Adoption of revised dosage recommendations for childhood tuberculosis in countries with different childhood tuberculosis burdens.
Identifieur interne : 003988 ( PubMed/Checkpoint ); précédent : 003987; suivant : 003989Adoption of revised dosage recommendations for childhood tuberculosis in countries with different childhood tuberculosis burdens.
Auteurs : A K Detjen [France] ; C. Macé [France] ; C. Perrin [France] ; S M Graham [Australie] ; M. Grzemska [Suisse]Source :
- Public health action [ 2220-8372 ] ; 2012.
Abstract
In 2010, the World Health Organization (WHO) published revised dosage recommendations for the treatment of tuberculosis (TB) in children. The aim of the survey was to assess whether countries adopt these new dosage recommendations, as well as to identify challenges in the management and treatment of childhood TB. In addition, countries were asked to provide 2010 surveillance data on childhood TB.
DOI: 10.5588/pha.12.0052
PubMed: 26392970
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Macé</name><affiliation wicri:level="3"><nlm:affiliation>The International Union Against Tuberculosis and Lung Disease, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>The International Union Against Tuberculosis and Lung Disease, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Perrin, C" sort="Perrin, C" uniqKey="Perrin C" first="C" last="Perrin">C. 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Macé</name><affiliation wicri:level="3"><nlm:affiliation>The International Union Against Tuberculosis and Lung Disease, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>The International Union Against Tuberculosis and Lung Disease, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Perrin, C" sort="Perrin, C" uniqKey="Perrin C" first="C" last="Perrin">C. Perrin</name><affiliation wicri:level="3"><nlm:affiliation>The International Union Against Tuberculosis and Lung Disease, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>The International Union Against Tuberculosis and Lung Disease, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Graham, S M" sort="Graham, S M" uniqKey="Graham S" first="S M" last="Graham">S M Graham</name><affiliation wicri:level="1"><nlm:affiliation>The International Union Against Tuberculosis and Lung Disease, Paris, France ; Centre for International Child Health, University of Melbourne Department of Paediatrics and Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The International Union Against Tuberculosis and Lung Disease, Paris, France ; Centre for International Child Health, University of Melbourne Department of Paediatrics and Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Grzemska, M" sort="Grzemska, M" uniqKey="Grzemska M" first="M" last="Grzemska">M. Grzemska</name><affiliation wicri:level="1"><nlm:affiliation>Stop TB Partnership, World Health Organization, Geneva, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Stop TB Partnership, World Health Organization, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author></analytic><series><title level="j">Public health action</title><idno type="ISSN">2220-8372</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In 2010, the World Health Organization (WHO) published revised dosage recommendations for the treatment of tuberculosis (TB) in children. The aim of the survey was to assess whether countries adopt these new dosage recommendations, as well as to identify challenges in the management and treatment of childhood TB. In addition, countries were asked to provide 2010 surveillance data on childhood TB.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">26392970</PMID><DateCreated><Year>2015</Year><Month>09</Month><Day>22</Day></DateCreated><DateCompleted><Year>2015</Year><Month>09</Month><Day>22</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>20</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">2220-8372</ISSN><JournalIssue CitedMedium="Print"><Volume>2</Volume><Issue>4</Issue><PubDate><Year>2012</Year><Month>Dec</Month><Day>21</Day></PubDate></JournalIssue><Title>Public health action</Title><ISOAbbreviation>Public Health Action</ISOAbbreviation></Journal><ArticleTitle>Adoption of revised dosage recommendations for childhood tuberculosis in countries with different childhood tuberculosis burdens.</ArticleTitle><Pagination><MedlinePgn>126-32</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.5588/pha.12.0052</ELocationID><Abstract><AbstractText Label="BACKGROUND AND OBJECTIVE" NlmCategory="OBJECTIVE">In 2010, the World Health Organization (WHO) published revised dosage recommendations for the treatment of tuberculosis (TB) in children. The aim of the survey was to assess whether countries adopt these new dosage recommendations, as well as to identify challenges in the management and treatment of childhood TB. In addition, countries were asked to provide 2010 surveillance data on childhood TB.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">A survey questionnaire was developed and broadly disseminated to National Tuberculosis Programmes or people with close links to them.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Among the 34 countries that responded to the survey, the proportion of total national TB caseload reported in children in 2010 ranged from 0.67% to 23.6%. The data on new cases reported to this survey varied from data provided to the WHO global TB database. Most countries had childhood TB guidelines in place, and half had adopted the new dosage recommendations. Countries reported a number of challenges related to the implementation of the new recommendations and general management of childhood TB.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Despite the adoption of the new dosage recommendations, their implementation is complicated by the lack of appropriate fixed-dose combinations. In addition, accurate and consistent estimates of the global burden of childhood TB remained a major challenge. Technical assistance and support to countries is needed to improve childhood TB activities.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Detjen</LastName><ForeName>A K</ForeName><Initials>AK</Initials><AffiliationInfo><Affiliation>The International Union Against Tuberculosis and Lung Disease, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Macé</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>The International Union Against Tuberculosis and Lung Disease, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perrin</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>The International Union Against Tuberculosis and Lung Disease, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Graham</LastName><ForeName>S M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>The International Union Against Tuberculosis and Lung Disease, Paris, France ; Centre for International Child Health, University of Melbourne Department of Paediatrics and Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grzemska</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Stop TB Partnership, World Health Organization, Geneva, Switzerland.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>France</Country><MedlineTA>Public Health Action</MedlineTA><NlmUniqueID>101624961</NlmUniqueID><ISSNLinking>2220-8372</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Pediatr Rep. 2011 Jun 16;3(2):e16</RefSource><PMID Version="1">21772953</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Med. 2011 Oct;8(10):e1001105</RefSource><PMID Version="1">22022234</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Int J Tuberc Lung Dis. 2009 Mar;13(3):277-8</RefSource><PMID Version="1">19275783</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Antimicrob Agents Chemother. 2011 Dec;55(12):5560-7</RefSource><PMID Version="1">21968358</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Int J Tuberc Lung Dis. 2002 May;6(5):424-31</RefSource><PMID Version="1">12019918</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Dis Child. 2005 Jun;90(6):614-8</RefSource><PMID Version="1">15908628</PMID></CommentsCorrections></CommentsCorrectionsList><OtherID Source="NLM">PMC4463065</OtherID><OtherAbstract Type="Publisher" Language="fre"><AbstractText Label="CONTEXTE ET OBJECTIF">En 2010, l’Organisation Mondiale de la Santé (OMS) a publié des recommandations concernant la révision du dosage pour le traitement de la tuberculose (TB) infantile. Le but de cette enquête a été d’évaluer dans quelle mesure les pays ont adopté ces nouvelles recommandations concernant le nouveau dosage des médicaments et identifié les défis dans la prise en charge et le traitement de la TB infantile. En outre, on a demandé aux pays de fournir les données de surveillance de la TB infantile en 2010.</AbstractText><AbstractText Label="SCHÉMA">Un questionnaire d’enquête a été élaboré et disséminé largement aux Programmes Nationaux de Tuberculose (PNT) et aux personnes très proches des PNT.</AbstractText><AbstractText Label="RÉSULTATS">Parmi les 34 pays qui ont répondu à l’enquête, la proportion du fardeau total national des cas de TB rapportée en 2010 chez les enfants s’est étalée entre 0,67% à 23,6%. Les données concernant les nouveaux cas relatés dans cette enquête ont été différentes de celles fournies à la base mondiale de données de la TB de l’OMS. La plupart des pays disposaient de recommandations pour la TB infantile, et la moitié avaient adopté les recommandations concernant le nouveau dosage. Des pays ont signalé un certain nombre de défis en relation avec la mise en œuvre des nouvelles recommandations et la prise en charge générale de la TB infantile.</AbstractText><AbstractText Label="CONCLUSIONS">Malgré l’adoption des recommandations concernant le nouveau dosage, leur mise en œuvre est compliquée par le manque de combinaisons à dose fixe appropriée. De plus, des estimations exactes et cohérentes du fardeau mondial de la TB infantile restent un défi important. Une aide et un soutien techniques aux pays sont nécessaires afin d’améliorer les activités en matière de TB infantile.</AbstractText></OtherAbstract><OtherAbstract Type="Publisher" Language="spa"><AbstractText Label="MARCO DE REFERENCIA Y OBJETIVO">En el 2010, la Organización Mundial de la Salud (OMS) publicó una revisión de las pautas posológicas recomendadas en el tratamiento de la tuberculosis (TB) en los niños. El objetivo del presente estudio fue evaluar el grado de adopción de estas nuevas recomendaciones por parte de los países y determinar los obstáculos que se presentan en el manejo y el tratamiento de este tipo de TB. Asimismo, se solicitó a los países que suministraran los datos de vigilancia de la TB de los niños en el 2010.</AbstractText><AbstractText Label="MÉTODO">Se elaboró el cuestionario de la encuesta y se difundió ampliamente a los Programas Nacionales de control de la Tuberculosis o a las personas que sostienen un vínculo estrecho con estos programas.</AbstractText><AbstractText Label="RESULTADOS">Treinta y cuatro países respondieron a la encuesta. La proporción de la carga de morbilidad total por TB que correspondió a los niños en el 2010 osciló entre 0,67% y 23,6%. Los datos sobre los casos nuevos notificados en esta encuesta difirieron de los datos su-ministrados a la base mundial de datos sobre la TB de la OMS. La mayoría de los países cuentan localmente con directrices en materia de TB de los niños y la mitad de ellos han adoptado las nuevas pautas posológicas recomendadas. Los países notificaron una serie de obstáculos relacionados con la puesta en práctica de las nuevas recomendaciones y con el manejo general de la TB de los niños.</AbstractText><AbstractText Label="CONCLUSIÓN">Pese a la adopción de las recomendaciones sobre las nuevas posologías, su puesta en práctica se dificulta debido a la falta de combinaciones de dosis fijas adecuadas. Además, lograr un cálculo preciso y sistemático de la carga de morbilidad mundial por TB en los niños constituye aun un obstáculo importante. Los países precisan asistencia técnica y apoyo con el fin de mejorar las actividades relacionadas con la TB en la infancia.</AbstractText></OtherAbstract><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">anti-tuberculosis medicines</Keyword><Keyword MajorTopicYN="N">childhood TB</Keyword><Keyword MajorTopicYN="N">disease burden</Keyword><Keyword MajorTopicYN="N">guidelines</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>08</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2012</Year><Month>10</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>9</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>12</Month><Day>21</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>12</Month><Day>21</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26392970</ArticleId><ArticleId IdType="doi">10.5588/pha.12.0052</ArticleId><ArticleId IdType="pmc">PMC4463065</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>France</li><li>Suisse</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Detjen, A K" sort="Detjen, A K" uniqKey="Detjen A" first="A K" last="Detjen">A K Detjen</name></region><name sortKey="Mace, C" sort="Mace, C" uniqKey="Mace C" first="C" last="Macé">C. Macé</name><name sortKey="Perrin, C" sort="Perrin, C" uniqKey="Perrin C" first="C" last="Perrin">C. Perrin</name></country><country name="Australie"><noRegion><name sortKey="Graham, S M" sort="Graham, S M" uniqKey="Graham S" first="S M" last="Graham">S M Graham</name></noRegion></country><country name="Suisse"><noRegion><name sortKey="Grzemska, M" sort="Grzemska, M" uniqKey="Grzemska M" first="M" last="Grzemska">M. Grzemska</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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