Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens.
Identifieur interne : 000E34 ( PubMed/Corpus ); précédent : 000E33; suivant : 000E35Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens.
Auteurs : Simona John Von Freyend ; Terry Kwok-Schuelein ; Hans J. Netter ; Gholamreza Haqshenas ; Jean-Philippe Semblat ; Christian DoerigSource :
- Pathogens (Basel, Switzerland) [ 2076-0817 ] ; 2017.
Abstract
Intracellular pathogens have evolved a wide range of strategies to not only escape from the immune systems of their hosts, but also to directly exploit a variety of host factors to facilitate the infection process. One such strategy is to subvert host cell signalling pathways to the advantage of the pathogen. Recent research has highlighted that the human serine/threonine kinase PAK, or p21-activated kinase, is a central component of host-pathogen interactions in many infection systems involving viruses, bacteria, and eukaryotic pathogens. PAK paralogues are found in most mammalian tissues, where they play vital roles in a wide range of functions. The role of PAKs in cell proliferation and survival, and their involvement in a number of cancers, is of great interest in the context of drug discovery. In this review we discuss the latest insights into the surprisingly central role human PAK1 plays for the infection by such different infectious disease agents as viruses, bacteria, and parasitic protists. It is our intention to open serious discussion on the applicability of PAK inhibitors for the treatment, not only of neoplastic diseases, which is currently the primary objective of drug discovery research targeting these enzymes, but also of a wide range of infectious diseases.
DOI: 10.3390/pathogens6020017
PubMed: 28430160
Links to Exploration step
pubmed:28430160Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens.</title><author><name sortKey="John Von Freyend, Simona" sort="John Von Freyend, Simona" uniqKey="John Von Freyend S" first="Simona" last="John Von Freyend">Simona John Von Freyend</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. simona.johnvonfreyend@monash.edu.</nlm:affiliation></affiliation></author><author><name sortKey="Kwok Schuelein, Terry" sort="Kwok Schuelein, Terry" uniqKey="Kwok Schuelein T" first="Terry" last="Kwok-Schuelein">Terry Kwok-Schuelein</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. terry.kwok@monash.edu.</nlm:affiliation></affiliation></author><author><name sortKey="Netter, Hans J" sort="Netter, Hans J" uniqKey="Netter H" first="Hans J" last="Netter">Hans J. Netter</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. Hans.Netter@mh.org.au.</nlm:affiliation></affiliation></author><author><name sortKey="Haqshenas, Gholamreza" sort="Haqshenas, Gholamreza" uniqKey="Haqshenas G" first="Gholamreza" last="Haqshenas">Gholamreza Haqshenas</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. gholamreza.haqshenas@monash.edu.</nlm:affiliation></affiliation></author><author><name sortKey="Semblat, Jean Philippe" sort="Semblat, Jean Philippe" uniqKey="Semblat J" first="Jean-Philippe" last="Semblat">Jean-Philippe Semblat</name><affiliation><nlm:affiliation>Inserm UMR-S 1134, Université Paris Diderot, Paris 75013, France. jean-philippe.semblat@inserm.fr.</nlm:affiliation></affiliation></author><author><name sortKey="Doerig, Christian" sort="Doerig, Christian" uniqKey="Doerig C" first="Christian" last="Doerig">Christian Doerig</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. Christian.doerig@monash.edu.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28430160</idno><idno type="pmid">28430160</idno><idno type="doi">10.3390/pathogens6020017</idno><idno type="wicri:Area/PubMed/Corpus">000E34</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E34</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens.</title><author><name sortKey="John Von Freyend, Simona" sort="John Von Freyend, Simona" uniqKey="John Von Freyend S" first="Simona" last="John Von Freyend">Simona John Von Freyend</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. simona.johnvonfreyend@monash.edu.</nlm:affiliation></affiliation></author><author><name sortKey="Kwok Schuelein, Terry" sort="Kwok Schuelein, Terry" uniqKey="Kwok Schuelein T" first="Terry" last="Kwok-Schuelein">Terry Kwok-Schuelein</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. terry.kwok@monash.edu.</nlm:affiliation></affiliation></author><author><name sortKey="Netter, Hans J" sort="Netter, Hans J" uniqKey="Netter H" first="Hans J" last="Netter">Hans J. Netter</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. Hans.Netter@mh.org.au.</nlm:affiliation></affiliation></author><author><name sortKey="Haqshenas, Gholamreza" sort="Haqshenas, Gholamreza" uniqKey="Haqshenas G" first="Gholamreza" last="Haqshenas">Gholamreza Haqshenas</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. gholamreza.haqshenas@monash.edu.</nlm:affiliation></affiliation></author><author><name sortKey="Semblat, Jean Philippe" sort="Semblat, Jean Philippe" uniqKey="Semblat J" first="Jean-Philippe" last="Semblat">Jean-Philippe Semblat</name><affiliation><nlm:affiliation>Inserm UMR-S 1134, Université Paris Diderot, Paris 75013, France. jean-philippe.semblat@inserm.fr.</nlm:affiliation></affiliation></author><author><name sortKey="Doerig, Christian" sort="Doerig, Christian" uniqKey="Doerig C" first="Christian" last="Doerig">Christian Doerig</name><affiliation><nlm:affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. Christian.doerig@monash.edu.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Pathogens (Basel, Switzerland)</title><idno type="ISSN">2076-0817</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Intracellular pathogens have evolved a wide range of strategies to not only escape from the immune systems of their hosts, but also to directly exploit a variety of host factors to facilitate the infection process. One such strategy is to subvert host cell signalling pathways to the advantage of the pathogen. Recent research has highlighted that the human serine/threonine kinase PAK, or p21-activated kinase, is a central component of host-pathogen interactions in many infection systems involving viruses, bacteria, and eukaryotic pathogens. PAK paralogues are found in most mammalian tissues, where they play vital roles in a wide range of functions. The role of PAKs in cell proliferation and survival, and their involvement in a number of cancers, is of great interest in the context of drug discovery. In this review we discuss the latest insights into the surprisingly central role human PAK1 plays for the infection by such different infectious disease agents as viruses, bacteria, and parasitic protists. It is our intention to open serious discussion on the applicability of PAK inhibitors for the treatment, not only of neoplastic diseases, which is currently the primary objective of drug discovery research targeting these enzymes, but also of a wide range of infectious diseases.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">28430160</PMID><DateCreated><Year>2017</Year><Month>04</Month><Day>21</Day></DateCreated><DateRevised><Year>2017</Year><Month>08</Month><Day>16</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Print">2076-0817</ISSN><JournalIssue CitedMedium="Print"><Volume>6</Volume><Issue>2</Issue><PubDate><Year>2017</Year><Month>04</Month><Day>21</Day></PubDate></JournalIssue><Title>Pathogens (Basel, Switzerland)</Title><ISOAbbreviation>Pathogens</ISOAbbreviation></Journal><ArticleTitle>Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E17</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/pathogens6020017</ELocationID><Abstract><AbstractText>Intracellular pathogens have evolved a wide range of strategies to not only escape from the immune systems of their hosts, but also to directly exploit a variety of host factors to facilitate the infection process. One such strategy is to subvert host cell signalling pathways to the advantage of the pathogen. Recent research has highlighted that the human serine/threonine kinase PAK, or p21-activated kinase, is a central component of host-pathogen interactions in many infection systems involving viruses, bacteria, and eukaryotic pathogens. PAK paralogues are found in most mammalian tissues, where they play vital roles in a wide range of functions. The role of PAKs in cell proliferation and survival, and their involvement in a number of cancers, is of great interest in the context of drug discovery. In this review we discuss the latest insights into the surprisingly central role human PAK1 plays for the infection by such different infectious disease agents as viruses, bacteria, and parasitic protists. It is our intention to open serious discussion on the applicability of PAK inhibitors for the treatment, not only of neoplastic diseases, which is currently the primary objective of drug discovery research targeting these enzymes, but also of a wide range of infectious diseases.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>John Von Freyend</LastName><ForeName>Simona</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. simona.johnvonfreyend@monash.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kwok-Schuelein</LastName><ForeName>Terry</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. terry.kwok@monash.edu.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Cancer Program, Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia. terry.kwok@monash.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Netter</LastName><ForeName>Hans J</ForeName><Initials>HJ</Initials><AffiliationInfo><Affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. Hans.Netter@mh.org.au.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Victorian Infectious Diseases Reference Laboratory, Melbourne Health, The Peter Doherty Institute, Melbourne, Victoria 3000, Australia. Hans.Netter@mh.org.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haqshenas</LastName><ForeName>Gholamreza</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. gholamreza.haqshenas@monash.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Semblat</LastName><ForeName>Jean-Philippe</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Inserm UMR-S 1134, Université Paris Diderot, Paris 75013, France. jean-philippe.semblat@inserm.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Doerig</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia. Christian.doerig@monash.edu.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>04</Month><Day>21</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Pathogens</MedlineTA><NlmUniqueID>101596317</NlmUniqueID><ISSNLinking>2076-0817</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>J Intern Med. 2010 May;267(5):473-82</RefSource><PMID Version="1">20433575</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Curr Opin Virol. 2014 Feb;4:24-31</RefSource><PMID Version="1">24525291</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2010 Sep 23;6(9):e1001121</RefSource><PMID Version="1">20886108</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biol Chem. 2006 Jan;387(1):79-86</RefSource><PMID Version="1">16497167</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbiol Immunol. 2012 Jun;56(6):351-5</RefSource><PMID Version="1">22486440</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 1998 May 29;93(5):815-26</RefSource><PMID Version="1">9630225</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Microbiol. 2001 May;40(4):815-23</RefSource><PMID Version="1">11401689</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Logist. 2012 Apr 1;2(2):132-135</RefSource><PMID Version="1">23162744</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Biochem. 2009 Jul 1;107(4):579-85</RefSource><PMID Version="1">19350548</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2006 Jan;80(1):130-7</RefSource><PMID Version="1">16352537</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Signal. 2014 Sep;26(9):2060-9</RefSource><PMID Version="1">24794532</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2012;7(12):e51831</RefSource><PMID Version="1">23272175</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biochem Biophys Res Commun. 2011 Oct 28;414(3):569-74</RefSource><PMID Version="1">21982772</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Immunol. 2006 Oct;36(10):2735-44</RefSource><PMID Version="1">16955522</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 2003 Sep 19;301(5640):1734-6</RefSource><PMID Version="1">14500986</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Genomics. 2004 Oct 12;5:79</RefSource><PMID Version="1">15479470</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Host Microbe. 2009 Mar 19;5(3):259-72</RefSource><PMID Version="1">19286135</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genes Cells. 2000 Dec;5(12):1017-27</RefSource><PMID Version="1">11168588</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2007 Apr 20;282(16):11836-48</RefSource><PMID Version="1">17255101</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Mol Signal. 2014 Aug 01;9:7</RefSource><PMID Version="1">25093037</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8990-5</RefSource><PMID Version="1">15951429</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prog Mol Biol Transl Sci. 2012;106:171-87</RefSource><PMID Version="1">22340718</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2012 Feb;80(2):768-77</RefSource><PMID Version="1">22104111</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2015 Apr 30;11(4):e1004731</RefSource><PMID Version="1">25928849</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Mol Life Sci. 2008 Jun;65(12):1900-15</RefSource><PMID Version="1">18327664</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>MBio. 2015 Sep 08;6(5):e01309-15</RefSource><PMID Version="1">26350970</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Oncotarget. 2011 Jun;2(6):491-6</RefSource><PMID Version="1">21653999</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Mol Life Sci. 2014 Apr;71(7):1245-63</RefSource><PMID Version="1">24221133</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Microbiol. 2001 Jul;3(7):439-47</RefSource><PMID Version="1">11437830</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2010 Apr 17;375(9723):1388-402</RefSource><PMID Version="1">20399979</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2015 Feb;89(3):1851-66</RefSource><PMID Version="1">25428868</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2004 Feb 13;279(7):6196-203</RefSource><PMID Version="1">14645234</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Immunol Cell Biol. 2011 Nov;89(8):836-43</RefSource><PMID Version="1">21423264</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2015 Feb 27;11(2):e1004670</RefSource><PMID Version="1">25723550</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2011;6(12):e29566</RefSource><PMID Version="1">22216318</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2013 Jan;87(2):735-45</RefSource><PMID Version="1">23115275</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2015 Nov 18;90(3):1522-33</RefSource><PMID Version="1">26581992</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Med Chem. 2015 Jan 8;58(1):111-29</RefSource><PMID Version="1">25415869</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Chem Biol. 2008 Apr;15(4):322-31</RefSource><PMID Version="1">18420139</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2008 Nov;4(11):e1000201</RefSource><PMID Version="1">18989463</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sci Rep. 2016 Jan 13;6:19294</RefSource><PMID Version="1">26757826</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2010 Apr;84(8):3935-48</RefSource><PMID Version="1">20147394</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2013 Sep 24;8(9):e75577</RefSource><PMID Version="1">24086576</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann N Y Acad Sci. 2007 Jan;1096:18-23</RefSource><PMID Version="1">17405911</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Blood. 2011 Nov 10;118(19):5344-54</RefSource><PMID Version="1">21881052</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Microbiol. 2002 Sep;4(9):557-69</RefSource><PMID Version="1">12390349</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Microbiol. 2013 May 30;13:125</RefSource><PMID Version="1">23721065</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Rev Cancer. 2014 Jan;14(1):13-25</RefSource><PMID Version="1">24505617</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Biol Cell. 2008 Jul;19(7):2857-69</RefSource><PMID Version="1">18448666</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbes Infect. 2004 Apr;6(5):460-7</RefSource><PMID Version="1">15109960</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trends Parasitol. 2015 Jul;31(7):306-14</RefSource><PMID Version="1">25951781</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Virol. 2016 Nov;161(11):2991-3002</RefSource><PMID Version="1">27465567</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Int J Biochem Cell Biol. 2010 Jan;42(1):13-6</RefSource><PMID Version="1">19747561</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Traffic. 2000 Feb;1(2):100-6</RefSource><PMID Version="1">11208090</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2012;8(4):e1002657</RefSource><PMID Version="1">22536154</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2011 Jan 6;469(7328):107-11</RefSource><PMID Version="1">21170023</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Intern Med. 2010 May;267(5):526-42</RefSource><PMID Version="1">20433579</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2006 May;74(5):2613-8</RefSource><PMID Version="1">16622197</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Microbiol. 2013 Jan;15(1):53-62</RefSource><PMID Version="1">23083122</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Cell Biol. 2009 May;11(5):510-20</RefSource><PMID Version="1">19404330</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Commun Signal. 2013 Nov 22;11:90</RefSource><PMID Version="1">24267514</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Cell Biol. 1999 Dec;78(12):911-24</RefSource><PMID Version="1">10669110</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Blood. 2009 Mar 19;113(12 ):2695-705</RefSource><PMID Version="1">19124833</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Host Microbe. 2010 Aug 19;8(2):208-18</RefSource><PMID Version="1">20709297</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer Res. 2003 Dec 15;63(24):8837-47</RefSource><PMID Version="1">14695200</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2010 Sep 16;6(9):e1001110</RefSource><PMID Version="1">20862315</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2008 Mar;82(6):2918-29</RefSource><PMID Version="1">18094167</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasitol Int. 2013 Oct;62(5):475-82</RefSource><PMID Version="1">23624149</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Virology. 2007 Nov 10;368(1):7-16</RefSource><PMID Version="1">17632197</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Virology. 2011 Jan 20;409(2):234-50</RefSource><PMID Version="1">21056892</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2000 Jun 30;275(26):19693-9</RefSource><PMID Version="1">10779525</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Gastroenterology. 2012 Jul;143(1):199-212.e4</RefSource><PMID Version="1">22484303</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Virus Res. 2011 Jan;155(1):376-80</RefSource><PMID Version="1">21093504</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer Prev Res (Phila). 2012 Jan;5(1):18-23</RefSource><PMID Version="1">22219162</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Rev Microbiol. 2009 Apr;7(4):274-86</RefSource><PMID Version="1">19287450</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Microbiol. 2012 Sep;14(9):1434-54</RefSource><PMID Version="1">22533473</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbiology. 2011 Jan;157(Pt 1):234-50</RefSource><PMID Version="1">20929955</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasite. 2014;21:11</RefSource><PMID Version="1">24626257</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Med. 2001 Nov;7(11):1217-24</RefSource><PMID Version="1">11689886</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2010 May;84(10):5336-50</RefSource><PMID Version="1">20237079</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Invest Dermatol. 2015 Jan;135(1):142-50</RefSource><PMID Version="1">25089661</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>EMBO J. 1995 Feb 1;14(3):484-91</RefSource><PMID Version="1">7859737</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Rev Immunol. 2005 Oct;5(10):749-59</RefSource><PMID Version="1">16175180</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Oncol. 2009 Apr;10(4):321-2</RefSource><PMID Version="1">19350698</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biochem Biophys Res Commun. 2009 Jan 16;378(3):656-61</RefSource><PMID Version="1">19061866</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trends Microbiol. 2008 Apr;16(4):173-80</RefSource><PMID Version="1">18353648</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Struct Funct. 2002 Apr;27(2):91-8</RefSource><PMID Version="1">12207050</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Curr Biol. 1997 Mar 1;7(3):202-10</RefSource><PMID Version="1">9395435</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>World J Gastroenterol. 2015 Oct 14;21(38):10732-8</RefSource><PMID Version="1">26478665</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Cell Biol. 2008 Nov;10(11):1356-64</RefSource><PMID Version="1">18931661</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Biol. 2003 Jun 9;161(5):845-51</RefSource><PMID Version="1">12796474</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trends Microbiol. 1997 Mar;5(3):109-14</RefSource><PMID Version="1">9080609</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Curr Opin Microbiol. 2012 Aug;15(4):490-9</RefSource><PMID Version="1">22749376</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbiology. 2012 Sep;158(Pt 9):2384-98</RefSource><PMID Version="1">22723286</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasitology. 2006;132 Suppl:S49-60</RefSource><PMID Version="1">17018165</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2012;8(6):e1002754</RefSource><PMID Version="1">22719252</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Med Chem. 2016 Jun 9;59(11):5520-41</RefSource><PMID Version="1">27167326</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2003 May;71(5):2787-97</RefSource><PMID Version="1">12704153</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2013 Apr;87(7):4121-6</RefSource><PMID Version="1">23365433</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Exp Med. 1999 May 3;189(9):1479-88</RefSource><PMID Version="1">10224288</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2012;7(8):e44072</RefSource><PMID Version="1">22952878</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2013;9(10):e1003668</RefSource><PMID Version="1">24098123</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Sci. 2003 Nov 1;116(Pt 21):4345-58</RefSource><PMID Version="1">12966169</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2005 Feb 11;280(6):4279-88</RefSource><PMID Version="1">15561713</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Sci. 2008 Nov 15;121(Pt 22):3729-36</RefSource><PMID Version="1">18940914</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Microbiol. 1996 Apr;20(2):263-71</RefSource><PMID Version="1">8733226</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Exp Med. 1998 Oct 5;188(7):1277-86</RefSource><PMID Version="1">9763607</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Rev Microbiol. 2008 Jan;6(1):53-66</RefSource><PMID Version="1">18026123</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sci Signal. 2009 Nov 17;2(97):ra74</RefSource><PMID Version="1">19920252</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Int Immunopharmacol. 2013 Dec;17(4):1185-97</RefSource><PMID Version="1">24263067</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2011;6(11):e27637</RefSource><PMID Version="1">22096607</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2010 May 18;107(20):9346-51</RefSource><PMID Version="1">20439710</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2005 Dec;79(23):14976-80</RefSource><PMID Version="1">16282498</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Microbiol. 2011 Jun;13(6):836-45</RefSource><PMID Version="1">21371233</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neuroimmune Pharmacol. 2011 Jun;6(2):230-46</RefSource><PMID Version="1">21336563</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Yonsei Med J. 2006 Dec 31;47(6):862-9</RefSource><PMID Version="1">17191317</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Biol. 2011 Oct 3;195(1):7-17</RefSource><PMID Version="1">21969466</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>EMBO J. 2008 Apr 9;27(7):956-69</RefSource><PMID Version="1">18323776</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2004 Apr;78(8):4085-97</RefSource><PMID Version="1">15047825</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Microbes Infect. 2012 Nov;14 (14 ):1340-51</RefSource><PMID Version="1">23010292</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2016 Nov 14;90(23 ):10945-10950</RefSource><PMID Version="1">27681139</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Gen Virol. 2011 Jan;92(Pt 1):18-30</RefSource><PMID Version="1">20943887</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Virology. 2010 Jun 5;401(2):266-79</RefSource><PMID Version="1">20334889</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Logist. 2012 Apr 1;2(2):126-131</RefSource><PMID Version="1">23125952</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 1996 Sep;70(9):6157-61</RefSource><PMID Version="1">8709241</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2008 Mar 21;4(3):e1000031</RefSource><PMID Version="1">18369477</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Submicrosc Cytol Pathol. 1999 Jul;31(3):325-33</RefSource><PMID Version="1">10626001</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Helicobacter. 2010 Jun;15(3):163-76</RefSource><PMID Version="1">20557357</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2004 May;72(5):3011-21</RefSource><PMID Version="1">15102814</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Pathog. 2011 Mar;7(3):e1001329</RefSource><PMID Version="1">21483486</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>FEBS Lett. 2004 Jun 4;567(2-3):230-8</RefSource><PMID Version="1">15178328</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasitol Res. 2005 Jun;96(3):171-7</RefSource><PMID Version="1">15864650</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2011 Apr 8;286(14):12554-64</RefSource><PMID Version="1">21321123</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Oncogene. 2009 Jul 16;28(28):2545-55</RefSource><PMID Version="1">19465939</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2000 Dec 15;275(50):39779-85</RefSource><PMID Version="1">11016939</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>EMBO J. 2008 Apr 9;27(7):970-81</RefSource><PMID Version="1">18354494</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Med. 2006 Dec;3(12):e528</RefSource><PMID Version="1">17194200</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2013 Mar 29;288(13):8887-97</RefSource><PMID Version="1">23393142</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2002 Aug;70(8):4571-80</RefSource><PMID Version="1">12117970</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Virol. 2014 Nov;88(22):13047-63</RefSource><PMID Version="1">25165116</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Blood. 2005 Dec 1;106(12):3962-9</RefSource><PMID Version="1">16099876</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2009 May 26;106(21):8707-12</RefSource><PMID Version="1">19435845</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biochemistry. 2011 Feb 15;50(6):917-9</RefSource><PMID Version="1">21235237</PMID></CommentsCorrections></CommentsCorrectionsList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">bacteria</Keyword><Keyword MajorTopicYN="Y">host-pathogen interactions</Keyword><Keyword MajorTopicYN="Y">kinase</Keyword><Keyword MajorTopicYN="Y">parasite</Keyword><Keyword MajorTopicYN="Y">signalling</Keyword><Keyword MajorTopicYN="Y">virus</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>01</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>03</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>04</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>4</Month><Day>22</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28430160</ArticleId><ArticleId IdType="pii">pathogens6020017</ArticleId><ArticleId IdType="doi">10.3390/pathogens6020017</ArticleId><ArticleId IdType="pmc">PMC5488651</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour 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