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Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.

Identifieur interne : 001F35 ( PubMed/Corpus ); précédent : 001F34; suivant : 001F36

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.

Auteurs : Chiea Chuen Khor ; Tan Do ; Hongyan Jia ; Masakazu Nakano ; Ronnie George ; Khaled Abu-Amero ; Roopam Duvesh ; Li Jia Chen ; Zheng Li ; Monisha E. Nongpiur ; Shamira A. Perera ; Chunyan Qiao ; Hon-Tym Wong ; Hiroshi Sakai ; Mônica Barbosa De Melo ; Mei-Chin Lee ; Anita S. Chan ; Yaakub Azhany ; Thi Lam Huong Dao ; Yoko Ikeda ; Rodolfo A. Perez-Grossmann ; Tomasz Zarnowski ; Alexander C. Day ; Jost B. Jonas ; Pancy O S. Tam ; Tuan Anh Tran ; Humaira Ayub ; Farah Akhtar ; Shazia Micheal ; Paul T K. Chew ; Leyla A. Aljasim ; Tanuj Dada ; Tam Thi Luu ; Mona S. Awadalla ; Naris Kitnarong ; Boonsong Wanichwecharungruang ; Yee Yee Aung ; Jelinar Mohamed-Noor ; Saravanan Vijayan ; Sripriya Sarangapani ; Rahat Husain ; Aliza Jap ; Mani Baskaran ; David Goh ; Daniel H. Su ; Huaizhou Wang ; Vernon K. Yong ; Leonard W. Yip ; Tuyet Bach Trinh ; Manchima Makornwattana ; Thanh Thu Nguyen ; Edgar U. Leuenberger ; Ki-Ho Park ; Widya Artini Wiyogo ; Rajesh S. Kumar ; Celso Tello ; Yasuo Kurimoto ; Suman S. Thapa ; Kessara Pathanapitoon ; John F. Salmon ; Yong Ho Sohn ; Antonio Fea ; Mineo Ozaki ; Jimmy S M. Lai ; Visanee Tantisevi ; Chaw Chaw Khaing ; Takanori Mizoguchi ; Satoko Nakano ; Chan-Yun Kim ; Guangxian Tang ; Sujie Fan ; Renyi Wu ; Hailin Meng ; Thi Thuy Giang Nguyen ; Tien Dat Tran ; Morio Ueno ; Jose Maria Martinez ; Norlina Ramli ; Yin Mon Aung ; Rigo Daniel Reyes ; Stephen A. Vernon ; Seng Kheong Fang ; Zhicheng Xie ; Xiao Yin Chen ; Jia Nee Foo ; Kar Seng Sim ; Tina T. Wong ; Desmond T. Quek ; Rengaraj Venkatesh ; Srinivasan Kavitha ; Subbiah R. Krishnadas ; Nagaswamy Soumittra ; Balekudaru Shantha ; Boon-Ang Lim ; Jeanne Ogle ; José P C. De Vasconcellos ; Vital P. Costa ; Ricardo Y. Abe ; Bruno B. De Souza ; Chelvin C. Sng ; Maria C. Aquino ; Ewa Kosior-Jarecka ; Guillermo Barreto Fong ; Vania Castro Tamanaja ; Ricardo Fujita ; Yuzhen Jiang ; Naushin Waseem ; Sancy Low ; Huan Nguyen Pham ; Sami Al-Shahwan ; E Randy Craven ; Muhammad Imran Khan ; Rrima Dada ; Kuldeep Mohanty ; Muneeb A. Faiq ; Alex W. Hewitt ; Kathryn P. Burdon ; Eng Hui Gan ; Anuwat Prutthipongsit ; Thipnapa Patthanathamrongkasem ; Mary Ann T. Catacutan ; Irene R. Felarca ; Chona S. Liao ; Emma Rusmayani ; Vira Wardhana Istiantoro ; Giulia Consolandi ; Giulia Pignata ; Carlo Lavia ; Prin Rojanapongpun ; Lerprat Mangkornkanokpong ; Sunee Chansangpetch ; Jonathan C H. Chan ; Bonnie N K. Choy ; Jennifer W H. Shum ; Hlaing May Than ; Khin Thida Oo ; Aye Thi Han ; Victor H. Yong ; Xiao-Yu Ng ; Shuang Ru Goh ; Yaan Fun Chong ; Martin L. Hibberd ; Mark Seielstad ; Eileen Png ; Sarah J. Dunstan ; Nguyen Van Vinh Chau ; Jinxin Bei ; Yi Xin Zeng ; Abhilasha Karkey ; Buddha Basnyat ; Francesca Pasutto ; Daniela Paoli ; Paolo Frezzotti ; Jie Jin Wang ; Paul Mitchell ; John H. Fingert ; R Rand Allingham ; Michael A. Hauser ; Soon Thye Lim ; Soo Hong Chew ; Richard P. Ebstein ; Anavaj Sakuntabhai ; Kyu Hyung Park ; Jeeyun Ahn ; Greet Boland ; Harm Snippe ; Richard Stead ; Raquel Quino ; Su Nyunt Zaw ; Urszula Lukasik ; Rohit Shetty ; Mimiwati Zahari ; Hyoung Won Bae ; Nay Lin Oo ; Toshiaki Kubota ; Anita Manassakorn ; Wing Lau Ho ; Laura Dallorto ; Young Hoon Hwang ; Christine A. Kiire ; Masako Kuroda ; Zeiras Eka Djamal ; Jovell Ian M. Peregrino ; Arkasubhra Ghosh ; Jin Wook Jeoung ; Tung S. Hoan ; Nuttamon Srisamran ; Thayanithi Sandragasu ; Saw Htoo Set ; Vi Huyen Doan ; Shomi S. Bhattacharya ; Ching-Lin Ho ; Donald T. Tan ; Ramanjit Sihota ; Seng-Chee Loon ; Kazuhiko Mori ; Shigeru Kinoshita ; Anneke I Den Hollander ; Raheel Qamar ; Ya-Xing Wang ; Yik Y. Teo ; E-Shyong Tai ; Curt Hartleben-Matkin ; David Lozano-Giral ; Seang Mei Saw ; Ching-Yu Cheng ; Juan C. Zenteno ; Chi Pui Pang ; Huong T T. Bui ; Owen Hee ; Jamie E. Craig ; Deepak P. Edward ; Michiko Yonahara ; Jamil Miguel Neto ; Maria L. Guevara-Fujita ; Liang Xu ; Robert Ritch ; Ahmad Tajudin Liza-Sharmini ; Tien Y. Wong ; Saleh Al-Obeidan ; Nhu Hon Do ; Periasamy Sundaresan ; Clement C. Tham ; Paul J. Foster ; Lingam Vijaya ; Kei Tashiro ; Eranga N. Vithana ; Ningli Wang ; Tin Aung

Source :

RBID : pubmed:27064256

English descriptors

Abstract

Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We conducted a genome-wide association study (GWAS) followed by replication in a combined total of 10,503 PACG cases and 29,567 controls drawn from 24 countries across Asia, Australia, Europe, North America, and South America. We observed significant evidence of disease association at five new genetic loci upon meta-analysis of all patient collections. These loci are at EPDR1 rs3816415 (odds ratio (OR) = 1.24, P = 5.94 × 10(-15)), CHAT rs1258267 (OR = 1.22, P = 2.85 × 10(-16)), GLIS3 rs736893 (OR = 1.18, P = 1.43 × 10(-14)), FERMT2 rs7494379 (OR = 1.14, P = 3.43 × 10(-11)), and DPM2-FAM102A rs3739821 (OR = 1.15, P = 8.32 × 10(-12)). We also confirmed significant association at three previously described loci (P < 5 × 10(-8) for each sentinel SNP at PLEKHA7, COL11A1, and PCMTD1-ST18), providing new insights into the biology of PACG.

DOI: 10.1038/ng.3540
PubMed: 27064256

Links to Exploration step

pubmed:27064256

Le document en format XML

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<name sortKey="Li, Zheng" sort="Li, Zheng" uniqKey="Li Z" first="Zheng" last="Li">Zheng Li</name>
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<name sortKey="Qiao, Chunyan" sort="Qiao, Chunyan" uniqKey="Qiao C" first="Chunyan" last="Qiao">Chunyan Qiao</name>
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<name sortKey="Sakai, Hiroshi" sort="Sakai, Hiroshi" uniqKey="Sakai H" first="Hiroshi" last="Sakai">Hiroshi Sakai</name>
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<nlm:affiliation>Department of Ophthalmology, University of the Ryukyus, Okinawa, Nishihara, Japan.</nlm:affiliation>
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<name sortKey="Barbosa De Melo, Monica" sort="Barbosa De Melo, Monica" uniqKey="Barbosa De Melo M" first="Mônica" last="Barbosa De Melo">Mônica Barbosa De Melo</name>
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<nlm:affiliation>Center of Molecular Biology and Genetic Engineering, University of Campinas, Campinas, Brazil.</nlm:affiliation>
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<name sortKey="Lee, Mei Chin" sort="Lee, Mei Chin" uniqKey="Lee M" first="Mei-Chin" last="Lee">Mei-Chin Lee</name>
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<name sortKey="Chan, Anita S" sort="Chan, Anita S" uniqKey="Chan A" first="Anita S" last="Chan">Anita S. Chan</name>
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<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
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<name sortKey="Azhany, Yaakub" sort="Azhany, Yaakub" uniqKey="Azhany Y" first="Yaakub" last="Azhany">Yaakub Azhany</name>
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<nlm:affiliation>Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia and Hospital Universiti Sains Malaysia, Kelantan, Malaysia.</nlm:affiliation>
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<name sortKey="Dao, Thi Lam Huong" sort="Dao, Thi Lam Huong" uniqKey="Dao T" first="Thi Lam Huong" last="Dao">Thi Lam Huong Dao</name>
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<nlm:affiliation>Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.</nlm:affiliation>
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<author>
<name sortKey="Ikeda, Yoko" sort="Ikeda, Yoko" uniqKey="Ikeda Y" first="Yoko" last="Ikeda">Yoko Ikeda</name>
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<nlm:affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</nlm:affiliation>
</affiliation>
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<author>
<name sortKey="Perez Grossmann, Rodolfo A" sort="Perez Grossmann, Rodolfo A" uniqKey="Perez Grossmann R" first="Rodolfo A" last="Perez-Grossmann">Rodolfo A. Perez-Grossmann</name>
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<nlm:affiliation>Instituto de Glaucoma y Catarata, Lima, Peru.</nlm:affiliation>
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<author>
<name sortKey="Zarnowski, Tomasz" sort="Zarnowski, Tomasz" uniqKey="Zarnowski T" first="Tomasz" last="Zarnowski">Tomasz Zarnowski</name>
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<nlm:affiliation>Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.</nlm:affiliation>
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</author>
<author>
<name sortKey="Day, Alexander C" sort="Day, Alexander C" uniqKey="Day A" first="Alexander C" last="Day">Alexander C. Day</name>
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<nlm:affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</nlm:affiliation>
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<name sortKey="Jonas, Jost B" sort="Jonas, Jost B" uniqKey="Jonas J" first="Jost B" last="Jonas">Jost B. Jonas</name>
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<nlm:affiliation>Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht Karls University Heidelberg, Heidelberg, Germany.</nlm:affiliation>
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<name sortKey="Tam, Pancy O S" sort="Tam, Pancy O S" uniqKey="Tam P" first="Pancy O S" last="Tam">Pancy O S. Tam</name>
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<nlm:affiliation>Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.</nlm:affiliation>
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<name sortKey="Tran, Tuan Anh" sort="Tran, Tuan Anh" uniqKey="Tran T" first="Tuan Anh" last="Tran">Tuan Anh Tran</name>
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<nlm:affiliation>Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.</nlm:affiliation>
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<name sortKey="Ayub, Humaira" sort="Ayub, Humaira" uniqKey="Ayub H" first="Humaira" last="Ayub">Humaira Ayub</name>
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<nlm:affiliation>Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan.</nlm:affiliation>
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<author>
<name sortKey="Akhtar, Farah" sort="Akhtar, Farah" uniqKey="Akhtar F" first="Farah" last="Akhtar">Farah Akhtar</name>
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<nlm:affiliation>Pakistan Institute of Ophthalmology, Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Micheal, Shazia" sort="Micheal, Shazia" uniqKey="Micheal S" first="Shazia" last="Micheal">Shazia Micheal</name>
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<nlm:affiliation>Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chew, Paul T K" sort="Chew, Paul T K" uniqKey="Chew P" first="Paul T K" last="Chew">Paul T K. Chew</name>
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<nlm:affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Aljasim, Leyla A" sort="Aljasim, Leyla A" uniqKey="Aljasim L" first="Leyla A" last="Aljasim">Leyla A. Aljasim</name>
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<nlm:affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
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<author>
<name sortKey="Dada, Tanuj" sort="Dada, Tanuj" uniqKey="Dada T" first="Tanuj" last="Dada">Tanuj Dada</name>
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<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Luu, Tam Thi" sort="Luu, Tam Thi" uniqKey="Luu T" first="Tam Thi" last="Luu">Tam Thi Luu</name>
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<nlm:affiliation>Department of Glaucoma, Da Nang Eye Hospital, Da Nang City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Awadalla, Mona S" sort="Awadalla, Mona S" uniqKey="Awadalla M" first="Mona S" last="Awadalla">Mona S. Awadalla</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kitnarong, Naris" sort="Kitnarong, Naris" uniqKey="Kitnarong N" first="Naris" last="Kitnarong">Naris Kitnarong</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wanichwecharungruang, Boonsong" sort="Wanichwecharungruang, Boonsong" uniqKey="Wanichwecharungruang B" first="Boonsong" last="Wanichwecharungruang">Boonsong Wanichwecharungruang</name>
<affiliation>
<nlm:affiliation>Glaucoma Services, Department of Ophthalmology, Rajavithi Hospital, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Aung, Yee Yee" sort="Aung, Yee Yee" uniqKey="Aung Y" first="Yee Yee" last="Aung">Yee Yee Aung</name>
<affiliation>
<nlm:affiliation>Mandalay Eye Department, Mandalay Eye ENT Hospital, University of Medicine Mandalay, Mandalay, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mohamed Noor, Jelinar" sort="Mohamed Noor, Jelinar" uniqKey="Mohamed Noor J" first="Jelinar" last="Mohamed-Noor">Jelinar Mohamed-Noor</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vijayan, Saravanan" sort="Vijayan, Saravanan" uniqKey="Vijayan S" first="Saravanan" last="Vijayan">Saravanan Vijayan</name>
<affiliation>
<nlm:affiliation>Department of Genetics, Aravind Medical Research Foundation, Madurai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sarangapani, Sripriya" sort="Sarangapani, Sripriya" uniqKey="Sarangapani S" first="Sripriya" last="Sarangapani">Sripriya Sarangapani</name>
<affiliation>
<nlm:affiliation>Vision Research Foundation, Sankara Nethralaya, Chennai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Husain, Rahat" sort="Husain, Rahat" uniqKey="Husain R" first="Rahat" last="Husain">Rahat Husain</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Jap, Aliza" sort="Jap, Aliza" uniqKey="Jap A" first="Aliza" last="Jap">Aliza Jap</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Baskaran, Mani" sort="Baskaran, Mani" uniqKey="Baskaran M" first="Mani" last="Baskaran">Mani Baskaran</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Goh, David" sort="Goh, David" uniqKey="Goh D" first="David" last="Goh">David Goh</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Su, Daniel H" sort="Su, Daniel H" uniqKey="Su D" first="Daniel H" last="Su">Daniel H. Su</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wang, Huaizhou" sort="Wang, Huaizhou" uniqKey="Wang H" first="Huaizhou" last="Wang">Huaizhou Wang</name>
<affiliation>
<nlm:affiliation>Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Yong, Vernon K" sort="Yong, Vernon K" uniqKey="Yong V" first="Vernon K" last="Yong">Vernon K. Yong</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Yip, Leonard W" sort="Yip, Leonard W" uniqKey="Yip L" first="Leonard W" last="Yip">Leonard W. Yip</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Trinh, Tuyet Bach" sort="Trinh, Tuyet Bach" uniqKey="Trinh T" first="Tuyet Bach" last="Trinh">Tuyet Bach Trinh</name>
<affiliation>
<nlm:affiliation>Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Makornwattana, Manchima" sort="Makornwattana, Manchima" uniqKey="Makornwattana M" first="Manchima" last="Makornwattana">Manchima Makornwattana</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Nguyen, Thanh Thu" sort="Nguyen, Thanh Thu" uniqKey="Nguyen T" first="Thanh Thu" last="Nguyen">Thanh Thu Nguyen</name>
<affiliation>
<nlm:affiliation>Eye Department, Viet Tiep General Hospital, Hai Phong, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Leuenberger, Edgar U" sort="Leuenberger, Edgar U" uniqKey="Leuenberger E" first="Edgar U" last="Leuenberger">Edgar U. Leuenberger</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Park, Ki Ho" sort="Park, Ki Ho" uniqKey="Park K" first="Ki-Ho" last="Park">Ki-Ho Park</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wiyogo, Widya Artini" sort="Wiyogo, Widya Artini" uniqKey="Wiyogo W" first="Widya Artini" last="Wiyogo">Widya Artini Wiyogo</name>
<affiliation>
<nlm:affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kumar, Rajesh S" sort="Kumar, Rajesh S" uniqKey="Kumar R" first="Rajesh S" last="Kumar">Rajesh S. Kumar</name>
<affiliation>
<nlm:affiliation>Narayana Nethralaya Eye Hospital, Bangalore, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tello, Celso" sort="Tello, Celso" uniqKey="Tello C" first="Celso" last="Tello">Celso Tello</name>
<affiliation>
<nlm:affiliation>Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kurimoto, Yasuo" sort="Kurimoto, Yasuo" uniqKey="Kurimoto Y" first="Yasuo" last="Kurimoto">Yasuo Kurimoto</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kobe City Medical Center General Hospital, Kobe, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Thapa, Suman S" sort="Thapa, Suman S" uniqKey="Thapa S" first="Suman S" last="Thapa">Suman S. Thapa</name>
<affiliation>
<nlm:affiliation>Nepal Glaucoma Eye Clinic, Tilganga Institute of Ophthalmology, Kathmandu, Nepal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pathanapitoon, Kessara" sort="Pathanapitoon, Kessara" uniqKey="Pathanapitoon K" first="Kessara" last="Pathanapitoon">Kessara Pathanapitoon</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Salmon, John F" sort="Salmon, John F" uniqKey="Salmon J" first="John F" last="Salmon">John F. Salmon</name>
<affiliation>
<nlm:affiliation>Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sohn, Yong Ho" sort="Sohn, Yong Ho" uniqKey="Sohn Y" first="Yong Ho" last="Sohn">Yong Ho Sohn</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fea, Antonio" sort="Fea, Antonio" uniqKey="Fea A" first="Antonio" last="Fea">Antonio Fea</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ozaki, Mineo" sort="Ozaki, Mineo" uniqKey="Ozaki M" first="Mineo" last="Ozaki">Mineo Ozaki</name>
<affiliation>
<nlm:affiliation>Ozaki Eye Hospital, Hyuga, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lai, Jimmy S M" sort="Lai, Jimmy S M" uniqKey="Lai J" first="Jimmy S M" last="Lai">Jimmy S M. Lai</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tantisevi, Visanee" sort="Tantisevi, Visanee" uniqKey="Tantisevi V" first="Visanee" last="Tantisevi">Visanee Tantisevi</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Khaing, Chaw Chaw" sort="Khaing, Chaw Chaw" uniqKey="Khaing C" first="Chaw Chaw" last="Khaing">Chaw Chaw Khaing</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, No. 1 Defence Services General Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mizoguchi, Takanori" sort="Mizoguchi, Takanori" uniqKey="Mizoguchi T" first="Takanori" last="Mizoguchi">Takanori Mizoguchi</name>
<affiliation>
<nlm:affiliation>Mizoguchi Eye Hospital, Sasebo, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Nakano, Satoko" sort="Nakano, Satoko" uniqKey="Nakano S" first="Satoko" last="Nakano">Satoko Nakano</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Oita University Faculty of Medicine, Oita, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kim, Chan Yun" sort="Kim, Chan Yun" uniqKey="Kim C" first="Chan-Yun" last="Kim">Chan-Yun Kim</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tang, Guangxian" sort="Tang, Guangxian" uniqKey="Tang G" first="Guangxian" last="Tang">Guangxian Tang</name>
<affiliation>
<nlm:affiliation>Shijiazhuang First Eye Hospital, Shijiazhuang, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fan, Sujie" sort="Fan, Sujie" uniqKey="Fan S" first="Sujie" last="Fan">Sujie Fan</name>
<affiliation>
<nlm:affiliation>Handan Eye Hospital, Handan, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wu, Renyi" sort="Wu, Renyi" uniqKey="Wu R" first="Renyi" last="Wu">Renyi Wu</name>
<affiliation>
<nlm:affiliation>Eye Institute and Affiliated Xiamen Eye Center, Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Xiamen, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Meng, Hailin" sort="Meng, Hailin" uniqKey="Meng H" first="Hailin" last="Meng">Hailin Meng</name>
<affiliation>
<nlm:affiliation>Anyang Eye Hospital, Anyang, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Nguyen, Thi Thuy Giang" sort="Nguyen, Thi Thuy Giang" uniqKey="Nguyen T" first="Thi Thuy Giang" last="Nguyen">Thi Thuy Giang Nguyen</name>
<affiliation>
<nlm:affiliation>Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tran, Tien Dat" sort="Tran, Tien Dat" uniqKey="Tran T" first="Tien Dat" last="Tran">Tien Dat Tran</name>
<affiliation>
<nlm:affiliation>Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ueno, Morio" sort="Ueno, Morio" uniqKey="Ueno M" first="Morio" last="Ueno">Morio Ueno</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Martinez, Jose Maria" sort="Martinez, Jose Maria" uniqKey="Martinez J" first="Jose Maria" last="Martinez">Jose Maria Martinez</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Pasig City General Hospital, Pasig City, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ramli, Norlina" sort="Ramli, Norlina" uniqKey="Ramli N" first="Norlina" last="Ramli">Norlina Ramli</name>
<affiliation>
<nlm:affiliation>University of Malaya, Eye Research Centre, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Aung, Yin Mon" sort="Aung, Yin Mon" uniqKey="Aung Y" first="Yin Mon" last="Aung">Yin Mon Aung</name>
<affiliation>
<nlm:affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Reyes, Rigo Daniel" sort="Reyes, Rigo Daniel" uniqKey="Reyes R" first="Rigo Daniel" last="Reyes">Rigo Daniel Reyes</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology/Glaucoma Section, Asian Hospital and Medical Center, Muntinlupa City, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vernon, Stephen A" sort="Vernon, Stephen A" uniqKey="Vernon S" first="Stephen A" last="Vernon">Stephen A. Vernon</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University Hospital Nottingham, University of Nottingham, Nottingham, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fang, Seng Kheong" sort="Fang, Seng Kheong" uniqKey="Fang S" first="Seng Kheong" last="Fang">Seng Kheong Fang</name>
<affiliation>
<nlm:affiliation>International Specialist Eye Centre, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Xie, Zhicheng" sort="Xie, Zhicheng" uniqKey="Xie Z" first="Zhicheng" last="Xie">Zhicheng Xie</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chen, Xiao Yin" sort="Chen, Xiao Yin" uniqKey="Chen X" first="Xiao Yin" last="Chen">Xiao Yin Chen</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Foo, Jia Nee" sort="Foo, Jia Nee" uniqKey="Foo J" first="Jia Nee" last="Foo">Jia Nee Foo</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sim, Kar Seng" sort="Sim, Kar Seng" uniqKey="Sim K" first="Kar Seng" last="Sim">Kar Seng Sim</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wong, Tina T" sort="Wong, Tina T" uniqKey="Wong T" first="Tina T" last="Wong">Tina T. Wong</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Quek, Desmond T" sort="Quek, Desmond T" uniqKey="Quek D" first="Desmond T" last="Quek">Desmond T. Quek</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Venkatesh, Rengaraj" sort="Venkatesh, Rengaraj" uniqKey="Venkatesh R" first="Rengaraj" last="Venkatesh">Rengaraj Venkatesh</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Pondicherry, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kavitha, Srinivasan" sort="Kavitha, Srinivasan" uniqKey="Kavitha S" first="Srinivasan" last="Kavitha">Srinivasan Kavitha</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Pondicherry, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Krishnadas, Subbiah R" sort="Krishnadas, Subbiah R" uniqKey="Krishnadas S" first="Subbiah R" last="Krishnadas">Subbiah R. Krishnadas</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Soumittra, Nagaswamy" sort="Soumittra, Nagaswamy" uniqKey="Soumittra N" first="Nagaswamy" last="Soumittra">Nagaswamy Soumittra</name>
<affiliation>
<nlm:affiliation>Vision Research Foundation, Sankara Nethralaya, Chennai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Shantha, Balekudaru" sort="Shantha, Balekudaru" uniqKey="Shantha B" first="Balekudaru" last="Shantha">Balekudaru Shantha</name>
<affiliation>
<nlm:affiliation>Jadhavbhai Nathamal Singhvi Department of Glaucoma, Medical Research Foundation, Sankara Nethralaya, Chennai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lim, Boon Ang" sort="Lim, Boon Ang" uniqKey="Lim B" first="Boon-Ang" last="Lim">Boon-Ang Lim</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ogle, Jeanne" sort="Ogle, Jeanne" uniqKey="Ogle J" first="Jeanne" last="Ogle">Jeanne Ogle</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="De Vasconcellos, Jose P C" sort="De Vasconcellos, Jose P C" uniqKey="De Vasconcellos J" first="José P C" last="De Vasconcellos">José P C. De Vasconcellos</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Costa, Vital P" sort="Costa, Vital P" uniqKey="Costa V" first="Vital P" last="Costa">Vital P. Costa</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Abe, Ricardo Y" sort="Abe, Ricardo Y" uniqKey="Abe R" first="Ricardo Y" last="Abe">Ricardo Y. Abe</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="De Souza, Bruno B" sort="De Souza, Bruno B" uniqKey="De Souza B" first="Bruno B" last="De Souza">Bruno B. De Souza</name>
<affiliation>
<nlm:affiliation>Center of Molecular Biology and Genetic Engineering, University of Campinas, Campinas, Brazil.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sng, Chelvin C" sort="Sng, Chelvin C" uniqKey="Sng C" first="Chelvin C" last="Sng">Chelvin C. Sng</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Aquino, Maria C" sort="Aquino, Maria C" uniqKey="Aquino M" first="Maria C" last="Aquino">Maria C. Aquino</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kosior Jarecka, Ewa" sort="Kosior Jarecka, Ewa" uniqKey="Kosior Jarecka E" first="Ewa" last="Kosior-Jarecka">Ewa Kosior-Jarecka</name>
<affiliation>
<nlm:affiliation>Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fong, Guillermo Barreto" sort="Fong, Guillermo Barreto" uniqKey="Fong G" first="Guillermo Barreto" last="Fong">Guillermo Barreto Fong</name>
<affiliation>
<nlm:affiliation>Instituto de Ciencias Médicas, Lima, Peru.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tamanaja, Vania Castro" sort="Tamanaja, Vania Castro" uniqKey="Tamanaja V" first="Vania Castro" last="Tamanaja">Vania Castro Tamanaja</name>
<affiliation>
<nlm:affiliation>Hospital Nacional Arzobispo Loayza, Lima, Peru.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fujita, Ricardo" sort="Fujita, Ricardo" uniqKey="Fujita R" first="Ricardo" last="Fujita">Ricardo Fujita</name>
<affiliation>
<nlm:affiliation>Centro de Genética y Biología Molecular, Universidad de San Martín de Porres, Lima, Peru.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Jiang, Yuzhen" sort="Jiang, Yuzhen" uniqKey="Jiang Y" first="Yuzhen" last="Jiang">Yuzhen Jiang</name>
<affiliation>
<nlm:affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Waseem, Naushin" sort="Waseem, Naushin" uniqKey="Waseem N" first="Naushin" last="Waseem">Naushin Waseem</name>
<affiliation>
<nlm:affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Low, Sancy" sort="Low, Sancy" uniqKey="Low S" first="Sancy" last="Low">Sancy Low</name>
<affiliation>
<nlm:affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pham, Huan Nguyen" sort="Pham, Huan Nguyen" uniqKey="Pham H" first="Huan Nguyen" last="Pham">Huan Nguyen Pham</name>
<affiliation>
<nlm:affiliation>Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Al Shahwan, Sami" sort="Al Shahwan, Sami" uniqKey="Al Shahwan S" first="Sami" last="Al-Shahwan">Sami Al-Shahwan</name>
<affiliation>
<nlm:affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Craven, E Randy" sort="Craven, E Randy" uniqKey="Craven E" first="E Randy" last="Craven">E Randy Craven</name>
<affiliation>
<nlm:affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Khan, Muhammad Imran" sort="Khan, Muhammad Imran" uniqKey="Khan M" first="Muhammad Imran" last="Khan">Muhammad Imran Khan</name>
<affiliation>
<nlm:affiliation>Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Dada, Rrima" sort="Dada, Rrima" uniqKey="Dada R" first="Rrima" last="Dada">Rrima Dada</name>
<affiliation>
<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mohanty, Kuldeep" sort="Mohanty, Kuldeep" uniqKey="Mohanty K" first="Kuldeep" last="Mohanty">Kuldeep Mohanty</name>
<affiliation>
<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Faiq, Muneeb A" sort="Faiq, Muneeb A" uniqKey="Faiq M" first="Muneeb A" last="Faiq">Muneeb A. Faiq</name>
<affiliation>
<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hewitt, Alex W" sort="Hewitt, Alex W" uniqKey="Hewitt A" first="Alex W" last="Hewitt">Alex W. Hewitt</name>
<affiliation>
<nlm:affiliation>Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Burdon, Kathryn P" sort="Burdon, Kathryn P" uniqKey="Burdon K" first="Kathryn P" last="Burdon">Kathryn P. Burdon</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gan, Eng Hui" sort="Gan, Eng Hui" uniqKey="Gan E" first="Eng Hui" last="Gan">Eng Hui Gan</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Prutthipongsit, Anuwat" sort="Prutthipongsit, Anuwat" uniqKey="Prutthipongsit A" first="Anuwat" last="Prutthipongsit">Anuwat Prutthipongsit</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Patthanathamrongkasem, Thipnapa" sort="Patthanathamrongkasem, Thipnapa" uniqKey="Patthanathamrongkasem T" first="Thipnapa" last="Patthanathamrongkasem">Thipnapa Patthanathamrongkasem</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Catacutan, Mary Ann T" sort="Catacutan, Mary Ann T" uniqKey="Catacutan M" first="Mary Ann T" last="Catacutan">Mary Ann T. Catacutan</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Felarca, Irene R" sort="Felarca, Irene R" uniqKey="Felarca I" first="Irene R" last="Felarca">Irene R. Felarca</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liao, Chona S" sort="Liao, Chona S" uniqKey="Liao C" first="Chona S" last="Liao">Chona S. Liao</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Rusmayani, Emma" sort="Rusmayani, Emma" uniqKey="Rusmayani E" first="Emma" last="Rusmayani">Emma Rusmayani</name>
<affiliation>
<nlm:affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Istiantoro, Vira Wardhana" sort="Istiantoro, Vira Wardhana" uniqKey="Istiantoro V" first="Vira Wardhana" last="Istiantoro">Vira Wardhana Istiantoro</name>
<affiliation>
<nlm:affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Consolandi, Giulia" sort="Consolandi, Giulia" uniqKey="Consolandi G" first="Giulia" last="Consolandi">Giulia Consolandi</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pignata, Giulia" sort="Pignata, Giulia" uniqKey="Pignata G" first="Giulia" last="Pignata">Giulia Pignata</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lavia, Carlo" sort="Lavia, Carlo" uniqKey="Lavia C" first="Carlo" last="Lavia">Carlo Lavia</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Rojanapongpun, Prin" sort="Rojanapongpun, Prin" uniqKey="Rojanapongpun P" first="Prin" last="Rojanapongpun">Prin Rojanapongpun</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mangkornkanokpong, Lerprat" sort="Mangkornkanokpong, Lerprat" uniqKey="Mangkornkanokpong L" first="Lerprat" last="Mangkornkanokpong">Lerprat Mangkornkanokpong</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chansangpetch, Sunee" sort="Chansangpetch, Sunee" uniqKey="Chansangpetch S" first="Sunee" last="Chansangpetch">Sunee Chansangpetch</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chan, Jonathan C H" sort="Chan, Jonathan C H" uniqKey="Chan J" first="Jonathan C H" last="Chan">Jonathan C H. Chan</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Queen Mary Hospital, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Choy, Bonnie N K" sort="Choy, Bonnie N K" uniqKey="Choy B" first="Bonnie N K" last="Choy">Bonnie N K. Choy</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Shum, Jennifer W H" sort="Shum, Jennifer W H" uniqKey="Shum J" first="Jennifer W H" last="Shum">Jennifer W H. Shum</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Than, Hlaing May" sort="Than, Hlaing May" uniqKey="Than H" first="Hlaing May" last="Than">Hlaing May Than</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, North Okkalarpa General Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Oo, Khin Thida" sort="Oo, Khin Thida" uniqKey="Oo K" first="Khin Thida" last="Oo">Khin Thida Oo</name>
<affiliation>
<nlm:affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Han, Aye Thi" sort="Han, Aye Thi" uniqKey="Han A" first="Aye Thi" last="Han">Aye Thi Han</name>
<affiliation>
<nlm:affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Yong, Victor H" sort="Yong, Victor H" uniqKey="Yong V" first="Victor H" last="Yong">Victor H. Yong</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ng, Xiao Yu" sort="Ng, Xiao Yu" uniqKey="Ng X" first="Xiao-Yu" last="Ng">Xiao-Yu Ng</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Goh, Shuang Ru" sort="Goh, Shuang Ru" uniqKey="Goh S" first="Shuang Ru" last="Goh">Shuang Ru Goh</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chong, Yaan Fun" sort="Chong, Yaan Fun" uniqKey="Chong Y" first="Yaan Fun" last="Chong">Yaan Fun Chong</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hibberd, Martin L" sort="Hibberd, Martin L" uniqKey="Hibberd M" first="Martin L" last="Hibberd">Martin L. Hibberd</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Seielstad, Mark" sort="Seielstad, Mark" uniqKey="Seielstad M" first="Mark" last="Seielstad">Mark Seielstad</name>
<affiliation>
<nlm:affiliation>Institute for Human Genetics, University of California, San Francisco, San Francisco, California, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Png, Eileen" sort="Png, Eileen" uniqKey="Png E" first="Eileen" last="Png">Eileen Png</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Dunstan, Sarah J" sort="Dunstan, Sarah J" uniqKey="Dunstan S" first="Sarah J" last="Dunstan">Sarah J. Dunstan</name>
<affiliation>
<nlm:affiliation>Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chau, Nguyen Van Vinh" sort="Chau, Nguyen Van Vinh" uniqKey="Chau N" first="Nguyen Van Vinh" last="Chau">Nguyen Van Vinh Chau</name>
<affiliation>
<nlm:affiliation>Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bei, Jinxin" sort="Bei, Jinxin" uniqKey="Bei J" first="Jinxin" last="Bei">Jinxin Bei</name>
<affiliation>
<nlm:affiliation>Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zeng, Yi Xin" sort="Zeng, Yi Xin" uniqKey="Zeng Y" first="Yi Xin" last="Zeng">Yi Xin Zeng</name>
<affiliation>
<nlm:affiliation>Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Karkey, Abhilasha" sort="Karkey, Abhilasha" uniqKey="Karkey A" first="Abhilasha" last="Karkey">Abhilasha Karkey</name>
<affiliation>
<nlm:affiliation>Oxford University Clinical Research Unit-Nepal, Patan Academy of Health Sciences, Patan Hospital, Patan, Nepal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Basnyat, Buddha" sort="Basnyat, Buddha" uniqKey="Basnyat B" first="Buddha" last="Basnyat">Buddha Basnyat</name>
<affiliation>
<nlm:affiliation>Oxford University Clinical Research Unit-Nepal, Patan Academy of Health Sciences, Patan Hospital, Patan, Nepal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pasutto, Francesca" sort="Pasutto, Francesca" uniqKey="Pasutto F" first="Francesca" last="Pasutto">Francesca Pasutto</name>
<affiliation>
<nlm:affiliation>Institute of Human Genetics, Friedrich Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Paoli, Daniela" sort="Paoli, Daniela" uniqKey="Paoli D" first="Daniela" last="Paoli">Daniela Paoli</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Monfalcone Hospital, Gorizia, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Frezzotti, Paolo" sort="Frezzotti, Paolo" uniqKey="Frezzotti P" first="Paolo" last="Frezzotti">Paolo Frezzotti</name>
<affiliation>
<nlm:affiliation>Department of Surgery, Section of Ophthalmology, University of Siena, Siena, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wang, Jie Jin" sort="Wang, Jie Jin" uniqKey="Wang J" first="Jie Jin" last="Wang">Jie Jin Wang</name>
<affiliation>
<nlm:affiliation>Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mitchell, Paul" sort="Mitchell, Paul" uniqKey="Mitchell P" first="Paul" last="Mitchell">Paul Mitchell</name>
<affiliation>
<nlm:affiliation>Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fingert, John H" sort="Fingert, John H" uniqKey="Fingert J" first="John H" last="Fingert">John H. Fingert</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Allingham, R Rand" sort="Allingham, R Rand" uniqKey="Allingham R" first="R Rand" last="Allingham">R Rand Allingham</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hauser, Michael A" sort="Hauser, Michael A" uniqKey="Hauser M" first="Michael A" last="Hauser">Michael A. Hauser</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lim, Soon Thye" sort="Lim, Soon Thye" uniqKey="Lim S" first="Soon Thye" last="Lim">Soon Thye Lim</name>
<affiliation>
<nlm:affiliation>Division of Medical Oncology, National Cancer Centre, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chew, Soo Hong" sort="Chew, Soo Hong" uniqKey="Chew S" first="Soo Hong" last="Chew">Soo Hong Chew</name>
<affiliation>
<nlm:affiliation>Department of Economics, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ebstein, Richard P" sort="Ebstein, Richard P" uniqKey="Ebstein R" first="Richard P" last="Ebstein">Richard P. Ebstein</name>
<affiliation>
<nlm:affiliation>Department of Psychology, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sakuntabhai, Anavaj" sort="Sakuntabhai, Anavaj" uniqKey="Sakuntabhai A" first="Anavaj" last="Sakuntabhai">Anavaj Sakuntabhai</name>
<affiliation>
<nlm:affiliation>Institut Pasteur, Functional Genetics of Infectious Diseases Unit, Department of Genomes and Genetics, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Park, Kyu Hyung" sort="Park, Kyu Hyung" uniqKey="Park K" first="Kyu Hyung" last="Park">Kyu Hyung Park</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggi, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ahn, Jeeyun" sort="Ahn, Jeeyun" uniqKey="Ahn J" first="Jeeyun" last="Ahn">Jeeyun Ahn</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Boland, Greet" sort="Boland, Greet" uniqKey="Boland G" first="Greet" last="Boland">Greet Boland</name>
<affiliation>
<nlm:affiliation>Department of Medical Microbiology and Virology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Snippe, Harm" sort="Snippe, Harm" uniqKey="Snippe H" first="Harm" last="Snippe">Harm Snippe</name>
<affiliation>
<nlm:affiliation>Department of Medical Microbiology and Virology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Stead, Richard" sort="Stead, Richard" uniqKey="Stead R" first="Richard" last="Stead">Richard Stead</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University Hospital Nottingham, University of Nottingham, Nottingham, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Quino, Raquel" sort="Quino, Raquel" uniqKey="Quino R" first="Raquel" last="Quino">Raquel Quino</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology/Glaucoma Section, Asian Hospital and Medical Center, Muntinlupa City, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zaw, Su Nyunt" sort="Zaw, Su Nyunt" uniqKey="Zaw S" first="Su Nyunt" last="Zaw">Su Nyunt Zaw</name>
<affiliation>
<nlm:affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lukasik, Urszula" sort="Lukasik, Urszula" uniqKey="Lukasik U" first="Urszula" last="Lukasik">Urszula Lukasik</name>
<affiliation>
<nlm:affiliation>Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Shetty, Rohit" sort="Shetty, Rohit" uniqKey="Shetty R" first="Rohit" last="Shetty">Rohit Shetty</name>
<affiliation>
<nlm:affiliation>Narayana Nethralaya Eye Hospital, Bangalore, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zahari, Mimiwati" sort="Zahari, Mimiwati" uniqKey="Zahari M" first="Mimiwati" last="Zahari">Mimiwati Zahari</name>
<affiliation>
<nlm:affiliation>University of Malaya, Eye Research Centre, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bae, Hyoung Won" sort="Bae, Hyoung Won" uniqKey="Bae H" first="Hyoung Won" last="Bae">Hyoung Won Bae</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Oo, Nay Lin" sort="Oo, Nay Lin" uniqKey="Oo N" first="Nay Lin" last="Oo">Nay Lin Oo</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, No. 1 Defence Services General Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kubota, Toshiaki" sort="Kubota, Toshiaki" uniqKey="Kubota T" first="Toshiaki" last="Kubota">Toshiaki Kubota</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Oita University Faculty of Medicine, Oita, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Manassakorn, Anita" sort="Manassakorn, Anita" uniqKey="Manassakorn A" first="Anita" last="Manassakorn">Anita Manassakorn</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ho, Wing Lau" sort="Ho, Wing Lau" uniqKey="Ho W" first="Wing Lau" last="Ho">Wing Lau Ho</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Dallorto, Laura" sort="Dallorto, Laura" uniqKey="Dallorto L" first="Laura" last="Dallorto">Laura Dallorto</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hwang, Young Hoon" sort="Hwang, Young Hoon" uniqKey="Hwang Y" first="Young Hoon" last="Hwang">Young Hoon Hwang</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kiire, Christine A" sort="Kiire, Christine A" uniqKey="Kiire C" first="Christine A" last="Kiire">Christine A. Kiire</name>
<affiliation>
<nlm:affiliation>Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kuroda, Masako" sort="Kuroda, Masako" uniqKey="Kuroda M" first="Masako" last="Kuroda">Masako Kuroda</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kobe City Medical Center General Hospital, Kobe, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Djamal, Zeiras Eka" sort="Djamal, Zeiras Eka" uniqKey="Djamal Z" first="Zeiras Eka" last="Djamal">Zeiras Eka Djamal</name>
<affiliation>
<nlm:affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Peregrino, Jovell Ian M" sort="Peregrino, Jovell Ian M" uniqKey="Peregrino J" first="Jovell Ian M" last="Peregrino">Jovell Ian M. Peregrino</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ghosh, Arkasubhra" sort="Ghosh, Arkasubhra" uniqKey="Ghosh A" first="Arkasubhra" last="Ghosh">Arkasubhra Ghosh</name>
<affiliation>
<nlm:affiliation>Narayana Nethralaya Eye Hospital, Bangalore, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Jeoung, Jin Wook" sort="Jeoung, Jin Wook" uniqKey="Jeoung J" first="Jin Wook" last="Jeoung">Jin Wook Jeoung</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hoan, Tung S" sort="Hoan, Tung S" uniqKey="Hoan T" first="Tung S" last="Hoan">Tung S. Hoan</name>
<affiliation>
<nlm:affiliation>Eye Department, Viet Tiep General Hospital, Hai Phong, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Srisamran, Nuttamon" sort="Srisamran, Nuttamon" uniqKey="Srisamran N" first="Nuttamon" last="Srisamran">Nuttamon Srisamran</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sandragasu, Thayanithi" sort="Sandragasu, Thayanithi" uniqKey="Sandragasu T" first="Thayanithi" last="Sandragasu">Thayanithi Sandragasu</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Set, Saw Htoo" sort="Set, Saw Htoo" uniqKey="Set S" first="Saw Htoo" last="Set">Saw Htoo Set</name>
<affiliation>
<nlm:affiliation>Mandalay Eye Department, Mandalay Eye ENT Hospital, University of Medicine Mandalay, Mandalay, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Doan, Vi Huyen" sort="Doan, Vi Huyen" uniqKey="Doan V" first="Vi Huyen" last="Doan">Vi Huyen Doan</name>
<affiliation>
<nlm:affiliation>Department of Glaucoma, Da Nang Eye Hospital, Da Nang City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bhattacharya, Shomi S" sort="Bhattacharya, Shomi S" uniqKey="Bhattacharya S" first="Shomi S" last="Bhattacharya">Shomi S. Bhattacharya</name>
<affiliation>
<nlm:affiliation>Division of Genetics, UCL Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ho, Ching Lin" sort="Ho, Ching Lin" uniqKey="Ho C" first="Ching-Lin" last="Ho">Ching-Lin Ho</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tan, Donald T" sort="Tan, Donald T" uniqKey="Tan D" first="Donald T" last="Tan">Donald T. Tan</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sihota, Ramanjit" sort="Sihota, Ramanjit" uniqKey="Sihota R" first="Ramanjit" last="Sihota">Ramanjit Sihota</name>
<affiliation>
<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Loon, Seng Chee" sort="Loon, Seng Chee" uniqKey="Loon S" first="Seng-Chee" last="Loon">Seng-Chee Loon</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mori, Kazuhiko" sort="Mori, Kazuhiko" uniqKey="Mori K" first="Kazuhiko" last="Mori">Kazuhiko Mori</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kinoshita, Shigeru" sort="Kinoshita, Shigeru" uniqKey="Kinoshita S" first="Shigeru" last="Kinoshita">Shigeru Kinoshita</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hollander, Anneke I Den" sort="Hollander, Anneke I Den" uniqKey="Hollander A" first="Anneke I Den" last="Hollander">Anneke I Den Hollander</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Qamar, Raheel" sort="Qamar, Raheel" uniqKey="Qamar R" first="Raheel" last="Qamar">Raheel Qamar</name>
<affiliation>
<nlm:affiliation>Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wang, Ya Xing" sort="Wang, Ya Xing" uniqKey="Wang Y" first="Ya-Xing" last="Wang">Ya-Xing Wang</name>
<affiliation>
<nlm:affiliation>Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Teo, Yik Y" sort="Teo, Yik Y" uniqKey="Teo Y" first="Yik Y" last="Teo">Yik Y. Teo</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tai, E Shyong" sort="Tai, E Shyong" uniqKey="Tai E" first="E-Shyong" last="Tai">E-Shyong Tai</name>
<affiliation>
<nlm:affiliation>Saw Swee Hock School of Public Health, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hartleben Matkin, Curt" sort="Hartleben Matkin, Curt" uniqKey="Hartleben Matkin C" first="Curt" last="Hartleben-Matkin">Curt Hartleben-Matkin</name>
<affiliation>
<nlm:affiliation>Department of Glaucoma, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lozano Giral, David" sort="Lozano Giral, David" uniqKey="Lozano Giral D" first="David" last="Lozano-Giral">David Lozano-Giral</name>
<affiliation>
<nlm:affiliation>Department of Genetics, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Saw, Seang Mei" sort="Saw, Seang Mei" uniqKey="Saw S" first="Seang Mei" last="Saw">Seang Mei Saw</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cheng, Ching Yu" sort="Cheng, Ching Yu" uniqKey="Cheng C" first="Ching-Yu" last="Cheng">Ching-Yu Cheng</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zenteno, Juan C" sort="Zenteno, Juan C" uniqKey="Zenteno J" first="Juan C" last="Zenteno">Juan C. Zenteno</name>
<affiliation>
<nlm:affiliation>Department of Genetics, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pang, Chi Pui" sort="Pang, Chi Pui" uniqKey="Pang C" first="Chi Pui" last="Pang">Chi Pui Pang</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
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<idno type="doi">10.1038/ng.3540</idno>
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</author>
<author>
<name sortKey="Park, Ki Ho" sort="Park, Ki Ho" uniqKey="Park K" first="Ki-Ho" last="Park">Ki-Ho Park</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wiyogo, Widya Artini" sort="Wiyogo, Widya Artini" uniqKey="Wiyogo W" first="Widya Artini" last="Wiyogo">Widya Artini Wiyogo</name>
<affiliation>
<nlm:affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kumar, Rajesh S" sort="Kumar, Rajesh S" uniqKey="Kumar R" first="Rajesh S" last="Kumar">Rajesh S. Kumar</name>
<affiliation>
<nlm:affiliation>Narayana Nethralaya Eye Hospital, Bangalore, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tello, Celso" sort="Tello, Celso" uniqKey="Tello C" first="Celso" last="Tello">Celso Tello</name>
<affiliation>
<nlm:affiliation>Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kurimoto, Yasuo" sort="Kurimoto, Yasuo" uniqKey="Kurimoto Y" first="Yasuo" last="Kurimoto">Yasuo Kurimoto</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kobe City Medical Center General Hospital, Kobe, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Thapa, Suman S" sort="Thapa, Suman S" uniqKey="Thapa S" first="Suman S" last="Thapa">Suman S. Thapa</name>
<affiliation>
<nlm:affiliation>Nepal Glaucoma Eye Clinic, Tilganga Institute of Ophthalmology, Kathmandu, Nepal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pathanapitoon, Kessara" sort="Pathanapitoon, Kessara" uniqKey="Pathanapitoon K" first="Kessara" last="Pathanapitoon">Kessara Pathanapitoon</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Salmon, John F" sort="Salmon, John F" uniqKey="Salmon J" first="John F" last="Salmon">John F. Salmon</name>
<affiliation>
<nlm:affiliation>Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sohn, Yong Ho" sort="Sohn, Yong Ho" uniqKey="Sohn Y" first="Yong Ho" last="Sohn">Yong Ho Sohn</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fea, Antonio" sort="Fea, Antonio" uniqKey="Fea A" first="Antonio" last="Fea">Antonio Fea</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ozaki, Mineo" sort="Ozaki, Mineo" uniqKey="Ozaki M" first="Mineo" last="Ozaki">Mineo Ozaki</name>
<affiliation>
<nlm:affiliation>Ozaki Eye Hospital, Hyuga, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lai, Jimmy S M" sort="Lai, Jimmy S M" uniqKey="Lai J" first="Jimmy S M" last="Lai">Jimmy S M. Lai</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tantisevi, Visanee" sort="Tantisevi, Visanee" uniqKey="Tantisevi V" first="Visanee" last="Tantisevi">Visanee Tantisevi</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Khaing, Chaw Chaw" sort="Khaing, Chaw Chaw" uniqKey="Khaing C" first="Chaw Chaw" last="Khaing">Chaw Chaw Khaing</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, No. 1 Defence Services General Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mizoguchi, Takanori" sort="Mizoguchi, Takanori" uniqKey="Mizoguchi T" first="Takanori" last="Mizoguchi">Takanori Mizoguchi</name>
<affiliation>
<nlm:affiliation>Mizoguchi Eye Hospital, Sasebo, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Nakano, Satoko" sort="Nakano, Satoko" uniqKey="Nakano S" first="Satoko" last="Nakano">Satoko Nakano</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Oita University Faculty of Medicine, Oita, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kim, Chan Yun" sort="Kim, Chan Yun" uniqKey="Kim C" first="Chan-Yun" last="Kim">Chan-Yun Kim</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tang, Guangxian" sort="Tang, Guangxian" uniqKey="Tang G" first="Guangxian" last="Tang">Guangxian Tang</name>
<affiliation>
<nlm:affiliation>Shijiazhuang First Eye Hospital, Shijiazhuang, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fan, Sujie" sort="Fan, Sujie" uniqKey="Fan S" first="Sujie" last="Fan">Sujie Fan</name>
<affiliation>
<nlm:affiliation>Handan Eye Hospital, Handan, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wu, Renyi" sort="Wu, Renyi" uniqKey="Wu R" first="Renyi" last="Wu">Renyi Wu</name>
<affiliation>
<nlm:affiliation>Eye Institute and Affiliated Xiamen Eye Center, Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Xiamen, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Meng, Hailin" sort="Meng, Hailin" uniqKey="Meng H" first="Hailin" last="Meng">Hailin Meng</name>
<affiliation>
<nlm:affiliation>Anyang Eye Hospital, Anyang, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Nguyen, Thi Thuy Giang" sort="Nguyen, Thi Thuy Giang" uniqKey="Nguyen T" first="Thi Thuy Giang" last="Nguyen">Thi Thuy Giang Nguyen</name>
<affiliation>
<nlm:affiliation>Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tran, Tien Dat" sort="Tran, Tien Dat" uniqKey="Tran T" first="Tien Dat" last="Tran">Tien Dat Tran</name>
<affiliation>
<nlm:affiliation>Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ueno, Morio" sort="Ueno, Morio" uniqKey="Ueno M" first="Morio" last="Ueno">Morio Ueno</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Martinez, Jose Maria" sort="Martinez, Jose Maria" uniqKey="Martinez J" first="Jose Maria" last="Martinez">Jose Maria Martinez</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Pasig City General Hospital, Pasig City, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ramli, Norlina" sort="Ramli, Norlina" uniqKey="Ramli N" first="Norlina" last="Ramli">Norlina Ramli</name>
<affiliation>
<nlm:affiliation>University of Malaya, Eye Research Centre, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Aung, Yin Mon" sort="Aung, Yin Mon" uniqKey="Aung Y" first="Yin Mon" last="Aung">Yin Mon Aung</name>
<affiliation>
<nlm:affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Reyes, Rigo Daniel" sort="Reyes, Rigo Daniel" uniqKey="Reyes R" first="Rigo Daniel" last="Reyes">Rigo Daniel Reyes</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology/Glaucoma Section, Asian Hospital and Medical Center, Muntinlupa City, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vernon, Stephen A" sort="Vernon, Stephen A" uniqKey="Vernon S" first="Stephen A" last="Vernon">Stephen A. Vernon</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University Hospital Nottingham, University of Nottingham, Nottingham, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fang, Seng Kheong" sort="Fang, Seng Kheong" uniqKey="Fang S" first="Seng Kheong" last="Fang">Seng Kheong Fang</name>
<affiliation>
<nlm:affiliation>International Specialist Eye Centre, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Xie, Zhicheng" sort="Xie, Zhicheng" uniqKey="Xie Z" first="Zhicheng" last="Xie">Zhicheng Xie</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chen, Xiao Yin" sort="Chen, Xiao Yin" uniqKey="Chen X" first="Xiao Yin" last="Chen">Xiao Yin Chen</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Foo, Jia Nee" sort="Foo, Jia Nee" uniqKey="Foo J" first="Jia Nee" last="Foo">Jia Nee Foo</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sim, Kar Seng" sort="Sim, Kar Seng" uniqKey="Sim K" first="Kar Seng" last="Sim">Kar Seng Sim</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wong, Tina T" sort="Wong, Tina T" uniqKey="Wong T" first="Tina T" last="Wong">Tina T. Wong</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Quek, Desmond T" sort="Quek, Desmond T" uniqKey="Quek D" first="Desmond T" last="Quek">Desmond T. Quek</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Venkatesh, Rengaraj" sort="Venkatesh, Rengaraj" uniqKey="Venkatesh R" first="Rengaraj" last="Venkatesh">Rengaraj Venkatesh</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Pondicherry, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kavitha, Srinivasan" sort="Kavitha, Srinivasan" uniqKey="Kavitha S" first="Srinivasan" last="Kavitha">Srinivasan Kavitha</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Pondicherry, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Krishnadas, Subbiah R" sort="Krishnadas, Subbiah R" uniqKey="Krishnadas S" first="Subbiah R" last="Krishnadas">Subbiah R. Krishnadas</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Soumittra, Nagaswamy" sort="Soumittra, Nagaswamy" uniqKey="Soumittra N" first="Nagaswamy" last="Soumittra">Nagaswamy Soumittra</name>
<affiliation>
<nlm:affiliation>Vision Research Foundation, Sankara Nethralaya, Chennai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Shantha, Balekudaru" sort="Shantha, Balekudaru" uniqKey="Shantha B" first="Balekudaru" last="Shantha">Balekudaru Shantha</name>
<affiliation>
<nlm:affiliation>Jadhavbhai Nathamal Singhvi Department of Glaucoma, Medical Research Foundation, Sankara Nethralaya, Chennai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lim, Boon Ang" sort="Lim, Boon Ang" uniqKey="Lim B" first="Boon-Ang" last="Lim">Boon-Ang Lim</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ogle, Jeanne" sort="Ogle, Jeanne" uniqKey="Ogle J" first="Jeanne" last="Ogle">Jeanne Ogle</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="De Vasconcellos, Jose P C" sort="De Vasconcellos, Jose P C" uniqKey="De Vasconcellos J" first="José P C" last="De Vasconcellos">José P C. De Vasconcellos</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Costa, Vital P" sort="Costa, Vital P" uniqKey="Costa V" first="Vital P" last="Costa">Vital P. Costa</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Abe, Ricardo Y" sort="Abe, Ricardo Y" uniqKey="Abe R" first="Ricardo Y" last="Abe">Ricardo Y. Abe</name>
<affiliation>
<nlm:affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="De Souza, Bruno B" sort="De Souza, Bruno B" uniqKey="De Souza B" first="Bruno B" last="De Souza">Bruno B. De Souza</name>
<affiliation>
<nlm:affiliation>Center of Molecular Biology and Genetic Engineering, University of Campinas, Campinas, Brazil.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sng, Chelvin C" sort="Sng, Chelvin C" uniqKey="Sng C" first="Chelvin C" last="Sng">Chelvin C. Sng</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Aquino, Maria C" sort="Aquino, Maria C" uniqKey="Aquino M" first="Maria C" last="Aquino">Maria C. Aquino</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kosior Jarecka, Ewa" sort="Kosior Jarecka, Ewa" uniqKey="Kosior Jarecka E" first="Ewa" last="Kosior-Jarecka">Ewa Kosior-Jarecka</name>
<affiliation>
<nlm:affiliation>Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fong, Guillermo Barreto" sort="Fong, Guillermo Barreto" uniqKey="Fong G" first="Guillermo Barreto" last="Fong">Guillermo Barreto Fong</name>
<affiliation>
<nlm:affiliation>Instituto de Ciencias Médicas, Lima, Peru.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tamanaja, Vania Castro" sort="Tamanaja, Vania Castro" uniqKey="Tamanaja V" first="Vania Castro" last="Tamanaja">Vania Castro Tamanaja</name>
<affiliation>
<nlm:affiliation>Hospital Nacional Arzobispo Loayza, Lima, Peru.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fujita, Ricardo" sort="Fujita, Ricardo" uniqKey="Fujita R" first="Ricardo" last="Fujita">Ricardo Fujita</name>
<affiliation>
<nlm:affiliation>Centro de Genética y Biología Molecular, Universidad de San Martín de Porres, Lima, Peru.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Jiang, Yuzhen" sort="Jiang, Yuzhen" uniqKey="Jiang Y" first="Yuzhen" last="Jiang">Yuzhen Jiang</name>
<affiliation>
<nlm:affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Waseem, Naushin" sort="Waseem, Naushin" uniqKey="Waseem N" first="Naushin" last="Waseem">Naushin Waseem</name>
<affiliation>
<nlm:affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Low, Sancy" sort="Low, Sancy" uniqKey="Low S" first="Sancy" last="Low">Sancy Low</name>
<affiliation>
<nlm:affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pham, Huan Nguyen" sort="Pham, Huan Nguyen" uniqKey="Pham H" first="Huan Nguyen" last="Pham">Huan Nguyen Pham</name>
<affiliation>
<nlm:affiliation>Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Al Shahwan, Sami" sort="Al Shahwan, Sami" uniqKey="Al Shahwan S" first="Sami" last="Al-Shahwan">Sami Al-Shahwan</name>
<affiliation>
<nlm:affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Craven, E Randy" sort="Craven, E Randy" uniqKey="Craven E" first="E Randy" last="Craven">E Randy Craven</name>
<affiliation>
<nlm:affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Khan, Muhammad Imran" sort="Khan, Muhammad Imran" uniqKey="Khan M" first="Muhammad Imran" last="Khan">Muhammad Imran Khan</name>
<affiliation>
<nlm:affiliation>Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Dada, Rrima" sort="Dada, Rrima" uniqKey="Dada R" first="Rrima" last="Dada">Rrima Dada</name>
<affiliation>
<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mohanty, Kuldeep" sort="Mohanty, Kuldeep" uniqKey="Mohanty K" first="Kuldeep" last="Mohanty">Kuldeep Mohanty</name>
<affiliation>
<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Faiq, Muneeb A" sort="Faiq, Muneeb A" uniqKey="Faiq M" first="Muneeb A" last="Faiq">Muneeb A. Faiq</name>
<affiliation>
<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hewitt, Alex W" sort="Hewitt, Alex W" uniqKey="Hewitt A" first="Alex W" last="Hewitt">Alex W. Hewitt</name>
<affiliation>
<nlm:affiliation>Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Burdon, Kathryn P" sort="Burdon, Kathryn P" uniqKey="Burdon K" first="Kathryn P" last="Burdon">Kathryn P. Burdon</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gan, Eng Hui" sort="Gan, Eng Hui" uniqKey="Gan E" first="Eng Hui" last="Gan">Eng Hui Gan</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Prutthipongsit, Anuwat" sort="Prutthipongsit, Anuwat" uniqKey="Prutthipongsit A" first="Anuwat" last="Prutthipongsit">Anuwat Prutthipongsit</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Patthanathamrongkasem, Thipnapa" sort="Patthanathamrongkasem, Thipnapa" uniqKey="Patthanathamrongkasem T" first="Thipnapa" last="Patthanathamrongkasem">Thipnapa Patthanathamrongkasem</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Catacutan, Mary Ann T" sort="Catacutan, Mary Ann T" uniqKey="Catacutan M" first="Mary Ann T" last="Catacutan">Mary Ann T. Catacutan</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Felarca, Irene R" sort="Felarca, Irene R" uniqKey="Felarca I" first="Irene R" last="Felarca">Irene R. Felarca</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liao, Chona S" sort="Liao, Chona S" uniqKey="Liao C" first="Chona S" last="Liao">Chona S. Liao</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Rusmayani, Emma" sort="Rusmayani, Emma" uniqKey="Rusmayani E" first="Emma" last="Rusmayani">Emma Rusmayani</name>
<affiliation>
<nlm:affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Istiantoro, Vira Wardhana" sort="Istiantoro, Vira Wardhana" uniqKey="Istiantoro V" first="Vira Wardhana" last="Istiantoro">Vira Wardhana Istiantoro</name>
<affiliation>
<nlm:affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Consolandi, Giulia" sort="Consolandi, Giulia" uniqKey="Consolandi G" first="Giulia" last="Consolandi">Giulia Consolandi</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pignata, Giulia" sort="Pignata, Giulia" uniqKey="Pignata G" first="Giulia" last="Pignata">Giulia Pignata</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lavia, Carlo" sort="Lavia, Carlo" uniqKey="Lavia C" first="Carlo" last="Lavia">Carlo Lavia</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Rojanapongpun, Prin" sort="Rojanapongpun, Prin" uniqKey="Rojanapongpun P" first="Prin" last="Rojanapongpun">Prin Rojanapongpun</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mangkornkanokpong, Lerprat" sort="Mangkornkanokpong, Lerprat" uniqKey="Mangkornkanokpong L" first="Lerprat" last="Mangkornkanokpong">Lerprat Mangkornkanokpong</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chansangpetch, Sunee" sort="Chansangpetch, Sunee" uniqKey="Chansangpetch S" first="Sunee" last="Chansangpetch">Sunee Chansangpetch</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chan, Jonathan C H" sort="Chan, Jonathan C H" uniqKey="Chan J" first="Jonathan C H" last="Chan">Jonathan C H. Chan</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Queen Mary Hospital, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Choy, Bonnie N K" sort="Choy, Bonnie N K" uniqKey="Choy B" first="Bonnie N K" last="Choy">Bonnie N K. Choy</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Shum, Jennifer W H" sort="Shum, Jennifer W H" uniqKey="Shum J" first="Jennifer W H" last="Shum">Jennifer W H. Shum</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Than, Hlaing May" sort="Than, Hlaing May" uniqKey="Than H" first="Hlaing May" last="Than">Hlaing May Than</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, North Okkalarpa General Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Oo, Khin Thida" sort="Oo, Khin Thida" uniqKey="Oo K" first="Khin Thida" last="Oo">Khin Thida Oo</name>
<affiliation>
<nlm:affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Han, Aye Thi" sort="Han, Aye Thi" uniqKey="Han A" first="Aye Thi" last="Han">Aye Thi Han</name>
<affiliation>
<nlm:affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Yong, Victor H" sort="Yong, Victor H" uniqKey="Yong V" first="Victor H" last="Yong">Victor H. Yong</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ng, Xiao Yu" sort="Ng, Xiao Yu" uniqKey="Ng X" first="Xiao-Yu" last="Ng">Xiao-Yu Ng</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Goh, Shuang Ru" sort="Goh, Shuang Ru" uniqKey="Goh S" first="Shuang Ru" last="Goh">Shuang Ru Goh</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chong, Yaan Fun" sort="Chong, Yaan Fun" uniqKey="Chong Y" first="Yaan Fun" last="Chong">Yaan Fun Chong</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hibberd, Martin L" sort="Hibberd, Martin L" uniqKey="Hibberd M" first="Martin L" last="Hibberd">Martin L. Hibberd</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Seielstad, Mark" sort="Seielstad, Mark" uniqKey="Seielstad M" first="Mark" last="Seielstad">Mark Seielstad</name>
<affiliation>
<nlm:affiliation>Institute for Human Genetics, University of California, San Francisco, San Francisco, California, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Png, Eileen" sort="Png, Eileen" uniqKey="Png E" first="Eileen" last="Png">Eileen Png</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Dunstan, Sarah J" sort="Dunstan, Sarah J" uniqKey="Dunstan S" first="Sarah J" last="Dunstan">Sarah J. Dunstan</name>
<affiliation>
<nlm:affiliation>Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chau, Nguyen Van Vinh" sort="Chau, Nguyen Van Vinh" uniqKey="Chau N" first="Nguyen Van Vinh" last="Chau">Nguyen Van Vinh Chau</name>
<affiliation>
<nlm:affiliation>Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bei, Jinxin" sort="Bei, Jinxin" uniqKey="Bei J" first="Jinxin" last="Bei">Jinxin Bei</name>
<affiliation>
<nlm:affiliation>Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zeng, Yi Xin" sort="Zeng, Yi Xin" uniqKey="Zeng Y" first="Yi Xin" last="Zeng">Yi Xin Zeng</name>
<affiliation>
<nlm:affiliation>Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Karkey, Abhilasha" sort="Karkey, Abhilasha" uniqKey="Karkey A" first="Abhilasha" last="Karkey">Abhilasha Karkey</name>
<affiliation>
<nlm:affiliation>Oxford University Clinical Research Unit-Nepal, Patan Academy of Health Sciences, Patan Hospital, Patan, Nepal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Basnyat, Buddha" sort="Basnyat, Buddha" uniqKey="Basnyat B" first="Buddha" last="Basnyat">Buddha Basnyat</name>
<affiliation>
<nlm:affiliation>Oxford University Clinical Research Unit-Nepal, Patan Academy of Health Sciences, Patan Hospital, Patan, Nepal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pasutto, Francesca" sort="Pasutto, Francesca" uniqKey="Pasutto F" first="Francesca" last="Pasutto">Francesca Pasutto</name>
<affiliation>
<nlm:affiliation>Institute of Human Genetics, Friedrich Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Paoli, Daniela" sort="Paoli, Daniela" uniqKey="Paoli D" first="Daniela" last="Paoli">Daniela Paoli</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Monfalcone Hospital, Gorizia, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Frezzotti, Paolo" sort="Frezzotti, Paolo" uniqKey="Frezzotti P" first="Paolo" last="Frezzotti">Paolo Frezzotti</name>
<affiliation>
<nlm:affiliation>Department of Surgery, Section of Ophthalmology, University of Siena, Siena, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wang, Jie Jin" sort="Wang, Jie Jin" uniqKey="Wang J" first="Jie Jin" last="Wang">Jie Jin Wang</name>
<affiliation>
<nlm:affiliation>Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mitchell, Paul" sort="Mitchell, Paul" uniqKey="Mitchell P" first="Paul" last="Mitchell">Paul Mitchell</name>
<affiliation>
<nlm:affiliation>Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fingert, John H" sort="Fingert, John H" uniqKey="Fingert J" first="John H" last="Fingert">John H. Fingert</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Allingham, R Rand" sort="Allingham, R Rand" uniqKey="Allingham R" first="R Rand" last="Allingham">R Rand Allingham</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hauser, Michael A" sort="Hauser, Michael A" uniqKey="Hauser M" first="Michael A" last="Hauser">Michael A. Hauser</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lim, Soon Thye" sort="Lim, Soon Thye" uniqKey="Lim S" first="Soon Thye" last="Lim">Soon Thye Lim</name>
<affiliation>
<nlm:affiliation>Division of Medical Oncology, National Cancer Centre, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chew, Soo Hong" sort="Chew, Soo Hong" uniqKey="Chew S" first="Soo Hong" last="Chew">Soo Hong Chew</name>
<affiliation>
<nlm:affiliation>Department of Economics, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ebstein, Richard P" sort="Ebstein, Richard P" uniqKey="Ebstein R" first="Richard P" last="Ebstein">Richard P. Ebstein</name>
<affiliation>
<nlm:affiliation>Department of Psychology, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sakuntabhai, Anavaj" sort="Sakuntabhai, Anavaj" uniqKey="Sakuntabhai A" first="Anavaj" last="Sakuntabhai">Anavaj Sakuntabhai</name>
<affiliation>
<nlm:affiliation>Institut Pasteur, Functional Genetics of Infectious Diseases Unit, Department of Genomes and Genetics, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Park, Kyu Hyung" sort="Park, Kyu Hyung" uniqKey="Park K" first="Kyu Hyung" last="Park">Kyu Hyung Park</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggi, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ahn, Jeeyun" sort="Ahn, Jeeyun" uniqKey="Ahn J" first="Jeeyun" last="Ahn">Jeeyun Ahn</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Boland, Greet" sort="Boland, Greet" uniqKey="Boland G" first="Greet" last="Boland">Greet Boland</name>
<affiliation>
<nlm:affiliation>Department of Medical Microbiology and Virology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Snippe, Harm" sort="Snippe, Harm" uniqKey="Snippe H" first="Harm" last="Snippe">Harm Snippe</name>
<affiliation>
<nlm:affiliation>Department of Medical Microbiology and Virology, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Stead, Richard" sort="Stead, Richard" uniqKey="Stead R" first="Richard" last="Stead">Richard Stead</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University Hospital Nottingham, University of Nottingham, Nottingham, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Quino, Raquel" sort="Quino, Raquel" uniqKey="Quino R" first="Raquel" last="Quino">Raquel Quino</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology/Glaucoma Section, Asian Hospital and Medical Center, Muntinlupa City, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zaw, Su Nyunt" sort="Zaw, Su Nyunt" uniqKey="Zaw S" first="Su Nyunt" last="Zaw">Su Nyunt Zaw</name>
<affiliation>
<nlm:affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lukasik, Urszula" sort="Lukasik, Urszula" uniqKey="Lukasik U" first="Urszula" last="Lukasik">Urszula Lukasik</name>
<affiliation>
<nlm:affiliation>Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Shetty, Rohit" sort="Shetty, Rohit" uniqKey="Shetty R" first="Rohit" last="Shetty">Rohit Shetty</name>
<affiliation>
<nlm:affiliation>Narayana Nethralaya Eye Hospital, Bangalore, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zahari, Mimiwati" sort="Zahari, Mimiwati" uniqKey="Zahari M" first="Mimiwati" last="Zahari">Mimiwati Zahari</name>
<affiliation>
<nlm:affiliation>University of Malaya, Eye Research Centre, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bae, Hyoung Won" sort="Bae, Hyoung Won" uniqKey="Bae H" first="Hyoung Won" last="Bae">Hyoung Won Bae</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Oo, Nay Lin" sort="Oo, Nay Lin" uniqKey="Oo N" first="Nay Lin" last="Oo">Nay Lin Oo</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, No. 1 Defence Services General Hospital, Yangon, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kubota, Toshiaki" sort="Kubota, Toshiaki" uniqKey="Kubota T" first="Toshiaki" last="Kubota">Toshiaki Kubota</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Oita University Faculty of Medicine, Oita, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Manassakorn, Anita" sort="Manassakorn, Anita" uniqKey="Manassakorn A" first="Anita" last="Manassakorn">Anita Manassakorn</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ho, Wing Lau" sort="Ho, Wing Lau" uniqKey="Ho W" first="Wing Lau" last="Ho">Wing Lau Ho</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Dallorto, Laura" sort="Dallorto, Laura" uniqKey="Dallorto L" first="Laura" last="Dallorto">Laura Dallorto</name>
<affiliation>
<nlm:affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hwang, Young Hoon" sort="Hwang, Young Hoon" uniqKey="Hwang Y" first="Young Hoon" last="Hwang">Young Hoon Hwang</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kiire, Christine A" sort="Kiire, Christine A" uniqKey="Kiire C" first="Christine A" last="Kiire">Christine A. Kiire</name>
<affiliation>
<nlm:affiliation>Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kuroda, Masako" sort="Kuroda, Masako" uniqKey="Kuroda M" first="Masako" last="Kuroda">Masako Kuroda</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kobe City Medical Center General Hospital, Kobe, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Djamal, Zeiras Eka" sort="Djamal, Zeiras Eka" uniqKey="Djamal Z" first="Zeiras Eka" last="Djamal">Zeiras Eka Djamal</name>
<affiliation>
<nlm:affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Peregrino, Jovell Ian M" sort="Peregrino, Jovell Ian M" uniqKey="Peregrino J" first="Jovell Ian M" last="Peregrino">Jovell Ian M. Peregrino</name>
<affiliation>
<nlm:affiliation>Asian Eye Institute, Manila, Philippines.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ghosh, Arkasubhra" sort="Ghosh, Arkasubhra" uniqKey="Ghosh A" first="Arkasubhra" last="Ghosh">Arkasubhra Ghosh</name>
<affiliation>
<nlm:affiliation>Narayana Nethralaya Eye Hospital, Bangalore, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Jeoung, Jin Wook" sort="Jeoung, Jin Wook" uniqKey="Jeoung J" first="Jin Wook" last="Jeoung">Jin Wook Jeoung</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hoan, Tung S" sort="Hoan, Tung S" uniqKey="Hoan T" first="Tung S" last="Hoan">Tung S. Hoan</name>
<affiliation>
<nlm:affiliation>Eye Department, Viet Tiep General Hospital, Hai Phong, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Srisamran, Nuttamon" sort="Srisamran, Nuttamon" uniqKey="Srisamran N" first="Nuttamon" last="Srisamran">Nuttamon Srisamran</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sandragasu, Thayanithi" sort="Sandragasu, Thayanithi" uniqKey="Sandragasu T" first="Thayanithi" last="Sandragasu">Thayanithi Sandragasu</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Set, Saw Htoo" sort="Set, Saw Htoo" uniqKey="Set S" first="Saw Htoo" last="Set">Saw Htoo Set</name>
<affiliation>
<nlm:affiliation>Mandalay Eye Department, Mandalay Eye ENT Hospital, University of Medicine Mandalay, Mandalay, Myanmar.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Doan, Vi Huyen" sort="Doan, Vi Huyen" uniqKey="Doan V" first="Vi Huyen" last="Doan">Vi Huyen Doan</name>
<affiliation>
<nlm:affiliation>Department of Glaucoma, Da Nang Eye Hospital, Da Nang City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bhattacharya, Shomi S" sort="Bhattacharya, Shomi S" uniqKey="Bhattacharya S" first="Shomi S" last="Bhattacharya">Shomi S. Bhattacharya</name>
<affiliation>
<nlm:affiliation>Division of Genetics, UCL Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ho, Ching Lin" sort="Ho, Ching Lin" uniqKey="Ho C" first="Ching-Lin" last="Ho">Ching-Lin Ho</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tan, Donald T" sort="Tan, Donald T" uniqKey="Tan D" first="Donald T" last="Tan">Donald T. Tan</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sihota, Ramanjit" sort="Sihota, Ramanjit" uniqKey="Sihota R" first="Ramanjit" last="Sihota">Ramanjit Sihota</name>
<affiliation>
<nlm:affiliation>All India Institute of Medical Sciences, New Delhi, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Loon, Seng Chee" sort="Loon, Seng Chee" uniqKey="Loon S" first="Seng-Chee" last="Loon">Seng-Chee Loon</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mori, Kazuhiko" sort="Mori, Kazuhiko" uniqKey="Mori K" first="Kazuhiko" last="Mori">Kazuhiko Mori</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kinoshita, Shigeru" sort="Kinoshita, Shigeru" uniqKey="Kinoshita S" first="Shigeru" last="Kinoshita">Shigeru Kinoshita</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hollander, Anneke I Den" sort="Hollander, Anneke I Den" uniqKey="Hollander A" first="Anneke I Den" last="Hollander">Anneke I Den Hollander</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Qamar, Raheel" sort="Qamar, Raheel" uniqKey="Qamar R" first="Raheel" last="Qamar">Raheel Qamar</name>
<affiliation>
<nlm:affiliation>Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wang, Ya Xing" sort="Wang, Ya Xing" uniqKey="Wang Y" first="Ya-Xing" last="Wang">Ya-Xing Wang</name>
<affiliation>
<nlm:affiliation>Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Teo, Yik Y" sort="Teo, Yik Y" uniqKey="Teo Y" first="Yik Y" last="Teo">Yik Y. Teo</name>
<affiliation>
<nlm:affiliation>Genome Institute of Singapore, A-STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tai, E Shyong" sort="Tai, E Shyong" uniqKey="Tai E" first="E-Shyong" last="Tai">E-Shyong Tai</name>
<affiliation>
<nlm:affiliation>Saw Swee Hock School of Public Health, National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hartleben Matkin, Curt" sort="Hartleben Matkin, Curt" uniqKey="Hartleben Matkin C" first="Curt" last="Hartleben-Matkin">Curt Hartleben-Matkin</name>
<affiliation>
<nlm:affiliation>Department of Glaucoma, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lozano Giral, David" sort="Lozano Giral, David" uniqKey="Lozano Giral D" first="David" last="Lozano-Giral">David Lozano-Giral</name>
<affiliation>
<nlm:affiliation>Department of Genetics, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Saw, Seang Mei" sort="Saw, Seang Mei" uniqKey="Saw S" first="Seang Mei" last="Saw">Seang Mei Saw</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cheng, Ching Yu" sort="Cheng, Ching Yu" uniqKey="Cheng C" first="Ching-Yu" last="Cheng">Ching-Yu Cheng</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zenteno, Juan C" sort="Zenteno, Juan C" uniqKey="Zenteno J" first="Juan C" last="Zenteno">Juan C. Zenteno</name>
<affiliation>
<nlm:affiliation>Department of Genetics, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pang, Chi Pui" sort="Pang, Chi Pui" uniqKey="Pang C" first="Chi Pui" last="Pang">Chi Pui Pang</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bui, Huong T T" sort="Bui, Huong T T" uniqKey="Bui H" first="Huong T T" last="Bui">Huong T T. Bui</name>
<affiliation>
<nlm:affiliation>Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hee, Owen" sort="Hee, Owen" uniqKey="Hee O" first="Owen" last="Hee">Owen Hee</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Craig, Jamie E" sort="Craig, Jamie E" uniqKey="Craig J" first="Jamie E" last="Craig">Jamie E. Craig</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Edward, Deepak P" sort="Edward, Deepak P" uniqKey="Edward D" first="Deepak P" last="Edward">Deepak P. Edward</name>
<affiliation>
<nlm:affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Yonahara, Michiko" sort="Yonahara, Michiko" uniqKey="Yonahara M" first="Michiko" last="Yonahara">Michiko Yonahara</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, University of the Ryukyus, Okinawa, Nishihara, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Neto, Jamil Miguel" sort="Neto, Jamil Miguel" uniqKey="Neto J" first="Jamil Miguel" last="Neto">Jamil Miguel Neto</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Guevara Fujita, Maria L" sort="Guevara Fujita, Maria L" uniqKey="Guevara Fujita M" first="Maria L" last="Guevara-Fujita">Maria L. Guevara-Fujita</name>
<affiliation>
<nlm:affiliation>Centro de Genética y Biología Molecular, Universidad de San Martín de Porres, Lima, Peru.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Xu, Liang" sort="Xu, Liang" uniqKey="Xu L" first="Liang" last="Xu">Liang Xu</name>
<affiliation>
<nlm:affiliation>Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ritch, Robert" sort="Ritch, Robert" uniqKey="Ritch R" first="Robert" last="Ritch">Robert Ritch</name>
<affiliation>
<nlm:affiliation>Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liza Sharmini, Ahmad Tajudin" sort="Liza Sharmini, Ahmad Tajudin" uniqKey="Liza Sharmini A" first="Ahmad Tajudin" last="Liza-Sharmini">Ahmad Tajudin Liza-Sharmini</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia and Hospital Universiti Sains Malaysia, Kelantan, Malaysia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wong, Tien Y" sort="Wong, Tien Y" uniqKey="Wong T" first="Tien Y" last="Wong">Tien Y. Wong</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Al Obeidan, Saleh" sort="Al Obeidan, Saleh" uniqKey="Al Obeidan S" first="Saleh" last="Al-Obeidan">Saleh Al-Obeidan</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Do, Nhu Hon" sort="Do, Nhu Hon" uniqKey="Do N" first="Nhu Hon" last="Do">Nhu Hon Do</name>
<affiliation>
<nlm:affiliation>Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sundaresan, Periasamy" sort="Sundaresan, Periasamy" uniqKey="Sundaresan P" first="Periasamy" last="Sundaresan">Periasamy Sundaresan</name>
<affiliation>
<nlm:affiliation>Department of Genetics, Aravind Medical Research Foundation, Madurai, India.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tham, Clement C" sort="Tham, Clement C" uniqKey="Tham C" first="Clement C" last="Tham">Clement C. Tham</name>
<affiliation>
<nlm:affiliation>Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Foster, Paul J" sort="Foster, Paul J" uniqKey="Foster P" first="Paul J" last="Foster">Paul J. Foster</name>
<affiliation>
<nlm:affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vijaya, Lingam" sort="Vijaya, Lingam" uniqKey="Vijaya L" first="Lingam" last="Vijaya">Lingam Vijaya</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tashiro, Kei" sort="Tashiro, Kei" uniqKey="Tashiro K" first="Kei" last="Tashiro">Kei Tashiro</name>
<affiliation>
<nlm:affiliation>Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vithana, Eranga N" sort="Vithana, Eranga N" uniqKey="Vithana E" first="Eranga N" last="Vithana">Eranga N. Vithana</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wang, Ningli" sort="Wang, Ningli" uniqKey="Wang N" first="Ningli" last="Wang">Ningli Wang</name>
<affiliation>
<nlm:affiliation>Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Aung, Tin" sort="Aung, Tin" uniqKey="Aung T" first="Tin" last="Aung">Tin Aung</name>
<affiliation>
<nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Nature genetics</title>
<idno type="eISSN">1546-1718</idno>
<imprint>
<date when="2016" type="published">2016</date>
</imprint>
</series>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Cell Line</term>
<term>Chromosome Mapping</term>
<term>Female</term>
<term>Gene Expression</term>
<term>Genetic Loci</term>
<term>Genetic Predisposition to Disease</term>
<term>Genome-Wide Association Study</term>
<term>Genotype</term>
<term>Glaucoma, Angle-Closure (genetics)</term>
<term>Humans</term>
<term>Male</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en">
<term>Glaucoma, Angle-Closure</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Cell Line</term>
<term>Chromosome Mapping</term>
<term>Female</term>
<term>Gene Expression</term>
<term>Genetic Loci</term>
<term>Genetic Predisposition to Disease</term>
<term>Genome-Wide Association Study</term>
<term>Genotype</term>
<term>Humans</term>
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<front>
<div type="abstract" xml:lang="en">Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We conducted a genome-wide association study (GWAS) followed by replication in a combined total of 10,503 PACG cases and 29,567 controls drawn from 24 countries across Asia, Australia, Europe, North America, and South America. We observed significant evidence of disease association at five new genetic loci upon meta-analysis of all patient collections. These loci are at EPDR1 rs3816415 (odds ratio (OR) = 1.24, P = 5.94 × 10(-15)), CHAT rs1258267 (OR = 1.22, P = 2.85 × 10(-16)), GLIS3 rs736893 (OR = 1.18, P = 1.43 × 10(-14)), FERMT2 rs7494379 (OR = 1.14, P = 3.43 × 10(-11)), and DPM2-FAM102A rs3739821 (OR = 1.15, P = 8.32 × 10(-12)). We also confirmed significant association at three previously described loci (P < 5 × 10(-8) for each sentinel SNP at PLEKHA7, COL11A1, and PCMTD1-ST18), providing new insights into the biology of PACG.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">27064256</PMID>
<DateCreated>
<Year>2016</Year>
<Month>04</Month>
<Day>28</Day>
</DateCreated>
<DateCompleted>
<Year>2017</Year>
<Month>05</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised>
<Year>2017</Year>
<Month>09</Month>
<Day>22</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1546-1718</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>48</Volume>
<Issue>5</Issue>
<PubDate>
<Year>2016</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Nature genetics</Title>
<ISOAbbreviation>Nat. Genet.</ISOAbbreviation>
</Journal>
<ArticleTitle>Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.</ArticleTitle>
<Pagination>
<MedlinePgn>556-62</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/ng.3540</ELocationID>
<Abstract>
<AbstractText>Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We conducted a genome-wide association study (GWAS) followed by replication in a combined total of 10,503 PACG cases and 29,567 controls drawn from 24 countries across Asia, Australia, Europe, North America, and South America. We observed significant evidence of disease association at five new genetic loci upon meta-analysis of all patient collections. These loci are at EPDR1 rs3816415 (odds ratio (OR) = 1.24, P = 5.94 × 10(-15)), CHAT rs1258267 (OR = 1.22, P = 2.85 × 10(-16)), GLIS3 rs736893 (OR = 1.18, P = 1.43 × 10(-14)), FERMT2 rs7494379 (OR = 1.14, P = 3.43 × 10(-11)), and DPM2-FAM102A rs3739821 (OR = 1.15, P = 8.32 × 10(-12)). We also confirmed significant association at three previously described loci (P < 5 × 10(-8) for each sentinel SNP at PLEKHA7, COL11A1, and PCMTD1-ST18), providing new insights into the biology of PACG.</AbstractText>
</Abstract>
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<Author ValidYN="Y">
<LastName>Khor</LastName>
<ForeName>Chiea Chuen</ForeName>
<Initials>CC</Initials>
<AffiliationInfo>
<Affiliation>Genome Institute of Singapore, A-STAR, Singapore.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Biochemistry, National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Do</LastName>
<ForeName>Tan</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Jia</LastName>
<ForeName>Hongyan</ForeName>
<Initials>H</Initials>
<AffiliationInfo>
<Affiliation>Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Nakano</LastName>
<ForeName>Masakazu</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>George</LastName>
<ForeName>Ronnie</ForeName>
<Initials>R</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0001-7368-0252</Identifier>
<AffiliationInfo>
<Affiliation>Jadhavbhai Nathamal Singhvi Department of Glaucoma, Medical Research Foundation, Sankara Nethralaya, Chennai, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Abu-Amero</LastName>
<ForeName>Khaled</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, College of Medicine, University of Florida, Jacksonville, Florida, USA.</Affiliation>
</AffiliationInfo>
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<LastName>Duvesh</LastName>
<ForeName>Roopam</ForeName>
<Initials>R</Initials>
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<Affiliation>Department of Genetics, Aravind Medical Research Foundation, Madurai, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Chen</LastName>
<ForeName>Li Jia</ForeName>
<Initials>LJ</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Li</LastName>
<ForeName>Zheng</ForeName>
<Initials>Z</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0002-7060-2213</Identifier>
<AffiliationInfo>
<Affiliation>Genome Institute of Singapore, A-STAR, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Nongpiur</LastName>
<ForeName>Monisha E</ForeName>
<Initials>ME</Initials>
<AffiliationInfo>
<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Perera</LastName>
<ForeName>Shamira A</ForeName>
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<AffiliationInfo>
<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
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<LastName>Qiao</LastName>
<ForeName>Chunyan</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wong</LastName>
<ForeName>Hon-Tym</ForeName>
<Initials>HT</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sakai</LastName>
<ForeName>Hiroshi</ForeName>
<Initials>H</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, University of the Ryukyus, Okinawa, Nishihara, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Barbosa de Melo</LastName>
<ForeName>Mônica</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Center of Molecular Biology and Genetic Engineering, University of Campinas, Campinas, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Lee</LastName>
<ForeName>Mei-Chin</ForeName>
<Initials>MC</Initials>
<AffiliationInfo>
<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Chan</LastName>
<ForeName>Anita S</ForeName>
<Initials>AS</Initials>
<AffiliationInfo>
<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Azhany</LastName>
<ForeName>Yaakub</ForeName>
<Initials>Y</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia and Hospital Universiti Sains Malaysia, Kelantan, Malaysia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Dao</LastName>
<ForeName>Thi Lam Huong</ForeName>
<Initials>TL</Initials>
<AffiliationInfo>
<Affiliation>Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ikeda</LastName>
<ForeName>Yoko</ForeName>
<Initials>Y</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Perez-Grossmann</LastName>
<ForeName>Rodolfo A</ForeName>
<Initials>RA</Initials>
<AffiliationInfo>
<Affiliation>Instituto de Glaucoma y Catarata, Lima, Peru.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Zarnowski</LastName>
<ForeName>Tomasz</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Day</LastName>
<ForeName>Alexander C</ForeName>
<Initials>AC</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0002-2099-8870</Identifier>
<AffiliationInfo>
<Affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Glaucoma Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Division of Genetics, UCL Institute of Ophthalmology, London, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Jonas</LastName>
<ForeName>Jost B</ForeName>
<Initials>JB</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht Karls University Heidelberg, Heidelberg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Tam</LastName>
<ForeName>Pancy O S</ForeName>
<Initials>PO</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Tran</LastName>
<ForeName>Tuan Anh</ForeName>
<Initials>TA</Initials>
<AffiliationInfo>
<Affiliation>Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ayub</LastName>
<ForeName>Humaira</ForeName>
<Initials>H</Initials>
<AffiliationInfo>
<Affiliation>Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Akhtar</LastName>
<ForeName>Farah</ForeName>
<Initials>F</Initials>
<AffiliationInfo>
<Affiliation>Pakistan Institute of Ophthalmology, Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Micheal</LastName>
<ForeName>Shazia</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Chew</LastName>
<ForeName>Paul T K</ForeName>
<Initials>PT</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Aljasim</LastName>
<ForeName>Leyla A</ForeName>
<Initials>LA</Initials>
<AffiliationInfo>
<Affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Dada</LastName>
<ForeName>Tanuj</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>All India Institute of Medical Sciences, New Delhi, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Luu</LastName>
<ForeName>Tam Thi</ForeName>
<Initials>TT</Initials>
<AffiliationInfo>
<Affiliation>Department of Glaucoma, Da Nang Eye Hospital, Da Nang City, Vietnam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Awadalla</LastName>
<ForeName>Mona S</ForeName>
<Initials>MS</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Kitnarong</LastName>
<ForeName>Naris</ForeName>
<Initials>N</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wanichwecharungruang</LastName>
<ForeName>Boonsong</ForeName>
<Initials>B</Initials>
<AffiliationInfo>
<Affiliation>Glaucoma Services, Department of Ophthalmology, Rajavithi Hospital, Bangkok, Thailand.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>College of Medicine, Rangsit University, Bangkok, Thailand.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Aung</LastName>
<ForeName>Yee Yee</ForeName>
<Initials>YY</Initials>
<AffiliationInfo>
<Affiliation>Mandalay Eye Department, Mandalay Eye ENT Hospital, University of Medicine Mandalay, Mandalay, Myanmar.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Mohamed-Noor</LastName>
<ForeName>Jelinar</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.</Affiliation>
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<Affiliation>Division of Ophthalmology, Changi General Hospital, Singapore.</Affiliation>
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<Affiliation>Division of Ophthalmology, University of the East, Manila, Philippines.</Affiliation>
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<Affiliation>Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.</Affiliation>
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<Affiliation>Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Republic of Korea.</Affiliation>
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<Affiliation>Ozaki Eye Hospital, Hyuga, Japan.</Affiliation>
</AffiliationInfo>
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<Affiliation>Department of Ophthalmology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.</Affiliation>
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<ForeName>Visanee</ForeName>
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<Affiliation>Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.</Affiliation>
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<ForeName>Chaw Chaw</ForeName>
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<Affiliation>Department of Ophthalmology, No. 1 Defence Services General Hospital, Yangon, Myanmar.</Affiliation>
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<ForeName>Takanori</ForeName>
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<ForeName>Satoko</ForeName>
<Initials>S</Initials>
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<Affiliation>Department of Ophthalmology, Oita University Faculty of Medicine, Oita, Japan.</Affiliation>
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<ForeName>Chan-Yun</ForeName>
<Initials>CY</Initials>
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<Affiliation>Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.</Affiliation>
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<ForeName>Sujie</ForeName>
<Initials>S</Initials>
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<Initials>R</Initials>
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<ForeName>Morio</ForeName>
<Initials>M</Initials>
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<Affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</Affiliation>
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<Initials>N</Initials>
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<Affiliation>Myanmar Eye Centre, Shwe La Min Hospital, Yangon, Myanmar.</Affiliation>
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<Affiliation>Binan Doctors Eye Center, Binan Doctors Hospital, Laguna, Philippines.</Affiliation>
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<Affiliation>Department of Ophthalmology, University Hospital Nottingham, University of Nottingham, Nottingham, UK.</Affiliation>
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<Affiliation>BMI Park Hospital Nottingham, Nottingham, UK.</Affiliation>
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<Affiliation>Genome Institute of Singapore, A-STAR, Singapore.</Affiliation>
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<ForeName>Tina T</ForeName>
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<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
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<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
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<ForeName>Rengaraj</ForeName>
<Initials>R</Initials>
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<Affiliation>Glaucoma Clinic, Aravind Eye Hospital, Pondicherry, India.</Affiliation>
</AffiliationInfo>
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<ForeName>Srinivasan</ForeName>
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<Affiliation>Glaucoma Clinic, Aravind Eye Hospital, Pondicherry, India.</Affiliation>
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<ForeName>Subbiah R</ForeName>
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<Affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</Affiliation>
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<ForeName>Nagaswamy</ForeName>
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<ForeName>Balekudaru</ForeName>
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<Affiliation>Jadhavbhai Nathamal Singhvi Department of Glaucoma, Medical Research Foundation, Sankara Nethralaya, Chennai, India.</Affiliation>
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<ForeName>Boon-Ang</ForeName>
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<Affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</Affiliation>
</AffiliationInfo>
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<ForeName>Jeanne</ForeName>
<Initials>J</Initials>
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<Affiliation>Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.</Affiliation>
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<ForeName>José P C</ForeName>
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<Affiliation>Department of Ophthalmology, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.</Affiliation>
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<LastName>Costa</LastName>
<ForeName>Vital P</ForeName>
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<Affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</Affiliation>
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<Affiliation>Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.</Affiliation>
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<ForeName>Bruno B</ForeName>
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<ForeName>Chelvin C</ForeName>
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<Affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
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<Affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
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<Initials>E</Initials>
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<Affiliation>Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.</Affiliation>
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</Author>
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<LastName>Fong</LastName>
<ForeName>Guillermo Barreto</ForeName>
<Initials>GB</Initials>
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<ForeName>Vania Castro</ForeName>
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<Initials>R</Initials>
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<ForeName>Yuzhen</ForeName>
<Initials>Y</Initials>
<AffiliationInfo>
<Affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Glaucoma Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Division of Genetics, UCL Institute of Ophthalmology, London, UK.</Affiliation>
</AffiliationInfo>
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<LastName>Waseem</LastName>
<ForeName>Naushin</ForeName>
<Initials>N</Initials>
<AffiliationInfo>
<Affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Division of Genetics, UCL Institute of Ophthalmology, London, UK.</Affiliation>
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<ForeName>Sancy</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Glaucoma Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Division of Genetics, UCL Institute of Ophthalmology, London, UK.</Affiliation>
</AffiliationInfo>
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<LastName>Pham</LastName>
<ForeName>Huan Nguyen</ForeName>
<Initials>HN</Initials>
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<ForeName>Sami</ForeName>
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<Affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</Affiliation>
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<LastName>Craven</LastName>
<ForeName>E Randy</ForeName>
<Initials>ER</Initials>
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<Affiliation>King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.</Affiliation>
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<AffiliationInfo>
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</AffiliationInfo>
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<LastName>Dada</LastName>
<ForeName>Rrima</ForeName>
<Initials>R</Initials>
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</AffiliationInfo>
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<AffiliationInfo>
<Affiliation>Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.</Affiliation>
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<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.</Affiliation>
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<AffiliationInfo>
<Affiliation>Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.</Affiliation>
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<ForeName>Eng Hui</ForeName>
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<Affiliation>Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.</Affiliation>
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<ForeName>Anuwat</ForeName>
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<ForeName>Lerprat</ForeName>
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<ForeName>Bonnie N K</ForeName>
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<ForeName>Jennifer W H</ForeName>
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<ForeName>Hlaing May</ForeName>
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<ForeName>Khin Thida</ForeName>
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<Affiliation>Myanmar Eye Centre, Shwe La Min Hospital, Yangon, Myanmar.</Affiliation>
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<ForeName>Shuang Ru</ForeName>
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<ForeName>Yaan Fun</ForeName>
<Initials>YF</Initials>
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<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
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<Affiliation>Genome Institute of Singapore, A-STAR, Singapore.</Affiliation>
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<ForeName>Mark</ForeName>
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<Affiliation>Institute for Human Genetics, University of California, San Francisco, San Francisco, California, USA.</Affiliation>
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<ForeName>Eileen</ForeName>
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<Affiliation>Genome Institute of Singapore, A-STAR, Singapore.</Affiliation>
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<ForeName>Sarah J</ForeName>
<Initials>SJ</Initials>
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<Affiliation>Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.</Affiliation>
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<AffiliationInfo>
<Affiliation>Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.</Affiliation>
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<LastName>Chau</LastName>
<ForeName>Nguyen Van Vinh</ForeName>
<Initials>NV</Initials>
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<ForeName>Jinxin</ForeName>
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<Affiliation>Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</Affiliation>
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<AffiliationInfo>
<Affiliation>Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, China.</Affiliation>
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<LastName>Zeng</LastName>
<ForeName>Yi Xin</ForeName>
<Initials>YX</Initials>
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<Affiliation>Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</Affiliation>
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<AffiliationInfo>
<Affiliation>Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Peking Union Medical College, Beijing, China.</Affiliation>
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<LastName>Karkey</LastName>
<ForeName>Abhilasha</ForeName>
<Initials>A</Initials>
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<Affiliation>Oxford University Clinical Research Unit-Nepal, Patan Academy of Health Sciences, Patan Hospital, Patan, Nepal.</Affiliation>
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<LastName>Basnyat</LastName>
<ForeName>Buddha</ForeName>
<Initials>B</Initials>
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<Affiliation>Oxford University Clinical Research Unit-Nepal, Patan Academy of Health Sciences, Patan Hospital, Patan, Nepal.</Affiliation>
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<LastName>Pasutto</LastName>
<ForeName>Francesca</ForeName>
<Initials>F</Initials>
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<Affiliation>Institute of Human Genetics, Friedrich Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.</Affiliation>
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<Author ValidYN="Y">
<LastName>Paoli</LastName>
<ForeName>Daniela</ForeName>
<Initials>D</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Monfalcone Hospital, Gorizia, Italy.</Affiliation>
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</Author>
<Author ValidYN="Y">
<LastName>Frezzotti</LastName>
<ForeName>Paolo</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Department of Surgery, Section of Ophthalmology, University of Siena, Siena, Italy.</Affiliation>
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<Author ValidYN="Y">
<LastName>Wang</LastName>
<ForeName>Jie Jin</ForeName>
<Initials>JJ</Initials>
<AffiliationInfo>
<Affiliation>Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.</Affiliation>
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<Author ValidYN="Y">
<LastName>Mitchell</LastName>
<ForeName>Paul</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.</Affiliation>
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</Author>
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<LastName>Fingert</LastName>
<ForeName>John H</ForeName>
<Initials>JH</Initials>
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<Affiliation>Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.</Affiliation>
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<AffiliationInfo>
<Affiliation>Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa, USA.</Affiliation>
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<Author ValidYN="Y">
<LastName>Allingham</LastName>
<ForeName>R Rand</ForeName>
<Initials>RR</Initials>
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<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina, USA.</Affiliation>
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<Author ValidYN="Y">
<LastName>Hauser</LastName>
<ForeName>Michael A</ForeName>
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<Identifier Source="ORCID">http://orcid.org/0000-0003-2667-5420</Identifier>
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<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina, USA.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.</Affiliation>
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</Author>
<Author ValidYN="Y">
<LastName>Lim</LastName>
<ForeName>Soon Thye</ForeName>
<Initials>ST</Initials>
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<Affiliation>Division of Medical Oncology, National Cancer Centre, Singapore.</Affiliation>
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<LastName>Chew</LastName>
<ForeName>Soo Hong</ForeName>
<Initials>SH</Initials>
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<Affiliation>Department of Economics, National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
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<LastName>Ebstein</LastName>
<ForeName>Richard P</ForeName>
<Initials>RP</Initials>
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<Affiliation>Department of Psychology, National University of Singapore, Singapore.</Affiliation>
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<LastName>Sakuntabhai</LastName>
<ForeName>Anavaj</ForeName>
<Initials>A</Initials>
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<Affiliation>Institut Pasteur, Functional Genetics of Infectious Diseases Unit, Department of Genomes and Genetics, Paris, France.</Affiliation>
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<AffiliationInfo>
<Affiliation>Centre National de la Recherche Scientifique, Unité de Recherche Associée 3012, Paris, France.</Affiliation>
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<Author ValidYN="Y">
<LastName>Park</LastName>
<ForeName>Kyu Hyung</ForeName>
<Initials>KH</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggi, Republic of Korea.</Affiliation>
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</Author>
<Author ValidYN="Y">
<LastName>Ahn</LastName>
<ForeName>Jeeyun</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Boland</LastName>
<ForeName>Greet</ForeName>
<Initials>G</Initials>
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<Affiliation>Department of Medical Microbiology and Virology, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation>
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</Author>
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<LastName>Snippe</LastName>
<ForeName>Harm</ForeName>
<Initials>H</Initials>
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<Affiliation>Department of Medical Microbiology and Virology, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation>
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<LastName>Stead</LastName>
<ForeName>Richard</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, University Hospital Nottingham, University of Nottingham, Nottingham, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Quino</LastName>
<ForeName>Raquel</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology/Glaucoma Section, Asian Hospital and Medical Center, Muntinlupa City, Philippines.</Affiliation>
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<LastName>Zaw</LastName>
<ForeName>Su Nyunt</ForeName>
<Initials>SN</Initials>
<AffiliationInfo>
<Affiliation>Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Myanmar Eye Centre, Shwe La Min Hospital, Yangon, Myanmar.</Affiliation>
</AffiliationInfo>
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<LastName>Lukasik</LastName>
<ForeName>Urszula</ForeName>
<Initials>U</Initials>
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<Affiliation>Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Shetty</LastName>
<ForeName>Rohit</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Narayana Nethralaya Eye Hospital, Bangalore, India.</Affiliation>
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<LastName>Zahari</LastName>
<ForeName>Mimiwati</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>University of Malaya, Eye Research Centre, Kuala Lumpur, Malaysia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.</Affiliation>
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<LastName>Bae</LastName>
<ForeName>Hyoung Won</ForeName>
<Initials>HW</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y">
<LastName>Oo</LastName>
<ForeName>Nay Lin</ForeName>
<Initials>NL</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, No. 1 Defence Services General Hospital, Yangon, Myanmar.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Kubota</LastName>
<ForeName>Toshiaki</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Oita University Faculty of Medicine, Oita, Japan.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Manassakorn</LastName>
<ForeName>Anita</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ho</LastName>
<ForeName>Wing Lau</ForeName>
<Initials>WL</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.</Affiliation>
</AffiliationInfo>
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<LastName>Dallorto</LastName>
<ForeName>Laura</ForeName>
<Initials>L</Initials>
<AffiliationInfo>
<Affiliation>Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Hwang</LastName>
<ForeName>Young Hoon</ForeName>
<Initials>YH</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Kiire</LastName>
<ForeName>Christine A</ForeName>
<Initials>CA</Initials>
<AffiliationInfo>
<Affiliation>Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.</Affiliation>
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</Author>
<Author ValidYN="Y">
<LastName>Kuroda</LastName>
<ForeName>Masako</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Kobe City Medical Center General Hospital, Kobe, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Djamal</LastName>
<ForeName>Zeiras Eka</ForeName>
<Initials>ZE</Initials>
<AffiliationInfo>
<Affiliation>Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Peregrino</LastName>
<ForeName>Jovell Ian M</ForeName>
<Initials>JI</Initials>
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<Affiliation>Asian Eye Institute, Manila, Philippines.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ghosh</LastName>
<ForeName>Arkasubhra</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Narayana Nethralaya Eye Hospital, Bangalore, India.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>GROW Research Laboratory, Narayana Nethralaya Foundation, Bangalore, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Jeoung</LastName>
<ForeName>Jin Wook</ForeName>
<Initials>JW</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Hoan</LastName>
<ForeName>Tung S</ForeName>
<Initials>TS</Initials>
<AffiliationInfo>
<Affiliation>Eye Department, Viet Tiep General Hospital, Hai Phong, Vietnam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Srisamran</LastName>
<ForeName>Nuttamon</ForeName>
<Initials>N</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sandragasu</LastName>
<ForeName>Thayanithi</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y">
<LastName>Set</LastName>
<ForeName>Saw Htoo</ForeName>
<Initials>SH</Initials>
<AffiliationInfo>
<Affiliation>Mandalay Eye Department, Mandalay Eye ENT Hospital, University of Medicine Mandalay, Mandalay, Myanmar.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Doan</LastName>
<ForeName>Vi Huyen</ForeName>
<Initials>VH</Initials>
<AffiliationInfo>
<Affiliation>Department of Glaucoma, Da Nang Eye Hospital, Da Nang City, Vietnam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Bhattacharya</LastName>
<ForeName>Shomi S</ForeName>
<Initials>SS</Initials>
<AffiliationInfo>
<Affiliation>Division of Genetics, UCL Institute of Ophthalmology, London, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ho</LastName>
<ForeName>Ching-Lin</ForeName>
<Initials>CL</Initials>
<AffiliationInfo>
<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Tan</LastName>
<ForeName>Donald T</ForeName>
<Initials>DT</Initials>
<AffiliationInfo>
<Affiliation>Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y">
<LastName>Sihota</LastName>
<ForeName>Ramanjit</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>All India Institute of Medical Sciences, New Delhi, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Loon</LastName>
<ForeName>Seng-Chee</ForeName>
<Initials>SC</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Mori</LastName>
<ForeName>Kazuhiko</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Kinoshita</LastName>
<ForeName>Shigeru</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.</Affiliation>
</AffiliationInfo>
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