Range and Heterogeneity of Outcomes in Randomized Trials of Pediatric Chronic Kidney Disease.
Identifieur interne : 000910 ( PubMed/Corpus ); précédent : 000909; suivant : 000911Range and Heterogeneity of Outcomes in Randomized Trials of Pediatric Chronic Kidney Disease.
Auteurs : Lauren S H. Chong ; Benedicte Sautenet ; Allison Tong ; Camilla S. Hanson ; Susan Samuel ; Michael Zappitelli ; Allison Dart ; Susan Furth ; Allison A. Eddy ; Jaap Groothoff ; Nicholas J A. Webb ; Hui-Kim Yap ; Detlef Bockenhauer ; Aditi Sinha ; Stephen I. Alexander ; Stuart L. Goldstein ; Debbie S. Gipson ; Gayathri Raman ; Jonathan C. CraigSource :
- The Journal of pediatrics [ 1097-6833 ] ; 2017.
English descriptors
- KwdEn :
- MESH :
Abstract
To determine the range and heterogeneity of outcomes reported in randomized controlled trials of interventions for children with chronic kidney disease (CKD).
DOI: 10.1016/j.jpeds.2017.03.034
PubMed: 28449820
Links to Exploration step
pubmed:28449820Le document en format XML
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Chong</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Sautenet, Benedicte" sort="Sautenet, Benedicte" uniqKey="Sautenet B" first="Benedicte" last="Sautenet">Benedicte Sautenet</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia; University Francois Rabelais, Tours, France; Department of Nephrology and Clinical Immunology, Tours Hospital, Tours, France; INSERM (U1153), Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Tong, Allison" sort="Tong, Allison" uniqKey="Tong A" first="Allison" last="Tong">Allison Tong</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia. Electronic address: allison.tong@sydney.edu.au.</nlm:affiliation></affiliation></author><author><name sortKey="Hanson, Camilla S" sort="Hanson, Camilla S" uniqKey="Hanson C" first="Camilla S" last="Hanson">Camilla S. Hanson</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Samuel, Susan" sort="Samuel, Susan" uniqKey="Samuel S" first="Susan" last="Samuel">Susan Samuel</name><affiliation><nlm:affiliation>Department of Pediatrics, Section of Nephrology, University of Calgary, Calgary, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Zappitelli, Michael" sort="Zappitelli, Michael" uniqKey="Zappitelli M" first="Michael" last="Zappitelli">Michael Zappitelli</name><affiliation><nlm:affiliation>Department of Pediatrics, Division of Pediatric Nephrology, Montreal Children's Hospital, McGill University Health Centre, McGill University, Montreal, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Dart, Allison" sort="Dart, Allison" uniqKey="Dart A" first="Allison" last="Dart">Allison Dart</name><affiliation><nlm:affiliation>Department of Pediatrics and Child Health, The Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Furth, Susan" sort="Furth, Susan" uniqKey="Furth S" first="Susan" last="Furth">Susan Furth</name><affiliation><nlm:affiliation>Departments of Pediatrics and Epidemiology, Perelman School of Medicine, Division of Nephrology, The Children's Hospital of Philadelphia, Philadelphia, PA.</nlm:affiliation></affiliation></author><author><name sortKey="Eddy, Allison A" sort="Eddy, Allison A" uniqKey="Eddy A" first="Allison A" last="Eddy">Allison A. Eddy</name><affiliation><nlm:affiliation>Department of Pediatrics, University of British Columbia and the British Columbia Children's Hospital, Vancouver, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Groothoff, Jaap" sort="Groothoff, Jaap" uniqKey="Groothoff J" first="Jaap" last="Groothoff">Jaap Groothoff</name><affiliation><nlm:affiliation>Department of Pediatric Nephrology, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Webb, Nicholas J A" sort="Webb, Nicholas J A" uniqKey="Webb N" first="Nicholas J A" last="Webb">Nicholas J A. Webb</name><affiliation><nlm:affiliation>Department of Pediatric Nephrology and National Institute for Health Research/Wellcome Trust Clinical Research Facility, University of Manchester, Manchester Academic Health Science Centre, Royal Manchester Children's Hospital, Manchester, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Yap, Hui Kim" sort="Yap, Hui Kim" uniqKey="Yap H" first="Hui-Kim" last="Yap">Hui-Kim Yap</name><affiliation><nlm:affiliation>Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation></affiliation></author><author><name sortKey="Bockenhauer, Detlef" sort="Bockenhauer, Detlef" uniqKey="Bockenhauer D" first="Detlef" last="Bockenhauer">Detlef Bockenhauer</name><affiliation><nlm:affiliation>University College London Centre for Nephrology, Great Ormond Street Hospital for Children National Health Service Foundation Trust, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Sinha, Aditi" sort="Sinha, Aditi" uniqKey="Sinha A" first="Aditi" last="Sinha">Aditi Sinha</name><affiliation><nlm:affiliation>Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, India.</nlm:affiliation></affiliation></author><author><name sortKey="Alexander, Stephen I" sort="Alexander, Stephen I" uniqKey="Alexander S" first="Stephen I" last="Alexander">Stephen I. Alexander</name><affiliation><nlm:affiliation>Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Goldstein, Stuart L" sort="Goldstein, Stuart L" uniqKey="Goldstein S" first="Stuart L" last="Goldstein">Stuart L. Goldstein</name><affiliation><nlm:affiliation>Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.</nlm:affiliation></affiliation></author><author><name sortKey="Gipson, Debbie S" sort="Gipson, Debbie S" uniqKey="Gipson D" first="Debbie S" last="Gipson">Debbie S. Gipson</name><affiliation><nlm:affiliation>Department of Pediatrics, School of Medicine, University of Michigan, Ann Arbor, MI.</nlm:affiliation></affiliation></author><author><name sortKey="Raman, Gayathri" sort="Raman, Gayathri" uniqKey="Raman G" first="Gayathri" last="Raman">Gayathri Raman</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Craig, Jonathan C" sort="Craig, Jonathan C" uniqKey="Craig J" first="Jonathan C" last="Craig">Jonathan C. Craig</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28449820</idno><idno type="pmid">28449820</idno><idno type="doi">10.1016/j.jpeds.2017.03.034</idno><idno type="wicri:Area/PubMed/Corpus">000910</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000910</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Range and Heterogeneity of Outcomes in Randomized Trials of Pediatric Chronic Kidney Disease.</title><author><name sortKey="Chong, Lauren S H" sort="Chong, Lauren S H" uniqKey="Chong L" first="Lauren S H" last="Chong">Lauren S H. Chong</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Sautenet, Benedicte" sort="Sautenet, Benedicte" uniqKey="Sautenet B" first="Benedicte" last="Sautenet">Benedicte Sautenet</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia; University Francois Rabelais, Tours, France; Department of Nephrology and Clinical Immunology, Tours Hospital, Tours, France; INSERM (U1153), Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Tong, Allison" sort="Tong, Allison" uniqKey="Tong A" first="Allison" last="Tong">Allison Tong</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia. Electronic address: allison.tong@sydney.edu.au.</nlm:affiliation></affiliation></author><author><name sortKey="Hanson, Camilla S" sort="Hanson, Camilla S" uniqKey="Hanson C" first="Camilla S" last="Hanson">Camilla S. Hanson</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Samuel, Susan" sort="Samuel, Susan" uniqKey="Samuel S" first="Susan" last="Samuel">Susan Samuel</name><affiliation><nlm:affiliation>Department of Pediatrics, Section of Nephrology, University of Calgary, Calgary, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Zappitelli, Michael" sort="Zappitelli, Michael" uniqKey="Zappitelli M" first="Michael" last="Zappitelli">Michael Zappitelli</name><affiliation><nlm:affiliation>Department of Pediatrics, Division of Pediatric Nephrology, Montreal Children's Hospital, McGill University Health Centre, McGill University, Montreal, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Dart, Allison" sort="Dart, Allison" uniqKey="Dart A" first="Allison" last="Dart">Allison Dart</name><affiliation><nlm:affiliation>Department of Pediatrics and Child Health, The Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Furth, Susan" sort="Furth, Susan" uniqKey="Furth S" first="Susan" last="Furth">Susan Furth</name><affiliation><nlm:affiliation>Departments of Pediatrics and Epidemiology, Perelman School of Medicine, Division of Nephrology, The Children's Hospital of Philadelphia, Philadelphia, PA.</nlm:affiliation></affiliation></author><author><name sortKey="Eddy, Allison A" sort="Eddy, Allison A" uniqKey="Eddy A" first="Allison A" last="Eddy">Allison A. Eddy</name><affiliation><nlm:affiliation>Department of Pediatrics, University of British Columbia and the British Columbia Children's Hospital, Vancouver, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Groothoff, Jaap" sort="Groothoff, Jaap" uniqKey="Groothoff J" first="Jaap" last="Groothoff">Jaap Groothoff</name><affiliation><nlm:affiliation>Department of Pediatric Nephrology, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Webb, Nicholas J A" sort="Webb, Nicholas J A" uniqKey="Webb N" first="Nicholas J A" last="Webb">Nicholas J A. Webb</name><affiliation><nlm:affiliation>Department of Pediatric Nephrology and National Institute for Health Research/Wellcome Trust Clinical Research Facility, University of Manchester, Manchester Academic Health Science Centre, Royal Manchester Children's Hospital, Manchester, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Yap, Hui Kim" sort="Yap, Hui Kim" uniqKey="Yap H" first="Hui-Kim" last="Yap">Hui-Kim Yap</name><affiliation><nlm:affiliation>Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</nlm:affiliation></affiliation></author><author><name sortKey="Bockenhauer, Detlef" sort="Bockenhauer, Detlef" uniqKey="Bockenhauer D" first="Detlef" last="Bockenhauer">Detlef Bockenhauer</name><affiliation><nlm:affiliation>University College London Centre for Nephrology, Great Ormond Street Hospital for Children National Health Service Foundation Trust, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Sinha, Aditi" sort="Sinha, Aditi" uniqKey="Sinha A" first="Aditi" last="Sinha">Aditi Sinha</name><affiliation><nlm:affiliation>Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, India.</nlm:affiliation></affiliation></author><author><name sortKey="Alexander, Stephen I" sort="Alexander, Stephen I" uniqKey="Alexander S" first="Stephen I" last="Alexander">Stephen I. Alexander</name><affiliation><nlm:affiliation>Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Goldstein, Stuart L" sort="Goldstein, Stuart L" uniqKey="Goldstein S" first="Stuart L" last="Goldstein">Stuart L. Goldstein</name><affiliation><nlm:affiliation>Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.</nlm:affiliation></affiliation></author><author><name sortKey="Gipson, Debbie S" sort="Gipson, Debbie S" uniqKey="Gipson D" first="Debbie S" last="Gipson">Debbie S. Gipson</name><affiliation><nlm:affiliation>Department of Pediatrics, School of Medicine, University of Michigan, Ann Arbor, MI.</nlm:affiliation></affiliation></author><author><name sortKey="Raman, Gayathri" sort="Raman, Gayathri" uniqKey="Raman G" first="Gayathri" last="Raman">Gayathri Raman</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Craig, Jonathan C" sort="Craig, Jonathan C" uniqKey="Craig J" first="Jonathan C" last="Craig">Jonathan C. Craig</name><affiliation><nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation></affiliation></author></analytic><series><title level="j">The Journal of pediatrics</title><idno type="eISSN">1097-6833</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Age Factors</term><term>Blood Pressure</term><term>Child</term><term>Child, Preschool</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Kidney Function Tests</term><term>Outcome Assessment (Health Care)</term><term>Quality of Life</term><term>Randomized Controlled Trials as Topic</term><term>Recurrence</term><term>Renal Insufficiency, Chronic (therapy)</term><term>Young Adult</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Renal Insufficiency, Chronic</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Age Factors</term><term>Blood Pressure</term><term>Child</term><term>Child, Preschool</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Kidney Function Tests</term><term>Outcome Assessment (Health Care)</term><term>Quality of Life</term><term>Randomized Controlled Trials as Topic</term><term>Recurrence</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To determine the range and heterogeneity of outcomes reported in randomized controlled trials of interventions for children with chronic kidney disease (CKD).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28449820</PMID><DateCreated><Year>2017</Year><Month>04</Month><Day>28</Day></DateCreated><DateCompleted><Year>2017</Year><Month>09</Month><Day>06</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>06</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1097-6833</ISSN><JournalIssue CitedMedium="Internet"><Volume>186</Volume><PubDate><Year>2017</Year><Month>Jul</Month></PubDate></JournalIssue><Title>The Journal of pediatrics</Title><ISOAbbreviation>J. Pediatr.</ISOAbbreviation></Journal><ArticleTitle>Range and Heterogeneity of Outcomes in Randomized Trials of Pediatric Chronic Kidney Disease.</ArticleTitle><Pagination><MedlinePgn>110-117.e11</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0022-3476(17)30383-9</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jpeds.2017.03.034</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To determine the range and heterogeneity of outcomes reported in randomized controlled trials of interventions for children with chronic kidney disease (CKD).</AbstractText><AbstractText Label="STUDY DESIGN" NlmCategory="METHODS">The Cochrane Kidney and Transplant Specialized Register was searched to March 2016. Randomized trials involving children across all stages of CKD were selected. All outcome domains and measurements were extracted from included trials. The frequency and characteristics of the outcome domains and measures were evaluated.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">From 205 trials included, 6158 different measurements of 100 different outcome domains were reported, with a median of 22 domains per trial (IQR 13-41). Overall, 52 domains (52%) were surrogate, 38 (38%) were clinical, and 10 (10%) were patient-reported. The 5 most commonly reported domains were blood pressure (76 [37%] trials), relapse/remission (70 [34%]), kidney function (66 [32%]), infection (61 [30%]), and height/pubertal development (51 [25%]). Mortality (14%), cardiovascular disease (4%), and quality of life (1%) were reported infrequently. The 2 most frequently reported outcomes, blood pressure and relapse/remission, had 56 and 81 different outcome measures, respectively.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The outcomes reported in clinical trials involving children with CKD are extremely heterogeneous and are most often surrogate outcomes, rather than clinical and patient-centered outcomes such as cardiovascular disease and quality of life. Efforts to ensure consistent reporting of outcomes that are important to patients and clinicians will improve the value of trials to guide clinical decision-making. In our study, non-English articles were excluded.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chong</LastName><ForeName>Lauren S H</ForeName><Initials>LSH</Initials><AffiliationInfo><Affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sautenet</LastName><ForeName>Benedicte</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia; University Francois Rabelais, Tours, France; Department of Nephrology and Clinical Immunology, Tours Hospital, Tours, France; INSERM (U1153), Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tong</LastName><ForeName>Allison</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia. Electronic address: allison.tong@sydney.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hanson</LastName><ForeName>Camilla S</ForeName><Initials>CS</Initials><AffiliationInfo><Affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Samuel</LastName><ForeName>Susan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, Section of Nephrology, University of Calgary, Calgary, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zappitelli</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, Division of Pediatric Nephrology, Montreal Children's Hospital, McGill University Health Centre, McGill University, Montreal, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dart</LastName><ForeName>Allison</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Pediatrics and Child Health, The Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Furth</LastName><ForeName>Susan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Departments of Pediatrics and Epidemiology, Perelman School of Medicine, Division of Nephrology, The Children's Hospital of Philadelphia, Philadelphia, PA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eddy</LastName><ForeName>Allison A</ForeName><Initials>AA</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University of British Columbia and the British Columbia Children's Hospital, Vancouver, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Groothoff</LastName><ForeName>Jaap</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Pediatric Nephrology, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Webb</LastName><ForeName>Nicholas J A</ForeName><Initials>NJA</Initials><AffiliationInfo><Affiliation>Department of Pediatric Nephrology and National Institute for Health Research/Wellcome Trust Clinical Research Facility, University of Manchester, Manchester Academic Health Science Centre, Royal Manchester Children's Hospital, Manchester, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yap</LastName><ForeName>Hui-Kim</ForeName><Initials>HK</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bockenhauer</LastName><ForeName>Detlef</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>University College London Centre for Nephrology, Great Ormond Street Hospital for Children National Health Service Foundation Trust, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sinha</LastName><ForeName>Aditi</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alexander</LastName><ForeName>Stephen I</ForeName><Initials>SI</Initials><AffiliationInfo><Affiliation>Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goldstein</LastName><ForeName>Stuart L</ForeName><Initials>SL</Initials><AffiliationInfo><Affiliation>Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gipson</LastName><ForeName>Debbie S</ForeName><Initials>DS</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, School of Medicine, University of Michigan, Ann Arbor, MI.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raman</LastName><ForeName>Gayathri</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Craig</LastName><ForeName>Jonathan C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Sydney School of Public Health, The University of Sydney, Sydney, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>04</Month><Day>24</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Pediatr</MedlineTA><NlmUniqueID>0375410</NlmUniqueID><ISSNLinking>0022-3476</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000367" MajorTopicYN="N">Age Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001794" MajorTopicYN="N">Blood Pressure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007231" MajorTopicYN="N">Infant, Newborn</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007677" MajorTopicYN="N">Kidney Function Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017063" MajorTopicYN="Y">Outcome Assessment (Health Care)</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011788" MajorTopicYN="N">Quality of Life</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016032" MajorTopicYN="N">Randomized Controlled Trials as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012008" MajorTopicYN="N">Recurrence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D051436" MajorTopicYN="N">Renal Insufficiency, Chronic</DescriptorName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">children</Keyword><Keyword MajorTopicYN="N">chronic kidney disease</Keyword><Keyword MajorTopicYN="N">outcomes</Keyword><Keyword MajorTopicYN="N">systematic review</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>12</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>02</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>03</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28449820</ArticleId><ArticleId IdType="pii">S0022-3476(17)30383-9</ArticleId><ArticleId IdType="doi">10.1016/j.jpeds.2017.03.034</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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|area= AustralieFrV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:28449820
|texte= Range and Heterogeneity of Outcomes in Randomized Trials of Pediatric Chronic Kidney Disease.
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Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:28449820" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |