institute, 1 Rue du Professeur Calmette, Lille 59000, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Lille II University, 42 Rue paul Duez, Lille 59000, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rettig</LastName><ForeName>Rainer</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute of Physiology, University of Greifswald, Greifswald 17487, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mägi</LastName><ForeName>Reedik</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Biffar</LastName><ForeName>Reiner</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Clinic for Prosthodontic Dentistry, Gerostomatology and Material Science, University of Greifswald, Rotgerberstraße 8, Greifswald 17475, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Reinhold</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Austrian Stroke Prevention Study, Department of Neurology, Division of Special Neurology, Medical University Graz, Auenbruggerplatz 22, Graz 8036, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Middelberg</LastName><ForeName>Rita P S</ForeName><Initials>RP</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology, Queensland Institute of Medical Research, QIMR, PO Royal Brisbane Hospital, Queensland 4029, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Carroll</LastName><ForeName>Robert J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>Vanderbilt University School of Medicine, 448 Eskind Biomedical Library, 2209 Garland Avenue, Nashville, Tennessee 37212, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Penninx</LastName><ForeName>Brenda W</ForeName><Initials>BW</Initials><AffiliationInfo><Affiliation>Department of Psychiatry and EMGO+ Institute, VU University Medical Center, A.J. Ernststraat 1187, Amsterdam 1081 HL, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scott</LastName><ForeName>Rodney J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>School of Biomedical Sciences and Pharmacy, University of Newcastle, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, HRMC, New South Wales 2310, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Katz</LastName><ForeName>Ronit</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Kidney Research Institute, University of Washington, Box 359606, 325 9th Avenue, Seattle, Washington 98104, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sedaghat</LastName><ForeName>Sanaz</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wild</LastName><ForeName>Sarah H</ForeName><Initials>SH</Initials><AffiliationInfo><Affiliation>Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG Scotland, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kardia</LastName><ForeName>Sharon L R</ForeName><Initials>SL</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, Michigan 48109-2029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ulivi</LastName><ForeName>Sheila</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Via dell'Istria 65, Trieste 34137, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hwang</LastName><ForeName>Shih-Jen</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Enroth</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-5056-9137</Identifier><AffiliationInfo><Affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kloiber</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Max Planck Institute of Psychiatry, Kraepelinstraße 2-10, Munich 80804, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Trompet</LastName><ForeName>Stella</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stengel</LastName><ForeName>Benedicte</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Inserm UMRS 1018, CESP Team 10, Université Paris-Sud, 16 avenue Paul Vaillant Couturier, Villejuif 94807, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hancock</LastName><ForeName>Stephen J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, HMRI Building1, Kookaburra Circuit, New Lambton New South Wales 2305, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Clinical Research Design, Information Technology and Statistical Support, Hunter Medical Research Institute, Newcastle, 1 Kookaburra Circuit, New Lambton Heights, New South Wales 2305, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Turner</LastName><ForeName>Stephen T</ForeName><Initials>ST</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rosas</LastName><ForeName>Sylvia E</ForeName><Initials>SE</Initials><AffiliationInfo><Affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stracke</LastName><ForeName>Sylvia</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Clinic for Internal Medicine A, University of Greifswald, Friedrich-Loeffler-Straße 23a, Greifswald 17475, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harris</LastName><ForeName>Tamara B</ForeName><Initials>TB</Initials><AffiliationInfo><Affiliation>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Gateway Building, 3C309, 7201 Winsconsin Avenue, Bethesda, Maryland 20892-9205, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zeller</LastName><ForeName>Tanja</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>University Heart Center Hamburg, Clinic for general and interventional cardiology, Martinistraße 52, Hamburg 20246, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, Martinistraße 52, Hamburg 20246, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zemunik</LastName><ForeName>Tatijana</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Croatian Centre for Global Health, University of Split Medical School, Šoltanska 2, Split 21000, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lehtimäki</LastName><ForeName>Terho</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere 33520, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Illig</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aspelund</LastName><ForeName>Thor</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Iceland, Sæmundargötu 2, Reykjavik 101, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nikopensius</LastName><ForeName>Tiit</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Molecular and Cell Biology, University of Tartu and Estonian Biocenter, Riia 23, Tartu 51010, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Esko</LastName><ForeName>Tonu</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Estonian Genome Center of University of Tartu (EGCUT), Riia 23B, Tartu 51010, Estonia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Molecular and Cell Biology, University of Tartu and Estonian Biocenter, Riia 23, Tartu 51010, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tanaka</LastName><ForeName>Toshiko</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Clinical Research Branch, National Institute on Aging, 251 Bayview Blvd, Baltimore, Maryland 21250, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gyllensten</LastName><ForeName>Ulf</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Völker</LastName><ForeName>Uwe</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Loeffler-Straße 15a, Greifswald 17487, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Center for Cardiovascular Research (DZHK), Partner site Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald 17475, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Emilsson</LastName><ForeName>Valur</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Pharmaceutical Sciences, University of Iceland, Sæmundargata 2, Reykjavik 101, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vitart</LastName><ForeName>Veronique</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aalto</LastName><ForeName>Ville</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Clinical Physiology, Turku University Hospital, Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, PO Box 52, Turku 20521, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gudnason</LastName><ForeName>Vilmundur</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Research Institute, Holtasmari 1, Kopavogur 201, Iceland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Iceland, Sæmundargötu 2, Reykjavik 101, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chouraki</LastName><ForeName>Vincent</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>INSERM U744, Institut Pasteur de Lille, 1 rue du Pr, Calmette, Lille Cédex 59019, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Wei-Min</ForeName><Initials>WM</Initials><AffiliationInfo><Affiliation>Center for Public Health Genomics, Department of Medicine (Cardiovascular Medicine), University of Virginia, PO Box 800717, Charlottesville, Virginia 22908, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Igl</LastName><ForeName>Wilmar</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Uppsala University, Department of Immunology, Genetics and Pathology, Biomedical Center, SciLifeLab, Uppsala University, Uppsala SE- 75108, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>März</LastName><ForeName>Winfried</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Synlab Academy, Synlab Services GmbH, Oberer Eselsberg 45, Ulm 89081, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koenig</LastName><ForeName>Wolfgang</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine II-Cardiology, University of Ulm Medical Centre, Albert-Einstein-Allee 23, Ulm 89081, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lieb</LastName><ForeName>Wolfgang</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology and Biobank popgen, Christian-Albrechts University, Niemannsweg 11, Kiel 24105, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Loos</LastName><ForeName>Ruth J F</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Mindich Child Health and Development Institute, Ichan School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Yongmei</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Internal Medicine Department, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1053, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Snieder</LastName><ForeName>Harold</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pramstaller</LastName><ForeName>Peter P</ForeName><Initials>PP</Initials><AffiliationInfo><Affiliation>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Via Galvani 31, Bolzano 39100, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Neurology, General Central Hospital, Via Lorenz Bohler 5, Bolzano 39100, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Neurology, University of Lübeck, Ratzeburger Allee 160, Lübeck 23538, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parsa</LastName><ForeName>Afshin</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>University of Maryland Medical School, Division of Nephrology, 685 W. Baltimore Street, MSTF 314, Baltimore, Maryland 21201, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Connell</LastName><ForeName>Jeffrey R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Susztak</LastName><ForeName>Katalin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 405B Clinical Research Building, Philadelphia, Pennsylvania 19104-4539, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hamet</LastName><ForeName>Pavel</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>CRCHUM, University of Montreal, CHUM Research Center, Technopôle Angus, 900 Saint-Denis, Montreal, Québec, Canada H2X 0A9.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tremblay</LastName><ForeName>Johanne</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>CRCHUM, University of Montreal, CHUM Research Center, Technopôle Angus, 900 Saint-Denis, Montreal, Québec, Canada H2X 0A9.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Boer</LastName><ForeName>Ian H</ForeName><Initials>IH</Initials><AffiliationInfo><Affiliation>Kidney Research Institute, University of Washington, Box 359606, 325 9th Avenue, Seattle, Washington 98104, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Böger</LastName><ForeName>Carsten A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, Regensburg 93053, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goessling</LastName><ForeName>Wolfram</ForeName><Initials>W</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-9972-1569</Identifier><AffiliationInfo><Affiliation>Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, New Research Building77 Avenue Louis Pasteur, Room 458, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chasman</LastName><ForeName>Daniel I</ForeName><Initials>DI</Initials><AffiliationInfo><Affiliation>Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, Massachusetts 02215, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Harvard Medical School, 900 Commonwealth Avenue East, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Köttgen</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Internal Medicine IV, University Hospital Freiburg, Berliner Allee 29, Freiburg 79110, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kao</LastName><ForeName>W H Linda</ForeName><Initials>WH</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Welch Center for Prevention, Epidemiology and Clinical Research, 2024 East Monument St, Suite 2-600, Baltimore, Maryland 21287, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>Caroline S</ForeName><Initials>CS</Initials><AffiliationInfo><Affiliation>NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Endocrinology, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01 MD009055</GrantID><Acronym>MD</Acronym><Agency>NIMHD NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 DK058845</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>K12 RR023250</GrantID><Acronym>RR</Acronym><Agency>NCRR NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01DK090311</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>RG/13/13/30194</GrantID><Agency>British Heart 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HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 DK089256</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>FS/14/55/30806</GrantID><Agency>British Heart Foundation</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/K006584/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/K013351/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>HHSN268201100009C</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 HL117078</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 HL087641</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>G0600237</GrantID><Agency>Medical Research 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States</Country></Grant><Grant><GrantID>R24OD017870</GrantID><Acronym>OD</Acronym><Agency>NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>01</Month><Day>21</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Nat Commun</MedlineTA><NlmUniqueID>101528555</NlmUniqueID><ISSNLinking>2041-1723</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Nat Rev Nephrol. 2016 Apr;12(4):196</RefSource><PMID Version="1">26853277</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2011 Oct 6;478(7367):103-9</RefSource><PMID 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ValidYN="Y"><LastName>Parker</LastName><ForeName>Alex N</ForeName><Initials>AN</Initials></Investigator><Investigator ValidYN="Y"><LastName>Peden</LastName><ForeName>John F</ForeName><Initials>JF</Initials></Investigator><Investigator ValidYN="Y"><LastName>Peltonen</LastName><ForeName>Leena</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Perola</LastName><ForeName>Markus</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pihur</LastName><ForeName>Vasyl</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Platou</LastName><ForeName>Carl G P</ForeName><Initials>CG</Initials></Investigator><Investigator ValidYN="Y"><LastName>Plump</LastName><ForeName>Andrew</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Prabhakaran</LastName><ForeName>Dorairajan</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Psaty</LastName><ForeName>Bruce M</ForeName><Initials>BM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Raffel</LastName><ForeName>Leslie J</ForeName><Initials>LJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rao</LastName><ForeName>Dabeeru C</ForeName><Initials>DC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rasheed</LastName><ForeName>Asif</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ricceri</LastName><ForeName>Fulvio</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rice</LastName><ForeName>Kenneth M</ForeName><Initials>KM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rosengren</LastName><ForeName>Annika</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rotter</LastName><ForeName>Jerome I</ForeName><Initials>JI</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rudock</LastName><ForeName>Megan E</ForeName><Initials>ME</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sõber</LastName><ForeName>Siim</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Salako</LastName><ForeName>Tunde</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Saleheen</LastName><ForeName>Danish</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Salomaa</LastName><ForeName>Veikko</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Samani</LastName><ForeName>Nilesh J</ForeName><Initials>NJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schwartz</LastName><ForeName>Steven M</ForeName><Initials>SM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schwarz</LastName><ForeName>Peter E H</ForeName><Initials>PE</Initials></Investigator><Investigator ValidYN="Y"><LastName>Scott</LastName><ForeName>Laura J</ForeName><Initials>LJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Scott</LastName><ForeName>James</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Scuteri</LastName><ForeName>Angelo</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sehmi</LastName><ForeName>Joban S</ForeName><Initials>JS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Seielstad</LastName><ForeName>Mark</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Seshadri</LastName><ForeName>Sudha</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sharma</LastName><ForeName>Pankaj</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Shaw-Hawkins</LastName><ForeName>Sue</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Shi</LastName><ForeName>Gang</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Shrine</LastName><ForeName>Nick R G</ForeName><Initials>NR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sijbrands</LastName><ForeName>Eric J G</ForeName><Initials>EJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sim</LastName><ForeName>Xueling</ForeName><Initials>X</Initials></Investigator><Investigator ValidYN="Y"><LastName>Singleton</LastName><ForeName>Andrew</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sjögren</LastName><ForeName>Marketa</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Smith</LastName><ForeName>Nicholas L</ForeName><Initials>NL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Soler Artigas</LastName><ForeName>Maria</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Spector</LastName><ForeName>Tim D</ForeName><Initials>TD</Initials></Investigator><Investigator ValidYN="Y"><LastName>Staessen</LastName><ForeName>Jan A</ForeName><Initials>JA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Stancakova</LastName><ForeName>Alena</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Steinle</LastName><ForeName>Nanette I</ForeName><Initials>NI</Initials></Investigator><Investigator ValidYN="Y"><LastName>Strachan</LastName><ForeName>David P</ForeName><Initials>DP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Stringham</LastName><ForeName>Heather M</ForeName><Initials>HM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sun</LastName><ForeName>Yan V</ForeName><Initials>YV</Initials></Investigator><Investigator ValidYN="Y"><LastName>Swift</LastName><ForeName>Amy J</ForeName><Initials>AJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tabara</LastName><ForeName>Yasuharu</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tai</LastName><ForeName>E-Shyong</ForeName><Initials>ES</Initials></Investigator><Investigator ValidYN="Y"><LastName>Talmud</LastName><ForeName>Philippa J</ForeName><Initials>PJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Taylor</LastName><ForeName>Andrew</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Terzic</LastName><ForeName>Janos</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Thelle</LastName><ForeName>Dag S</ForeName><Initials>DS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tobin</LastName><ForeName>Martin D</ForeName><Initials>MD</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tomaszewski</LastName><ForeName>Maciej</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tripathy</LastName><ForeName>Vikal</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tuomilehto</LastName><ForeName>Jaakko</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tzoulaki</LastName><ForeName>Ioanna</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Uda</LastName><ForeName>Manuela</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ueshima</LastName><ForeName>Hirotsugu</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Uiterwaal</LastName><ForeName>Cuno S P M</ForeName><Initials>CS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Umemura</LastName><ForeName>Satoshi</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>van der Harst</LastName><ForeName>Pim</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>van der Schouw</LastName><ForeName>Yvonne T</ForeName><Initials>YT</Initials></Investigator><Investigator ValidYN="Y"><LastName>van 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H</ForeName><Initials>JH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zelenika</LastName><ForeName>Diana</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zhai</LastName><ForeName>Guangju</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zhang</LastName><ForeName>Weihua</ForeName><Initials>W</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zhang</LastName><ForeName>Feng</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zhao</LastName><ForeName>Jing Hua</ForeName><Initials>JH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zhu</LastName><ForeName>Haidong</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zhu</LastName><ForeName>Xiaofeng</ForeName><Initials>X</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zitting</LastName><ForeName>Paavo</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zukowska-Szczechowska</LastName><ForeName>Ewa</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Okada</LastName><ForeName>Yukinori</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wu</LastName><ForeName>Jer-Yuarn</ForeName><Initials>JY</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gu</LastName><ForeName>Dongfeng</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Takeuchi</LastName><ForeName>Fumihiko</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Takahashi</LastName><ForeName>Atsushi</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Maeda</LastName><ForeName>Shiro</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tsunoda</LastName><ForeName>Tatsuhiko</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chen</LastName><ForeName>Peng</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lim</LastName><ForeName>Su-Chi</ForeName><Initials>SC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wong</LastName><ForeName>Tien-Yin</ForeName><Initials>TY</Initials></Investigator><Investigator ValidYN="Y"><LastName>Liu</LastName><ForeName>Jianjun</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Young</LastName><ForeName>Terri L</ForeName><Initials>TL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Aung</LastName><ForeName>Tin</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Teo</LastName><ForeName>Yik-Ying</ForeName><Initials>YY</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kim</LastName><ForeName>Young Jin</ForeName><Initials>YJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kang</LastName><ForeName>Daehee</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chen</LastName><ForeName>Chien-Hsiun</ForeName><Initials>CH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tsai</LastName><ForeName>Fuu-Jen</ForeName><Initials>FJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chang</LastName><ForeName>Li-Ching</ForeName><Initials>LC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Fann</LastName><ForeName>S-J Cathy</ForeName><Initials>SJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mei</LastName><ForeName>Hao</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hixson</LastName><ForeName>James E</ForeName><Initials>JE</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chen</LastName><ForeName>Shufeng</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Katsuya</LastName><ForeName>Tomohiro</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Isono</LastName><ForeName>Masato</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Albrecht</LastName><ForeName>Eva</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yamamoto</LastName><ForeName>Kazuhiko</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kubo</LastName><ForeName>Michiaki</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nakamura</LastName><ForeName>Yusuke</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kamatani</LastName><ForeName>Naoyuki</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kato</LastName><ForeName>Norihiro</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>He</LastName><ForeName>Jiang</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chen</LastName><ForeName>Yuan-Tsong</ForeName><Initials>YT</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tanaka</LastName><ForeName>Toshihiro</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Reilly</LastName><ForeName>Muredach P</ForeName><Initials>MP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schunkert</LastName><ForeName>Heribert</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Assimes</LastName><ForeName>Themistocles L</ForeName><Initials>TL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hall</LastName><ForeName>Alistair</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hengstenberg</LastName><ForeName>Christian</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>König</LastName><ForeName>Inke R</ForeName><Initials>IR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Laaksonen</LastName><ForeName>Reijo</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>McPherson</LastName><ForeName>Ruth</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Thompson</LastName><ForeName>John R</ForeName><Initials>JR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Thorsteinsdottir</LastName><ForeName>Unnur</ForeName><Initials>U</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ziegler</LastName><ForeName>Andreas</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Absher</LastName><ForeName>Devin</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chen</LastName><ForeName>Li</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cupples</LastName><ForeName>L Adrienne</ForeName><Initials>LA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Halperin</LastName><ForeName>Eran</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Li</LastName><ForeName>Mingyao</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Musunuru</LastName><ForeName>Kiran</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Preuss</LastName><ForeName>Michael</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schillert</LastName><ForeName>Arne</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Thorleifsson</LastName><ForeName>Gudmar</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wells</LastName><ForeName>George A</ForeName><Initials>GA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Holm</LastName><ForeName>Hilma</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Roberts</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Stewart</LastName><ForeName>Alexandre F R</ForeName><Initials>AF</Initials></Investigator><Investigator ValidYN="Y"><LastName>Fortmann</LastName><ForeName>Stephen</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Go</LastName><ForeName>Alan</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hlatky</LastName><ForeName>Mark</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Iribarren</LastName><ForeName>Carlos</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Knowles</LastName><ForeName>Joshua</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Myers</LastName><ForeName>Richard</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Quertermous</LastName><ForeName>Thomas</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sidney</LastName><ForeName>Steven</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Risch</LastName><ForeName>Neil</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tang</LastName><ForeName>Hua</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Blankenberg</LastName><ForeName>Stefan</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schnabel</LastName><ForeName>Renate</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sinning</LastName><ForeName>Christoph</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lackner</LastName><ForeName>Karl J</ForeName><Initials>KJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tiret</LastName><ForeName>Laurence</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nicaud</LastName><ForeName>Viviane</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cambien</LastName><ForeName>Francois</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bickel</LastName><ForeName>Christoph</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rupprecht</LastName><ForeName>Hans J</ForeName><Initials>HJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Perret</LastName><ForeName>Claire</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Proust</LastName><ForeName>Carole</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Münzel</LastName><ForeName>Thomas 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