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Antimicrobial Resistance in Gram-Negative Rods Causing Bacteremia in Hematopoietic Stem Cell Transplant Recipients: Intercontinental Prospective Study of the Infectious Diseases Working Party of the European Bone Marrow Transplantation Group.

Identifieur interne : 000055 ( PubMed/Corpus ); précédent : 000054; suivant : 000056

Antimicrobial Resistance in Gram-Negative Rods Causing Bacteremia in Hematopoietic Stem Cell Transplant Recipients: Intercontinental Prospective Study of the Infectious Diseases Working Party of the European Bone Marrow Transplantation Group.

Auteurs : Diana Averbuch ; Gloria Tridello ; Jennifer Hoek ; Malgorzata Mikulska ; Hamdi Akan ; Lucrecia Yanez San Segundo ; Thomas Pabst ; Tülay Özçelik ; Galina Klyasova ; Irene Donnini ; Depei Wu ; Zafer Gülbas ; Tsila Zuckerman ; Aida Botelho De Sousa ; Yves Beguin ; Aliénor Xhaard ; Emmanuel Bachy ; Per Ljungman ; Rafael De La Camara ; Jelena Rascon ; Isabel Ruiz Camps ; Antonin Vitek ; Francesca Patriarca ; Laura Cudillo ; Radovan Vrhovac ; Peter J. Shaw ; Tom Wolfs ; Tracey O'Brien ; Batia Avni ; Gerda Silling ; Firas Al Sabty ; Stelios Graphakos ; Marja Sankelo ; Henrik Sengeloev ; Srinivas Pillai ; Susanne Matthes ; Frederiki Melanthiou ; Simona Iacobelli ; Jan Styczynski ; Dan Engelhard ; Simone Cesaro

Source :

RBID : pubmed:29020364

Abstract

This intercontinental study aimed to study gram-negative rod (GNR) resistance in hematopoietic stem cell transplantation (HSCT).

DOI: 10.1093/cid/cix646
PubMed: 29020364

Links to Exploration step

pubmed:29020364

Le document en format XML

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<name sortKey="Averbuch, Diana" sort="Averbuch, Diana" uniqKey="Averbuch D" first="Diana" last="Averbuch">Diana Averbuch</name>
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<nlm:affiliation>Hadassah University Hospital, Jerusalem, Israel.</nlm:affiliation>
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<name sortKey="Tridello, Gloria" sort="Tridello, Gloria" uniqKey="Tridello G" first="Gloria" last="Tridello">Gloria Tridello</name>
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<nlm:affiliation>Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.</nlm:affiliation>
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<name sortKey="Hoek, Jennifer" sort="Hoek, Jennifer" uniqKey="Hoek J" first="Jennifer" last="Hoek">Jennifer Hoek</name>
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<nlm:affiliation>European Bone Marrow Transplantation Data Office, Leiden, The Netherlands.</nlm:affiliation>
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<name sortKey="Mikulska, Malgorzata" sort="Mikulska, Malgorzata" uniqKey="Mikulska M" first="Malgorzata" last="Mikulska">Malgorzata Mikulska</name>
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<nlm:affiliation>Ospedale San Martino, Genova, Italy.</nlm:affiliation>
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<name sortKey="Akan, Hamdi" sort="Akan, Hamdi" uniqKey="Akan H" first="Hamdi" last="Akan">Hamdi Akan</name>
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<nlm:affiliation>Faculty of Medicine, Ankara University, Turkey.</nlm:affiliation>
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<name sortKey="Yanez San Segundo, Lucrecia" sort="Yanez San Segundo, Lucrecia" uniqKey="Yanez San Segundo L" first="Lucrecia" last="Yanez San Segundo">Lucrecia Yanez San Segundo</name>
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<nlm:affiliation>Hospital Universitario Marqués de Valdecilla, Santander, Spain.</nlm:affiliation>
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<name sortKey="Pabst, Thomas" sort="Pabst, Thomas" uniqKey="Pabst T" first="Thomas" last="Pabst">Thomas Pabst</name>
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<nlm:affiliation>University Hospital, Bern, Switzerland.</nlm:affiliation>
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<author>
<name sortKey="Ozcelik, Tulay" sort="Ozcelik, Tulay" uniqKey="Ozcelik T" first="Tülay" last="Özçelik">Tülay Özçelik</name>
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<nlm:affiliation>Florence Nightingale Sisli Hospital, Istanbul, Turkey.</nlm:affiliation>
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<name sortKey="Klyasova, Galina" sort="Klyasova, Galina" uniqKey="Klyasova G" first="Galina" last="Klyasova">Galina Klyasova</name>
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<nlm:affiliation>National Research Center for Hematology, Moscow, Russia.</nlm:affiliation>
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<name sortKey="Donnini, Irene" sort="Donnini, Irene" uniqKey="Donnini I" first="Irene" last="Donnini">Irene Donnini</name>
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<nlm:affiliation>Azienda Ospedaliera Universitaria Careggi, Firenze, Italy.</nlm:affiliation>
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<author>
<name sortKey="Wu, Depei" sort="Wu, Depei" uniqKey="Wu D" first="Depei" last="Wu">Depei Wu</name>
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<nlm:affiliation>First Affiliated Hospital of Soochow University, Suzhou Jiangsu, China.</nlm:affiliation>
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<name sortKey="Gulbas, Zafer" sort="Gulbas, Zafer" uniqKey="Gulbas Z" first="Zafer" last="Gülbas">Zafer Gülbas</name>
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<nlm:affiliation>Anadolu Medical Center Hospital, Kocaeli, Turkey.</nlm:affiliation>
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<name sortKey="Zuckerman, Tsila" sort="Zuckerman, Tsila" uniqKey="Zuckerman T" first="Tsila" last="Zuckerman">Tsila Zuckerman</name>
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<nlm:affiliation>Rambam Medical Center, Haifa, Israel.</nlm:affiliation>
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<author>
<name sortKey="Botelho De Sousa, Aida" sort="Botelho De Sousa, Aida" uniqKey="Botelho De Sousa A" first="Aida" last="Botelho De Sousa">Aida Botelho De Sousa</name>
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<nlm:affiliation>Hospital dos Capuchos, Lisbon, Portugal.</nlm:affiliation>
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<author>
<name sortKey="Beguin, Yves" sort="Beguin, Yves" uniqKey="Beguin Y" first="Yves" last="Beguin">Yves Beguin</name>
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<nlm:affiliation>University of Liege, Belgium.</nlm:affiliation>
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<author>
<name sortKey="Xhaard, Alienor" sort="Xhaard, Alienor" uniqKey="Xhaard A" first="Aliénor" last="Xhaard">Aliénor Xhaard</name>
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<nlm:affiliation>Hospital St Louis, Paris, France.</nlm:affiliation>
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<name sortKey="Bachy, Emmanuel" sort="Bachy, Emmanuel" uniqKey="Bachy E" first="Emmanuel" last="Bachy">Emmanuel Bachy</name>
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<nlm:affiliation>Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, France.</nlm:affiliation>
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<name sortKey="Ljungman, Per" sort="Ljungman, Per" uniqKey="Ljungman P" first="Per" last="Ljungman">Per Ljungman</name>
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<nlm:affiliation>Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden.</nlm:affiliation>
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<name sortKey="De La Camara, Rafael" sort="De La Camara, Rafael" uniqKey="De La Camara R" first="Rafael" last="De La Camara">Rafael De La Camara</name>
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<nlm:affiliation>Hospital de la Princesa, Madrid, Spain.</nlm:affiliation>
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<name sortKey="Rascon, Jelena" sort="Rascon, Jelena" uniqKey="Rascon J" first="Jelena" last="Rascon">Jelena Rascon</name>
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<nlm:affiliation>University Hospital Santariskiu Klinikos, Vilnius, Lithuania.</nlm:affiliation>
</affiliation>
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<name sortKey="Ruiz Camps, Isabel" sort="Ruiz Camps, Isabel" uniqKey="Ruiz Camps I" first="Isabel" last="Ruiz Camps">Isabel Ruiz Camps</name>
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<nlm:affiliation>Hospital Vall d'Hebron, Barcelona, Spain.</nlm:affiliation>
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<author>
<name sortKey="Vitek, Antonin" sort="Vitek, Antonin" uniqKey="Vitek A" first="Antonin" last="Vitek">Antonin Vitek</name>
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<nlm:affiliation>Institute of Hematology and Blood Transfusion, Prague, Czech Republic.</nlm:affiliation>
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<name sortKey="Patriarca, Francesca" sort="Patriarca, Francesca" uniqKey="Patriarca F" first="Francesca" last="Patriarca">Francesca Patriarca</name>
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<nlm:affiliation>Azienda Ospedaliero Universitaria, Udine, Italy.</nlm:affiliation>
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<name sortKey="Cudillo, Laura" sort="Cudillo, Laura" uniqKey="Cudillo L" first="Laura" last="Cudillo">Laura Cudillo</name>
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<nlm:affiliation>Tor Vergata University, Rome, Italy.</nlm:affiliation>
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<name sortKey="Vrhovac, Radovan" sort="Vrhovac, Radovan" uniqKey="Vrhovac R" first="Radovan" last="Vrhovac">Radovan Vrhovac</name>
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<nlm:affiliation>University Hospital Center Rebro, Zagreb, Croatia.</nlm:affiliation>
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<name sortKey="Shaw, Peter J" sort="Shaw, Peter J" uniqKey="Shaw P" first="Peter J" last="Shaw">Peter J. Shaw</name>
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<nlm:affiliation>The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation>
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<name sortKey="Wolfs, Tom" sort="Wolfs, Tom" uniqKey="Wolfs T" first="Tom" last="Wolfs">Tom Wolfs</name>
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<nlm:affiliation>University Hospital for Children, Utrecht, The Netherlands.</nlm:affiliation>
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<name sortKey="O Brien, Tracey" sort="O Brien, Tracey" uniqKey="O Brien T" first="Tracey" last="O'Brien">Tracey O'Brien</name>
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<nlm:affiliation>Sydney Children's Hospital, Randwick, Australia.</nlm:affiliation>
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<name sortKey="Avni, Batia" sort="Avni, Batia" uniqKey="Avni B" first="Batia" last="Avni">Batia Avni</name>
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<nlm:affiliation>Hadassah University Hospital, Jerusalem, Israel.</nlm:affiliation>
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<name sortKey="Silling, Gerda" sort="Silling, Gerda" uniqKey="Silling G" first="Gerda" last="Silling">Gerda Silling</name>
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<nlm:affiliation>University of Münster, Germany.</nlm:affiliation>
</affiliation>
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<author>
<name sortKey="Al Sabty, Firas" sort="Al Sabty, Firas" uniqKey="Al Sabty F" first="Firas" last="Al Sabty">Firas Al Sabty</name>
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<nlm:affiliation>University Hospital, Bratislava, Slovakia.</nlm:affiliation>
</affiliation>
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<name sortKey="Graphakos, Stelios" sort="Graphakos, Stelios" uniqKey="Graphakos S" first="Stelios" last="Graphakos">Stelios Graphakos</name>
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<nlm:affiliation>St Sophia Children's Hospital, Athens, Greece.</nlm:affiliation>
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<name sortKey="Sankelo, Marja" sort="Sankelo, Marja" uniqKey="Sankelo M" first="Marja" last="Sankelo">Marja Sankelo</name>
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<nlm:affiliation>Tampere University Hospital, Finland.</nlm:affiliation>
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<name sortKey="Sengeloev, Henrik" sort="Sengeloev, Henrik" uniqKey="Sengeloev H" first="Henrik" last="Sengeloev">Henrik Sengeloev</name>
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<nlm:affiliation>Rigshospitalet, Copenhagen, Denmark.</nlm:affiliation>
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<name sortKey="Pillai, Srinivas" sort="Pillai, Srinivas" uniqKey="Pillai S" first="Srinivas" last="Pillai">Srinivas Pillai</name>
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<nlm:affiliation>University Hospital of North Staffordshire, Stoke, United Kingdom.</nlm:affiliation>
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<name sortKey="Matthes, Susanne" sort="Matthes, Susanne" uniqKey="Matthes S" first="Susanne" last="Matthes">Susanne Matthes</name>
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<nlm:affiliation>St Anna Kinderspital, Vienna, Austria.</nlm:affiliation>
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<name sortKey="Melanthiou, Frederiki" sort="Melanthiou, Frederiki" uniqKey="Melanthiou F" first="Frederiki" last="Melanthiou">Frederiki Melanthiou</name>
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<nlm:affiliation>Nicosia General Hospital, Nicosia Strovolos, Cyprus.</nlm:affiliation>
</affiliation>
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<name sortKey="Iacobelli, Simona" sort="Iacobelli, Simona" uniqKey="Iacobelli S" first="Simona" last="Iacobelli">Simona Iacobelli</name>
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<nlm:affiliation>Tor Vergata University, Rome, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Styczynski, Jan" sort="Styczynski, Jan" uniqKey="Styczynski J" first="Jan" last="Styczynski">Jan Styczynski</name>
<affiliation>
<nlm:affiliation>Collegium Medicum, Nicolaus Copernicus University Torun, Bydgoszcz, Poland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Engelhard, Dan" sort="Engelhard, Dan" uniqKey="Engelhard D" first="Dan" last="Engelhard">Dan Engelhard</name>
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<nlm:affiliation>Hadassah University Hospital, Jerusalem, Israel.</nlm:affiliation>
</affiliation>
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<name sortKey="Cesaro, Simone" sort="Cesaro, Simone" uniqKey="Cesaro S" first="Simone" last="Cesaro">Simone Cesaro</name>
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<nlm:affiliation>Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.</nlm:affiliation>
</affiliation>
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<title xml:lang="en">Antimicrobial Resistance in Gram-Negative Rods Causing Bacteremia in Hematopoietic Stem Cell Transplant Recipients: Intercontinental Prospective Study of the Infectious Diseases Working Party of the European Bone Marrow Transplantation Group.</title>
<author>
<name sortKey="Averbuch, Diana" sort="Averbuch, Diana" uniqKey="Averbuch D" first="Diana" last="Averbuch">Diana Averbuch</name>
<affiliation>
<nlm:affiliation>Hadassah University Hospital, Jerusalem, Israel.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tridello, Gloria" sort="Tridello, Gloria" uniqKey="Tridello G" first="Gloria" last="Tridello">Gloria Tridello</name>
<affiliation>
<nlm:affiliation>Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hoek, Jennifer" sort="Hoek, Jennifer" uniqKey="Hoek J" first="Jennifer" last="Hoek">Jennifer Hoek</name>
<affiliation>
<nlm:affiliation>European Bone Marrow Transplantation Data Office, Leiden, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mikulska, Malgorzata" sort="Mikulska, Malgorzata" uniqKey="Mikulska M" first="Malgorzata" last="Mikulska">Malgorzata Mikulska</name>
<affiliation>
<nlm:affiliation>Ospedale San Martino, Genova, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Akan, Hamdi" sort="Akan, Hamdi" uniqKey="Akan H" first="Hamdi" last="Akan">Hamdi Akan</name>
<affiliation>
<nlm:affiliation>Faculty of Medicine, Ankara University, Turkey.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Yanez San Segundo, Lucrecia" sort="Yanez San Segundo, Lucrecia" uniqKey="Yanez San Segundo L" first="Lucrecia" last="Yanez San Segundo">Lucrecia Yanez San Segundo</name>
<affiliation>
<nlm:affiliation>Hospital Universitario Marqués de Valdecilla, Santander, Spain.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pabst, Thomas" sort="Pabst, Thomas" uniqKey="Pabst T" first="Thomas" last="Pabst">Thomas Pabst</name>
<affiliation>
<nlm:affiliation>University Hospital, Bern, Switzerland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ozcelik, Tulay" sort="Ozcelik, Tulay" uniqKey="Ozcelik T" first="Tülay" last="Özçelik">Tülay Özçelik</name>
<affiliation>
<nlm:affiliation>Florence Nightingale Sisli Hospital, Istanbul, Turkey.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Klyasova, Galina" sort="Klyasova, Galina" uniqKey="Klyasova G" first="Galina" last="Klyasova">Galina Klyasova</name>
<affiliation>
<nlm:affiliation>National Research Center for Hematology, Moscow, Russia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Donnini, Irene" sort="Donnini, Irene" uniqKey="Donnini I" first="Irene" last="Donnini">Irene Donnini</name>
<affiliation>
<nlm:affiliation>Azienda Ospedaliera Universitaria Careggi, Firenze, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wu, Depei" sort="Wu, Depei" uniqKey="Wu D" first="Depei" last="Wu">Depei Wu</name>
<affiliation>
<nlm:affiliation>First Affiliated Hospital of Soochow University, Suzhou Jiangsu, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gulbas, Zafer" sort="Gulbas, Zafer" uniqKey="Gulbas Z" first="Zafer" last="Gülbas">Zafer Gülbas</name>
<affiliation>
<nlm:affiliation>Anadolu Medical Center Hospital, Kocaeli, Turkey.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zuckerman, Tsila" sort="Zuckerman, Tsila" uniqKey="Zuckerman T" first="Tsila" last="Zuckerman">Tsila Zuckerman</name>
<affiliation>
<nlm:affiliation>Rambam Medical Center, Haifa, Israel.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Botelho De Sousa, Aida" sort="Botelho De Sousa, Aida" uniqKey="Botelho De Sousa A" first="Aida" last="Botelho De Sousa">Aida Botelho De Sousa</name>
<affiliation>
<nlm:affiliation>Hospital dos Capuchos, Lisbon, Portugal.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Beguin, Yves" sort="Beguin, Yves" uniqKey="Beguin Y" first="Yves" last="Beguin">Yves Beguin</name>
<affiliation>
<nlm:affiliation>University of Liege, Belgium.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Xhaard, Alienor" sort="Xhaard, Alienor" uniqKey="Xhaard A" first="Aliénor" last="Xhaard">Aliénor Xhaard</name>
<affiliation>
<nlm:affiliation>Hospital St Louis, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bachy, Emmanuel" sort="Bachy, Emmanuel" uniqKey="Bachy E" first="Emmanuel" last="Bachy">Emmanuel Bachy</name>
<affiliation>
<nlm:affiliation>Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ljungman, Per" sort="Ljungman, Per" uniqKey="Ljungman P" first="Per" last="Ljungman">Per Ljungman</name>
<affiliation>
<nlm:affiliation>Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="De La Camara, Rafael" sort="De La Camara, Rafael" uniqKey="De La Camara R" first="Rafael" last="De La Camara">Rafael De La Camara</name>
<affiliation>
<nlm:affiliation>Hospital de la Princesa, Madrid, Spain.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Rascon, Jelena" sort="Rascon, Jelena" uniqKey="Rascon J" first="Jelena" last="Rascon">Jelena Rascon</name>
<affiliation>
<nlm:affiliation>University Hospital Santariskiu Klinikos, Vilnius, Lithuania.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ruiz Camps, Isabel" sort="Ruiz Camps, Isabel" uniqKey="Ruiz Camps I" first="Isabel" last="Ruiz Camps">Isabel Ruiz Camps</name>
<affiliation>
<nlm:affiliation>Hospital Vall d'Hebron, Barcelona, Spain.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vitek, Antonin" sort="Vitek, Antonin" uniqKey="Vitek A" first="Antonin" last="Vitek">Antonin Vitek</name>
<affiliation>
<nlm:affiliation>Institute of Hematology and Blood Transfusion, Prague, Czech Republic.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Patriarca, Francesca" sort="Patriarca, Francesca" uniqKey="Patriarca F" first="Francesca" last="Patriarca">Francesca Patriarca</name>
<affiliation>
<nlm:affiliation>Azienda Ospedaliero Universitaria, Udine, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cudillo, Laura" sort="Cudillo, Laura" uniqKey="Cudillo L" first="Laura" last="Cudillo">Laura Cudillo</name>
<affiliation>
<nlm:affiliation>Tor Vergata University, Rome, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vrhovac, Radovan" sort="Vrhovac, Radovan" uniqKey="Vrhovac R" first="Radovan" last="Vrhovac">Radovan Vrhovac</name>
<affiliation>
<nlm:affiliation>University Hospital Center Rebro, Zagreb, Croatia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Shaw, Peter J" sort="Shaw, Peter J" uniqKey="Shaw P" first="Peter J" last="Shaw">Peter J. Shaw</name>
<affiliation>
<nlm:affiliation>The Children's Hospital at Westmead, Sydney, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wolfs, Tom" sort="Wolfs, Tom" uniqKey="Wolfs T" first="Tom" last="Wolfs">Tom Wolfs</name>
<affiliation>
<nlm:affiliation>University Hospital for Children, Utrecht, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="O Brien, Tracey" sort="O Brien, Tracey" uniqKey="O Brien T" first="Tracey" last="O'Brien">Tracey O'Brien</name>
<affiliation>
<nlm:affiliation>Sydney Children's Hospital, Randwick, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Avni, Batia" sort="Avni, Batia" uniqKey="Avni B" first="Batia" last="Avni">Batia Avni</name>
<affiliation>
<nlm:affiliation>Hadassah University Hospital, Jerusalem, Israel.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Silling, Gerda" sort="Silling, Gerda" uniqKey="Silling G" first="Gerda" last="Silling">Gerda Silling</name>
<affiliation>
<nlm:affiliation>University of Münster, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Al Sabty, Firas" sort="Al Sabty, Firas" uniqKey="Al Sabty F" first="Firas" last="Al Sabty">Firas Al Sabty</name>
<affiliation>
<nlm:affiliation>University Hospital, Bratislava, Slovakia.</nlm:affiliation>
</affiliation>
</author>
<author>
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<nlm:affiliation>St Sophia Children's Hospital, Athens, Greece.</nlm:affiliation>
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</author>
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<name sortKey="Sankelo, Marja" sort="Sankelo, Marja" uniqKey="Sankelo M" first="Marja" last="Sankelo">Marja Sankelo</name>
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<nlm:affiliation>Tampere University Hospital, Finland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Sengeloev, Henrik" sort="Sengeloev, Henrik" uniqKey="Sengeloev H" first="Henrik" last="Sengeloev">Henrik Sengeloev</name>
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</affiliation>
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<nlm:affiliation>University Hospital of North Staffordshire, Stoke, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
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<name sortKey="Matthes, Susanne" sort="Matthes, Susanne" uniqKey="Matthes S" first="Susanne" last="Matthes">Susanne Matthes</name>
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</affiliation>
</author>
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<name sortKey="Melanthiou, Frederiki" sort="Melanthiou, Frederiki" uniqKey="Melanthiou F" first="Frederiki" last="Melanthiou">Frederiki Melanthiou</name>
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<nlm:affiliation>Nicosia General Hospital, Nicosia Strovolos, Cyprus.</nlm:affiliation>
</affiliation>
</author>
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<nlm:affiliation>Tor Vergata University, Rome, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Styczynski, Jan" sort="Styczynski, Jan" uniqKey="Styczynski J" first="Jan" last="Styczynski">Jan Styczynski</name>
<affiliation>
<nlm:affiliation>Collegium Medicum, Nicolaus Copernicus University Torun, Bydgoszcz, Poland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Engelhard, Dan" sort="Engelhard, Dan" uniqKey="Engelhard D" first="Dan" last="Engelhard">Dan Engelhard</name>
<affiliation>
<nlm:affiliation>Hadassah University Hospital, Jerusalem, Israel.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cesaro, Simone" sort="Cesaro, Simone" uniqKey="Cesaro S" first="Simone" last="Cesaro">Simone Cesaro</name>
<affiliation>
<nlm:affiliation>Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.</nlm:affiliation>
</affiliation>
</author>
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<series>
<title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title>
<idno type="eISSN">1537-6591</idno>
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<date when="2017" type="published">2017</date>
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<front>
<div type="abstract" xml:lang="en">This intercontinental study aimed to study gram-negative rod (GNR) resistance in hematopoietic stem cell transplantation (HSCT).</div>
</front>
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<DateCreated>
<Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
</DateCreated>
<DateRevised>
<Year>2017</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
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<Journal>
<ISSN IssnType="Electronic">1537-6591</ISSN>
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<Volume>65</Volume>
<Issue>11</Issue>
<PubDate>
<Year>2017</Year>
<Month>Nov</Month>
<Day>13</Day>
</PubDate>
</JournalIssue>
<Title>Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</Title>
<ISOAbbreviation>Clin. Infect. Dis.</ISOAbbreviation>
</Journal>
<ArticleTitle>Antimicrobial Resistance in Gram-Negative Rods Causing Bacteremia in Hematopoietic Stem Cell Transplant Recipients: Intercontinental Prospective Study of the Infectious Diseases Working Party of the European Bone Marrow Transplantation Group.</ArticleTitle>
<Pagination>
<MedlinePgn>1819-1828</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1093/cid/cix646</ELocationID>
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<AbstractText Label="Background" NlmCategory="UNASSIGNED">This intercontinental study aimed to study gram-negative rod (GNR) resistance in hematopoietic stem cell transplantation (HSCT).</AbstractText>
<AbstractText Label="Methods" NlmCategory="UNASSIGNED">GNR bacteremias occurring during 6 months post-HSCT (February 2014-May 2015) were prospectively collected, and analyzed for rates and risk factors for resistance to fluoroquinolones, noncarbapenem anti-Pseudomonas β-lactams (noncarbapenems), carbapenems, and multidrug resistance.</AbstractText>
<AbstractText Label="Results" NlmCategory="UNASSIGNED">Sixty-five HSCT centers from 25 countries in Europe, Australia, and Asia reported data on 655 GNR episodes and 704 pathogens in 591 patients (Enterobacteriaceae, 73%; nonfermentative rods, 24%; and 3% others). Half of GNRs were fluoroquinolone and noncarbapenem resistant; 18.5% carbapenem resistant; 35.2% multidrug resistant. The total resistance rates were higher in allogeneic HSCT (allo-HSCT) vs autologous HSCT (auto-HSCT) patients (P < .001) but similar in community-acquired infections. Noncarbapenem resistance and multidrug resistance were higher in auto-HSCT patients in centers providing vs not providing fluoroquinolone prophylaxis (P < .01). Resistance rates were higher in southeast vs northwest Europe and similar in children and adults, excluding higher fluoroquinolone- and β-lactam/β-lactamase inhibitor resistance rates in allo-HSCT adults. Non-Klebsiella Enterobacteriaceae were rarely carbapenem resistant. Multivariable analysis revealed resistance risk factors in allo-HSCT patients: fluoroquinolone resistance: adult, prolonged neutropenia, breakthrough on fluoroquinolones; noncarbapenem resistance: hospital-acquired infection, breakthrough on noncarbapenems or other antibiotics (excluding fluoroquinolones, noncarbapenems, carbapenems), donor type; carbapenem resistance: breakthrough on carbapenem, longer hospitalization, intensive care unit, previous other antibiotic therapy; multidrug resistance: longer hospitalization, breakthrough on β-lactam/β-lactamase inhibitors, and carbapenems. Inappropriate empiric therapy and mortality were significantly more common in infections caused by resistant bacteria.</AbstractText>
<AbstractText Label="Conclusions" NlmCategory="UNASSIGNED">Our data question the recommendation for fluoroquinolone prophylaxis and call for reassessment of local empiric antibiotic protocols. Knowledge of pathogen-specific resistance enables early appropriate empiric therapy. Monitoring of resistance is crucial.</AbstractText>
<AbstractText Label="Clinical Trials Registration" NlmCategory="UNASSIGNED">NCT02257931.</AbstractText>
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<LastName>Averbuch</LastName>
<ForeName>Diana</ForeName>
<Initials>D</Initials>
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<Affiliation>Hadassah University Hospital, Jerusalem, Israel.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>Gloria</ForeName>
<Initials>G</Initials>
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<Affiliation>Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Hoek</LastName>
<ForeName>Jennifer</ForeName>
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</AffiliationInfo>
</Author>
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<LastName>Mikulska</LastName>
<ForeName>Malgorzata</ForeName>
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