Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial.
Identifieur interne : 001F92 ( PubMed/Checkpoint ); précédent : 001F91; suivant : 001F93Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial.
Auteurs : A. Boswood [Royaume-Uni] ; J. H Ggström ; S G Gordon [États-Unis] ; G. Wess [Allemagne] ; R L Stepien [États-Unis] ; M A Oyama [États-Unis] ; B W Keene [États-Unis] ; J. Bonagura [États-Unis] ; K A Macdonald [États-Unis] ; M. Patteson [Royaume-Uni] ; S. Smith [Royaume-Uni] ; P R Fox [États-Unis] ; K. Sanderson [États-Unis] ; R. Woolley [Australie] ; V. Szatmári [Pays-Bas] ; P. Menaut [France] ; W M Church [États-Unis] ; M L O'Sullivan [Canada] ; J-P Jaudon [France] ; J-G Kresken [Allemagne] ; J. Rush [États-Unis] ; K A Barrett [États-Unis] ; S L Rosenthal [États-Unis] ; A B Saunders [États-Unis] ; I. Ljungvall ; M. Deinert [Allemagne] ; E. Bomassi [France] ; A H Estrada [États-Unis] ; M J Fernandez Del Palacio [Espagne] ; N S Moise [États-Unis] ; J A Abbott [États-Unis] ; Y. Fujii [Japon] ; A. Spier [États-Unis] ; M W Luethy [États-Unis] ; R A Santilli [Italie] ; M. Uechi [Japon] ; A. Tidholm [Suède] ; P. Watson [Allemagne]Source :
- Journal of veterinary internal medicine [ 1939-1676 ] ; 2016.
Abstract
Pimobendan is effective in treatment of dogs with congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Its effect on dogs before the onset of CHF is unknown.
DOI: 10.1111/jvim.14586
PubMed: 27678080
Affiliations:
- Allemagne, Australie, Canada, Espagne, France, Italie, Japon, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Arizona, Bavière, Californie, Caroline du Nord, Colorado, District de Haute-Bavière, Floride, Illinois, Maryland, Massachusetts, Ohio, Pennsylvanie, Texas, Utrecht (province), Virginie, Wisconsin, État de New York, Île-de-France
- Meaux, Munich, Utrecht
- Université Louis-et-Maximilien de Munich, Université d'Utrecht
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Ljungvall</name><affiliation><nlm:affiliation>Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, SE.</nlm:affiliation><wicri:noCountry code="subField">SE</wicri:noCountry></affiliation></author><author><name sortKey="Deinert, M" sort="Deinert, M" uniqKey="Deinert M" first="M" last="Deinert">M. Deinert</name><affiliation wicri:level="1"><nlm:affiliation>Tierklinik am Sandpfad, Wiesloch, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Tierklinik am Sandpfad, Wiesloch</wicri:regionArea><wicri:noRegion>Wiesloch</wicri:noRegion><wicri:noRegion>Wiesloch</wicri:noRegion><wicri:noRegion>Wiesloch</wicri:noRegion></affiliation></author><author><name sortKey="Bomassi, E" sort="Bomassi, E" uniqKey="Bomassi E" first="E" last="Bomassi">E. Bomassi</name><affiliation wicri:level="3"><nlm:affiliation>Cardiology, Centre Hospitalier Vétérinaire des Cordeliers, Meaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Cardiology, Centre Hospitalier Vétérinaire des Cordeliers, Meaux</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Meaux</settlement></placeName></affiliation></author><author><name sortKey="Estrada, A H" sort="Estrada, A H" uniqKey="Estrada A" first="A H" last="Estrada">A H Estrada</name><affiliation wicri:level="2"><nlm:affiliation>Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, FL.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville</wicri:cityArea></affiliation></author><author><name sortKey="Fernandez Del Palacio, M J" sort="Fernandez Del Palacio, M J" uniqKey="Fernandez Del Palacio M" first="M J" last="Fernandez Del Palacio">M J Fernandez Del Palacio</name><affiliation wicri:level="1"><nlm:affiliation>Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Murcia, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Murcia</wicri:regionArea><wicri:noRegion>Murcia</wicri:noRegion></affiliation></author><author><name sortKey="Moise, N S" sort="Moise, N S" uniqKey="Moise N" first="N S" last="Moise">N S Moise</name><affiliation wicri:level="2"><nlm:affiliation>Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca</wicri:cityArea></affiliation></author><author><name sortKey="Abbott, J A" sort="Abbott, J A" uniqKey="Abbott J" first="J A" last="Abbott">J A Abbott</name><affiliation wicri:level="2"><nlm:affiliation>Department of Small Animal Clinical Sciences, Virginia Tech, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Virginie</region></placeName><wicri:cityArea>Department of Small Animal Clinical Sciences, Virginia Tech, Virginia-Maryland College of Veterinary Medicine, Blacksburg</wicri:cityArea></affiliation></author><author><name sortKey="Fujii, Y" sort="Fujii, Y" uniqKey="Fujii Y" first="Y" last="Fujii">Y. Fujii</name><affiliation wicri:level="1"><nlm:affiliation>Azabu University, Chuo-ku, Sagamihara, Kanagawa, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Azabu University, Chuo-ku, Sagamihara, Kanagawa</wicri:regionArea><wicri:noRegion>Kanagawa</wicri:noRegion></affiliation></author><author><name sortKey="Spier, A" sort="Spier, A" uniqKey="Spier A" first="A" last="Spier">A. Spier</name><affiliation wicri:level="2"><nlm:affiliation>Blue Pearl Veterinary Partners, Tampa, FL.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Blue Pearl Veterinary Partners, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Luethy, M W" sort="Luethy, M W" uniqKey="Luethy M" first="M W" last="Luethy">M W Luethy</name><affiliation wicri:level="2"><nlm:affiliation>Chicago Veterinary Emergency and Specialty Center, Chicago, IL.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Chicago Veterinary Emergency and Specialty Center, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Santilli, R A" sort="Santilli, R A" uniqKey="Santilli R" first="R A" last="Santilli">R A Santilli</name><affiliation wicri:level="1"><nlm:affiliation>Cardiology, Clinica Veterinaria Malpensa, Viale Marconi, Varese, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Cardiology, Clinica Veterinaria Malpensa, Viale Marconi, Varese</wicri:regionArea><wicri:noRegion>Varese</wicri:noRegion></affiliation></author><author><name sortKey="Uechi, M" sort="Uechi, M" uniqKey="Uechi M" first="M" last="Uechi">M. Uechi</name><affiliation wicri:level="1"><nlm:affiliation>JASMINE Veterinary Cardiovascular Medical Center, Japan Animal Specialty Medical Institute Inc., Yokohama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>JASMINE Veterinary Cardiovascular Medical Center, Japan Animal Specialty Medical Institute Inc., Yokohama</wicri:regionArea><wicri:noRegion>Yokohama</wicri:noRegion></affiliation></author><author><name sortKey="Tidholm, A" sort="Tidholm, A" uniqKey="Tidholm A" first="A" last="Tidholm">A. Tidholm</name><affiliation wicri:level="1"><nlm:affiliation>Djursjukhuset Albano, Danderyd, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Djursjukhuset Albano, Danderyd</wicri:regionArea><wicri:noRegion>Danderyd</wicri:noRegion></affiliation></author><author><name sortKey="Watson, P" sort="Watson, P" uniqKey="Watson P" first="P" last="Watson">P. Watson</name><affiliation wicri:level="1"><nlm:affiliation>Boehringer Ingelheim, Animal Health, Ingelheim am Rhein, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Boehringer Ingelheim, Animal Health, Ingelheim am Rhein</wicri:regionArea><wicri:noRegion>Ingelheim am Rhein</wicri:noRegion><wicri:noRegion>Ingelheim am Rhein</wicri:noRegion><wicri:noRegion>Ingelheim am Rhein</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27678080</idno><idno type="pmid">27678080</idno><idno type="doi">10.1111/jvim.14586</idno><idno type="wicri:Area/PubMed/Corpus">001684</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001684</idno><idno type="wicri:Area/PubMed/Curation">001662</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001662</idno><idno type="wicri:Area/PubMed/Checkpoint">001662</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001662</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial.</title><author><name sortKey="Boswood, A" sort="Boswood, A" uniqKey="Boswood A" first="A" last="Boswood">A. Boswood</name><affiliation wicri:level="1"><nlm:affiliation>Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hatfield, Hertfordshire, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hatfield, Hertfordshire</wicri:regionArea><wicri:noRegion>Hertfordshire</wicri:noRegion></affiliation></author><author><name sortKey="H Ggstrom, J" sort="H Ggstrom, J" uniqKey="H Ggstrom J" first="J" last="H Ggström">J. H Ggström</name><affiliation><nlm:affiliation>Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, SE.</nlm:affiliation><wicri:noCountry code="subField">SE</wicri:noCountry></affiliation></author><author><name sortKey="Gordon, S G" sort="Gordon, S G" uniqKey="Gordon S" first="S G" last="Gordon">S G Gordon</name><affiliation wicri:level="2"><nlm:affiliation>Small Animal Clinical Science, Texas A&M University, College Station, TX.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Small Animal Clinical Science, Texas A&M University, College Station</wicri:cityArea></affiliation></author><author><name sortKey="Wess, G" sort="Wess, G" uniqKey="Wess G" first="G" last="Wess">G. Wess</name><affiliation wicri:level="4"><nlm:affiliation>Clinic of Small Animal Medicine, University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Clinic of Small Animal Medicine, University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Stepien, R L" sort="Stepien, R L" uniqKey="Stepien R" first="R L" last="Stepien">R L Stepien</name><affiliation wicri:level="2"><nlm:affiliation>Medical Sciences, University of Wisconsin Madison School of Veterinary Medicine, Madison, WI.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Wisconsin</region></placeName><wicri:cityArea>Medical Sciences, University of Wisconsin Madison School of Veterinary Medicine, Madison</wicri:cityArea></affiliation></author><author><name sortKey="Oyama, M A" sort="Oyama, M A" uniqKey="Oyama M" first="M A" last="Oyama">M A Oyama</name><affiliation wicri:level="2"><nlm:affiliation>Clinical Studies-Philadelphia, MJR-VHUP-Cardiology, University of Pennsylvania, Philadelphia, PA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Clinical Studies-Philadelphia, MJR-VHUP-Cardiology, University of Pennsylvania, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Keene, B W" sort="Keene, B W" uniqKey="Keene B" first="B W" last="Keene">B W Keene</name><affiliation wicri:level="2"><nlm:affiliation>Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh</wicri:cityArea></affiliation></author><author><name sortKey="Bonagura, J" sort="Bonagura, J" uniqKey="Bonagura J" first="J" last="Bonagura">J. Bonagura</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Veterinary Clinical Sciences, The Ohio State University, Columbus</wicri:cityArea></affiliation></author><author><name sortKey="Macdonald, K A" sort="Macdonald, K A" uniqKey="Macdonald K" first="K A" last="Macdonald">K A Macdonald</name><affiliation wicri:level="2"><nlm:affiliation>Animal Care Center, Rohnert Park, CA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Animal Care Center, Rohnert Park</wicri:cityArea></affiliation></author><author><name sortKey="Patteson, M" sort="Patteson, M" uniqKey="Patteson M" first="M" last="Patteson">M. Patteson</name><affiliation wicri:level="1"><nlm:affiliation>HeartVets @ Vale Referrals, The Animal Hospital, Dursley, Gloucestershire, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>HeartVets @ Vale Referrals, The Animal Hospital, Dursley, Gloucestershire</wicri:regionArea><wicri:noRegion>Gloucestershire</wicri:noRegion></affiliation></author><author><name sortKey="Smith, S" sort="Smith, S" uniqKey="Smith S" first="S" last="Smith">S. Smith</name><affiliation wicri:level="1"><nlm:affiliation>Sarah Smith Cardiology, Derby, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Sarah Smith Cardiology, Derby</wicri:regionArea><wicri:noRegion>Derby</wicri:noRegion></affiliation></author><author><name sortKey="Fox, P R" sort="Fox, P R" uniqKey="Fox P" first="P R" last="Fox">P R Fox</name><affiliation wicri:level="2"><nlm:affiliation>Animal Medical Center, New York, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Animal Medical Center, New York</wicri:cityArea></affiliation></author><author><name sortKey="Sanderson, K" sort="Sanderson, K" uniqKey="Sanderson K" first="K" last="Sanderson">K. Sanderson</name><affiliation wicri:level="2"><nlm:affiliation>Rocky Mountain Veterinary Cardiology, Boulder, CO.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Colorado</region></placeName><wicri:cityArea>Rocky Mountain Veterinary Cardiology, Boulder</wicri:cityArea></affiliation></author><author><name sortKey="Woolley, R" sort="Woolley, R" uniqKey="Woolley R" first="R" last="Woolley">R. Woolley</name><affiliation wicri:level="1"><nlm:affiliation>Cardio Respiratory Pet Referrals Victoria, Mordialloc, Vic, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cardio Respiratory Pet Referrals Victoria, Mordialloc, Vic</wicri:regionArea><wicri:noRegion>Vic</wicri:noRegion></affiliation></author><author><name sortKey="Szatmari, V" sort="Szatmari, V" uniqKey="Szatmari V" first="V" last="Szatmári">V. Szatmári</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Veterinary Medicine, Clinical Sciences of Companion Animals, Utrecht University, Utrecht, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Faculty of Veterinary Medicine, Clinical Sciences of Companion Animals, Utrecht University, Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region><settlement type="city">Utrecht</settlement></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Menaut, P" sort="Menaut, P" uniqKey="Menaut P" first="P" last="Menaut">P. Menaut</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine and Cardiology, Clinique Vétérinaire Aquivet, Eysines, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Internal Medicine and Cardiology, Clinique Vétérinaire Aquivet, Eysines</wicri:regionArea><wicri:noRegion>Eysines</wicri:noRegion><wicri:noRegion>Eysines</wicri:noRegion></affiliation></author><author><name sortKey="Church, W M" sort="Church, W M" uniqKey="Church W" first="W M" last="Church">W M Church</name><affiliation wicri:level="2"><nlm:affiliation>Desert Veterinary Medical Specialists, Phoenix, AZ.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Arizona</region></placeName><wicri:cityArea>Desert Veterinary Medical Specialists, Phoenix</wicri:cityArea></affiliation></author><author><name sortKey="O Sullivan, M L" sort="O Sullivan, M L" uniqKey="O Sullivan M" first="M L" last="O'Sullivan">M L O'Sullivan</name><affiliation wicri:level="1"><nlm:affiliation>Deptartment of Clinical Studies, University of Guelph, Ontario Veterinary College, Guelph, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Deptartment of Clinical Studies, University of Guelph, Ontario Veterinary College, Guelph, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Jaudon, J P" sort="Jaudon, J P" uniqKey="Jaudon J" first="J-P" last="Jaudon">J-P Jaudon</name><affiliation wicri:level="1"><nlm:affiliation>Clinique Veterinaire Des Etangs, Villars Les Dombes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Clinique Veterinaire Des Etangs, Villars Les Dombes</wicri:regionArea><wicri:noRegion>Villars Les Dombes</wicri:noRegion><wicri:noRegion>Villars Les Dombes</wicri:noRegion></affiliation></author><author><name sortKey="Kresken, J G" sort="Kresken, J G" uniqKey="Kresken J" first="J-G" last="Kresken">J-G Kresken</name><affiliation wicri:level="1"><nlm:affiliation>Clinic for Small Animals Kaiserberg, Duisburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Clinic for Small Animals Kaiserberg, Duisburg</wicri:regionArea><wicri:noRegion>Duisburg</wicri:noRegion><wicri:noRegion>Duisburg</wicri:noRegion><wicri:noRegion>Duisburg</wicri:noRegion></affiliation></author><author><name sortKey="Rush, J" sort="Rush, J" uniqKey="Rush J" first="J" last="Rush">J. Rush</name><affiliation wicri:level="2"><nlm:affiliation>Clinical Sciences, Tufts University Cummings School of Veterinary Medicine, North Grafton, MA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Clinical Sciences, Tufts University Cummings School of Veterinary Medicine, North Grafton</wicri:cityArea></affiliation></author><author><name sortKey="Barrett, K A" sort="Barrett, K A" uniqKey="Barrett K" first="K A" last="Barrett">K A Barrett</name><affiliation wicri:level="2"><nlm:affiliation>Cardiology, VCA West Los Angeles, Los Angeles, CA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cardiology, VCA West Los Angeles, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Rosenthal, S L" sort="Rosenthal, S L" uniqKey="Rosenthal S" first="S L" last="Rosenthal">S L Rosenthal</name><affiliation wicri:level="2"><nlm:affiliation>Cardiac Care for Pets, Towson, MD.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Cardiac Care for Pets, Towson</wicri:cityArea></affiliation></author><author><name sortKey="Saunders, A B" sort="Saunders, A B" uniqKey="Saunders A" first="A B" last="Saunders">A B Saunders</name><affiliation wicri:level="2"><nlm:affiliation>Small Animal Clinical Science, Texas A&M University, College Station, TX.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Small Animal Clinical Science, Texas A&M University, College Station</wicri:cityArea></affiliation></author><author><name sortKey="Ljungvall, I" sort="Ljungvall, I" uniqKey="Ljungvall I" first="I" last="Ljungvall">I. Ljungvall</name><affiliation><nlm:affiliation>Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, SE.</nlm:affiliation><wicri:noCountry code="subField">SE</wicri:noCountry></affiliation></author><author><name sortKey="Deinert, M" sort="Deinert, M" uniqKey="Deinert M" first="M" last="Deinert">M. Deinert</name><affiliation wicri:level="1"><nlm:affiliation>Tierklinik am Sandpfad, Wiesloch, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Tierklinik am Sandpfad, Wiesloch</wicri:regionArea><wicri:noRegion>Wiesloch</wicri:noRegion><wicri:noRegion>Wiesloch</wicri:noRegion><wicri:noRegion>Wiesloch</wicri:noRegion></affiliation></author><author><name sortKey="Bomassi, E" sort="Bomassi, E" uniqKey="Bomassi E" first="E" last="Bomassi">E. Bomassi</name><affiliation wicri:level="3"><nlm:affiliation>Cardiology, Centre Hospitalier Vétérinaire des Cordeliers, Meaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Cardiology, Centre Hospitalier Vétérinaire des Cordeliers, Meaux</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Meaux</settlement></placeName></affiliation></author><author><name sortKey="Estrada, A H" sort="Estrada, A H" uniqKey="Estrada A" first="A H" last="Estrada">A H Estrada</name><affiliation wicri:level="2"><nlm:affiliation>Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, FL.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville</wicri:cityArea></affiliation></author><author><name sortKey="Fernandez Del Palacio, M J" sort="Fernandez Del Palacio, M J" uniqKey="Fernandez Del Palacio M" first="M J" last="Fernandez Del Palacio">M J Fernandez Del Palacio</name><affiliation wicri:level="1"><nlm:affiliation>Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Murcia, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Murcia</wicri:regionArea><wicri:noRegion>Murcia</wicri:noRegion></affiliation></author><author><name sortKey="Moise, N S" sort="Moise, N S" uniqKey="Moise N" first="N S" last="Moise">N S Moise</name><affiliation wicri:level="2"><nlm:affiliation>Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca</wicri:cityArea></affiliation></author><author><name sortKey="Abbott, J A" sort="Abbott, J A" uniqKey="Abbott J" first="J A" last="Abbott">J A Abbott</name><affiliation wicri:level="2"><nlm:affiliation>Department of Small Animal Clinical Sciences, Virginia Tech, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Virginie</region></placeName><wicri:cityArea>Department of Small Animal Clinical Sciences, Virginia Tech, Virginia-Maryland College of Veterinary Medicine, Blacksburg</wicri:cityArea></affiliation></author><author><name sortKey="Fujii, Y" sort="Fujii, Y" uniqKey="Fujii Y" first="Y" last="Fujii">Y. Fujii</name><affiliation wicri:level="1"><nlm:affiliation>Azabu University, Chuo-ku, Sagamihara, Kanagawa, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Azabu University, Chuo-ku, Sagamihara, Kanagawa</wicri:regionArea><wicri:noRegion>Kanagawa</wicri:noRegion></affiliation></author><author><name sortKey="Spier, A" sort="Spier, A" uniqKey="Spier A" first="A" last="Spier">A. Spier</name><affiliation wicri:level="2"><nlm:affiliation>Blue Pearl Veterinary Partners, Tampa, FL.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Blue Pearl Veterinary Partners, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Luethy, M W" sort="Luethy, M W" uniqKey="Luethy M" first="M W" last="Luethy">M W Luethy</name><affiliation wicri:level="2"><nlm:affiliation>Chicago Veterinary Emergency and Specialty Center, Chicago, IL.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Illinois</region></placeName><wicri:cityArea>Chicago Veterinary Emergency and Specialty Center, Chicago</wicri:cityArea></affiliation></author><author><name sortKey="Santilli, R A" sort="Santilli, R A" uniqKey="Santilli R" first="R A" last="Santilli">R A Santilli</name><affiliation wicri:level="1"><nlm:affiliation>Cardiology, Clinica Veterinaria Malpensa, Viale Marconi, Varese, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Cardiology, Clinica Veterinaria Malpensa, Viale Marconi, Varese</wicri:regionArea><wicri:noRegion>Varese</wicri:noRegion></affiliation></author><author><name sortKey="Uechi, M" sort="Uechi, M" uniqKey="Uechi M" first="M" last="Uechi">M. Uechi</name><affiliation wicri:level="1"><nlm:affiliation>JASMINE Veterinary Cardiovascular Medical Center, Japan Animal Specialty Medical Institute Inc., Yokohama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>JASMINE Veterinary Cardiovascular Medical Center, Japan Animal Specialty Medical Institute Inc., Yokohama</wicri:regionArea><wicri:noRegion>Yokohama</wicri:noRegion></affiliation></author><author><name sortKey="Tidholm, A" sort="Tidholm, A" uniqKey="Tidholm A" first="A" last="Tidholm">A. Tidholm</name><affiliation wicri:level="1"><nlm:affiliation>Djursjukhuset Albano, Danderyd, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Djursjukhuset Albano, Danderyd</wicri:regionArea><wicri:noRegion>Danderyd</wicri:noRegion></affiliation></author><author><name sortKey="Watson, P" sort="Watson, P" uniqKey="Watson P" first="P" last="Watson">P. Watson</name><affiliation wicri:level="1"><nlm:affiliation>Boehringer Ingelheim, Animal Health, Ingelheim am Rhein, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Boehringer Ingelheim, Animal Health, Ingelheim am Rhein</wicri:regionArea><wicri:noRegion>Ingelheim am Rhein</wicri:noRegion><wicri:noRegion>Ingelheim am Rhein</wicri:noRegion><wicri:noRegion>Ingelheim am Rhein</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of veterinary internal medicine</title><idno type="eISSN">1939-1676</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Pimobendan is effective in treatment of dogs with congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Its effect on dogs before the onset of CHF is unknown.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">27678080</PMID><DateCreated><Year>2016</Year><Month>09</Month><Day>28</Day></DateCreated><DateRevised><Year>2017</Year><Month>02</Month><Day>20</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1939-1676</ISSN><JournalIssue CitedMedium="Internet"><Volume>30</Volume><Issue>6</Issue><PubDate><Year>2016</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Journal of veterinary internal medicine</Title><ISOAbbreviation>J. Vet. Intern. Med.</ISOAbbreviation></Journal><ArticleTitle>Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial.</ArticleTitle><Pagination><MedlinePgn>1765-1779</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/jvim.14586</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Pimobendan is effective in treatment of dogs with congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Its effect on dogs before the onset of CHF is unknown.</AbstractText><AbstractText Label="HYPOTHESIS/OBJECTIVES" NlmCategory="OBJECTIVE">Administration of pimobendan (0.4-0.6 mg/kg/d in divided doses) to dogs with increased heart size secondary to preclinical MMVD, not receiving other cardiovascular medications, will delay the onset of signs of CHF, cardiac-related death, or euthanasia.</AbstractText><AbstractText Label="ANIMALS" NlmCategory="METHODS">360 client-owned dogs with MMVD with left atrial-to-aortic ratio ≥1.6, normalized left ventricular internal diameter in diastole ≥1.7, and vertebral heart sum >10.5.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Prospective, randomized, placebo-controlled, blinded, multicenter clinical trial. Primary outcome variable was time to a composite of the onset of CHF, cardiac-related death, or euthanasia.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Median time to primary endpoint was 1228 days (95% CI: 856-NA) in the pimobendan group and 766 days (95% CI: 667-875) in the placebo group (P = .0038). Hazard ratio for the pimobendan group was 0.64 (95% CI: 0.47-0.87) compared with the placebo group. The benefit persisted after adjustment for other variables. Adverse events were not different between treatment groups. Dogs in the pimobendan group lived longer (median survival time was 1059 days (95% CI: 952-NA) in the pimobendan group and 902 days (95% CI: 747-1061) in the placebo group) (P = .012).</AbstractText><AbstractText Label="CONCLUSIONS AND CLINICAL IMPORTANCE" NlmCategory="CONCLUSIONS">Administration of pimobendan to dogs with MMVD and echocardiographic and radiographic evidence of cardiomegaly results in prolongation of preclinical period and is safe and well tolerated. Prolongation of preclinical period by approximately 15 months represents substantial clinical benefit.</AbstractText><CopyrightInformation>Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Boswood</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hatfield, Hertfordshire, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Häggström</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, SE.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gordon</LastName><ForeName>S G</ForeName><Initials>SG</Initials><AffiliationInfo><Affiliation>Small Animal Clinical Science, Texas A&M University, College Station, TX.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wess</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Clinic of Small Animal Medicine, University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stepien</LastName><ForeName>R L</ForeName><Initials>RL</Initials><AffiliationInfo><Affiliation>Medical Sciences, University of Wisconsin Madison School of Veterinary Medicine, Madison, WI.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oyama</LastName><ForeName>M A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Clinical Studies-Philadelphia, MJR-VHUP-Cardiology, University of Pennsylvania, Philadelphia, PA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keene</LastName><ForeName>B W</ForeName><Initials>BW</Initials><AffiliationInfo><Affiliation>Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bonagura</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>MacDonald</LastName><ForeName>K A</ForeName><Initials>KA</Initials><AffiliationInfo><Affiliation>Animal Care Center, Rohnert Park, CA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Patteson</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>HeartVets @ Vale Referrals, The Animal Hospital, Dursley, Gloucestershire, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Sarah Smith Cardiology, Derby, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>P R</ForeName><Initials>PR</Initials><AffiliationInfo><Affiliation>Animal Medical Center, New York, NY.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanderson</LastName><ForeName>K</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Rocky Mountain Veterinary Cardiology, Boulder, CO.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Woolley</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Cardio Respiratory Pet Referrals Victoria, Mordialloc, Vic, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Szatmári</LastName><ForeName>V</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Faculty of Veterinary Medicine, Clinical Sciences of Companion Animals, Utrecht University, Utrecht, Utrecht, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Menaut</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Internal Medicine and Cardiology, Clinique Vétérinaire Aquivet, Eysines, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Church</LastName><ForeName>W M</ForeName><Initials>WM</Initials><AffiliationInfo><Affiliation>Desert Veterinary Medical Specialists, Phoenix, AZ.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Sullivan</LastName><ForeName>M L</ForeName><Initials>ML</Initials><AffiliationInfo><Affiliation>Deptartment of Clinical Studies, University of Guelph, Ontario Veterinary College, Guelph, ON, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jaudon</LastName><ForeName>J-P</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Clinique Veterinaire Des Etangs, Villars Les Dombes, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kresken</LastName><ForeName>J-G</ForeName><Initials>JG</Initials><AffiliationInfo><Affiliation>Clinic for Small Animals Kaiserberg, Duisburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rush</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Clinical Sciences, Tufts University Cummings School of Veterinary Medicine, North Grafton, MA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barrett</LastName><ForeName>K A</ForeName><Initials>KA</Initials><AffiliationInfo><Affiliation>Cardiology, VCA West Los Angeles, Los Angeles, CA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rosenthal</LastName><ForeName>S L</ForeName><Initials>SL</Initials><AffiliationInfo><Affiliation>Cardiac Care for Pets, Towson, MD.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saunders</LastName><ForeName>A B</ForeName><Initials>AB</Initials><AffiliationInfo><Affiliation>Small Animal Clinical Science, Texas A&M University, College Station, TX.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ljungvall</LastName><ForeName>I</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, SE.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Deinert</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Tierklinik am Sandpfad, Wiesloch, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bomassi</LastName><ForeName>E</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Cardiology, Centre Hospitalier Vétérinaire des Cordeliers, Meaux, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Estrada</LastName><ForeName>A H</ForeName><Initials>AH</Initials><AffiliationInfo><Affiliation>Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, FL.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fernandez Del Palacio</LastName><ForeName>M J</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Murcia, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moise</LastName><ForeName>N S</ForeName><Initials>NS</Initials><AffiliationInfo><Affiliation>Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abbott</LastName><ForeName>J A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Department of Small Animal Clinical Sciences, Virginia Tech, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fujii</LastName><ForeName>Y</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Azabu University, Chuo-ku, Sagamihara, Kanagawa, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spier</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Blue Pearl Veterinary Partners, Tampa, FL.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luethy</LastName><ForeName>M W</ForeName><Initials>MW</Initials><AffiliationInfo><Affiliation>Chicago Veterinary Emergency and Specialty Center, Chicago, IL.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Santilli</LastName><ForeName>R A</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>Cardiology, Clinica Veterinaria Malpensa, Viale Marconi, Varese, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Uechi</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>JASMINE Veterinary Cardiovascular Medical Center, Japan Animal Specialty Medical Institute Inc., Yokohama, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tidholm</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Djursjukhuset Albano, Danderyd, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Watson</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Boehringer Ingelheim, Animal Health, Ingelheim am Rhein, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>09</Month><Day>28</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Vet Intern Med</MedlineTA><NlmUniqueID>8708660</NlmUniqueID><ISSNLinking>0891-6640</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Vet Radiol Ultrasound. 2002 Nov-Dec;43(6):568-75</RefSource><PMID Version="1">12502113</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>CMAJ. 2004 Feb 17;170(4):477-80</RefSource><PMID Version="1">14970094</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Am Vet Med Assoc. 2007 Oct 1;231(7):1061-9</RefSource><PMID Version="1">17916031</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Vet Intern Med. 2009 Nov-Dec;23(6):1142-50</RefSource><PMID Version="1">19780929</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biometrics. 1979 Sep;35(3):549-56</RefSource><PMID Version="1">497341</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Vet 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PubStatus="accepted"><Year>2016</Year><Month>08</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>9</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>9</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>9</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27678080</ArticleId><ArticleId IdType="doi">10.1111/jvim.14586</ArticleId><ArticleId 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H Ggström</name><name sortKey="Ljungvall, I" sort="Ljungvall, I" uniqKey="Ljungvall I" first="I" last="Ljungvall">I. Ljungvall</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Boswood, A" sort="Boswood, A" uniqKey="Boswood A" first="A" last="Boswood">A. Boswood</name></noRegion><name sortKey="Patteson, M" sort="Patteson, M" uniqKey="Patteson M" first="M" last="Patteson">M. Patteson</name><name sortKey="Smith, S" sort="Smith, S" uniqKey="Smith S" first="S" last="Smith">S. 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Rush</name><name sortKey="Sanderson, K" sort="Sanderson, K" uniqKey="Sanderson K" first="K" last="Sanderson">K. Sanderson</name><name sortKey="Saunders, A B" sort="Saunders, A B" uniqKey="Saunders A" first="A B" last="Saunders">A B Saunders</name><name sortKey="Spier, A" sort="Spier, A" uniqKey="Spier A" first="A" last="Spier">A. Spier</name><name sortKey="Stepien, R L" sort="Stepien, R L" uniqKey="Stepien R" first="R L" last="Stepien">R L Stepien</name></country><country name="Allemagne"><region name="Bavière"><name sortKey="Wess, G" sort="Wess, G" uniqKey="Wess G" first="G" last="Wess">G. Wess</name></region><name sortKey="Deinert, M" sort="Deinert, M" uniqKey="Deinert M" first="M" last="Deinert">M. Deinert</name><name sortKey="Kresken, J G" sort="Kresken, J G" uniqKey="Kresken J" first="J-G" last="Kresken">J-G Kresken</name><name sortKey="Watson, P" sort="Watson, P" uniqKey="Watson P" first="P" last="Watson">P. Watson</name></country><country name="Australie"><noRegion><name sortKey="Woolley, R" sort="Woolley, R" uniqKey="Woolley R" first="R" last="Woolley">R. Woolley</name></noRegion></country><country name="Pays-Bas"><region name="Utrecht (province)"><name sortKey="Szatmari, V" sort="Szatmari, V" uniqKey="Szatmari V" first="V" last="Szatmári">V. Szatmári</name></region></country><country name="France"><noRegion><name sortKey="Menaut, P" sort="Menaut, P" uniqKey="Menaut P" first="P" last="Menaut">P. Menaut</name></noRegion><name sortKey="Bomassi, E" sort="Bomassi, E" uniqKey="Bomassi E" first="E" last="Bomassi">E. Bomassi</name><name sortKey="Jaudon, J P" sort="Jaudon, J P" uniqKey="Jaudon J" first="J-P" last="Jaudon">J-P Jaudon</name></country><country name="Canada"><noRegion><name sortKey="O Sullivan, M L" sort="O Sullivan, M L" uniqKey="O Sullivan M" first="M L" last="O'Sullivan">M L O'Sullivan</name></noRegion></country><country name="Espagne"><noRegion><name sortKey="Fernandez Del Palacio, M J" sort="Fernandez Del Palacio, M J" uniqKey="Fernandez Del Palacio M" first="M J" last="Fernandez Del Palacio">M J Fernandez Del Palacio</name></noRegion></country><country name="Japon"><noRegion><name sortKey="Fujii, Y" sort="Fujii, Y" uniqKey="Fujii Y" first="Y" last="Fujii">Y. Fujii</name></noRegion><name sortKey="Uechi, M" sort="Uechi, M" uniqKey="Uechi M" first="M" last="Uechi">M. Uechi</name></country><country name="Italie"><noRegion><name sortKey="Santilli, R A" sort="Santilli, R A" uniqKey="Santilli R" first="R A" last="Santilli">R A Santilli</name></noRegion></country><country name="Suède"><noRegion><name sortKey="Tidholm, A" sort="Tidholm, A" uniqKey="Tidholm A" first="A" last="Tidholm">A. Tidholm</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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