SYN-JEM: A Quantitative Job-Exposure Matrix for Five Lung Carcinogens.
Identifieur interne : 001716 ( PubMed/Checkpoint ); précédent : 001715; suivant : 001717SYN-JEM: A Quantitative Job-Exposure Matrix for Five Lung Carcinogens.
Auteurs : Susan Peters [Pays-Bas] ; Roel Vermeulen [Pays-Bas] ; Lützen Portengen [Pays-Bas] ; Ann Olsson [France] ; Benjamin Kendzia [Allemagne] ; Raymond Vincent [France] ; Barbara Savary [France] ; Jérôme Lavoué [Canada] ; Domenico Cavallo [Italie] ; Andrea Cattaneo [Italie] ; Dario Mirabelli [Italie] ; Nils Plato [Suède] ; Joelle Fevotte [France] ; Beate Pesch [Allemagne] ; Thomas Brüning [Allemagne] ; Kurt Straif [France] ; Hans Kromhout [Pays-Bas]Source :
- The Annals of occupational hygiene [ 1475-3162 ] ; 2016.
Descripteurs français
- KwdFr :
- Amiante (analyse), Canada, Cancérogènes (analyse), Chrome (analyse), Europe, Exposition professionnelle (analyse), Humains, Hydrocarbures aromatiques polycycliques (analyse), Nickel (analyse), Polluants atmosphériques d'origine professionnelle (analyse), Silice (analyse), Tumeurs du poumon (étiologie).
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Air Pollutants, Occupational, Asbestos, Carcinogens, Chromium, Nickel, Polycyclic Aromatic Hydrocarbons, Silicon Dioxide.
- analysis : Occupational Exposure.
- etiology : Lung Neoplasms.
- Canada, Europe, Humans.
Abstract
The use of measurement data in occupational exposure assessment allows more quantitative analyses of possible exposure-response relations. We describe a quantitative exposure assessment approach for five lung carcinogens (i.e. asbestos, chromium-VI, nickel, polycyclic aromatic hydrocarbons (by its proxy benzo(a)pyrene (BaP)) and respirable crystalline silica). A quantitative job-exposure matrix (JEM) was developed based on statistical modeling of large quantities of personal measurements.
DOI: 10.1093/annhyg/mew034
PubMed: 27286764
Affiliations:
- Allemagne, Canada, France, Italie, Pays-Bas, Suède
- Auvergne-Rhône-Alpes, Grand Est, Lorraine (région), Piémont, Rhône-Alpes, Svealand, Utrecht (province)
- Lyon, Nancy, Stockholm, Turin, Utrecht, Vandœuvre-lès-Nancy
- Université d'Utrecht
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pubmed:27286764Le document en format XML
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Savary</name><affiliation wicri:level="3"><nlm:affiliation>6.Institut National de Recherche et de Sécurité, Vandoeuvre lès Nancy, France;</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>6.Institut National de Recherche et de Sécurité, Vandoeuvre lès Nancy</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Lorraine (région)</region><settlement type="city">Vandœuvre-lès-Nancy</settlement><settlement type="city" wicri:auto="agglo">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Lavoue, Jerome" sort="Lavoue, Jerome" uniqKey="Lavoue J" first="Jérôme" last="Lavoué">Jérôme Lavoué</name><affiliation wicri:level="1"><nlm:affiliation>7.Research Centre of University of Montreal Hospital Research Centre, Canada;</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>7.Research Centre of University of Montreal Hospital Research Centre</wicri:regionArea></affiliation></author><author><name sortKey="Cavallo, Domenico" sort="Cavallo, Domenico" uniqKey="Cavallo D" first="Domenico" last="Cavallo">Domenico Cavallo</name><affiliation wicri:level="1"><nlm:affiliation>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como, Italy;</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como</wicri:regionArea><wicri:noRegion>Como</wicri:noRegion></affiliation></author><author><name sortKey="Cattaneo, Andrea" sort="Cattaneo, Andrea" uniqKey="Cattaneo A" first="Andrea" last="Cattaneo">Andrea Cattaneo</name><affiliation wicri:level="1"><nlm:affiliation>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como, Italy;</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como</wicri:regionArea><wicri:noRegion>Como</wicri:noRegion></affiliation></author><author><name sortKey="Mirabelli, Dario" sort="Mirabelli, Dario" uniqKey="Mirabelli D" first="Dario" last="Mirabelli">Dario Mirabelli</name><affiliation wicri:level="3"><nlm:affiliation>9.Cancer Epidemiology Unit, CPO-Piemonte and University of Turin, Turin, Italy;</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>9.Cancer Epidemiology Unit, CPO-Piemonte and University of Turin, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Plato, Nils" sort="Plato, Nils" uniqKey="Plato N" first="Nils" last="Plato">Nils Plato</name><affiliation wicri:level="3"><nlm:affiliation>10.The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden;</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>10.The Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Fevotte, Joelle" sort="Fevotte, Joelle" uniqKey="Fevotte J" first="Joelle" last="Fevotte">Joelle Fevotte</name><affiliation wicri:level="1"><nlm:affiliation>11.Département santé travail, Institut de veille sanitaire, St Maurice, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>11.Département santé travail, Institut de veille sanitaire, St Maurice</wicri:regionArea><wicri:noRegion>St Maurice</wicri:noRegion><wicri:noRegion>St Maurice</wicri:noRegion></affiliation></author><author><name sortKey="Pesch, Beate" sort="Pesch, Beate" uniqKey="Pesch B" first="Beate" last="Pesch">Beate Pesch</name><affiliation wicri:level="1"><nlm:affiliation>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum, Germany;</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><nlm:affiliation>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum, Germany;</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, 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University of Western Australia, Perth</wicri:regionArea><orgName type="university">Université d'Utrecht</orgName><placeName><settlement type="city">Utrecht</settlement><region nuts="2">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Vermeulen, Roel" sort="Vermeulen, Roel" uniqKey="Vermeulen R" first="Roel" last="Vermeulen">Roel Vermeulen</name><affiliation wicri:level="4"><nlm:affiliation>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands; 3.Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands;</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands; 3.Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region><settlement type="city">Utrecht</settlement></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Portengen, Lutzen" sort="Portengen, Lutzen" uniqKey="Portengen L" first="Lützen" last="Portengen">Lützen Portengen</name><affiliation wicri:level="4"><nlm:affiliation>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands;</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region><settlement type="city">Utrecht</settlement></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Olsson, Ann" sort="Olsson, Ann" uniqKey="Olsson A" first="Ann" last="Olsson">Ann Olsson</name><affiliation wicri:level="3"><nlm:affiliation>4.International Agency for Research on Cancer, Lyon, France;</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>4.International Agency for Research on Cancer, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Kendzia, Benjamin" sort="Kendzia, Benjamin" uniqKey="Kendzia B" first="Benjamin" last="Kendzia">Benjamin Kendzia</name><affiliation wicri:level="1"><nlm:affiliation>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum, Germany;</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Vincent, Raymond" sort="Vincent, Raymond" uniqKey="Vincent R" first="Raymond" last="Vincent">Raymond Vincent</name><affiliation wicri:level="3"><nlm:affiliation>6.Institut National de Recherche et de Sécurité, Vandoeuvre lès Nancy, France;</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>6.Institut National de Recherche et de Sécurité, Vandoeuvre lès Nancy</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Lorraine (région)</region><settlement type="city">Vandœuvre-lès-Nancy</settlement><settlement type="city" wicri:auto="agglo">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Savary, Barbara" sort="Savary, Barbara" uniqKey="Savary B" first="Barbara" last="Savary">Barbara Savary</name><affiliation wicri:level="3"><nlm:affiliation>6.Institut National de Recherche et de Sécurité, Vandoeuvre lès Nancy, France;</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>6.Institut National de Recherche et de Sécurité, Vandoeuvre lès Nancy</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Lorraine (région)</region><settlement type="city">Vandœuvre-lès-Nancy</settlement><settlement type="city" wicri:auto="agglo">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Lavoue, Jerome" sort="Lavoue, Jerome" uniqKey="Lavoue J" first="Jérôme" last="Lavoué">Jérôme Lavoué</name><affiliation wicri:level="1"><nlm:affiliation>7.Research Centre of University of Montreal Hospital Research Centre, Canada;</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>7.Research Centre of University of Montreal Hospital Research Centre</wicri:regionArea></affiliation></author><author><name sortKey="Cavallo, Domenico" sort="Cavallo, Domenico" uniqKey="Cavallo D" first="Domenico" last="Cavallo">Domenico Cavallo</name><affiliation wicri:level="1"><nlm:affiliation>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como, Italy;</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como</wicri:regionArea><wicri:noRegion>Como</wicri:noRegion></affiliation></author><author><name sortKey="Cattaneo, Andrea" sort="Cattaneo, Andrea" uniqKey="Cattaneo A" first="Andrea" last="Cattaneo">Andrea Cattaneo</name><affiliation wicri:level="1"><nlm:affiliation>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como, Italy;</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como</wicri:regionArea><wicri:noRegion>Como</wicri:noRegion></affiliation></author><author><name sortKey="Mirabelli, Dario" sort="Mirabelli, Dario" uniqKey="Mirabelli D" first="Dario" last="Mirabelli">Dario Mirabelli</name><affiliation wicri:level="3"><nlm:affiliation>9.Cancer Epidemiology Unit, CPO-Piemonte and University of Turin, Turin, Italy;</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>9.Cancer Epidemiology Unit, CPO-Piemonte and University of Turin, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Plato, Nils" sort="Plato, Nils" uniqKey="Plato N" first="Nils" last="Plato">Nils Plato</name><affiliation wicri:level="3"><nlm:affiliation>10.The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden;</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>10.The Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Fevotte, Joelle" sort="Fevotte, Joelle" uniqKey="Fevotte J" first="Joelle" last="Fevotte">Joelle Fevotte</name><affiliation wicri:level="1"><nlm:affiliation>11.Département santé travail, Institut de veille sanitaire, St Maurice, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>11.Département santé travail, Institut de veille sanitaire, St Maurice</wicri:regionArea><wicri:noRegion>St Maurice</wicri:noRegion><wicri:noRegion>St Maurice</wicri:noRegion></affiliation></author><author><name sortKey="Pesch, Beate" sort="Pesch, Beate" uniqKey="Pesch B" first="Beate" last="Pesch">Beate Pesch</name><affiliation wicri:level="1"><nlm:affiliation>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum, Germany;</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><nlm:affiliation>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum, Germany;</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Straif, Kurt" sort="Straif, Kurt" uniqKey="Straif K" first="Kurt" last="Straif">Kurt Straif</name><affiliation wicri:level="3"><nlm:affiliation>4.International Agency for Research on Cancer, Lyon, France;</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>4.International Agency for Research on Cancer, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Kromhout, Hans" sort="Kromhout, Hans" uniqKey="Kromhout H" first="Hans" last="Kromhout">Hans Kromhout</name><affiliation wicri:level="4"><nlm:affiliation>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands;</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region><settlement type="city">Utrecht</settlement></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author></analytic><series><title level="j">The Annals of occupational hygiene</title><idno type="eISSN">1475-3162</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Air Pollutants, Occupational (analysis)</term><term>Asbestos (analysis)</term><term>Canada</term><term>Carcinogens (analysis)</term><term>Chromium (analysis)</term><term>Europe</term><term>Humans</term><term>Lung Neoplasms (etiology)</term><term>Nickel (analysis)</term><term>Occupational Exposure (analysis)</term><term>Polycyclic Aromatic Hydrocarbons (analysis)</term><term>Silicon Dioxide (analysis)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Amiante (analyse)</term><term>Canada</term><term>Cancérogènes (analyse)</term><term>Chrome (analyse)</term><term>Europe</term><term>Exposition professionnelle (analyse)</term><term>Humains</term><term>Hydrocarbures aromatiques polycycliques (analyse)</term><term>Nickel (analyse)</term><term>Polluants atmosphériques d'origine professionnelle (analyse)</term><term>Silice (analyse)</term><term>Tumeurs du poumon (étiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Air Pollutants, Occupational</term><term>Asbestos</term><term>Carcinogens</term><term>Chromium</term><term>Nickel</term><term>Polycyclic Aromatic Hydrocarbons</term><term>Silicon Dioxide</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Amiante</term><term>Cancérogènes</term><term>Chrome</term><term>Exposition professionnelle</term><term>Hydrocarbures aromatiques polycycliques</term><term>Nickel</term><term>Polluants atmosphériques d'origine professionnelle</term><term>Silice</term></keywords><keywords scheme="MESH" qualifier="analysis" xml:lang="en"><term>Occupational Exposure</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lung Neoplasms</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Tumeurs du poumon</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Canada</term><term>Europe</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Canada</term><term>Europe</term><term>Humains</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The use of measurement data in occupational exposure assessment allows more quantitative analyses of possible exposure-response relations. We describe a quantitative exposure assessment approach for five lung carcinogens (i.e. asbestos, chromium-VI, nickel, polycyclic aromatic hydrocarbons (by its proxy benzo(a)pyrene (BaP)) and respirable crystalline silica). A quantitative job-exposure matrix (JEM) was developed based on statistical modeling of large quantities of personal measurements.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27286764</PMID><DateCreated><Year>2016</Year><Month>07</Month><Day>30</Day></DateCreated><DateCompleted><Year>2017</Year><Month>09</Month><Day>12</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>12</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1475-3162</ISSN><JournalIssue CitedMedium="Internet"><Volume>60</Volume><Issue>7</Issue><PubDate><Year>2016</Year><Month>Aug</Month></PubDate></JournalIssue><Title>The Annals of occupational hygiene</Title><ISOAbbreviation>Ann Occup Hyg</ISOAbbreviation></Journal><ArticleTitle>SYN-JEM: A Quantitative Job-Exposure Matrix for Five Lung Carcinogens.</ArticleTitle><Pagination><MedlinePgn>795-811</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/annhyg/mew034</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The use of measurement data in occupational exposure assessment allows more quantitative analyses of possible exposure-response relations. We describe a quantitative exposure assessment approach for five lung carcinogens (i.e. asbestos, chromium-VI, nickel, polycyclic aromatic hydrocarbons (by its proxy benzo(a)pyrene (BaP)) and respirable crystalline silica). A quantitative job-exposure matrix (JEM) was developed based on statistical modeling of large quantities of personal measurements.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Empirical linear models were developed using personal occupational exposure measurements (n = 102306) from Europe and Canada, as well as auxiliary information like job (industry), year of sampling, region, an a priori exposure rating of each job (none, low, and high exposed), sampling and analytical methods, and sampling duration. The model outcomes were used to create a JEM with a quantitative estimate of the level of exposure by job, year, and region.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Decreasing time trends were observed for all agents between the 1970s and 2009, ranging from -1.2% per year for personal BaP and nickel exposures to -10.7% for asbestos (in the time period before an asbestos ban was implemented). Regional differences in exposure concentrations (adjusted for measured jobs, years of measurement, and sampling method and duration) varied by agent, ranging from a factor 3.3 for chromium-VI up to a factor 10.5 for asbestos.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">We estimated time-, job-, and region-specific exposure levels for four (asbestos, chromium-VI, nickel, and RCS) out of five considered lung carcinogens. Through statistical modeling of large amounts of personal occupational exposure measurement data we were able to derive a quantitative JEM to be used in community-based studies.</AbstractText><CopyrightInformation>© The Author 2016. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Peters</LastName><ForeName>Susan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands; 2.Occupational Respiratory Epidemiology, School of Population Health, University of Western Australia, Perth, Australia; h.kromhout@uu.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vermeulen</LastName><ForeName>Roel</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands; 3.Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Portengen</LastName><ForeName>Lützen</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olsson</LastName><ForeName>Ann</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>4.International Agency for Research on Cancer, Lyon, France;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kendzia</LastName><ForeName>Benjamin</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum, Germany;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vincent</LastName><ForeName>Raymond</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>6.Institut National de Recherche et de Sécurité, Vandoeuvre lès Nancy, France;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Savary</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>6.Institut National de Recherche et de Sécurité, Vandoeuvre lès Nancy, France;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lavoué</LastName><ForeName>Jérôme</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>7.Research Centre of University of Montreal Hospital Research Centre, Canada;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cavallo</LastName><ForeName>Domenico</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como, Italy;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cattaneo</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>8.Department of Science and High Technology, Università degli Studi dell'Insubria, Como, Italy;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mirabelli</LastName><ForeName>Dario</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>9.Cancer Epidemiology Unit, CPO-Piemonte and University of Turin, Turin, Italy;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Plato</LastName><ForeName>Nils</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>10.The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fevotte</LastName><ForeName>Joelle</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>11.Département santé travail, Institut de veille sanitaire, St Maurice, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pesch</LastName><ForeName>Beate</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum, Germany;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brüning</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>5.Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Rurh-Universität Bochum, Bochum, Germany;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Straif</LastName><ForeName>Kurt</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>4.International Agency for Research on Cancer, Lyon, France;</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kromhout</LastName><ForeName>Hans</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>1.Environmental Epidemiology Division, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands;</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>06</Month><Day>09</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Ann Occup Hyg</MedlineTA><NlmUniqueID>0203526</NlmUniqueID><ISSNLinking>0003-4878</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000395">Air Pollutants, Occupational</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002273">Carcinogens</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011084">Polycyclic Aromatic Hydrocarbons</NameOfSubstance></Chemical><Chemical><RegistryNumber>0R0008Q3JB</RegistryNumber><NameOfSubstance UI="D002857">Chromium</NameOfSubstance></Chemical><Chemical><RegistryNumber>1332-21-4</RegistryNumber><NameOfSubstance UI="D001194">Asbestos</NameOfSubstance></Chemical><Chemical><RegistryNumber>7631-86-9</RegistryNumber><NameOfSubstance UI="D012822">Silicon Dioxide</NameOfSubstance></Chemical><Chemical><RegistryNumber>7OV03QG267</RegistryNumber><NameOfSubstance UI="D009532">Nickel</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000395" MajorTopicYN="N">Air Pollutants, Occupational</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001194" MajorTopicYN="N">Asbestos</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N">Canada</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002273" MajorTopicYN="N">Carcinogens</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002857" MajorTopicYN="N">Chromium</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005060" MajorTopicYN="N">Europe</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008175" MajorTopicYN="N">Lung Neoplasms</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009532" MajorTopicYN="N">Nickel</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016273" MajorTopicYN="N">Occupational Exposure</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011084" MajorTopicYN="N">Polycyclic Aromatic Hydrocarbons</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012822" MajorTopicYN="N">Silicon Dioxide</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">asbestos exposure</Keyword><Keyword MajorTopicYN="N">chromium</Keyword><Keyword MajorTopicYN="N">exposure assessment</Keyword><Keyword MajorTopicYN="N">exposure assessment—mixed models</Keyword><Keyword MajorTopicYN="N">nickel</Keyword><Keyword MajorTopicYN="N">polycyclic aromatic hydrocarbons</Keyword><Keyword MajorTopicYN="N">respirable crystalline silica</Keyword><Keyword MajorTopicYN="N">retrospective exposure assessment</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>10</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>05</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>6</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>6</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27286764</ArticleId><ArticleId IdType="pii">mew034</ArticleId><ArticleId IdType="doi">10.1093/annhyg/mew034</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Canada</li><li>France</li><li>Italie</li><li>Pays-Bas</li><li>Suède</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Grand Est</li><li>Lorraine (région)</li><li>Piémont</li><li>Rhône-Alpes</li><li>Svealand</li><li>Utrecht (province)</li></region><settlement><li>Lyon</li><li>Nancy</li><li>Stockholm</li><li>Turin</li><li>Utrecht</li><li>Vandœuvre-lès-Nancy</li></settlement><orgName><li>Université d'Utrecht</li></orgName></list><tree><country name="Pays-Bas"><region name="Utrecht (province)"><name sortKey="Peters, Susan" sort="Peters, Susan" uniqKey="Peters S" first="Susan" last="Peters">Susan Peters</name></region><name sortKey="Kromhout, Hans" sort="Kromhout, Hans" uniqKey="Kromhout H" first="Hans" last="Kromhout">Hans Kromhout</name><name sortKey="Portengen, Lutzen" sort="Portengen, Lutzen" uniqKey="Portengen L" first="Lützen" last="Portengen">Lützen Portengen</name><name sortKey="Vermeulen, Roel" sort="Vermeulen, Roel" uniqKey="Vermeulen R" first="Roel" last="Vermeulen">Roel Vermeulen</name></country><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Olsson, Ann" sort="Olsson, Ann" uniqKey="Olsson A" first="Ann" last="Olsson">Ann Olsson</name></region><name sortKey="Fevotte, Joelle" sort="Fevotte, Joelle" uniqKey="Fevotte J" first="Joelle" last="Fevotte">Joelle Fevotte</name><name sortKey="Savary, Barbara" sort="Savary, Barbara" uniqKey="Savary B" first="Barbara" last="Savary">Barbara Savary</name><name sortKey="Straif, Kurt" sort="Straif, Kurt" uniqKey="Straif K" first="Kurt" last="Straif">Kurt Straif</name><name sortKey="Vincent, Raymond" sort="Vincent, Raymond" uniqKey="Vincent R" first="Raymond" last="Vincent">Raymond Vincent</name></country><country name="Allemagne"><noRegion><name sortKey="Kendzia, Benjamin" sort="Kendzia, Benjamin" uniqKey="Kendzia B" first="Benjamin" last="Kendzia">Benjamin Kendzia</name></noRegion><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><name sortKey="Pesch, Beate" sort="Pesch, Beate" uniqKey="Pesch B" first="Beate" last="Pesch">Beate Pesch</name></country><country name="Canada"><noRegion><name sortKey="Lavoue, Jerome" sort="Lavoue, Jerome" uniqKey="Lavoue J" first="Jérôme" last="Lavoué">Jérôme Lavoué</name></noRegion></country><country name="Italie"><noRegion><name sortKey="Cavallo, Domenico" sort="Cavallo, Domenico" uniqKey="Cavallo D" first="Domenico" last="Cavallo">Domenico Cavallo</name></noRegion><name sortKey="Cattaneo, Andrea" sort="Cattaneo, Andrea" uniqKey="Cattaneo A" first="Andrea" last="Cattaneo">Andrea Cattaneo</name><name sortKey="Mirabelli, Dario" sort="Mirabelli, Dario" uniqKey="Mirabelli D" first="Dario" last="Mirabelli">Dario Mirabelli</name></country><country name="Suède"><region name="Svealand"><name sortKey="Plato, Nils" sort="Plato, Nils" uniqKey="Plato N" first="Nils" last="Plato">Nils Plato</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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