Genome-wide association study identifies multiple risk loci for renal cell carcinoma.
Identifieur interne : 000B11 ( PubMed/Corpus ); précédent : 000B10; suivant : 000B12Genome-wide association study identifies multiple risk loci for renal cell carcinoma.
Auteurs : Ghislaine Scelo ; Mark P. Purdue ; Kevin M. Brown ; Mattias Johansson ; Zhaoming Wang ; Jeanette E. Eckel-Passow ; Yuanqing Ye ; Jonathan N. Hofmann ; Jiyeon Choi ; Matthieu Foll ; Valerie Gaborieau ; Mitchell J. Machiela ; Leandro M. Colli ; Peng Li ; Joshua N. Sampson ; Behnoush Abedi-Ardekani ; Celine Besse ; Helene Blanche ; Anne Boland ; Laurie Burdette ; Amelie Chabrier ; Geoffroy Durand ; Florence Le Calvez-Kelm ; Egor Prokhortchouk ; Nivonirina Robinot ; Konstantin G. Skryabin ; Magdalena B. Wozniak ; Meredith Yeager ; Gordana Basta-Jovanovic ; Zoran Dzamic ; Lenka Foretova ; Ivana Holcatova ; Vladimir Janout ; Dana Mates ; Anush Mukeriya ; Stefan Rascu ; David Zaridze ; Vladimir Bencko ; Cezary Cybulski ; Eleonora Fabianova ; Viorel Jinga ; Jolanta Lissowska ; Jan Lubinski ; Marie Navratilova ; Peter Rudnai ; Neonila Szeszenia-Dabrowska ; Simone Benhamou ; Geraldine Cancel-Tassin ; Olivier Cussenot ; Laura Baglietto ; Heiner Boeing ; Kay-Tee Khaw ; Elisabete Weiderpass ; Borje Ljungberg ; Raviprakash T. Sitaram ; Fiona Bruinsma ; Susan J. Jordan ; Gianluca Severi ; Ingrid Winship ; Kristian Hveem ; Lars J. Vatten ; Tony Fletcher ; Kvetoslava Koppova ; Susanna C. Larsson ; Alicja Wolk ; Rosamonde E. Banks ; Peter J. Selby ; Douglas F. Easton ; Paul Pharoah ; Gabriella Andreotti ; Laura E Beane Freeman ; Stella Koutros ; Demetrius Albanes ; Satu M Nnistö ; Stephanie Weinstein ; Peter E. Clark ; Todd L. Edwards ; Loren Lipworth ; Susan M. Gapstur ; Victoria L. Stevens ; Hallie Carol ; Matthew L. Freedman ; Mark M. Pomerantz ; Eunyoung Cho ; Peter Kraft ; Mark A. Preston ; Kathryn M. Wilson ; J. Michael Gaziano ; Howard D. Sesso ; Amanda Black ; Neal D. Freedman ; Wen-Yi Huang ; John G. Anema ; Richard J. Kahnoski ; Brian R. Lane ; Sabrina L. Noyes ; David Petillo ; Bin Tean Teh ; Ulrike Peters ; Emily White ; Garnet L. Anderson ; Lisa Johnson ; Juhua Luo ; Julie Buring ; I-Min Lee ; Wong-Ho Chow ; Lee E. Moore ; Christopher Wood ; Timothy Eisen ; Marc Henrion ; James Larkin ; Poulami Barman ; Bradley C. Leibovich ; Toni K. Choueiri ; G. Mark Lathrop ; Nathaniel Rothman ; Jean-Francois Deleuze ; James D. Mckay ; Alexander S. Parker ; Xifeng Wu ; Richard S. Houlston ; Paul Brennan ; Stephen J. ChanockSource :
- Nature communications [ 2041-1723 ] ; 2017.
Abstract
Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10(-10)), 3p22.1 (rs67311347, P=2.5 × 10(-8)), 3q26.2 (rs10936602, P=8.8 × 10(-9)), 8p21.3 (rs2241261, P=5.8 × 10(-9)), 10q24.33-q25.1 (rs11813268, P=3.9 × 10(-8)), 11q22.3 (rs74911261, P=2.1 × 10(-10)) and 14q24.2 (rs4903064, P=2.2 × 10(-24)). Expression quantitative trait analyses suggest plausible candidate genes at these regions that may contribute to RCC susceptibility.
DOI: 10.1038/ncomms15724
PubMed: 28598434
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pubmed:28598434Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genome-wide association study identifies multiple risk loci for renal cell carcinoma.</title><author><name sortKey="Scelo, Ghislaine" sort="Scelo, Ghislaine" uniqKey="Scelo G" first="Ghislaine" last="Scelo">Ghislaine Scelo</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P" last="Purdue">Mark P. Purdue</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Brown, Kevin M" sort="Brown, Kevin M" uniqKey="Brown K" first="Kevin M" last="Brown">Kevin M. Brown</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Johansson, Mattias" sort="Johansson, Mattias" uniqKey="Johansson M" first="Mattias" last="Johansson">Mattias Johansson</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation><nlm:affiliation>Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Eckel Passow, Jeanette E" sort="Eckel Passow, Jeanette E" uniqKey="Eckel Passow J" first="Jeanette E" last="Eckel-Passow">Jeanette E. Eckel-Passow</name><affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ye, Yuanqing" sort="Ye, Yuanqing" uniqKey="Ye Y" first="Yuanqing" last="Ye">Yuanqing Ye</name><affiliation><nlm:affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hofmann, Jonathan N" sort="Hofmann, Jonathan N" uniqKey="Hofmann J" first="Jonathan N" last="Hofmann">Jonathan N. Hofmann</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Choi, Jiyeon" sort="Choi, Jiyeon" uniqKey="Choi J" first="Jiyeon" last="Choi">Jiyeon Choi</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Foll, Matthieu" sort="Foll, Matthieu" uniqKey="Foll M" first="Matthieu" last="Foll">Matthieu Foll</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Gaborieau, Valerie" sort="Gaborieau, Valerie" uniqKey="Gaborieau V" first="Valerie" last="Gaborieau">Valerie Gaborieau</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Machiela, Mitchell J" sort="Machiela, Mitchell J" uniqKey="Machiela M" first="Mitchell J" last="Machiela">Mitchell J. Machiela</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Colli, Leandro M" sort="Colli, Leandro M" uniqKey="Colli L" first="Leandro M" last="Colli">Leandro M. Colli</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Peng" sort="Li, Peng" uniqKey="Li P" first="Peng" last="Li">Peng Li</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Sampson, Joshua N" sort="Sampson, Joshua N" uniqKey="Sampson J" first="Joshua N" last="Sampson">Joshua N. Sampson</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Abedi Ardekani, Behnoush" sort="Abedi Ardekani, Behnoush" uniqKey="Abedi Ardekani B" first="Behnoush" last="Abedi-Ardekani">Behnoush Abedi-Ardekani</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Besse, Celine" sort="Besse, Celine" uniqKey="Besse C" first="Celine" last="Besse">Celine Besse</name><affiliation><nlm:affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</nlm:affiliation></affiliation></author><author><name sortKey="Blanche, Helene" sort="Blanche, Helene" uniqKey="Blanche H" first="Helene" last="Blanche">Helene Blanche</name><affiliation><nlm:affiliation>Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain, 75010 Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Boland, Anne" sort="Boland, Anne" uniqKey="Boland A" first="Anne" last="Boland">Anne Boland</name><affiliation><nlm:affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</nlm:affiliation></affiliation></author><author><name sortKey="Burdette, Laurie" sort="Burdette, Laurie" uniqKey="Burdette L" first="Laurie" last="Burdette">Laurie Burdette</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chabrier, Amelie" sort="Chabrier, Amelie" uniqKey="Chabrier A" first="Amelie" last="Chabrier">Amelie Chabrier</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Durand, Geoffroy" sort="Durand, Geoffroy" uniqKey="Durand G" first="Geoffroy" last="Durand">Geoffroy Durand</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Le Calvez Kelm, Florence" sort="Le Calvez Kelm, Florence" uniqKey="Le Calvez Kelm F" first="Florence" last="Le Calvez-Kelm">Florence Le Calvez-Kelm</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Prokhortchouk, Egor" sort="Prokhortchouk, Egor" uniqKey="Prokhortchouk E" first="Egor" last="Prokhortchouk">Egor Prokhortchouk</name><affiliation><nlm:affiliation>Center 'Bioengineering' of the Russian Academy of Sciences, Moscow 117312, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="Robinot, Nivonirina" sort="Robinot, Nivonirina" uniqKey="Robinot N" first="Nivonirina" last="Robinot">Nivonirina Robinot</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Skryabin, Konstantin G" sort="Skryabin, Konstantin G" uniqKey="Skryabin K" first="Konstantin G" last="Skryabin">Konstantin G. 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Sitaram</name><affiliation><nlm:affiliation>Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, 901 85 Umeå, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Bruinsma, Fiona" sort="Bruinsma, Fiona" uniqKey="Bruinsma F" first="Fiona" last="Bruinsma">Fiona Bruinsma</name><affiliation><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Jordan, Susan J" sort="Jordan, Susan J" uniqKey="Jordan S" first="Susan J" last="Jordan">Susan J. Jordan</name><affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:affiliation>Centre de Recherche en Épidémiologie et Santé des Populations (CESP, Inserm U1018), Université Paris-Saclay, UPS, UVSQ, Gustave Roussy, 94805 Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Winship, Ingrid" sort="Winship, Ingrid" uniqKey="Winship I" first="Ingrid" last="Winship">Ingrid Winship</name><affiliation><nlm:affiliation>Department of Medicine, The University of Melbourne, Melbourne, Victoria 3010, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><affiliation><nlm:affiliation>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway.</nlm:affiliation></affiliation></author><author><name sortKey="Vatten, Lars J" sort="Vatten, Lars J" uniqKey="Vatten L" first="Lars J" last="Vatten">Lars J. Vatten</name><affiliation><nlm:affiliation>Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim 7491, Norway.</nlm:affiliation></affiliation></author><author><name sortKey="Fletcher, Tony" sort="Fletcher, Tony" uniqKey="Fletcher T" first="Tony" last="Fletcher">Tony Fletcher</name><affiliation><nlm:affiliation>London School of Hygiene and Tropical Medicine, University of London, London WC1H 9SH, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Koppova, Kvetoslava" sort="Koppova, Kvetoslava" uniqKey="Koppova K" first="Kvetoslava" last="Koppova">Kvetoslava Koppova</name><affiliation><nlm:affiliation>Regional Authority of Public Health in Banska Bystrica, 975 56 Banska Bystrica, Slovakia.</nlm:affiliation></affiliation></author><author><name sortKey="Larsson, Susanna C" sort="Larsson, Susanna C" uniqKey="Larsson S" first="Susanna C" last="Larsson">Susanna C. Larsson</name><affiliation><nlm:affiliation>Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name><affiliation><nlm:affiliation>Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Banks, Rosamonde E" sort="Banks, Rosamonde E" uniqKey="Banks R" first="Rosamonde E" last="Banks">Rosamonde E. Banks</name><affiliation><nlm:affiliation>Leeds Institute of Cancer and Pathology, University of Leeds, Cancer Research Building, St James's University Hospital, Leeds LS9 7TF, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Selby, Peter J" sort="Selby, Peter J" uniqKey="Selby P" first="Peter J" last="Selby">Peter J. Selby</name><affiliation><nlm:affiliation>Leeds Institute of Cancer and Pathology, University of Leeds, Cancer Research Building, St James's University Hospital, Leeds LS9 7TF, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation><nlm:affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Pharoah, Paul" sort="Pharoah, Paul" uniqKey="Pharoah P" first="Paul" last="Pharoah">Paul Pharoah</name><affiliation><nlm:affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Andreotti, Gabriella" sort="Andreotti, Gabriella" uniqKey="Andreotti G" first="Gabriella" last="Andreotti">Gabriella Andreotti</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Freeman, Laura E Beane" sort="Freeman, Laura E Beane" uniqKey="Freeman L" first="Laura E Beane" last="Freeman">Laura E Beane Freeman</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Koutros, Stella" sort="Koutros, Stella" uniqKey="Koutros S" first="Stella" last="Koutros">Stella Koutros</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation><nlm:affiliation>Department of Health, National Institute for Health and Welfare, 00271 Helsinki, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Weinstein, Stephanie" sort="Weinstein, Stephanie" uniqKey="Weinstein S" first="Stephanie" last="Weinstein">Stephanie Weinstein</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Clark, Peter E" sort="Clark, Peter E" uniqKey="Clark P" first="Peter E" last="Clark">Peter E. Clark</name><affiliation><nlm:affiliation>Vanderbilt-Ingram Cancer Center, Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Edwards, Todd L" sort="Edwards, Todd L" uniqKey="Edwards T" first="Todd L" last="Edwards">Todd L. Edwards</name><affiliation><nlm:affiliation>Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37209, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lipworth, Loren" sort="Lipworth, Loren" uniqKey="Lipworth L" first="Loren" last="Lipworth">Loren Lipworth</name><affiliation><nlm:affiliation>Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gapstur, Susan M" sort="Gapstur, Susan M" uniqKey="Gapstur S" first="Susan M" last="Gapstur">Susan M. Gapstur</name><affiliation><nlm:affiliation>American Cancer Society, Atlanta, Georgia 30303, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Stevens, Victoria L" sort="Stevens, Victoria L" uniqKey="Stevens V" first="Victoria L" last="Stevens">Victoria L. Stevens</name><affiliation><nlm:affiliation>American Cancer Society, Atlanta, Georgia 30303, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Carol, Hallie" sort="Carol, Hallie" uniqKey="Carol H" first="Hallie" last="Carol">Hallie Carol</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Freedman, Matthew L" sort="Freedman, Matthew L" uniqKey="Freedman M" first="Matthew L" last="Freedman">Matthew L. Freedman</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Pomerantz, Mark M" sort="Pomerantz, Mark M" uniqKey="Pomerantz M" first="Mark M" last="Pomerantz">Mark M. Pomerantz</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Cho, Eunyoung" sort="Cho, Eunyoung" uniqKey="Cho E" first="Eunyoung" last="Cho">Eunyoung Cho</name><affiliation><nlm:affiliation>Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Preston, Mark A" sort="Preston, Mark A" uniqKey="Preston M" first="Mark A" last="Preston">Mark A. Preston</name><affiliation><nlm:affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wilson, Kathryn M" sort="Wilson, Kathryn M" uniqKey="Wilson K" first="Kathryn M" last="Wilson">Kathryn M. Wilson</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Michael Gaziano, J" sort="Michael Gaziano, J" uniqKey="Michael Gaziano J" first="J" last="Michael Gaziano">J. Michael Gaziano</name><affiliation><nlm:affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D" last="Sesso">Howard D. Sesso</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Black, Amanda" sort="Black, Amanda" uniqKey="Black A" first="Amanda" last="Black">Amanda Black</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Freedman, Neal D" sort="Freedman, Neal D" uniqKey="Freedman N" first="Neal D" last="Freedman">Neal D. Freedman</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Huang, Wen Yi" sort="Huang, Wen Yi" uniqKey="Huang W" first="Wen-Yi" last="Huang">Wen-Yi Huang</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Anema, John G" sort="Anema, John G" uniqKey="Anema J" first="John G" last="Anema">John G. Anema</name><affiliation><nlm:affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kahnoski, Richard J" sort="Kahnoski, Richard J" uniqKey="Kahnoski R" first="Richard J" last="Kahnoski">Richard J. Kahnoski</name><affiliation><nlm:affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lane, Brian R" sort="Lane, Brian R" uniqKey="Lane B" first="Brian R" last="Lane">Brian R. Lane</name><affiliation><nlm:affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Noyes, Sabrina L" sort="Noyes, Sabrina L" uniqKey="Noyes S" first="Sabrina L" last="Noyes">Sabrina L. Noyes</name><affiliation><nlm:affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Petillo, David" sort="Petillo, David" uniqKey="Petillo D" first="David" last="Petillo">David Petillo</name><affiliation><nlm:affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Teh, Bin Tean" sort="Teh, Bin Tean" uniqKey="Teh B" first="Bin Tean" last="Teh">Bin Tean Teh</name><affiliation><nlm:affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation><nlm:affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:affiliation></affiliation></author><author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><affiliation><nlm:affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Anderson, Garnet L" sort="Anderson, Garnet L" uniqKey="Anderson G" first="Garnet L" last="Anderson">Garnet L. Anderson</name><affiliation><nlm:affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Johnson, Lisa" sort="Johnson, Lisa" uniqKey="Johnson L" first="Lisa" last="Johnson">Lisa Johnson</name><affiliation><nlm:affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Luo, Juhua" sort="Luo, Juhua" uniqKey="Luo J" first="Juhua" last="Luo">Juhua Luo</name><affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health Indiana University Bloomington, Bloomington, Indiana 47405, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Buring, Julie" sort="Buring, Julie" uniqKey="Buring J" first="Julie" last="Buring">Julie Buring</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lee, I Min" sort="Lee, I Min" uniqKey="Lee I" first="I-Min" last="Lee">I-Min Lee</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chow, Wong Ho" sort="Chow, Wong Ho" uniqKey="Chow W" first="Wong-Ho" last="Chow">Wong-Ho Chow</name><affiliation><nlm:affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Moore, Lee E" sort="Moore, Lee E" uniqKey="Moore L" first="Lee E" last="Moore">Lee E. Moore</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wood, Christopher" sort="Wood, Christopher" uniqKey="Wood C" first="Christopher" last="Wood">Christopher Wood</name><affiliation><nlm:affiliation>Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Eisen, Timothy" sort="Eisen, Timothy" uniqKey="Eisen T" first="Timothy" last="Eisen">Timothy Eisen</name><affiliation><nlm:affiliation>Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Henrion, Marc" sort="Henrion, Marc" uniqKey="Henrion M" first="Marc" last="Henrion">Marc Henrion</name><affiliation><nlm:affiliation>Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Larkin, James" sort="Larkin, James" uniqKey="Larkin J" first="James" last="Larkin">James Larkin</name><affiliation><nlm:affiliation>Medical Oncology, Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Barman, Poulami" sort="Barman, Poulami" uniqKey="Barman P" first="Poulami" last="Barman">Poulami Barman</name><affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Leibovich, Bradley C" sort="Leibovich, Bradley C" uniqKey="Leibovich B" first="Bradley C" last="Leibovich">Bradley C. Leibovich</name><affiliation><nlm:affiliation>Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55902, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Choueiri, Toni K" sort="Choueiri, Toni K" uniqKey="Choueiri T" first="Toni K" last="Choueiri">Toni K. Choueiri</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mark Lathrop, G" sort="Mark Lathrop, G" uniqKey="Mark Lathrop G" first="G" last="Mark Lathrop">G. Mark Lathrop</name><affiliation><nlm:affiliation>McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada H3A 0G1.</nlm:affiliation></affiliation></author><author><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Deleuze, Jean Francois" sort="Deleuze, Jean Francois" uniqKey="Deleuze J" first="Jean-Francois" last="Deleuze">Jean-Francois Deleuze</name><affiliation><nlm:affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</nlm:affiliation></affiliation></author><author><name sortKey="Mckay, James D" sort="Mckay, James D" uniqKey="Mckay J" first="James D" last="Mckay">James D. Mckay</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Parker, Alexander S" sort="Parker, Alexander S" uniqKey="Parker A" first="Alexander S" last="Parker">Alexander S. Parker</name><affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Jacksonville, Florida 32224, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wu, Xifeng" sort="Wu, Xifeng" uniqKey="Wu X" first="Xifeng" last="Wu">Xifeng Wu</name><affiliation><nlm:affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Houlston, Richard S" sort="Houlston, Richard S" uniqKey="Houlston R" first="Richard S" last="Houlston">Richard S. Houlston</name><affiliation><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28598434</idno><idno type="pmid">28598434</idno><idno type="doi">10.1038/ncomms15724</idno><idno type="wicri:Area/PubMed/Corpus">000B11</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000B11</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Genome-wide association study identifies multiple risk loci for renal cell carcinoma.</title><author><name sortKey="Scelo, Ghislaine" sort="Scelo, Ghislaine" uniqKey="Scelo G" first="Ghislaine" last="Scelo">Ghislaine Scelo</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P" last="Purdue">Mark P. Purdue</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Brown, Kevin M" sort="Brown, Kevin M" uniqKey="Brown K" first="Kevin M" last="Brown">Kevin M. Brown</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Johansson, Mattias" sort="Johansson, Mattias" uniqKey="Johansson M" first="Mattias" last="Johansson">Mattias Johansson</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation><nlm:affiliation>Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Eckel Passow, Jeanette E" sort="Eckel Passow, Jeanette E" uniqKey="Eckel Passow J" first="Jeanette E" last="Eckel-Passow">Jeanette E. Eckel-Passow</name><affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ye, Yuanqing" sort="Ye, Yuanqing" uniqKey="Ye Y" first="Yuanqing" last="Ye">Yuanqing Ye</name><affiliation><nlm:affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hofmann, Jonathan N" sort="Hofmann, Jonathan N" uniqKey="Hofmann J" first="Jonathan N" last="Hofmann">Jonathan N. Hofmann</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Choi, Jiyeon" sort="Choi, Jiyeon" uniqKey="Choi J" first="Jiyeon" last="Choi">Jiyeon Choi</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Foll, Matthieu" sort="Foll, Matthieu" uniqKey="Foll M" first="Matthieu" last="Foll">Matthieu Foll</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Gaborieau, Valerie" sort="Gaborieau, Valerie" uniqKey="Gaborieau V" first="Valerie" last="Gaborieau">Valerie Gaborieau</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Machiela, Mitchell J" sort="Machiela, Mitchell J" uniqKey="Machiela M" first="Mitchell J" last="Machiela">Mitchell J. Machiela</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Colli, Leandro M" sort="Colli, Leandro M" uniqKey="Colli L" first="Leandro M" last="Colli">Leandro M. Colli</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Peng" sort="Li, Peng" uniqKey="Li P" first="Peng" last="Li">Peng Li</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Sampson, Joshua N" sort="Sampson, Joshua N" uniqKey="Sampson J" first="Joshua N" last="Sampson">Joshua N. Sampson</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Abedi Ardekani, Behnoush" sort="Abedi Ardekani, Behnoush" uniqKey="Abedi Ardekani B" first="Behnoush" last="Abedi-Ardekani">Behnoush Abedi-Ardekani</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Besse, Celine" sort="Besse, Celine" uniqKey="Besse C" first="Celine" last="Besse">Celine Besse</name><affiliation><nlm:affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</nlm:affiliation></affiliation></author><author><name sortKey="Blanche, Helene" sort="Blanche, Helene" uniqKey="Blanche H" first="Helene" last="Blanche">Helene Blanche</name><affiliation><nlm:affiliation>Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain, 75010 Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Boland, Anne" sort="Boland, Anne" uniqKey="Boland A" first="Anne" last="Boland">Anne Boland</name><affiliation><nlm:affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</nlm:affiliation></affiliation></author><author><name sortKey="Burdette, Laurie" sort="Burdette, Laurie" uniqKey="Burdette L" first="Laurie" last="Burdette">Laurie Burdette</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chabrier, Amelie" sort="Chabrier, Amelie" uniqKey="Chabrier A" first="Amelie" last="Chabrier">Amelie Chabrier</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Durand, Geoffroy" sort="Durand, Geoffroy" uniqKey="Durand G" first="Geoffroy" last="Durand">Geoffroy Durand</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Le Calvez Kelm, Florence" sort="Le Calvez Kelm, Florence" uniqKey="Le Calvez Kelm F" first="Florence" last="Le Calvez-Kelm">Florence Le Calvez-Kelm</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Prokhortchouk, Egor" sort="Prokhortchouk, Egor" uniqKey="Prokhortchouk E" first="Egor" last="Prokhortchouk">Egor Prokhortchouk</name><affiliation><nlm:affiliation>Center 'Bioengineering' of the Russian Academy of Sciences, Moscow 117312, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="Robinot, Nivonirina" sort="Robinot, Nivonirina" uniqKey="Robinot N" first="Nivonirina" last="Robinot">Nivonirina Robinot</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Skryabin, Konstantin G" sort="Skryabin, Konstantin G" uniqKey="Skryabin K" first="Konstantin G" last="Skryabin">Konstantin G. Skryabin</name><affiliation><nlm:affiliation>Center 'Bioengineering' of the Russian Academy of Sciences, Moscow 117312, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="Wozniak, Magdalena B" sort="Wozniak, Magdalena B" uniqKey="Wozniak M" first="Magdalena B" last="Wozniak">Magdalena B. Wozniak</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Yeager, Meredith" sort="Yeager, Meredith" uniqKey="Yeager M" first="Meredith" last="Yeager">Meredith Yeager</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Basta Jovanovic, Gordana" sort="Basta Jovanovic, Gordana" uniqKey="Basta Jovanovic G" first="Gordana" last="Basta-Jovanovic">Gordana Basta-Jovanovic</name><affiliation><nlm:affiliation>Institute of Pathology, School of Medicine, University of Belgrade, 11000 Belgrade, Serbia.</nlm:affiliation></affiliation></author><author><name sortKey="Dzamic, Zoran" sort="Dzamic, Zoran" uniqKey="Dzamic Z" first="Zoran" last="Dzamic">Zoran Dzamic</name><affiliation><nlm:affiliation>Clinical Center of Serbia (KCS), Clinic of Urology, University of Belgrade-Faculty of Medicine, 11000 Belgrade, Serbia.</nlm:affiliation></affiliation></author><author><name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name><affiliation><nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Holcatova, Ivana" sort="Holcatova, Ivana" uniqKey="Holcatova I" first="Ivana" last="Holcatova">Ivana Holcatova</name><affiliation><nlm:affiliation>2nd Faculty of Medicine, Institute of Public Health and Preventive Medicine, Charles University, 150 06 Prague 5, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Janout, Vladimir" sort="Janout, Vladimir" uniqKey="Janout V" first="Vladimir" last="Janout">Vladimir Janout</name><affiliation><nlm:affiliation>Department of Preventive Medicine, Faculty of Medicine, Palacky University, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Mates, Dana" sort="Mates, Dana" uniqKey="Mates D" first="Dana" last="Mates">Dana Mates</name><affiliation><nlm:affiliation>National Institute of Public Health, 050463 Bucharest, Romania.</nlm:affiliation></affiliation></author><author><name sortKey="Mukeriya, Anush" sort="Mukeriya, Anush" uniqKey="Mukeriya A" first="Anush" last="Mukeriya">Anush Mukeriya</name><affiliation><nlm:affiliation>Russian N.N. Blokhin Cancer Research Centre, Moscow 115478, Russian Federation.</nlm:affiliation></affiliation></author><author><name sortKey="Rascu, Stefan" sort="Rascu, Stefan" uniqKey="Rascu S" first="Stefan" last="Rascu">Stefan Rascu</name><affiliation><nlm:affiliation>Carol Davila University of Medicine and Pharmacy, Th. Burghele Hospital, 050659 Bucharest, Romania.</nlm:affiliation></affiliation></author><author><name sortKey="Zaridze, David" sort="Zaridze, David" uniqKey="Zaridze D" first="David" last="Zaridze">David Zaridze</name><affiliation><nlm:affiliation>Russian N.N. Blokhin Cancer Research Centre, Moscow 115478, Russian Federation.</nlm:affiliation></affiliation></author><author><name sortKey="Bencko, Vladimir" sort="Bencko, Vladimir" uniqKey="Bencko V" first="Vladimir" last="Bencko">Vladimir Bencko</name><affiliation><nlm:affiliation>First Faculty of Medicine, Institute of Hygiene and Epidemiology, Charles University, 128 00 Prague 2, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name><affiliation><nlm:affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, 70-204 Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Fabianova, Eleonora" sort="Fabianova, Eleonora" uniqKey="Fabianova E" first="Eleonora" last="Fabianova">Eleonora Fabianova</name><affiliation><nlm:affiliation>Regional Authority of Public Health in Banska Bystrica, 975 56 Banska Bystrica, Slovakia.</nlm:affiliation></affiliation></author><author><name sortKey="Jinga, Viorel" sort="Jinga, Viorel" uniqKey="Jinga V" first="Viorel" last="Jinga">Viorel Jinga</name><affiliation><nlm:affiliation>Carol Davila University of Medicine and Pharmacy, Th. Burghele Hospital, 050659 Bucharest, Romania.</nlm:affiliation></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation><nlm:affiliation>The M Sklodowska-Curie Cancer Center and Institute of Oncology, 02-034 Warsaw, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation><nlm:affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, 70-204 Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Navratilova, Marie" sort="Navratilova, Marie" uniqKey="Navratilova M" first="Marie" last="Navratilova">Marie Navratilova</name><affiliation><nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Rudnai, Peter" sort="Rudnai, Peter" uniqKey="Rudnai P" first="Peter" last="Rudnai">Peter Rudnai</name><affiliation><nlm:affiliation>National Public Health Center, National Directorate of Environmental Health, 1097 Budapest, Hungary.</nlm:affiliation></affiliation></author><author><name sortKey="Szeszenia Dabrowska, Neonila" sort="Szeszenia Dabrowska, Neonila" uniqKey="Szeszenia Dabrowska N" first="Neonila" last="Szeszenia-Dabrowska">Neonila Szeszenia-Dabrowska</name><affiliation><nlm:affiliation>Department of Epidemiology, Institute of Occupational Medicine, 91-348 Lodz, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Benhamou, Simone" sort="Benhamou, Simone" uniqKey="Benhamou S" first="Simone" last="Benhamou">Simone Benhamou</name><affiliation><nlm:affiliation>Université Paris Diderot, INSERM, Unité Variabilité Génétique et Maladies Humaines, 75010 Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Cancel Tassin, Geraldine" sort="Cancel Tassin, Geraldine" uniqKey="Cancel Tassin G" first="Geraldine" last="Cancel-Tassin">Geraldine Cancel-Tassin</name><affiliation><nlm:affiliation>CeRePP, Tenon Hospital, 75020 Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Cussenot, Olivier" sort="Cussenot, Olivier" uniqKey="Cussenot O" first="Olivier" last="Cussenot">Olivier Cussenot</name><affiliation><nlm:affiliation>CeRePP, Tenon Hospital, 75020 Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation><nlm:affiliation>Centre de Recherche en Épidémiologie et Santé des Populations (CESP, Inserm U1018), Université Paris-Saclay, UPS, UVSQ, Gustave Roussy, 94805 Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation><nlm:affiliation>Department of Epidemiology, German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke, 14558 Nuthetal, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation><nlm:affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation><nlm:affiliation>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, 9037 Tromsø, Norway.</nlm:affiliation></affiliation></author><author><name sortKey="Ljungberg, Borje" sort="Ljungberg, Borje" uniqKey="Ljungberg B" first="Borje" last="Ljungberg">Borje Ljungberg</name><affiliation><nlm:affiliation>Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, 901 85 Umeå, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Sitaram, Raviprakash T" sort="Sitaram, Raviprakash T" uniqKey="Sitaram R" first="Raviprakash T" last="Sitaram">Raviprakash T. Sitaram</name><affiliation><nlm:affiliation>Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, 901 85 Umeå, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Bruinsma, Fiona" sort="Bruinsma, Fiona" uniqKey="Bruinsma F" first="Fiona" last="Bruinsma">Fiona Bruinsma</name><affiliation><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Jordan, Susan J" sort="Jordan, Susan J" uniqKey="Jordan S" first="Susan J" last="Jordan">Susan J. Jordan</name><affiliation><nlm:affiliation>QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation><nlm:affiliation>Centre de Recherche en Épidémiologie et Santé des Populations (CESP, Inserm U1018), Université Paris-Saclay, UPS, UVSQ, Gustave Roussy, 94805 Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Winship, Ingrid" sort="Winship, Ingrid" uniqKey="Winship I" first="Ingrid" last="Winship">Ingrid Winship</name><affiliation><nlm:affiliation>Department of Medicine, The University of Melbourne, Melbourne, Victoria 3010, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><affiliation><nlm:affiliation>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway.</nlm:affiliation></affiliation></author><author><name sortKey="Vatten, Lars J" sort="Vatten, Lars J" uniqKey="Vatten L" first="Lars J" last="Vatten">Lars J. Vatten</name><affiliation><nlm:affiliation>Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim 7491, Norway.</nlm:affiliation></affiliation></author><author><name sortKey="Fletcher, Tony" sort="Fletcher, Tony" uniqKey="Fletcher T" first="Tony" last="Fletcher">Tony Fletcher</name><affiliation><nlm:affiliation>London School of Hygiene and Tropical Medicine, University of London, London WC1H 9SH, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Koppova, Kvetoslava" sort="Koppova, Kvetoslava" uniqKey="Koppova K" first="Kvetoslava" last="Koppova">Kvetoslava Koppova</name><affiliation><nlm:affiliation>Regional Authority of Public Health in Banska Bystrica, 975 56 Banska Bystrica, Slovakia.</nlm:affiliation></affiliation></author><author><name sortKey="Larsson, Susanna C" sort="Larsson, Susanna C" uniqKey="Larsson S" first="Susanna C" last="Larsson">Susanna C. Larsson</name><affiliation><nlm:affiliation>Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name><affiliation><nlm:affiliation>Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Banks, Rosamonde E" sort="Banks, Rosamonde E" uniqKey="Banks R" first="Rosamonde E" last="Banks">Rosamonde E. Banks</name><affiliation><nlm:affiliation>Leeds Institute of Cancer and Pathology, University of Leeds, Cancer Research Building, St James's University Hospital, Leeds LS9 7TF, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Selby, Peter J" sort="Selby, Peter J" uniqKey="Selby P" first="Peter J" last="Selby">Peter J. Selby</name><affiliation><nlm:affiliation>Leeds Institute of Cancer and Pathology, University of Leeds, Cancer Research Building, St James's University Hospital, Leeds LS9 7TF, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation><nlm:affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Pharoah, Paul" sort="Pharoah, Paul" uniqKey="Pharoah P" first="Paul" last="Pharoah">Paul Pharoah</name><affiliation><nlm:affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Andreotti, Gabriella" sort="Andreotti, Gabriella" uniqKey="Andreotti G" first="Gabriella" last="Andreotti">Gabriella Andreotti</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Freeman, Laura E Beane" sort="Freeman, Laura E Beane" uniqKey="Freeman L" first="Laura E Beane" last="Freeman">Laura E Beane Freeman</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Koutros, Stella" sort="Koutros, Stella" uniqKey="Koutros S" first="Stella" last="Koutros">Stella Koutros</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation><nlm:affiliation>Department of Health, National Institute for Health and Welfare, 00271 Helsinki, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Weinstein, Stephanie" sort="Weinstein, Stephanie" uniqKey="Weinstein S" first="Stephanie" last="Weinstein">Stephanie Weinstein</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Clark, Peter E" sort="Clark, Peter E" uniqKey="Clark P" first="Peter E" last="Clark">Peter E. Clark</name><affiliation><nlm:affiliation>Vanderbilt-Ingram Cancer Center, Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Edwards, Todd L" sort="Edwards, Todd L" uniqKey="Edwards T" first="Todd L" last="Edwards">Todd L. Edwards</name><affiliation><nlm:affiliation>Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37209, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lipworth, Loren" sort="Lipworth, Loren" uniqKey="Lipworth L" first="Loren" last="Lipworth">Loren Lipworth</name><affiliation><nlm:affiliation>Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Gapstur, Susan M" sort="Gapstur, Susan M" uniqKey="Gapstur S" first="Susan M" last="Gapstur">Susan M. Gapstur</name><affiliation><nlm:affiliation>American Cancer Society, Atlanta, Georgia 30303, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Stevens, Victoria L" sort="Stevens, Victoria L" uniqKey="Stevens V" first="Victoria L" last="Stevens">Victoria L. Stevens</name><affiliation><nlm:affiliation>American Cancer Society, Atlanta, Georgia 30303, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Carol, Hallie" sort="Carol, Hallie" uniqKey="Carol H" first="Hallie" last="Carol">Hallie Carol</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Freedman, Matthew L" sort="Freedman, Matthew L" uniqKey="Freedman M" first="Matthew L" last="Freedman">Matthew L. Freedman</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Pomerantz, Mark M" sort="Pomerantz, Mark M" uniqKey="Pomerantz M" first="Mark M" last="Pomerantz">Mark M. Pomerantz</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Cho, Eunyoung" sort="Cho, Eunyoung" uniqKey="Cho E" first="Eunyoung" last="Cho">Eunyoung Cho</name><affiliation><nlm:affiliation>Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Preston, Mark A" sort="Preston, Mark A" uniqKey="Preston M" first="Mark A" last="Preston">Mark A. Preston</name><affiliation><nlm:affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wilson, Kathryn M" sort="Wilson, Kathryn M" uniqKey="Wilson K" first="Kathryn M" last="Wilson">Kathryn M. Wilson</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Michael Gaziano, J" sort="Michael Gaziano, J" uniqKey="Michael Gaziano J" first="J" last="Michael Gaziano">J. Michael Gaziano</name><affiliation><nlm:affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D" last="Sesso">Howard D. Sesso</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Black, Amanda" sort="Black, Amanda" uniqKey="Black A" first="Amanda" last="Black">Amanda Black</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Freedman, Neal D" sort="Freedman, Neal D" uniqKey="Freedman N" first="Neal D" last="Freedman">Neal D. Freedman</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Huang, Wen Yi" sort="Huang, Wen Yi" uniqKey="Huang W" first="Wen-Yi" last="Huang">Wen-Yi Huang</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Anema, John G" sort="Anema, John G" uniqKey="Anema J" first="John G" last="Anema">John G. Anema</name><affiliation><nlm:affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Kahnoski, Richard J" sort="Kahnoski, Richard J" uniqKey="Kahnoski R" first="Richard J" last="Kahnoski">Richard J. Kahnoski</name><affiliation><nlm:affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lane, Brian R" sort="Lane, Brian R" uniqKey="Lane B" first="Brian R" last="Lane">Brian R. Lane</name><affiliation><nlm:affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Noyes, Sabrina L" sort="Noyes, Sabrina L" uniqKey="Noyes S" first="Sabrina L" last="Noyes">Sabrina L. Noyes</name><affiliation><nlm:affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Petillo, David" sort="Petillo, David" uniqKey="Petillo D" first="David" last="Petillo">David Petillo</name><affiliation><nlm:affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Teh, Bin Tean" sort="Teh, Bin Tean" uniqKey="Teh B" first="Bin Tean" last="Teh">Bin Tean Teh</name><affiliation><nlm:affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation><nlm:affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:affiliation></affiliation></author><author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><affiliation><nlm:affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Anderson, Garnet L" sort="Anderson, Garnet L" uniqKey="Anderson G" first="Garnet L" last="Anderson">Garnet L. Anderson</name><affiliation><nlm:affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Johnson, Lisa" sort="Johnson, Lisa" uniqKey="Johnson L" first="Lisa" last="Johnson">Lisa Johnson</name><affiliation><nlm:affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Luo, Juhua" sort="Luo, Juhua" uniqKey="Luo J" first="Juhua" last="Luo">Juhua Luo</name><affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health Indiana University Bloomington, Bloomington, Indiana 47405, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Buring, Julie" sort="Buring, Julie" uniqKey="Buring J" first="Julie" last="Buring">Julie Buring</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Lee, I Min" sort="Lee, I Min" uniqKey="Lee I" first="I-Min" last="Lee">I-Min Lee</name><affiliation><nlm:affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chow, Wong Ho" sort="Chow, Wong Ho" uniqKey="Chow W" first="Wong-Ho" last="Chow">Wong-Ho Chow</name><affiliation><nlm:affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Moore, Lee E" sort="Moore, Lee E" uniqKey="Moore L" first="Lee E" last="Moore">Lee E. Moore</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wood, Christopher" sort="Wood, Christopher" uniqKey="Wood C" first="Christopher" last="Wood">Christopher Wood</name><affiliation><nlm:affiliation>Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Eisen, Timothy" sort="Eisen, Timothy" uniqKey="Eisen T" first="Timothy" last="Eisen">Timothy Eisen</name><affiliation><nlm:affiliation>Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Henrion, Marc" sort="Henrion, Marc" uniqKey="Henrion M" first="Marc" last="Henrion">Marc Henrion</name><affiliation><nlm:affiliation>Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Larkin, James" sort="Larkin, James" uniqKey="Larkin J" first="James" last="Larkin">James Larkin</name><affiliation><nlm:affiliation>Medical Oncology, Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Barman, Poulami" sort="Barman, Poulami" uniqKey="Barman P" first="Poulami" last="Barman">Poulami Barman</name><affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Leibovich, Bradley C" sort="Leibovich, Bradley C" uniqKey="Leibovich B" first="Bradley C" last="Leibovich">Bradley C. Leibovich</name><affiliation><nlm:affiliation>Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55902, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Choueiri, Toni K" sort="Choueiri, Toni K" uniqKey="Choueiri T" first="Toni K" last="Choueiri">Toni K. Choueiri</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mark Lathrop, G" sort="Mark Lathrop, G" uniqKey="Mark Lathrop G" first="G" last="Mark Lathrop">G. Mark Lathrop</name><affiliation><nlm:affiliation>McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada H3A 0G1.</nlm:affiliation></affiliation></author><author><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Deleuze, Jean Francois" sort="Deleuze, Jean Francois" uniqKey="Deleuze J" first="Jean-Francois" last="Deleuze">Jean-Francois Deleuze</name><affiliation><nlm:affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</nlm:affiliation></affiliation></author><author><name sortKey="Mckay, James D" sort="Mckay, James D" uniqKey="Mckay J" first="James D" last="Mckay">James D. Mckay</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Parker, Alexander S" sort="Parker, Alexander S" uniqKey="Parker A" first="Alexander S" last="Parker">Alexander S. Parker</name><affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Jacksonville, Florida 32224, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wu, Xifeng" sort="Wu, Xifeng" uniqKey="Wu X" first="Xifeng" last="Wu">Xifeng Wu</name><affiliation><nlm:affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Houlston, Richard S" sort="Houlston, Richard S" uniqKey="Houlston R" first="Richard S" last="Houlston">Richard S. Houlston</name><affiliation><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name><affiliation><nlm:affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Nature communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10(-10)), 3p22.1 (rs67311347, P=2.5 × 10(-8)), 3q26.2 (rs10936602, P=8.8 × 10(-9)), 8p21.3 (rs2241261, P=5.8 × 10(-9)), 10q24.33-q25.1 (rs11813268, P=3.9 × 10(-8)), 11q22.3 (rs74911261, P=2.1 × 10(-10)) and 14q24.2 (rs4903064, P=2.2 × 10(-24)). Expression quantitative trait analyses suggest plausible candidate genes at these regions that may contribute to RCC susceptibility.</div></front></TEI><pubmed><MedlineCitation Status="In-Data-Review" Owner="NLM"><PMID Version="1">28598434</PMID><DateCreated><Year>2017</Year><Month>06</Month><Day>09</Day></DateCreated><DateRevised><Year>2017</Year><Month>07</Month><Day>14</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2041-1723</ISSN><JournalIssue CitedMedium="Internet"><Volume>8</Volume><PubDate><Year>2017</Year><Month>Jun</Month><Day>09</Day></PubDate></JournalIssue><Title>Nature communications</Title><ISOAbbreviation>Nat Commun</ISOAbbreviation></Journal><ArticleTitle>Genome-wide association study identifies multiple risk loci for renal cell carcinoma.</ArticleTitle><Pagination><MedlinePgn>15724</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/ncomms15724</ELocationID><Abstract><AbstractText>Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10(-10)), 3p22.1 (rs67311347, P=2.5 × 10(-8)), 3q26.2 (rs10936602, P=8.8 × 10(-9)), 8p21.3 (rs2241261, P=5.8 × 10(-9)), 10q24.33-q25.1 (rs11813268, P=3.9 × 10(-8)), 11q22.3 (rs74911261, P=2.1 × 10(-10)) and 14q24.2 (rs4903064, P=2.2 × 10(-24)). Expression quantitative trait analyses suggest plausible candidate genes at these regions that may contribute to RCC susceptibility.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Scelo</LastName><ForeName>Ghislaine</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Purdue</LastName><ForeName>Mark P</ForeName><Initials>MP</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brown</LastName><ForeName>Kevin M</ForeName><Initials>KM</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johansson</LastName><ForeName>Mattias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Zhaoming</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eckel-Passow</LastName><ForeName>Jeanette E</ForeName><Initials>JE</Initials><AffiliationInfo><Affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ye</LastName><ForeName>Yuanqing</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hofmann</LastName><ForeName>Jonathan N</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Choi</LastName><ForeName>Jiyeon</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Foll</LastName><ForeName>Matthieu</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gaborieau</LastName><ForeName>Valerie</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Machiela</LastName><ForeName>Mitchell J</ForeName><Initials>MJ</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-6538-9705</Identifier><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Colli</LastName><ForeName>Leandro M</ForeName><Initials>LM</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Peng</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sampson</LastName><ForeName>Joshua N</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abedi-Ardekani</LastName><ForeName>Behnoush</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Besse</LastName><ForeName>Celine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blanche</LastName><ForeName>Helene</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain, 75010 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boland</LastName><ForeName>Anne</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Burdette</LastName><ForeName>Laurie</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chabrier</LastName><ForeName>Amelie</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Durand</LastName><ForeName>Geoffroy</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Le Calvez-Kelm</LastName><ForeName>Florence</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prokhortchouk</LastName><ForeName>Egor</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Center 'Bioengineering' of the Russian Academy of Sciences, Moscow 117312, Russia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Kurchatov Scientific Center, Moscow 123182, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Robinot</LastName><ForeName>Nivonirina</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Skryabin</LastName><ForeName>Konstantin G</ForeName><Initials>KG</Initials><AffiliationInfo><Affiliation>Center 'Bioengineering' of the Russian Academy of Sciences, Moscow 117312, Russia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Kurchatov Scientific Center, Moscow 123182, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wozniak</LastName><ForeName>Magdalena B</ForeName><Initials>MB</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yeager</LastName><ForeName>Meredith</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Basta-Jovanovic</LastName><ForeName>Gordana</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Institute of Pathology, School of Medicine, University of Belgrade, 11000 Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dzamic</LastName><ForeName>Zoran</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Clinical Center of Serbia (KCS), Clinic of Urology, University of Belgrade-Faculty of Medicine, 11000 Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Foretova</LastName><ForeName>Lenka</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Holcatova</LastName><ForeName>Ivana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>2nd Faculty of Medicine, Institute of Public Health and Preventive Medicine, Charles University, 150 06 Prague 5, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Janout</LastName><ForeName>Vladimir</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Preventive Medicine, Faculty of Medicine, Palacky University, 775 15 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mates</LastName><ForeName>Dana</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>National Institute of Public Health, 050463 Bucharest, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mukeriya</LastName><ForeName>Anush</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Russian N.N. Blokhin Cancer Research Centre, Moscow 115478, Russian Federation.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rascu</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Carol Davila University of Medicine and Pharmacy, Th. Burghele Hospital, 050659 Bucharest, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zaridze</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Russian N.N. Blokhin Cancer Research Centre, Moscow 115478, Russian Federation.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bencko</LastName><ForeName>Vladimir</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>First Faculty of Medicine, Institute of Hygiene and Epidemiology, Charles University, 128 00 Prague 2, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cybulski</LastName><ForeName>Cezary</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, 70-204 Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fabianova</LastName><ForeName>Eleonora</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Regional Authority of Public Health in Banska Bystrica, 975 56 Banska Bystrica, Slovakia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jinga</LastName><ForeName>Viorel</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Carol Davila University of Medicine and Pharmacy, Th. Burghele Hospital, 050659 Bucharest, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lissowska</LastName><ForeName>Jolanta</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>The M Sklodowska-Curie Cancer Center and Institute of Oncology, 02-034 Warsaw, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lubinski</LastName><ForeName>Jan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, 70-204 Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Navratilova</LastName><ForeName>Marie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudnai</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>National Public Health Center, National Directorate of Environmental Health, 1097 Budapest, Hungary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Szeszenia-Dabrowska</LastName><ForeName>Neonila</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Institute of Occupational Medicine, 91-348 Lodz, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benhamou</LastName><ForeName>Simone</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Université Paris Diderot, INSERM, Unité Variabilité Génétique et Maladies Humaines, 75010 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cancel-Tassin</LastName><ForeName>Geraldine</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>CeRePP, Tenon Hospital, 75020 Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>UPMC Univ Paris 06 GRC n°5, 75013 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cussenot</LastName><ForeName>Olivier</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>CeRePP, Tenon Hospital, 75020 Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>UPMC Univ Paris 06 GRC n°5, 75013 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baglietto</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Centre de Recherche en Épidémiologie et Santé des Populations (CESP, Inserm U1018), Université Paris-Saclay, UPS, UVSQ, Gustave Roussy, 94805 Villejuif, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boeing</LastName><ForeName>Heiner</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke, 14558 Nuthetal, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khaw</LastName><ForeName>Kay-Tee</ForeName><Initials>KT</Initials><AffiliationInfo><Affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weiderpass</LastName><ForeName>Elisabete</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, 9037 Tromsø, Norway.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, 0304 Oslo, Norway.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Genetic Epidemiology Group, Folkhälsan Research Center, 00250 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ljungberg</LastName><ForeName>Borje</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, 901 85 Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sitaram</LastName><ForeName>Raviprakash T</ForeName><Initials>RT</Initials><AffiliationInfo><Affiliation>Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, 901 85 Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bruinsma</LastName><ForeName>Fiona</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jordan</LastName><ForeName>Susan J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>QIMR Berghofer Medical Research Institute, Herston, Queensland 4006, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>School of Public Health, The University of Queensland, Brisbane, Queensland 4072, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Severi</LastName><ForeName>Gianluca</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Centre de Recherche en Épidémiologie et Santé des Populations (CESP, Inserm U1018), Université Paris-Saclay, UPS, UVSQ, Gustave Roussy, 94805 Villejuif, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, Victoria 3053, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Human Genetics Foundation (HuGeF), 10126 Torino, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Winship</LastName><ForeName>Ingrid</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Medicine, The University of Melbourne, Melbourne, Victoria 3010, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Genetic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hveem</LastName><ForeName>Kristian</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vatten</LastName><ForeName>Lars J</ForeName><Initials>LJ</Initials><AffiliationInfo><Affiliation>Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim 7491, Norway.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fletcher</LastName><ForeName>Tony</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>London School of Hygiene and Tropical Medicine, University of London, London WC1H 9SH, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koppova</LastName><ForeName>Kvetoslava</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Regional Authority of Public Health in Banska Bystrica, 975 56 Banska Bystrica, Slovakia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Larsson</LastName><ForeName>Susanna C</ForeName><Initials>SC</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-0118-0341</Identifier><AffiliationInfo><Affiliation>Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wolk</LastName><ForeName>Alicja</ForeName><Initials>A</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-7387-6845</Identifier><AffiliationInfo><Affiliation>Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Banks</LastName><ForeName>Rosamonde E</ForeName><Initials>RE</Initials><AffiliationInfo><Affiliation>Leeds Institute of Cancer and Pathology, University of Leeds, Cancer Research Building, St James's University Hospital, Leeds LS9 7TF, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Selby</LastName><ForeName>Peter J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Leeds Institute of Cancer and Pathology, University of Leeds, Cancer Research Building, St James's University Hospital, Leeds LS9 7TF, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Easton</LastName><ForeName>Douglas F</ForeName><Initials>DF</Initials><AffiliationInfo><Affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pharoah</LastName><ForeName>Paul</ForeName><Initials>P</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-8494-732X</Identifier><AffiliationInfo><Affiliation>Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Andreotti</LastName><ForeName>Gabriella</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Freeman</LastName><ForeName>Laura E Beane</ForeName><Initials>LEB</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koutros</LastName><ForeName>Stella</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Albanes</LastName><ForeName>Demetrius</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Männistö</LastName><ForeName>Satu</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Health, National Institute for Health and Welfare, 00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weinstein</LastName><ForeName>Stephanie</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Clark</LastName><ForeName>Peter E</ForeName><Initials>PE</Initials><AffiliationInfo><Affiliation>Vanderbilt-Ingram Cancer Center, Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Edwards</LastName><ForeName>Todd L</ForeName><Initials>TL</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-4318-6119</Identifier><AffiliationInfo><Affiliation>Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37209, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lipworth</LastName><ForeName>Loren</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gapstur</LastName><ForeName>Susan M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>American Cancer Society, Atlanta, Georgia 30303, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stevens</LastName><ForeName>Victoria L</ForeName><Initials>VL</Initials><AffiliationInfo><Affiliation>American Cancer Society, Atlanta, Georgia 30303, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Carol</LastName><ForeName>Hallie</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Freedman</LastName><ForeName>Matthew L</ForeName><Initials>ML</Initials><AffiliationInfo><Affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pomerantz</LastName><ForeName>Mark M</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cho</LastName><ForeName>Eunyoung</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kraft</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Preston</LastName><ForeName>Mark A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wilson</LastName><ForeName>Kathryn M</ForeName><Initials>KM</Initials><AffiliationInfo><Affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Michael Gaziano</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sesso</LastName><ForeName>Howard D</ForeName><Initials>HD</Initials><AffiliationInfo><Affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Black</LastName><ForeName>Amanda</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Freedman</LastName><ForeName>Neal D</ForeName><Initials>ND</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huang</LastName><ForeName>Wen-Yi</ForeName><Initials>WY</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anema</LastName><ForeName>John G</ForeName><Initials>JG</Initials><AffiliationInfo><Affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kahnoski</LastName><ForeName>Richard J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lane</LastName><ForeName>Brian R</ForeName><Initials>BR</Initials><AffiliationInfo><Affiliation>Division of Urology, Spectrum Health, Grand Rapids, Michigan 49503, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>College of Human Medicine, Michigan State University, Grand Rapids, Michigan 49503, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Noyes</LastName><ForeName>Sabrina L</ForeName><Initials>SL</Initials><AffiliationInfo><Affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Petillo</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Teh</LastName><ForeName>Bin Tean</ForeName><Initials>BT</Initials><AffiliationInfo><Affiliation>Van Andel Research Institute, Center for Cancer Genomics and Quantitative Biology, Grand Rapids, Michigan 49503, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peters</LastName><ForeName>Ulrike</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>White</LastName><ForeName>Emily</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anderson</LastName><ForeName>Garnet L</ForeName><Initials>GL</Initials><AffiliationInfo><Affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johnson</LastName><ForeName>Lisa</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luo</LastName><ForeName>Juhua</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, School of Public Health Indiana University Bloomington, Bloomington, Indiana 47405, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buring</LastName><ForeName>Julie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>I-Min</ForeName><Initials>IM</Initials><AffiliationInfo><Affiliation>Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brigham and Women's Hospital and VA Boston, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chow</LastName><ForeName>Wong-Ho</ForeName><Initials>WH</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moore</LastName><ForeName>Lee E</ForeName><Initials>LE</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wood</LastName><ForeName>Christopher</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eisen</LastName><ForeName>Timothy</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Henrion</LastName><ForeName>Marc</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Larkin</LastName><ForeName>James</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Medical Oncology, Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barman</LastName><ForeName>Poulami</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leibovich</LastName><ForeName>Bradley C</ForeName><Initials>BC</Initials><AffiliationInfo><Affiliation>Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55902, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Choueiri</LastName><ForeName>Toni K</ForeName><Initials>TK</Initials><AffiliationInfo><Affiliation>Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mark Lathrop</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada H3A 0G1.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rothman</LastName><ForeName>Nathaniel</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Deleuze</LastName><ForeName>Jean-Francois</ForeName><Initials>JF</Initials><AffiliationInfo><Affiliation>Centre National de Genotypage, Institut de Genomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, 91057 Evry, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain, 75010 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McKay</LastName><ForeName>James D</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parker</LastName><ForeName>Alexander S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Department of Health Sciences Research, Mayo Clinic, Jacksonville, Florida 32224, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wu</LastName><ForeName>Xifeng</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Houlston</LastName><ForeName>Richard S</ForeName><Initials>RS</Initials><AffiliationInfo><Affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Molecular Pathology, The Institute of Cancer Research, London SW7 3RP, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brennan</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>International Agency for Research on Cancer (IARC), 69008 Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chanock</LastName><ForeName>Stephen J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>U01 CA155309</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>06</Month><Day>09</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Nat Commun</MedlineTA><NlmUniqueID>101528555</NlmUniqueID><ISSNLinking>2041-1723</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2013 Oct;45(10):1221-5</RefSource><PMID Version="1">23955597</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2015 Feb 19;518(7539):317-30</RefSource><PMID Version="1">25693563</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2011 Jan;43(1):60-5</RefSource><PMID Version="1">21131975</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2010 Jul;42(7):565-9</RefSource><PMID 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