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Influenza epidemiology and immunization during pregnancy: Final report of a World Health Organization working group.

Identifieur interne : 000290 ( PubMed/Corpus ); précédent : 000289; suivant : 000291

Influenza epidemiology and immunization during pregnancy: Final report of a World Health Organization working group.

Auteurs : Deshayne B. Fell ; Eduardo Azziz-Baumgartner ; Michael G. Baker ; Maneesh Batra ; Julien Beauté ; Philippe Beutels ; Niranjan Bhat ; Zulfiqar A. Bhutta ; Cheryl Cohen ; Bremen De Mucio ; Bradford D. Gessner ; Michael G. Gravett ; Mark A. Katz ; Marian Knight ; Vernon J. Lee ; Mark Loeb ; Johannes M. Luteijn ; Helen Marshall ; Harish Nair ; Kevin Pottie ; Rehana A. Salam ; David A. Savitz ; Suzanne J. Serruya ; Becky Skidmore ; Justin R. Ortiz

Source :

RBID : pubmed:28867508

Abstract

From 2014 to 2017, the World Health Organization convened a working group to evaluate influenza disease burden and vaccine efficacy to inform estimates of maternal influenza immunization program impact. The group evaluated existing systematic reviews and relevant primary studies, and conducted four new systematic reviews. There was strong evidence that maternal influenza immunization prevented influenza illness in pregnant women and their infants, although data on severe illness prevention were lacking. The limited number of studies reporting influenza incidence in pregnant women and infants under six months had highly variable estimates and underrepresented low- and middle-income countries. The evidence that maternal influenza immunization reduces the risk of adverse birth outcomes was conflicting, and many observational studies were subject to substantial bias. The lack of scientific clarity regarding disease burden or magnitude of vaccine efficacy against severe illness poses challenges for robust estimation of the potential impact of maternal influenza immunization programs.

DOI: 10.1016/j.vaccine.2017.08.037
PubMed: 28867508

Links to Exploration step

pubmed:28867508

Le document en format XML

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<name sortKey="Beaute, Julien" sort="Beaute, Julien" uniqKey="Beaute J" first="Julien" last="Beauté">Julien Beauté</name>
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<nlm:affiliation>Agence de Médecine Préventive, France. Electronic address: bgessner@aamp.org.</nlm:affiliation>
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<name sortKey="Gravett, Michael G" sort="Gravett, Michael G" uniqKey="Gravett M" first="Michael G" last="Gravett">Michael G. Gravett</name>
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<nlm:affiliation>Department of Obstetrics and Gynecology, University of Washington, USA. Electronic address: gravettm@uw.edu.</nlm:affiliation>
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<name sortKey="Katz, Mark A" sort="Katz, Mark A" uniqKey="Katz M" first="Mark A" last="Katz">Mark A. Katz</name>
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<name sortKey="Knight, Marian" sort="Knight, Marian" uniqKey="Knight M" first="Marian" last="Knight">Marian Knight</name>
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<name sortKey="Loeb, Mark" sort="Loeb, Mark" uniqKey="Loeb M" first="Mark" last="Loeb">Mark Loeb</name>
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<name sortKey="Marshall, Helen" sort="Marshall, Helen" uniqKey="Marshall H" first="Helen" last="Marshall">Helen Marshall</name>
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<name sortKey="Nair, Harish" sort="Nair, Harish" uniqKey="Nair H" first="Harish" last="Nair">Harish Nair</name>
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<nlm:affiliation>Independent Information Specialist, Canada. Electronic address: bskidmore@rogers.com.</nlm:affiliation>
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<name sortKey="Ortiz, Justin R" sort="Ortiz, Justin R" uniqKey="Ortiz J" first="Justin R" last="Ortiz">Justin R. Ortiz</name>
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<name sortKey="Azziz Baumgartner, Eduardo" sort="Azziz Baumgartner, Eduardo" uniqKey="Azziz Baumgartner E" first="Eduardo" last="Azziz-Baumgartner">Eduardo Azziz-Baumgartner</name>
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<nlm:affiliation>Influenza Division, Centers for Disease Control and Prevention, USA. Electronic address: eha9@cdc.gov.</nlm:affiliation>
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<nlm:affiliation>Department of Public Health, University of Otago, New Zealand. Electronic address: michael.baker@otago.ac.nz.</nlm:affiliation>
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<name sortKey="Batra, Maneesh" sort="Batra, Maneesh" uniqKey="Batra M" first="Maneesh" last="Batra">Maneesh Batra</name>
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<nlm:affiliation>Department of Pediatrics-Neonatology, University of Washington School of Medicine, USA. Electronic address: maneesh.batra@seattlechildrens.org.</nlm:affiliation>
</affiliation>
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<name sortKey="Beaute, Julien" sort="Beaute, Julien" uniqKey="Beaute J" first="Julien" last="Beauté">Julien Beauté</name>
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<nlm:affiliation>European Centre for Disease Prevention and Control (ECDC), Sweden. Electronic address: julien.beaute@ecdc.europa.eu.</nlm:affiliation>
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<name sortKey="Beutels, Philippe" sort="Beutels, Philippe" uniqKey="Beutels P" first="Philippe" last="Beutels">Philippe Beutels</name>
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<nlm:affiliation>Centre for Health Economics Research & Modeling Infectious Diseases (CHERMID), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Belgium. Electronic address: philippe.beutels@uantwerpen.be.</nlm:affiliation>
</affiliation>
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<name sortKey="Bhat, Niranjan" sort="Bhat, Niranjan" uniqKey="Bhat N" first="Niranjan" last="Bhat">Niranjan Bhat</name>
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<nlm:affiliation>Center for Vaccine Innovation and Access, PATH, USA. Electronic address: nbhat@path.org.</nlm:affiliation>
</affiliation>
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<name sortKey="Bhutta, Zulfiqar A" sort="Bhutta, Zulfiqar A" uniqKey="Bhutta Z" first="Zulfiqar A" last="Bhutta">Zulfiqar A. Bhutta</name>
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<nlm:affiliation>Centre for Global Child Health, Hospital for Sick Children, Canada; Center of Excellence in Women & Child Health, The Aga Khan University, Pakistan. Electronic address: Zulfiqar.bhutta@sickkkids.ca.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cohen, Cheryl" sort="Cohen, Cheryl" uniqKey="Cohen C" first="Cheryl" last="Cohen">Cheryl Cohen</name>
<affiliation>
<nlm:affiliation>National Institute for Communicable Diseases, National Health Laboratory Service, South Africa; School of Public Health, University of the Witwatersrand, South Africa. Electronic address: cherylc@nicd.ac.za.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="De Mucio, Bremen" sort="De Mucio, Bremen" uniqKey="De Mucio B" first="Bremen" last="De Mucio">Bremen De Mucio</name>
<affiliation>
<nlm:affiliation>Latin American Center for Perinatology, Women and Reproductive Health, Panamerican Health Organization, Uruguay. Electronic address: demuciob@paho.org.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gessner, Bradford D" sort="Gessner, Bradford D" uniqKey="Gessner B" first="Bradford D" last="Gessner">Bradford D. Gessner</name>
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<nlm:affiliation>Agence de Médecine Préventive, France. Electronic address: bgessner@aamp.org.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gravett, Michael G" sort="Gravett, Michael G" uniqKey="Gravett M" first="Michael G" last="Gravett">Michael G. Gravett</name>
<affiliation>
<nlm:affiliation>Department of Obstetrics and Gynecology, University of Washington, USA. Electronic address: gravettm@uw.edu.</nlm:affiliation>
</affiliation>
</author>
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<name sortKey="Katz, Mark A" sort="Katz, Mark A" uniqKey="Katz M" first="Mark A" last="Katz">Mark A. Katz</name>
<affiliation>
<nlm:affiliation>Medical School for International Health and Department of Health Systems Management, Ben Gurion University of the Negev, Israel; School of Public Health, University of Michigan, USA. Electronic address: katzmar@post.bgu.ac.il.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Knight, Marian" sort="Knight, Marian" uniqKey="Knight M" first="Marian" last="Knight">Marian Knight</name>
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<nlm:affiliation>National Perinatal Epidemiology Unit, University of Oxford, UK. Electronic address: marian.knight@npeu.ox.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lee, Vernon J" sort="Lee, Vernon J" uniqKey="Lee V" first="Vernon J" last="Lee">Vernon J. Lee</name>
<affiliation>
<nlm:affiliation>Saw Swee Hock School of Public Health, National University of Singapore, Singapore. Electronic address: vernonljm@hotmail.com.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Loeb, Mark" sort="Loeb, Mark" uniqKey="Loeb M" first="Mark" last="Loeb">Mark Loeb</name>
<affiliation>
<nlm:affiliation>Institute for Infectious Disease Research, McMaster University, Canada. Electronic address: loebm@mcmaster.ca.</nlm:affiliation>
</affiliation>
</author>
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<name sortKey="Luteijn, Johannes M" sort="Luteijn, Johannes M" uniqKey="Luteijn J" first="Johannes M" last="Luteijn">Johannes M. Luteijn</name>
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<nlm:affiliation>Queen Mary, University of London, UK. Electronic address: j.m.luteijn@qmul.ac.uk.</nlm:affiliation>
</affiliation>
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<author>
<name sortKey="Marshall, Helen" sort="Marshall, Helen" uniqKey="Marshall H" first="Helen" last="Marshall">Helen Marshall</name>
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<nlm:affiliation>Robinson Research Institute and Adelaide Medical School, University of Adelaide and Women's and Children's Health Network, Australia. Electronic address: helen.marshall@adelaide.edu.au.</nlm:affiliation>
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<name sortKey="Nair, Harish" sort="Nair, Harish" uniqKey="Nair H" first="Harish" last="Nair">Harish Nair</name>
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<nlm:affiliation>Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, UK. Electronic address: harish.nair@ed.ac.uk.</nlm:affiliation>
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</author>
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<name sortKey="Pottie, Kevin" sort="Pottie, Kevin" uniqKey="Pottie K" first="Kevin" last="Pottie">Kevin Pottie</name>
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<nlm:affiliation>Department of Family Medicine, University of Ottawa, Canada. Electronic address: kpottie@uottawa.ca.</nlm:affiliation>
</affiliation>
</author>
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<name sortKey="Salam, Rehana A" sort="Salam, Rehana A" uniqKey="Salam R" first="Rehana A" last="Salam">Rehana A. Salam</name>
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<nlm:affiliation>South Australian Health and Medical Research Institute, University of Adelaide, Australia; Division of Women and Child Health, Aga Khan University, Pakistan. Electronic address: rehana.salam@aku.edu.</nlm:affiliation>
</affiliation>
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<name sortKey="Savitz, David A" sort="Savitz, David A" uniqKey="Savitz D" first="David A" last="Savitz">David A. Savitz</name>
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<nlm:affiliation>Departments of Epidemiology and Obstetrics and Gynecology, Brown University, USA. Electronic address: david_savitz@brown.edu.</nlm:affiliation>
</affiliation>
</author>
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<name sortKey="Serruya, Suzanne J" sort="Serruya, Suzanne J" uniqKey="Serruya S" first="Suzanne J" last="Serruya">Suzanne J. Serruya</name>
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<nlm:affiliation>Latin American Center for Perinatology, Women and Reproductive Health, Panamerican Health Organization, Uruguay. Electronic address: serruyas@paho.org.</nlm:affiliation>
</affiliation>
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<name sortKey="Skidmore, Becky" sort="Skidmore, Becky" uniqKey="Skidmore B" first="Becky" last="Skidmore">Becky Skidmore</name>
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<nlm:affiliation>Independent Information Specialist, Canada. Electronic address: bskidmore@rogers.com.</nlm:affiliation>
</affiliation>
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<name sortKey="Ortiz, Justin R" sort="Ortiz, Justin R" uniqKey="Ortiz J" first="Justin R" last="Ortiz">Justin R. Ortiz</name>
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<nlm:affiliation>Initiative for Vaccine Research, World Health Organization, Switzerland. Electronic address: ortizj@who.int.</nlm:affiliation>
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<div type="abstract" xml:lang="en">From 2014 to 2017, the World Health Organization convened a working group to evaluate influenza disease burden and vaccine efficacy to inform estimates of maternal influenza immunization program impact. The group evaluated existing systematic reviews and relevant primary studies, and conducted four new systematic reviews. There was strong evidence that maternal influenza immunization prevented influenza illness in pregnant women and their infants, although data on severe illness prevention were lacking. The limited number of studies reporting influenza incidence in pregnant women and infants under six months had highly variable estimates and underrepresented low- and middle-income countries. The evidence that maternal influenza immunization reduces the risk of adverse birth outcomes was conflicting, and many observational studies were subject to substantial bias. The lack of scientific clarity regarding disease burden or magnitude of vaccine efficacy against severe illness poses challenges for robust estimation of the potential impact of maternal influenza immunization programs.</div>
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<AbstractText>From 2014 to 2017, the World Health Organization convened a working group to evaluate influenza disease burden and vaccine efficacy to inform estimates of maternal influenza immunization program impact. The group evaluated existing systematic reviews and relevant primary studies, and conducted four new systematic reviews. There was strong evidence that maternal influenza immunization prevented influenza illness in pregnant women and their infants, although data on severe illness prevention were lacking. The limited number of studies reporting influenza incidence in pregnant women and infants under six months had highly variable estimates and underrepresented low- and middle-income countries. The evidence that maternal influenza immunization reduces the risk of adverse birth outcomes was conflicting, and many observational studies were subject to substantial bias. The lack of scientific clarity regarding disease burden or magnitude of vaccine efficacy against severe illness poses challenges for robust estimation of the potential impact of maternal influenza immunization programs.</AbstractText>
<CopyrightInformation>Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.</CopyrightInformation>
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