Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial.
Identifieur interne : 000004 ( PubMed/Corpus ); précédent : 000003; suivant : 000005Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial.
Auteurs : Miguel Martin ; Frankie A. Holmes ; Bent Ejlertsen ; Suzette Delaloge ; Beverly Moy ; Hiroji Iwata ; Gunter Von Minckwitz ; Stephen K L. Chia ; Janine Mansi ; Carlos H. Barrios ; Michael Gnant ; Zorica Tomaševi ; Neelima Denduluri ; Robert Šeparovi ; Erhan Gokmen ; Anna Bashford ; Manuel Ruiz Borrego ; Sung-Bae Kim ; Erik Hugger Jakobsen ; Audrone Ciceniene ; Kenichi Inoue ; Friedrich Overkamp ; Joan B. Heijns ; Anne C. Armstrong ; John S. Link ; Anil Abraham Joy ; Richard Bryce ; Alvin Wong ; Susan Moran ; Bin Yao ; Feng Xu ; Alan Auerbach ; Marc Buyse ; Arlene ChanSource :
- The Lancet. Oncology [ 1474-5488 ] ; 2017.
Abstract
ExteNET showed that 1 year of neratinib, an irreversible pan-HER tyrosine kinase inhibitor, significantly improves 2-year invasive disease-free survival after trastuzumab-based adjuvant therapy in women with HER2-positive breast cancer. We report updated efficacy outcomes from a protocol-defined 5-year follow-up sensitivity analysis and long-term toxicity findings.
DOI: 10.1016/S1470-2045(17)30717-9
PubMed: 29146401
Links to Exploration step
pubmed:29146401Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial.</title><author><name sortKey="Martin, Miguel" sort="Martin, Miguel" uniqKey="Martin M" first="Miguel" last="Martin">Miguel Martin</name><affiliation><nlm:affiliation>Instituto de Investigación Sanitaria Gregorio Marañón, Grupo Español de Investigación en Cáncer de Mama (GEICAM), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Universidad Complutense, Madrid, Spain. Electronic address: mmartin@geicam.org.</nlm:affiliation></affiliation></author><author><name sortKey="Holmes, Frankie A" sort="Holmes, Frankie A" uniqKey="Holmes F" first="Frankie A" last="Holmes">Frankie A. Holmes</name><affiliation><nlm:affiliation>Texas Oncology, Houston, TX, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><affiliation><nlm:affiliation>Rigshospitalet, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Delaloge, Suzette" sort="Delaloge, Suzette" uniqKey="Delaloge S" first="Suzette" last="Delaloge">Suzette Delaloge</name><affiliation><nlm:affiliation>Institut Gustave Roussy, Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Moy, Beverly" sort="Moy, Beverly" uniqKey="Moy B" first="Beverly" last="Moy">Beverly Moy</name><affiliation><nlm:affiliation>Massachusetts General Hospital Cancer Center, Boston, MA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Iwata, Hiroji" sort="Iwata, Hiroji" uniqKey="Iwata H" first="Hiroji" last="Iwata">Hiroji Iwata</name><affiliation><nlm:affiliation>Aichi Cancer Center, Chikusa-ku, Nagoya, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Von Minckwitz, Gunter" sort="Von Minckwitz, Gunter" uniqKey="Von Minckwitz G" first="Gunter" last="Von Minckwitz">Gunter Von Minckwitz</name><affiliation><nlm:affiliation>Luisenkrankenhaus, German Breast Group Forschungs GmbH, Düsseldorf, Neulsenburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Chia, Stephen K L" sort="Chia, Stephen K L" uniqKey="Chia S" first="Stephen K L" last="Chia">Stephen K L. Chia</name><affiliation><nlm:affiliation>BC Cancer Agency, Vancouver, BC, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Mansi, Janine" sort="Mansi, Janine" uniqKey="Mansi J" first="Janine" last="Mansi">Janine Mansi</name><affiliation><nlm:affiliation>Guy's and St Thomas' Hospital National Health Service Foundation Trust and Biomedical Research Centre, King's College, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Barrios, Carlos H" sort="Barrios, Carlos H" uniqKey="Barrios C" first="Carlos H" last="Barrios">Carlos H. Barrios</name><affiliation><nlm:affiliation>Pontifical Catholic University of Rio Grande do Sul School of Medicine, Porto Alegre, Brazil.</nlm:affiliation></affiliation></author><author><name sortKey="Gnant, Michael" sort="Gnant, Michael" uniqKey="Gnant M" first="Michael" last="Gnant">Michael Gnant</name><affiliation><nlm:affiliation>Department of Surgery and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Tomasevi, Zorica" sort="Tomasevi, Zorica" uniqKey="Tomasevi Z" first="Zorica" last="Tomaševi">Zorica Tomaševi</name><affiliation><nlm:affiliation>Daily Chemotherapy Hospital, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.</nlm:affiliation></affiliation></author><author><name sortKey="Denduluri, Neelima" sort="Denduluri, Neelima" uniqKey="Denduluri N" first="Neelima" last="Denduluri">Neelima Denduluri</name><affiliation><nlm:affiliation>Virginia Cancer Specialists, Arlington, VA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Separovi, Robert" sort="Separovi, Robert" uniqKey="Separovi R" first="Robert" last="Šeparovi">Robert Šeparovi</name><affiliation><nlm:affiliation>University Hospital for Tumors, University Hospital Center "Sestre milosrdnice", Zagreb, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Gokmen, Erhan" sort="Gokmen, Erhan" uniqKey="Gokmen E" first="Erhan" last="Gokmen">Erhan Gokmen</name><affiliation><nlm:affiliation>Ege University Faculty of Medicine, Izmir, Turkey.</nlm:affiliation></affiliation></author><author><name sortKey="Bashford, Anna" sort="Bashford, Anna" uniqKey="Bashford A" first="Anna" last="Bashford">Anna Bashford</name><affiliation><nlm:affiliation>Auckland Hospital, Auckland, New Zealand.</nlm:affiliation></affiliation></author><author><name sortKey="Ruiz Borrego, Manuel" sort="Ruiz Borrego, Manuel" uniqKey="Ruiz Borrego M" first="Manuel" last="Ruiz Borrego">Manuel Ruiz Borrego</name><affiliation><nlm:affiliation>Oncology Department, Hospital Universitario Virgen del Rocio, Seville, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Sung Bae" sort="Kim, Sung Bae" uniqKey="Kim S" first="Sung-Bae" last="Kim">Sung-Bae Kim</name><affiliation><nlm:affiliation>Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Jakobsen, Erik Hugger" sort="Jakobsen, Erik Hugger" uniqKey="Jakobsen E" first="Erik Hugger" last="Jakobsen">Erik Hugger Jakobsen</name><affiliation><nlm:affiliation>Department of Oncology, Lillebaelt Hospital, Vejle, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Ciceniene, Audrone" sort="Ciceniene, Audrone" uniqKey="Ciceniene A" first="Audrone" last="Ciceniene">Audrone Ciceniene</name><affiliation><nlm:affiliation>Oncology Institute of Vilnius University, Vilnius, Lithuania.</nlm:affiliation></affiliation></author><author><name sortKey="Inoue, Kenichi" sort="Inoue, Kenichi" uniqKey="Inoue K" first="Kenichi" last="Inoue">Kenichi Inoue</name><affiliation><nlm:affiliation>Breast Oncology, Saitama Cancer Center, Kita-Adachi, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Overkamp, Friedrich" sort="Overkamp, Friedrich" uniqKey="Overkamp F" first="Friedrich" last="Overkamp">Friedrich Overkamp</name><affiliation><nlm:affiliation>Oncologianova GmbH, Recklinghausen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Heijns, Joan B" sort="Heijns, Joan B" uniqKey="Heijns J" first="Joan B" last="Heijns">Joan B. Heijns</name><affiliation><nlm:affiliation>Department of Medical Oncology, Amphia Hospital, Breda, Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Armstrong, Anne C" sort="Armstrong, Anne C" uniqKey="Armstrong A" first="Anne C" last="Armstrong">Anne C. Armstrong</name><affiliation><nlm:affiliation>Department of Oncology, Christie Hospital Manchester, Manchester, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Link, John S" sort="Link, John S" uniqKey="Link J" first="John S" last="Link">John S. Link</name><affiliation><nlm:affiliation>Breastlink Medical Group Inc, Santa Ana, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Joy, Anil Abraham" sort="Joy, Anil Abraham" uniqKey="Joy A" first="Anil Abraham" last="Joy">Anil Abraham Joy</name><affiliation><nlm:affiliation>University of Alberta, Department of Oncology, Cross Cancer Institute, Edmonton, AB, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Bryce, Richard" sort="Bryce, Richard" uniqKey="Bryce R" first="Richard" last="Bryce">Richard Bryce</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wong, Alvin" sort="Wong, Alvin" uniqKey="Wong A" first="Alvin" last="Wong">Alvin Wong</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Moran, Susan" sort="Moran, Susan" uniqKey="Moran S" first="Susan" last="Moran">Susan Moran</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Yao, Bin" sort="Yao, Bin" uniqKey="Yao B" first="Bin" last="Yao">Bin Yao</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Xu, Feng" sort="Xu, Feng" uniqKey="Xu F" first="Feng" last="Xu">Feng Xu</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Auerbach, Alan" sort="Auerbach, Alan" uniqKey="Auerbach A" first="Alan" last="Auerbach">Alan Auerbach</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Buyse, Marc" sort="Buyse, Marc" uniqKey="Buyse M" first="Marc" last="Buyse">Marc Buyse</name><affiliation><nlm:affiliation>International Drug Development Institute, Louvain-la-Neuve, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Chan, Arlene" sort="Chan, Arlene" uniqKey="Chan A" first="Arlene" last="Chan">Arlene Chan</name><affiliation><nlm:affiliation>Breast Cancer Research Centre-Western Australia, Perth, WA, Australia; Curtin University, Perth, WA, Australia.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:29146401</idno><idno type="pmid">29146401</idno><idno type="doi">10.1016/S1470-2045(17)30717-9</idno><idno type="wicri:Area/PubMed/Corpus">000004</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000004</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial.</title><author><name sortKey="Martin, Miguel" sort="Martin, Miguel" uniqKey="Martin M" first="Miguel" last="Martin">Miguel Martin</name><affiliation><nlm:affiliation>Instituto de Investigación Sanitaria Gregorio Marañón, Grupo Español de Investigación en Cáncer de Mama (GEICAM), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Universidad Complutense, Madrid, Spain. Electronic address: mmartin@geicam.org.</nlm:affiliation></affiliation></author><author><name sortKey="Holmes, Frankie A" sort="Holmes, Frankie A" uniqKey="Holmes F" first="Frankie A" last="Holmes">Frankie A. Holmes</name><affiliation><nlm:affiliation>Texas Oncology, Houston, TX, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><affiliation><nlm:affiliation>Rigshospitalet, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Delaloge, Suzette" sort="Delaloge, Suzette" uniqKey="Delaloge S" first="Suzette" last="Delaloge">Suzette Delaloge</name><affiliation><nlm:affiliation>Institut Gustave Roussy, Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Moy, Beverly" sort="Moy, Beverly" uniqKey="Moy B" first="Beverly" last="Moy">Beverly Moy</name><affiliation><nlm:affiliation>Massachusetts General Hospital Cancer Center, Boston, MA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Iwata, Hiroji" sort="Iwata, Hiroji" uniqKey="Iwata H" first="Hiroji" last="Iwata">Hiroji Iwata</name><affiliation><nlm:affiliation>Aichi Cancer Center, Chikusa-ku, Nagoya, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Von Minckwitz, Gunter" sort="Von Minckwitz, Gunter" uniqKey="Von Minckwitz G" first="Gunter" last="Von Minckwitz">Gunter Von Minckwitz</name><affiliation><nlm:affiliation>Luisenkrankenhaus, German Breast Group Forschungs GmbH, Düsseldorf, Neulsenburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Chia, Stephen K L" sort="Chia, Stephen K L" uniqKey="Chia S" first="Stephen K L" last="Chia">Stephen K L. Chia</name><affiliation><nlm:affiliation>BC Cancer Agency, Vancouver, BC, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Mansi, Janine" sort="Mansi, Janine" uniqKey="Mansi J" first="Janine" last="Mansi">Janine Mansi</name><affiliation><nlm:affiliation>Guy's and St Thomas' Hospital National Health Service Foundation Trust and Biomedical Research Centre, King's College, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Barrios, Carlos H" sort="Barrios, Carlos H" uniqKey="Barrios C" first="Carlos H" last="Barrios">Carlos H. Barrios</name><affiliation><nlm:affiliation>Pontifical Catholic University of Rio Grande do Sul School of Medicine, Porto Alegre, Brazil.</nlm:affiliation></affiliation></author><author><name sortKey="Gnant, Michael" sort="Gnant, Michael" uniqKey="Gnant M" first="Michael" last="Gnant">Michael Gnant</name><affiliation><nlm:affiliation>Department of Surgery and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Tomasevi, Zorica" sort="Tomasevi, Zorica" uniqKey="Tomasevi Z" first="Zorica" last="Tomaševi">Zorica Tomaševi</name><affiliation><nlm:affiliation>Daily Chemotherapy Hospital, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.</nlm:affiliation></affiliation></author><author><name sortKey="Denduluri, Neelima" sort="Denduluri, Neelima" uniqKey="Denduluri N" first="Neelima" last="Denduluri">Neelima Denduluri</name><affiliation><nlm:affiliation>Virginia Cancer Specialists, Arlington, VA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Separovi, Robert" sort="Separovi, Robert" uniqKey="Separovi R" first="Robert" last="Šeparovi">Robert Šeparovi</name><affiliation><nlm:affiliation>University Hospital for Tumors, University Hospital Center "Sestre milosrdnice", Zagreb, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Gokmen, Erhan" sort="Gokmen, Erhan" uniqKey="Gokmen E" first="Erhan" last="Gokmen">Erhan Gokmen</name><affiliation><nlm:affiliation>Ege University Faculty of Medicine, Izmir, Turkey.</nlm:affiliation></affiliation></author><author><name sortKey="Bashford, Anna" sort="Bashford, Anna" uniqKey="Bashford A" first="Anna" last="Bashford">Anna Bashford</name><affiliation><nlm:affiliation>Auckland Hospital, Auckland, New Zealand.</nlm:affiliation></affiliation></author><author><name sortKey="Ruiz Borrego, Manuel" sort="Ruiz Borrego, Manuel" uniqKey="Ruiz Borrego M" first="Manuel" last="Ruiz Borrego">Manuel Ruiz Borrego</name><affiliation><nlm:affiliation>Oncology Department, Hospital Universitario Virgen del Rocio, Seville, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Sung Bae" sort="Kim, Sung Bae" uniqKey="Kim S" first="Sung-Bae" last="Kim">Sung-Bae Kim</name><affiliation><nlm:affiliation>Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Jakobsen, Erik Hugger" sort="Jakobsen, Erik Hugger" uniqKey="Jakobsen E" first="Erik Hugger" last="Jakobsen">Erik Hugger Jakobsen</name><affiliation><nlm:affiliation>Department of Oncology, Lillebaelt Hospital, Vejle, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Ciceniene, Audrone" sort="Ciceniene, Audrone" uniqKey="Ciceniene A" first="Audrone" last="Ciceniene">Audrone Ciceniene</name><affiliation><nlm:affiliation>Oncology Institute of Vilnius University, Vilnius, Lithuania.</nlm:affiliation></affiliation></author><author><name sortKey="Inoue, Kenichi" sort="Inoue, Kenichi" uniqKey="Inoue K" first="Kenichi" last="Inoue">Kenichi Inoue</name><affiliation><nlm:affiliation>Breast Oncology, Saitama Cancer Center, Kita-Adachi, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Overkamp, Friedrich" sort="Overkamp, Friedrich" uniqKey="Overkamp F" first="Friedrich" last="Overkamp">Friedrich Overkamp</name><affiliation><nlm:affiliation>Oncologianova GmbH, Recklinghausen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Heijns, Joan B" sort="Heijns, Joan B" uniqKey="Heijns J" first="Joan B" last="Heijns">Joan B. Heijns</name><affiliation><nlm:affiliation>Department of Medical Oncology, Amphia Hospital, Breda, Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Armstrong, Anne C" sort="Armstrong, Anne C" uniqKey="Armstrong A" first="Anne C" last="Armstrong">Anne C. Armstrong</name><affiliation><nlm:affiliation>Department of Oncology, Christie Hospital Manchester, Manchester, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Link, John S" sort="Link, John S" uniqKey="Link J" first="John S" last="Link">John S. Link</name><affiliation><nlm:affiliation>Breastlink Medical Group Inc, Santa Ana, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Joy, Anil Abraham" sort="Joy, Anil Abraham" uniqKey="Joy A" first="Anil Abraham" last="Joy">Anil Abraham Joy</name><affiliation><nlm:affiliation>University of Alberta, Department of Oncology, Cross Cancer Institute, Edmonton, AB, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Bryce, Richard" sort="Bryce, Richard" uniqKey="Bryce R" first="Richard" last="Bryce">Richard Bryce</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wong, Alvin" sort="Wong, Alvin" uniqKey="Wong A" first="Alvin" last="Wong">Alvin Wong</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Moran, Susan" sort="Moran, Susan" uniqKey="Moran S" first="Susan" last="Moran">Susan Moran</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Yao, Bin" sort="Yao, Bin" uniqKey="Yao B" first="Bin" last="Yao">Bin Yao</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Xu, Feng" sort="Xu, Feng" uniqKey="Xu F" first="Feng" last="Xu">Feng Xu</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Auerbach, Alan" sort="Auerbach, Alan" uniqKey="Auerbach A" first="Alan" last="Auerbach">Alan Auerbach</name><affiliation><nlm:affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Buyse, Marc" sort="Buyse, Marc" uniqKey="Buyse M" first="Marc" last="Buyse">Marc Buyse</name><affiliation><nlm:affiliation>International Drug Development Institute, Louvain-la-Neuve, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Chan, Arlene" sort="Chan, Arlene" uniqKey="Chan A" first="Arlene" last="Chan">Arlene Chan</name><affiliation><nlm:affiliation>Breast Cancer Research Centre-Western Australia, Perth, WA, Australia; Curtin University, Perth, WA, Australia.</nlm:affiliation></affiliation></author></analytic><series><title level="j">The Lancet. Oncology</title><idno type="eISSN">1474-5488</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">ExteNET showed that 1 year of neratinib, an irreversible pan-HER tyrosine kinase inhibitor, significantly improves 2-year invasive disease-free survival after trastuzumab-based adjuvant therapy in women with HER2-positive breast cancer. We report updated efficacy outcomes from a protocol-defined 5-year follow-up sensitivity analysis and long-term toxicity findings.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">29146401</PMID><DateCreated><Year>2017</Year><Month>11</Month><Day>17</Day></DateCreated><DateRevised><Year>2017</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1474-5488</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2017</Year><Month>Nov</Month><Day>13</Day></PubDate></JournalIssue><Title>The Lancet. Oncology</Title><ISOAbbreviation>Lancet Oncol.</ISOAbbreviation></Journal><ArticleTitle>Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">S1470-2045(17)30717-9</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/S1470-2045(17)30717-9</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">ExteNET showed that 1 year of neratinib, an irreversible pan-HER tyrosine kinase inhibitor, significantly improves 2-year invasive disease-free survival after trastuzumab-based adjuvant therapy in women with HER2-positive breast cancer. We report updated efficacy outcomes from a protocol-defined 5-year follow-up sensitivity analysis and long-term toxicity findings.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">In this ongoing randomised, double-blind, placebo-controlled, phase 3 trial, eligible women aged 18 years or older (≥20 years in Japan) with stage 1-3c (modified to stage 2-3c in February, 2010) operable breast cancer, who had completed neoadjuvant and adjuvant chemotherapy plus trastuzumab with no evidence of disease recurrence or metastatic disease at study entry. Patients who were eligible patients were randomly assigned (1:1) via permuted blocks stratified according to hormone receptor status (hormone receptor-positive vs hormone receptor-negative), nodal status (0 vs 1-3 vs or ≥4 positive nodes), and trastuzumab adjuvant regimen (given sequentially vs concurrently with chemotherapy), then implemented centrally via an interactive voice and web-response system, to receive 1 year of oral neratinib 240 mg/day or matching placebo. Treatment was given continuously for 1 year, unless disease recurrence or new breast cancer, intolerable adverse events, or consent withdrawal occurred. Patients, investigators, and trial funder were masked to treatment allocation. The predefined endpoint of the 5-year analysis was invasive disease-free survival, analysed by intention to treat. ExteNET is registered with ClinicalTrials.gov, number NCT00878709, and is closed to new participants.</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">Between July 9, 2009, and Oct 24, 2011, 2840 eligible women with early HER2-positive breast cancer were recruited from community-based and academic institutions in 40 countries and randomly assigned to receive neratinib (n=1420) or placebo (n=1420). After a median follow-up of 5·2 years (IQR 2·1-5·3), patients in the neratinib group had significantly fewer invasive disease-free survival events than those in the placebo group (116 vs 163 events; stratified hazard ratio 0·73, 95% CI 0·57-0·92, p=0·0083). The 5-year invasive disease-free survival was 90·2% (95% CI 88·3-91·8) in the neratinib group and 87·7% (85·7-89·4) in the placebo group. Without diarrhoea prophylaxis, the most common grade 3-4 adverse events in the neratinib group, compared with the placebo group, were diarrhoea (561 [40%] grade 3 and one [<1%] grade 4 with neratinib vs 23 [2%] grade 3 with placebo), vomiting (grade 3: 47 [3%] vs five [<1%]), and nausea (grade 3: 26 [2%] vs two [<1%]). Treatment-emergent serious adverse events occurred in 103 (7%) women in the neratinib group and 85 (6%) women in the placebo group. No evidence of increased risk of long-term toxicity or long-term adverse consequences of neratinib-associated diarrhoea were identified with neratinib compared with placebo.</AbstractText><AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">At the 5-year follow-up, 1 year of extended adjuvant therapy with neratinib, administered after chemotherapy and trastuzumab, significantly reduced the proportion of clinically relevant breast cancer relapses-ie, those that might lead to death, such as distant and locoregional relapses outside the preserved breast-without increasing the risk of long-term toxicity. An analysis of overall survival is planned after 248 events.</AbstractText><AbstractText Label="FUNDING" NlmCategory="BACKGROUND">Wyeth, Pfizer, and Puma Biotechnology.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Martin</LastName><ForeName>Miguel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Instituto de Investigación Sanitaria Gregorio Marañón, Grupo Español de Investigación en Cáncer de Mama (GEICAM), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Universidad Complutense, Madrid, Spain. Electronic address: mmartin@geicam.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Holmes</LastName><ForeName>Frankie A</ForeName><Initials>FA</Initials><AffiliationInfo><Affiliation>Texas Oncology, Houston, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ejlertsen</LastName><ForeName>Bent</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Rigshospitalet, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Delaloge</LastName><ForeName>Suzette</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institut Gustave Roussy, Villejuif, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moy</LastName><ForeName>Beverly</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital Cancer Center, Boston, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Iwata</LastName><ForeName>Hiroji</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Aichi Cancer Center, Chikusa-ku, Nagoya, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>von Minckwitz</LastName><ForeName>Gunter</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Luisenkrankenhaus, German Breast Group Forschungs GmbH, Düsseldorf, Neulsenburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chia</LastName><ForeName>Stephen K L</ForeName><Initials>SKL</Initials><AffiliationInfo><Affiliation>BC Cancer Agency, Vancouver, BC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mansi</LastName><ForeName>Janine</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Guy's and St Thomas' Hospital National Health Service Foundation Trust and Biomedical Research Centre, King's College, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barrios</LastName><ForeName>Carlos H</ForeName><Initials>CH</Initials><AffiliationInfo><Affiliation>Pontifical Catholic University of Rio Grande do Sul School of Medicine, Porto Alegre, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gnant</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Surgery and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tomašević</LastName><ForeName>Zorica</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Daily Chemotherapy Hospital, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Denduluri</LastName><ForeName>Neelima</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Virginia Cancer Specialists, Arlington, VA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Šeparović</LastName><ForeName>Robert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>University Hospital for Tumors, University Hospital Center "Sestre milosrdnice", Zagreb, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gokmen</LastName><ForeName>Erhan</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Ege University Faculty of Medicine, Izmir, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bashford</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Auckland Hospital, Auckland, New Zealand.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ruiz Borrego</LastName><ForeName>Manuel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Oncology Department, Hospital Universitario Virgen del Rocio, Seville, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Sung-Bae</ForeName><Initials>SB</Initials><AffiliationInfo><Affiliation>Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jakobsen</LastName><ForeName>Erik Hugger</ForeName><Initials>EH</Initials><AffiliationInfo><Affiliation>Department of Oncology, Lillebaelt Hospital, Vejle, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ciceniene</LastName><ForeName>Audrone</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Oncology Institute of Vilnius University, Vilnius, Lithuania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Inoue</LastName><ForeName>Kenichi</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Breast Oncology, Saitama Cancer Center, Kita-Adachi, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Overkamp</LastName><ForeName>Friedrich</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Oncologianova GmbH, Recklinghausen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heijns</LastName><ForeName>Joan B</ForeName><Initials>JB</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, Amphia Hospital, Breda, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Armstrong</LastName><ForeName>Anne C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Department of Oncology, Christie Hospital Manchester, Manchester, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Link</LastName><ForeName>John S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Breastlink Medical Group Inc, Santa Ana, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Joy</LastName><ForeName>Anil Abraham</ForeName><Initials>AA</Initials><AffiliationInfo><Affiliation>University of Alberta, Department of Oncology, Cross Cancer Institute, Edmonton, AB, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bryce</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wong</LastName><ForeName>Alvin</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moran</LastName><ForeName>Susan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yao</LastName><ForeName>Bin</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xu</LastName><ForeName>Feng</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Auerbach</LastName><ForeName>Alan</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Puma Biotechnology Inc, Los Angeles, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buyse</LastName><ForeName>Marc</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>International Drug Development Institute, Louvain-la-Neuve, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>Arlene</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Breast Cancer Research Centre-Western Australia, Perth, WA, Australia; Curtin University, Perth, WA, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>ExteNET Study Group</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>11</Month><Day>13</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Lancet Oncol</MedlineTA><NlmUniqueID>100957246</NlmUniqueID><ISSNLinking>1470-2045</ISSNLinking></MedlineJournalInfo><InvestigatorList><Investigator ValidYN="Y"><LastName>Harvey</LastName><ForeName>Vernon</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tomek</LastName><ForeName>Rudolf</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Robert</LastName><ForeName>Nicholas J</ForeName><Initials>NJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gore</LastName><ForeName>Ira</ForeName><Initials>I</Initials><Suffix>Jr</Suffix></Investigator><Investigator ValidYN="Y"><LastName>Smith</LastName><ForeName>John W</ForeName><Initials>JW</Initials><Suffix>2nd</Suffix></Investigator><Investigator ValidYN="Y"><LastName>Masuda</LastName><ForeName>Norikazu</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Di Sean Kendall</LastName><ForeName>S</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Harker</LastName><ForeName>William Graydon</ForeName><Initials>WG</Initials></Investigator><Investigator ValidYN="Y"><LastName>Petrakova</LastName><ForeName>Katarina</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Guerrero Zotano</LastName><ForeName>Angel</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Simon</LastName><ForeName>Amparo Ruiz</ForeName><Initials>AR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Konstantinovic</LastName><ForeName>Zora Neskovic</ForeName><Initials>ZN</Initials></Investigator><Investigator ValidYN="Y"><LastName>Iannotti</LastName><ForeName>Nicholas O</ForeName><Initials>NO</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tassone</LastName><ForeName>Pierfrancesco</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rodriguez</LastName><ForeName>Gladys I</ForeName><Initials>GI</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jáñez Martinez</LastName><ForeName>Noelia</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Crespo Massieu</LastName><ForeName>Carmen</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Smickoska</LastName><ForeName>Snezana</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Somali</LastName><ForeName>Isil</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yilmaz</LastName><ForeName>Ugur</ForeName><Initials>U</Initials></Investigator><Investigator ValidYN="Y"><LastName>Alonso</LastName><ForeName>Mirta Garcia</ForeName><Initials>MG</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rosales</LastName><ForeName>Adolfo Murias</ForeName><Initials>AM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cold</LastName><ForeName>Soeren</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Knoop</LastName><ForeName>Ann Soegaard</ForeName><Initials>AS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Patt</LastName><ForeName>Debra</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hellerstedt</LastName><ForeName>Beth A</ForeName><Initials>BA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Morales Murillo</LastName><ForeName>Serafin</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mayer</LastName><ForeName>Ingrid A</ForeName><Initials>IA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Means-Powell</LastName><ForeName>Julie Ann</ForeName><Initials>JA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hui</LastName><ForeName>Rina</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Senecal</LastName><ForeName>Francis M</ForeName><Initials>FM</Initials></Investigator><Investigator ValidYN="Y"><LastName>De Boer</LastName><ForeName>Richard Hendry</ForeName><Initials>RH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Shen</LastName><ForeName>Zhenzhou</ForeName><Initials>Z</Initials></Investigator><Investigator ValidYN="Y"><LastName>Luczak</LastName><ForeName>Adam Andrzej</ForeName><Initials>AA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chui</LastName><ForeName>Joanna W Y</ForeName><Initials>JWY</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tsang</LastName><ForeName>Janice Wing-Hang</ForeName><Initials>JW</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lang</LastName><ForeName>Istvan</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rai</LastName><ForeName>Yoshiaki</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hozumi</LastName><ForeName>Yasuo</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ten Tije</LastName><ForeName>Albert J</ForeName><Initials>AJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bhandari</LastName><ForeName>Manish</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Osborne</LastName><ForeName>Cynthia R C</ForeName><Initials>CRC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ohtani</LastName><ForeName>Shoichiro</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Higaki</LastName><ForeName>Kenji</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Watanabe</LastName><ForeName>Kenichi</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Taguchi</LastName><ForeName>Kazunori</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Takahashi</LastName><ForeName>Masato</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Filipovic</LastName><ForeName>Sladjana</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hansen</LastName><ForeName>Vincent L</ForeName><Initials>VL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rao</LastName><ForeName>Vijayarama Phooshkooru</ForeName><Initials>VP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gupta</LastName><ForeName>Manish</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Petrov</LastName><ForeName>Petar</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Coudert</LastName><ForeName>Bruno</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vojnovic</LastName><ForeName>Zeljko</ForeName><Initials>Z</Initials></Investigator><Investigator ValidYN="Y"><LastName>Polya</LastName><ForeName>Zsofia</ForeName><Initials>Z</Initials></Investigator><Investigator ValidYN="Y"><LastName>Miyaki</LastName><ForeName>Toshiko</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yamamoto</LastName><ForeName>Naohito</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Brincat</LastName><ForeName>Stephen</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lesniewski-Kmak</LastName><ForeName>Krzysztof</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chmielowska</LastName><ForeName>Ewa</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Birhiray</LastName><ForeName>Ruemu E</ForeName><Initials>RE</Initials></Investigator><Investigator ValidYN="Y"><LastName>Citron</LastName><ForeName>Marc L</ForeName><Initials>ML</Initials></Investigator><Investigator ValidYN="Y"><LastName>Papish</LastName><ForeName>Steven William</ForeName><Initials>SW</Initials></Investigator><Investigator ValidYN="Y"><LastName>Berry</LastName><ForeName>William R</ForeName><Initials>WR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Langkjer</LastName><ForeName>Sven Tyge</ForeName><Initials>ST</Initials></Investigator><Investigator ValidYN="Y"><LastName>Garcia Sáenz</LastName><ForeName>José Angel</ForeName><Initials>JA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Arance</LastName><ForeName>Ana Maria</ForeName><Initials>AM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Efrat</LastName><ForeName>Noa</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sarosiek</LastName><ForeName>Tomasz</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Grzeda</LastName><ForeName>Lukasz</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Manalo</LastName><ForeName>Yvonne</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Smith</LastName><ForeName>Julie C</ForeName><Initials>JC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vaziri</LastName><ForeName>Irfan</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Healey</LastName><ForeName>Tabitha</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rahim</LastName><ForeName>Yasmin</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Luk</LastName><ForeName>Cynthia</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dingle</LastName><ForeName>Brian</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Franco</LastName><ForeName>Sandra</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sorensen</LastName><ForeName>Peter Grundtvig</ForeName><Initials>PG</Initials></Investigator><Investigator ValidYN="Y"><LastName>Anand</LastName><ForeName>Anjana</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Khan</LastName><ForeName>Sarah</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Fountzilas</LastName><ForeName>George</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Aogi</LastName><ForeName>Kenjiro</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Shimizu</LastName><ForeName>Satoru</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mikulova</LastName><ForeName>Milada</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Spanik</LastName><ForeName>Stanislav</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Somer</LastName><ForeName>Robert A</ForeName><Initials>RA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Flynn</LastName><ForeName>Patrick J</ForeName><Initials>PJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Coward</LastName><ForeName>Jermaine</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mainwaring</LastName><ForeName>Paul</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jerusalem</LastName><ForeName>Guy</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Segura-Ojezzar</LastName><ForeName>Carine</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Levy</LastName><ForeName>Christelle</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Delozier</LastName><ForeName>Thierry</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Khayat</LastName><ForeName>David</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Coleman</LastName><ForeName>Robert E</ForeName><Initials>RE</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rolles</LastName><ForeName>Martin J</ForeName><Initials>MJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Maisano</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nardi</LastName><ForeName>Mario</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ito</LastName><ForeName>Yoshinori</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yumuk</LastName><ForeName>Perran Fulden</ForeName><Initials>PF</Initials></Investigator><Investigator ValidYN="Y"><LastName>Basaran</LastName><ForeName>Gul</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Serdar Turhal</LastName><ForeName>Nazim</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wilkinson</LastName><ForeName>Mary J</ForeName><Initials>MJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Green</LastName><ForeName>Nathan B</ForeName><Initials>NB</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sidrys</LastName><ForeName>Algis P</ForeName><Initials>AP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hallmeyer</LastName><ForeName>Sigrun</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Testori</LastName><ForeName>Douglas J</ForeName><Initials>DJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sridhar</LastName><ForeName>Srikala</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chang</LastName><ForeName>Jose</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sun</LastName><ForeName>Qiang</ForeName><Initials>Q</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jara-Sanchez</LastName><ForeName>Carlos</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rubio</LastName><ForeName>Xabier</ForeName><Initials>X</Initials></Investigator><Investigator ValidYN="Y"><LastName>Garrido</LastName><ForeName>Maria Lomas</ForeName><Initials>ML</Initials></Investigator><Investigator ValidYN="Y"><LastName>De La Haba Rodriguez</LastName><ForeName>Juan Rafael</ForeName><Initials>JR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Perello Martorell</LastName><ForeName>Antonia</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Avelia Mestre</LastName><ForeName>Antoni</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rifa Ferrer</LastName><ForeName>Julio</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Del Barco Berron</LastName><ForeName>Sonia</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nagy</LastName><ForeName>Zsuzsanna</ForeName><Initials>Z</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tanaka</LastName><ForeName>Maki</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Im</LastName><ForeName>Young-Hyuck</ForeName><Initials>YH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Carroll</LastName><ForeName>Robert R</ForeName><Initials>RR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dickerson</LastName><ForeName>Laura C</ForeName><Initials>LC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mace</LastName><ForeName>Joseph R</ForeName><Initials>JR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rivera</LastName><ForeName>Ragene</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Klein</LastName><ForeName>Leonard M</ForeName><Initials>LM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ruxer</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wilks</LastName><ForeName>Sharon T</ForeName><Initials>ST</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kotasek</LastName><ForeName>Dusan</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Popov</LastName><ForeName>Vasil</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Taskova</LastName><ForeName>Violina</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Marinova-Venkova</LastName><ForeName>Violetka</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Timcheva</LastName><ForeName>Constanta</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Desbiens</LastName><ForeName>Christine</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ayoub</LastName><ForeName>Jean-Pierre</ForeName><Initials>JP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Grenier</LastName><ForeName>Debjani</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Marschner</LastName><ForeName>Norbert</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tesch</LastName><ForeName>Hans</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lueck</LastName><ForeName>Hans-Joachim</ForeName><Initials>HJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Janssen</LastName><ForeName>Jan</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schwaner</LastName><ForeName>Ingo</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wahlstrom</LastName><ForeName>Stine</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Brix</LastName><ForeName>Eva Harder</ForeName><Initials>EH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vallentin</LastName><ForeName>Susanne</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kristensen</LastName><ForeName>Dan</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Andreeva</LastName><ForeName>Anna</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Glavicic</LastName><ForeName>Vesna</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Calvo Plaza</LastName><ForeName>Isabel</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Anton Torres</LastName><ForeName>Antonio</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Veyret</LastName><ForeName>Corinne</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bergerat</LastName><ForeName>Jean-Pierre</ForeName><Initials>JP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bourbouloux</LastName><ForeName>Emmanuelle</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ella</LastName><ForeName>Wendy Ann</ForeName><Initials>WA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Algurafi</LastName><ForeName>Hafiz</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Robinson</LastName><ForeName>Anne</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kim</LastName><ForeName>Seung Jin</ForeName><Initials>SJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Taguchi</LastName><ForeName>Tetsuya</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Juozaityte</LastName><ForeName>Elona</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Madretsma</LastName><ForeName>Stanley</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Radema</LastName><ForeName>Sandra</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Czerniawska-Meier</LastName><ForeName>Malgorzata</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rogowski</LastName><ForeName>Wojciech</ForeName><Initials>W</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wagnerova</LastName><ForeName>Maria</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Richards</LastName><ForeName>Donald A</ForeName><Initials>DA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tan-Chiu</LastName><ForeName>Elizabeth</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vasileios</LastName><ForeName>Asskikis</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Henderson</LastName><ForeName>Charles Arthur</ForeName><Initials>CA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Holden</LastName><ForeName>Viran Roger</ForeName><Initials>VR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wang</LastName><ForeName>Xiaojia</ForeName><Initials>X</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tong</LastName><ForeName>Zhongsheng</ForeName><Initials>Z</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yang</LastName><ForeName>Junlan</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gonzalez</LastName><ForeName>Manuel Enrique</ForeName><Initials>ME</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rezai</LastName><ForeName>Mahdi</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hackmann</LastName><ForeName>John</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>de Dueñas</LastName><ForeName>Eduardo Martinez</ForeName><Initials>EM</Initials></Investigator><Investigator ValidYN="Y"><LastName>de Las Heras</LastName><ForeName>Begoña Bermejo</ForeName><Initials>BB</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dourthe</LastName><ForeName>Louis Marie</ForeName><Initials>LM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chocteau-Bouju</LastName><ForeName>Dorothee</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bougnoux</LastName><ForeName>Philippe</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kakolyris</LastName><ForeName>Stylianos</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kalofonos</LastName><ForeName>Haralabos</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pectasidis</LastName><ForeName>Dimitrios</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ng</LastName><ForeName>Ting Ying</ForeName><Initials>TY</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pajkos</LastName><ForeName>Gabor</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Somogyine</LastName><ForeName>Eva Ezer</ForeName><Initials>EE</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tonini</LastName><ForeName>Giuseppe</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Giuffrida</LastName><ForeName>Dario</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Takao</LastName><ForeName>Shintaro</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ishitobi</LastName><ForeName>Makoto</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Inaji</LastName><ForeName>Hideo</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tokuda</LastName><ForeName>Yutaka</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wozniak</LastName><ForeName>Katarzyna</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lungulescu</LastName><ForeName>Dan</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lu</LastName><ForeName>Yen-Shen</ForeName><Initials>YS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chang</LastName><ForeName>King-Jen</ForeName><Initials>KJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hill</LastName><ForeName>Julian</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Croot</LastName><ForeName>Christopher Charles</ForeName><Initials>CC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dekker</LastName><ForeName>Albert</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Belman</LastName><ForeName>Neil D</ForeName><Initials>ND</Initials></Investigator><Investigator ValidYN="Y"><LastName>Conde</LastName><ForeName>Miguel</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Michaelson</LastName><ForeName>Richard A</ForeName><Initials>RA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kemmer</LastName><ForeName>Kathleen</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chui</LastName><ForeName>Stephen</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Luoh</LastName><ForeName>Shiuh-Wen</ForeName><Initials>SW</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nahum</LastName><ForeName>Kenneth</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Greenspan</LastName><ForeName>Andrew R</ForeName><Initials>AR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nichols</LastName><ForeName>Joni C</ForeName><Initials>JC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Encarnacion</LastName><ForeName>Carlos A</ForeName><Initials>CA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Niederman</LastName><ForeName>Thomas M J</ForeName><Initials>TMJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lee</LastName><ForeName>Theresa</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Alexander</LastName><ForeName>Roland</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gordon</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tomova</LastName><ForeName>Antoanet</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rauch</LastName><ForeName>Daniel</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Popescu</LastName><ForeName>Razvan Andrei</ForeName><Initials>RA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rojas</LastName><ForeName>Gustavo Adolfo</ForeName><Initials>GA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vanasek</LastName><ForeName>Jaroslav</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Neunhoeffer</LastName><ForeName>Tanja</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Barinoff</LastName><ForeName>Jana</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Graffunder</LastName><ForeName>Gerd</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wolfgang</LastName><ForeName>Abenhardt</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bojko</LastName><ForeName>Peter</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Heinrich</LastName><ForeName>Bernhard</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>von der Assen</LastName><ForeName>Albert</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Antonovic</LastName><ForeName>Bogovic Jurij</ForeName><Initials>BJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Adrian</LastName><ForeName>Lene</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ramos Vazquez</LastName><ForeName>Manuel</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gonzalez Santiago</LastName><ForeName>Santiago</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dieras</LastName><ForeName>Veronique</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bishop</LastName><ForeName>Jill Mercia</ForeName><Initials>JM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Perren</LastName><ForeName>Timothy John</ForeName><Initials>TJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Varthalitis</LastName><ForeName>Ioannis</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mavroudis</LastName><ForeName>Dimitris</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Georgoulias</LastName><ForeName>Vassilis</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chow</LastName><ForeName>Louis W C</ForeName><Initials>LWC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yau</LastName><ForeName>Chung Cheung Thomas</ForeName><Initials>CCT</Initials></Investigator><Investigator ValidYN="Y"><LastName>Liang</LastName><ForeName>Raymond Hin-Suen</ForeName><Initials>RH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pikó</LastName><ForeName>Béla</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wéber</LastName><ForeName>Agnes</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kaufman</LastName><ForeName>Bella</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Drumea</LastName><ForeName>Karen</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nuzzo</LastName><ForeName>Francesco</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>De Matteis</LastName><ForeName>Andrea</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nuzzo</LastName><ForeName>Francesco</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Carteni</LastName><ForeName>Giacomo</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tokunaga</LastName><ForeName>Eriko</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ishida</LastName><ForeName>Mayumi</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ohno</LastName><ForeName>Shinji</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sato</LastName><ForeName>Nobuaki</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kuroi</LastName><ForeName>Katsumasa</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nishimura</LastName><ForeName>Reiki</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Watanabe</LastName><ForeName>Junichiro</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Choi</LastName><ForeName>Yoon Ji</ForeName><Initials>YJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Park</LastName><ForeName>Kyong Hwa</ForeName><Initials>KH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wojtukiewicz</LastName><ForeName>Marek</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jassem</LastName><ForeName>Jacek</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Loman</LastName><ForeName>Niklas</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Askoy</LastName><ForeName>Sercan</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Altundag</LastName><ForeName>Mustafa Kadri</ForeName><Initials>MK</Initials></Investigator><Investigator ValidYN="Y"><LastName>Saip</LastName><ForeName>Pinar</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ali</LastName><ForeName>Muhammad Amjad</ForeName><Initials>MA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wade Iii</LastName><ForeName>James Lloyd</ForeName><Initials>JL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chien</LastName><ForeName>Amy Jo</ForeName><Initials>AJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Brandt</LastName><ForeName>Debra</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Novik</LastName><ForeName>Yelena</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jani</LastName><ForeName>Chirag</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rice</LastName><ForeName>Robert L</ForeName><Initials>RL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gaffar</LastName><ForeName>Yousuf A R</ForeName><Initials>YAR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Keaton</LastName><ForeName>Mark R</ForeName><Initials>MR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bajaj</LastName><ForeName>Rajesh</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kimmick</LastName><ForeName>Gretchen</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Campbell</LastName><ForeName>David</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>De Boer</LastName><ForeName>Richard Hendry</ForeName><Initials>RH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Turnquest</LastName><ForeName>Theodore</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lucas</LastName><ForeName>Sideras</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dube</LastName><ForeName>Pierre</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Xu</LastName><ForeName>Binghe</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schilling</LastName><ForeName>Joerg</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Apel</LastName><ForeName>Klaus</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sorensen</LastName><ForeName>Peter Grundtvig</ForeName><Initials>PG</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vestlev</LastName><ForeName>Peter Michael</ForeName><Initials>PM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jensen</LastName><ForeName>Brita Bjerregaard</ForeName><Initials>BB</Initials></Investigator><Investigator ValidYN="Y"><LastName>Haahr</LastName><ForeName>Vera</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lescure</LastName><ForeName>Alvaro Rodriguez</ForeName><Initials>AR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Grana Suarez</LastName><ForeName>Begona</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Saura Manich</LastName><ForeName>Cristina</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jacquin</LastName><ForeName>Jean-Philippe</ForeName><Initials>JP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Samreen</LastName><ForeName>Ahmed</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Boiangiu</LastName><ForeName>Ion</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dank</LastName><ForeName>Magdolna</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Falci</LastName><ForeName>Cristina</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jirillo</LastName><ForeName>Antonio</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cinieri</LastName><ForeName>Saverio</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ueno</LastName><ForeName>Takayuki</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sato</LastName><ForeName>Fumiaki</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yamashiro</LastName><ForeName>Hiroyasu</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sugie</LastName><ForeName>Tomoharu</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lee</LastName><ForeName>Keun Seok</ForeName><Initials>KS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ro</LastName><ForeName>Jung Sil</ForeName><Initials>JS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Park</LastName><ForeName>In Hae</ForeName><Initials>IH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bustam</LastName><ForeName>Anita Zarina</ForeName><Initials>AZ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Suszko-Kazarnowicz</LastName><ForeName>Malgorzata</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Piktel</LastName><ForeName>Artur</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Krzemieniecki</LastName><ForeName>Krzysztof</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Iorga</LastName><ForeName>Polizenia Georgeta</ForeName><Initials>PG</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yap</LastName><ForeName>Yoon Sim</ForeName><Initials>YS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kakalejcik</LastName><ForeName>Marian</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sevinc</LastName><ForeName>Alper</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ozguroglu</LastName><ForeName>Mustafa</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chen</LastName><ForeName>Shin-Cheh</ForeName><Initials>SC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Greenberg</LastName><ForeName>Richard H</ForeName><Initials>RH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Eisemann</LastName><ForeName>Allan Daniel</ForeName><Initials>AD</Initials></Investigator><Investigator ValidYN="Y"><LastName>Droder</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Abbasi</LastName><ForeName>M Rashid</ForeName><Initials>MR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vaysburd</LastName><ForeName>Marina</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Caldera</LastName><ForeName>Humberto Jose</ForeName><Initials>HJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Haley</LastName><ForeName>Barbara Bacsik</ForeName><Initials>BB</Initials></Investigator><Investigator ValidYN="Y"><LastName>Robin</LastName><ForeName>Erwin</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Inhorn</LastName><ForeName>Roger C</ForeName><Initials>RC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hufnagel</LastName><ForeName>David</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kenyon</LastName><ForeName>Peter D</ForeName><Initials>PD</Initials></Investigator><Investigator ValidYN="Y"><LastName>Spremulli</LastName><ForeName>Ellen</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Silverman</LastName><ForeName>Paula</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jain</LastName><ForeName>Sharad</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Weigand</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mebis</LastName><ForeName>Jeroen</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Koynova</LastName><ForeName>Tatyana</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lesperance</LastName><ForeName>Bernard</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Prausova</LastName><ForeName>Jana</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kohne</LastName><ForeName>Claus-Henning</ForeName><Initials>CH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schneeweiss</LastName><ForeName>Andreas</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jackisch</LastName><ForeName>Christian</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Fuxius</LastName><ForeName>Stefan</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cubedo Cervera</LastName><ForeName>Ricardo</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Urruticoechea Ribate</LastName><ForeName>Ander</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pernas Simon</LastName><ForeName>Sonia</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Valero Gallego</LastName><ForeName>Jose</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Arcusa Lanza</LastName><ForeName>Angels</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Del Pilar Alvarez</LastName><ForeName>Maria</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Florian Gerico</LastName><ForeName>Jesus</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cany</LastName><ForeName>Laurent</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Stebbing</LastName><ForeName>Justin</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Labudovic</LastName><ForeName>Dejan</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gugic</LastName><ForeName>Damir</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vrbanec</LastName><ForeName>Damir</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Roila</LastName><ForeName>Fausto</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Barni</LastName><ForeName>Sandro</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bidoli</LastName><ForeName>Paolo</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mukai</LastName><ForeName>Hirofumi</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bermudez</LastName><ForeName>Vanessa</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Eniu</LastName><ForeName>Alexandru</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mirtsching</LastName><ForeName>Barry C</ForeName><Initials>BC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ibrahim</LastName><ForeName>Emad</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Trey</LastName><ForeName>Joan</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hergenroeder</LastName><ForeName>Paul Francis</ForeName><Initials>PF</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mahmood</LastName><ForeName>Aftab</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gonzalez</LastName><ForeName>Anneliese</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kaplan</LastName><ForeName>Edward H</ForeName><Initials>EH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ban</LastName><ForeName>Stacy</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Patel</LastName><ForeName>Dhimant</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Clowney</LastName><ForeName>Billy</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hoelzer</LastName><ForeName>Karen</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schwartz</LastName><ForeName>Garry H</ForeName><Initials>GH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Salkeni</LastName><ForeName>Mohamed</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Abraham</LastName><ForeName>Jame</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Narula</LastName><ForeName>Sunil</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jabboury</LastName><ForeName>Khaled</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mocharnuk</LastName><ForeName>Robert Scott</ForeName><Initials>RS</Initials></Investigator><Investigator ValidYN="Y"><LastName>McDonough</LastName><ForeName>Richard H</ForeName><Initials>RH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sikes</LastName><ForeName>David H</ForeName><Initials>DH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kawanchi</LastName><ForeName>Ronald H</ForeName><Initials>RH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schlabach</LastName><ForeName>Larry</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>McCachren</LastName><ForeName>Samuel Spence</ForeName><Initials>SS</Initials><Suffix>Jr</Suffix></Investigator><Investigator ValidYN="Y"><LastName>Cosgriff</LastName><ForeName>Thomas M</ForeName><Initials>TM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dreisbach</LastName><ForeName>Luke</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>DeMichele</LastName><ForeName>Angela</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pawl</LastName><ForeName>Lawrence</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lucas</LastName><ForeName>Jennifer</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Shinn</LastName><ForeName>Lowell C</ForeName><Initials>LC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Alkhouri</LastName><ForeName>Nabiel</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Monga</LastName><ForeName>Manish</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lindquist</LastName><ForeName>Deborah L</ForeName><Initials>DL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Anderson</LastName><ForeName>Thomas C</ForeName><Initials>TC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Khurshid</LastName><ForeName>Humera</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Witherby</LastName><ForeName>Sabrina</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Erickson</LastName><ForeName>Nicholette</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Traynor</LastName><ForeName>Ann</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bose</LastName><ForeName>Ron</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pluard</LastName><ForeName>Timothy J</ForeName><Initials>TJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jones</LastName><ForeName>Michael C</ForeName><Initials>MC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Prakash</LastName><ForeName>Sucharu</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Volterra</LastName><ForeName>Fabio</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Capo</LastName><ForeName>Gerardo</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Flaherty</LastName><ForeName>Lawrence E</ForeName><Initials>LE</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gartner</LastName><ForeName>Elaina</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Baidas</LastName><ForeName>Said</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Okazaki</LastName><ForeName>Ian</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nguyen</LastName><ForeName>Bichlien</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rakowski</LastName><ForeName>Thomas</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Oliff</LastName><ForeName>Ira</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Leach</LastName><ForeName>Joseph W</ForeName><Initials>JW</Initials></Investigator><Investigator ValidYN="Y"><LastName>Anderson</LastName><ForeName>Daniel</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kubiak</LastName><ForeName>Kendra</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tsai</LastName><ForeName>Michaela</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vroman</LastName><ForeName>Philippe</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Deleu</LastName><ForeName>Ines</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lybaert</LastName><ForeName>Willem</ForeName><Initials>W</Initials></Investigator><Investigator ValidYN="Y"><LastName>Borms</LastName><ForeName>Marleen</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Couture</LastName><ForeName>Felix</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wilson</LastName><ForeName>Jonathan J</ForeName><Initials>JJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hunt</LastName><ForeName>Gordon</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Holland</LastName><ForeName>David R</ForeName><Initials>DR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mingrone</LastName><ForeName>Walter</ForeName><Initials>W</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wang</LastName><ForeName>Shusen</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Liu</LastName><ForeName>Donggeng</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jiang</LastName><ForeName>Zefei</ForeName><Initials>Z</Initials></Investigator><Investigator ValidYN="Y"><LastName>Benesova</LastName><ForeName>Vera</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Smakal</LastName><ForeName>Martin</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Garnolova</LastName><ForeName>Petra</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vesper</LastName><ForeName>Anne-Sophie</ForeName><Initials>AS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Neumann</LastName><ForeName>Monika</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Janni</LastName><ForeName>Wolfgang</ForeName><Initials>W</Initials></Investigator><Investigator ValidYN="Y"><LastName>Liedtke</LastName><ForeName>Cornelia</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Fischer</LastName><ForeName>Dorothea</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Grischke</LastName><ForeName>Eva-Maria</ForeName><Initials>EM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Seeger</LastName><ForeName>Dietmar</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Moebus</LastName><ForeName>Volker</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Prechtl</LastName><ForeName>Anita</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Carlos Camara Toral</LastName><ForeName>Juan</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sanchez Munoz</LastName><ForeName>Alfonso</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gonzalez Jimenez</LastName><ForeName>Sonia</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cassinello Espinosa</LastName><ForeName>Javier</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cirauqui</LastName><ForeName>Beatriz</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Margeli Vila</LastName><ForeName>Mireia</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Batista Lopez</LastName><ForeName>Norberto</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chacon Lopez-Muniz</LastName><ForeName>Jose Ignacio</ForeName><Initials>JI</Initials></Investigator><Investigator ValidYN="Y"><LastName>de la Cruz Mora</LastName><ForeName>Miguel Angel</ForeName><Initials>MA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mailliez</LastName><ForeName>Audrey</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vanlemmens</LastName><ForeName>Laurence</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pouessel</LastName><ForeName>Damien</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Espie</LastName><ForeName>Marc</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Conibear</LastName><ForeName>John</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Roylance</LastName><ForeName>Rebecca</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Harnett</LastName><ForeName>Adrian</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Geffen</LastName><ForeName>David</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ruggeri</LastName><ForeName>Enzo Maria</ForeName><Initials>EM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gamucci</LastName><ForeName>Teresa</ForeName><Initials>T</Initials></Investigator><Investigator ValidYN="Y"><LastName>Van Groeningen</LastName><ForeName>Cees J</ForeName><Initials>CJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Banas</LastName><ForeName>Renata</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Loman</LastName><ForeName>Niklas</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Alkis</LastName><ForeName>Necati</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hou</LastName><ForeName>Ming-Feng</ForeName><Initials>MF</Initials></Investigator><Investigator ValidYN="Y"><LastName>Krie</LastName><ForeName>Amy K</ForeName><Initials>AK</Initials></Investigator><Investigator ValidYN="Y"><LastName>Vrindavanam</LastName><ForeName>Nandagopal S</ForeName><Initials>NS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Howard</LastName><ForeName>Orion M</ForeName><Initials>OM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Citrin</LastName><ForeName>Dennis</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Morginstin</LastName><ForeName>Mark S</ForeName><Initials>MS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Desai</LastName><ForeName>Ajit</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sanchez</LastName><ForeName>Ines J</ForeName><Initials>IJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nixon</LastName><ForeName>David Allen</ForeName><Initials>DA</Initials><Suffix>Jr</Suffix></Investigator><Investigator ValidYN="Y"><LastName>Beatty</LastName><ForeName>Patrick G</ForeName><Initials>PG</Initials></Investigator><Investigator ValidYN="Y"><LastName>Edmiston</LastName><ForeName>Kathryn</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>McLaughlin</LastName><ForeName>Marilyn</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Eneman</LastName><ForeName>Jonathan D</ForeName><Initials>JD</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lynch</LastName><ForeName>Cynthia A</ForeName><Initials>CA</Initials></Investigator><Investigator ValidYN="Y"><LastName>O'Brien</LastName><ForeName>Edward</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Call</LastName><ForeName>Justin A</ForeName><Initials>JA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lanier</LastName><ForeName>Keith S</ForeName><Initials>KS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Conlin</LastName><ForeName>Alison</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Brooks</LastName><ForeName>Donald J</ForeName><Initials>DJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>McIntyre</LastName><ForeName>Kristi</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Saltzman</LastName><ForeName>Marc A</ForeName><Initials>MA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Castine</LastName><ForeName>Michael J</ForeName><Initials>MJ</Initials><Suffix>3rd</Suffix></Investigator><Investigator ValidYN="Y"><LastName>Ortega</LastName><ForeName>Gregory L</ForeName><Initials>GL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Choi</LastName><ForeName>Young M</ForeName><Initials>YM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Reynolds</LastName><ForeName>Craig H</ForeName><Initials>CH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Brescia</LastName><ForeName>Frankie Ann</ForeName><Initials>FA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kramer</LastName><ForeName>Rita</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kohn</LastName><ForeName>Aimee D</ForeName><Initials>AD</Initials></Investigator><Investigator ValidYN="Y"><LastName>Micha</LastName><ForeName>John P</ForeName><Initials>JP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rhee</LastName><ForeName>Jessica M</ForeName><Initials>JM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Shah</LastName><ForeName>Satish</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Riseberg</LastName><ForeName>David A</ForeName><Initials>DA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Patterson</LastName><ForeName>William Kevin</ForeName><Initials>WK</Initials></Investigator><Investigator ValidYN="Y"><LastName>Salmon</LastName><ForeName>Jean-Paul</ForeName><Initials>JP</Initials></Investigator><Investigator ValidYN="Y"><LastName>Andre</LastName><ForeName>Chantal</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bols</LastName><ForeName>Alain</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>D'hondt</LastName><ForeName>Randal</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Luce</LastName><ForeName>Sylvie</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nouwynck</LastName><ForeName>Claire</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pelgrims</LastName><ForeName>Gino</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Richard</LastName><ForeName>Vincent</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Verschuere</LastName><ForeName>Johan</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Geldhof</LastName><ForeName>Kurt</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Caspar</LastName><ForeName>Clemens</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Luo</LastName><ForeName>Rongcheng</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bednarik</LastName><ForeName>Otakar</ForeName><Initials>O</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schwedler</LastName><ForeName>Kathrin</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Marcus</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Neumeister</LastName><ForeName>Romy</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bischoff</LastName><ForeName>Joachim</ForeName><Initials>J</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rack</LastName><ForeName>Brigitte</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Repp</LastName><ForeName>Roland</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Fries</LastName><ForeName>Stefan</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Adrion</LastName><ForeName>Ralf</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schulz</LastName><ForeName>Volker</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Klare</LastName><ForeName>Peter</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Danei</LastName><ForeName>Mahmoud</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ossenbuhl</LastName><ForeName>Dirk</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kusche</LastName><ForeName>Jakob Manfred</ForeName><Initials>JM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Griesinger</LastName><ForeName>Frank</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Baena Canada</LastName><ForeName>Jose Manuel</ForeName><Initials>JM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Martinez Del Prado</LastName><ForeName>Purificacion</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Machover</LastName><ForeName>David</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mayeur</LastName><ForeName>Didier</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Trufflandier</LastName><ForeName>Nathalie</ForeName><Initials>N</Initials></Investigator><Investigator ValidYN="Y"><LastName>Delecroix</LastName><ForeName>Valerie</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mousseau</LastName><ForeName>Mireille</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Mouret-Reynier</LastName><ForeName>Marie-Ange</ForeName><Initials>MA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Nabholtz</LastName><ForeName>Jean-Marc</ForeName><Initials>JM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chetiyawardana</LastName><ForeName>Anula D</ForeName><Initials>AD</Initials></Investigator><Investigator ValidYN="Y"><LastName>Papandreou</LastName><ForeName>Christos</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Hornyak</LastName><ForeName>Lajos</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Faluhelyi</LastName><ForeName>Zsolt</ForeName><Initials>Z</Initials></Investigator><Investigator ValidYN="Y"><LastName>Simo</LastName><ForeName>Erzsebet</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Di Palma</LastName><ForeName>Mario</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Cognetti</LastName><ForeName>Francesco</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gorzegno</LastName><ForeName>Gabriella</ForeName><Initials>G</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dogliotti</LastName><ForeName>Luigi</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gridelli</LastName><ForeName>Cesare</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Falcone</LastName><ForeName>Alfredo</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Soto Parra</LastName><ForeName>Hector</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Buscarino</LastName><ForeName>Calogero</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Im</LastName><ForeName>Seock-Ah</ForeName><Initials>SA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sanchez Llamas</LastName><ForeName>Benito</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Dercksen</LastName><ForeName>Wouter</ForeName><Initials>W</Initials></Investigator><Investigator ValidYN="Y"><LastName>Erdkamp</LastName><ForeName>Franciscus</ForeName><Initials>F</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ruit</LastName><ForeName>Jan B</ForeName><Initials>JB</Initials></Investigator><Investigator ValidYN="Y"><LastName>Braun</LastName><ForeName>Hans</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Portielje</LastName><ForeName>Joanneke E A</ForeName><Initials>JEA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ciltas</LastName><ForeName>Aydin</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Buyukberber</LastName><ForeName>Suleyman</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Benekli</LastName><ForeName>Mustafa</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Zahalsky</LastName><ForeName>Andrew J</ForeName><Initials>AJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jaslow</LastName><ForeName>Rebecca</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Thomas</LastName><ForeName>Gary W</ForeName><Initials>GW</Initials></Investigator><Investigator ValidYN="Y"><LastName>Maini</LastName><ForeName>Archana</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wiznitzer</LastName><ForeName>Israel</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Khojasteh</LastName><ForeName>Ali</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Francisco Gonzalez</LastName><ForeName>Manuel</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kong</LastName><ForeName>Lynn R</ForeName><Initials>LR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Padmanabhan</LastName><ForeName>Aruna</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Conkright</LastName><ForeName>William A</ForeName><Initials>WA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Swain</LastName><ForeName>Sandra M</ForeName><Initials>SM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Faig</LastName><ForeName>Douglas E</ForeName><Initials>DE</Initials></Investigator><Investigator ValidYN="Y"><LastName>Jain</LastName><ForeName>Kirti</ForeName><Initials>K</Initials></Investigator><Investigator ValidYN="Y"><LastName>Yanagihara</LastName><ForeName>Ronald H</ForeName><Initials>RH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ottaviano</LastName><ForeName>Yvonne</ForeName><Initials>Y</Initials></Investigator><Investigator ValidYN="Y"><LastName>Delmas</LastName><ForeName>Andrew</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Steele</LastName><ForeName>Heather A</ForeName><Initials>HA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rainey</LastName><ForeName>Gordon K</ForeName><Initials>GK</Initials></Investigator><Investigator ValidYN="Y"><LastName>Harris</LastName><ForeName>Penelope J</ForeName><Initials>PJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Burris</LastName><ForeName>Jason K</ForeName><Initials>JK</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rupard</LastName><ForeName>Erik J</ForeName><Initials>EJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tan</LastName><ForeName>Esther</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Whitworth</LastName><ForeName>Pat W</ForeName><Initials>PW</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bova</LastName><ForeName>Abby R</ForeName><Initials>AR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Anderson</LastName><ForeName>Ian C</ForeName><Initials>IC</Initials></Investigator><Investigator ValidYN="Y"><LastName>Shirinian</LastName><ForeName>Mihran</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Tin-U</LastName><ForeName>Caesar</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>O'Rourke</LastName><ForeName>Timothy J</ForeName><Initials>TJ</Initials></Investigator><Investigator ValidYN="Y"><LastName>Roberts</LastName><ForeName>Michael S</ForeName><Initials>MS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Francisco</LastName><ForeName>Michael</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Pierson</LastName><ForeName>A Scott</ForeName><Initials>AS</Initials></Investigator><Investigator ValidYN="Y"><LastName>Byeff</LastName><ForeName>Peter D</ForeName><Initials>PD</Initials></Investigator><Investigator ValidYN="Y"><LastName>Kovach</LastName><ForeName>Peter A</ForeName><Initials>PA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Caton</LastName><ForeName>John R</ForeName><Initials>JR</Initials><Suffix>Jr</Suffix></Investigator><Investigator ValidYN="Y"><LastName>Rarick</LastName><ForeName>Mark Urban</ForeName><Initials>MU</Initials></Investigator><Investigator ValidYN="Y"><LastName>Schimidt</LastName><ForeName>William G</ForeName><Initials>WG</Initials><Suffix>Jr</Suffix></Investigator><Investigator ValidYN="Y"><LastName>Stopeck</LastName><ForeName>Alison T</ForeName><Initials>AT</Initials></Investigator><Investigator ValidYN="Y"><LastName>Swart</LastName><ForeName>Rachel</ForeName><Initials>R</Initials></Investigator><Investigator ValidYN="Y"><LastName>Carrillo Flores</LastName><ForeName>Maria Regina</ForeName><Initials>MR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Alemany</LastName><ForeName>Carlos A</ForeName><Initials>CA</Initials></Investigator><Investigator ValidYN="Y"><LastName>Lozada</LastName><ForeName>Brennely</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Weinstein</LastName><ForeName>Paul L</ForeName><Initials>PL</Initials></Investigator><Investigator ValidYN="Y"><LastName>Wang</LastName><ForeName>Wei</ForeName><Initials>W</Initials></Investigator><Investigator ValidYN="Y"><LastName>Porubcin</LastName><ForeName>Michael</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ellison</LastName><ForeName>David M</ForeName><Initials>DM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Geils</LastName><ForeName>George F</ForeName><Initials>GF</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rivera</LastName><ForeName>Edgardo</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Charif</LastName><ForeName>Mahmoud</ForeName><Initials>M</Initials></Investigator></InvestigatorList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>08</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>08</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>09</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>11</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>11</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>11</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29146401</ArticleId><ArticleId IdType="pii">S1470-2045(17)30717-9</ArticleId><ArticleId IdType="doi">10.1016/S1470-2045(17)30717-9</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000004 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000004 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:29146401
|texte= Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:29146401" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |