AustralieFrV1, PubMed, Corpus, bibRecord, 000D22

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Identifieur interne : 000D22 ( PubMed/Corpus ); précédent : 000D21; suivant : 000D23

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Auteurs : Philip C. Haycock ; Stephen Burgess ; Aayah Nounu ; Jie Zheng ; George N. Okoli ; Jack Bowden ; Kaitlin Hazel Wade ; Nicholas J. Timpson ; David M. Evans ; Peter Willeit ; Abraham Aviv ; Tom R. Gaunt ; Gibran Hemani ; Massimo Mangino ; Hayley Patricia Ellis ; Kathreena M. Kurian ; Karen A. Pooley ; Rosalind A. Eeles ; Jeffrey E. Lee ; Shenying Fang ; Wei V. Chen ; Matthew H. Law ; Lisa M. Bowdler ; Mark M. Iles ; Qiong Yang ; Bradford B. Worrall ; Hugh Stephen Markus ; Rayjean J. Hung ; Chris I. Amos ; Amanda B. Spurdle ; Deborah J. Thompson ; Tracy A. O'Mara ; Brian Wolpin ; Laufey Amundadottir ; Rachael Stolzenberg-Solomon ; Antonia Trichopoulou ; N Charlotte Onland-Moret ; Eiliv Lund ; Eric J. Duell ; Federico Canzian ; Gianluca Severi ; Kim Overvad ; Marc J. Gunter ; Rosario Tumino ; Ulrika Svenson ; Andre Van Rij ; Annette F. Baas ; Matthew J. Bown ; Nilesh J. Samani ; Femke N G. Van T'Hof ; Gerard Tromp ; Gregory T. Jones ; Helena Kuivaniemi ; James R. Elmore ; Mattias Johansson ; James Mckay ; Ghislaine Scelo ; Robert Carreras-Torres ; Valerie Gaborieau ; Paul Brennan ; Paige M. Bracci ; Rachel E. Neale ; Sara H. Olson ; Steven Gallinger ; Donghui Li ; Gloria M. Petersen ; Harvey A. Risch ; Alison P. Klein ; Jiali Han ; Christian C. Abnet ; Neal D. Freedman ; Philip R. Taylor ; John M. Maris ; Katja K. Aben ; Lambertus A. Kiemeney ; Sita H. Vermeulen ; John K. Wiencke ; Kyle M. Walsh ; Margaret Wrensch ; Terri Rice ; Clare Turnbull ; Kevin Litchfield ; Lavinia Paternoster ; Marie Standl ; Gonçalo R. Abecasis ; John Paul Sangiovanni ; Yong Li ; Vladan Mijatovic ; Yadav Sapkota ; Siew-Kee Low ; Krina T. Zondervan ; Grant W. Montgomery ; Dale R. Nyholt ; David A. Van Heel ; Karen Hunt ; Dan E. Arking ; Foram N. Ashar ; Nona Sotoodehnia ; Daniel Woo ; Jonathan Rosand ; Mary E. Comeau ; W Mark Brown ; Edwin K. Silverman ; John E. Hokanson ; Michael H. Cho ; Jennie Hui ; Manuel A. Ferreira ; Philip J. Thompson ; Alanna C. Morrison ; Janine F. Felix ; Nicholas L. Smith ; Angela M. Christiano ; Lynn Petukhova ; Regina C. Betz ; Xing Fan ; Xuejun Zhang ; Caihong Zhu ; Carl D. Langefeld ; Susan D. Thompson ; Feijie Wang ; Xu Lin ; David A. Schwartz ; Tasha Fingerlin ; Jerome I. Rotter ; Mary Frances Cotch ; Richard A. Jensen ; Matthias Munz ; Henrik Dommisch ; Arne S. Schaefer ; Fang Han ; Hanna M. Ollila ; Ryan P. Hillary ; Omar Albagha ; Stuart H. Ralston ; Chenjie Zeng ; Wei Zheng ; Xiao-Ou Shu ; Andre Reis ; Steffen Uebe ; Ulrike Hüffmeier ; Yoshiya Kawamura ; Takeshi Otowa ; Tsukasa Sasaki ; Martin Lloyd Hibberd ; Sonia Davila ; Gang Xie ; Katherine Siminovitch ; Jin-Xin Bei ; Yi-Xin Zeng ; Asta Försti ; Bowang Chen ; Stefano Landi ; Andre Franke ; Annegret Fischer ; David Ellinghaus ; Carlos Flores ; Imre Noth ; Shwu-Fan Ma ; Jia Nee Foo ; Jianjun Liu ; Jong-Won Kim ; David G. Cox ; Olivier Delattre ; Olivier Mirabeau ; Christine F. Skibola ; Clara S. Tang ; Merce Garcia-Barcelo ; Kai-Ping Chang ; Wen-Hui Su ; Yu-Sun Chang ; Nicholas G. Martin ; Scott Gordon ; Tracey D. Wade ; Chaeyoung Lee ; Michiaki Kubo ; Pei-Chieng Cha ; Yusuke Nakamura ; Daniel Levy ; Masayuki Kimura ; Shih-Jen Hwang ; Steven Hunt ; Tim Spector ; Nicole Soranzo ; Ani W. Manichaikul ; R Graham Barr ; Bratati Kahali ; Elizabeth Speliotes ; Laura M. Yerges-Armstrong ; Ching-Yu Cheng ; Jost B. Jonas ; Tien Yin Wong ; Isabella Fogh ; Kuang Lin ; John F. Powell ; Kenneth Rice ; Caroline L. Relton ; Richard M. Martin ; George Davey Smith

Source :

JAMA oncology [ 2374-2445 ] ; 2017.

RBID : pubmed:28241208

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Cardiovascular Diseases (genetics), Female, Genetic Predisposition to Disease (genetics), Genome-Wide Association Study, Germ-Line Mutation, Humans, Male, Mendelian Randomization Analysis (methods), Middle Aged, Neoplasms (genetics), Polymorphism, Single Nucleotide, Risk Assessment (methods), Telomere (genetics), Telomere Homeostasis (genetics).
MESH :
- genetics : Cardiovascular Diseases, Genetic Predisposition to Disease, Neoplasms, Telomere, Telomere Homeostasis.
- methods : Mendelian Randomization Analysis, Risk Assessment.
- Adult, Aged, Aged, 80 and over, Female, Genome-Wide Association Study, Germ-Line Mutation, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide.

Abstract

The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.

DOI: 10.1001/jamaoncol.2016.5945
PubMed: 28241208

Links to Exploration step

pubmed:28241208

Le document en format XML

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<author><name sortKey="Haycock, Philip C" sort="Haycock, Philip C" uniqKey="Haycock P" first="Philip C" last="Haycock">Philip C. Haycock</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
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<author><name sortKey="Burgess, Stephen" sort="Burgess, Stephen" uniqKey="Burgess S" first="Stephen" last="Burgess">Stephen Burgess</name>
<affiliation><nlm:affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.</nlm:affiliation>
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<author><name sortKey="Nounu, Aayah" sort="Nounu, Aayah" uniqKey="Nounu A" first="Aayah" last="Nounu">Aayah Nounu</name>
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<author><name sortKey="Zheng, Jie" sort="Zheng, Jie" uniqKey="Zheng J" first="Jie" last="Zheng">Jie Zheng</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Okoli, George N" sort="Okoli, George N" uniqKey="Okoli G" first="George N" last="Okoli">George N. Okoli</name>
<affiliation><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
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<author><name sortKey="Bowden, Jack" sort="Bowden, Jack" uniqKey="Bowden J" first="Jack" last="Bowden">Jack Bowden</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
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<author><name sortKey="Wade, Kaitlin Hazel" sort="Wade, Kaitlin Hazel" uniqKey="Wade K" first="Kaitlin Hazel" last="Wade">Kaitlin Hazel Wade</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
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<author><name sortKey="Timpson, Nicholas J" sort="Timpson, Nicholas J" uniqKey="Timpson N" first="Nicholas J" last="Timpson">Nicholas J. Timpson</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Evans, David M" sort="Evans, David M" uniqKey="Evans D" first="David M" last="Evans">David M. Evans</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England4University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Willeit, Peter" sort="Willeit, Peter" uniqKey="Willeit P" first="Peter" last="Willeit">Peter Willeit</name>
<affiliation><nlm:affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge, England5Department of Neurology, Innsbruck Medical University, Austria.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Aviv, Abraham" sort="Aviv, Abraham" uniqKey="Aviv A" first="Abraham" last="Aviv">Abraham Aviv</name>
<affiliation><nlm:affiliation>Center of Human Development and Aging, Department of Pediatrics, New Jersey Medical School, Rutgers, The State University of New Jersey.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Gaunt, Tom R" sort="Gaunt, Tom R" uniqKey="Gaunt T" first="Tom R" last="Gaunt">Tom R. Gaunt</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Hemani, Gibran" sort="Hemani, Gibran" uniqKey="Hemani G" first="Gibran" last="Hemani">Gibran Hemani</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name>
<affiliation><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London England8NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ellis, Hayley Patricia" sort="Ellis, Hayley Patricia" uniqKey="Ellis H" first="Hayley Patricia" last="Ellis">Hayley Patricia Ellis</name>
<affiliation><nlm:affiliation>Brain Tumour Research Group, Institute of Clinical Neuroscience, Learning and Research Building, Southmead Hospital, University of Bristol.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kurian, Kathreena M" sort="Kurian, Kathreena M" uniqKey="Kurian K" first="Kathreena M" last="Kurian">Kathreena M. Kurian</name>
<affiliation><nlm:affiliation>Brain Tumour Research Group, Institute of Clinical Neuroscience, Learning and Research Building, Southmead Hospital, University of Bristol.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pooley, Karen A" sort="Pooley, Karen A" uniqKey="Pooley K" first="Karen A" last="Pooley">Karen A. Pooley</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Eeles, Rosalind A" sort="Eeles, Rosalind A" uniqKey="Eeles R" first="Rosalind A" last="Eeles">Rosalind A. Eeles</name>
<affiliation><nlm:affiliation>The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lee, Jeffrey E" sort="Lee, Jeffrey E" uniqKey="Lee J" first="Jeffrey E" last="Lee">Jeffrey E. Lee</name>
<affiliation><nlm:affiliation>Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fang, Shenying" sort="Fang, Shenying" uniqKey="Fang S" first="Shenying" last="Fang">Shenying Fang</name>
<affiliation><nlm:affiliation>Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chen, Wei V" sort="Chen, Wei V" uniqKey="Chen W" first="Wei V" last="Chen">Wei V. Chen</name>
<affiliation><nlm:affiliation>Department of Clinical Applications & Support, The University of Texas MD Anderson Cancer Center, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Law, Matthew H" sort="Law, Matthew H" uniqKey="Law M" first="Matthew H" last="Law">Matthew H. Law</name>
<affiliation><nlm:affiliation>Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bowdler, Lisa M" sort="Bowdler, Lisa M" uniqKey="Bowdler L" first="Lisa M" last="Bowdler">Lisa M. Bowdler</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Iles, Mark M" sort="Iles, Mark M" uniqKey="Iles M" first="Mark M" last="Iles">Mark M. Iles</name>
<affiliation><nlm:affiliation>Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Yang, Qiong" sort="Yang, Qiong" uniqKey="Yang Q" first="Qiong" last="Yang">Qiong Yang</name>
<affiliation><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Worrall, Bradford B" sort="Worrall, Bradford B" uniqKey="Worrall B" first="Bradford B" last="Worrall">Bradford B. Worrall</name>
<affiliation><nlm:affiliation>Departments of Neurology and Public Health Sciences, University of Virginia Charlottesville, Virginia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Markus, Hugh Stephen" sort="Markus, Hugh Stephen" uniqKey="Markus H" first="Hugh Stephen" last="Markus">Hugh Stephen Markus</name>
<affiliation><nlm:affiliation>Department of Clinical Neurosciences, University of Cambridge, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hung, Rayjean J" sort="Hung, Rayjean J" uniqKey="Hung R" first="Rayjean J" last="Hung">Rayjean J. Hung</name>
<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada21Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Amos, Chris I" sort="Amos, Chris I" uniqKey="Amos C" first="Chris I" last="Amos">Chris I. Amos</name>
<affiliation><nlm:affiliation>Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B" last="Spurdle">Amanda B. Spurdle</name>
<affiliation><nlm:affiliation>Genetics and Computational Biology Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Thompson, Deborah J" sort="Thompson, Deborah J" uniqKey="Thompson D" first="Deborah J" last="Thompson">Deborah J. Thompson</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="O Mara, Tracy A" sort="O Mara, Tracy A" uniqKey="O Mara T" first="Tracy A" last="O'Mara">Tracy A. O'Mara</name>
<affiliation><nlm:affiliation>Genetics and Computational Biology Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wolpin, Brian" sort="Wolpin, Brian" uniqKey="Wolpin B" first="Brian" last="Wolpin">Brian Wolpin</name>
<affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Amundadottir, Laufey" sort="Amundadottir, Laufey" uniqKey="Amundadottir L" first="Laufey" last="Amundadottir">Laufey Amundadottir</name>
<affiliation><nlm:affiliation>Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Stolzenberg Solomon, Rachael" sort="Stolzenberg Solomon, Rachael" uniqKey="Stolzenberg Solomon R" first="Rachael" last="Stolzenberg-Solomon">Rachael Stolzenberg-Solomon</name>
<affiliation><nlm:affiliation>Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name>
<affiliation><nlm:affiliation>Hellenic Health Foundation, Athens, Greece28WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lund, Eiliv" sort="Lund, Eiliv" uniqKey="Lund E" first="Eiliv" last="Lund">Eiliv Lund</name>
<affiliation><nlm:affiliation>Institute of Community Medicine, UiT The Arctic University of Norway, Tromso, Norway.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Duell, Eric J" sort="Duell, Eric J" uniqKey="Duell E" first="Eric J" last="Duell">Eric J. Duell</name>
<affiliation><nlm:affiliation>Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Canzian, Federico" sort="Canzian, Federico" uniqKey="Canzian F" first="Federico" last="Canzian">Federico Canzian</name>
<affiliation><nlm:affiliation>Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name>
<affiliation><nlm:affiliation>Université Paris-Saclay, Université Paris-Sud, UVSQ, CESP, INSERM, Villejuif, France34Institut Gustave Roussy, Villejuif, France35Human Genetics Foundation (HuGeF), Torino, Italy36Cancer Council Victoria and University of Melbourne, Melbourne, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name>
<affiliation><nlm:affiliation>Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J" last="Gunter">Marc J. Gunter</name>
<affiliation><nlm:affiliation>School of Public Health, Imperial College London, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name>
<affiliation><nlm:affiliation>Cancer Registry, Azienda Ospedaliera "Civile M.P. Arezzo," Ragusa, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Svenson, Ulrika" sort="Svenson, Ulrika" uniqKey="Svenson U" first="Ulrika" last="Svenson">Ulrika Svenson</name>
<affiliation><nlm:affiliation>Department of Medical Biosciences, Umea University, Umea, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Rij, Andre" sort="Van Rij, Andre" uniqKey="Van Rij A" first="Andre" last="Van Rij">Andre Van Rij</name>
<affiliation><nlm:affiliation>Surgery Department, University of Otago, Dunedin, New Zealand.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Baas, Annette F" sort="Baas, Annette F" uniqKey="Baas A" first="Annette F" last="Baas">Annette F. Baas</name>
<affiliation><nlm:affiliation>Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bown, Matthew J" sort="Bown, Matthew J" uniqKey="Bown M" first="Matthew J" last="Bown">Matthew J. Bown</name>
<affiliation><nlm:affiliation>Department of Cardiovascular Sciences and the NIHR Leicester, Cardiovascular Biomedical Research Unit, University of Leicester, Glenfield Hospital, Leicester, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J" last="Samani">Nilesh J. Samani</name>
<affiliation><nlm:affiliation>Department of Cardiovascular Sciences and the NIHR Leicester, Cardiovascular Biomedical Research Unit, University of Leicester, Glenfield Hospital, Leicester, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van T Hof, Femke N G" sort="Van T Hof, Femke N G" uniqKey="Van T Hof F" first="Femke N G" last="Van T'Hof">Femke N G. Van T'Hof</name>
<affiliation><nlm:affiliation>Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tromp, Gerard" sort="Tromp, Gerard" uniqKey="Tromp G" first="Gerard" last="Tromp">Gerard Tromp</name>
<affiliation><nlm:affiliation>Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa46The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jones, Gregory T" sort="Jones, Gregory T" uniqKey="Jones G" first="Gregory T" last="Jones">Gregory T. Jones</name>
<affiliation><nlm:affiliation>Surgery Department, University of Otago, Dunedin, New Zealand.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kuivaniemi, Helena" sort="Kuivaniemi, Helena" uniqKey="Kuivaniemi H" first="Helena" last="Kuivaniemi">Helena Kuivaniemi</name>
<affiliation><nlm:affiliation>Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa46The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Elmore, James R" sort="Elmore, James R" uniqKey="Elmore J" first="James R" last="Elmore">James R. Elmore</name>
<affiliation><nlm:affiliation>Department of Vascular and Endovascular Surgery, Geisinger Health System, Danville, Pennsylvania.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Johansson, Mattias" sort="Johansson, Mattias" uniqKey="Johansson M" first="Mattias" last="Johansson">Mattias Johansson</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mckay, James" sort="Mckay, James" uniqKey="Mckay J" first="James" last="Mckay">James Mckay</name>
<affiliation><nlm:affiliation>Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Scelo, Ghislaine" sort="Scelo, Ghislaine" uniqKey="Scelo G" first="Ghislaine" last="Scelo">Ghislaine Scelo</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Carreras Torres, Robert" sort="Carreras Torres, Robert" uniqKey="Carreras Torres R" first="Robert" last="Carreras-Torres">Robert Carreras-Torres</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gaborieau, Valerie" sort="Gaborieau, Valerie" uniqKey="Gaborieau V" first="Valerie" last="Gaborieau">Valerie Gaborieau</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M" last="Bracci">Paige M. Bracci</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, University of California San Francisco.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Neale, Rachel E" sort="Neale, Rachel E" uniqKey="Neale R" first="Rachel E" last="Neale">Rachel E. Neale</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Olson, Sara H" sort="Olson, Sara H" uniqKey="Olson S" first="Sara H" last="Olson">Sara H. Olson</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gallinger, Steven" sort="Gallinger, Steven" uniqKey="Gallinger S" first="Steven" last="Gallinger">Steven Gallinger</name>
<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Li, Donghui" sort="Li, Donghui" uniqKey="Li D" first="Donghui" last="Li">Donghui Li</name>
<affiliation><nlm:affiliation>Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Petersen, Gloria M" sort="Petersen, Gloria M" uniqKey="Petersen G" first="Gloria M" last="Petersen">Gloria M. Petersen</name>
<affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Risch, Harvey A" sort="Risch, Harvey A" uniqKey="Risch H" first="Harvey A" last="Risch">Harvey A. Risch</name>
<affiliation><nlm:affiliation>Yale School of Public Health, Yale School of Medicine, and Yale Cancer Center, New Haven, Connecticut.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Klein, Alison P" sort="Klein, Alison P" uniqKey="Klein A" first="Alison P" last="Klein">Alison P. Klein</name>
<affiliation><nlm:affiliation>Departments of Oncology, Pathology and Epidemiology, Johns Hopkins School of Medicine, Baltimore, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Han, Jiali" sort="Han, Jiali" uniqKey="Han J" first="Jiali" last="Han">Jiali Han</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Fairbanks School of Public Health, Indiana University, Indianapolis57Indiana University Melvin and Bren Simon Cancer Center, Indianapolis.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Abnet, Christian C" sort="Abnet, Christian C" uniqKey="Abnet C" first="Christian C" last="Abnet">Christian C. Abnet</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Freedman, Neal D" sort="Freedman, Neal D" uniqKey="Freedman N" first="Neal D" last="Freedman">Neal D. Freedman</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Taylor, Philip R" sort="Taylor, Philip R" uniqKey="Taylor P" first="Philip R" last="Taylor">Philip R. Taylor</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Maris, John M" sort="Maris, John M" uniqKey="Maris J" first="John M" last="Maris">John M. Maris</name>
<affiliation><nlm:affiliation>Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Aben, Katja K" sort="Aben, Katja K" uniqKey="Aben K" first="Katja K" last="Aben">Katja K. Aben</name>
<affiliation><nlm:affiliation>Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands61Netherlands Comprehensive Cancer Organization, Utrecht, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kiemeney, Lambertus A" sort="Kiemeney, Lambertus A" uniqKey="Kiemeney L" first="Lambertus A" last="Kiemeney">Lambertus A. Kiemeney</name>
<affiliation><nlm:affiliation>Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vermeulen, Sita H" sort="Vermeulen, Sita H" uniqKey="Vermeulen S" first="Sita H" last="Vermeulen">Sita H. Vermeulen</name>
<affiliation><nlm:affiliation>Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wiencke, John K" sort="Wiencke, John K" uniqKey="Wiencke J" first="John K" last="Wiencke">John K. Wiencke</name>
<affiliation><nlm:affiliation>Department of Neurological Surgery, University of California, San Francisco, San Francisco, California63Institute of Human Genetics, University of California, San Francisco, San Francisco, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Walsh, Kyle M" sort="Walsh, Kyle M" uniqKey="Walsh K" first="Kyle M" last="Walsh">Kyle M. Walsh</name>
<affiliation><nlm:affiliation>Department of Neurological Surgery, University of California, San Francisco, San Francisco, California63Institute of Human Genetics, University of California, San Francisco, San Francisco, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wrensch, Margaret" sort="Wrensch, Margaret" uniqKey="Wrensch M" first="Margaret" last="Wrensch">Margaret Wrensch</name>
<affiliation><nlm:affiliation>Department of Neurological Surgery, University of California, San Francisco, San Francisco, California63Institute of Human Genetics, University of California, San Francisco, San Francisco, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rice, Terri" sort="Rice, Terri" uniqKey="Rice T" first="Terri" last="Rice">Terri Rice</name>
<affiliation><nlm:affiliation>Department of Neurological Surgery, University of California, San Francisco, San Francisco, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Turnbull, Clare" sort="Turnbull, Clare" uniqKey="Turnbull C" first="Clare" last="Turnbull">Clare Turnbull</name>
<affiliation><nlm:affiliation>The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, England64William Harvey Research Institute, Queen Mary University, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Litchfield, Kevin" sort="Litchfield, Kevin" uniqKey="Litchfield K" first="Kevin" last="Litchfield">Kevin Litchfield</name>
<affiliation><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Standl, Marie" sort="Standl, Marie" uniqKey="Standl M" first="Marie" last="Standl">Marie Standl</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Gonçalo R" last="Abecasis">Gonçalo R. Abecasis</name>
<affiliation><nlm:affiliation>Department of Biostatistics, University of Michigan, Ann Arbor.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sangiovanni, John Paul" sort="Sangiovanni, John Paul" uniqKey="Sangiovanni J" first="John Paul" last="Sangiovanni">John Paul Sangiovanni</name>
<affiliation><nlm:affiliation>National Institute of Alcohol Abuse and Alcoholism, Laboratory of Membrane Biophysics and Biochemistry, Section on Nutritional Neuroscience, Bethesda, Maryland69Department of Biochemistry and Molecular and Cellular Biology, Georgetown School of Medicine, Washington, DC.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name>
<affiliation><nlm:affiliation>Division of Genetic Epidemiology, Institute for Medical Biometry and Statistics, Faculty of Medicine, and Medical Centre, University of Freiburg, Freiburg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mijatovic, Vladan" sort="Mijatovic, Vladan" uniqKey="Mijatovic V" first="Vladan" last="Mijatovic">Vladan Mijatovic</name>
<affiliation><nlm:affiliation>Department of Life and Reproduction Sciences, University of Verona, Verona, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sapkota, Yadav" sort="Sapkota, Yadav" uniqKey="Sapkota Y" first="Yadav" last="Sapkota">Yadav Sapkota</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Low, Siew Kee" sort="Low, Siew Kee" uniqKey="Low S" first="Siew-Kee" last="Low">Siew-Kee Low</name>
<affiliation><nlm:affiliation>Laboratory of Statistical Analysis, Centre for Integrative Medical Sciences, The Institute of Physical and Chemical Research (RIKEN), Yokohama, Japan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zondervan, Krina T" sort="Zondervan, Krina T" uniqKey="Zondervan K" first="Krina T" last="Zondervan">Krina T. Zondervan</name>
<affiliation><nlm:affiliation>Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, England74Nuffield Department of Obstetrics and Gynecology, University of Oxford, John Radcliffe Hospital, Oxford, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Nyholt, Dale R" sort="Nyholt, Dale R" uniqKey="Nyholt D" first="Dale R" last="Nyholt">Dale R. Nyholt</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia75Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Heel, David A" sort="Van Heel, David A" uniqKey="Van Heel D" first="David A" last="Van Heel">David A. Van Heel</name>
<affiliation><nlm:affiliation>Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hunt, Karen" sort="Hunt, Karen" uniqKey="Hunt K" first="Karen" last="Hunt">Karen Hunt</name>
<affiliation><nlm:affiliation>Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Arking, Dan E" sort="Arking, Dan E" uniqKey="Arking D" first="Dan E" last="Arking">Dan E. Arking</name>
<affiliation><nlm:affiliation>McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ashar, Foram N" sort="Ashar, Foram N" uniqKey="Ashar F" first="Foram N" last="Ashar">Foram N. Ashar</name>
<affiliation><nlm:affiliation>McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sotoodehnia, Nona" sort="Sotoodehnia, Nona" uniqKey="Sotoodehnia N" first="Nona" last="Sotoodehnia">Nona Sotoodehnia</name>
<affiliation><nlm:affiliation>Division of Cardiology and Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Woo, Daniel" sort="Woo, Daniel" uniqKey="Woo D" first="Daniel" last="Woo">Daniel Woo</name>
<affiliation><nlm:affiliation>University of Cincinnati College of Medicine, Department of Neurology, Cincinnati, Ohio.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rosand, Jonathan" sort="Rosand, Jonathan" uniqKey="Rosand J" first="Jonathan" last="Rosand">Jonathan Rosand</name>
<affiliation><nlm:affiliation>Massachusetts General Hospital, Neurology, Center for Human Genetic Research, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Comeau, Mary E" sort="Comeau, Mary E" uniqKey="Comeau M" first="Mary E" last="Comeau">Mary E. Comeau</name>
<affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Brown, W Mark" sort="Brown, W Mark" uniqKey="Brown W" first="W Mark" last="Brown">W Mark Brown</name>
<affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Silverman, Edwin K" sort="Silverman, Edwin K" uniqKey="Silverman E" first="Edwin K" last="Silverman">Edwin K. Silverman</name>
<affiliation><nlm:affiliation>Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hokanson, John E" sort="Hokanson, John E" uniqKey="Hokanson J" first="John E" last="Hokanson">John E. Hokanson</name>
<affiliation><nlm:affiliation>Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cho, Michael H" sort="Cho, Michael H" uniqKey="Cho M" first="Michael H" last="Cho">Michael H. Cho</name>
<affiliation><nlm:affiliation>Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name>
<affiliation><nlm:affiliation>Busselton Population Medical Research Institute Inc, Sir Charles Gairdner Hospital, Perth, Australia85PathWest Laboratory Medicine of Western Australia, Perth, Australia86School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Australia87School of Population Health, University of WA, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ferreira, Manuel A" sort="Ferreira, Manuel A" uniqKey="Ferreira M" first="Manuel A" last="Ferreira">Manuel A. Ferreira</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Thompson, Philip J" sort="Thompson, Philip J" uniqKey="Thompson P" first="Philip J" last="Thompson">Philip J. Thompson</name>
<affiliation><nlm:affiliation>The Lung Health Clinic and Institute for Respiratory Health, University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center at Houston, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F" last="Felix">Janine F. Felix</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name>
<affiliation><nlm:affiliation>Department of Epidemiology, University of Washington, Seattle.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Christiano, Angela M" sort="Christiano, Angela M" uniqKey="Christiano A" first="Angela M" last="Christiano">Angela M. Christiano</name>
<affiliation><nlm:affiliation>Departments of Dermatology and Genetics & Development, Columbia University, New York, New York.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Petukhova, Lynn" sort="Petukhova, Lynn" uniqKey="Petukhova L" first="Lynn" last="Petukhova">Lynn Petukhova</name>
<affiliation><nlm:affiliation>Departments of Dermatology and Epidemiology, Columbia University, New York, New York.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Betz, Regina C" sort="Betz, Regina C" uniqKey="Betz R" first="Regina C" last="Betz">Regina C. Betz</name>
<affiliation><nlm:affiliation>Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fan, Xing" sort="Fan, Xing" uniqKey="Fan X" first="Xing" last="Fan">Xing Fan</name>
<affiliation><nlm:affiliation>Institute of Dermatology & Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zhang, Xuejun" sort="Zhang, Xuejun" uniqKey="Zhang X" first="Xuejun" last="Zhang">Xuejun Zhang</name>
<affiliation><nlm:affiliation>Institute of Dermatology & Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zhu, Caihong" sort="Zhu, Caihong" uniqKey="Zhu C" first="Caihong" last="Zhu">Caihong Zhu</name>
<affiliation><nlm:affiliation>Institute of Dermatology & Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Langefeld, Carl D" sort="Langefeld, Carl D" uniqKey="Langefeld C" first="Carl D" last="Langefeld">Carl D. Langefeld</name>
<affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Thompson, Susan D" sort="Thompson, Susan D" uniqKey="Thompson S" first="Susan D" last="Thompson">Susan D. Thompson</name>
<affiliation><nlm:affiliation>Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wang, Feijie" sort="Wang, Feijie" uniqKey="Wang F" first="Feijie" last="Wang">Feijie Wang</name>
<affiliation><nlm:affiliation>Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lin, Xu" sort="Lin, Xu" uniqKey="Lin X" first="Xu" last="Lin">Xu Lin</name>
<affiliation><nlm:affiliation>Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schwartz, David A" sort="Schwartz, David A" uniqKey="Schwartz D" first="David A" last="Schwartz">David A. Schwartz</name>
<affiliation><nlm:affiliation>Department of Medicine, School of Medicine, University of Colorado, Aurora.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fingerlin, Tasha" sort="Fingerlin, Tasha" uniqKey="Fingerlin T" first="Tasha" last="Fingerlin">Tasha Fingerlin</name>
<affiliation><nlm:affiliation>Department of Biomedical Research, National Jewish Health Hospital, Denver, Colorado.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name>
<affiliation><nlm:affiliation>Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California101Departments of Pediatrics and Medicine, Harbor-UCLA Medical Center, Torrance, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cotch, Mary Frances" sort="Cotch, Mary Frances" uniqKey="Cotch M" first="Mary Frances" last="Cotch">Mary Frances Cotch</name>
<affiliation><nlm:affiliation>Epidemiology Branch, Division of Epidemiology and Clinical Applications, Intramural Research Program, National Eye Institute, National Institutes of Health, Clinical Research Center, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jensen, Richard A" sort="Jensen, Richard A" uniqKey="Jensen R" first="Richard A" last="Jensen">Richard A. Jensen</name>
<affiliation><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle104Department of Medicine, University of Washington, Seattle.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Munz, Matthias" sort="Munz, Matthias" uniqKey="Munz M" first="Matthias" last="Munz">Matthias Munz</name>
<affiliation><nlm:affiliation>Department of Periodontology and Synoptic Dentistry, Center for Dental and Craniofacial Sciences, Charité - University Medicine Berlin, Berlin, Germany106Institute for Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Dommisch, Henrik" sort="Dommisch, Henrik" uniqKey="Dommisch H" first="Henrik" last="Dommisch">Henrik Dommisch</name>
<affiliation><nlm:affiliation>Department of Periodontology and Synoptic Dentistry, Center for Dental and Craniofacial Sciences, Charité - University Medicine Berlin, Berlin, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schaefer, Arne S" sort="Schaefer, Arne S" uniqKey="Schaefer A" first="Arne S" last="Schaefer">Arne S. Schaefer</name>
<affiliation><nlm:affiliation>Department of Periodontology and Synoptic Dentistry, Center for Dental and Craniofacial Sciences, Charité - University Medicine Berlin, Berlin, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Han, Fang" sort="Han, Fang" uniqKey="Han F" first="Fang" last="Han">Fang Han</name>
<affiliation><nlm:affiliation>Department of Pulmonary Medicine, Peking University People's Hospital, Beijing, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ollila, Hanna M" sort="Ollila, Hanna M" uniqKey="Ollila H" first="Hanna M" last="Ollila">Hanna M. Ollila</name>
<affiliation><nlm:affiliation>Stanford University, Center for Sleep Sciences, Palo Alto, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hillary, Ryan P" sort="Hillary, Ryan P" uniqKey="Hillary R" first="Ryan P" last="Hillary">Ryan P. Hillary</name>
<affiliation><nlm:affiliation>Stanford University, Center for Sleep Sciences, Palo Alto, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Albagha, Omar" sort="Albagha, Omar" uniqKey="Albagha O" first="Omar" last="Albagha">Omar Albagha</name>
<affiliation><nlm:affiliation>Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Doha, Qatar110Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ralston, Stuart H" sort="Ralston, Stuart H" uniqKey="Ralston S" first="Stuart H" last="Ralston">Stuart H. Ralston</name>
<affiliation><nlm:affiliation>Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zeng, Chenjie" sort="Zeng, Chenjie" uniqKey="Zeng C" first="Chenjie" last="Zeng">Chenjie Zeng</name>
<affiliation><nlm:affiliation>Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name>
<affiliation><nlm:affiliation>Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name>
<affiliation><nlm:affiliation>Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Reis, Andre" sort="Reis, Andre" uniqKey="Reis A" first="Andre" last="Reis">Andre Reis</name>
<affiliation><nlm:affiliation>Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Uebe, Steffen" sort="Uebe, Steffen" uniqKey="Uebe S" first="Steffen" last="Uebe">Steffen Uebe</name>
<affiliation><nlm:affiliation>Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan115Graduate School of Clinical Psychology, Teikyo Heisei University Major of Professional Clinical Psychology, Tokyo, Japan.</nlm:affiliation>
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<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada119Departments of Medicine, Immunology, Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
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<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada119Departments of Medicine, Immunology, Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
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<affiliation><nlm:affiliation>Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</nlm:affiliation>
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<affiliation><nlm:affiliation>Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China121Peking Union Medical College, Beijing, China.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Biology, University of Pisa, Pisa, Italy.</nlm:affiliation>
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<affiliation><nlm:affiliation>University Hospital Schleswig-Holstein, Kiel, Germany.</nlm:affiliation>
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<affiliation><nlm:affiliation>University Hospital Schleswig-Holstein, Kiel, Germany126Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.</nlm:affiliation>
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<affiliation><nlm:affiliation>Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.</nlm:affiliation>
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<affiliation><nlm:affiliation>Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Tenerife, Spain128CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Biostatistics, University of Washington, Seattle.</nlm:affiliation>
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<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England158University of Bristol/University Hospitals Bristol NHS Foundation Trust National Institute for Health Research Bristol Nutrition Biomedical Research Unit, Bristol, England.</nlm:affiliation>
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<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
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</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:28241208</idno>
<idno type="pmid">28241208</idno>
<idno type="doi">10.1001/jamaoncol.2016.5945</idno>
<idno type="wicri:Area/PubMed/Corpus">000D22</idno>
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</publicationStmt>
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<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England4University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge, England5Department of Neurology, Innsbruck Medical University, Austria.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London England8NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, England.</nlm:affiliation>
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</author>
<author><name sortKey="Kurian, Kathreena M" sort="Kurian, Kathreena M" uniqKey="Kurian K" first="Kathreena M" last="Kurian">Kathreena M. Kurian</name>
<affiliation><nlm:affiliation>Brain Tumour Research Group, Institute of Clinical Neuroscience, Learning and Research Building, Southmead Hospital, University of Bristol.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pooley, Karen A" sort="Pooley, Karen A" uniqKey="Pooley K" first="Karen A" last="Pooley">Karen A. Pooley</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Eeles, Rosalind A" sort="Eeles, Rosalind A" uniqKey="Eeles R" first="Rosalind A" last="Eeles">Rosalind A. Eeles</name>
<affiliation><nlm:affiliation>The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lee, Jeffrey E" sort="Lee, Jeffrey E" uniqKey="Lee J" first="Jeffrey E" last="Lee">Jeffrey E. Lee</name>
<affiliation><nlm:affiliation>Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fang, Shenying" sort="Fang, Shenying" uniqKey="Fang S" first="Shenying" last="Fang">Shenying Fang</name>
<affiliation><nlm:affiliation>Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chen, Wei V" sort="Chen, Wei V" uniqKey="Chen W" first="Wei V" last="Chen">Wei V. Chen</name>
<affiliation><nlm:affiliation>Department of Clinical Applications & Support, The University of Texas MD Anderson Cancer Center, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Law, Matthew H" sort="Law, Matthew H" uniqKey="Law M" first="Matthew H" last="Law">Matthew H. Law</name>
<affiliation><nlm:affiliation>Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bowdler, Lisa M" sort="Bowdler, Lisa M" uniqKey="Bowdler L" first="Lisa M" last="Bowdler">Lisa M. Bowdler</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Iles, Mark M" sort="Iles, Mark M" uniqKey="Iles M" first="Mark M" last="Iles">Mark M. Iles</name>
<affiliation><nlm:affiliation>Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Yang, Qiong" sort="Yang, Qiong" uniqKey="Yang Q" first="Qiong" last="Yang">Qiong Yang</name>
<affiliation><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Worrall, Bradford B" sort="Worrall, Bradford B" uniqKey="Worrall B" first="Bradford B" last="Worrall">Bradford B. Worrall</name>
<affiliation><nlm:affiliation>Departments of Neurology and Public Health Sciences, University of Virginia Charlottesville, Virginia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Markus, Hugh Stephen" sort="Markus, Hugh Stephen" uniqKey="Markus H" first="Hugh Stephen" last="Markus">Hugh Stephen Markus</name>
<affiliation><nlm:affiliation>Department of Clinical Neurosciences, University of Cambridge, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hung, Rayjean J" sort="Hung, Rayjean J" uniqKey="Hung R" first="Rayjean J" last="Hung">Rayjean J. Hung</name>
<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada21Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Amos, Chris I" sort="Amos, Chris I" uniqKey="Amos C" first="Chris I" last="Amos">Chris I. Amos</name>
<affiliation><nlm:affiliation>Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B" last="Spurdle">Amanda B. Spurdle</name>
<affiliation><nlm:affiliation>Genetics and Computational Biology Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Thompson, Deborah J" sort="Thompson, Deborah J" uniqKey="Thompson D" first="Deborah J" last="Thompson">Deborah J. Thompson</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="O Mara, Tracy A" sort="O Mara, Tracy A" uniqKey="O Mara T" first="Tracy A" last="O'Mara">Tracy A. O'Mara</name>
<affiliation><nlm:affiliation>Genetics and Computational Biology Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wolpin, Brian" sort="Wolpin, Brian" uniqKey="Wolpin B" first="Brian" last="Wolpin">Brian Wolpin</name>
<affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Amundadottir, Laufey" sort="Amundadottir, Laufey" uniqKey="Amundadottir L" first="Laufey" last="Amundadottir">Laufey Amundadottir</name>
<affiliation><nlm:affiliation>Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Stolzenberg Solomon, Rachael" sort="Stolzenberg Solomon, Rachael" uniqKey="Stolzenberg Solomon R" first="Rachael" last="Stolzenberg-Solomon">Rachael Stolzenberg-Solomon</name>
<affiliation><nlm:affiliation>Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name>
<affiliation><nlm:affiliation>Hellenic Health Foundation, Athens, Greece28WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lund, Eiliv" sort="Lund, Eiliv" uniqKey="Lund E" first="Eiliv" last="Lund">Eiliv Lund</name>
<affiliation><nlm:affiliation>Institute of Community Medicine, UiT The Arctic University of Norway, Tromso, Norway.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Duell, Eric J" sort="Duell, Eric J" uniqKey="Duell E" first="Eric J" last="Duell">Eric J. Duell</name>
<affiliation><nlm:affiliation>Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Canzian, Federico" sort="Canzian, Federico" uniqKey="Canzian F" first="Federico" last="Canzian">Federico Canzian</name>
<affiliation><nlm:affiliation>Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name>
<affiliation><nlm:affiliation>Université Paris-Saclay, Université Paris-Sud, UVSQ, CESP, INSERM, Villejuif, France34Institut Gustave Roussy, Villejuif, France35Human Genetics Foundation (HuGeF), Torino, Italy36Cancer Council Victoria and University of Melbourne, Melbourne, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name>
<affiliation><nlm:affiliation>Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J" last="Gunter">Marc J. Gunter</name>
<affiliation><nlm:affiliation>School of Public Health, Imperial College London, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name>
<affiliation><nlm:affiliation>Cancer Registry, Azienda Ospedaliera "Civile M.P. Arezzo," Ragusa, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Svenson, Ulrika" sort="Svenson, Ulrika" uniqKey="Svenson U" first="Ulrika" last="Svenson">Ulrika Svenson</name>
<affiliation><nlm:affiliation>Department of Medical Biosciences, Umea University, Umea, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Rij, Andre" sort="Van Rij, Andre" uniqKey="Van Rij A" first="Andre" last="Van Rij">Andre Van Rij</name>
<affiliation><nlm:affiliation>Surgery Department, University of Otago, Dunedin, New Zealand.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Baas, Annette F" sort="Baas, Annette F" uniqKey="Baas A" first="Annette F" last="Baas">Annette F. Baas</name>
<affiliation><nlm:affiliation>Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bown, Matthew J" sort="Bown, Matthew J" uniqKey="Bown M" first="Matthew J" last="Bown">Matthew J. Bown</name>
<affiliation><nlm:affiliation>Department of Cardiovascular Sciences and the NIHR Leicester, Cardiovascular Biomedical Research Unit, University of Leicester, Glenfield Hospital, Leicester, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J" last="Samani">Nilesh J. Samani</name>
<affiliation><nlm:affiliation>Department of Cardiovascular Sciences and the NIHR Leicester, Cardiovascular Biomedical Research Unit, University of Leicester, Glenfield Hospital, Leicester, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van T Hof, Femke N G" sort="Van T Hof, Femke N G" uniqKey="Van T Hof F" first="Femke N G" last="Van T'Hof">Femke N G. Van T'Hof</name>
<affiliation><nlm:affiliation>Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tromp, Gerard" sort="Tromp, Gerard" uniqKey="Tromp G" first="Gerard" last="Tromp">Gerard Tromp</name>
<affiliation><nlm:affiliation>Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa46The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jones, Gregory T" sort="Jones, Gregory T" uniqKey="Jones G" first="Gregory T" last="Jones">Gregory T. Jones</name>
<affiliation><nlm:affiliation>Surgery Department, University of Otago, Dunedin, New Zealand.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kuivaniemi, Helena" sort="Kuivaniemi, Helena" uniqKey="Kuivaniemi H" first="Helena" last="Kuivaniemi">Helena Kuivaniemi</name>
<affiliation><nlm:affiliation>Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa46The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, Pennsylvania.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Elmore, James R" sort="Elmore, James R" uniqKey="Elmore J" first="James R" last="Elmore">James R. Elmore</name>
<affiliation><nlm:affiliation>Department of Vascular and Endovascular Surgery, Geisinger Health System, Danville, Pennsylvania.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Johansson, Mattias" sort="Johansson, Mattias" uniqKey="Johansson M" first="Mattias" last="Johansson">Mattias Johansson</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mckay, James" sort="Mckay, James" uniqKey="Mckay J" first="James" last="Mckay">James Mckay</name>
<affiliation><nlm:affiliation>Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Scelo, Ghislaine" sort="Scelo, Ghislaine" uniqKey="Scelo G" first="Ghislaine" last="Scelo">Ghislaine Scelo</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Carreras Torres, Robert" sort="Carreras Torres, Robert" uniqKey="Carreras Torres R" first="Robert" last="Carreras-Torres">Robert Carreras-Torres</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gaborieau, Valerie" sort="Gaborieau, Valerie" uniqKey="Gaborieau V" first="Valerie" last="Gaborieau">Valerie Gaborieau</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name>
<affiliation><nlm:affiliation>Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M" last="Bracci">Paige M. Bracci</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, University of California San Francisco.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Neale, Rachel E" sort="Neale, Rachel E" uniqKey="Neale R" first="Rachel E" last="Neale">Rachel E. Neale</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Olson, Sara H" sort="Olson, Sara H" uniqKey="Olson S" first="Sara H" last="Olson">Sara H. Olson</name>
<affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gallinger, Steven" sort="Gallinger, Steven" uniqKey="Gallinger S" first="Steven" last="Gallinger">Steven Gallinger</name>
<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Li, Donghui" sort="Li, Donghui" uniqKey="Li D" first="Donghui" last="Li">Donghui Li</name>
<affiliation><nlm:affiliation>Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Petersen, Gloria M" sort="Petersen, Gloria M" uniqKey="Petersen G" first="Gloria M" last="Petersen">Gloria M. Petersen</name>
<affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Risch, Harvey A" sort="Risch, Harvey A" uniqKey="Risch H" first="Harvey A" last="Risch">Harvey A. Risch</name>
<affiliation><nlm:affiliation>Yale School of Public Health, Yale School of Medicine, and Yale Cancer Center, New Haven, Connecticut.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Klein, Alison P" sort="Klein, Alison P" uniqKey="Klein A" first="Alison P" last="Klein">Alison P. Klein</name>
<affiliation><nlm:affiliation>Departments of Oncology, Pathology and Epidemiology, Johns Hopkins School of Medicine, Baltimore, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Han, Jiali" sort="Han, Jiali" uniqKey="Han J" first="Jiali" last="Han">Jiali Han</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Fairbanks School of Public Health, Indiana University, Indianapolis57Indiana University Melvin and Bren Simon Cancer Center, Indianapolis.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Abnet, Christian C" sort="Abnet, Christian C" uniqKey="Abnet C" first="Christian C" last="Abnet">Christian C. Abnet</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Freedman, Neal D" sort="Freedman, Neal D" uniqKey="Freedman N" first="Neal D" last="Freedman">Neal D. Freedman</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Taylor, Philip R" sort="Taylor, Philip R" uniqKey="Taylor P" first="Philip R" last="Taylor">Philip R. Taylor</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Maris, John M" sort="Maris, John M" uniqKey="Maris J" first="John M" last="Maris">John M. Maris</name>
<affiliation><nlm:affiliation>Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Aben, Katja K" sort="Aben, Katja K" uniqKey="Aben K" first="Katja K" last="Aben">Katja K. Aben</name>
<affiliation><nlm:affiliation>Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands61Netherlands Comprehensive Cancer Organization, Utrecht, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kiemeney, Lambertus A" sort="Kiemeney, Lambertus A" uniqKey="Kiemeney L" first="Lambertus A" last="Kiemeney">Lambertus A. Kiemeney</name>
<affiliation><nlm:affiliation>Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vermeulen, Sita H" sort="Vermeulen, Sita H" uniqKey="Vermeulen S" first="Sita H" last="Vermeulen">Sita H. Vermeulen</name>
<affiliation><nlm:affiliation>Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wiencke, John K" sort="Wiencke, John K" uniqKey="Wiencke J" first="John K" last="Wiencke">John K. Wiencke</name>
<affiliation><nlm:affiliation>Department of Neurological Surgery, University of California, San Francisco, San Francisco, California63Institute of Human Genetics, University of California, San Francisco, San Francisco, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Walsh, Kyle M" sort="Walsh, Kyle M" uniqKey="Walsh K" first="Kyle M" last="Walsh">Kyle M. Walsh</name>
<affiliation><nlm:affiliation>Department of Neurological Surgery, University of California, San Francisco, San Francisco, California63Institute of Human Genetics, University of California, San Francisco, San Francisco, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wrensch, Margaret" sort="Wrensch, Margaret" uniqKey="Wrensch M" first="Margaret" last="Wrensch">Margaret Wrensch</name>
<affiliation><nlm:affiliation>Department of Neurological Surgery, University of California, San Francisco, San Francisco, California63Institute of Human Genetics, University of California, San Francisco, San Francisco, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rice, Terri" sort="Rice, Terri" uniqKey="Rice T" first="Terri" last="Rice">Terri Rice</name>
<affiliation><nlm:affiliation>Department of Neurological Surgery, University of California, San Francisco, San Francisco, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Turnbull, Clare" sort="Turnbull, Clare" uniqKey="Turnbull C" first="Clare" last="Turnbull">Clare Turnbull</name>
<affiliation><nlm:affiliation>The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, England64William Harvey Research Institute, Queen Mary University, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Litchfield, Kevin" sort="Litchfield, Kevin" uniqKey="Litchfield K" first="Kevin" last="Litchfield">Kevin Litchfield</name>
<affiliation><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Standl, Marie" sort="Standl, Marie" uniqKey="Standl M" first="Marie" last="Standl">Marie Standl</name>
<affiliation><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Gonçalo R" last="Abecasis">Gonçalo R. Abecasis</name>
<affiliation><nlm:affiliation>Department of Biostatistics, University of Michigan, Ann Arbor.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sangiovanni, John Paul" sort="Sangiovanni, John Paul" uniqKey="Sangiovanni J" first="John Paul" last="Sangiovanni">John Paul Sangiovanni</name>
<affiliation><nlm:affiliation>National Institute of Alcohol Abuse and Alcoholism, Laboratory of Membrane Biophysics and Biochemistry, Section on Nutritional Neuroscience, Bethesda, Maryland69Department of Biochemistry and Molecular and Cellular Biology, Georgetown School of Medicine, Washington, DC.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name>
<affiliation><nlm:affiliation>Division of Genetic Epidemiology, Institute for Medical Biometry and Statistics, Faculty of Medicine, and Medical Centre, University of Freiburg, Freiburg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mijatovic, Vladan" sort="Mijatovic, Vladan" uniqKey="Mijatovic V" first="Vladan" last="Mijatovic">Vladan Mijatovic</name>
<affiliation><nlm:affiliation>Department of Life and Reproduction Sciences, University of Verona, Verona, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sapkota, Yadav" sort="Sapkota, Yadav" uniqKey="Sapkota Y" first="Yadav" last="Sapkota">Yadav Sapkota</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Low, Siew Kee" sort="Low, Siew Kee" uniqKey="Low S" first="Siew-Kee" last="Low">Siew-Kee Low</name>
<affiliation><nlm:affiliation>Laboratory of Statistical Analysis, Centre for Integrative Medical Sciences, The Institute of Physical and Chemical Research (RIKEN), Yokohama, Japan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zondervan, Krina T" sort="Zondervan, Krina T" uniqKey="Zondervan K" first="Krina T" last="Zondervan">Krina T. Zondervan</name>
<affiliation><nlm:affiliation>Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, England74Nuffield Department of Obstetrics and Gynecology, University of Oxford, John Radcliffe Hospital, Oxford, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W" last="Montgomery">Grant W. Montgomery</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Nyholt, Dale R" sort="Nyholt, Dale R" uniqKey="Nyholt D" first="Dale R" last="Nyholt">Dale R. Nyholt</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia75Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Heel, David A" sort="Van Heel, David A" uniqKey="Van Heel D" first="David A" last="Van Heel">David A. Van Heel</name>
<affiliation><nlm:affiliation>Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hunt, Karen" sort="Hunt, Karen" uniqKey="Hunt K" first="Karen" last="Hunt">Karen Hunt</name>
<affiliation><nlm:affiliation>Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Arking, Dan E" sort="Arking, Dan E" uniqKey="Arking D" first="Dan E" last="Arking">Dan E. Arking</name>
<affiliation><nlm:affiliation>McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ashar, Foram N" sort="Ashar, Foram N" uniqKey="Ashar F" first="Foram N" last="Ashar">Foram N. Ashar</name>
<affiliation><nlm:affiliation>McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sotoodehnia, Nona" sort="Sotoodehnia, Nona" uniqKey="Sotoodehnia N" first="Nona" last="Sotoodehnia">Nona Sotoodehnia</name>
<affiliation><nlm:affiliation>Division of Cardiology and Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Woo, Daniel" sort="Woo, Daniel" uniqKey="Woo D" first="Daniel" last="Woo">Daniel Woo</name>
<affiliation><nlm:affiliation>University of Cincinnati College of Medicine, Department of Neurology, Cincinnati, Ohio.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rosand, Jonathan" sort="Rosand, Jonathan" uniqKey="Rosand J" first="Jonathan" last="Rosand">Jonathan Rosand</name>
<affiliation><nlm:affiliation>Massachusetts General Hospital, Neurology, Center for Human Genetic Research, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Comeau, Mary E" sort="Comeau, Mary E" uniqKey="Comeau M" first="Mary E" last="Comeau">Mary E. Comeau</name>
<affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Brown, W Mark" sort="Brown, W Mark" uniqKey="Brown W" first="W Mark" last="Brown">W Mark Brown</name>
<affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Silverman, Edwin K" sort="Silverman, Edwin K" uniqKey="Silverman E" first="Edwin K" last="Silverman">Edwin K. Silverman</name>
<affiliation><nlm:affiliation>Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hokanson, John E" sort="Hokanson, John E" uniqKey="Hokanson J" first="John E" last="Hokanson">John E. Hokanson</name>
<affiliation><nlm:affiliation>Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cho, Michael H" sort="Cho, Michael H" uniqKey="Cho M" first="Michael H" last="Cho">Michael H. Cho</name>
<affiliation><nlm:affiliation>Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name>
<affiliation><nlm:affiliation>Busselton Population Medical Research Institute Inc, Sir Charles Gairdner Hospital, Perth, Australia85PathWest Laboratory Medicine of Western Australia, Perth, Australia86School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Australia87School of Population Health, University of WA, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ferreira, Manuel A" sort="Ferreira, Manuel A" uniqKey="Ferreira M" first="Manuel A" last="Ferreira">Manuel A. Ferreira</name>
<affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Thompson, Philip J" sort="Thompson, Philip J" uniqKey="Thompson P" first="Philip J" last="Thompson">Philip J. Thompson</name>
<affiliation><nlm:affiliation>The Lung Health Clinic and Institute for Respiratory Health, University of Western Australia, Perth, Australia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center at Houston, Houston.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F" last="Felix">Janine F. Felix</name>
<affiliation><nlm:affiliation>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name>
<affiliation><nlm:affiliation>Department of Epidemiology, University of Washington, Seattle.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Christiano, Angela M" sort="Christiano, Angela M" uniqKey="Christiano A" first="Angela M" last="Christiano">Angela M. Christiano</name>
<affiliation><nlm:affiliation>Departments of Dermatology and Genetics & Development, Columbia University, New York, New York.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Petukhova, Lynn" sort="Petukhova, Lynn" uniqKey="Petukhova L" first="Lynn" last="Petukhova">Lynn Petukhova</name>
<affiliation><nlm:affiliation>Departments of Dermatology and Epidemiology, Columbia University, New York, New York.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Betz, Regina C" sort="Betz, Regina C" uniqKey="Betz R" first="Regina C" last="Betz">Regina C. Betz</name>
<affiliation><nlm:affiliation>Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fan, Xing" sort="Fan, Xing" uniqKey="Fan X" first="Xing" last="Fan">Xing Fan</name>
<affiliation><nlm:affiliation>Institute of Dermatology & Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zhang, Xuejun" sort="Zhang, Xuejun" uniqKey="Zhang X" first="Xuejun" last="Zhang">Xuejun Zhang</name>
<affiliation><nlm:affiliation>Institute of Dermatology & Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zhu, Caihong" sort="Zhu, Caihong" uniqKey="Zhu C" first="Caihong" last="Zhu">Caihong Zhu</name>
<affiliation><nlm:affiliation>Institute of Dermatology & Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Langefeld, Carl D" sort="Langefeld, Carl D" uniqKey="Langefeld C" first="Carl D" last="Langefeld">Carl D. Langefeld</name>
<affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Thompson, Susan D" sort="Thompson, Susan D" uniqKey="Thompson S" first="Susan D" last="Thompson">Susan D. Thompson</name>
<affiliation><nlm:affiliation>Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wang, Feijie" sort="Wang, Feijie" uniqKey="Wang F" first="Feijie" last="Wang">Feijie Wang</name>
<affiliation><nlm:affiliation>Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lin, Xu" sort="Lin, Xu" uniqKey="Lin X" first="Xu" last="Lin">Xu Lin</name>
<affiliation><nlm:affiliation>Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schwartz, David A" sort="Schwartz, David A" uniqKey="Schwartz D" first="David A" last="Schwartz">David A. Schwartz</name>
<affiliation><nlm:affiliation>Department of Medicine, School of Medicine, University of Colorado, Aurora.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fingerlin, Tasha" sort="Fingerlin, Tasha" uniqKey="Fingerlin T" first="Tasha" last="Fingerlin">Tasha Fingerlin</name>
<affiliation><nlm:affiliation>Department of Biomedical Research, National Jewish Health Hospital, Denver, Colorado.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name>
<affiliation><nlm:affiliation>Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California101Departments of Pediatrics and Medicine, Harbor-UCLA Medical Center, Torrance, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cotch, Mary Frances" sort="Cotch, Mary Frances" uniqKey="Cotch M" first="Mary Frances" last="Cotch">Mary Frances Cotch</name>
<affiliation><nlm:affiliation>Epidemiology Branch, Division of Epidemiology and Clinical Applications, Intramural Research Program, National Eye Institute, National Institutes of Health, Clinical Research Center, Bethesda, Maryland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jensen, Richard A" sort="Jensen, Richard A" uniqKey="Jensen R" first="Richard A" last="Jensen">Richard A. Jensen</name>
<affiliation><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle104Department of Medicine, University of Washington, Seattle.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Munz, Matthias" sort="Munz, Matthias" uniqKey="Munz M" first="Matthias" last="Munz">Matthias Munz</name>
<affiliation><nlm:affiliation>Department of Periodontology and Synoptic Dentistry, Center for Dental and Craniofacial Sciences, Charité - University Medicine Berlin, Berlin, Germany106Institute for Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Dommisch, Henrik" sort="Dommisch, Henrik" uniqKey="Dommisch H" first="Henrik" last="Dommisch">Henrik Dommisch</name>
<affiliation><nlm:affiliation>Department of Periodontology and Synoptic Dentistry, Center for Dental and Craniofacial Sciences, Charité - University Medicine Berlin, Berlin, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schaefer, Arne S" sort="Schaefer, Arne S" uniqKey="Schaefer A" first="Arne S" last="Schaefer">Arne S. Schaefer</name>
<affiliation><nlm:affiliation>Department of Periodontology and Synoptic Dentistry, Center for Dental and Craniofacial Sciences, Charité - University Medicine Berlin, Berlin, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Han, Fang" sort="Han, Fang" uniqKey="Han F" first="Fang" last="Han">Fang Han</name>
<affiliation><nlm:affiliation>Department of Pulmonary Medicine, Peking University People's Hospital, Beijing, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ollila, Hanna M" sort="Ollila, Hanna M" uniqKey="Ollila H" first="Hanna M" last="Ollila">Hanna M. Ollila</name>
<affiliation><nlm:affiliation>Stanford University, Center for Sleep Sciences, Palo Alto, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hillary, Ryan P" sort="Hillary, Ryan P" uniqKey="Hillary R" first="Ryan P" last="Hillary">Ryan P. Hillary</name>
<affiliation><nlm:affiliation>Stanford University, Center for Sleep Sciences, Palo Alto, California.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Albagha, Omar" sort="Albagha, Omar" uniqKey="Albagha O" first="Omar" last="Albagha">Omar Albagha</name>
<affiliation><nlm:affiliation>Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Doha, Qatar110Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ralston, Stuart H" sort="Ralston, Stuart H" uniqKey="Ralston S" first="Stuart H" last="Ralston">Stuart H. Ralston</name>
<affiliation><nlm:affiliation>Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zeng, Chenjie" sort="Zeng, Chenjie" uniqKey="Zeng C" first="Chenjie" last="Zeng">Chenjie Zeng</name>
<affiliation><nlm:affiliation>Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name>
<affiliation><nlm:affiliation>Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name>
<affiliation><nlm:affiliation>Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Reis, Andre" sort="Reis, Andre" uniqKey="Reis A" first="Andre" last="Reis">Andre Reis</name>
<affiliation><nlm:affiliation>Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Uebe, Steffen" sort="Uebe, Steffen" uniqKey="Uebe S" first="Steffen" last="Uebe">Steffen Uebe</name>
<affiliation><nlm:affiliation>Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Huffmeier, Ulrike" sort="Huffmeier, Ulrike" uniqKey="Huffmeier U" first="Ulrike" last="Hüffmeier">Ulrike Hüffmeier</name>
<affiliation><nlm:affiliation>Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kawamura, Yoshiya" sort="Kawamura, Yoshiya" uniqKey="Kawamura Y" first="Yoshiya" last="Kawamura">Yoshiya Kawamura</name>
<affiliation><nlm:affiliation>Department of Psychiatry, Shonan Kamakura General Hospital, Kanagawa, Japan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Otowa, Takeshi" sort="Otowa, Takeshi" uniqKey="Otowa T" first="Takeshi" last="Otowa">Takeshi Otowa</name>
<affiliation><nlm:affiliation>Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan115Graduate School of Clinical Psychology, Teikyo Heisei University Major of Professional Clinical Psychology, Tokyo, Japan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sasaki, Tsukasa" sort="Sasaki, Tsukasa" uniqKey="Sasaki T" first="Tsukasa" last="Sasaki">Tsukasa Sasaki</name>
<affiliation><nlm:affiliation>Department of Physical and Health Education, Graduate School of Education, University of Tokyo, Tokyo, Japan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hibberd, Martin Lloyd" sort="Hibberd, Martin Lloyd" uniqKey="Hibberd M" first="Martin Lloyd" last="Hibberd">Martin Lloyd Hibberd</name>
<affiliation><nlm:affiliation>Infectious Diseases, Genome Institute of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Davila, Sonia" sort="Davila, Sonia" uniqKey="Davila S" first="Sonia" last="Davila">Sonia Davila</name>
<affiliation><nlm:affiliation>Human Genetics, Genome Institute of Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Xie, Gang" sort="Xie, Gang" uniqKey="Xie G" first="Gang" last="Xie">Gang Xie</name>
<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada119Departments of Medicine, Immunology, Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Siminovitch, Katherine" sort="Siminovitch, Katherine" uniqKey="Siminovitch K" first="Katherine" last="Siminovitch">Katherine Siminovitch</name>
<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada119Departments of Medicine, Immunology, Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bei, Jin Xin" sort="Bei, Jin Xin" uniqKey="Bei J" first="Jin-Xin" last="Bei">Jin-Xin Bei</name>
<affiliation><nlm:affiliation>Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zeng, Yi Xin" sort="Zeng, Yi Xin" uniqKey="Zeng Y" first="Yi-Xin" last="Zeng">Yi-Xin Zeng</name>
<affiliation><nlm:affiliation>Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China121Peking Union Medical College, Beijing, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Forsti, Asta" sort="Forsti, Asta" uniqKey="Forsti A" first="Asta" last="Försti">Asta Försti</name>
<affiliation><nlm:affiliation>Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany123Center for Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chen, Bowang" sort="Chen, Bowang" uniqKey="Chen B" first="Bowang" last="Chen">Bowang Chen</name>
<affiliation><nlm:affiliation>Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Landi, Stefano" sort="Landi, Stefano" uniqKey="Landi S" first="Stefano" last="Landi">Stefano Landi</name>
<affiliation><nlm:affiliation>Department of Biology, University of Pisa, Pisa, Italy.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name>
<affiliation><nlm:affiliation>University Hospital Schleswig-Holstein, Kiel, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fischer, Annegret" sort="Fischer, Annegret" uniqKey="Fischer A" first="Annegret" last="Fischer">Annegret Fischer</name>
<affiliation><nlm:affiliation>University Hospital Schleswig-Holstein, Kiel, Germany126Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ellinghaus, David" sort="Ellinghaus, David" uniqKey="Ellinghaus D" first="David" last="Ellinghaus">David Ellinghaus</name>
<affiliation><nlm:affiliation>Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Flores, Carlos" sort="Flores, Carlos" uniqKey="Flores C" first="Carlos" last="Flores">Carlos Flores</name>
<affiliation><nlm:affiliation>Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Tenerife, Spain128CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Noth, Imre" sort="Noth, Imre" uniqKey="Noth I" first="Imre" last="Noth">Imre Noth</name>
<affiliation><nlm:affiliation>Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ma, Shwu Fan" sort="Ma, Shwu Fan" uniqKey="Ma S" first="Shwu-Fan" last="Ma">Shwu-Fan Ma</name>
<affiliation><nlm:affiliation>Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Foo, Jia Nee" sort="Foo, Jia Nee" uniqKey="Foo J" first="Jia Nee" last="Foo">Jia Nee Foo</name>
<affiliation><nlm:affiliation>Human Genetics, Genome Institute of Singapore, A*STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name>
<affiliation><nlm:affiliation>Human Genetics, Genome Institute of Singapore, A*STAR, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kim, Jong Won" sort="Kim, Jong Won" uniqKey="Kim J" first="Jong-Won" last="Kim">Jong-Won Kim</name>
<affiliation><nlm:affiliation>Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan, University School of Medicine, Gangnam-gu, Seoul, South Korea.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cox, David G" sort="Cox, David G" uniqKey="Cox D" first="David G" last="Cox">David G. Cox</name>
<affiliation><nlm:affiliation>Cancer Research Center of Lyon, INSERM U1052, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Delattre, Olivier" sort="Delattre, Olivier" uniqKey="Delattre O" first="Olivier" last="Delattre">Olivier Delattre</name>
<affiliation><nlm:affiliation>Inserm U830, Institut Curie, PSL University, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mirabeau, Olivier" sort="Mirabeau, Olivier" uniqKey="Mirabeau O" first="Olivier" last="Mirabeau">Olivier Mirabeau</name>
<affiliation><nlm:affiliation>Inserm U830, Institut Curie, PSL University, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Skibola, Christine F" sort="Skibola, Christine F" uniqKey="Skibola C" first="Christine F" last="Skibola">Christine F. Skibola</name>
<affiliation><nlm:affiliation>Department of Epidemiology, University of Alabama at Birmingham.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tang, Clara S" sort="Tang, Clara S" uniqKey="Tang C" first="Clara S" last="Tang">Clara S. Tang</name>
<affiliation><nlm:affiliation>Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Garcia Barcelo, Merce" sort="Garcia Barcelo, Merce" uniqKey="Garcia Barcelo M" first="Merce" last="Garcia-Barcelo">Merce Garcia-Barcelo</name>
<affiliation><nlm:affiliation>Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chang, Kai Ping" sort="Chang, Kai Ping" uniqKey="Chang K" first="Kai-Ping" last="Chang">Kai-Ping Chang</name>
<affiliation><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital at Lin-Kou, Taoyuan, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Su, Wen Hui" sort="Su, Wen Hui" uniqKey="Su W" first="Wen-Hui" last="Su">Wen-Hui Su</name>
<affiliation><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital at Lin-Kou, Taoyuan, Taiwan137Department of Biomedical Sciences, Graduate Institute of Biomedical Sciences, College of Medicine, Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chang, Yu Sun" sort="Chang, Yu Sun" uniqKey="Chang Y" first="Yu-Sun" last="Chang">Yu-Sun Chang</name>
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</author>
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</author>
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<author><name sortKey="Kubo, Michiaki" sort="Kubo, Michiaki" uniqKey="Kubo M" first="Michiaki" last="Kubo">Michiaki Kubo</name>
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<author><name sortKey="Cha, Pei Chieng" sort="Cha, Pei Chieng" uniqKey="Cha P" first="Pei-Chieng" last="Cha">Pei-Chieng Cha</name>
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</author>
<author><name sortKey="Nakamura, Yusuke" sort="Nakamura, Yusuke" uniqKey="Nakamura Y" first="Yusuke" last="Nakamura">Yusuke Nakamura</name>
<affiliation><nlm:affiliation>Center for Personalized Therapeutics, The University of Chicago, Chicago, Illinois.</nlm:affiliation>
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</author>
<author><name sortKey="Levy, Daniel" sort="Levy, Daniel" uniqKey="Levy D" first="Daniel" last="Levy">Daniel Levy</name>
<affiliation><nlm:affiliation>The NHLBI's Framingham Heart Study, Framingham, Massachusetts, Population Sciences Branch of the National Heart, Lung, and Blood Institute, Bethesda, Maryland.</nlm:affiliation>
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</author>
<author><name sortKey="Kimura, Masayuki" sort="Kimura, Masayuki" uniqKey="Kimura M" first="Masayuki" last="Kimura">Masayuki Kimura</name>
<affiliation><nlm:affiliation>Center of Human Development and Aging, Department of Pediatrics, New Jersey Medical School, Rutgers, The State University of New Jersey.</nlm:affiliation>
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</author>
<author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name>
<affiliation><nlm:affiliation>The NHLBI's Framingham Heart Study, Framingham, Massachusetts, Population Sciences Branch of the National Heart, Lung, and Blood Institute, Bethesda, Maryland.</nlm:affiliation>
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</author>
<author><name sortKey="Hunt, Steven" sort="Hunt, Steven" uniqKey="Hunt S" first="Steven" last="Hunt">Steven Hunt</name>
<affiliation><nlm:affiliation>Department of Genetic Medicine, Weill Cornell Medicine in Qatar, Doha, Qatar.</nlm:affiliation>
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</author>
<author><name sortKey="Spector, Tim" sort="Spector, Tim" uniqKey="Spector T" first="Tim" last="Spector">Tim Spector</name>
<affiliation><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London England.</nlm:affiliation>
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</author>
<author><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name>
<affiliation><nlm:affiliation>Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton Cambridge, England.</nlm:affiliation>
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</author>
<author><name sortKey="Manichaikul, Ani W" sort="Manichaikul, Ani W" uniqKey="Manichaikul A" first="Ani W" last="Manichaikul">Ani W. Manichaikul</name>
<affiliation><nlm:affiliation>Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville.</nlm:affiliation>
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</author>
<author><name sortKey="Barr, R Graham" sort="Barr, R Graham" uniqKey="Barr R" first="R Graham" last="Barr">R Graham Barr</name>
<affiliation><nlm:affiliation>Department of Medicine and Department of Epidemiology, Columbia University Medical Center, New York, New York.</nlm:affiliation>
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</author>
<author><name sortKey="Kahali, Bratati" sort="Kahali, Bratati" uniqKey="Kahali B" first="Bratati" last="Kahali">Bratati Kahali</name>
<affiliation><nlm:affiliation>Department of Internal Medicine, Division of Gastroenterology and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor.</nlm:affiliation>
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</author>
<author><name sortKey="Speliotes, Elizabeth" sort="Speliotes, Elizabeth" uniqKey="Speliotes E" first="Elizabeth" last="Speliotes">Elizabeth Speliotes</name>
<affiliation><nlm:affiliation>Department of Internal Medicine, Division of Gastroenterology and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor.</nlm:affiliation>
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<author><name sortKey="Yerges Armstrong, Laura M" sort="Yerges Armstrong, Laura M" uniqKey="Yerges Armstrong L" first="Laura M" last="Yerges-Armstrong">Laura M. Yerges-Armstrong</name>
<affiliation><nlm:affiliation>Department of Medicine, University of Maryland, Baltimore.</nlm:affiliation>
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</author>
<author><name sortKey="Cheng, Ching Yu" sort="Cheng, Ching Yu" uniqKey="Cheng C" first="Ching-Yu" last="Cheng">Ching-Yu Cheng</name>
<affiliation><nlm:affiliation>Singapore Eye Research Institute, Singapore National Eye Center, Singapore152Department of Ophthalmology, National University of Singapore and National University Health System, Singapore153Duke-NUS Medical School, Singapore.</nlm:affiliation>
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</author>
<author><name sortKey="Jonas, Jost B" sort="Jonas, Jost B" uniqKey="Jonas J" first="Jost B" last="Jonas">Jost B. Jonas</name>
<affiliation><nlm:affiliation>Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China155Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany.</nlm:affiliation>
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<author><name sortKey="Wong, Tien Yin" sort="Wong, Tien Yin" uniqKey="Wong T" first="Tien Yin" last="Wong">Tien Yin Wong</name>
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<affiliation><nlm:affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</nlm:affiliation>
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<author><name sortKey="Lin, Kuang" sort="Lin, Kuang" uniqKey="Lin K" first="Kuang" last="Lin">Kuang Lin</name>
<affiliation><nlm:affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</nlm:affiliation>
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<author><name sortKey="Powell, John F" sort="Powell, John F" uniqKey="Powell J" first="John F" last="Powell">John F. Powell</name>
<affiliation><nlm:affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</nlm:affiliation>
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</author>
<author><name sortKey="Rice, Kenneth" sort="Rice, Kenneth" uniqKey="Rice K" first="Kenneth" last="Rice">Kenneth Rice</name>
<affiliation><nlm:affiliation>Department of Biostatistics, University of Washington, Seattle.</nlm:affiliation>
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<author><name sortKey="Relton, Caroline L" sort="Relton, Caroline L" uniqKey="Relton C" first="Caroline L" last="Relton">Caroline L. Relton</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Martin, Richard M" sort="Martin, Richard M" uniqKey="Martin R" first="Richard M" last="Martin">Richard M. Martin</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England158University of Bristol/University Hospitals Bristol NHS Foundation Trust National Institute for Health Research Bristol Nutrition Biomedical Research Unit, Bristol, England.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Davey Smith, George" sort="Davey Smith, George" uniqKey="Davey Smith G" first="George" last="Davey Smith">George Davey Smith</name>
<affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">JAMA oncology</title>
<idno type="eISSN">2374-2445</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Cardiovascular Diseases (genetics)</term>
<term>Female</term>
<term>Genetic Predisposition to Disease (genetics)</term>
<term>Genome-Wide Association Study</term>
<term>Germ-Line Mutation</term>
<term>Humans</term>
<term>Male</term>
<term>Mendelian Randomization Analysis (methods)</term>
<term>Middle Aged</term>
<term>Neoplasms (genetics)</term>
<term>Polymorphism, Single Nucleotide</term>
<term>Risk Assessment (methods)</term>
<term>Telomere (genetics)</term>
<term>Telomere Homeostasis (genetics)</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Cardiovascular Diseases</term>
<term>Genetic Predisposition to Disease</term>
<term>Neoplasms</term>
<term>Telomere</term>
<term>Telomere Homeostasis</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Mendelian Randomization Analysis</term>
<term>Risk Assessment</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Genome-Wide Association Study</term>
<term>Germ-Line Mutation</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Polymorphism, Single Nucleotide</term>
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<front><div type="abstract" xml:lang="en">The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28241208</PMID>
<DateCreated><Year>2017</Year>
<Month>02</Month>
<Day>27</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>07</Month>
<Day>31</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>11</Month>
<Day>02</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">2374-2445</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>3</Volume>
<Issue>5</Issue>
<PubDate><Year>2017</Year>
<Month>May</Month>
<Day>01</Day>
</PubDate>
</JournalIssue>
<Title>JAMA oncology</Title>
<ISOAbbreviation>JAMA Oncol</ISOAbbreviation>
</Journal>
<ArticleTitle>Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.</ArticleTitle>
<Pagination><MedlinePgn>636-651</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1001/jamaoncol.2016.5945</ELocationID>
<Abstract><AbstractText Label="Importance" NlmCategory="UNASSIGNED">The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.</AbstractText>
<AbstractText Label="Objective" NlmCategory="UNASSIGNED">To conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases.</AbstractText>
<AbstractText Label="Data Sources" NlmCategory="UNASSIGNED">Genomewide association studies (GWAS) published up to January 15, 2015.</AbstractText>
<AbstractText Label="Study Selection" NlmCategory="UNASSIGNED">GWAS of noncommunicable diseases that assayed germline genetic variation and did not select cohort or control participants on the basis of preexisting diseases. Of 163 GWAS of noncommunicable diseases identified, summary data from 103 were available.</AbstractText>
<AbstractText Label="Data Extraction and Synthesis" NlmCategory="UNASSIGNED">Summary association statistics for single nucleotide polymorphisms (SNPs) that are strongly associated with telomere length in the general population.</AbstractText>
<AbstractText Label="Main Outcomes and Measures" NlmCategory="UNASSIGNED">Odds ratios (ORs) and 95% confidence intervals (CIs) for disease per standard deviation (SD) higher telomere length due to germline genetic variation.</AbstractText>
<AbstractText Label="Results" NlmCategory="UNASSIGNED">Summary data were available for 35 cancers and 48 non-neoplastic diseases, corresponding to 420 081 cases (median cases, 2526 per disease) and 1 093 105 controls (median, 6789 per disease). Increased telomere length due to germline genetic variation was generally associated with increased risk for site-specific cancers. The strongest associations (ORs [95% CIs] per 1-SD change in genetically increased telomere length) were observed for glioma, 5.27 (3.15-8.81); serous low-malignant-potential ovarian cancer, 4.35 (2.39-7.94); lung adenocarcinoma, 3.19 (2.40-4.22); neuroblastoma, 2.98 (1.92-4.62); bladder cancer, 2.19 (1.32-3.66); melanoma, 1.87 (1.55-2.26); testicular cancer, 1.76 (1.02-3.04); kidney cancer, 1.55 (1.08-2.23); and endometrial cancer, 1.31 (1.07-1.61). Associations were stronger for rarer cancers and at tissue sites with lower rates of stem cell division. There was generally little evidence of association between genetically increased telomere length and risk of psychiatric, autoimmune, inflammatory, diabetic, and other non-neoplastic diseases, except for coronary heart disease (OR, 0.78 [95% CI, 0.67-0.90]), abdominal aortic aneurysm (OR, 0.63 [95% CI, 0.49-0.81]), celiac disease (OR, 0.42 [95% CI, 0.28-0.61]) and interstitial lung disease (OR, 0.09 [95% CI, 0.05-0.15]).</AbstractText>
<AbstractText Label="Conclusions and Relevance" NlmCategory="UNASSIGNED">It is likely that longer telomeres increase risk for several cancers but reduce risk for some non-neoplastic diseases, including cardiovascular diseases.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><CollectiveName>Telomeres Mendelian Randomization Collaboration</CollectiveName>
</Author>
<Author ValidYN="Y"><LastName>Haycock</LastName>
<ForeName>Philip C</ForeName>
<Initials>PC</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Burgess</LastName>
<ForeName>Stephen</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nounu</LastName>
<ForeName>Aayah</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zheng</LastName>
<ForeName>Jie</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Okoli</LastName>
<ForeName>George N</ForeName>
<Initials>GN</Initials>
<AffiliationInfo><Affiliation>School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bowden</LastName>
<ForeName>Jack</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Wade</LastName>
<ForeName>Kaitlin Hazel</ForeName>
<Initials>KH</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Timpson</LastName>
<ForeName>Nicholas J</ForeName>
<Initials>NJ</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Evans</LastName>
<ForeName>David M</ForeName>
<Initials>DM</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England4University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Willeit</LastName>
<ForeName>Peter</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge, England5Department of Neurology, Innsbruck Medical University, Austria.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Aviv</LastName>
<ForeName>Abraham</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Center of Human Development and Aging, Department of Pediatrics, New Jersey Medical School, Rutgers, The State University of New Jersey.</Affiliation>
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</Author>
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<ForeName>Tom R</ForeName>
<Initials>TR</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Hemani</LastName>
<ForeName>Gibran</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
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</Author>
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<ForeName>Massimo</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London England8NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Ellis</LastName>
<ForeName>Hayley Patricia</ForeName>
<Initials>HP</Initials>
<AffiliationInfo><Affiliation>Brain Tumour Research Group, Institute of Clinical Neuroscience, Learning and Research Building, Southmead Hospital, University of Bristol.</Affiliation>
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</Author>
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<ForeName>Kathreena M</ForeName>
<Initials>KM</Initials>
<AffiliationInfo><Affiliation>Brain Tumour Research Group, Institute of Clinical Neuroscience, Learning and Research Building, Southmead Hospital, University of Bristol.</Affiliation>
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<Author ValidYN="Y"><LastName>Pooley</LastName>
<ForeName>Karen A</ForeName>
<Initials>KA</Initials>
<AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Eeles</LastName>
<ForeName>Rosalind A</ForeName>
<Initials>RA</Initials>
<AffiliationInfo><Affiliation>The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Lee</LastName>
<ForeName>Jeffrey E</ForeName>
<Initials>JE</Initials>
<AffiliationInfo><Affiliation>Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston.</Affiliation>
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<ForeName>Shenying</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston.</Affiliation>
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<ForeName>Wei V</ForeName>
<Initials>WV</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Applications & Support, The University of Texas MD Anderson Cancer Center, Houston.</Affiliation>
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<ForeName>Matthew H</ForeName>
<Initials>MH</Initials>
<AffiliationInfo><Affiliation>Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.</Affiliation>
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<ForeName>Lisa M</ForeName>
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<AffiliationInfo><Affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</Affiliation>
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<ForeName>Mark M</ForeName>
<Initials>MM</Initials>
<AffiliationInfo><Affiliation>Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, England.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.</Affiliation>
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<AffiliationInfo><Affiliation>Departments of Neurology and Public Health Sciences, University of Virginia Charlottesville, Virginia.</Affiliation>
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<Initials>HS</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Neurosciences, University of Cambridge, England.</Affiliation>
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<Initials>RJ</Initials>
<AffiliationInfo><Affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada21Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.</Affiliation>
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<AffiliationInfo><Affiliation>Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.</Affiliation>
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<Initials>AB</Initials>
<AffiliationInfo><Affiliation>Genetics and Computational Biology Division, QIMR Berghofer Medical Research Institute, Brisbane, Australia.</Affiliation>
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<Initials>TA</Initials>
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<AffiliationInfo><Affiliation>Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.</Affiliation>
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<Initials>R</Initials>
<AffiliationInfo><Affiliation>Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.</Affiliation>
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<Author ValidYN="Y"><LastName>Onland-Moret</LastName>
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<Initials>NC</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, the Netherlands.</Affiliation>
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<Initials>E</Initials>
<AffiliationInfo><Affiliation>Institute of Community Medicine, UiT The Arctic University of Norway, Tromso, Norway.</Affiliation>
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<AffiliationInfo><Affiliation>Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain.</Affiliation>
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<AffiliationInfo><Affiliation>Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark.</Affiliation>
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<AffiliationInfo><Affiliation>School of Public Health, Imperial College London, London, England.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Medical Biosciences, Umea University, Umea, Sweden.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Cardiovascular Sciences and the NIHR Leicester, Cardiovascular Biomedical Research Unit, University of Leicester, Glenfield Hospital, Leicester, England.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Cardiovascular Sciences and the NIHR Leicester, Cardiovascular Biomedical Research Unit, University of Leicester, Glenfield Hospital, Leicester, England.</Affiliation>
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<Initials>T</Initials>
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<Author ValidYN="Y"><LastName>Rotter</LastName>
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<Initials>JI</Initials>
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<Author ValidYN="Y"><LastName>Cotch</LastName>
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<Initials>MF</Initials>
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<Author ValidYN="Y"><LastName>Jensen</LastName>
<ForeName>Richard A</ForeName>
<Initials>RA</Initials>
<AffiliationInfo><Affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle104Department of Medicine, University of Washington, Seattle.</Affiliation>
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<Initials>M</Initials>
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<Author ValidYN="Y"><LastName>Dommisch</LastName>
<ForeName>Henrik</ForeName>
<Initials>H</Initials>
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<Author ValidYN="Y"><LastName>Schaefer</LastName>
<ForeName>Arne S</ForeName>
<Initials>AS</Initials>
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<Author ValidYN="Y"><LastName>Han</LastName>
<ForeName>Fang</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Pulmonary Medicine, Peking University People's Hospital, Beijing, China.</Affiliation>
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<Author ValidYN="Y"><LastName>Ollila</LastName>
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<Initials>HM</Initials>
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<Initials>RP</Initials>
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<Author ValidYN="Y"><LastName>Albagha</LastName>
<ForeName>Omar</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Doha, Qatar110Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.</Affiliation>
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<Author ValidYN="Y"><LastName>Ralston</LastName>
<ForeName>Stuart H</ForeName>
<Initials>SH</Initials>
<AffiliationInfo><Affiliation>Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.</Affiliation>
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<Author ValidYN="Y"><LastName>Zeng</LastName>
<ForeName>Chenjie</ForeName>
<Initials>C</Initials>
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<Author ValidYN="Y"><LastName>Zheng</LastName>
<ForeName>Wei</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.</Affiliation>
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<Author ValidYN="Y"><LastName>Shu</LastName>
<ForeName>Xiao-Ou</ForeName>
<Initials>XO</Initials>
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<Author ValidYN="Y"><LastName>Reis</LastName>
<ForeName>Andre</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.</Affiliation>
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<ForeName>Steffen</ForeName>
<Initials>S</Initials>
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<ForeName>Ulrike</ForeName>
<Initials>U</Initials>
<AffiliationInfo><Affiliation>Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Kawamura</LastName>
<ForeName>Yoshiya</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Psychiatry, Shonan Kamakura General Hospital, Kanagawa, Japan.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Otowa</LastName>
<ForeName>Takeshi</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan115Graduate School of Clinical Psychology, Teikyo Heisei University Major of Professional Clinical Psychology, Tokyo, Japan.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Sasaki</LastName>
<ForeName>Tsukasa</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Physical and Health Education, Graduate School of Education, University of Tokyo, Tokyo, Japan.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Hibberd</LastName>
<ForeName>Martin Lloyd</ForeName>
<Initials>ML</Initials>
<AffiliationInfo><Affiliation>Infectious Diseases, Genome Institute of Singapore, Singapore.</Affiliation>
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<Author ValidYN="Y"><LastName>Davila</LastName>
<ForeName>Sonia</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Human Genetics, Genome Institute of Singapore, Singapore.</Affiliation>
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<Initials>G</Initials>
<AffiliationInfo><Affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada119Departments of Medicine, Immunology, Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</Affiliation>
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<Author ValidYN="Y"><LastName>Siminovitch</LastName>
<ForeName>Katherine</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada119Departments of Medicine, Immunology, Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.</Affiliation>
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<Author ValidYN="Y"><LastName>Bei</LastName>
<ForeName>Jin-Xin</ForeName>
<Initials>JX</Initials>
<AffiliationInfo><Affiliation>Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.</Affiliation>
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<Author ValidYN="Y"><LastName>Zeng</LastName>
<ForeName>Yi-Xin</ForeName>
<Initials>YX</Initials>
<AffiliationInfo><Affiliation>Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China121Peking Union Medical College, Beijing, China.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Försti</LastName>
<ForeName>Asta</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany123Center for Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.</Affiliation>
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<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Bowang</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Landi</LastName>
<ForeName>Stefano</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Biology, University of Pisa, Pisa, Italy.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Franke</LastName>
<ForeName>Andre</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>University Hospital Schleswig-Holstein, Kiel, Germany.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Fischer</LastName>
<ForeName>Annegret</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>University Hospital Schleswig-Holstein, Kiel, Germany126Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.</Affiliation>
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<Author ValidYN="Y"><LastName>Ellinghaus</LastName>
<ForeName>David</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.</Affiliation>
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<Author ValidYN="Y"><LastName>Flores</LastName>
<ForeName>Carlos</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Tenerife, Spain128CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.</Affiliation>
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<Author ValidYN="Y"><LastName>Noth</LastName>
<ForeName>Imre</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.</Affiliation>
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<Author ValidYN="Y"><LastName>Ma</LastName>
<ForeName>Shwu-Fan</ForeName>
<Initials>SF</Initials>
<AffiliationInfo><Affiliation>Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.</Affiliation>
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<Author ValidYN="Y"><LastName>Foo</LastName>
<ForeName>Jia Nee</ForeName>
<Initials>JN</Initials>
<AffiliationInfo><Affiliation>Human Genetics, Genome Institute of Singapore, A*STAR, Singapore.</Affiliation>
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<ForeName>Jianjun</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Human Genetics, Genome Institute of Singapore, A*STAR, Singapore.</Affiliation>
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<Author ValidYN="Y"><LastName>Kim</LastName>
<ForeName>Jong-Won</ForeName>
<Initials>JW</Initials>
<AffiliationInfo><Affiliation>Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan, University School of Medicine, Gangnam-gu, Seoul, South Korea.</Affiliation>
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<Author ValidYN="Y"><LastName>Cox</LastName>
<ForeName>David G</ForeName>
<Initials>DG</Initials>
<AffiliationInfo><Affiliation>Cancer Research Center of Lyon, INSERM U1052, Lyon, France.</Affiliation>
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<Author ValidYN="Y"><LastName>Delattre</LastName>
<ForeName>Olivier</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Inserm U830, Institut Curie, PSL University, Paris, France.</Affiliation>
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<Author ValidYN="Y"><LastName>Mirabeau</LastName>
<ForeName>Olivier</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Inserm U830, Institut Curie, PSL University, Paris, France.</Affiliation>
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<Author ValidYN="Y"><LastName>Skibola</LastName>
<ForeName>Christine F</ForeName>
<Initials>CF</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, University of Alabama at Birmingham.</Affiliation>
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<Author ValidYN="Y"><LastName>Tang</LastName>
<ForeName>Clara S</ForeName>
<Initials>CS</Initials>
<AffiliationInfo><Affiliation>Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.</Affiliation>
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<Author ValidYN="Y"><LastName>Garcia-Barcelo</LastName>
<ForeName>Merce</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Chang</LastName>
<ForeName>Kai-Ping</ForeName>
<Initials>KP</Initials>
<AffiliationInfo><Affiliation>Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital at Lin-Kou, Taoyuan, Taiwan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Su</LastName>
<ForeName>Wen-Hui</ForeName>
<Initials>WH</Initials>
<AffiliationInfo><Affiliation>Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital at Lin-Kou, Taoyuan, Taiwan137Department of Biomedical Sciences, Graduate Institute of Biomedical Sciences, College of Medicine, Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.</Affiliation>
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<Author ValidYN="Y"><LastName>Chang</LastName>
<ForeName>Yu-Sun</ForeName>
<Initials>YS</Initials>
<AffiliationInfo><Affiliation>Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.</Affiliation>
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<Author ValidYN="Y"><LastName>Martin</LastName>
<ForeName>Nicholas G</ForeName>
<Initials>NG</Initials>
<AffiliationInfo><Affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</Affiliation>
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<Author ValidYN="Y"><LastName>Gordon</LastName>
<ForeName>Scott</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>QIMR Berghofer Medical Research Institute, Brisbane, Australia.</Affiliation>
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<Author ValidYN="Y"><LastName>Wade</LastName>
<ForeName>Tracey D</ForeName>
<Initials>TD</Initials>
<AffiliationInfo><Affiliation>School of Psychology, Flinders University, Adelaide, South Australia.</Affiliation>
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<Author ValidYN="Y"><LastName>Lee</LastName>
<ForeName>Chaeyoung</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>School of Systems Biomedical Science, Soongsil University, Dongjak-gu, Seoul, South Korea.</Affiliation>
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<Author ValidYN="Y"><LastName>Kubo</LastName>
<ForeName>Michiaki</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>RIKEN Center for Integrative Medical Science, Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, Japan.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Cha</LastName>
<ForeName>Pei-Chieng</ForeName>
<Initials>PC</Initials>
<AffiliationInfo><Affiliation>Division of Molecular Brain Science, Kobe University Graduate School of Medicine, Kusunoki-chou, Chuo-ku, Kobe, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nakamura</LastName>
<ForeName>Yusuke</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Center for Personalized Therapeutics, The University of Chicago, Chicago, Illinois.</Affiliation>
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<Author ValidYN="Y"><LastName>Levy</LastName>
<ForeName>Daniel</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>The NHLBI's Framingham Heart Study, Framingham, Massachusetts, Population Sciences Branch of the National Heart, Lung, and Blood Institute, Bethesda, Maryland.</Affiliation>
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<Author ValidYN="Y"><LastName>Kimura</LastName>
<ForeName>Masayuki</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Center of Human Development and Aging, Department of Pediatrics, New Jersey Medical School, Rutgers, The State University of New Jersey.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Hwang</LastName>
<ForeName>Shih-Jen</ForeName>
<Initials>SJ</Initials>
<AffiliationInfo><Affiliation>The NHLBI's Framingham Heart Study, Framingham, Massachusetts, Population Sciences Branch of the National Heart, Lung, and Blood Institute, Bethesda, Maryland.</Affiliation>
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<Author ValidYN="Y"><LastName>Hunt</LastName>
<ForeName>Steven</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Genetic Medicine, Weill Cornell Medicine in Qatar, Doha, Qatar.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Spector</LastName>
<ForeName>Tim</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Soranzo</LastName>
<ForeName>Nicole</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton Cambridge, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Manichaikul</LastName>
<ForeName>Ani W</ForeName>
<Initials>AW</Initials>
<AffiliationInfo><Affiliation>Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville.</Affiliation>
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<Author ValidYN="Y"><LastName>Barr</LastName>
<ForeName>R Graham</ForeName>
<Initials>RG</Initials>
<AffiliationInfo><Affiliation>Department of Medicine and Department of Epidemiology, Columbia University Medical Center, New York, New York.</Affiliation>
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<Author ValidYN="Y"><LastName>Kahali</LastName>
<ForeName>Bratati</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, Division of Gastroenterology and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor.</Affiliation>
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<Author ValidYN="Y"><LastName>Speliotes</LastName>
<ForeName>Elizabeth</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, Division of Gastroenterology and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Yerges-Armstrong</LastName>
<ForeName>Laura M</ForeName>
<Initials>LM</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, University of Maryland, Baltimore.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Cheng</LastName>
<ForeName>Ching-Yu</ForeName>
<Initials>CY</Initials>
<AffiliationInfo><Affiliation>Singapore Eye Research Institute, Singapore National Eye Center, Singapore152Department of Ophthalmology, National University of Singapore and National University Health System, Singapore153Duke-NUS Medical School, Singapore.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Jonas</LastName>
<ForeName>Jost B</ForeName>
<Initials>JB</Initials>
<AffiliationInfo><Affiliation>Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China155Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Wong</LastName>
<ForeName>Tien Yin</ForeName>
<Initials>TY</Initials>
<AffiliationInfo><Affiliation>Singapore Eye Research Institute, Singapore National Eye Center, Singapore152Department of Ophthalmology, National University of Singapore and National University Health System, Singapore153Duke-NUS Medical School, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fogh</LastName>
<ForeName>Isabella</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Lin</LastName>
<ForeName>Kuang</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Powell</LastName>
<ForeName>John F</ForeName>
<Initials>JF</Initials>
<AffiliationInfo><Affiliation>Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Rice</LastName>
<ForeName>Kenneth</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Biostatistics, University of Washington, Seattle.</Affiliation>
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<Author ValidYN="Y"><LastName>Relton</LastName>
<ForeName>Caroline L</ForeName>
<Initials>CL</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Martin</LastName>
<ForeName>Richard M</ForeName>
<Initials>RM</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England158University of Bristol/University Hospitals Bristol NHS Foundation Trust National Institute for Health Research Bristol Nutrition Biomedical Research Unit, Bristol, England.</Affiliation>
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<Author ValidYN="Y"><LastName>Davey Smith</LastName>
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<Initials>G</Initials>
<AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.</Affiliation>
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   |texte=   Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
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This area was generated with Dilib version V0.6.33.
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	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les relations entre la France et l'Australie

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

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