Harmonization of measurement results of the alcohol biomarker carbohydrate-deficient transferrin by use of the toolbox of technical procedures of the International Consortium for Harmonization of Clinical Laboratory Results.
Identifieur interne : 003511 ( PubMed/Checkpoint ); précédent : 003510; suivant : 003512Harmonization of measurement results of the alcohol biomarker carbohydrate-deficient transferrin by use of the toolbox of technical procedures of the International Consortium for Harmonization of Clinical Laboratory Results.
Auteurs : Cas Weykamp [Pays-Bas] ; Jos Wielders [Pays-Bas] ; Anders Helander [Suède] ; Raymond F. Anton [États-Unis] ; Vincenza Bianchi [Italie] ; Jan-Olof Jeppsson [Suède] ; Carla Siebelder [Pays-Bas] ; John B. Whitfield [Australie] ; François Schellenberg [France]Source :
- Clinical chemistry [ 1530-8561 ] ; 2014.
Descripteurs français
- KwdFr :
- Chromatographie en phase liquide à haute performance, Consommation d'alcool (sang), Dosage immunologique, Humains, Marqueurs biologiques (sang), Normes de référence, Néphélométrie et turbidimétrie, Transferrine (analogues et dérivés), Transferrine (analyse), Transferrine (normes), Valeurs de référence, Électrophorèse capillaire.
- MESH :
- analogues et dérivés : Transferrine.
- analyse : Transferrine.
- normes : Transferrine.
- sang : Consommation d'alcool, Marqueurs biologiques.
- Chromatographie en phase liquide à haute performance, Dosage immunologique, Humains, Normes de référence, Néphélométrie et turbidimétrie, Valeurs de référence, Électrophorèse capillaire.
English descriptors
- KwdEn :
- MESH :
- chemical , analogs & derivatives : Transferrin.
- chemical , analysis : Transferrin.
- chemical , blood : Biomarkers.
- blood : Alcohol Drinking.
- chemical , standards : Transferrin.
- Chromatography, High Pressure Liquid, Electrophoresis, Capillary, Humans, Immunoassay, Nephelometry and Turbidimetry, Reference Standards, Reference Values.
Abstract
The need for equivalent results of routine measurement procedures for the alcohol biomarker carbohydrate-deficient transferrin (CDT) has been recognized by the IFCC. This article describes a project to harmonize CDT as conducted by an IFCC working group initiated for this purpose.
DOI: 10.1373/clinchem.2014.221531
PubMed: 24691685
Affiliations:
- Australie, France, Italie, Pays-Bas, Suède, États-Unis
- Caroline du Sud, Centre-Val de Loire, Région Centre, Svealand
- Stockholm, Tours
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:24691685Le document en format XML
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<term>Biomarkers (blood)</term>
<term>Chromatography, High Pressure Liquid</term>
<term>Electrophoresis, Capillary</term>
<term>Humans</term>
<term>Immunoassay</term>
<term>Nephelometry and Turbidimetry</term>
<term>Reference Standards</term>
<term>Reference Values</term>
<term>Transferrin (analogs & derivatives)</term>
<term>Transferrin (analysis)</term>
<term>Transferrin (standards)</term>
</keywords>
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<term>Consommation d'alcool (sang)</term>
<term>Dosage immunologique</term>
<term>Humains</term>
<term>Marqueurs biologiques (sang)</term>
<term>Normes de référence</term>
<term>Néphélométrie et turbidimétrie</term>
<term>Transferrine (analogues et dérivés)</term>
<term>Transferrine (analyse)</term>
<term>Transferrine (normes)</term>
<term>Valeurs de référence</term>
<term>Électrophorèse capillaire</term>
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<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Alcohol Drinking</term>
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<keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Transferrine</term>
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<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Consommation d'alcool</term>
<term>Marqueurs biologiques</term>
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<term>Electrophoresis, Capillary</term>
<term>Humans</term>
<term>Immunoassay</term>
<term>Nephelometry and Turbidimetry</term>
<term>Reference Standards</term>
<term>Reference Values</term>
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<term>Normes de référence</term>
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<front><div type="abstract" xml:lang="en">The need for equivalent results of routine measurement procedures for the alcohol biomarker carbohydrate-deficient transferrin (CDT) has been recognized by the IFCC. This article describes a project to harmonize CDT as conducted by an IFCC working group initiated for this purpose.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24691685</PMID>
<DateCreated><Year>2014</Year>
<Month>06</Month>
<Day>28</Day>
</DateCreated>
<DateCompleted><Year>2014</Year>
<Month>08</Month>
<Day>14</Day>
</DateCompleted>
<DateRevised><Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1530-8561</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>60</Volume>
<Issue>7</Issue>
<PubDate><Year>2014</Year>
<Month>Jul</Month>
</PubDate>
</JournalIssue>
<Title>Clinical chemistry</Title>
<ISOAbbreviation>Clin. Chem.</ISOAbbreviation>
</Journal>
<ArticleTitle>Harmonization of measurement results of the alcohol biomarker carbohydrate-deficient transferrin by use of the toolbox of technical procedures of the International Consortium for Harmonization of Clinical Laboratory Results.</ArticleTitle>
<Pagination><MedlinePgn>945-53</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1373/clinchem.2014.221531</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The need for equivalent results of routine measurement procedures for the alcohol biomarker carbohydrate-deficient transferrin (CDT) has been recognized by the IFCC. This article describes a project to harmonize CDT as conducted by an IFCC working group initiated for this purpose.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We used procedures for achieving harmonization as developed by the Consortium for Harmonization of Clinical Laboratory Results to assess the suitability of a candidate reference measurement procedure (cRMP), candidate reference materials (cRMs), and the success of efforts to achieve harmonization.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">CDT measurement procedures in routine use showed good reproducibility (CV 1.1%-2.8%) and linearity (r > 0.990) with variable slopes (0.766-1.065) and intercepts (-0.34 to 0.92) compared to the cRMP. Heterogeneity after simulated harmonization was 4.7%. cRMs of frozen human native sera demonstrated commutability and 3-year stability for routine measurement procedures. The cRMP provided reproducible value assignment to cRMs with an expanded uncertainty (k = 2) of 0.03% at the 1.2% CDT level and 0.06% at the 4.4% CDT level. Harmonization efforts reduced the intermeasurement CV from 8.8% to 3.4%, allowed 99% recovery of the values assigned with the cRMP, and demonstrated 99% of results within the desirable allowable total error. Harmonization was less successful in samples with low CDT and high trisialotransferrin concentrations.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Harmonization of CDT is possible with frozen human native sera as cRMs with values assigned by use of the cRMP. We propose the cRMP as a candidate international conventional reference measurement procedure and cRMs as candidate international calibrators.</AbstractText>
<CopyrightInformation>© 2014 The American Association for Clinical Chemistry.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Weykamp</LastName>
<ForeName>Cas</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Chemistry, Queen Beatrix Hospital, Winterswijk, the Netherlands; c.w.weykamp@skbwinterswijk.nl.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wielders</LastName>
<ForeName>Jos</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Chemistry, Meander Medical Center, Amersfoort, the Netherlands;</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Helander</LastName>
<ForeName>Anders</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Laboratory Medicine, Karolinska Institutet, and Karolinska University Laboratory, Clinical Chemistry, Stockholm, Sweden;</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Anton</LastName>
<ForeName>Raymond F</ForeName>
<Initials>RF</Initials>
<AffiliationInfo><Affiliation>The Center for Drug and Alcohol Programs, Medical University of South Carolina, Charleston, SC;</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bianchi</LastName>
<ForeName>Vincenza</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Toxicology Reference Laboratory, SS. Antonio e Biagio Hospital, Alessandria, Italy;</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jeppsson</LastName>
<ForeName>Jan-Olof</ForeName>
<Initials>JO</Initials>
<AffiliationInfo><Affiliation>Department of Laboratory Medicine, Malmö University Hospital, Malmö, Sweden;</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Siebelder</LastName>
<ForeName>Carla</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Chemistry, Queen Beatrix Hospital, Winterswijk, the Netherlands;</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Whitfield</LastName>
<ForeName>John B</ForeName>
<Initials>JB</Initials>
<AffiliationInfo><Affiliation>Queensland Institute of Medical Research, Brisbane, Australia;</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schellenberg</LastName>
<ForeName>François</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Laboratoire de Biochimie, Hôpital Trousseau, Tours, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>IFCC Working Group on Standardization of Carbohydrate-Deficient Transferrin</CollectiveName>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>K05 AA 17435</GrantID>
<Acronym>AA</Acronym>
<Agency>NIAAA NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>04</Month>
<Day>01</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Clin Chem</MedlineTA>
<NlmUniqueID>9421549</NlmUniqueID>
<ISSNLinking>0009-9147</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014168">Transferrin</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C056759">carbohydrate-deficient transferrin</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Clin Chem. 2014 Jul;60(7):911-3</RefSource>
<PMID Version="1">24799526</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="CommentIn"><RefSource>Clin Chem. 2014 Oct;60(10):1347-8</RefSource>
<PMID Version="1">25125347</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000428" MajorTopicYN="N">Alcohol Drinking</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015415" MajorTopicYN="N">Biomarkers</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002851" MajorTopicYN="N">Chromatography, High Pressure Liquid</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019075" MajorTopicYN="N">Electrophoresis, Capillary</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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