Bioabsorbable Intracoronary Matrix for Prevention of Ventricular Remodeling After Myocardial Infarction.
Identifieur interne : 001A99 ( PubMed/Corpus ); précédent : 001A98; suivant : 001B00Bioabsorbable Intracoronary Matrix for Prevention of Ventricular Remodeling After Myocardial Infarction.
Auteurs : Sunil V. Rao ; Uwe Zeymer ; Pamela S. Douglas ; Hussein Al-Khalidi ; Jennifer A. White ; Jingyu Liu ; Howard Levy ; Victor Guetta ; C Michael Gibson ; Jean-Francois Tanguay ; Paul Vermeersch ; Jérôme Roncalli ; Jaroslaw D. Kasprzak ; Timothy D. Henry ; Norbert Frey ; Oscar Kracoff ; Jay H. Traverse ; Derek P. Chew ; Jose Lopez-Sendon ; Reinilde Heyrman ; Mitchell W. KrucoffSource :
- Journal of the American College of Cardiology [ 1558-3597 ] ; 2016.
English descriptors
- KwdEn :
- Absorbable Implants, Aged, Coronary Angiography, Coronary Vessels (diagnostic imaging), Coronary Vessels (surgery), Double-Blind Method, Electrocardiography, Female, Follow-Up Studies, Heart Ventricles (diagnostic imaging), Heart Ventricles (physiopathology), Humans, Male, Middle Aged, Myocardial Infarction (diagnosis), Myocardial Infarction (physiopathology), Myocardial Infarction (surgery), Percutaneous Coronary Intervention, Postoperative Complications (prevention & control), Prosthesis Design, Stents, Treatment Outcome, Ventricular Function, Left (physiology), Ventricular Remodeling.
- MESH :
- diagnosis : Myocardial Infarction.
- diagnostic imaging : Coronary Vessels, Heart Ventricles.
- physiology : Ventricular Function, Left.
- physiopathology : Heart Ventricles, Myocardial Infarction.
- prevention & control : Postoperative Complications.
- surgery : Coronary Vessels, Myocardial Infarction.
- Absorbable Implants, Aged, Coronary Angiography, Double-Blind Method, Electrocardiography, Female, Follow-Up Studies, Humans, Male, Middle Aged, Percutaneous Coronary Intervention, Prosthesis Design, Stents, Treatment Outcome, Ventricular Remodeling.
Abstract
Bioabsorbable cardiac matrix (BCM) is a novel device that attenuates adverse left ventricular (LV) remodeling after large myocardial infarctions in experimental models.
DOI: 10.1016/j.jacc.2016.05.053
PubMed: 27515331
Links to Exploration step
pubmed:27515331Le document en format XML
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<author><name sortKey="Zeymer, Uwe" sort="Zeymer, Uwe" uniqKey="Zeymer U" first="Uwe" last="Zeymer">Uwe Zeymer</name>
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</affiliation>
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<author><name sortKey="Al Khalidi, Hussein" sort="Al Khalidi, Hussein" uniqKey="Al Khalidi H" first="Hussein" last="Al-Khalidi">Hussein Al-Khalidi</name>
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<author><name sortKey="Liu, Jingyu" sort="Liu, Jingyu" uniqKey="Liu J" first="Jingyu" last="Liu">Jingyu Liu</name>
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<author><name sortKey="Levy, Howard" sort="Levy, Howard" uniqKey="Levy H" first="Howard" last="Levy">Howard Levy</name>
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<author><name sortKey="Gibson, C Michael" sort="Gibson, C Michael" uniqKey="Gibson C" first="C Michael" last="Gibson">C Michael Gibson</name>
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<author><name sortKey="Tanguay, Jean Francois" sort="Tanguay, Jean Francois" uniqKey="Tanguay J" first="Jean-Francois" last="Tanguay">Jean-Francois Tanguay</name>
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<author><name sortKey="Vermeersch, Paul" sort="Vermeersch, Paul" uniqKey="Vermeersch P" first="Paul" last="Vermeersch">Paul Vermeersch</name>
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</affiliation>
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<author><name sortKey="Roncalli, Jerome" sort="Roncalli, Jerome" uniqKey="Roncalli J" first="Jérôme" last="Roncalli">Jérôme Roncalli</name>
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</affiliation>
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<author><name sortKey="Kasprzak, Jaroslaw D" sort="Kasprzak, Jaroslaw D" uniqKey="Kasprzak J" first="Jaroslaw D" last="Kasprzak">Jaroslaw D. Kasprzak</name>
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</affiliation>
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<author><name sortKey="Henry, Timothy D" sort="Henry, Timothy D" uniqKey="Henry T" first="Timothy D" last="Henry">Timothy D. Henry</name>
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</affiliation>
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<author><name sortKey="Frey, Norbert" sort="Frey, Norbert" uniqKey="Frey N" first="Norbert" last="Frey">Norbert Frey</name>
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</affiliation>
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<author><name sortKey="Kracoff, Oscar" sort="Kracoff, Oscar" uniqKey="Kracoff O" first="Oscar" last="Kracoff">Oscar Kracoff</name>
<affiliation><nlm:affiliation>Kaplan Medical Center, Rehovot, Israel.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Traverse, Jay H" sort="Traverse, Jay H" uniqKey="Traverse J" first="Jay H" last="Traverse">Jay H. Traverse</name>
<affiliation><nlm:affiliation>Minneapolis Heart Institute, Minneapolis, Minnesota.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chew, Derek P" sort="Chew, Derek P" uniqKey="Chew D" first="Derek P" last="Chew">Derek P. Chew</name>
<affiliation><nlm:affiliation>Flinders University, Adelaide, South Australia, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lopez Sendon, Jose" sort="Lopez Sendon, Jose" uniqKey="Lopez Sendon J" first="Jose" last="Lopez-Sendon">Jose Lopez-Sendon</name>
<affiliation><nlm:affiliation>Hospital Universitario La Paz, Madrid, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Heyrman, Reinilde" sort="Heyrman, Reinilde" uniqKey="Heyrman R" first="Reinilde" last="Heyrman">Reinilde Heyrman</name>
<affiliation><nlm:affiliation>Bellerophon Therapeutics Inc., Hampton, New Jersey.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Krucoff, Mitchell W" sort="Krucoff, Mitchell W" uniqKey="Krucoff M" first="Mitchell W" last="Krucoff">Mitchell W. Krucoff</name>
<affiliation><nlm:affiliation>Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Bioabsorbable Intracoronary Matrix for Prevention of Ventricular Remodeling After Myocardial Infarction.</title>
<author><name sortKey="Rao, Sunil V" sort="Rao, Sunil V" uniqKey="Rao S" first="Sunil V" last="Rao">Sunil V. Rao</name>
<affiliation><nlm:affiliation>Duke Clinical Research Institute, Durham, North Carolina. Electronic address: sunil.rao@duke.edu.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Zeymer, Uwe" sort="Zeymer, Uwe" uniqKey="Zeymer U" first="Uwe" last="Zeymer">Uwe Zeymer</name>
<affiliation><nlm:affiliation>Herzzentrum Luwidshafen, Ludwigshafen, Germany.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Douglas, Pamela S" sort="Douglas, Pamela S" uniqKey="Douglas P" first="Pamela S" last="Douglas">Pamela S. Douglas</name>
<affiliation><nlm:affiliation>Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Al Khalidi, Hussein" sort="Al Khalidi, Hussein" uniqKey="Al Khalidi H" first="Hussein" last="Al-Khalidi">Hussein Al-Khalidi</name>
<affiliation><nlm:affiliation>Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="White, Jennifer A" sort="White, Jennifer A" uniqKey="White J" first="Jennifer A" last="White">Jennifer A. White</name>
<affiliation><nlm:affiliation>Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Liu, Jingyu" sort="Liu, Jingyu" uniqKey="Liu J" first="Jingyu" last="Liu">Jingyu Liu</name>
<affiliation><nlm:affiliation>Bellerophon Therapeutics Inc., Hampton, New Jersey.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Levy, Howard" sort="Levy, Howard" uniqKey="Levy H" first="Howard" last="Levy">Howard Levy</name>
<affiliation><nlm:affiliation>Bellerophon Therapeutics Inc., Hampton, New Jersey.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Guetta, Victor" sort="Guetta, Victor" uniqKey="Guetta V" first="Victor" last="Guetta">Victor Guetta</name>
<affiliation><nlm:affiliation>Sheba Tel Ha Shomer Hospital, Tel Ha Shomer, Israel.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gibson, C Michael" sort="Gibson, C Michael" uniqKey="Gibson C" first="C Michael" last="Gibson">C Michael Gibson</name>
<affiliation><nlm:affiliation>Beth Israel Deaconess Medical Center, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tanguay, Jean Francois" sort="Tanguay, Jean Francois" uniqKey="Tanguay J" first="Jean-Francois" last="Tanguay">Jean-Francois Tanguay</name>
<affiliation><nlm:affiliation>Montreal Heart Institute, Montreal, Quebec, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vermeersch, Paul" sort="Vermeersch, Paul" uniqKey="Vermeersch P" first="Paul" last="Vermeersch">Paul Vermeersch</name>
<affiliation><nlm:affiliation>Free University, Brussels, Belgium.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Roncalli, Jerome" sort="Roncalli, Jerome" uniqKey="Roncalli J" first="Jérôme" last="Roncalli">Jérôme Roncalli</name>
<affiliation><nlm:affiliation>Rangueil University Hospital, Toulouse, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kasprzak, Jaroslaw D" sort="Kasprzak, Jaroslaw D" uniqKey="Kasprzak J" first="Jaroslaw D" last="Kasprzak">Jaroslaw D. Kasprzak</name>
<affiliation><nlm:affiliation>Medical University of Lodz, Lodz, Poland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Henry, Timothy D" sort="Henry, Timothy D" uniqKey="Henry T" first="Timothy D" last="Henry">Timothy D. Henry</name>
<affiliation><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Frey, Norbert" sort="Frey, Norbert" uniqKey="Frey N" first="Norbert" last="Frey">Norbert Frey</name>
<affiliation><nlm:affiliation>Universitätsklinikum Schleswig-Holstein, Campus Kiel Klinik für Kardiologie und Angiologie, Kiel, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kracoff, Oscar" sort="Kracoff, Oscar" uniqKey="Kracoff O" first="Oscar" last="Kracoff">Oscar Kracoff</name>
<affiliation><nlm:affiliation>Kaplan Medical Center, Rehovot, Israel.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Traverse, Jay H" sort="Traverse, Jay H" uniqKey="Traverse J" first="Jay H" last="Traverse">Jay H. Traverse</name>
<affiliation><nlm:affiliation>Minneapolis Heart Institute, Minneapolis, Minnesota.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chew, Derek P" sort="Chew, Derek P" uniqKey="Chew D" first="Derek P" last="Chew">Derek P. Chew</name>
<affiliation><nlm:affiliation>Flinders University, Adelaide, South Australia, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lopez Sendon, Jose" sort="Lopez Sendon, Jose" uniqKey="Lopez Sendon J" first="Jose" last="Lopez-Sendon">Jose Lopez-Sendon</name>
<affiliation><nlm:affiliation>Hospital Universitario La Paz, Madrid, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Heyrman, Reinilde" sort="Heyrman, Reinilde" uniqKey="Heyrman R" first="Reinilde" last="Heyrman">Reinilde Heyrman</name>
<affiliation><nlm:affiliation>Bellerophon Therapeutics Inc., Hampton, New Jersey.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Krucoff, Mitchell W" sort="Krucoff, Mitchell W" uniqKey="Krucoff M" first="Mitchell W" last="Krucoff">Mitchell W. Krucoff</name>
<affiliation><nlm:affiliation>Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation>
</affiliation>
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<series><title level="j">Journal of the American College of Cardiology</title>
<idno type="eISSN">1558-3597</idno>
<imprint><date when="2016" type="published">2016</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Absorbable Implants</term>
<term>Aged</term>
<term>Coronary Angiography</term>
<term>Coronary Vessels (diagnostic imaging)</term>
<term>Coronary Vessels (surgery)</term>
<term>Double-Blind Method</term>
<term>Electrocardiography</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Heart Ventricles (diagnostic imaging)</term>
<term>Heart Ventricles (physiopathology)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Myocardial Infarction (diagnosis)</term>
<term>Myocardial Infarction (physiopathology)</term>
<term>Myocardial Infarction (surgery)</term>
<term>Percutaneous Coronary Intervention</term>
<term>Postoperative Complications (prevention & control)</term>
<term>Prosthesis Design</term>
<term>Stents</term>
<term>Treatment Outcome</term>
<term>Ventricular Function, Left (physiology)</term>
<term>Ventricular Remodeling</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Coronary Vessels</term>
<term>Heart Ventricles</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Ventricular Function, Left</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Heart Ventricles</term>
<term>Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Postoperative Complications</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Coronary Vessels</term>
<term>Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Absorbable Implants</term>
<term>Aged</term>
<term>Coronary Angiography</term>
<term>Double-Blind Method</term>
<term>Electrocardiography</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Percutaneous Coronary Intervention</term>
<term>Prosthesis Design</term>
<term>Stents</term>
<term>Treatment Outcome</term>
<term>Ventricular Remodeling</term>
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<front><div type="abstract" xml:lang="en">Bioabsorbable cardiac matrix (BCM) is a novel device that attenuates adverse left ventricular (LV) remodeling after large myocardial infarctions in experimental models.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27515331</PMID>
<DateCreated><Year>2016</Year>
<Month>08</Month>
<Day>12</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>06</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>06</Month>
<Day>30</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1558-3597</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>68</Volume>
<Issue>7</Issue>
<PubDate><Year>2016</Year>
<Month>Aug</Month>
<Day>16</Day>
</PubDate>
</JournalIssue>
<Title>Journal of the American College of Cardiology</Title>
<ISOAbbreviation>J. Am. Coll. Cardiol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Bioabsorbable Intracoronary Matrix for Prevention of Ventricular Remodeling After Myocardial Infarction.</ArticleTitle>
<Pagination><MedlinePgn>715-23</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jacc.2016.05.053</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S0735-1097(16)33391-5</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Bioabsorbable cardiac matrix (BCM) is a novel device that attenuates adverse left ventricular (LV) remodeling after large myocardial infarctions in experimental models.</AbstractText>
<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">This study aimed to analyze whether BCM, compared with saline control, would result in less LV dilation and fewer adverse clinical events between baseline and 6 months.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">In an international, randomized, double-blind, controlled trial, 303 subjects with large areas of infarction despite successful primary percutaneous coronary intervention (PCI) of ST-segment elevation myocardial infarction (STEMI) were randomized 2:1 to BCM or saline injected into the infarct-related artery 2 to 5 days after primary PCI. The primary outcome was mean change from baseline in LV end-diastolic volume index (LVEDVI) at 6 months. Secondary outcomes included change in Kansas City Cardiomyopathy Questionnaire score, 6-minute walk time, and New York Heart Association functional class at 6 months. The primary safety endpoint was a composite of cardiovascular death, recurrent MI, target-vessel revascularization, stent thrombosis, significant arrhythmia requiring therapy, or myocardial rupture through 6 months.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In total, 201 subjects were assigned to BCM and 102 to saline control. There was no significant difference in change in LVEDVI from baseline to 6 months between the groups (mean change ± SD: BCM 14.1 ± 28.9 ml/m(2) vs. saline 11.7 ± 26.9 ml/m(2); p = 0.49). There was also no significant difference in the secondary endpoints. The rates of the primary safety outcome were similar between the 2 groups (BCM 11.6% vs. saline 9.1%; p = 0.37).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Intracoronary deployment of BCM 2 to 5 days after successful reperfusion in subjects with large myocardial infarction did not reduce adverse LV remodeling or cardiac clinical events at 6 months. (IK-5001 for the Prevention of Remodeling of the Ventricle and Congestive Heart Failure After Acute Myocardial Infarction [PRESERVATION I]; NCT01226563).</AbstractText>
<CopyrightInformation>Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Rao</LastName>
<ForeName>Sunil V</ForeName>
<Initials>SV</Initials>
<AffiliationInfo><Affiliation>Duke Clinical Research Institute, Durham, North Carolina. Electronic address: sunil.rao@duke.edu.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zeymer</LastName>
<ForeName>Uwe</ForeName>
<Initials>U</Initials>
<AffiliationInfo><Affiliation>Herzzentrum Luwidshafen, Ludwigshafen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Douglas</LastName>
<ForeName>Pamela S</ForeName>
<Initials>PS</Initials>
<AffiliationInfo><Affiliation>Duke Clinical Research Institute, Durham, North Carolina.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Al-Khalidi</LastName>
<ForeName>Hussein</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Duke Clinical Research Institute, Durham, North Carolina.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>White</LastName>
<ForeName>Jennifer A</ForeName>
<Initials>JA</Initials>
<AffiliationInfo><Affiliation>Duke Clinical Research Institute, Durham, North Carolina.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Jingyu</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Bellerophon Therapeutics Inc., Hampton, New Jersey.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Levy</LastName>
<ForeName>Howard</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Bellerophon Therapeutics Inc., Hampton, New Jersey.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Guetta</LastName>
<ForeName>Victor</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Sheba Tel Ha Shomer Hospital, Tel Ha Shomer, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gibson</LastName>
<ForeName>C Michael</ForeName>
<Initials>CM</Initials>
<AffiliationInfo><Affiliation>Beth Israel Deaconess Medical Center, Boston, Massachusetts.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tanguay</LastName>
<ForeName>Jean-Francois</ForeName>
<Initials>JF</Initials>
<AffiliationInfo><Affiliation>Montreal Heart Institute, Montreal, Quebec, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vermeersch</LastName>
<ForeName>Paul</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Free University, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Roncalli</LastName>
<ForeName>Jérôme</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Rangueil University Hospital, Toulouse, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kasprzak</LastName>
<ForeName>Jaroslaw D</ForeName>
<Initials>JD</Initials>
<AffiliationInfo><Affiliation>Medical University of Lodz, Lodz, Poland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Henry</LastName>
<ForeName>Timothy D</ForeName>
<Initials>TD</Initials>
<AffiliationInfo><Affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Frey</LastName>
<ForeName>Norbert</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Universitätsklinikum Schleswig-Holstein, Campus Kiel Klinik für Kardiologie und Angiologie, Kiel, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kracoff</LastName>
<ForeName>Oscar</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Kaplan Medical Center, Rehovot, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Traverse</LastName>
<ForeName>Jay H</ForeName>
<Initials>JH</Initials>
<AffiliationInfo><Affiliation>Minneapolis Heart Institute, Minneapolis, Minnesota.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Chew</LastName>
<ForeName>Derek P</ForeName>
<Initials>DP</Initials>
<AffiliationInfo><Affiliation>Flinders University, Adelaide, South Australia, Australia.</Affiliation>
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<Author ValidYN="Y"><LastName>Lopez-Sendon</LastName>
<ForeName>Jose</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Hospital Universitario La Paz, Madrid, Spain.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Heyrman</LastName>
<ForeName>Reinilde</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Bellerophon Therapeutics Inc., Hampton, New Jersey.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Krucoff</LastName>
<ForeName>Mitchell W</ForeName>
<Initials>MW</Initials>
<AffiliationInfo><Affiliation>Duke Clinical Research Institute, Durham, North Carolina.</Affiliation>
</AffiliationInfo>
</Author>
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<Language>eng</Language>
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<AccessionNumberList><AccessionNumber>NCT01226563</AccessionNumber>
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<PublicationType UI="D016448">Multicenter Study</PublicationType>
<PublicationType UI="D016449">Randomized Controlled Trial</PublicationType>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>J Am Coll Cardiol</MedlineTA>
<NlmUniqueID>8301365</NlmUniqueID>
<ISSNLinking>0735-1097</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D020341" MajorTopicYN="Y">Absorbable Implants</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017023" MajorTopicYN="N">Coronary Angiography</DescriptorName>
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<MeshHeading><DescriptorName UI="D003331" MajorTopicYN="N">Coronary Vessels</DescriptorName>
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<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004311" MajorTopicYN="N">Double-Blind Method</DescriptorName>
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<MeshHeading><DescriptorName UI="D004562" MajorTopicYN="N">Electrocardiography</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName>
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<MeshHeading><DescriptorName UI="D006352" MajorTopicYN="N">Heart Ventricles</DescriptorName>
<QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009203" MajorTopicYN="N">Myocardial Infarction</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D062645" MajorTopicYN="Y">Percutaneous Coronary Intervention</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011183" MajorTopicYN="N">Postoperative Complications</DescriptorName>
<QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011474" MajorTopicYN="N">Prosthesis Design</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015607" MajorTopicYN="Y">Stents</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016277" MajorTopicYN="N">Ventricular Function, Left</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020257" MajorTopicYN="Y">Ventricular Remodeling</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">alginate</Keyword>
<Keyword MajorTopicYN="N">congestive heart failure</Keyword>
<Keyword MajorTopicYN="N">deployment</Keyword>
<Keyword MajorTopicYN="N">echocardiography</Keyword>
<Keyword MajorTopicYN="N">end-diastolic volume</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>04</Month>
<Day>07</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>05</Month>
<Day>10</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2016</Year>
<Month>8</Month>
<Day>13</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="pubmed"><Year>2016</Year>
<Month>8</Month>
<Day>16</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>7</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">27515331</ArticleId>
<ArticleId IdType="pii">S0735-1097(16)33391-5</ArticleId>
<ArticleId IdType="doi">10.1016/j.jacc.2016.05.053</ArticleId>
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