International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation.
Identifieur interne : 003452 ( PubMed/Checkpoint ); précédent : 003451; suivant : 003453International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation.
Auteurs : Antonio Palumbo [États-Unis] ; S Vincent Rajkumar ; Jesus F. San Miguel ; Alessandra Larocca ; Ruben Niesvizky ; Gareth Morgan ; Ola Landgren ; Roman Hajek ; Hermann Einsele ; Kenneth C. Anderson ; Meletios A. Dimopoulos ; Paul G. Richardson ; Michele Cavo ; Andrew Spencer ; A Keith Stewart ; Kazuyuki Shimizu ; Sagar Lonial ; Pieter Sonneveld ; Brian G M. Durie ; Philippe Moreau ; Robert Z. OrlowskiSource :
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology [ 1527-7755 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- diagnosis : Multiple Myeloma.
- therapy : Multiple Myeloma.
- Hematopoietic Stem Cell Transplantation, Humans, Palliative Care, Prognosis.
Abstract
To provide an update on recent advances in the management of patients with multiple myeloma who are not eligible for autologous stem-cell transplantation.
DOI: 10.1200/JCO.2013.48.7934
PubMed: 24419113
Affiliations:
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pubmed:24419113Le document en format XML
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San Miguel, University Hospital of Salamanca, Salamanca, Spain; Ruben Niesvizky, Weill Cornell Medical College, New York, NY; Gareth Morgan, Royal Marsden Hospital, London, United Kingdom; Ola Landgren, National Cancer Institute, Bethesda, MD; Roman Hajek, University of Ostrava School of Medicine and University Hospital Ostrava, Ostrava, Czech Republic; Hermann Einsele, University of Wurzburg, Wurzburg, Germany; Kenneth C. Anderson and Paul G. Richardson, Dana-Farber Cancer Institute, Boston, MA; Meletios A. Dimopoulos, University of Athens School of Medicine, Athens, Greece; Andrew Spencer, Alfred Hospital, Melbourne, Victoria, Australia; A. Keith Stewart, Mayo Clinic, Scottsdale, AZ; Kazuyuki Shimizu, Aichi Gakuin Hospital, Nagoya, Japan; Sagar Lonial, Emory University, Atlanta, GA; Pieter Sonneveld, Erasmus Medical Centre, Rotterdam, the Netherlands; Brian G.M. 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Vincent Rajkumar, Mayo Clinic, Rochester, MN; Jesus F. San Miguel, University Hospital of Salamanca, Salamanca, Spain; Ruben Niesvizky, Weill Cornell Medical College, New York, NY; Gareth Morgan, Royal Marsden Hospital, London, United Kingdom; Ola Landgren, National Cancer Institute, Bethesda, MD; Roman Hajek, University of Ostrava School of Medicine and University Hospital Ostrava, Ostrava, Czech Republic; Hermann Einsele, University of Wurzburg, Wurzburg, Germany; Kenneth C. Anderson and Paul G. Richardson, Dana-Farber Cancer Institute, Boston, MA; Meletios A. Dimopoulos, University of Athens School of Medicine, Athens, Greece; Andrew Spencer, Alfred Hospital, Melbourne, Victoria, Australia; A. Keith Stewart, Mayo Clinic, Scottsdale, AZ; Kazuyuki Shimizu, Aichi Gakuin Hospital, Nagoya, Japan; Sagar Lonial, Emory University, Atlanta, GA; Pieter Sonneveld, Erasmus Medical Centre, Rotterdam, the Netherlands; Brian G.M. Durie, Cedars-Sinai Comprehensive Cancer Center, Los Angeles, CA; Philippe Moreau, University Hospital, Nantes, France; and Robert Z. Orlowski, MD Anderson Cancer Center, Houston, TX.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Antonio Palumbo and Alessandra Larocca, University of Torino, Torino; Michele Cavo, Seràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy; S. Vincent Rajkumar, Mayo Clinic, Rochester, MN; Jesus F. San Miguel, University Hospital of Salamanca, Salamanca, Spain; Ruben Niesvizky, Weill Cornell Medical College, New York, NY; Gareth Morgan, Royal Marsden Hospital, London, United Kingdom; Ola Landgren, National Cancer Institute, Bethesda, MD; Roman Hajek, University of Ostrava School of Medicine and University Hospital Ostrava, Ostrava, Czech Republic; Hermann Einsele, University of Wurzburg, Wurzburg, Germany; Kenneth C. Anderson and Paul G. Richardson, Dana-Farber Cancer Institute, Boston, MA; Meletios A. Dimopoulos, University of Athens School of Medicine, Athens, Greece; Andrew Spencer, Alfred Hospital, Melbourne, Victoria, Australia; A. Keith Stewart, Mayo Clinic, Scottsdale, AZ; Kazuyuki Shimizu, Aichi Gakuin Hospital, Nagoya, Japan; Sagar Lonial, Emory University, Atlanta, GA; Pieter Sonneveld, Erasmus Medical Centre, Rotterdam, the Netherlands; Brian G.M. Durie, Cedars-Sinai Comprehensive Cancer Center, Los Angeles, CA; Philippe Moreau, University Hospital, Nantes, France; and Robert Z. Orlowski, MD Anderson Cancer Center, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Rajkumar, S Vincent" sort="Rajkumar, S Vincent" uniqKey="Rajkumar S" first="S Vincent" last="Rajkumar">S Vincent Rajkumar</name></author><author><name sortKey="San Miguel, Jesus F" sort="San Miguel, Jesus F" uniqKey="San Miguel J" first="Jesus F" last="San Miguel">Jesus F. San Miguel</name></author><author><name sortKey="Larocca, Alessandra" sort="Larocca, Alessandra" uniqKey="Larocca A" first="Alessandra" last="Larocca">Alessandra Larocca</name></author><author><name sortKey="Niesvizky, Ruben" sort="Niesvizky, Ruben" uniqKey="Niesvizky R" first="Ruben" last="Niesvizky">Ruben Niesvizky</name></author><author><name sortKey="Morgan, Gareth" sort="Morgan, Gareth" uniqKey="Morgan G" first="Gareth" last="Morgan">Gareth Morgan</name></author><author><name sortKey="Landgren, Ola" sort="Landgren, Ola" uniqKey="Landgren O" first="Ola" last="Landgren">Ola Landgren</name></author><author><name sortKey="Hajek, Roman" sort="Hajek, Roman" uniqKey="Hajek R" first="Roman" last="Hajek">Roman Hajek</name></author><author><name sortKey="Einsele, Hermann" sort="Einsele, Hermann" uniqKey="Einsele H" first="Hermann" last="Einsele">Hermann Einsele</name></author><author><name sortKey="Anderson, Kenneth C" sort="Anderson, Kenneth C" uniqKey="Anderson K" first="Kenneth C" last="Anderson">Kenneth C. Anderson</name></author><author><name sortKey="Dimopoulos, Meletios A" sort="Dimopoulos, Meletios A" uniqKey="Dimopoulos M" first="Meletios A" last="Dimopoulos">Meletios A. Dimopoulos</name></author><author><name sortKey="Richardson, Paul G" sort="Richardson, Paul G" uniqKey="Richardson P" first="Paul G" last="Richardson">Paul G. Richardson</name></author><author><name sortKey="Cavo, Michele" sort="Cavo, Michele" uniqKey="Cavo M" first="Michele" last="Cavo">Michele Cavo</name></author><author><name sortKey="Spencer, Andrew" sort="Spencer, Andrew" uniqKey="Spencer A" first="Andrew" last="Spencer">Andrew Spencer</name></author><author><name sortKey="Stewart, A Keith" sort="Stewart, A Keith" uniqKey="Stewart A" first="A Keith" last="Stewart">A Keith Stewart</name></author><author><name sortKey="Shimizu, Kazuyuki" sort="Shimizu, Kazuyuki" uniqKey="Shimizu K" first="Kazuyuki" last="Shimizu">Kazuyuki Shimizu</name></author><author><name sortKey="Lonial, Sagar" sort="Lonial, Sagar" uniqKey="Lonial S" first="Sagar" last="Lonial">Sagar Lonial</name></author><author><name sortKey="Sonneveld, Pieter" sort="Sonneveld, Pieter" uniqKey="Sonneveld P" first="Pieter" last="Sonneveld">Pieter Sonneveld</name></author><author><name sortKey="Durie, Brian G M" sort="Durie, Brian G M" uniqKey="Durie B" first="Brian G M" last="Durie">Brian G M. Durie</name></author><author><name sortKey="Moreau, Philippe" sort="Moreau, Philippe" uniqKey="Moreau P" first="Philippe" last="Moreau">Philippe Moreau</name></author><author><name sortKey="Orlowski, Robert Z" sort="Orlowski, Robert Z" uniqKey="Orlowski R" first="Robert Z" last="Orlowski">Robert Z. Orlowski</name></author></analytic><series><title level="j">Journal of clinical oncology : official journal of the American Society of Clinical Oncology</title><idno type="eISSN">1527-7755</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Hematopoietic Stem Cell Transplantation</term><term>Humans</term><term>Multiple Myeloma (diagnosis)</term><term>Multiple Myeloma (therapy)</term><term>Palliative Care</term><term>Prognosis</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Humains</term><term>Myélome multiple ()</term><term>Myélome multiple (diagnostic)</term><term>Pronostic</term><term>Soins palliatifs</term><term>Transplantation de cellules souches hématopoïétiques</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Multiple Myeloma</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Myélome multiple</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Multiple Myeloma</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Hematopoietic Stem Cell Transplantation</term><term>Humans</term><term>Palliative Care</term><term>Prognosis</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Myélome multiple</term><term>Pronostic</term><term>Soins palliatifs</term><term>Transplantation de cellules souches hématopoïétiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To provide an update on recent advances in the management of patients with multiple myeloma who are not eligible for autologous stem-cell transplantation.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24419113</PMID><DateCreated><Year>2014</Year><Month>02</Month><Day>17</Day></DateCreated><DateCompleted><Year>2014</Year><Month>04</Month><Day>14</Day></DateCompleted><DateRevised><Year>2016</Year><Month>10</Month><Day>25</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1527-7755</ISSN><JournalIssue CitedMedium="Internet"><Volume>32</Volume><Issue>6</Issue><PubDate><Year>2014</Year><Month>Feb</Month><Day>20</Day></PubDate></JournalIssue><Title>Journal of clinical oncology : official journal of the American Society of Clinical Oncology</Title><ISOAbbreviation>J. Clin. Oncol.</ISOAbbreviation></Journal><ArticleTitle>International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation.</ArticleTitle><Pagination><MedlinePgn>587-600</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1200/JCO.2013.48.7934</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To provide an update on recent advances in the management of patients with multiple myeloma who are not eligible for autologous stem-cell transplantation.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A comprehensive review of the literature on diagnostic criteria is provided, and treatment options and management of adverse events are summarized.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Patients with symptomatic disease and organ damage (ie, hypercalcemia, renal failure, anemia, or bone lesions) require immediate treatment. The International Staging System and chromosomal abnormalities identify high- and standard-risk patients. Proteasome inhibitors, immunomodulatory drugs, corticosteroids, and alkylating agents are the most active agents. The presence of concomitant diseases, frailty, or disability should be assessed and, if present, treated with reduced-dose approaches. Bone disease, renal damage, hematologic toxicities, infections, thromboembolism, and peripheral neuropathy are the most frequent disabling events requiring prompt and active supportive care.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">These recommendations will help clinicians ensure the most appropriate care for patients with myeloma in everyday clinical practice.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Palumbo</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Antonio Palumbo and Alessandra Larocca, University of Torino, Torino; Michele Cavo, Seràgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy; S. Vincent Rajkumar, Mayo Clinic, Rochester, MN; Jesus F. San Miguel, University Hospital of Salamanca, Salamanca, Spain; Ruben Niesvizky, Weill Cornell Medical College, New York, NY; Gareth Morgan, Royal Marsden Hospital, London, United Kingdom; Ola Landgren, National Cancer Institute, Bethesda, MD; Roman Hajek, University of Ostrava School of Medicine and University Hospital Ostrava, Ostrava, Czech Republic; Hermann Einsele, University of Wurzburg, Wurzburg, Germany; Kenneth C. Anderson and Paul G. Richardson, Dana-Farber Cancer Institute, Boston, MA; Meletios A. Dimopoulos, University of Athens School of Medicine, Athens, Greece; Andrew Spencer, Alfred Hospital, Melbourne, Victoria, Australia; A. Keith Stewart, Mayo Clinic, Scottsdale, AZ; Kazuyuki Shimizu, Aichi Gakuin Hospital, Nagoya, Japan; Sagar Lonial, Emory University, Atlanta, GA; Pieter Sonneveld, Erasmus Medical Centre, Rotterdam, the Netherlands; Brian G.M. Durie, Cedars-Sinai Comprehensive Cancer Center, Los Angeles, CA; Philippe Moreau, University Hospital, Nantes, France; and Robert Z. Orlowski, MD Anderson Cancer Center, Houston, TX.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rajkumar</LastName><ForeName>S Vincent</ForeName><Initials>SV</Initials></Author><Author ValidYN="Y"><LastName>San Miguel</LastName><ForeName>Jesus F</ForeName><Initials>JF</Initials></Author><Author ValidYN="Y"><LastName>Larocca</LastName><ForeName>Alessandra</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Niesvizky</LastName><ForeName>Ruben</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Morgan</LastName><ForeName>Gareth</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Landgren</LastName><ForeName>Ola</ForeName><Initials>O</Initials></Author><Author ValidYN="Y"><LastName>Hajek</LastName><ForeName>Roman</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Einsele</LastName><ForeName>Hermann</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Anderson</LastName><ForeName>Kenneth C</ForeName><Initials>KC</Initials></Author><Author ValidYN="Y"><LastName>Dimopoulos</LastName><ForeName>Meletios A</ForeName><Initials>MA</Initials></Author><Author ValidYN="Y"><LastName>Richardson</LastName><ForeName>Paul G</ForeName><Initials>PG</Initials></Author><Author ValidYN="Y"><LastName>Cavo</LastName><ForeName>Michele</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Spencer</LastName><ForeName>Andrew</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Stewart</LastName><ForeName>A Keith</ForeName><Initials>AK</Initials></Author><Author ValidYN="Y"><LastName>Shimizu</LastName><ForeName>Kazuyuki</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Lonial</LastName><ForeName>Sagar</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Sonneveld</LastName><ForeName>Pieter</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Durie</LastName><ForeName>Brian G M</ForeName><Initials>BG</Initials></Author><Author ValidYN="Y"><LastName>Moreau</LastName><ForeName>Philippe</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Orlowski</LastName><ForeName>Robert Z</ForeName><Initials>RZ</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>P50 CA142509</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U10 CA032102</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>01</Month><Day>13</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Clin 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Source="NLM">PMC3918540</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>1</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>1</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>4</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24419113</ArticleId><ArticleId IdType="pii">JCO.2013.48.7934</ArticleId><ArticleId IdType="doi">10.1200/JCO.2013.48.7934</ArticleId><ArticleId IdType="pmc">PMC3918540</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Texas</li></region></list><tree><noCountry><name sortKey="Anderson, Kenneth C" sort="Anderson, Kenneth C" uniqKey="Anderson K" first="Kenneth C" last="Anderson">Kenneth C. Anderson</name><name sortKey="Cavo, Michele" sort="Cavo, Michele" uniqKey="Cavo M" first="Michele" last="Cavo">Michele Cavo</name><name sortKey="Dimopoulos, Meletios A" sort="Dimopoulos, Meletios A" uniqKey="Dimopoulos M" first="Meletios A" last="Dimopoulos">Meletios A. Dimopoulos</name><name sortKey="Durie, Brian G M" sort="Durie, Brian G M" uniqKey="Durie B" first="Brian G M" last="Durie">Brian G M. Durie</name><name sortKey="Einsele, Hermann" sort="Einsele, Hermann" uniqKey="Einsele H" first="Hermann" last="Einsele">Hermann Einsele</name><name sortKey="Hajek, Roman" sort="Hajek, Roman" uniqKey="Hajek R" first="Roman" last="Hajek">Roman Hajek</name><name sortKey="Landgren, Ola" sort="Landgren, Ola" uniqKey="Landgren O" first="Ola" last="Landgren">Ola Landgren</name><name sortKey="Larocca, Alessandra" sort="Larocca, Alessandra" uniqKey="Larocca A" first="Alessandra" last="Larocca">Alessandra Larocca</name><name sortKey="Lonial, Sagar" sort="Lonial, Sagar" uniqKey="Lonial S" first="Sagar" last="Lonial">Sagar Lonial</name><name sortKey="Moreau, Philippe" sort="Moreau, Philippe" uniqKey="Moreau P" first="Philippe" last="Moreau">Philippe Moreau</name><name sortKey="Morgan, Gareth" sort="Morgan, Gareth" uniqKey="Morgan G" first="Gareth" last="Morgan">Gareth Morgan</name><name sortKey="Niesvizky, Ruben" sort="Niesvizky, Ruben" uniqKey="Niesvizky R" first="Ruben" last="Niesvizky">Ruben Niesvizky</name><name sortKey="Orlowski, Robert Z" sort="Orlowski, Robert Z" uniqKey="Orlowski R" first="Robert Z" last="Orlowski">Robert Z. Orlowski</name><name sortKey="Rajkumar, S Vincent" sort="Rajkumar, S Vincent" uniqKey="Rajkumar S" first="S Vincent" last="Rajkumar">S Vincent Rajkumar</name><name sortKey="Richardson, Paul G" sort="Richardson, Paul G" uniqKey="Richardson P" first="Paul G" last="Richardson">Paul G. Richardson</name><name sortKey="San Miguel, Jesus F" sort="San Miguel, Jesus F" uniqKey="San Miguel J" first="Jesus F" last="San Miguel">Jesus F. San Miguel</name><name sortKey="Shimizu, Kazuyuki" sort="Shimizu, Kazuyuki" uniqKey="Shimizu K" first="Kazuyuki" last="Shimizu">Kazuyuki Shimizu</name><name sortKey="Sonneveld, Pieter" sort="Sonneveld, Pieter" uniqKey="Sonneveld P" first="Pieter" last="Sonneveld">Pieter Sonneveld</name><name sortKey="Spencer, Andrew" sort="Spencer, Andrew" uniqKey="Spencer A" first="Andrew" last="Spencer">Andrew Spencer</name><name sortKey="Stewart, A Keith" sort="Stewart, A Keith" uniqKey="Stewart A" first="A Keith" last="Stewart">A Keith Stewart</name></noCountry><country name="États-Unis"><region name="Texas"><name sortKey="Palumbo, Antonio" sort="Palumbo, Antonio" uniqKey="Palumbo A" first="Antonio" last="Palumbo">Antonio Palumbo</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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