Opioid-Sparing Effect of Ketamine in Children: A Meta-Analysis and Trial Sequential Analysis of Published Studies.
Identifieur interne : 001954 ( PubMed/Checkpoint ); précédent : 001953; suivant : 001955Opioid-Sparing Effect of Ketamine in Children: A Meta-Analysis and Trial Sequential Analysis of Published Studies.
Auteurs : Daphnée Michelet [France] ; Julie Hilly [France] ; Alia Skhiri [France] ; Rachida Abdat [France] ; Thierno Diallo [France] ; Christopher Brasher [Australie] ; Souhayl Dahmani [France]Source :
- Paediatric drugs [ 1179-2019 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
- traitement médicamenteux : Douleur postopératoire.
- usage thérapeutique : Analgésiques morphiniques, Kétamine.
- épidémiologie : Vomissements et nausées postopératoires.
- Enfant, Humains.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Analgesics, Opioid, Ketamine.
- drug therapy : Pain, Postoperative.
- epidemiology : Postoperative Nausea and Vomiting.
- Child, Humans.
Abstract
Reducing postoperative opioid consumption is a priority given its impact upon recovery, and the efficacy of ketamine as an opioid-sparing agent in children is debated. The goal of this study was to update a previous meta-analysis on the postoperative opioid-sparing effect of ketamine, adding trial sequential analysis (TSA) and four new studies.
DOI: 10.1007/s40272-016-0196-y
PubMed: 27688125
Affiliations:
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pubmed:27688125Le document en format XML
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sortKey="Dahmani, Souhayl" sort="Dahmani, Souhayl" uniqKey="Dahmani S" first="Souhayl" last="Dahmani">Souhayl Dahmani</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France. souhayl.dahmani@rdb.aphp.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27688125</idno><idno type="pmid">27688125</idno><idno type="doi">10.1007/s40272-016-0196-y</idno><idno type="wicri:Area/PubMed/Corpus">001448</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" 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type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Hilly, Julie" sort="Hilly, Julie" uniqKey="Hilly J" first="Julie" last="Hilly">Julie Hilly</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Skhiri, Alia" sort="Skhiri, Alia" uniqKey="Skhiri A" first="Alia" last="Skhiri">Alia Skhiri</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Abdat, Rachida" sort="Abdat, Rachida" uniqKey="Abdat R" first="Rachida" last="Abdat">Rachida Abdat</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Diallo, Thierno" sort="Diallo, Thierno" uniqKey="Diallo T" first="Thierno" last="Diallo">Thierno Diallo</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Brasher, Christopher" sort="Brasher, Christopher" uniqKey="Brasher C" first="Christopher" last="Brasher">Christopher Brasher</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Dahmani, Souhayl" sort="Dahmani, Souhayl" uniqKey="Dahmani S" first="Souhayl" last="Dahmani">Souhayl Dahmani</name><affiliation wicri:level="3"><nlm:affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France. souhayl.dahmani@rdb.aphp.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j">Paediatric drugs</title><idno type="eISSN">1179-2019</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Analgesics, Opioid (therapeutic use)</term><term>Child</term><term>Humans</term><term>Ketamine (therapeutic use)</term><term>Pain, Postoperative (drug therapy)</term><term>Postoperative Nausea and Vomiting (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analgésiques morphiniques (usage thérapeutique)</term><term>Douleur postopératoire (traitement médicamenteux)</term><term>Enfant</term><term>Humains</term><term>Kétamine (usage thérapeutique)</term><term>Vomissements et nausées postopératoires (épidémiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Analgesics, Opioid</term><term>Ketamine</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Pain, Postoperative</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Postoperative Nausea and Vomiting</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Douleur postopératoire</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Analgésiques morphiniques</term><term>Kétamine</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Vomissements et nausées postopératoires</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Enfant</term><term>Humains</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Reducing postoperative opioid consumption is a priority given its impact upon recovery, and the efficacy of ketamine as an opioid-sparing agent in children is debated. The goal of this study was to update a previous meta-analysis on the postoperative opioid-sparing effect of ketamine, adding trial sequential analysis (TSA) and four new studies.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27688125</PMID><DateCreated><Year>2016</Year><Month>09</Month><Day>30</Day></DateCreated><DateCompleted><Year>2016</Year><Month>12</Month><Day>13</Day></DateCompleted><DateRevised><Year>2017</Year><Month>11</Month><Day>14</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1179-2019</ISSN><JournalIssue CitedMedium="Internet"><Volume>18</Volume><Issue>6</Issue><PubDate><Year>2016</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Paediatric drugs</Title><ISOAbbreviation>Paediatr Drugs</ISOAbbreviation></Journal><ArticleTitle>Opioid-Sparing Effect of Ketamine in Children: A Meta-Analysis and Trial Sequential Analysis of Published Studies.</ArticleTitle><Pagination><MedlinePgn>421-433</MedlinePgn></Pagination><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Reducing postoperative opioid consumption is a priority given its impact upon recovery, and the efficacy of ketamine as an opioid-sparing agent in children is debated. The goal of this study was to update a previous meta-analysis on the postoperative opioid-sparing effect of ketamine, adding trial sequential analysis (TSA) and four new studies.</AbstractText><AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">A comprehensive literature search was conducted to identify clinical trials that examined ketamine as a perioperative opioid-sparing agent in children and infants. Outcomes measured were postoperative opioid consumption to 48 h (primary outcome: postoperative opioid consumption to 24 h), postoperative pain intensity, postoperative nausea and vomiting and psychotomimetic symptoms. The data were combined to calculate the pooled mean difference, odds ratios or standard mean differences. In addition to this classical meta-analysis approach, a TSA was performed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Eleven articles were identified, with four added to seven from the previous meta-analysis. Ketamine did not exhibit a global postoperative opioid-sparing effect to 48 postoperative hours, nor did it decrease postoperative pain intensity. This result was confirmed using TSA, which found a lack of power to draw any conclusion regarding the primary outcome of this meta-analysis (postoperative opioid consumption to 24 h). Ketamine did not increase the prevalence of either postoperative nausea and vomiting or psychotomimetic complications.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This meta-analysis did not find a postoperative opioid-sparing effect of ketamine. According to the TSA, this negative result might involve a lack of power of this meta-analysis. Further studies are needed in order to assess the postoperative opioid-sparing effects of ketamine in children.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Michelet</LastName><ForeName>Daphnée</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Paris Diderot University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hilly</LastName><ForeName>Julie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Paris Diderot University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Skhiri</LastName><ForeName>Alia</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Paris Diderot University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abdat</LastName><ForeName>Rachida</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Paris Diderot University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Diallo</LastName><ForeName>Thierno</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Paris Diderot University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brasher</LastName><ForeName>Christopher</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dahmani</LastName><ForeName>Souhayl</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Anesthesia and Intensive Care, Robert Debre University Hospital, Paris, France. souhayl.dahmani@rdb.aphp.fr.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Paris Diderot University, Paris, France. souhayl.dahmani@rdb.aphp.fr.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>DHU PROTECT, INSERM U1141, Robert Debre University Hospital, Paris, France. souhayl.dahmani@rdb.aphp.fr.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Anesthesiology, Intensive Care and Pain Management, Robert Debre Hospital, 48 Bd Sérurier, 75019, Paris, France. souhayl.dahmani@rdb.aphp.fr.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Paediatr Drugs</MedlineTA><NlmUniqueID>100883685</NlmUniqueID><ISSNLinking>1174-5878</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000701">Analgesics, Opioid</NameOfSubstance></Chemical><Chemical><RegistryNumber>690G0D6V8H</RegistryNumber><NameOfSubstance UI="D007649">Ketamine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Stat Med. 1997 Apr 15;16(7):753-68</RefSource><PMID Version="1">9131763</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Int J Clin Pharmacol Ther. 2007 Mar;45(3):155-60</RefSource><PMID Version="1">17416110</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Anaesthesiol. 2015 Feb;32(2):85-7</RefSource><PMID Version="1">25536187</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Opioid Manag. 2013 Sep-Oct;9(5):379-88</RefSource><PMID Version="1">24353050</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Paediatr Anaesth. 2003 Jun;13(5):413-21</RefSource><PMID Version="1">12791115</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 1997 Mar 1;349(9052):599-603</RefSource><PMID Version="1">9057731</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Anaesthesiol. 2010 Jan;27(1):47-52</RefSource><PMID Version="1">19535988</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMJ. 2001 Jul 14;323(7304):101-5</RefSource><PMID Version="1">11451790</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Anesth Analg. 2012 Feb;114(2):393-406</RefSource><PMID Version="1">22104069</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Anesth Pain Med. 2012 Fall;2(2):85-9</RefSource><PMID Version="1">24223344</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Paediatr Anaesth. 2008 Aug;18(8):708-14</RefSource><PMID Version="1">18613930</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Anesthesiology. 1987 Jun;66(6):832-4</RefSource><PMID Version="1">2884900</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Dis Child Fetal Neonatal Ed. 2001 Jul;85(1):F36-41</RefSource><PMID Version="1">11420320</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Anaesth. 1983 Nov;55(11):1107-11</RefSource><PMID Version="1">6639827</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cochrane Database Syst Rev. 2006 Jan 25;(1):CD004603</RefSource><PMID Version="1">16437490</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Acta Anaesthesiol Belg. 2003;54(3):217-22</RefSource><PMID Version="1">14598618</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Curr Opin Anaesthesiol. 2006 Oct;19(5):556-61</RefSource><PMID Version="1">16960491</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Can J Anaesth. 2016 Mar;63(3):311-25</RefSource><PMID Version="1">26659198</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Paediatr Anaesth. 2003 Jun;13(5):422-6</RefSource><PMID Version="1">12791116</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Anaesth. 1979 Dec;51(12):1167-73</RefSource><PMID Version="1">526385</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Stat Med. 2000 Nov 30;19(22):3127-31</RefSource><PMID Version="1">11113947</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Pharmacol Res. 2012 Apr;65(4):411-29</RefSource><PMID Version="1">22311381</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Paediatr Anaesth. 2011 Oct;21(10):1009-14</RefSource><PMID Version="1">21575100</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Pain. 2005 Jan;113(1-2):61-70</RefSource><PMID Version="1">15621365</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Paediatr Anaesth. 2014 Jun;24(6):582-90</RefSource><PMID Version="1">24809838</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Paediatr Anaesth. 2011 Jun;21(6):636-52</RefSource><PMID Version="1">21447047</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Epidemiol. 2009 Oct;62(10):e1-34</RefSource><PMID Version="1">19631507</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Spine (Phila Pa 1976). 2017 Mar;42(5):E304-E312</RefSource><PMID Version="1">27398889</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Med Res Methodol. 2005 Apr 20;5:13</RefSource><PMID Version="1">15840177</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMJ. 1997 Sep 13;315(7109):629-34</RefSource><PMID Version="1">9310563</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Pain Palliat Care Pharmacother. 2011;25(3):219-30</RefSource><PMID Version="1">21834699</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Pain. 2010 Aug;150(2):257-67</RefSource><PMID Version="1">20471751</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Anesth Analg. 2008 Oct;107(4):1170-5</RefSource><PMID Version="1">18806023</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Med Sci Monit. 2009 Oct;15(10):CR539-543</RefSource><PMID Version="1">19789514</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Stat Med. 2008 Feb 28;27(5):625-50</RefSource><PMID Version="1">17590884</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000701" MajorTopicYN="N">Analgesics, Opioid</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007649" MajorTopicYN="N">Ketamine</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010149" MajorTopicYN="N">Pain, Postoperative</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020250" MajorTopicYN="N">Postoperative Nausea and Vomiting</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>10</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>12</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>10</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27688125</ArticleId><ArticleId IdType="doi">10.1007/s40272-016-0196-y</ArticleId><ArticleId IdType="pii">10.1007/s40272-016-0196-y</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>France</li></country><region><li>Victoria (État)</li><li>Île-de-France</li></region><settlement><li>Melbourne</li><li>Paris</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Michelet, Daphnee" sort="Michelet, Daphnee" uniqKey="Michelet D" first="Daphnée" last="Michelet">Daphnée Michelet</name></region><name sortKey="Abdat, Rachida" sort="Abdat, Rachida" uniqKey="Abdat R" first="Rachida" last="Abdat">Rachida Abdat</name><name sortKey="Dahmani, Souhayl" sort="Dahmani, Souhayl" uniqKey="Dahmani S" first="Souhayl" last="Dahmani">Souhayl Dahmani</name><name sortKey="Diallo, Thierno" sort="Diallo, Thierno" uniqKey="Diallo T" first="Thierno" last="Diallo">Thierno Diallo</name><name sortKey="Hilly, Julie" sort="Hilly, Julie" uniqKey="Hilly J" first="Julie" last="Hilly">Julie Hilly</name><name sortKey="Skhiri, Alia" sort="Skhiri, Alia" uniqKey="Skhiri A" first="Alia" last="Skhiri">Alia Skhiri</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Brasher, Christopher" sort="Brasher, Christopher" uniqKey="Brasher C" first="Christopher" last="Brasher">Christopher Brasher</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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