New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Identifieur interne : 001991 ( PubMed/Checkpoint ); précédent : 001990; suivant : 001992New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Auteurs : Yingchang Lu [États-Unis] ; Felix R. Day [Royaume-Uni] ; Stefan Gustafsson [Suède] ; Martin L. Buchkovich [États-Unis] ; Jianbo Na [États-Unis] ; Veronique Bataille [Royaume-Uni] ; Diana L. Cousminer [Finlande] ; Zari Dastani [Canada] ; Alexander W. Drong [Royaume-Uni] ; T Nu Esko [Estonie] ; David M. Evans [Australie] ; Mario Falchi [Royaume-Uni] ; Mary F. Feitosa [États-Unis] ; Teresa Ferreira [Royaume-Uni] ; Sa K. Hedman [Suède] ; Robin Haring [Allemagne] ; Pirro G. Hysi [Royaume-Uni] ; Mark M. Iles [Royaume-Uni] ; Anne E. Justice [États-Unis] ; Stavroula Kanoni [Royaume-Uni] ; Vasiliki Lagou [Royaume-Uni] ; Rui Li [Canada] ; Xin Li [États-Unis] ; Adam Locke [États-Unis] ; Chen Lu [États-Unis] ; Reedik M Gi [Royaume-Uni] ; John R B. Perry [Royaume-Uni] ; Tune H. Pers [États-Unis] ; Qibin Qi [États-Unis] ; Marianna Sanna [Royaume-Uni] ; Ellen M. Schmidt [États-Unis] ; William R. Scott [Royaume-Uni] ; Dmitry Shungin [Suède] ; Alexander Teumer [Allemagne] ; Anna A E. Vinkhuyzen [Australie] ; Ryan W. Walker [États-Unis] ; Harm-Jan Westra [États-Unis] ; Mingfeng Zhang [États-Unis] ; Weihua Zhang [Royaume-Uni] ; Jing Hua Zhao [Royaume-Uni] ; Zhihong Zhu [Australie] ; Uzma Afzal [Royaume-Uni] ; Tarunveer Singh Ahluwalia [Danemark] ; Stephan J L. Bakker [Pays-Bas] ; Claire Bellis [États-Unis] ; Amélie Bonnefond [France] ; Katja Borodulin [Finlande] ; Aron S. Buchman [États-Unis] ; Tommy Cederholm [Suède] ; Audrey C. Choh [États-Unis] ; Hyung Jin Choi [Corée du Sud] ; Joanne E. Curran [États-Unis] ; Lisette C P G M. De Groot [Pays-Bas] ; Philip L. De Jager [États-Unis] ; Rosalie A M. Dhonukshe-Rutten [Pays-Bas] ; Anke W. Enneman [Pays-Bas] ; Elodie Eury [France] ; Daniel S. Evans [États-Unis] ; Tom Forsen [Finlande] ; Nele Friedrich [Allemagne] ; Frédéric Fumeron [France] ; Melissa E. Garcia [États-Unis] ; Simone G Rtner [Allemagne] ; Bok-Ghee Han [Corée du Sud] ; Aki S. Havulinna [Finlande] ; Caroline Hayward [Royaume-Uni] ; Dena Hernandez [États-Unis] ; Hans Hillege [Pays-Bas] ; Till Ittermann [Allemagne] ; Jack W. Kent [États-Unis] ; Ivana Kolcic [Croatie] ; Tiina Laatikainen [Finlande] ; Jari Lahti [Finlande] ; Irene Mateo Leach [Pays-Bas] ; Christine G. Lee [États-Unis] ; Jong-Young Lee [Corée du Sud] ; Tian Liu [Allemagne] ; Youfang Liu [États-Unis] ; Stéphane Lobbens [France] ; Marie Loh [Royaume-Uni] ; Leo-Pekka Lyytik Inen [Finlande] ; Carolina Medina-Gomez [Pays-Bas] ; Karl Michaëlsson [Suède] ; Mike A. Nalls [États-Unis] ; Carrie M. Nielson [États-Unis] ; Laticia Oozageer [Royaume-Uni] ; Laura Pascoe [Royaume-Uni] ; Lavinia Paternoster ; Ozren Polašek [Croatie] ; Samuli Ripatti [Finlande] ; Mark A. Sarzynski [États-Unis] ; Chan Soo Shin [Corée du Sud] ; Nina Smolej Naran I [Croatie] ; Dominik Spira [Allemagne] ; Priya Srikanth [États-Unis] ; Elisabeth Steinhagen-Thiessen [Allemagne] ; Yun Ju Sung [États-Unis] ; Karin M A. Swart [Pays-Bas] ; Leena Taittonen [Finlande] ; Toshiko Tanaka [États-Unis] ; Emmi Tikkanen [Finlande] ; Nathalie Van Der Velde [Pays-Bas] ; Natasja M. Van Schoor [Pays-Bas] ; Niek Verweij [Pays-Bas] ; Alan F. Wright [Royaume-Uni] ; Lei Yu [États-Unis] ; Joseph M. Zmuda [États-Unis] ; Niina Eklund [Finlande] ; Terrence Forrester [Jamaïque] ; Niels Grarup [Danemark] ; Anne U. Jackson [États-Unis] ; Kati Kristiansson [Finlande] ; Teemu Kuulasmaa [Finlande] ; Johanna Kuusisto [Finlande] ; Peter Lichtner [Allemagne] ; Jian'An Luan [Royaume-Uni] ; Anubha Mahajan [Royaume-Uni] ; Satu M Nnistö [Finlande] ; Cameron D. Palmer [États-Unis] ; Janina S. Ried [Allemagne] ; Robert A. Scott [Royaume-Uni] ; Alena Stancáková [Finlande] ; Peter J. Wagner [Finlande] ; Ayse Demirkan [Pays-Bas] ; Angela Döring [Allemagne] ; Vilmundur Gudnason [Islande] ; Douglas P. Kiel [États-Unis] ; Brigitte Kühnel [Allemagne] ; Massimo Mangino [Royaume-Uni] ; Barbara Mcknight [États-Unis] ; Cristina Menni [Royaume-Uni] ; Jeffrey R. O'Connell [États-Unis] ; Ben A. Oostra [Pays-Bas] ; Alan R. Shuldiner [États-Unis] ; Kijoung Song [États-Unis] ; Liesbeth Vandenput [Suède] ; Cornelia M. Van Duijn ; Peter Vollenweider [Suisse] ; Charles C. White [États-Unis] ; Michael Boehnke [États-Unis] ; Yvonne Boettcher [Allemagne] ; Richard S. Cooper [États-Unis] ; Nita G. Forouhi [Royaume-Uni] ; Christian Gieger [Allemagne] ; Harald Grallert [Allemagne] ; Aroon Hingorani [Royaume-Uni] ; Torben J Rgensen [Danemark] ; Pekka Jousilahti [Finlande] ; Mika Kivimaki [Royaume-Uni] ; Meena Kumari [Royaume-Uni] ; Markku Laakso [Finlande] ; Claudia Langenberg [Royaume-Uni] ; Allan Linneberg [Danemark] ; Amy Luke [États-Unis] ; Colin A. Mckenzie [Jamaïque] ; Aarno Palotie [Finlande] ; Oluf Pedersen [Danemark] ; Annette Peters [Allemagne] ; Konstantin Strauch [Allemagne] ; Bamidele O. Tayo [États-Unis] ; Nicholas J. Wareham [Royaume-Uni] ; David A. Bennett [États-Unis] ; Lars Bertram [Royaume-Uni] ; John Blangero [États-Unis] ; Matthias Blüher [Allemagne] ; Claude Bouchard [États-Unis] ; Harry Campbell [Royaume-Uni] ; Nam H. Cho [Corée du Sud] ; Steven R. Cummings [États-Unis] ; Stefan A. Czerwinski [États-Unis] ; Ilja Demuth [Allemagne] ; Rahel Eckardt [Allemagne] ; Johan G. Eriksson [Finlande] ; Luigi Ferrucci [États-Unis] ; Oscar H. Franco ; Philippe Froguel [France] ; Ron T. Gansevoort [Pays-Bas] ; Torben Hansen [Danemark] ; Tamara B. Harris [États-Unis] ; Nicholas Hastie [Royaume-Uni] ; Markku Heliövaara [Finlande] ; Albert Hofman ; Joanne M. Jordan [États-Unis] ; Antti Jula [Finlande] ; Mika K Hönen [Finlande] ; Eero Kajantie [Finlande] ; Paul B. Knekt [Finlande] ; Seppo Koskinen [Finlande] ; Peter Kovacs [Allemagne] ; Terho Lehtim Ki [Finlande] ; Lars Lind [Suède] ; Yongmei Liu [États-Unis] ; Eric S. Orwoll [États-Unis] ; Clive Osmond [Royaume-Uni] ; Markus Perola [Finlande] ; Louis Pérusse [Canada] ; Olli T. Raitakari [Finlande] ; Tuomo Rankinen [États-Unis] ; D C Rao [États-Unis] ; Treva K. Rice [États-Unis] ; Fernando Rivadeneira [Pays-Bas] ; Igor Rudan [Royaume-Uni] ; Veikko Salomaa [Finlande] ; Thorkild I A. S Rensen ; Michael Stumvoll [Allemagne] ; Anke Tönjes [Allemagne] ; Bradford Towne [États-Unis] ; Gregory J. Tranah [États-Unis] ; Angelo Tremblay [Canada] ; André G. Uitterlinden [Pays-Bas] ; Pim Van Der Harst [Pays-Bas] ; Erkki Vartiainen [Finlande] ; Jorma S. Viikari [Finlande] ; Veronique Vitart [Royaume-Uni] ; Marie-Claude Vohl [Canada] ; Henry Völzke [Allemagne] ; Mark Walker [États-Unis] ; Henri Wallaschofski [Allemagne] ; Sarah Wild [Royaume-Uni] ; James F. Wilson [Royaume-Uni] ; Loïc Yengo [France] ; D Timothy Bishop [Royaume-Uni] ; Ingrid B. Borecki [États-Unis] ; John C. Chambers [Royaume-Uni] ; L Adrienne Cupples [États-Unis] ; Abbas Dehghan [Pays-Bas] ; Panos Deloukas [Royaume-Uni] ; Ghazaleh Fatemifar ; Caroline Fox [États-Unis] ; Terrence S. Furey [États-Unis] ; Lude Franke [Pays-Bas] ; Jiali Han [États-Unis] ; David J. Hunter [États-Unis] ; Juha Karjalainen [Pays-Bas] ; Fredrik Karpe [Royaume-Uni] ; Robert C. Kaplan [États-Unis] ; Jaspal S. Kooner [Royaume-Uni] ; Mark I. Mccarthy [Royaume-Uni] ; Joanne M. Murabito [États-Unis] ; Andrew P. Morris [Royaume-Uni] ; Julia A N. Bishop [Royaume-Uni] ; Kari E. North [États-Unis] ; Claes Ohlsson [Suède] ; Ken K. Ong [Royaume-Uni] ; Inga Prokopenko [Royaume-Uni] ; J Brent Richards [Canada] ; Eric E. Schadt [États-Unis] ; Tim D. Spector [Royaume-Uni] ; Elisabeth Widén [Finlande] ; Cristen J. Willer [États-Unis] ; Jian Yang [Australie] ; Erik Ingelsson [Suède] ; Karen L. Mohlke [États-Unis] ; Joel N. Hirschhorn [États-Unis] ; John Andrew Pospisilik [Allemagne] ; M Carola Zillikens [Pays-Bas] ; Cecilia Lindgren [Royaume-Uni] ; Tuomas Oskari Kilpel Inen [Royaume-Uni] ; Ruth J F. Loos [États-Unis]Source :
- Nature communications [ 2041-1723 ] ; 2016.
Descripteurs français
- KwdFr :
- Adiposité (génétique), Animaux, Cardiopathies (génétique), Drosophila melanogaster (génétique), Drosophila melanogaster (métabolisme), Humains, Locus de caractère quantitatif (génétique), Prédisposition génétique à une maladie, Régulation de l'expression des gènes (physiologie), Techniques de knock-down de gènes, Étude d'association pangénomique.
- MESH :
- génétique : Adiposité, Cardiopathies, Drosophila melanogaster, Locus de caractère quantitatif.
- métabolisme : Drosophila melanogaster.
- physiologie : Régulation de l'expression des gènes.
- Animaux, Humains, Prédisposition génétique à une maladie, Techniques de knock-down de gènes, Étude d'association pangénomique.
English descriptors
- KwdEn :
- Adiposity (genetics), Animals, Drosophila melanogaster (genetics), Drosophila melanogaster (metabolism), Gene Expression Regulation (physiology), Gene Knockdown Techniques, Genetic Predisposition to Disease, Genome-Wide Association Study, Heart Diseases (genetics), Humans, Quantitative Trait Loci (genetics).
- MESH :
- genetics : Adiposity, Drosophila melanogaster, Heart Diseases, Quantitative Trait Loci.
- metabolism : Drosophila melanogaster.
- physiology : Gene Expression Regulation.
- Animals, Gene Knockdown Techniques, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans.
Abstract
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals. Twelve loci reached genome-wide significance (P<5 × 10(-8)), of which eight were previously associated with increased overall adiposity (BMI, BF%) and four (in or near COBLL1/GRB14, IGF2BP1, PLA2G6, CRTC1) were novel associations with BF%. Seven loci showed a larger effect on BF% than on BMI, suggestive of a primary association with adiposity, while five loci showed larger effects on BMI than on BF%, suggesting association with both fat and lean mass. In particular, the loci more strongly associated with BF% showed distinct cross-phenotype association signatures with a range of cardiometabolic traits revealing new insights in the link between adiposity and disease risk.
DOI: 10.1038/ncomms10495
PubMed: 26833246
Affiliations:
- Allemagne, Australie, Canada, Corée du Sud, Croatie, Danemark, Estonie, Finlande, France, Islande, Jamaïque, Pays-Bas, Royaume-Uni, Suisse, Suède, États-Unis
- Angleterre, Bade-Wurtemberg, Berlin, Californie, Canton de Vaud, Caroline du Nord, District de Karlsruhe, District de Leipzig, East Middle Sweden, Finlande occidentale, Grand Londres, Groningue (province), Gueldre (province), Hollande-Méridionale, Hovedstaden, Massachusetts, Missouri (État), Oregon, Oxfordshire, Pennsylvanie, Québec, Région capitale de Séoul, Saxe (Land), Svealand, Texas, Uusimaa, Washington (État), Yorkshire-et-Humber, Écosse
- Berlin, Chapel Hill (Caroline du Nord), Copenhague, Groningue (ville), Helsinki, Karlsruhe, Lausanne, Leeds, Leipzig, Londres, Los Angeles, Montréal, Oxford, Pittsburgh, Portland, Rotterdam, Saint-Louis (Missouri), Seattle, Séoul, Turku, Uppsala, Wageningue, Édimbourg
- University College de Londres, Université McGill, Université d'Helsinki, Université d'Oxford, Université d'Uppsala, Université d'Édimbourg, Université de Caroline du Nord à Chapel Hill, Université de Groningue, Université de Leeds, Université de Londres, Université de Pittsburgh, Université de Turku, Université de Wageningue, Université de Washington, Université des sciences et de la médecine de l'Oregon, École de médecine (Université Washington de Saint-Louis)
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pubmed:26833246Le document en format XML
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Cousminer</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Dastani, Zari" sort="Dastani, Zari" uniqKey="Dastani Z" first="Zari" last="Dastani">Zari Dastani</name><affiliation wicri:level="4"><nlm:affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Drong, Alexander W" sort="Drong, Alexander W" uniqKey="Drong A" first="Alexander W" last="Drong">Alexander W. 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Evans</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland 4102, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland 4102</wicri:regionArea><wicri:noRegion>Queensland 4102</wicri:noRegion></affiliation></author><author><name sortKey="Falchi, Mario" sort="Falchi, Mario" uniqKey="Falchi M" first="Mario" last="Falchi">Mario Falchi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F" last="Feitosa">Mary F. Feitosa</name><affiliation wicri:level="4"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Hedman, Sa K" sort="Hedman, Sa K" uniqKey="Hedman " first=" Sa K" last="Hedman"> Sa K. Hedman</name><affiliation wicri:level="4"><nlm:affiliation>Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, 750 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Haring, Robin" sort="Haring, Robin" uniqKey="Haring R" first="Robin" last="Haring">Robin Haring</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Iles, Mark M" sort="Iles, Mark M" uniqKey="Iles M" first="Mark M" last="Iles">Mark M. Iles</name><affiliation wicri:level="4"><nlm:affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="Justice, Anne E" sort="Justice, Anne E" uniqKey="Justice A" first="Anne E" last="Justice">Anne E. Justice</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599</wicri:regionArea><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName><placeName><settlement type="city">Chapel Hill (Caroline du Nord)</settlement><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><affiliation wicri:level="4"><nlm:affiliation>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ</wicri:regionArea><orgName type="university">Université de Londres</orgName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Li, Rui" sort="Li, Rui" uniqKey="Li R" first="Rui" last="Li">Rui Li</name><affiliation wicri:level="4"><nlm:affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Li, Xin" sort="Li, Xin" uniqKey="Li X" first="Xin" last="Li">Xin Li</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115</wicri:regionArea><wicri:noRegion>Massachusetts 02115</wicri:noRegion></affiliation></author><author><name sortKey="Locke, Adam" sort="Locke, Adam" uniqKey="Locke A" first="Adam" last="Locke">Adam Locke</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Chen" sort="Lu, Chen" uniqKey="Lu C" first="Chen" last="Lu">Chen Lu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R B" last="Perry">John R B. Perry</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H" last="Pers">Tune H. Pers</name><affiliation wicri:level="1"><nlm:affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115</wicri:regionArea><wicri:noRegion>Massachusetts 02115</wicri:noRegion></affiliation></author><author><name sortKey="Qi, Qibin" sort="Qi, Qibin" uniqKey="Qi Q" first="Qibin" last="Qi">Qibin Qi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461</wicri:regionArea><wicri:noRegion>New York 10461</wicri:noRegion></affiliation></author><author><name sortKey="Sanna, Marianna" sort="Sanna, Marianna" uniqKey="Sanna M" first="Marianna" last="Sanna">Marianna Sanna</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Schmidt, Ellen M" sort="Schmidt, Ellen M" uniqKey="Schmidt E" first="Ellen M" last="Schmidt">Ellen M. Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Scott, William R" sort="Scott, William R" uniqKey="Scott W" first="William R" last="Scott">William R. Scott</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Shungin, Dmitry" sort="Shungin, Dmitry" uniqKey="Shungin D" first="Dmitry" last="Shungin">Dmitry Shungin</name><affiliation wicri:level="1"><nlm:affiliation>Lund University Diabetes Centre, Department of Clinical Science, Genetic and Molecular Epidemiology Unit, Skåne University Hosptial, 205 02 Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science, Genetic and Molecular Epidemiology Unit, Skåne University Hosptial, 205 02 Malmö</wicri:regionArea><wicri:noRegion>205 02 Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Vinkhuyzen, Anna A E" sort="Vinkhuyzen, Anna A E" uniqKey="Vinkhuyzen A" first="Anna A E" last="Vinkhuyzen">Anna A E. Vinkhuyzen</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, The University of Queensland, Brisbane 4072</wicri:regionArea><wicri:noRegion>Brisbane 4072</wicri:noRegion></affiliation></author><author><name sortKey="Walker, Ryan W" sort="Walker, Ryan W" uniqKey="Walker R" first="Ryan W" last="Walker">Ryan W. Walker</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029</wicri:regionArea><wicri:noRegion>New York 10029</wicri:noRegion></affiliation></author><author><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Mingfeng" sort="Zhang, Mingfeng" uniqKey="Zhang M" first="Mingfeng" last="Zhang">Mingfeng Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts 02115</wicri:regionArea><wicri:noRegion>Massachusetts 02115</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Zhu, Zhihong" sort="Zhu, Zhihong" uniqKey="Zhu Z" first="Zhihong" last="Zhu">Zhihong Zhu</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, The University of Queensland, Brisbane 4072</wicri:regionArea><wicri:noRegion>Brisbane 4072</wicri:noRegion></affiliation></author><author><name sortKey="Afzal, Uzma" sort="Afzal, Uzma" uniqKey="Afzal U" first="Uzma" last="Afzal">Uzma Afzal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Ahluwalia, Tarunveer Singh" sort="Ahluwalia, Tarunveer Singh" uniqKey="Ahluwalia T" first="Tarunveer Singh" last="Ahluwalia">Tarunveer Singh Ahluwalia</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Bakker, Stephan J L" sort="Bakker, Stephan J L" uniqKey="Bakker S" first="Stephan J L" last="Bakker">Stephan J L. Bakker</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245</wicri:regionArea><wicri:noRegion>Texas 78245</wicri:noRegion></affiliation></author><author><name sortKey="Bonnefond, Amelie" sort="Bonnefond, Amelie" uniqKey="Bonnefond A" first="Amélie" last="Bonnefond">Amélie Bonnefond</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Borodulin, Katja" sort="Borodulin, Katja" uniqKey="Borodulin K" first="Katja" last="Borodulin">Katja Borodulin</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Buchman, Aron S" sort="Buchman, Aron S" uniqKey="Buchman A" first="Aron S" last="Buchman">Aron S. Buchman</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612</wicri:regionArea><wicri:noRegion>Illinois 60612</wicri:noRegion></affiliation></author><author><name sortKey="Cederholm, Tommy" sort="Cederholm, Tommy" uniqKey="Cederholm T" first="Tommy" last="Cederholm">Tommy Cederholm</name><affiliation wicri:level="4"><nlm:affiliation>Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 751 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 751 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Choh, Audrey C" sort="Choh, Audrey C" uniqKey="Choh A" first="Audrey C" last="Choh">Audrey C. Choh</name><affiliation wicri:level="1"><nlm:affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420</wicri:regionArea><wicri:noRegion>Ohio 45420</wicri:noRegion></affiliation></author><author><name sortKey="Choi, Hyung Jin" sort="Choi, Hyung Jin" uniqKey="Choi H" first="Hyung Jin" last="Choi">Hyung Jin Choi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Anatomy, Seoul National University College of Medicine, Seoul 03080, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Anatomy, Seoul National University College of Medicine, Seoul 03080</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Curran, Joanne E" sort="Curran, Joanne E" uniqKey="Curran J" first="Joanne E" last="Curran">Joanne E. Curran</name><affiliation wicri:level="2"><nlm:affiliation>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville</wicri:cityArea></affiliation></author><author><name sortKey="De Groot, Lisette C P G M" sort="De Groot, Lisette C P G M" uniqKey="De Groot L" first="Lisette C P G M" last="De Groot">Lisette C P G M. De Groot</name><affiliation wicri:level="4"><nlm:affiliation>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen</wicri:regionArea><orgName type="university">Université de Wageningue</orgName><placeName><settlement type="city">Wageningue</settlement><region nuts="2">Gueldre (province)</region></placeName></affiliation></author><author><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation></author><author><name sortKey="Dhonukshe Rutten, Rosalie A M" sort="Dhonukshe Rutten, Rosalie A M" uniqKey="Dhonukshe Rutten R" first="Rosalie A M" last="Dhonukshe-Rutten">Rosalie A M. Dhonukshe-Rutten</name><affiliation wicri:level="4"><nlm:affiliation>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen</wicri:regionArea><orgName type="university">Université de Wageningue</orgName><placeName><settlement type="city">Wageningue</settlement><region nuts="2">Gueldre (province)</region></placeName></affiliation></author><author><name sortKey="Enneman, Anke W" sort="Enneman, Anke W" uniqKey="Enneman A" first="Anke W" last="Enneman">Anke W. Enneman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Evans, Daniel S" sort="Evans, Daniel S" uniqKey="Evans D" first="Daniel S" last="Evans">Daniel S. Evans</name><affiliation wicri:level="1"><nlm:affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Pacific Medical Center Research Institute, San Francisco, California 94107</wicri:regionArea><wicri:noRegion>California 94107</wicri:noRegion></affiliation></author><author><name sortKey="Forsen, Tom" sort="Forsen, Tom" uniqKey="Forsen T" first="Tom" last="Forsen">Tom Forsen</name><affiliation wicri:level="4"><nlm:affiliation>Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Friedrich, Nele" sort="Friedrich, Nele" uniqKey="Friedrich N" first="Nele" last="Friedrich">Nele Friedrich</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Fumeron, Frederic" sort="Fumeron, Frederic" uniqKey="Fumeron F" first="Frédéric" last="Fumeron">Frédéric Fumeron</name><affiliation wicri:level="1"><nlm:affiliation>INSERM, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris</wicri:regionArea><wicri:noRegion>75006 Paris</wicri:noRegion><wicri:noRegion>75006 Paris</wicri:noRegion></affiliation></author><author><name sortKey="Garcia, Melissa E" sort="Garcia, Melissa E" uniqKey="Garcia M" first="Melissa E" last="Garcia">Melissa E. Garcia</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="G Rtner, Simone" sort="G Rtner, Simone" uniqKey="G Rtner S" first="Simone" last="G Rtner">Simone G Rtner</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine A, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Han, Bok Ghee" sort="Han, Bok Ghee" uniqKey="Han B" first="Bok-Ghee" last="Han">Bok-Ghee Han</name><affiliation wicri:level="1"><nlm:affiliation>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914</wicri:regionArea><wicri:noRegion>Chungcheongbuk-do 370914</wicri:noRegion></affiliation></author><author><name sortKey="Havulinna, Aki S" sort="Havulinna, Aki S" uniqKey="Havulinna A" first="Aki S" last="Havulinna">Aki S. Havulinna</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Hernandez, Dena" sort="Hernandez, Dena" uniqKey="Hernandez D" first="Dena" last="Hernandez">Dena Hernandez</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Hillege, Hans" sort="Hillege, Hans" uniqKey="Hillege H" first="Hans" last="Hillege">Hans Hillege</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Ittermann, Till" sort="Ittermann, Till" uniqKey="Ittermann T" first="Till" last="Ittermann">Till Ittermann</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Kent, Jack W" sort="Kent, Jack W" uniqKey="Kent J" first="Jack W" last="Kent">Jack W. Kent</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245</wicri:regionArea><wicri:noRegion>Texas 78245</wicri:noRegion></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split 21000</wicri:regionArea><wicri:noRegion>Split 21000</wicri:noRegion></affiliation></author><author><name sortKey="Laatikainen, Tiina" sort="Laatikainen, Tiina" uniqKey="Laatikainen T" first="Tiina" last="Laatikainen">Tiina Laatikainen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name><affiliation wicri:level="1"><nlm:affiliation>Folkhälsan Research Centre, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Folkhälsan Research Centre, FI-00290 Helsinki</wicri:regionArea><wicri:noRegion>FI-00290 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Mateo Leach, Irene" sort="Mateo Leach, Irene" uniqKey="Mateo Leach I" first="Irene" last="Mateo Leach">Irene Mateo Leach</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Lee, Christine G" sort="Lee, Christine G" uniqKey="Lee C" first="Christine G" last="Lee">Christine G. Lee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Oregon Health and Science University, Portland, Oregon 97239</wicri:regionArea><wicri:noRegion>Oregon 97239</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Jong Young" sort="Lee, Jong Young" uniqKey="Lee J" first="Jong-Young" last="Lee">Jong-Young Lee</name><affiliation wicri:level="1"><nlm:affiliation>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914</wicri:regionArea><wicri:noRegion>Chungcheongbuk-do 370914</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Tian" sort="Liu, Tian" uniqKey="Liu T" first="Tian" last="Liu">Tian Liu</name><affiliation wicri:level="3"><nlm:affiliation>Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, 14195 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, 14195 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Youfang" sort="Liu, Youfang" uniqKey="Liu Y" first="Youfang" last="Liu">Youfang Liu</name><affiliation wicri:level="4"><nlm:affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280</wicri:regionArea><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName><placeName><settlement type="city">Chapel Hill (Caroline du Nord)</settlement><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Loh, Marie" sort="Loh, Marie" uniqKey="Loh M" first="Marie" last="Loh">Marie Loh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Lyytik Inen, Leo Pekka" sort="Lyytik Inen, Leo Pekka" uniqKey="Lyytik Inen L" first="Leo-Pekka" last="Lyytik Inen">Leo-Pekka Lyytik Inen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere</wicri:regionArea><wicri:noRegion>FI-33014 Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Medina Gomez, Carolina" sort="Medina Gomez, Carolina" uniqKey="Medina Gomez C" first="Carolina" last="Medina-Gomez">Carolina Medina-Gomez</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Michaelsson, Karl" sort="Michaelsson, Karl" uniqKey="Michaelsson K" first="Karl" last="Michaëlsson">Karl Michaëlsson</name><affiliation wicri:level="4"><nlm:affiliation>Department of Surgical Sciences, Orthopedics, Uppsala University, 751 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Surgical Sciences, Orthopedics, Uppsala University, 751 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Nalls, Mike A" sort="Nalls, Mike A" uniqKey="Nalls M" first="Mike A" last="Nalls">Mike A. Nalls</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Nielson, Carrie M" sort="Nielson, Carrie M" uniqKey="Nielson C" first="Carrie M" last="Nielson">Carrie M. Nielson</name><affiliation wicri:level="4"><nlm:affiliation>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239</wicri:regionArea><orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName><placeName><settlement type="city">Portland</settlement><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Oozageer, Laticia" sort="Oozageer, Laticia" uniqKey="Oozageer L" first="Laticia" last="Oozageer">Laticia Oozageer</name><affiliation wicri:level="1"><nlm:affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex UB1 3HW</wicri:regionArea><wicri:noRegion>Middlesex UB1 3HW</wicri:noRegion></affiliation></author><author><name sortKey="Pascoe, Laura" sort="Pascoe, Laura" uniqKey="Pascoe L" first="Laura" last="Pascoe">Laura Pascoe</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cell &Molecular Biosciences, Newcastle University, Newcastle NE1 7RU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cell &Molecular Biosciences, Newcastle University, Newcastle NE1 7RU</wicri:regionArea><wicri:noRegion>Newcastle NE1 7RU</wicri:noRegion></affiliation></author><author><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name><affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</nlm:affiliation><wicri:noCountry code="subField">UKnited</wicri:noCountry></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split 21000</wicri:regionArea><wicri:noRegion>Split 21000</wicri:noRegion></affiliation></author><author><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Sarzynski, Mark A" sort="Sarzynski, Mark A" uniqKey="Sarzynski M" first="Mark A" last="Sarzynski">Mark A. Sarzynski</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808</wicri:regionArea><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Shin, Chan Soo" sort="Shin, Chan Soo" uniqKey="Shin C" first="Chan Soo" last="Shin">Chan Soo Shin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Naran I, Nina Smolej" sort="Naran I, Nina Smolej" uniqKey="Naran I N" first="Nina Smolej" last="Naran I">Nina Smolej Naran I</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Anthropological Research, Zagreb 10000, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Institute for Anthropological Research, Zagreb 10000</wicri:regionArea><wicri:noRegion>Zagreb 10000</wicri:noRegion></affiliation></author><author><name sortKey="Spira, Dominik" sort="Spira, Dominik" uniqKey="Spira D" first="Dominik" last="Spira">Dominik Spira</name><affiliation wicri:level="3"><nlm:affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Srikanth, Priya" sort="Srikanth, Priya" uniqKey="Srikanth P" first="Priya" last="Srikanth">Priya Srikanth</name><affiliation wicri:level="4"><nlm:affiliation>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239</wicri:regionArea><orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName><placeName><settlement type="city">Portland</settlement><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Steinhagen Thiessen, Elisabeth" sort="Steinhagen Thiessen, Elisabeth" uniqKey="Steinhagen Thiessen E" first="Elisabeth" last="Steinhagen-Thiessen">Elisabeth Steinhagen-Thiessen</name><affiliation wicri:level="3"><nlm:affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Sung, Yun Ju" sort="Sung, Yun Ju" uniqKey="Sung Y" first="Yun Ju" last="Sung">Yun Ju Sung</name><affiliation wicri:level="4"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Swart, Karin M A" sort="Swart, Karin M A" uniqKey="Swart K" first="Karin M A" last="Swart">Karin M A. Swart</name><affiliation wicri:level="1"><nlm:affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam</wicri:regionArea><wicri:noRegion>1081 BT Amsterdam</wicri:noRegion></affiliation></author><author><name sortKey="Taittonen, Leena" sort="Taittonen, Leena" uniqKey="Taittonen L" first="Leena" last="Taittonen">Leena Taittonen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Oulu, FI-90014 Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Pediatrics, University of Oulu, FI-90014 Oulu</wicri:regionArea><wicri:noRegion>FI-90014 Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="1"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225</wicri:regionArea><wicri:noRegion>Maryland 21225</wicri:noRegion></affiliation></author><author><name sortKey="Tikkanen, Emmi" sort="Tikkanen, Emmi" uniqKey="Tikkanen E" first="Emmi" last="Tikkanen">Emmi Tikkanen</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Van Der Velde, Nathalie" sort="Van Der Velde, Nathalie" uniqKey="Van Der Velde N" first="Nathalie" last="Van Der Velde">Nathalie Van Der Velde</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Schoor, Natasja M" sort="Van Schoor, Natasja M" uniqKey="Van Schoor N" first="Natasja M" last="Van Schoor">Natasja M. Van Schoor</name><affiliation wicri:level="1"><nlm:affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam</wicri:regionArea><wicri:noRegion>1081 BT Amsterdam</wicri:noRegion></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612</wicri:regionArea><wicri:noRegion>Illinois 60612</wicri:noRegion></affiliation></author><author><name sortKey="Zmuda, Joseph M" sort="Zmuda, Joseph M" uniqKey="Zmuda J" first="Joseph M" last="Zmuda">Joseph M. Zmuda</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology; University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology; University of Pittsburgh, Pittsburgh, Pennsylvania 15261</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Eklund, Niina" sort="Eklund, Niina" uniqKey="Eklund N" first="Niina" last="Eklund">Niina Eklund</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Forrester, Terrence" sort="Forrester, Terrence" uniqKey="Forrester T" first="Terrence" last="Forrester">Terrence Forrester</name><affiliation wicri:level="1"><nlm:affiliation>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica.</nlm:affiliation><country xml:lang="fr">Jamaïque</country><wicri:regionArea>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15</wicri:regionArea><wicri:noRegion>Mona JMAAW15</wicri:noRegion></affiliation></author><author><name sortKey="Grarup, Niels" sort="Grarup, Niels" uniqKey="Grarup N" first="Niels" last="Grarup">Niels Grarup</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Kristiansson, Kati" sort="Kristiansson, Kati" uniqKey="Kristiansson K" first="Kati" last="Kristiansson">Kati Kristiansson</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Kuulasmaa, Teemu" sort="Kuulasmaa, Teemu" uniqKey="Kuulasmaa T" first="Teemu" last="Kuulasmaa">Teemu Kuulasmaa</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio</wicri:regionArea><wicri:noRegion>70210 Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio</wicri:regionArea><wicri:noRegion>70210 Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Palmer, Cameron D" sort="Palmer, Cameron D" uniqKey="Palmer C" first="Cameron D" last="Palmer">Cameron D. Palmer</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142</wicri:regionArea><wicri:noRegion>Cambridge 2142</wicri:noRegion></affiliation></author><author><name sortKey="Ried, Janina S" sort="Ried, Janina S" uniqKey="Ried J" first="Janina S" last="Ried">Janina S. Ried</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A" last="Scott">Robert A. Scott</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Stancakova, Alena" sort="Stancakova, Alena" uniqKey="Stancakova A" first="Alena" last="Stancáková">Alena Stancáková</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio</wicri:regionArea><wicri:noRegion>70210 Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Wagner, Peter J" sort="Wagner, Peter J" uniqKey="Wagner P" first="Peter J" last="Wagner">Peter J. Wagner</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Demirkan, Ayse" sort="Demirkan, Ayse" uniqKey="Demirkan A" first="Ayse" last="Demirkan">Ayse Demirkan</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Doring, Angela" sort="Doring, Angela" uniqKey="Doring A" first="Angela" last="Döring">Angela Döring</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur 201, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur 201</wicri:regionArea><wicri:noRegion>Kopavogur 201</wicri:noRegion></affiliation></author><author><name sortKey="Kiel, Douglas P" sort="Kiel, Douglas P" uniqKey="Kiel D" first="Douglas P" last="Kiel">Douglas P. Kiel</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Kuhnel, Brigitte" sort="Kuhnel, Brigitte" uniqKey="Kuhnel B" first="Brigitte" last="Kühnel">Brigitte Kühnel</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation wicri:level="4"><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101</wicri:regionArea><orgName type="university">Université de Washington</orgName><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R" last="O'Connell">Jeffrey R. O'Connell</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201</wicri:regionArea><wicri:noRegion>Maryland 21201</wicri:noRegion></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201</wicri:regionArea><wicri:noRegion>Maryland 21201</wicri:noRegion></affiliation></author><author><name sortKey="Song, Kijoung" sort="Song, Kijoung" uniqKey="Song K" first="Kijoung" last="Song">Kijoung Song</name><affiliation wicri:level="1"><nlm:affiliation>Genetics, Projects Clinical Platforms and Sciences, GlaxoSmithKline, Philadelphia, Pennsylvania 19112, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Genetics, Projects Clinical Platforms and Sciences, GlaxoSmithKline, Philadelphia, Pennsylvania 19112</wicri:regionArea><wicri:noRegion>Pennsylvania 19112</wicri:noRegion></affiliation></author><author><name sortKey="Vandenput, Liesbeth" sort="Vandenput, Liesbeth" uniqKey="Vandenput L" first="Liesbeth" last="Vandenput">Liesbeth Vandenput</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg</wicri:regionArea><wicri:noRegion>413 45 Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</nlm:affiliation><wicri:noCountry code="subField">Rotterdam The Netherlands</wicri:noCountry></affiliation></author><author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="White, Charles C" sort="White, Charles C" uniqKey="White C" first="Charles C" last="White">Charles C. White</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Boettcher, Yvonne" sort="Boettcher, Yvonne" uniqKey="Boettcher Y" first="Yvonne" last="Boettcher">Yvonne Boettcher</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Cooper, Richard S" sort="Cooper, Richard S" uniqKey="Cooper R" first="Richard S" last="Cooper">Richard S. Cooper</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053</wicri:regionArea><wicri:noRegion>Illinois 61053</wicri:noRegion></affiliation></author><author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G" last="Forouhi">Nita G. Forouhi</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Hingorani, Aroon" sort="Hingorani, Aroon" uniqKey="Hingorani A" first="Aroon" last="Hingorani">Aroon Hingorani</name><affiliation wicri:level="4"><nlm:affiliation>Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cardiovascular Science, University College London, London WC1E 6BT</wicri:regionArea><orgName type="university">University College de Londres</orgName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="J Rgensen, Torben" sort="J Rgensen, Torben" uniqKey="J Rgensen T" first="Torben" last="J Rgensen">Torben J Rgensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Jousilahti, Pekka" sort="Jousilahti, Pekka" uniqKey="Jousilahti P" first="Pekka" last="Jousilahti">Pekka Jousilahti</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, UCL, London WC1E 6BT</wicri:regionArea><wicri:noRegion>London WC1E 6BT</wicri:noRegion></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, UCL, London WC1E 6BT</wicri:regionArea><wicri:noRegion>London WC1E 6BT</wicri:noRegion></affiliation></author><author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio</wicri:regionArea><wicri:noRegion>70210 Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Linneberg, Allan" sort="Linneberg, Allan" uniqKey="Linneberg A" first="Allan" last="Linneberg">Allan Linneberg</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup</wicri:regionArea><wicri:noRegion>2600 Glostrup</wicri:noRegion></affiliation></author><author><name sortKey="Luke, Amy" sort="Luke, Amy" uniqKey="Luke A" first="Amy" last="Luke">Amy Luke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053</wicri:regionArea><wicri:noRegion>Illinois 61053</wicri:noRegion></affiliation></author><author><name sortKey="Mckenzie, Colin A" sort="Mckenzie, Colin A" uniqKey="Mckenzie C" first="Colin A" last="Mckenzie">Colin A. Mckenzie</name><affiliation wicri:level="1"><nlm:affiliation>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica.</nlm:affiliation><country xml:lang="fr">Jamaïque</country><wicri:regionArea>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15</wicri:regionArea><wicri:noRegion>Mona JMAAW15</wicri:noRegion></affiliation></author><author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Pedersen, Oluf" sort="Pedersen, Oluf" uniqKey="Pedersen O" first="Oluf" last="Pedersen">Oluf Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Tayo, Bamidele O" sort="Tayo, Bamidele O" uniqKey="Tayo B" first="Bamidele O" last="Tayo">Bamidele O. Tayo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053</wicri:regionArea><wicri:noRegion>Illinois 61053</wicri:noRegion></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612</wicri:regionArea><wicri:noRegion>Illinois 60612</wicri:noRegion></affiliation></author><author><name sortKey="Bertram, Lars" sort="Bertram, Lars" uniqKey="Bertram L" first="Lars" last="Bertram">Lars Bertram</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health, Faculty of Medicine, Imperial College London, London W6 8RP, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Public Health, Faculty of Medicine, Imperial College London, London W6 8RP</wicri:regionArea><wicri:noRegion>London W6 8RP</wicri:noRegion></affiliation></author><author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><affiliation wicri:level="2"><nlm:affiliation>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville</wicri:cityArea></affiliation></author><author><name sortKey="Bluher, Matthias" sort="Bluher, Matthias" uniqKey="Bluher M" first="Matthias" last="Blüher">Matthias Blüher</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808</wicri:regionArea><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Cho, Nam H" sort="Cho, Nam H" uniqKey="Cho N" first="Nam H" last="Cho">Nam H. Cho</name><affiliation wicri:level="1"><nlm:affiliation>Ajou University School of Medicine, Department of Preventive Medicine, Suwon Kyoung-gi 443-721, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Ajou University School of Medicine, Department of Preventive Medicine, Suwon Kyoung-gi 443-721</wicri:regionArea><wicri:noRegion>Suwon Kyoung-gi 443-721</wicri:noRegion></affiliation></author><author><name sortKey="Cummings, Steven R" sort="Cummings, Steven R" uniqKey="Cummings S" first="Steven R" last="Cummings">Steven R. Cummings</name><affiliation wicri:level="1"><nlm:affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Pacific Medical Center Research Institute, San Francisco, California 94107</wicri:regionArea><wicri:noRegion>California 94107</wicri:noRegion></affiliation></author><author><name sortKey="Czerwinski, Stefan A" sort="Czerwinski, Stefan A" uniqKey="Czerwinski S" first="Stefan A" last="Czerwinski">Stefan A. Czerwinski</name><affiliation wicri:level="1"><nlm:affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420</wicri:regionArea><wicri:noRegion>Ohio 45420</wicri:noRegion></affiliation></author><author><name sortKey="Demuth, Ilja" sort="Demuth, Ilja" uniqKey="Demuth I" first="Ilja" last="Demuth">Ilja Demuth</name><affiliation wicri:level="3"><nlm:affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Eckardt, Rahel" sort="Eckardt, Rahel" uniqKey="Eckardt R" first="Rahel" last="Eckardt">Rahel Eckardt</name><affiliation wicri:level="3"><nlm:affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="1"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225</wicri:regionArea><wicri:noRegion>Maryland 21225</wicri:noRegion></affiliation></author><author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H" last="Franco">Oscar H. Franco</name><affiliation><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</nlm:affiliation><wicri:noCountry code="subField">Rotterdam The Netherlands</wicri:noCountry></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T" last="Gansevoort">Ron T. Gansevoort</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Hastie, Nicholas" sort="Hastie, Nicholas" uniqKey="Hastie N" first="Nicholas" last="Hastie">Nicholas Hastie</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Heliovaara, Markku" sort="Heliovaara, Markku" uniqKey="Heliovaara M" first="Markku" last="Heliövaara">Markku Heliövaara</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</nlm:affiliation><wicri:noCountry code="subField">Rotterdam The Netherlands</wicri:noCountry></affiliation></author><author><name sortKey="Jordan, Joanne M" sort="Jordan, Joanne M" uniqKey="Jordan J" first="Joanne M" last="Jordan">Joanne M. Jordan</name><affiliation wicri:level="4"><nlm:affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280</wicri:regionArea><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName><placeName><settlement type="city">Chapel Hill (Caroline du Nord)</settlement><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Physiology, Tampere University Hospital, FI-33521 Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology, Tampere University Hospital, FI-33521 Tampere</wicri:regionArea><wicri:noRegion>FI-33521 Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Kajantie, Eero" sort="Kajantie, Eero" uniqKey="Kajantie E" first="Eero" last="Kajantie">Eero Kajantie</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Knekt, Paul B" sort="Knekt, Paul B" uniqKey="Knekt P" first="Paul B" last="Knekt">Paul B. Knekt</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Koskinen, Seppo" sort="Koskinen, Seppo" uniqKey="Koskinen S" first="Seppo" last="Koskinen">Seppo Koskinen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere</wicri:regionArea><wicri:noRegion>FI-33014 Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Sciences, Uppsala University, 751 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation wicri:level="1"><nlm:affiliation>Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157</wicri:regionArea><wicri:noRegion>North Carolina 27157</wicri:noRegion></affiliation></author><author><name sortKey="Orwoll, Eric S" sort="Orwoll, Eric S" uniqKey="Orwoll E" first="Eric S" last="Orwoll">Eric S. Orwoll</name><affiliation wicri:level="4"><nlm:affiliation>Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239</wicri:regionArea><orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName><placeName><settlement type="city">Portland</settlement><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Osmond, Clive" sort="Osmond, Clive" uniqKey="Osmond C" first="Clive" last="Osmond">Clive Osmond</name><affiliation wicri:level="1"><nlm:affiliation>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD</wicri:regionArea><wicri:noRegion>Southampton SO16 6YD</wicri:noRegion></affiliation></author><author><name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Perusse, Louis" sort="Perusse, Louis" uniqKey="Perusse L" first="Louis" last="Pérusse">Louis Pérusse</name><affiliation wicri:level="1"><nlm:affiliation>Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department of Kinesiology, Laval University, Québec City, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T" last="Raitakari">Olli T. Raitakari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku</wicri:regionArea><wicri:noRegion>FI-20521 Turku</wicri:noRegion></affiliation></author><author><name sortKey="Rankinen, Tuomo" sort="Rankinen, Tuomo" uniqKey="Rankinen T" first="Tuomo" last="Rankinen">Tuomo Rankinen</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808</wicri:regionArea><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Rao, D C" sort="Rao, D C" uniqKey="Rao D" first="D C" last="Rao">D C Rao</name><affiliation wicri:level="4"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Rice, Treva K" sort="Rice, Treva K" uniqKey="Rice T" first="Treva K" last="Rice">Treva K. Rice</name><affiliation wicri:level="4"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="S Rensen, Thorkild I A" sort="S Rensen, Thorkild I A" uniqKey="S Rensen T" first="Thorkild I A" last="S Rensen">Thorkild I A. S Rensen</name><affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</nlm:affiliation><wicri:noCountry code="subField">UKnited</wicri:noCountry></affiliation></author><author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, Department of Medicine, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, Department of Medicine, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Towne, Bradford" sort="Towne, Bradford" uniqKey="Towne B" first="Bradford" last="Towne">Bradford Towne</name><affiliation wicri:level="1"><nlm:affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420</wicri:regionArea><wicri:noRegion>Ohio 45420</wicri:noRegion></affiliation></author><author><name sortKey="Tranah, Gregory J" sort="Tranah, Gregory J" uniqKey="Tranah G" first="Gregory J" last="Tranah">Gregory J. Tranah</name><affiliation wicri:level="1"><nlm:affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Pacific Medical Center Research Institute, San Francisco, California 94107</wicri:regionArea><wicri:noRegion>California 94107</wicri:noRegion></affiliation></author><author><name sortKey="Tremblay, Angelo" sort="Tremblay, Angelo" uniqKey="Tremblay A" first="Angelo" last="Tremblay">Angelo Tremblay</name><affiliation wicri:level="1"><nlm:affiliation>Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department of Kinesiology, Laval University, Québec City, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Vartiainen, Erkki" sort="Vartiainen, Erkki" uniqKey="Vartiainen E" first="Erkki" last="Vartiainen">Erkki Vartiainen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Viikari, Jorma S" sort="Viikari, Jorma S" uniqKey="Viikari J" first="Jorma S" last="Viikari">Jorma S. Viikari</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, University of Turku, FI-20521 Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Turku, FI-20521 Turku</wicri:regionArea><orgName type="university">Université de Turku</orgName><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Vohl, Marie Claude" sort="Vohl, Marie Claude" uniqKey="Vohl M" first="Marie-Claude" last="Vohl">Marie-Claude Vohl</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada G1V 0A6.</nlm:affiliation><country>Canada</country><wicri:regionArea>Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Walker, Mark" sort="Walker, Mark" uniqKey="Walker M" first="Mark" last="Walker">Mark Walker</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation></author><author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Wild, Sarah" sort="Wild, Sarah" uniqKey="Wild S" first="Sarah" last="Wild">Sarah Wild</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loïc" last="Yengo">Loïc Yengo</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Bishop, D Timothy" sort="Bishop, D Timothy" uniqKey="Bishop D" first="D Timothy" last="Bishop">D Timothy Bishop</name><affiliation wicri:level="4"><nlm:affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B" last="Borecki">Ingrid B. Borecki</name><affiliation wicri:level="4"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Cupples, L Adrienne" sort="Cupples, L Adrienne" uniqKey="Cupples L" first="L Adrienne" last="Cupples">L Adrienne Cupples</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation></author><author><name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, 3000CA Rotterdam/Zuidholland, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, 3000CA Rotterdam/Zuidholland</wicri:regionArea><wicri:noRegion>3000CA Rotterdam/Zuidholland</wicri:noRegion></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation wicri:level="4"><nlm:affiliation>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ</wicri:regionArea><orgName type="university">Université de Londres</orgName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fatemifar, Ghazaleh" sort="Fatemifar, Ghazaleh" uniqKey="Fatemifar G" first="Ghazaleh" last="Fatemifar">Ghazaleh Fatemifar</name><affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</nlm:affiliation><wicri:noCountry code="subField">UKnited</wicri:noCountry></affiliation></author><author><name sortKey="Fox, Caroline" sort="Fox, Caroline" uniqKey="Fox C" first="Caroline" last="Fox">Caroline Fox</name><affiliation wicri:level="1"><nlm:affiliation>Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts 02115</wicri:regionArea><wicri:noRegion>Massachusetts 02115</wicri:noRegion></affiliation></author><author><name sortKey="Furey, Terrence S" sort="Furey, Terrence S" uniqKey="Furey T" first="Terrence S" last="Furey">Terrence S. Furey</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599</wicri:regionArea><wicri:noRegion>North Carolina 27599</wicri:noRegion></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Han, Jiali" sort="Han, Jiali" uniqKey="Han J" first="Jiali" last="Han">Jiali Han</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202</wicri:regionArea><wicri:noRegion>Indiana 46202</wicri:noRegion></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142</wicri:regionArea><wicri:noRegion>Cambridge 2142</wicri:noRegion></affiliation></author><author><name sortKey="Karjalainen, Juha" sort="Karjalainen, Juha" uniqKey="Karjalainen J" first="Juha" last="Karjalainen">Juha Karjalainen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen</wicri:regionArea><wicri:noRegion>9700 RB Groningen</wicri:noRegion></affiliation></author><author><name sortKey="Karpe, Fredrik" sort="Karpe, Fredrik" uniqKey="Karpe F" first="Fredrik" last="Karpe">Fredrik Karpe</name><affiliation wicri:level="4"><nlm:affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Kaplan, Robert C" sort="Kaplan, Robert C" uniqKey="Kaplan R" first="Robert C" last="Kaplan">Robert C. Kaplan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461</wicri:regionArea><wicri:noRegion>New York 10461</wicri:noRegion></affiliation></author><author><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><affiliation wicri:level="1"><nlm:affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex UB1 3HW</wicri:regionArea><wicri:noRegion>Middlesex UB1 3HW</wicri:noRegion></affiliation></author><author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Murabito, Joanne M" sort="Murabito, Joanne M" uniqKey="Murabito J" first="Joanne M" last="Murabito">Joanne M. Murabito</name><affiliation wicri:level="1"><nlm:affiliation>Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, Massachusetts 02118, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation></author><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P" last="Morris">Andrew P. Morris</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Bishop, Julia A N" sort="Bishop, Julia A N" uniqKey="Bishop J" first="Julia A N" last="Bishop">Julia A N. Bishop</name><affiliation wicri:level="4"><nlm:affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name><affiliation wicri:level="4"><nlm:affiliation>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7400</wicri:regionArea><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName><placeName><settlement type="city">Chapel Hill (Caroline du Nord)</settlement><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Ohlsson, Claes" sort="Ohlsson, Claes" uniqKey="Ohlsson C" first="Claes" last="Ohlsson">Claes Ohlsson</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg</wicri:regionArea><wicri:noRegion>413 45 Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K" last="Ong">Ken K. Ong</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Richards, J Brent" sort="Richards, J Brent" uniqKey="Richards J" first="J Brent" last="Richards">J Brent Richards</name><affiliation wicri:level="4"><nlm:affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Schadt, Eric E" sort="Schadt, Eric E" uniqKey="Schadt E" first="Eric E" last="Schadt">Eric E. Schadt</name><affiliation wicri:level="1"><nlm:affiliation>Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029</wicri:regionArea><wicri:noRegion>New York 10029</wicri:noRegion></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Widen, Elisabeth" sort="Widen, Elisabeth" uniqKey="Widen E" first="Elisabeth" last="Widén">Elisabeth Widén</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Willer, Cristen J" sort="Willer, Cristen J" uniqKey="Willer C" first="Cristen J" last="Willer">Cristen J. Willer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Jian" sort="Yang, Jian" uniqKey="Yang J" first="Jian" last="Yang">Jian Yang</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, The University of Queensland, Brisbane 4072</wicri:regionArea><wicri:noRegion>Brisbane 4072</wicri:noRegion></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation wicri:level="4"><nlm:affiliation>Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, 750 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L" last="Mohlke">Karen L. Mohlke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599</wicri:regionArea><wicri:noRegion>North Carolina 27599</wicri:noRegion></affiliation></author><author><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N" last="Hirschhorn">Joel N. Hirschhorn</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142</wicri:regionArea><wicri:noRegion>Cambridge 2142</wicri:noRegion></affiliation></author><author><name sortKey="Pospisilik, John Andrew" sort="Pospisilik, John Andrew" uniqKey="Pospisilik J" first="John Andrew" last="Pospisilik">John Andrew Pospisilik</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epigenetics, Max Planck Institute of Immunobiology and Epigenetics, D-76108 Freiburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Epigenetics, Max Planck Institute of Immunobiology and Epigenetics, D-76108 Freiburg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Zillikens, M Carola" sort="Zillikens, M Carola" uniqKey="Zillikens M" first="M Carola" last="Zillikens">M Carola Zillikens</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Lindgren, Cecilia" sort="Lindgren, Cecilia" uniqKey="Lindgren C" first="Cecilia" last="Lindgren">Cecilia Lindgren</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Kilpel Inen, Tuomas Oskari" sort="Kilpel Inen, Tuomas Oskari" uniqKey="Kilpel Inen T" first="Tuomas Oskari" last="Kilpel Inen">Tuomas Oskari Kilpel Inen</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029</wicri:regionArea><wicri:noRegion>New York 10029</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26833246</idno><idno type="pmid">26833246</idno><idno type="doi">10.1038/ncomms10495</idno><idno type="wicri:Area/PubMed/Corpus">002296</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002296</idno><idno type="wicri:Area/PubMed/Curation">002270</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002270</idno><idno type="wicri:Area/PubMed/Checkpoint">002270</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002270</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.</title><author><name sortKey="Lu, Yingchang" sort="Lu, Yingchang" uniqKey="Lu Y" first="Yingchang" last="Lu">Yingchang Lu</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029</wicri:regionArea><wicri:noRegion>New York 10029</wicri:noRegion></affiliation></author><author><name sortKey="Day, Felix R" sort="Day, Felix R" uniqKey="Day F" first="Felix R" last="Day">Felix R. Day</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Gustafsson, Stefan" sort="Gustafsson, Stefan" uniqKey="Gustafsson S" first="Stefan" last="Gustafsson">Stefan Gustafsson</name><affiliation wicri:level="4"><nlm:affiliation>Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, 750 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Buchkovich, Martin L" sort="Buchkovich, Martin L" uniqKey="Buchkovich M" first="Martin L" last="Buchkovich">Martin L. Buchkovich</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599</wicri:regionArea><wicri:noRegion>North Carolina 27599</wicri:noRegion></affiliation></author><author><name sortKey="Na, Jianbo" sort="Na, Jianbo" uniqKey="Na J" first="Jianbo" last="Na">Jianbo Na</name><affiliation wicri:level="1"><nlm:affiliation>Department of Developmental and Regenerative Biology, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Developmental and Regenerative Biology, The Icahn School of Medicine at Mount Sinai, New York, New York 10029</wicri:regionArea><wicri:noRegion>New York 10029</wicri:noRegion></affiliation></author><author><name sortKey="Bataille, Veronique" sort="Bataille, Veronique" uniqKey="Bataille V" first="Veronique" last="Bataille">Veronique Bataille</name><affiliation wicri:level="1"><nlm:affiliation>West Herts NHS Trust, Herts HP2 4AD, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>West Herts NHS Trust, Herts HP2 4AD</wicri:regionArea><wicri:noRegion>Herts HP2 4AD</wicri:noRegion></affiliation></author><author><name sortKey="Cousminer, Diana L" sort="Cousminer, Diana L" uniqKey="Cousminer D" first="Diana L" last="Cousminer">Diana L. Cousminer</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Dastani, Zari" sort="Dastani, Zari" uniqKey="Dastani Z" first="Zari" last="Dastani">Zari Dastani</name><affiliation wicri:level="4"><nlm:affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Drong, Alexander W" sort="Drong, Alexander W" uniqKey="Drong A" first="Alexander W" last="Drong">Alexander W. Drong</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, Univeristy of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Evans, David M" sort="Evans, David M" uniqKey="Evans D" first="David M" last="Evans">David M. Evans</name><affiliation wicri:level="1"><nlm:affiliation>University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland 4102, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland 4102</wicri:regionArea><wicri:noRegion>Queensland 4102</wicri:noRegion></affiliation></author><author><name sortKey="Falchi, Mario" sort="Falchi, Mario" uniqKey="Falchi M" first="Mario" last="Falchi">Mario Falchi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F" last="Feitosa">Mary F. Feitosa</name><affiliation wicri:level="4"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Hedman, Sa K" sort="Hedman, Sa K" uniqKey="Hedman " first=" Sa K" last="Hedman"> Sa K. Hedman</name><affiliation wicri:level="4"><nlm:affiliation>Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, 750 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Haring, Robin" sort="Haring, Robin" uniqKey="Haring R" first="Robin" last="Haring">Robin Haring</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Iles, Mark M" sort="Iles, Mark M" uniqKey="Iles M" first="Mark M" last="Iles">Mark M. Iles</name><affiliation wicri:level="4"><nlm:affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="Justice, Anne E" sort="Justice, Anne E" uniqKey="Justice A" first="Anne E" last="Justice">Anne E. Justice</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599</wicri:regionArea><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName><placeName><settlement type="city">Chapel Hill (Caroline du Nord)</settlement><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><affiliation wicri:level="4"><nlm:affiliation>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ</wicri:regionArea><orgName type="university">Université de Londres</orgName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Li, Rui" sort="Li, Rui" uniqKey="Li R" first="Rui" last="Li">Rui Li</name><affiliation wicri:level="4"><nlm:affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Li, Xin" sort="Li, Xin" uniqKey="Li X" first="Xin" last="Li">Xin Li</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115</wicri:regionArea><wicri:noRegion>Massachusetts 02115</wicri:noRegion></affiliation></author><author><name sortKey="Locke, Adam" sort="Locke, Adam" uniqKey="Locke A" first="Adam" last="Locke">Adam Locke</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Chen" sort="Lu, Chen" uniqKey="Lu C" first="Chen" last="Lu">Chen Lu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R B" last="Perry">John R B. Perry</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H" last="Pers">Tune H. Pers</name><affiliation wicri:level="1"><nlm:affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115</wicri:regionArea><wicri:noRegion>Massachusetts 02115</wicri:noRegion></affiliation></author><author><name sortKey="Qi, Qibin" sort="Qi, Qibin" uniqKey="Qi Q" first="Qibin" last="Qi">Qibin Qi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461</wicri:regionArea><wicri:noRegion>New York 10461</wicri:noRegion></affiliation></author><author><name sortKey="Sanna, Marianna" sort="Sanna, Marianna" uniqKey="Sanna M" first="Marianna" last="Sanna">Marianna Sanna</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Schmidt, Ellen M" sort="Schmidt, Ellen M" uniqKey="Schmidt E" first="Ellen M" last="Schmidt">Ellen M. Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Scott, William R" sort="Scott, William R" uniqKey="Scott W" first="William R" last="Scott">William R. Scott</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Shungin, Dmitry" sort="Shungin, Dmitry" uniqKey="Shungin D" first="Dmitry" last="Shungin">Dmitry Shungin</name><affiliation wicri:level="1"><nlm:affiliation>Lund University Diabetes Centre, Department of Clinical Science, Genetic and Molecular Epidemiology Unit, Skåne University Hosptial, 205 02 Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science, Genetic and Molecular Epidemiology Unit, Skåne University Hosptial, 205 02 Malmö</wicri:regionArea><wicri:noRegion>205 02 Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Vinkhuyzen, Anna A E" sort="Vinkhuyzen, Anna A E" uniqKey="Vinkhuyzen A" first="Anna A E" last="Vinkhuyzen">Anna A E. Vinkhuyzen</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, The University of Queensland, Brisbane 4072</wicri:regionArea><wicri:noRegion>Brisbane 4072</wicri:noRegion></affiliation></author><author><name sortKey="Walker, Ryan W" sort="Walker, Ryan W" uniqKey="Walker R" first="Ryan W" last="Walker">Ryan W. Walker</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029</wicri:regionArea><wicri:noRegion>New York 10029</wicri:noRegion></affiliation></author><author><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Mingfeng" sort="Zhang, Mingfeng" uniqKey="Zhang M" first="Mingfeng" last="Zhang">Mingfeng Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts 02115</wicri:regionArea><wicri:noRegion>Massachusetts 02115</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Zhu, Zhihong" sort="Zhu, Zhihong" uniqKey="Zhu Z" first="Zhihong" last="Zhu">Zhihong Zhu</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, The University of Queensland, Brisbane 4072</wicri:regionArea><wicri:noRegion>Brisbane 4072</wicri:noRegion></affiliation></author><author><name sortKey="Afzal, Uzma" sort="Afzal, Uzma" uniqKey="Afzal U" first="Uzma" last="Afzal">Uzma Afzal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Ahluwalia, Tarunveer Singh" sort="Ahluwalia, Tarunveer Singh" uniqKey="Ahluwalia T" first="Tarunveer Singh" last="Ahluwalia">Tarunveer Singh Ahluwalia</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Bakker, Stephan J L" sort="Bakker, Stephan J L" uniqKey="Bakker S" first="Stephan J L" last="Bakker">Stephan J L. Bakker</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245</wicri:regionArea><wicri:noRegion>Texas 78245</wicri:noRegion></affiliation></author><author><name sortKey="Bonnefond, Amelie" sort="Bonnefond, Amelie" uniqKey="Bonnefond A" first="Amélie" last="Bonnefond">Amélie Bonnefond</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Borodulin, Katja" sort="Borodulin, Katja" uniqKey="Borodulin K" first="Katja" last="Borodulin">Katja Borodulin</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Buchman, Aron S" sort="Buchman, Aron S" uniqKey="Buchman A" first="Aron S" last="Buchman">Aron S. Buchman</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612</wicri:regionArea><wicri:noRegion>Illinois 60612</wicri:noRegion></affiliation></author><author><name sortKey="Cederholm, Tommy" sort="Cederholm, Tommy" uniqKey="Cederholm T" first="Tommy" last="Cederholm">Tommy Cederholm</name><affiliation wicri:level="4"><nlm:affiliation>Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 751 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 751 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Choh, Audrey C" sort="Choh, Audrey C" uniqKey="Choh A" first="Audrey C" last="Choh">Audrey C. Choh</name><affiliation wicri:level="1"><nlm:affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420</wicri:regionArea><wicri:noRegion>Ohio 45420</wicri:noRegion></affiliation></author><author><name sortKey="Choi, Hyung Jin" sort="Choi, Hyung Jin" uniqKey="Choi H" first="Hyung Jin" last="Choi">Hyung Jin Choi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Anatomy, Seoul National University College of Medicine, Seoul 03080, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Anatomy, Seoul National University College of Medicine, Seoul 03080</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Curran, Joanne E" sort="Curran, Joanne E" uniqKey="Curran J" first="Joanne E" last="Curran">Joanne E. Curran</name><affiliation wicri:level="2"><nlm:affiliation>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville</wicri:cityArea></affiliation></author><author><name sortKey="De Groot, Lisette C P G M" sort="De Groot, Lisette C P G M" uniqKey="De Groot L" first="Lisette C P G M" last="De Groot">Lisette C P G M. De Groot</name><affiliation wicri:level="4"><nlm:affiliation>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen</wicri:regionArea><orgName type="university">Université de Wageningue</orgName><placeName><settlement type="city">Wageningue</settlement><region nuts="2">Gueldre (province)</region></placeName></affiliation></author><author><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation></author><author><name sortKey="Dhonukshe Rutten, Rosalie A M" sort="Dhonukshe Rutten, Rosalie A M" uniqKey="Dhonukshe Rutten R" first="Rosalie A M" last="Dhonukshe-Rutten">Rosalie A M. Dhonukshe-Rutten</name><affiliation wicri:level="4"><nlm:affiliation>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen</wicri:regionArea><orgName type="university">Université de Wageningue</orgName><placeName><settlement type="city">Wageningue</settlement><region nuts="2">Gueldre (province)</region></placeName></affiliation></author><author><name sortKey="Enneman, Anke W" sort="Enneman, Anke W" uniqKey="Enneman A" first="Anke W" last="Enneman">Anke W. Enneman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Evans, Daniel S" sort="Evans, Daniel S" uniqKey="Evans D" first="Daniel S" last="Evans">Daniel S. Evans</name><affiliation wicri:level="1"><nlm:affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Pacific Medical Center Research Institute, San Francisco, California 94107</wicri:regionArea><wicri:noRegion>California 94107</wicri:noRegion></affiliation></author><author><name sortKey="Forsen, Tom" sort="Forsen, Tom" uniqKey="Forsen T" first="Tom" last="Forsen">Tom Forsen</name><affiliation wicri:level="4"><nlm:affiliation>Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Friedrich, Nele" sort="Friedrich, Nele" uniqKey="Friedrich N" first="Nele" last="Friedrich">Nele Friedrich</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Fumeron, Frederic" sort="Fumeron, Frederic" uniqKey="Fumeron F" first="Frédéric" last="Fumeron">Frédéric Fumeron</name><affiliation wicri:level="1"><nlm:affiliation>INSERM, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris</wicri:regionArea><wicri:noRegion>75006 Paris</wicri:noRegion><wicri:noRegion>75006 Paris</wicri:noRegion></affiliation></author><author><name sortKey="Garcia, Melissa E" sort="Garcia, Melissa E" uniqKey="Garcia M" first="Melissa E" last="Garcia">Melissa E. Garcia</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="G Rtner, Simone" sort="G Rtner, Simone" uniqKey="G Rtner S" first="Simone" last="G Rtner">Simone G Rtner</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine A, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Han, Bok Ghee" sort="Han, Bok Ghee" uniqKey="Han B" first="Bok-Ghee" last="Han">Bok-Ghee Han</name><affiliation wicri:level="1"><nlm:affiliation>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914</wicri:regionArea><wicri:noRegion>Chungcheongbuk-do 370914</wicri:noRegion></affiliation></author><author><name sortKey="Havulinna, Aki S" sort="Havulinna, Aki S" uniqKey="Havulinna A" first="Aki S" last="Havulinna">Aki S. Havulinna</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Hernandez, Dena" sort="Hernandez, Dena" uniqKey="Hernandez D" first="Dena" last="Hernandez">Dena Hernandez</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Hillege, Hans" sort="Hillege, Hans" uniqKey="Hillege H" first="Hans" last="Hillege">Hans Hillege</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Ittermann, Till" sort="Ittermann, Till" uniqKey="Ittermann T" first="Till" last="Ittermann">Till Ittermann</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Kent, Jack W" sort="Kent, Jack W" uniqKey="Kent J" first="Jack W" last="Kent">Jack W. Kent</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245</wicri:regionArea><wicri:noRegion>Texas 78245</wicri:noRegion></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split 21000</wicri:regionArea><wicri:noRegion>Split 21000</wicri:noRegion></affiliation></author><author><name sortKey="Laatikainen, Tiina" sort="Laatikainen, Tiina" uniqKey="Laatikainen T" first="Tiina" last="Laatikainen">Tiina Laatikainen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name><affiliation wicri:level="1"><nlm:affiliation>Folkhälsan Research Centre, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Folkhälsan Research Centre, FI-00290 Helsinki</wicri:regionArea><wicri:noRegion>FI-00290 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Mateo Leach, Irene" sort="Mateo Leach, Irene" uniqKey="Mateo Leach I" first="Irene" last="Mateo Leach">Irene Mateo Leach</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Lee, Christine G" sort="Lee, Christine G" uniqKey="Lee C" first="Christine G" last="Lee">Christine G. Lee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Oregon Health and Science University, Portland, Oregon 97239</wicri:regionArea><wicri:noRegion>Oregon 97239</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Jong Young" sort="Lee, Jong Young" uniqKey="Lee J" first="Jong-Young" last="Lee">Jong-Young Lee</name><affiliation wicri:level="1"><nlm:affiliation>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914</wicri:regionArea><wicri:noRegion>Chungcheongbuk-do 370914</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Tian" sort="Liu, Tian" uniqKey="Liu T" first="Tian" last="Liu">Tian Liu</name><affiliation wicri:level="3"><nlm:affiliation>Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, 14195 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, 14195 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Youfang" sort="Liu, Youfang" uniqKey="Liu Y" first="Youfang" last="Liu">Youfang Liu</name><affiliation wicri:level="4"><nlm:affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280</wicri:regionArea><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName><placeName><settlement type="city">Chapel Hill (Caroline du Nord)</settlement><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Loh, Marie" sort="Loh, Marie" uniqKey="Loh M" first="Marie" last="Loh">Marie Loh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Lyytik Inen, Leo Pekka" sort="Lyytik Inen, Leo Pekka" uniqKey="Lyytik Inen L" first="Leo-Pekka" last="Lyytik Inen">Leo-Pekka Lyytik Inen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere</wicri:regionArea><wicri:noRegion>FI-33014 Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Medina Gomez, Carolina" sort="Medina Gomez, Carolina" uniqKey="Medina Gomez C" first="Carolina" last="Medina-Gomez">Carolina Medina-Gomez</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Michaelsson, Karl" sort="Michaelsson, Karl" uniqKey="Michaelsson K" first="Karl" last="Michaëlsson">Karl Michaëlsson</name><affiliation wicri:level="4"><nlm:affiliation>Department of Surgical Sciences, Orthopedics, Uppsala University, 751 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Surgical Sciences, Orthopedics, Uppsala University, 751 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Nalls, Mike A" sort="Nalls, Mike A" uniqKey="Nalls M" first="Mike A" last="Nalls">Mike A. Nalls</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Nielson, Carrie M" sort="Nielson, Carrie M" uniqKey="Nielson C" first="Carrie M" last="Nielson">Carrie M. Nielson</name><affiliation wicri:level="4"><nlm:affiliation>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239</wicri:regionArea><orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName><placeName><settlement type="city">Portland</settlement><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Oozageer, Laticia" sort="Oozageer, Laticia" uniqKey="Oozageer L" first="Laticia" last="Oozageer">Laticia Oozageer</name><affiliation wicri:level="1"><nlm:affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex UB1 3HW</wicri:regionArea><wicri:noRegion>Middlesex UB1 3HW</wicri:noRegion></affiliation></author><author><name sortKey="Pascoe, Laura" sort="Pascoe, Laura" uniqKey="Pascoe L" first="Laura" last="Pascoe">Laura Pascoe</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cell &Molecular Biosciences, Newcastle University, Newcastle NE1 7RU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cell &Molecular Biosciences, Newcastle University, Newcastle NE1 7RU</wicri:regionArea><wicri:noRegion>Newcastle NE1 7RU</wicri:noRegion></affiliation></author><author><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name><affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</nlm:affiliation><wicri:noCountry code="subField">UKnited</wicri:noCountry></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split, Split 21000</wicri:regionArea><wicri:noRegion>Split 21000</wicri:noRegion></affiliation></author><author><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Sarzynski, Mark A" sort="Sarzynski, Mark A" uniqKey="Sarzynski M" first="Mark A" last="Sarzynski">Mark A. Sarzynski</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808</wicri:regionArea><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Shin, Chan Soo" sort="Shin, Chan Soo" uniqKey="Shin C" first="Chan Soo" last="Shin">Chan Soo Shin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Naran I, Nina Smolej" sort="Naran I, Nina Smolej" uniqKey="Naran I N" first="Nina Smolej" last="Naran I">Nina Smolej Naran I</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Anthropological Research, Zagreb 10000, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Institute for Anthropological Research, Zagreb 10000</wicri:regionArea><wicri:noRegion>Zagreb 10000</wicri:noRegion></affiliation></author><author><name sortKey="Spira, Dominik" sort="Spira, Dominik" uniqKey="Spira D" first="Dominik" last="Spira">Dominik Spira</name><affiliation wicri:level="3"><nlm:affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Srikanth, Priya" sort="Srikanth, Priya" uniqKey="Srikanth P" first="Priya" last="Srikanth">Priya Srikanth</name><affiliation wicri:level="4"><nlm:affiliation>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239</wicri:regionArea><orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName><placeName><settlement type="city">Portland</settlement><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Steinhagen Thiessen, Elisabeth" sort="Steinhagen Thiessen, Elisabeth" uniqKey="Steinhagen Thiessen E" first="Elisabeth" last="Steinhagen-Thiessen">Elisabeth Steinhagen-Thiessen</name><affiliation wicri:level="3"><nlm:affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Sung, Yun Ju" sort="Sung, Yun Ju" uniqKey="Sung Y" first="Yun Ju" last="Sung">Yun Ju Sung</name><affiliation wicri:level="4"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Swart, Karin M A" sort="Swart, Karin M A" uniqKey="Swart K" first="Karin M A" last="Swart">Karin M A. Swart</name><affiliation wicri:level="1"><nlm:affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam</wicri:regionArea><wicri:noRegion>1081 BT Amsterdam</wicri:noRegion></affiliation></author><author><name sortKey="Taittonen, Leena" sort="Taittonen, Leena" uniqKey="Taittonen L" first="Leena" last="Taittonen">Leena Taittonen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Oulu, FI-90014 Oulu, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Pediatrics, University of Oulu, FI-90014 Oulu</wicri:regionArea><wicri:noRegion>FI-90014 Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="1"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225</wicri:regionArea><wicri:noRegion>Maryland 21225</wicri:noRegion></affiliation></author><author><name sortKey="Tikkanen, Emmi" sort="Tikkanen, Emmi" uniqKey="Tikkanen E" first="Emmi" last="Tikkanen">Emmi Tikkanen</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Van Der Velde, Nathalie" sort="Van Der Velde, Nathalie" uniqKey="Van Der Velde N" first="Nathalie" last="Van Der Velde">Nathalie Van Der Velde</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Schoor, Natasja M" sort="Van Schoor, Natasja M" uniqKey="Van Schoor N" first="Natasja M" last="Van Schoor">Natasja M. Van Schoor</name><affiliation wicri:level="1"><nlm:affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam</wicri:regionArea><wicri:noRegion>1081 BT Amsterdam</wicri:noRegion></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612</wicri:regionArea><wicri:noRegion>Illinois 60612</wicri:noRegion></affiliation></author><author><name sortKey="Zmuda, Joseph M" sort="Zmuda, Joseph M" uniqKey="Zmuda J" first="Joseph M" last="Zmuda">Joseph M. Zmuda</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology; University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology; University of Pittsburgh, Pittsburgh, Pennsylvania 15261</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Eklund, Niina" sort="Eklund, Niina" uniqKey="Eklund N" first="Niina" last="Eklund">Niina Eklund</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Forrester, Terrence" sort="Forrester, Terrence" uniqKey="Forrester T" first="Terrence" last="Forrester">Terrence Forrester</name><affiliation wicri:level="1"><nlm:affiliation>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica.</nlm:affiliation><country xml:lang="fr">Jamaïque</country><wicri:regionArea>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15</wicri:regionArea><wicri:noRegion>Mona JMAAW15</wicri:noRegion></affiliation></author><author><name sortKey="Grarup, Niels" sort="Grarup, Niels" uniqKey="Grarup N" first="Niels" last="Grarup">Niels Grarup</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Kristiansson, Kati" sort="Kristiansson, Kati" uniqKey="Kristiansson K" first="Kati" last="Kristiansson">Kati Kristiansson</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Kuulasmaa, Teemu" sort="Kuulasmaa, Teemu" uniqKey="Kuulasmaa T" first="Teemu" last="Kuulasmaa">Teemu Kuulasmaa</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio</wicri:regionArea><wicri:noRegion>70210 Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio</wicri:regionArea><wicri:noRegion>70210 Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Lichtner, Peter" sort="Lichtner, Peter" uniqKey="Lichtner P" first="Peter" last="Lichtner">Peter Lichtner</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Palmer, Cameron D" sort="Palmer, Cameron D" uniqKey="Palmer C" first="Cameron D" last="Palmer">Cameron D. Palmer</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142</wicri:regionArea><wicri:noRegion>Cambridge 2142</wicri:noRegion></affiliation></author><author><name sortKey="Ried, Janina S" sort="Ried, Janina S" uniqKey="Ried J" first="Janina S" last="Ried">Janina S. Ried</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A" last="Scott">Robert A. Scott</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Stancakova, Alena" sort="Stancakova, Alena" uniqKey="Stancakova A" first="Alena" last="Stancáková">Alena Stancáková</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio</wicri:regionArea><wicri:noRegion>70210 Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Wagner, Peter J" sort="Wagner, Peter J" uniqKey="Wagner P" first="Peter J" last="Wagner">Peter J. Wagner</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Demirkan, Ayse" sort="Demirkan, Ayse" uniqKey="Demirkan A" first="Ayse" last="Demirkan">Ayse Demirkan</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Doring, Angela" sort="Doring, Angela" uniqKey="Doring A" first="Angela" last="Döring">Angela Döring</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:affiliation>Icelandic Heart Association, Kopavogur 201, Iceland.</nlm:affiliation><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur 201</wicri:regionArea><wicri:noRegion>Kopavogur 201</wicri:noRegion></affiliation></author><author><name sortKey="Kiel, Douglas P" sort="Kiel, Douglas P" uniqKey="Kiel D" first="Douglas P" last="Kiel">Douglas P. Kiel</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Kuhnel, Brigitte" sort="Kuhnel, Brigitte" uniqKey="Kuhnel B" first="Brigitte" last="Kühnel">Brigitte Kühnel</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation wicri:level="4"><nlm:affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101</wicri:regionArea><orgName type="university">Université de Washington</orgName><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R" last="O'Connell">Jeffrey R. O'Connell</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201</wicri:regionArea><wicri:noRegion>Maryland 21201</wicri:noRegion></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation wicri:level="1"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><affiliation wicri:level="1"><nlm:affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201</wicri:regionArea><wicri:noRegion>Maryland 21201</wicri:noRegion></affiliation></author><author><name sortKey="Song, Kijoung" sort="Song, Kijoung" uniqKey="Song K" first="Kijoung" last="Song">Kijoung Song</name><affiliation wicri:level="1"><nlm:affiliation>Genetics, Projects Clinical Platforms and Sciences, GlaxoSmithKline, Philadelphia, Pennsylvania 19112, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Genetics, Projects Clinical Platforms and Sciences, GlaxoSmithKline, Philadelphia, Pennsylvania 19112</wicri:regionArea><wicri:noRegion>Pennsylvania 19112</wicri:noRegion></affiliation></author><author><name sortKey="Vandenput, Liesbeth" sort="Vandenput, Liesbeth" uniqKey="Vandenput L" first="Liesbeth" last="Vandenput">Liesbeth Vandenput</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg</wicri:regionArea><wicri:noRegion>413 45 Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</nlm:affiliation><wicri:noCountry code="subField">Rotterdam The Netherlands</wicri:noCountry></affiliation></author><author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="White, Charles C" sort="White, Charles C" uniqKey="White C" first="Charles C" last="White">Charles C. White</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation wicri:level="1"><nlm:affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Boettcher, Yvonne" sort="Boettcher, Yvonne" uniqKey="Boettcher Y" first="Yvonne" last="Boettcher">Yvonne Boettcher</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Cooper, Richard S" sort="Cooper, Richard S" uniqKey="Cooper R" first="Richard S" last="Cooper">Richard S. Cooper</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053</wicri:regionArea><wicri:noRegion>Illinois 61053</wicri:noRegion></affiliation></author><author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G" last="Forouhi">Nita G. Forouhi</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Hingorani, Aroon" sort="Hingorani, Aroon" uniqKey="Hingorani A" first="Aroon" last="Hingorani">Aroon Hingorani</name><affiliation wicri:level="4"><nlm:affiliation>Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cardiovascular Science, University College London, London WC1E 6BT</wicri:regionArea><orgName type="university">University College de Londres</orgName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="J Rgensen, Torben" sort="J Rgensen, Torben" uniqKey="J Rgensen T" first="Torben" last="J Rgensen">Torben J Rgensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Jousilahti, Pekka" sort="Jousilahti, Pekka" uniqKey="Jousilahti P" first="Pekka" last="Jousilahti">Pekka Jousilahti</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, UCL, London WC1E 6BT</wicri:regionArea><wicri:noRegion>London WC1E 6BT</wicri:noRegion></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, UCL, London WC1E 6BT</wicri:regionArea><wicri:noRegion>London WC1E 6BT</wicri:noRegion></affiliation></author><author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio</wicri:regionArea><wicri:noRegion>70210 Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Linneberg, Allan" sort="Linneberg, Allan" uniqKey="Linneberg A" first="Allan" last="Linneberg">Allan Linneberg</name><affiliation wicri:level="1"><nlm:affiliation>Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup</wicri:regionArea><wicri:noRegion>2600 Glostrup</wicri:noRegion></affiliation></author><author><name sortKey="Luke, Amy" sort="Luke, Amy" uniqKey="Luke A" first="Amy" last="Luke">Amy Luke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053</wicri:regionArea><wicri:noRegion>Illinois 61053</wicri:noRegion></affiliation></author><author><name sortKey="Mckenzie, Colin A" sort="Mckenzie, Colin A" uniqKey="Mckenzie C" first="Colin A" last="Mckenzie">Colin A. Mckenzie</name><affiliation wicri:level="1"><nlm:affiliation>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica.</nlm:affiliation><country xml:lang="fr">Jamaïque</country><wicri:regionArea>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15</wicri:regionArea><wicri:noRegion>Mona JMAAW15</wicri:noRegion></affiliation></author><author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Pedersen, Oluf" sort="Pedersen, Oluf" uniqKey="Pedersen O" first="Oluf" last="Pedersen">Oluf Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Tayo, Bamidele O" sort="Tayo, Bamidele O" uniqKey="Tayo B" first="Bamidele O" last="Tayo">Bamidele O. Tayo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053</wicri:regionArea><wicri:noRegion>Illinois 61053</wicri:noRegion></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><affiliation wicri:level="1"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612</wicri:regionArea><wicri:noRegion>Illinois 60612</wicri:noRegion></affiliation></author><author><name sortKey="Bertram, Lars" sort="Bertram, Lars" uniqKey="Bertram L" first="Lars" last="Bertram">Lars Bertram</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health, Faculty of Medicine, Imperial College London, London W6 8RP, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Public Health, Faculty of Medicine, Imperial College London, London W6 8RP</wicri:regionArea><wicri:noRegion>London W6 8RP</wicri:noRegion></affiliation></author><author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><affiliation wicri:level="2"><nlm:affiliation>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville</wicri:cityArea></affiliation></author><author><name sortKey="Bluher, Matthias" sort="Bluher, Matthias" uniqKey="Bluher M" first="Matthias" last="Blüher">Matthias Blüher</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808</wicri:regionArea><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Cho, Nam H" sort="Cho, Nam H" uniqKey="Cho N" first="Nam H" last="Cho">Nam H. Cho</name><affiliation wicri:level="1"><nlm:affiliation>Ajou University School of Medicine, Department of Preventive Medicine, Suwon Kyoung-gi 443-721, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Ajou University School of Medicine, Department of Preventive Medicine, Suwon Kyoung-gi 443-721</wicri:regionArea><wicri:noRegion>Suwon Kyoung-gi 443-721</wicri:noRegion></affiliation></author><author><name sortKey="Cummings, Steven R" sort="Cummings, Steven R" uniqKey="Cummings S" first="Steven R" last="Cummings">Steven R. Cummings</name><affiliation wicri:level="1"><nlm:affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Pacific Medical Center Research Institute, San Francisco, California 94107</wicri:regionArea><wicri:noRegion>California 94107</wicri:noRegion></affiliation></author><author><name sortKey="Czerwinski, Stefan A" sort="Czerwinski, Stefan A" uniqKey="Czerwinski S" first="Stefan A" last="Czerwinski">Stefan A. Czerwinski</name><affiliation wicri:level="1"><nlm:affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420</wicri:regionArea><wicri:noRegion>Ohio 45420</wicri:noRegion></affiliation></author><author><name sortKey="Demuth, Ilja" sort="Demuth, Ilja" uniqKey="Demuth I" first="Ilja" last="Demuth">Ilja Demuth</name><affiliation wicri:level="3"><nlm:affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Eckardt, Rahel" sort="Eckardt, Rahel" uniqKey="Eckardt R" first="Rahel" last="Eckardt">Rahel Eckardt</name><affiliation wicri:level="3"><nlm:affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="1"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225</wicri:regionArea><wicri:noRegion>Maryland 21225</wicri:noRegion></affiliation></author><author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H" last="Franco">Oscar H. Franco</name><affiliation><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</nlm:affiliation><wicri:noCountry code="subField">Rotterdam The Netherlands</wicri:noCountry></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T" last="Gansevoort">Ron T. Gansevoort</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Hastie, Nicholas" sort="Hastie, Nicholas" uniqKey="Hastie N" first="Nicholas" last="Hastie">Nicholas Hastie</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Heliovaara, Markku" sort="Heliovaara, Markku" uniqKey="Heliovaara M" first="Markku" last="Heliövaara">Markku Heliövaara</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation><nlm:affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</nlm:affiliation><wicri:noCountry code="subField">Rotterdam The Netherlands</wicri:noCountry></affiliation></author><author><name sortKey="Jordan, Joanne M" sort="Jordan, Joanne M" uniqKey="Jordan J" first="Joanne M" last="Jordan">Joanne M. Jordan</name><affiliation wicri:level="4"><nlm:affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280</wicri:regionArea><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName><placeName><settlement type="city">Chapel Hill (Caroline du Nord)</settlement><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Physiology, Tampere University Hospital, FI-33521 Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology, Tampere University Hospital, FI-33521 Tampere</wicri:regionArea><wicri:noRegion>FI-33521 Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Kajantie, Eero" sort="Kajantie, Eero" uniqKey="Kajantie E" first="Eero" last="Kajantie">Eero Kajantie</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Knekt, Paul B" sort="Knekt, Paul B" uniqKey="Knekt P" first="Paul B" last="Knekt">Paul B. Knekt</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Koskinen, Seppo" sort="Koskinen, Seppo" uniqKey="Koskinen S" first="Seppo" last="Koskinen">Seppo Koskinen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere</wicri:regionArea><wicri:noRegion>FI-33014 Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Sciences, Uppsala University, 751 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation wicri:level="1"><nlm:affiliation>Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157</wicri:regionArea><wicri:noRegion>North Carolina 27157</wicri:noRegion></affiliation></author><author><name sortKey="Orwoll, Eric S" sort="Orwoll, Eric S" uniqKey="Orwoll E" first="Eric S" last="Orwoll">Eric S. Orwoll</name><affiliation wicri:level="4"><nlm:affiliation>Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239</wicri:regionArea><orgName type="university">Université des sciences et de la médecine de l'Oregon</orgName><placeName><settlement type="city">Portland</settlement><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Osmond, Clive" sort="Osmond, Clive" uniqKey="Osmond C" first="Clive" last="Osmond">Clive Osmond</name><affiliation wicri:level="1"><nlm:affiliation>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD</wicri:regionArea><wicri:noRegion>Southampton SO16 6YD</wicri:noRegion></affiliation></author><author><name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Perusse, Louis" sort="Perusse, Louis" uniqKey="Perusse L" first="Louis" last="Pérusse">Louis Pérusse</name><affiliation wicri:level="1"><nlm:affiliation>Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department of Kinesiology, Laval University, Québec City, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T" last="Raitakari">Olli T. Raitakari</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku</wicri:regionArea><wicri:noRegion>FI-20521 Turku</wicri:noRegion></affiliation></author><author><name sortKey="Rankinen, Tuomo" sort="Rankinen, Tuomo" uniqKey="Rankinen T" first="Tuomo" last="Rankinen">Tuomo Rankinen</name><affiliation wicri:level="1"><nlm:affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808</wicri:regionArea><placeName><settlement type="city">Los Angeles</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Rao, D C" sort="Rao, D C" uniqKey="Rao D" first="D C" last="Rao">D C Rao</name><affiliation wicri:level="4"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Rice, Treva K" sort="Rice, Treva K" uniqKey="Rice T" first="Treva K" last="Rice">Treva K. Rice</name><affiliation wicri:level="4"><nlm:affiliation>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="S Rensen, Thorkild I A" sort="S Rensen, Thorkild I A" uniqKey="S Rensen T" first="Thorkild I A" last="S Rensen">Thorkild I A. S Rensen</name><affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</nlm:affiliation><wicri:noCountry code="subField">UKnited</wicri:noCountry></affiliation></author><author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name><affiliation wicri:level="3"><nlm:affiliation>University of Leipzig, Department of Medicine, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, Department of Medicine, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Towne, Bradford" sort="Towne, Bradford" uniqKey="Towne B" first="Bradford" last="Towne">Bradford Towne</name><affiliation wicri:level="1"><nlm:affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420</wicri:regionArea><wicri:noRegion>Ohio 45420</wicri:noRegion></affiliation></author><author><name sortKey="Tranah, Gregory J" sort="Tranah, Gregory J" uniqKey="Tranah G" first="Gregory J" last="Tranah">Gregory J. Tranah</name><affiliation wicri:level="1"><nlm:affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Pacific Medical Center Research Institute, San Francisco, California 94107</wicri:regionArea><wicri:noRegion>California 94107</wicri:noRegion></affiliation></author><author><name sortKey="Tremblay, Angelo" sort="Tremblay, Angelo" uniqKey="Tremblay A" first="Angelo" last="Tremblay">Angelo Tremblay</name><affiliation wicri:level="1"><nlm:affiliation>Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department of Kinesiology, Laval University, Québec City, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Vartiainen, Erkki" sort="Vartiainen, Erkki" uniqKey="Vartiainen E" first="Erkki" last="Vartiainen">Erkki Vartiainen</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, FI-00271 Helsinki</wicri:regionArea><wicri:noRegion>FI-00271 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Viikari, Jorma S" sort="Viikari, Jorma S" uniqKey="Viikari J" first="Jorma S" last="Viikari">Jorma S. Viikari</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, University of Turku, FI-20521 Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Turku, FI-20521 Turku</wicri:regionArea><orgName type="university">Université de Turku</orgName><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Vohl, Marie Claude" sort="Vohl, Marie Claude" uniqKey="Vohl M" first="Marie-Claude" last="Vohl">Marie-Claude Vohl</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada G1V 0A6.</nlm:affiliation><country>Canada</country><wicri:regionArea>Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Walker, Mark" sort="Walker, Mark" uniqKey="Walker M" first="Mark" last="Walker">Mark Walker</name><affiliation wicri:level="1"><nlm:affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation></author><author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Wild, Sarah" sort="Wild, Sarah" uniqKey="Wild S" first="Sarah" last="Wild">Sarah Wild</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loïc" last="Yengo">Loïc Yengo</name><affiliation wicri:level="1"><nlm:affiliation>CNRS UMR 8199, F-59019 Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CNRS UMR 8199, F-59019 Lille</wicri:regionArea><wicri:noRegion>59019 Lille</wicri:noRegion><wicri:noRegion>59019 Lille</wicri:noRegion></affiliation></author><author><name sortKey="Bishop, D Timothy" sort="Bishop, D Timothy" uniqKey="Bishop D" first="D Timothy" last="Bishop">D Timothy Bishop</name><affiliation wicri:level="4"><nlm:affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B" last="Borecki">Ingrid B. Borecki</name><affiliation wicri:level="4"><nlm:affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108</wicri:regionArea><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName><placeName><settlement type="city">Saint-Louis (Missouri)</settlement><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Cupples, L Adrienne" sort="Cupples, L Adrienne" uniqKey="Cupples L" first="L Adrienne" last="Cupples">L Adrienne Cupples</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation></author><author><name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Erasmus Medical Center, 3000CA Rotterdam/Zuidholland, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus Medical Center, 3000CA Rotterdam/Zuidholland</wicri:regionArea><wicri:noRegion>3000CA Rotterdam/Zuidholland</wicri:noRegion></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation wicri:level="4"><nlm:affiliation>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ</wicri:regionArea><orgName type="university">Université de Londres</orgName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fatemifar, Ghazaleh" sort="Fatemifar, Ghazaleh" uniqKey="Fatemifar G" first="Ghazaleh" last="Fatemifar">Ghazaleh Fatemifar</name><affiliation><nlm:affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</nlm:affiliation><wicri:noCountry code="subField">UKnited</wicri:noCountry></affiliation></author><author><name sortKey="Fox, Caroline" sort="Fox, Caroline" uniqKey="Fox C" first="Caroline" last="Fox">Caroline Fox</name><affiliation wicri:level="1"><nlm:affiliation>Harvard Medical School, Boston, Massachusetts 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts 02115</wicri:regionArea><wicri:noRegion>Massachusetts 02115</wicri:noRegion></affiliation></author><author><name sortKey="Furey, Terrence S" sort="Furey, Terrence S" uniqKey="Furey T" first="Terrence S" last="Furey">Terrence S. Furey</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599</wicri:regionArea><wicri:noRegion>North Carolina 27599</wicri:noRegion></affiliation></author><author><name sortKey="Franke, Lude" sort="Franke, Lude" uniqKey="Franke L" first="Lude" last="Franke">Lude Franke</name><affiliation wicri:level="4"><nlm:affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen</wicri:regionArea><orgName type="university">Université de Groningue</orgName><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Han, Jiali" sort="Han, Jiali" uniqKey="Han J" first="Jiali" last="Han">Jiali Han</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202</wicri:regionArea><wicri:noRegion>Indiana 46202</wicri:noRegion></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142</wicri:regionArea><wicri:noRegion>Cambridge 2142</wicri:noRegion></affiliation></author><author><name sortKey="Karjalainen, Juha" sort="Karjalainen, Juha" uniqKey="Karjalainen J" first="Juha" last="Karjalainen">Juha Karjalainen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen</wicri:regionArea><wicri:noRegion>9700 RB Groningen</wicri:noRegion></affiliation></author><author><name sortKey="Karpe, Fredrik" sort="Karpe, Fredrik" uniqKey="Karpe F" first="Fredrik" last="Karpe">Fredrik Karpe</name><affiliation wicri:level="4"><nlm:affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Kaplan, Robert C" sort="Kaplan, Robert C" uniqKey="Kaplan R" first="Robert C" last="Kaplan">Robert C. Kaplan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461</wicri:regionArea><wicri:noRegion>New York 10461</wicri:noRegion></affiliation></author><author><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><affiliation wicri:level="1"><nlm:affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex UB1 3HW</wicri:regionArea><wicri:noRegion>Middlesex UB1 3HW</wicri:noRegion></affiliation></author><author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Murabito, Joanne M" sort="Murabito, Joanne M" uniqKey="Murabito J" first="Joanne M" last="Murabito">Joanne M. Murabito</name><affiliation wicri:level="1"><nlm:affiliation>Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, Massachusetts 02118, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation></author><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P" last="Morris">Andrew P. Morris</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Bishop, Julia A N" sort="Bishop, Julia A N" uniqKey="Bishop J" first="Julia A N" last="Bishop">Julia A N. Bishop</name><affiliation wicri:level="4"><nlm:affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name><affiliation wicri:level="4"><nlm:affiliation>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7400</wicri:regionArea><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName><placeName><settlement type="city">Chapel Hill (Caroline du Nord)</settlement><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Ohlsson, Claes" sort="Ohlsson, Claes" uniqKey="Ohlsson C" first="Claes" last="Ohlsson">Claes Ohlsson</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg</wicri:regionArea><wicri:noRegion>413 45 Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K" last="Ong">Ken K. Ong</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Richards, J Brent" sort="Richards, J Brent" uniqKey="Richards J" first="J Brent" last="Richards">J Brent Richards</name><affiliation wicri:level="4"><nlm:affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Schadt, Eric E" sort="Schadt, Eric E" uniqKey="Schadt E" first="Eric E" last="Schadt">Eric E. Schadt</name><affiliation wicri:level="1"><nlm:affiliation>Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029</wicri:regionArea><wicri:noRegion>New York 10029</wicri:noRegion></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="1"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Widen, Elisabeth" sort="Widen, Elisabeth" uniqKey="Widen E" first="Elisabeth" last="Widén">Elisabeth Widén</name><affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Willer, Cristen J" sort="Willer, Cristen J" uniqKey="Willer C" first="Cristen J" last="Willer">Cristen J. Willer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109</wicri:regionArea><wicri:noRegion>Michigan 48109</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Jian" sort="Yang, Jian" uniqKey="Yang J" first="Jian" last="Yang">Jian Yang</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, The University of Queensland, Brisbane 4072</wicri:regionArea><wicri:noRegion>Brisbane 4072</wicri:noRegion></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation wicri:level="4"><nlm:affiliation>Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Science for Life Laboratory, Uppsala University, 750 85 Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L" last="Mohlke">Karen L. Mohlke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599</wicri:regionArea><wicri:noRegion>North Carolina 27599</wicri:noRegion></affiliation></author><author><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N" last="Hirschhorn">Joel N. Hirschhorn</name><affiliation wicri:level="1"><nlm:affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142</wicri:regionArea><wicri:noRegion>Cambridge 2142</wicri:noRegion></affiliation></author><author><name sortKey="Pospisilik, John Andrew" sort="Pospisilik, John Andrew" uniqKey="Pospisilik J" first="John Andrew" last="Pospisilik">John Andrew Pospisilik</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epigenetics, Max Planck Institute of Immunobiology and Epigenetics, D-76108 Freiburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Epigenetics, Max Planck Institute of Immunobiology and Epigenetics, D-76108 Freiburg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Zillikens, M Carola" sort="Zillikens, M Carola" uniqKey="Zillikens M" first="M Carola" last="Zillikens">M Carola Zillikens</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Lindgren, Cecilia" sort="Lindgren, Cecilia" uniqKey="Lindgren C" first="Cecilia" last="Lindgren">Cecilia Lindgren</name><affiliation wicri:level="4"><nlm:affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Kilpel Inen, Tuomas Oskari" sort="Kilpel Inen, Tuomas Oskari" uniqKey="Kilpel Inen T" first="Tuomas Oskari" last="Kilpel Inen">Tuomas Oskari Kilpel Inen</name><affiliation wicri:level="1"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ</wicri:regionArea><wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><affiliation wicri:level="1"><nlm:affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029</wicri:regionArea><wicri:noRegion>New York 10029</wicri:noRegion></affiliation></author></analytic><series><title level="j">Nature communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adiposity (genetics)</term><term>Animals</term><term>Drosophila melanogaster (genetics)</term><term>Drosophila melanogaster (metabolism)</term><term>Gene Expression Regulation (physiology)</term><term>Gene Knockdown Techniques</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Heart Diseases (genetics)</term><term>Humans</term><term>Quantitative Trait Loci (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adiposité (génétique)</term><term>Animaux</term><term>Cardiopathies (génétique)</term><term>Drosophila melanogaster (génétique)</term><term>Drosophila melanogaster (métabolisme)</term><term>Humains</term><term>Locus de caractère quantitatif (génétique)</term><term>Prédisposition génétique à une maladie</term><term>Régulation de l'expression des gènes (physiologie)</term><term>Techniques de knock-down de gènes</term><term>Étude d'association pangénomique</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Adiposity</term><term>Drosophila melanogaster</term><term>Heart Diseases</term><term>Quantitative Trait Loci</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Adiposité</term><term>Cardiopathies</term><term>Drosophila melanogaster</term><term>Locus de caractère quantitatif</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Drosophila melanogaster</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Drosophila melanogaster</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Régulation de l'expression des gènes</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Gene Expression Regulation</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Gene Knockdown Techniques</term><term>Genetic Predisposition to Disease</term><term>Genome-Wide Association Study</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Prédisposition génétique à une maladie</term><term>Techniques de knock-down de gènes</term><term>Étude d'association pangénomique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals. Twelve loci reached genome-wide significance (P<5 × 10(-8)), of which eight were previously associated with increased overall adiposity (BMI, BF%) and four (in or near COBLL1/GRB14, IGF2BP1, PLA2G6, CRTC1) were novel associations with BF%. Seven loci showed a larger effect on BF% than on BMI, suggestive of a primary association with adiposity, while five loci showed larger effects on BMI than on BF%, suggesting association with both fat and lean mass. In particular, the loci more strongly associated with BF% showed distinct cross-phenotype association signatures with a range of cardiometabolic traits revealing new insights in the link between adiposity and disease risk.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26833246</PMID><DateCreated><Year>2016</Year><Month>02</Month><Day>02</Day></DateCreated><DateCompleted><Year>2016</Year><Month>06</Month><Day>17</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2041-1723</ISSN><JournalIssue CitedMedium="Internet"><Volume>7</Volume><PubDate><Year>2016</Year><Month>Feb</Month><Day>01</Day></PubDate></JournalIssue><Title>Nature communications</Title><ISOAbbreviation>Nat Commun</ISOAbbreviation></Journal><ArticleTitle>New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.</ArticleTitle><Pagination><MedlinePgn>10495</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/ncomms10495</ELocationID><Abstract><AbstractText>To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals. Twelve loci reached genome-wide significance (P<5 × 10(-8)), of which eight were previously associated with increased overall adiposity (BMI, BF%) and four (in or near COBLL1/GRB14, IGF2BP1, PLA2G6, CRTC1) were novel associations with BF%. Seven loci showed a larger effect on BF% than on BMI, suggestive of a primary association with adiposity, while five loci showed larger effects on BMI than on BF%, suggesting association with both fat and lean mass. In particular, the loci more strongly associated with BF% showed distinct cross-phenotype association signatures with a range of cardiometabolic traits revealing new insights in the link between adiposity and disease risk.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Yingchang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Day</LastName><ForeName>Felix R</ForeName><Initials>FR</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-3789-7651</Identifier><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gustafsson</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-5894-0351</Identifier><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medical Sciences, Molecular Epidemiology, Uppsala University, 751 85 Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buchkovich</LastName><ForeName>Martin L</ForeName><Initials>ML</Initials><AffiliationInfo><Affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Na</LastName><ForeName>Jianbo</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Developmental and Regenerative Biology, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bataille</LastName><ForeName>Veronique</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>West Herts NHS Trust, Herts HP2 4AD, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cousminer</LastName><ForeName>Diana L</ForeName><Initials>DL</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dastani</LastName><ForeName>Zari</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Drong</LastName><ForeName>Alexander W</ForeName><Initials>AW</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Esko</LastName><ForeName>Tõnu</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>David M</ForeName><Initials>DM</Initials><AffiliationInfo><Affiliation>University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland 4102, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Falchi</LastName><ForeName>Mario</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Feitosa</LastName><ForeName>Mary F</ForeName><Initials>MF</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferreira</LastName><ForeName>Teresa</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hedman</LastName><ForeName>Åsa K</ForeName><Initials>ÅK</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medical Sciences, Molecular Epidemiology, Uppsala University, 751 85 Uppsala, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haring</LastName><ForeName>Robin</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>European University of Applied Sciences, Faculty of Applied Public Health, 18055 Rostock, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hysi</LastName><ForeName>Pirro G</ForeName><Initials>PG</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Iles</LastName><ForeName>Mark M</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Justice</LastName><ForeName>Anne E</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kanoni</LastName><ForeName>Stavroula</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lagou</LastName><ForeName>Vasiliki</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Rui</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Xin</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Locke</LastName><ForeName>Adam</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Chen</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mägi</LastName><ForeName>Reedik</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perry</LastName><ForeName>John R B</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pers</LastName><ForeName>Tune H</ForeName><Initials>TH</Initials><AffiliationInfo><Affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge 02142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology Research, Statens Serum Institut, 2100 Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qi</LastName><ForeName>Qibin</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanna</LastName><ForeName>Marianna</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Ellen M</ForeName><Initials>EM</Initials><AffiliationInfo><Affiliation>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scott</LastName><ForeName>William R</ForeName><Initials>WR</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shungin</LastName><ForeName>Dmitry</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Lund University Diabetes Centre, Department of Clinical Science, Genetic and Molecular Epidemiology Unit, Skåne University Hosptial, 205 02 Malmö, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, 901 87 Umeå, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Odontology, Umeå University, 901 85 Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Teumer</LastName><ForeName>Alexander</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vinkhuyzen</LastName><ForeName>Anna A E</ForeName><Initials>AA</Initials><AffiliationInfo><Affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walker</LastName><ForeName>Ryan W</ForeName><Initials>RW</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Westra</LastName><ForeName>Harm-Jan</ForeName><Initials>HJ</Initials><AffiliationInfo><Affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02446, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Partners Center for Personalized Genetic Medicine, Boston, Massachusetts 02446, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Mingfeng</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Weihua</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Jing Hua</ForeName><Initials>JH</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhu</LastName><ForeName>Zhihong</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Afzal</LastName><ForeName>Uzma</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ahluwalia</LastName><ForeName>Tarunveer Singh</ForeName><Initials>TS</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health and Medical Sceinces, University of Copenhagen, 2200 Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Danish Pediatric Asthma Center, Gentofte Hospital, The Capital Region, 2200 Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Steno Diabetes Center A/S, DK-2820 Gentofte, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bakker</LastName><ForeName>Stephan J L</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bellis</LastName><ForeName>Claire</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bonnefond</LastName><ForeName>Amélie</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, F-59019 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>European Genomic Institute for Diabetes, 59000 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université de Lille 2, 59000 Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borodulin</LastName><ForeName>Katja</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buchman</LastName><ForeName>Aron S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cederholm</LastName><ForeName>Tommy</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 751 85 Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Choh</LastName><ForeName>Audrey C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Choi</LastName><ForeName>Hyung Jin</ForeName><Initials>HJ</Initials><AffiliationInfo><Affiliation>Department of Anatomy, Seoul National University College of Medicine, Seoul 03080, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Curran</LastName><ForeName>Joanne E</ForeName><Initials>JE</Initials><AffiliationInfo><Affiliation>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Groot</LastName><ForeName>Lisette C P G M</ForeName><Initials>LC</Initials><AffiliationInfo><Affiliation>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Jager</LastName><ForeName>Philip L</ForeName><Initials>PL</Initials><AffiliationInfo><Affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Harvard Medical School, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dhonukshe-Rutten</LastName><ForeName>Rosalie A M</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Enneman</LastName><ForeName>Anke W</ForeName><Initials>AW</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eury</LastName><ForeName>Elodie</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, F-59019 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>European Genomic Institute for Diabetes, 59000 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université de Lille 2, 59000 Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>Daniel S</ForeName><Initials>DS</Initials><AffiliationInfo><Affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Forsen</LastName><ForeName>Tom</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Friedrich</LastName><ForeName>Nele</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fumeron</LastName><ForeName>Frédéric</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>INSERM, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Univ Paris Diderot, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Garcia</LastName><ForeName>Melissa E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gärtner</LastName><ForeName>Simone</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Han</LastName><ForeName>Bok-Ghee</ForeName><Initials>BG</Initials><AffiliationInfo><Affiliation>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Havulinna</LastName><ForeName>Aki S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hayward</LastName><ForeName>Caroline</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hernandez</LastName><ForeName>Dena</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hillege</LastName><ForeName>Hans</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ittermann</LastName><ForeName>Till</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kent</LastName><ForeName>Jack W</ForeName><Initials>JW</Initials><AffiliationInfo><Affiliation>Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kolcic</LastName><ForeName>Ivana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Laatikainen</LastName><ForeName>Tiina</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Hospital District of North Karelia, FI-80210 Joensuu, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Public Health and Clinical Nutrition, University of Eastern Finland, FI-70211 Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lahti</LastName><ForeName>Jari</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Folkhälsan Research Centre, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Behavioural Sciences, University of Helsinki, FI-00014 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mateo Leach</LastName><ForeName>Irene</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Christine G</ForeName><Initials>CG</Initials><AffiliationInfo><Affiliation>Department of Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Service, Veterans Affairs Medical Center, Portland, Oregon 97239, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Jong-Young</ForeName><Initials>JY</Initials><AffiliationInfo><Affiliation>Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Tian</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, 14195 Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Max Planck Institute for Human Development, 14194 Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Youfang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lobbens</LastName><ForeName>Stéphane</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, F-59019 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>European Genomic Institute for Diabetes, 59000 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université de Lille 2, 59000 Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Loh</LastName><ForeName>Marie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore 138648, Singapore.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lyytikäinen</LastName><ForeName>Leo-Pekka</ForeName><Initials>LP</Initials><AffiliationInfo><Affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, FI-33520 Tampere, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Medina-Gomez</LastName><ForeName>Carolina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Michaëlsson</LastName><ForeName>Karl</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Surgical Sciences, Orthopedics, Uppsala University, 751 85 Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nalls</LastName><ForeName>Mike A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nielson</LastName><ForeName>Carrie M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oozageer</LastName><ForeName>Laticia</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pascoe</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Institute of Cell &Molecular Biosciences, Newcastle University, Newcastle NE1 7RU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Paternoster</LastName><ForeName>Lavinia</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Polašek</LastName><ForeName>Ozren</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ripatti</LastName><ForeName>Samuli</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Hjelt Institute, University of Helsinki, FI-00014 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sarzynski</LastName><ForeName>Mark A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shin</LastName><ForeName>Chan Soo</ForeName><Initials>CS</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Narančić</LastName><ForeName>Nina Smolej</ForeName><Initials>NS</Initials><AffiliationInfo><Affiliation>Institute for Anthropological Research, Zagreb 10000, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spira</LastName><ForeName>Dominik</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Lipid Clinic at the Interdisciplinary Metabolism Center, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Srikanth</LastName><ForeName>Priya</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steinhagen-Thiessen</LastName><ForeName>Elisabeth</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Lipid Clinic at the Interdisciplinary Metabolism Center, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sung</LastName><ForeName>Yun Ju</ForeName><Initials>YJ</Initials><AffiliationInfo><Affiliation>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Swart</LastName><ForeName>Karin M A</ForeName><Initials>KM</Initials><AffiliationInfo><Affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>VUMC, Department of Epidemiology and Biostatistics, 1081 BT Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Taittonen</LastName><ForeName>Leena</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University of Oulu, FI-90014 Oulu, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Pediatrics, Vaasa Central Hospital, FI-65100 Vaasa, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tanaka</LastName><ForeName>Toshiko</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tikkanen</LastName><ForeName>Emmi</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Hjelt Institute, University of Helsinki, FI-00014 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Velde</LastName><ForeName>Nathalie</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Schoor</LastName><ForeName>Natasja M</ForeName><Initials>NM</Initials><AffiliationInfo><Affiliation>EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>VUMC, Department of Epidemiology and Biostatistics, 1081 BT Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Verweij</LastName><ForeName>Niek</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wright</LastName><ForeName>Alan F</ForeName><Initials>AF</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yu</LastName><ForeName>Lei</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zmuda</LastName><ForeName>Joseph M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Department of Epidemiology; University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eklund</LastName><ForeName>Niina</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Forrester</LastName><ForeName>Terrence</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grarup</LastName><ForeName>Niels</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jackson</LastName><ForeName>Anne U</ForeName><Initials>AU</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kristiansson</LastName><ForeName>Kati</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kuulasmaa</LastName><ForeName>Teemu</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kuusisto</LastName><ForeName>Johanna</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Kuopio University Hospital, 70029 Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lichtner</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luan</LastName><ForeName>Jian'an</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mahajan</LastName><ForeName>Anubha</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Männistö</LastName><ForeName>Satu</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Palmer</LastName><ForeName>Cameron D</ForeName><Initials>CD</Initials><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ried</LastName><ForeName>Janina S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scott</LastName><ForeName>Robert A</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stancáková</LastName><ForeName>Alena</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wagner</LastName><ForeName>Peter J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Demirkan</LastName><ForeName>Ayse</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Döring</LastName><ForeName>Angela</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gudnason</LastName><ForeName>Vilmundur</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Icelandic Heart Association, Kopavogur 201, Iceland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Iceland, Faculty of Medicine, Reykjavik 101, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kiel</LastName><ForeName>Douglas P</ForeName><Initials>DP</Initials><AffiliationInfo><Affiliation>Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute for Aging Research Hebrew Senior Life, Boston, Massachusetts 02131, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kühnel</LastName><ForeName>Brigitte</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mangino</LastName><ForeName>Massimo</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mcknight</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Menni</LastName><ForeName>Cristina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Connell</LastName><ForeName>Jeffrey R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oostra</LastName><ForeName>Ben A</ForeName><Initials>BA</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shuldiner</LastName><ForeName>Alan R</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland 21042, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Song</LastName><ForeName>Kijoung</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Genetics, Projects Clinical Platforms and Sciences, GlaxoSmithKline, Philadelphia, Pennsylvania 19112, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vandenput</LastName><ForeName>Liesbeth</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Duijn</LastName><ForeName>Cornelia M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Center for Medical Systems Biology, 2300 Leiden, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vollenweider</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>White</LastName><ForeName>Charles C</ForeName><Initials>CC</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boehnke</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boettcher</LastName><ForeName>Yvonne</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Leipzig, Department of Medicine, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cooper</LastName><ForeName>Richard S</ForeName><Initials>RS</Initials><AffiliationInfo><Affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Forouhi</LastName><ForeName>Nita G</ForeName><Initials>NG</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gieger</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grallert</LastName><ForeName>Harald</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hingorani</LastName><ForeName>Aroon</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jørgensen</LastName><ForeName>Torben</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Medicine, University of Aalborg, 9220 Aalborg, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Centre for Prevention and Health, DK2600 Capital Region of Denmark, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jousilahti</LastName><ForeName>Pekka</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kivimaki</LastName><ForeName>Mika</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kumari</LastName><ForeName>Meena</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Laakso</LastName><ForeName>Markku</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine, University of Eastern Finland, 70210 Kuopio, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Kuopio University Hospital, 70029 Kuopio, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Langenberg</LastName><ForeName>Claudia</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Linneberg</LastName><ForeName>Allan</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luke</LastName><ForeName>Amy</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mckenzie</LastName><ForeName>Colin A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Palotie</LastName><ForeName>Aarno</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts 02114, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pedersen</LastName><ForeName>Oluf</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peters</LastName><ForeName>Annette</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Strauch</LastName><ForeName>Konstantin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tayo</LastName><ForeName>Bamidele O</ForeName><Initials>BO</Initials><AffiliationInfo><Affiliation>Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wareham</LastName><ForeName>Nicholas J</ForeName><Initials>NJ</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bennett</LastName><ForeName>David A</ForeName><Initials>DA</Initials><AffiliationInfo><Affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bertram</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>School of Public Health, Faculty of Medicine, Imperial College London, London W6 8RP, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Integrative and Experimental Genomics, University of Lübeck, 23562 Lübeck, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blangero</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blüher</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Leipzig, Department of Medicine, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bouchard</LastName><ForeName>Claude</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Campbell</LastName><ForeName>Harry</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cho</LastName><ForeName>Nam H</ForeName><Initials>NH</Initials><AffiliationInfo><Affiliation>Ajou University School of Medicine, Department of Preventive Medicine, Suwon Kyoung-gi 443-721, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cummings</LastName><ForeName>Steven R</ForeName><Initials>SR</Initials><AffiliationInfo><Affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Czerwinski</LastName><ForeName>Stefan A</ForeName><Initials>SA</Initials><AffiliationInfo><Affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Demuth</LastName><ForeName>Ilja</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Medical and Human Genetics, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eckardt</LastName><ForeName>Rahel</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eriksson</LastName><ForeName>Johan G</ForeName><Initials>JG</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Folkhälsan Research Centre, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferrucci</LastName><ForeName>Luigi</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Franco</LastName><ForeName>Oscar H</ForeName><Initials>OH</Initials><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Froguel</LastName><ForeName>Philippe</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, F-59019 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>European Genomic Institute for Diabetes, 59000 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université de Lille 2, 59000 Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gansevoort</LastName><ForeName>Ron T</ForeName><Initials>RT</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hansen</LastName><ForeName>Torben</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Health Sciences, University of Southern Denmark, 5000 Odense, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harris</LastName><ForeName>Tamara B</ForeName><Initials>TB</Initials><AffiliationInfo><Affiliation>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hastie</LastName><ForeName>Nicholas</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heliövaara</LastName><ForeName>Markku</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hofman</LastName><ForeName>Albert</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jordan</LastName><ForeName>Joanne M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jula</LastName><ForeName>Antti</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kähönen</LastName><ForeName>Mika</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Clinical Physiology, Tampere University Hospital, FI-33521 Tampere, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Clinical Physiology, University of Tampere School of Medicine, FI-33014 Tampere, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kajantie</LastName><ForeName>Eero</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Children's Hospital, Helsinki University Hospital and University of Helsinki, FI-00029 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, MRC Oulu, Oulu University Hospital and University of Oulu, FI-90029 Oulu, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Knekt</LastName><ForeName>Paul B</ForeName><Initials>PB</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koskinen</LastName><ForeName>Seppo</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kovacs</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lehtimäki</LastName><ForeName>Terho</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, FI-33520 Tampere, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lind</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Yongmei</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Orwoll</LastName><ForeName>Eric S</ForeName><Initials>ES</Initials><AffiliationInfo><Affiliation>Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Osmond</LastName><ForeName>Clive</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perola</LastName><ForeName>Markus</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pérusse</LastName><ForeName>Louis</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada G1V 0A6.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raitakari</LastName><ForeName>Olli T</ForeName><Initials>OT</Initials><AffiliationInfo><Affiliation>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20520 Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rankinen</LastName><ForeName>Tuomo</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rao</LastName><ForeName>D C</ForeName><Initials>DC</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rice</LastName><ForeName>Treva K</ForeName><Initials>TK</Initials><AffiliationInfo><Affiliation>Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rivadeneira</LastName><ForeName>Fernando</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudan</LastName><ForeName>Igor</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Salomaa</LastName><ForeName>Veikko</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sørensen</LastName><ForeName>Thorkild I A</ForeName><Initials>TI</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, 2000 Frederiksberg, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stumvoll</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Leipzig, Department of Medicine, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tönjes</LastName><ForeName>Anke</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>University of Leipzig, Department of Medicine, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Towne</LastName><ForeName>Bradford</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tranah</LastName><ForeName>Gregory J</ForeName><Initials>GJ</Initials><AffiliationInfo><Affiliation>California Pacific Medical Center Research Institute, San Francisco, California 94107, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tremblay</LastName><ForeName>Angelo</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Uitterlinden</LastName><ForeName>André G</ForeName><Initials>AG</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Harst</LastName><ForeName>Pim</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, 3501 DG Utrecht, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vartiainen</LastName><ForeName>Erkki</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>National Institute for Health and Welfare, FI-00271 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Viikari</LastName><ForeName>Jorma S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Turku, FI-20521 Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vitart</LastName><ForeName>Veronique</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vohl</LastName><ForeName>Marie-Claude</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada G1V 0A6.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>School of Nutrition, Laval University, Québec City, Quebec, Canada G1V 0A6.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Völzke</LastName><ForeName>Henry</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>DZHK (German Centre for Cardiovascular Research), partner site Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>DZD (German Centre for Diabetes Research), partner site Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walker</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Cellular Medicine, Newcastle University, Newcastle NE2 4HH, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wallaschofski</LastName><ForeName>Henri</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>DZHK (German Centre for Cardiovascular Research), partner site Greifswald, 17475 Greifswald, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wild</LastName><ForeName>Sarah</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wilson</LastName><ForeName>James F</ForeName><Initials>JF</Initials><AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yengo</LastName><ForeName>Loïc</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>CNRS UMR 8199, F-59019 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>European Genomic Institute for Diabetes, 59000 Lille, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université de Lille 2, 59000 Lille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bishop</LastName><ForeName>D Timothy</ForeName><Initials>DT</Initials><AffiliationInfo><Affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borecki</LastName><ForeName>Ingrid B</ForeName><Initials>IB</Initials><AffiliationInfo><Affiliation>Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Analytical Genetics Group, Regeneron Genetics Center, Regeneron Pharmaceuticals, Inc., Tarrytown, New York 10591, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chambers</LastName><ForeName>John C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Imperial College Healthcare NHS Trust, London W12 0HS, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cupples</LastName><ForeName>L Adrienne</ForeName><Initials>LA</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dehghan</LastName><ForeName>Abbas</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Erasmus Medical Center, 3000CA Rotterdam/Zuidholland, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Deloukas</LastName><ForeName>Panos</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 21589, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fatemifar</LastName><ForeName>Ghazaleh</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>Caroline</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Harvard Medical School, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Furey</LastName><ForeName>Terrence S</ForeName><Initials>TS</Initials><AffiliationInfo><Affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Franke</LastName><ForeName>Lude</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Han</LastName><ForeName>Jiali</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hunter</LastName><ForeName>David J</ForeName><Initials>DJ</Initials><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karjalainen</LastName><ForeName>Juha</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karpe</LastName><ForeName>Fredrik</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Oxford NIHR Biomedical Research Centre, Oxford OX3 7LJ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaplan</LastName><ForeName>Robert C</ForeName><Initials>RC</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kooner</LastName><ForeName>Jaspal S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Imperial College Healthcare NHS Trust, London W12 0HS, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McCarthy</LastName><ForeName>Mark I</ForeName><Initials>MI</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Oxford NIHR Biomedical Research Centre, Oxford OX3 7LJ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Murabito</LastName><ForeName>Joanne M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, Massachusetts 02118, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>NHLBI's and Boston University's Framingham Heart Study, Framingham, Massachusetts 01702, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Morris</LastName><ForeName>Andrew P</ForeName><Initials>AP</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bishop</LastName><ForeName>Julia A N</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>North</LastName><ForeName>Kari E</ForeName><Initials>KE</Initials><AffiliationInfo><Affiliation>Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7400, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ohlsson</LastName><ForeName>Claes</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ong</LastName><ForeName>Ken K</ForeName><Initials>KK</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>MRC Unit for Lifelong Health and Ageing at UCL, London WC1B 5JU, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prokopenko</LastName><ForeName>Inga</ForeName><Initials>I</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-1624-7457</Identifier><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Richards</LastName><ForeName>J Brent</ForeName><Initials>JB</Initials><AffiliationInfo><Affiliation>Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Twin Research, King's College London, London SE1 1E7, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Endocrinology, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schadt</LastName><ForeName>Eric E</ForeName><Initials>EE</Initials><AffiliationInfo><Affiliation>Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spector</LastName><ForeName>Tim D</ForeName><Initials>TD</Initials><AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Widén</LastName><ForeName>Elisabeth</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Willer</LastName><ForeName>Cristen J</ForeName><Initials>CJ</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-5645-4966</Identifier><AffiliationInfo><Affiliation>Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Jian</ForeName><Initials>J</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-2001-2474</Identifier><AffiliationInfo><Affiliation>Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ingelsson</LastName><ForeName>Erik</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medical Sciences, Molecular Epidemiology, Uppsala University, 751 85 Uppsala, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mohlke</LastName><ForeName>Karen L</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hirschhorn</LastName><ForeName>Joel N</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pospisilik</LastName><ForeName>John Andrew</ForeName><Initials>JA</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-9745-0977</Identifier><AffiliationInfo><Affiliation>Department of Epigenetics, Max Planck Institute of Immunobiology and Epigenetics, D-76108 Freiburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zillikens</LastName><ForeName>M Carola</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lindgren</LastName><ForeName>Cecilia</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Big Data Institute, University of Oxford, Oxford OX3 7LJ, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kilpeläinen</LastName><ForeName>Tuomas Oskari</ForeName><Initials>TO</Initials><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Loos</LastName><ForeName>Ruth J F</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, 10029, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><Agency>British Heart Foundation</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MC_UP_A100_1003</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 DK106236</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 DK072193</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 DK079637</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><Agency>Biotechnology and Biological Sciences Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/J012165/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><Agency>Department of Health</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 DK075787</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_UU_12015/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MC_U106179471</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>K01 HL129892</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_UU_12015/2</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/J010642/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><Agency>Canadian Institutes of Health Research</Agency><Country>Canada</Country></Grant><Grant><GrantID>P30 AG010161</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MC_U106179472</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>IK2 CX000729</GrantID><Acronym>CX</Acronym><Agency>CSRD VA</Agency><Country>United States</Country></Grant><Grant><GrantID>P30 DK020541</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_UU_12013/4</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MC_PC_U127561128</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>U01 DK062370</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><Agency>Arthritis Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 DK089256</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>K01 AR062655</GrantID><Acronym>AR</Acronym><Agency>NIAMS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MR/K006584/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MR/K013351/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>281641</GrantID><Agency>European Research Council</Agency><Country>International</Country></Grant><Grant><GrantID>P30 DK020572</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_UU_12015/5</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><Agency>Chief Scientist Office</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>MC_UU_12011/4</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 HL117078</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>10589</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>02</Month><Day>01</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Nat 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d'Oxford</li><li>Université d'Uppsala</li><li>Université d'Édimbourg</li><li>Université de Caroline du Nord à Chapel Hill</li><li>Université de Groningue</li><li>Université de Leeds</li><li>Université de Londres</li><li>Université de Pittsburgh</li><li>Université de Turku</li><li>Université de Wageningue</li><li>Université de Washington</li><li>Université des sciences et de la médecine de l'Oregon</li><li>École de médecine (Université Washington de Saint-Louis)</li></orgName></list><tree><noCountry><name sortKey="Fatemifar, Ghazaleh" sort="Fatemifar, Ghazaleh" uniqKey="Fatemifar G" first="Ghazaleh" last="Fatemifar">Ghazaleh Fatemifar</name><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H" last="Franco">Oscar H. Franco</name><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Paternoster, Lavinia" sort="Paternoster, Lavinia" uniqKey="Paternoster L" first="Lavinia" last="Paternoster">Lavinia Paternoster</name><name sortKey="S Rensen, Thorkild I A" sort="S Rensen, Thorkild I A" uniqKey="S Rensen T" first="Thorkild I A" last="S Rensen">Thorkild I A. S Rensen</name><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Lu, Yingchang" sort="Lu, Yingchang" uniqKey="Lu Y" first="Yingchang" last="Lu">Yingchang Lu</name></noRegion><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B" last="Borecki">Ingrid B. Borecki</name><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name><name sortKey="Buchkovich, Martin L" sort="Buchkovich, Martin L" uniqKey="Buchkovich M" first="Martin L" last="Buchkovich">Martin L. Buchkovich</name><name sortKey="Buchman, Aron S" sort="Buchman, Aron S" uniqKey="Buchman A" first="Aron S" last="Buchman">Aron S. Buchman</name><name sortKey="Choh, Audrey C" sort="Choh, Audrey C" uniqKey="Choh A" first="Audrey C" last="Choh">Audrey C. Choh</name><name sortKey="Cooper, Richard S" sort="Cooper, Richard S" uniqKey="Cooper R" first="Richard S" last="Cooper">Richard S. Cooper</name><name sortKey="Cummings, Steven R" sort="Cummings, Steven R" uniqKey="Cummings S" first="Steven R" last="Cummings">Steven R. Cummings</name><name sortKey="Cupples, L Adrienne" sort="Cupples, L Adrienne" uniqKey="Cupples L" first="L Adrienne" last="Cupples">L Adrienne Cupples</name><name sortKey="Curran, Joanne E" sort="Curran, Joanne E" uniqKey="Curran J" first="Joanne E" last="Curran">Joanne E. Curran</name><name sortKey="Czerwinski, Stefan A" sort="Czerwinski, Stefan A" uniqKey="Czerwinski S" first="Stefan A" last="Czerwinski">Stefan A. Czerwinski</name><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><name sortKey="Evans, Daniel S" sort="Evans, Daniel S" uniqKey="Evans D" first="Daniel S" last="Evans">Daniel S. Evans</name><name sortKey="Feitosa, Mary F" sort="Feitosa, Mary F" uniqKey="Feitosa M" first="Mary F" last="Feitosa">Mary F. Feitosa</name><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><name sortKey="Fox, Caroline" sort="Fox, Caroline" uniqKey="Fox C" first="Caroline" last="Fox">Caroline Fox</name><name sortKey="Furey, Terrence S" sort="Furey, Terrence S" uniqKey="Furey T" first="Terrence S" last="Furey">Terrence S. Furey</name><name sortKey="Garcia, Melissa E" sort="Garcia, Melissa E" uniqKey="Garcia M" first="Melissa E" last="Garcia">Melissa E. Garcia</name><name sortKey="Han, Jiali" sort="Han, Jiali" uniqKey="Han J" first="Jiali" last="Han">Jiali Han</name><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><name sortKey="Hernandez, Dena" sort="Hernandez, Dena" uniqKey="Hernandez D" first="Dena" last="Hernandez">Dena Hernandez</name><name sortKey="Hirschhorn, Joel N" sort="Hirschhorn, Joel N" uniqKey="Hirschhorn J" first="Joel N" last="Hirschhorn">Joel N. Hirschhorn</name><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><name sortKey="Jordan, Joanne M" sort="Jordan, Joanne M" uniqKey="Jordan J" first="Joanne M" last="Jordan">Joanne M. Jordan</name><name sortKey="Justice, Anne E" sort="Justice, Anne E" uniqKey="Justice A" first="Anne E" last="Justice">Anne E. Justice</name><name sortKey="Kaplan, Robert C" sort="Kaplan, Robert C" uniqKey="Kaplan R" first="Robert C" last="Kaplan">Robert C. Kaplan</name><name sortKey="Kent, Jack W" sort="Kent, Jack W" uniqKey="Kent J" first="Jack W" last="Kent">Jack W. Kent</name><name sortKey="Kiel, Douglas P" sort="Kiel, Douglas P" uniqKey="Kiel D" first="Douglas P" last="Kiel">Douglas P. Kiel</name><name sortKey="Lee, Christine G" sort="Lee, Christine G" uniqKey="Lee C" first="Christine G" last="Lee">Christine G. Lee</name><name sortKey="Li, Xin" sort="Li, Xin" uniqKey="Li X" first="Xin" last="Li">Xin Li</name><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><name sortKey="Liu, Youfang" sort="Liu, Youfang" uniqKey="Liu Y" first="Youfang" last="Liu">Youfang Liu</name><name sortKey="Locke, Adam" sort="Locke, Adam" uniqKey="Locke A" first="Adam" last="Locke">Adam Locke</name><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><name sortKey="Lu, Chen" sort="Lu, Chen" uniqKey="Lu C" first="Chen" last="Lu">Chen Lu</name><name sortKey="Luke, Amy" sort="Luke, Amy" uniqKey="Luke A" first="Amy" last="Luke">Amy Luke</name><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L" last="Mohlke">Karen L. Mohlke</name><name sortKey="Murabito, Joanne M" sort="Murabito, Joanne M" uniqKey="Murabito J" first="Joanne M" last="Murabito">Joanne M. Murabito</name><name sortKey="Na, Jianbo" sort="Na, Jianbo" uniqKey="Na J" first="Jianbo" last="Na">Jianbo Na</name><name sortKey="Nalls, Mike A" sort="Nalls, Mike A" uniqKey="Nalls M" first="Mike A" last="Nalls">Mike A. Nalls</name><name sortKey="Nielson, Carrie M" sort="Nielson, Carrie M" uniqKey="Nielson C" first="Carrie M" last="Nielson">Carrie M. Nielson</name><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R" last="O'Connell">Jeffrey R. O'Connell</name><name sortKey="Orwoll, Eric S" sort="Orwoll, Eric S" uniqKey="Orwoll E" first="Eric S" last="Orwoll">Eric S. Orwoll</name><name sortKey="Palmer, Cameron D" sort="Palmer, Cameron D" uniqKey="Palmer C" first="Cameron D" last="Palmer">Cameron D. Palmer</name><name sortKey="Pers, Tune H" sort="Pers, Tune H" uniqKey="Pers T" first="Tune H" last="Pers">Tune H. Pers</name><name sortKey="Qi, Qibin" sort="Qi, Qibin" uniqKey="Qi Q" first="Qibin" last="Qi">Qibin Qi</name><name sortKey="Rankinen, Tuomo" sort="Rankinen, Tuomo" uniqKey="Rankinen T" first="Tuomo" last="Rankinen">Tuomo Rankinen</name><name sortKey="Rao, D C" sort="Rao, D C" uniqKey="Rao D" first="D C" last="Rao">D C Rao</name><name sortKey="Rice, Treva K" sort="Rice, Treva K" uniqKey="Rice T" first="Treva K" last="Rice">Treva K. Rice</name><name sortKey="Sarzynski, Mark A" sort="Sarzynski, Mark A" uniqKey="Sarzynski M" first="Mark A" last="Sarzynski">Mark A. Sarzynski</name><name sortKey="Schadt, Eric E" sort="Schadt, Eric E" uniqKey="Schadt E" first="Eric E" last="Schadt">Eric E. Schadt</name><name sortKey="Schmidt, Ellen M" sort="Schmidt, Ellen M" uniqKey="Schmidt E" first="Ellen M" last="Schmidt">Ellen M. Schmidt</name><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><name sortKey="Song, Kijoung" sort="Song, Kijoung" uniqKey="Song K" first="Kijoung" last="Song">Kijoung Song</name><name sortKey="Srikanth, Priya" sort="Srikanth, Priya" uniqKey="Srikanth P" first="Priya" last="Srikanth">Priya Srikanth</name><name sortKey="Sung, Yun Ju" sort="Sung, Yun Ju" uniqKey="Sung Y" first="Yun Ju" last="Sung">Yun Ju Sung</name><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><name sortKey="Tayo, Bamidele O" sort="Tayo, Bamidele O" uniqKey="Tayo B" first="Bamidele O" last="Tayo">Bamidele O. Tayo</name><name sortKey="Towne, Bradford" sort="Towne, Bradford" uniqKey="Towne B" first="Bradford" last="Towne">Bradford Towne</name><name sortKey="Tranah, Gregory J" sort="Tranah, Gregory J" uniqKey="Tranah G" first="Gregory J" last="Tranah">Gregory J. Tranah</name><name sortKey="Walker, Mark" sort="Walker, Mark" uniqKey="Walker M" first="Mark" last="Walker">Mark Walker</name><name sortKey="Walker, Ryan W" sort="Walker, Ryan W" uniqKey="Walker R" first="Ryan W" last="Walker">Ryan W. Walker</name><name sortKey="Westra, Harm Jan" sort="Westra, Harm Jan" uniqKey="Westra H" first="Harm-Jan" last="Westra">Harm-Jan Westra</name><name sortKey="White, Charles C" sort="White, Charles C" uniqKey="White C" first="Charles C" last="White">Charles C. White</name><name sortKey="Willer, Cristen J" sort="Willer, Cristen J" uniqKey="Willer C" first="Cristen J" last="Willer">Cristen J. Willer</name><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><name sortKey="Zhang, Mingfeng" sort="Zhang, Mingfeng" uniqKey="Zhang M" first="Mingfeng" last="Zhang">Mingfeng Zhang</name><name sortKey="Zmuda, Joseph M" sort="Zmuda, Joseph M" uniqKey="Zmuda J" first="Joseph M" last="Zmuda">Joseph M. Zmuda</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Day, Felix R" sort="Day, Felix R" uniqKey="Day F" first="Felix R" last="Day">Felix R. Day</name></noRegion><name sortKey="Afzal, Uzma" sort="Afzal, Uzma" uniqKey="Afzal U" first="Uzma" last="Afzal">Uzma Afzal</name><name sortKey="Bataille, Veronique" sort="Bataille, Veronique" uniqKey="Bataille V" first="Veronique" last="Bataille">Veronique Bataille</name><name sortKey="Bertram, Lars" sort="Bertram, Lars" uniqKey="Bertram L" first="Lars" last="Bertram">Lars Bertram</name><name sortKey="Bishop, D Timothy" sort="Bishop, D Timothy" uniqKey="Bishop D" first="D Timothy" last="Bishop">D Timothy Bishop</name><name sortKey="Bishop, Julia A N" sort="Bishop, Julia A N" uniqKey="Bishop J" first="Julia A N" last="Bishop">Julia A N. Bishop</name><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><name sortKey="Drong, Alexander W" sort="Drong, Alexander W" uniqKey="Drong A" first="Alexander W" last="Drong">Alexander W. Drong</name><name sortKey="Falchi, Mario" sort="Falchi, Mario" uniqKey="Falchi M" first="Mario" last="Falchi">Mario Falchi</name><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G" last="Forouhi">Nita G. Forouhi</name><name sortKey="Hastie, Nicholas" sort="Hastie, Nicholas" uniqKey="Hastie N" first="Nicholas" last="Hastie">Nicholas Hastie</name><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><name sortKey="Hingorani, Aroon" sort="Hingorani, Aroon" uniqKey="Hingorani A" first="Aroon" last="Hingorani">Aroon Hingorani</name><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name><name sortKey="Iles, Mark M" sort="Iles, Mark M" uniqKey="Iles M" first="Mark M" last="Iles">Mark M. Iles</name><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><name sortKey="Karpe, Fredrik" sort="Karpe, Fredrik" uniqKey="Karpe F" first="Fredrik" last="Karpe">Fredrik Karpe</name><name sortKey="Kilpel Inen, Tuomas Oskari" sort="Kilpel Inen, Tuomas Oskari" uniqKey="Kilpel Inen T" first="Tuomas Oskari" last="Kilpel Inen">Tuomas Oskari Kilpel Inen</name><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><name sortKey="Lindgren, Cecilia" sort="Lindgren, Cecilia" uniqKey="Lindgren C" first="Cecilia" last="Lindgren">Cecilia Lindgren</name><name sortKey="Loh, Marie" sort="Loh, Marie" uniqKey="Loh M" first="Marie" last="Loh">Marie Loh</name><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><name sortKey="Menni, Cristina" sort="Menni, Cristina" uniqKey="Menni C" first="Cristina" last="Menni">Cristina Menni</name><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P" last="Morris">Andrew P. Morris</name><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K" last="Ong">Ken K. Ong</name><name sortKey="Oozageer, Laticia" sort="Oozageer, Laticia" uniqKey="Oozageer L" first="Laticia" last="Oozageer">Laticia Oozageer</name><name sortKey="Osmond, Clive" sort="Osmond, Clive" uniqKey="Osmond C" first="Clive" last="Osmond">Clive Osmond</name><name sortKey="Pascoe, Laura" sort="Pascoe, Laura" uniqKey="Pascoe L" first="Laura" last="Pascoe">Laura Pascoe</name><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R B" last="Perry">John R B. Perry</name><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><name sortKey="Sanna, Marianna" sort="Sanna, Marianna" uniqKey="Sanna M" first="Marianna" last="Sanna">Marianna Sanna</name><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A" last="Scott">Robert A. Scott</name><name sortKey="Scott, William R" sort="Scott, William R" uniqKey="Scott W" first="William R" last="Scott">William R. Scott</name><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><name sortKey="Wild, Sarah" sort="Wild, Sarah" uniqKey="Wild S" first="Sarah" last="Wild">Sarah Wild</name><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name></country><country name="Suède"><region name="Svealand"><name sortKey="Gustafsson, Stefan" sort="Gustafsson, Stefan" uniqKey="Gustafsson S" first="Stefan" last="Gustafsson">Stefan Gustafsson</name></region><name sortKey="Cederholm, Tommy" sort="Cederholm, Tommy" uniqKey="Cederholm T" first="Tommy" last="Cederholm">Tommy Cederholm</name><name sortKey="Hedman, Sa K" sort="Hedman, Sa K" uniqKey="Hedman " first=" Sa K" last="Hedman"> Sa K. Hedman</name><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><name sortKey="Michaelsson, Karl" sort="Michaelsson, Karl" uniqKey="Michaelsson K" first="Karl" last="Michaëlsson">Karl Michaëlsson</name><name sortKey="Ohlsson, Claes" sort="Ohlsson, Claes" uniqKey="Ohlsson C" first="Claes" last="Ohlsson">Claes Ohlsson</name><name sortKey="Shungin, Dmitry" sort="Shungin, Dmitry" uniqKey="Shungin D" first="Dmitry" last="Shungin">Dmitry Shungin</name><name sortKey="Vandenput, Liesbeth" sort="Vandenput, Liesbeth" uniqKey="Vandenput L" first="Liesbeth" last="Vandenput">Liesbeth Vandenput</name></country><country name="Finlande"><region name="Uusimaa"><name sortKey="Cousminer, Diana L" sort="Cousminer, Diana L" uniqKey="Cousminer D" first="Diana L" last="Cousminer">Diana L. Cousminer</name></region><name sortKey="Borodulin, Katja" sort="Borodulin, Katja" uniqKey="Borodulin K" first="Katja" last="Borodulin">Katja Borodulin</name><name sortKey="Eklund, Niina" sort="Eklund, Niina" uniqKey="Eklund N" first="Niina" last="Eklund">Niina Eklund</name><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><name sortKey="Forsen, Tom" sort="Forsen, Tom" uniqKey="Forsen T" first="Tom" last="Forsen">Tom Forsen</name><name sortKey="Havulinna, Aki S" sort="Havulinna, Aki S" uniqKey="Havulinna A" first="Aki S" last="Havulinna">Aki S. Havulinna</name><name sortKey="Heliovaara, Markku" sort="Heliovaara, Markku" uniqKey="Heliovaara M" first="Markku" last="Heliövaara">Markku Heliövaara</name><name sortKey="Jousilahti, Pekka" sort="Jousilahti, Pekka" uniqKey="Jousilahti P" first="Pekka" last="Jousilahti">Pekka Jousilahti</name><name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><name sortKey="Kajantie, Eero" sort="Kajantie, Eero" uniqKey="Kajantie E" first="Eero" last="Kajantie">Eero Kajantie</name><name sortKey="Knekt, Paul B" sort="Knekt, Paul B" uniqKey="Knekt P" first="Paul B" last="Knekt">Paul B. 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Evans</name></noRegion><name sortKey="Vinkhuyzen, Anna A E" sort="Vinkhuyzen, Anna A E" uniqKey="Vinkhuyzen A" first="Anna A E" last="Vinkhuyzen">Anna A E. 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Ried</name><name sortKey="Spira, Dominik" sort="Spira, Dominik" uniqKey="Spira D" first="Dominik" last="Spira">Dominik Spira</name><name sortKey="Steinhagen Thiessen, Elisabeth" sort="Steinhagen Thiessen, Elisabeth" uniqKey="Steinhagen Thiessen E" first="Elisabeth" last="Steinhagen-Thiessen">Elisabeth Steinhagen-Thiessen</name><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Ahluwalia, Tarunveer Singh" sort="Ahluwalia, Tarunveer Singh" uniqKey="Ahluwalia T" first="Tarunveer Singh" last="Ahluwalia">Tarunveer Singh Ahluwalia</name></region><name sortKey="Grarup, Niels" sort="Grarup, Niels" uniqKey="Grarup N" first="Niels" last="Grarup">Niels Grarup</name><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name><name sortKey="J Rgensen, Torben" sort="J Rgensen, Torben" uniqKey="J Rgensen T" first="Torben" last="J Rgensen">Torben J Rgensen</name><name sortKey="Linneberg, Allan" sort="Linneberg, Allan" uniqKey="Linneberg A" first="Allan" last="Linneberg">Allan Linneberg</name><name sortKey="Pedersen, Oluf" sort="Pedersen, Oluf" uniqKey="Pedersen O" first="Oluf" last="Pedersen">Oluf Pedersen</name></country><country name="Pays-Bas"><region name="Groningue (province)"><name sortKey="Bakker, Stephan J L" sort="Bakker, Stephan J L" uniqKey="Bakker S" first="Stephan J L" last="Bakker">Stephan J L. 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Mckenzie</name></country><country name="Islande"><noRegion><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name></noRegion></country><country name="Suisse"><region name="Canton de Vaud"><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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