Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis.
Identifieur interne : 001419 ( PubMed/Checkpoint ); précédent : 001418; suivant : 001420Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis.
Auteurs : Lawrence P. Park [États-Unis] ; Vivian H. Chu [États-Unis] ; Gail Peterson [États-Unis] ; Athanasios Skoutelis [Grèce] ; Tatjana Lejko-Zupa [Slovénie] ; Emilio Bouza [Espagne] ; Pierre Tattevin [France] ; Gilbert Habib [France] ; Ren Tan [Australie] ; Javier Gonzalez [Colombie] ; Javier Altclas [Argentine] ; Jameela Edathodu [Arabie saoudite] ; Claudio Querido Fortes [Brésil] ; Rinaldo Focaccia Siciliano [Brésil] ; Orathai Pachirat [Thaïlande] ; Souha Kanj [Liban] ; Andrew Wang [États-Unis]Source :
- Journal of the American Heart Association [ 2047-9980 ] ; 2016.
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Abstract
Host factors and complications have been associated with higher mortality in infective endocarditis (IE). We sought to develop and validate a model of clinical characteristics to predict 6-month mortality in IE.
DOI: 10.1161/JAHA.115.003016
PubMed: 27091179
Affiliations:
- Arabie saoudite, Argentine, Australie, Brésil, Colombie, Espagne, France, Grèce, Liban, Slovénie, Thaïlande, États-Unis
- Attique (région), Caroline du Nord, Communauté de Madrid, Provence-Alpes-Côte d'Azur, Région Bretagne, Texas, État de Rio de Janeiro, État de São Paulo
- Athènes, Madrid, Marseille, Rennes, Rio de Janeiro, São Paulo
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Chu</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center, Durham, NC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Peterson, Gail" sort="Peterson, Gail" uniqKey="Peterson G" first="Gail" last="Peterson">Gail Peterson</name><affiliation wicri:level="2"><nlm:affiliation>UT-Southwestern Medical Center, Dallas, TX.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>UT-Southwestern Medical Center, Dallas</wicri:cityArea></affiliation></author><author><name sortKey="Skoutelis, Athanasios" sort="Skoutelis, Athanasios" uniqKey="Skoutelis A" first="Athanasios" last="Skoutelis">Athanasios Skoutelis</name><affiliation wicri:level="3"><nlm:affiliation>5th Department of Medicine and 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sortKey="Habib, Gilbert" sort="Habib, Gilbert" uniqKey="Habib G" first="Gilbert" last="Habib">Gilbert Habib</name><affiliation wicri:level="3"><nlm:affiliation>Faculté de Médecine de Marseille, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine de Marseille, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Tan, Ren" sort="Tan, Ren" uniqKey="Tan R" first="Ren" last="Tan">Ren Tan</name><affiliation wicri:level="1"><nlm:affiliation>The Canberra Hospital, Woden, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The Canberra Hospital, Woden</wicri:regionArea><wicri:noRegion>Woden</wicri:noRegion></affiliation></author><author><name sortKey="Gonzalez, Javier" sort="Gonzalez, Javier" uniqKey="Gonzalez J" first="Javier" last="Gonzalez">Javier Gonzalez</name><affiliation wicri:level="1"><nlm:affiliation>Clinica Cardio VID, Medellín, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Clinica Cardio VID, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Altclas, Javier" sort="Altclas, Javier" uniqKey="Altclas J" first="Javier" last="Altclas">Javier Altclas</name><affiliation wicri:level="1"><nlm:affiliation>Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Sanatorio de la Trinidad Mitre, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Edathodu, Jameela" sort="Edathodu, Jameela" uniqKey="Edathodu J" first="Jameela" last="Edathodu">Jameela Edathodu</name><affiliation wicri:level="1"><nlm:affiliation>King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>King Faisal Specialist Hospital & Research Center, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Fortes, Claudio Querido" sort="Fortes, Claudio Querido" uniqKey="Fortes C" first="Claudio Querido" last="Fortes">Claudio Querido Fortes</name><affiliation wicri:level="3"><nlm:affiliation>Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Universidade Federal do Rio de Janeiro, Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Siciliano, Rinaldo Focaccia" sort="Siciliano, Rinaldo Focaccia" uniqKey="Siciliano R" first="Rinaldo Focaccia" last="Siciliano">Rinaldo Focaccia Siciliano</name><affiliation wicri:level="3"><nlm:affiliation>Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Pachirat, Orathai" sort="Pachirat, Orathai" uniqKey="Pachirat O" first="Orathai" last="Pachirat">Orathai Pachirat</name><affiliation wicri:level="1"><nlm:affiliation>Khon Kaen University, Khon Kaen, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Khon Kaen University, Khon Kaen</wicri:regionArea><wicri:noRegion>Khon Kaen</wicri:noRegion></affiliation></author><author><name sortKey="Kanj, Souha" sort="Kanj, Souha" uniqKey="Kanj S" first="Souha" 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Park</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center, Durham, NC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Chu, Vivian H" sort="Chu, Vivian H" uniqKey="Chu V" first="Vivian H" last="Chu">Vivian H. Chu</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center, Durham, NC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Peterson, Gail" sort="Peterson, Gail" uniqKey="Peterson G" first="Gail" last="Peterson">Gail Peterson</name><affiliation wicri:level="2"><nlm:affiliation>UT-Southwestern Medical Center, Dallas, TX.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>UT-Southwestern Medical Center, Dallas</wicri:cityArea></affiliation></author><author><name sortKey="Skoutelis, Athanasios" sort="Skoutelis, Athanasios" uniqKey="Skoutelis A" first="Athanasios" last="Skoutelis">Athanasios Skoutelis</name><affiliation wicri:level="3"><nlm:affiliation>5th Department of Medicine and Infectious Diseases Unit, "Evangelismos" General Hospital, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>5th Department of Medicine and Infectious Diseases Unit, "Evangelismos" General Hospital, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Lejko Zupa, Tatjana" sort="Lejko Zupa, Tatjana" uniqKey="Lejko Zupa T" first="Tatjana" last="Lejko-Zupa">Tatjana Lejko-Zupa</name><affiliation wicri:level="1"><nlm:affiliation>Medical Centre Ljublijana, Ljublijana, Slovenia.</nlm:affiliation><country xml:lang="fr">Slovénie</country><wicri:regionArea>Medical Centre Ljublijana, Ljublijana</wicri:regionArea><wicri:noRegion>Ljublijana</wicri:noRegion></affiliation></author><author><name sortKey="Bouza, Emilio" sort="Bouza, Emilio" uniqKey="Bouza E" first="Emilio" last="Bouza">Emilio Bouza</name><affiliation wicri:level="3"><nlm:affiliation>Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Tattevin, Pierre" sort="Tattevin, Pierre" uniqKey="Tattevin P" first="Pierre" last="Tattevin">Pierre Tattevin</name><affiliation wicri:level="3"><nlm:affiliation>Maladies Infectieuses et Réanimation Médicale, Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Maladies Infectieuses et Réanimation Médicale, Rennes</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Habib, Gilbert" sort="Habib, Gilbert" uniqKey="Habib G" first="Gilbert" last="Habib">Gilbert Habib</name><affiliation wicri:level="3"><nlm:affiliation>Faculté de Médecine de Marseille, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Faculté de Médecine de Marseille, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Tan, Ren" sort="Tan, Ren" uniqKey="Tan R" first="Ren" last="Tan">Ren Tan</name><affiliation wicri:level="1"><nlm:affiliation>The Canberra Hospital, Woden, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The Canberra Hospital, Woden</wicri:regionArea><wicri:noRegion>Woden</wicri:noRegion></affiliation></author><author><name sortKey="Gonzalez, Javier" sort="Gonzalez, Javier" uniqKey="Gonzalez J" first="Javier" last="Gonzalez">Javier Gonzalez</name><affiliation wicri:level="1"><nlm:affiliation>Clinica Cardio VID, Medellín, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Clinica Cardio VID, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Altclas, Javier" sort="Altclas, Javier" uniqKey="Altclas J" first="Javier" last="Altclas">Javier Altclas</name><affiliation wicri:level="1"><nlm:affiliation>Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Sanatorio de la Trinidad Mitre, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Edathodu, Jameela" sort="Edathodu, Jameela" uniqKey="Edathodu J" first="Jameela" last="Edathodu">Jameela Edathodu</name><affiliation wicri:level="1"><nlm:affiliation>King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>King Faisal Specialist Hospital & Research Center, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Fortes, Claudio Querido" sort="Fortes, Claudio Querido" uniqKey="Fortes C" first="Claudio Querido" last="Fortes">Claudio Querido Fortes</name><affiliation wicri:level="3"><nlm:affiliation>Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Universidade Federal do Rio de Janeiro, Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Siciliano, Rinaldo Focaccia" sort="Siciliano, Rinaldo Focaccia" uniqKey="Siciliano R" first="Rinaldo Focaccia" last="Siciliano">Rinaldo Focaccia Siciliano</name><affiliation wicri:level="3"><nlm:affiliation>Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Pachirat, Orathai" sort="Pachirat, Orathai" uniqKey="Pachirat O" first="Orathai" last="Pachirat">Orathai Pachirat</name><affiliation wicri:level="1"><nlm:affiliation>Khon Kaen University, Khon Kaen, Thailand.</nlm:affiliation><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Khon Kaen University, Khon Kaen</wicri:regionArea><wicri:noRegion>Khon Kaen</wicri:noRegion></affiliation></author><author><name sortKey="Kanj, Souha" sort="Kanj, Souha" uniqKey="Kanj S" first="Souha" last="Kanj">Souha Kanj</name><affiliation wicri:level="1"><nlm:affiliation>American University of Beirut Medical Center, Beirut, Lebanon.</nlm:affiliation><country xml:lang="fr">Liban</country><wicri:regionArea>American University of Beirut Medical Center, Beirut</wicri:regionArea><wicri:noRegion>Beirut</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Andrew" sort="Wang, Andrew" uniqKey="Wang A" first="Andrew" last="Wang">Andrew Wang</name><affiliation wicri:level="1"><nlm:affiliation>Duke University Medical Center, Durham, NC a.wang@duke.edu a.wang@dm.duke.edu.</nlm:affiliation><country wicri:rule="url">États-Unis</country><wicri:regionArea>Duke University Medical Center, Durham</wicri:regionArea><wicri:noRegion>Durham</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of the American Heart Association</title><idno type="eISSN">2047-9980</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Endocarditis (mortality)</term><term>Female</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Male</term><term>Middle Aged</term><term>Models, Statistical</term><term>Propensity Score</term><term>Registries</term><term>Reproducibility of Results</term><term>Risk Assessment</term><term>Risk Factors</term><term>Sensitivity and Specificity</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Endocardite (mortalité)</term><term>Enregistrements</term><term>Estimation de Kaplan-Meier</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Modèles statistiques</term><term>Mâle</term><term>Reproductibilité des résultats</term><term>Score de propension</term><term>Sensibilité et spécificité</term><term>Sujet âgé</term><term>Évaluation des risques</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Endocarditis</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Endocardite</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Male</term><term>Middle Aged</term><term>Models, Statistical</term><term>Propensity Score</term><term>Registries</term><term>Reproducibility of Results</term><term>Risk Assessment</term><term>Risk Factors</term><term>Sensitivity and Specificity</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enregistrements</term><term>Estimation de Kaplan-Meier</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Modèles statistiques</term><term>Mâle</term><term>Reproductibilité des résultats</term><term>Score de propension</term><term>Sensibilité et spécificité</term><term>Sujet âgé</term><term>Évaluation des risques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Host factors and complications have been associated with higher mortality in infective endocarditis (IE). We sought to develop and validate a model of clinical characteristics to predict 6-month mortality in IE.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27091179</PMID><DateCreated><Year>2016</Year><Month>04</Month><Day>19</Day></DateCreated><DateCompleted><Year>2016</Year><Month>12</Month><Day>22</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>20</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2047-9980</ISSN><JournalIssue CitedMedium="Internet"><Volume>5</Volume><Issue>4</Issue><PubDate><Year>2016</Year><Month>Apr</Month><Day>18</Day></PubDate></JournalIssue><Title>Journal of the American Heart Association</Title><ISOAbbreviation>J Am Heart Assoc</ISOAbbreviation></Journal><ArticleTitle>Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis.</ArticleTitle><Pagination><MedlinePgn>e003016</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1161/JAHA.115.003016</ELocationID><ELocationID EIdType="pii" ValidYN="Y">e003016</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Host factors and complications have been associated with higher mortality in infective endocarditis (IE). We sought to develop and validate a model of clinical characteristics to predict 6-month mortality in IE.</AbstractText><AbstractText Label="METHODS AND RESULTS" NlmCategory="RESULTS">Using a large multinational prospective registry of definite IE (International Collaboration on Endocarditis [ICE]-Prospective Cohort Study [PCS], 2000-2006, n=4049), a model to predict 6-month survival was developed by Cox proportional hazards modeling with inverse probability weighting for surgery treatment and was internally validated by the bootstrapping method. This model was externally validated in an independent prospective registry (ICE-PLUS, 2008-2012, n=1197). The 6-month mortality was 971 of 4049 (24.0%) in the ICE-PCS cohort and 342 of 1197 (28.6%) in the ICE-PLUS cohort. Surgery during the index hospitalization was performed in 48.1% and 54.0% of the cohorts, respectively. In the derivation model, variables related to host factors (age, dialysis), IE characteristics (prosthetic or nosocomial IE, causative organism, left-sided valve vegetation), and IE complications (severe heart failure, stroke, paravalvular complication, and persistent bacteremia) were independently associated with 6-month mortality, and surgery was associated with a lower risk of mortality (Harrell's C statistic 0.715). In the validation model, these variables had similar hazard ratios (Harrell's C statistic 0.682), with a similar, independent benefit of surgery (hazard ratio 0.74, 95% CI 0.62-0.89). A simplified risk model was developed by weight adjustment of these variables.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Six-month mortality after IE is ≈25% and is predicted by host factors, IE characteristics, and IE complications. Surgery during the index hospitalization is associated with lower mortality but is performed less frequently in the highest risk patients. A simplified risk model may be used to identify specific risk subgroups in IE.</AbstractText><CopyrightInformation>© 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Park</LastName><ForeName>Lawrence P</ForeName><Initials>LP</Initials><AffiliationInfo><Affiliation>Duke University Medical Center, Durham, NC.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chu</LastName><ForeName>Vivian H</ForeName><Initials>VH</Initials><AffiliationInfo><Affiliation>Duke University Medical Center, Durham, NC.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peterson</LastName><ForeName>Gail</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>UT-Southwestern Medical Center, Dallas, TX.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Skoutelis</LastName><ForeName>Athanasios</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>5th Department of Medicine and Infectious Diseases Unit, "Evangelismos" General Hospital, Athens, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lejko-Zupa</LastName><ForeName>Tatjana</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Medical Centre Ljublijana, Ljublijana, Slovenia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bouza</LastName><ForeName>Emilio</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Hospital General Universitario Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tattevin</LastName><ForeName>Pierre</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Maladies Infectieuses et Réanimation Médicale, Rennes, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Habib</LastName><ForeName>Gilbert</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Faculté de Médecine de Marseille, Marseille, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tan</LastName><ForeName>Ren</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>The Canberra Hospital, Woden, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gonzalez</LastName><ForeName>Javier</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Clinica Cardio VID, Medellín, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Altclas</LastName><ForeName>Javier</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Edathodu</LastName><ForeName>Jameela</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fortes</LastName><ForeName>Claudio Querido</ForeName><Initials>CQ</Initials><AffiliationInfo><Affiliation>Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Siciliano</LastName><ForeName>Rinaldo Focaccia</ForeName><Initials>RF</Initials><AffiliationInfo><Affiliation>Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pachirat</LastName><ForeName>Orathai</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Khon Kaen University, Khon Kaen, Thailand.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kanj</LastName><ForeName>Souha</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>American University of Beirut Medical Center, Beirut, Lebanon.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Duke University Medical Center, Durham, NC a.wang@duke.edu a.wang@dm.duke.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>International Collaboration on Endocarditis (ICE) Investigators</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>04</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Am Heart Assoc</MedlineTA><NlmUniqueID>101580524</NlmUniqueID><ISSNLinking>2047-9980</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Circulation. 2014 Nov 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Jan;141(1):98-106.e1-2</RefSource><PMID Version="1">21168017</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004696" MajorTopicYN="N">Endocarditis</DescriptorName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053208" MajorTopicYN="N">Kaplan-Meier Estimate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle 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H</ForeName><Initials>CH</Initials></Investigator><Investigator ValidYN="Y"><LastName>Chu</LastName><ForeName>Vivian</ForeName><Initials>V</Initials></Investigator><Investigator ValidYN="Y"><LastName>Corey</LastName><ForeName>G Ralph</ForeName><Initials>GR</Initials></Investigator><Investigator ValidYN="Y"><LastName>Durack</LastName><ForeName>David T</ForeName><Initials>DT</Initials></Investigator><Investigator ValidYN="Y"><LastName>Eykyn</LastName><ForeName>Susannah</ForeName><Initials>S</Initials></Investigator><Investigator ValidYN="Y"><LastName>Fowler</LastName><ForeName>Vance G</ForeName><Initials>VG</Initials><Suffix>Jr</Suffix></Investigator><Investigator ValidYN="Y"><LastName>Hoen</LastName><ForeName>Bruno</ForeName><Initials>B</Initials></Investigator><Investigator ValidYN="Y"><LastName>Miró</LastName><ForeName>José M</ForeName><Initials>JM</Initials></Investigator><Investigator ValidYN="Y"><LastName>Moreillon</LastName><ForeName>Phillipe</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>Olaison</LastName><ForeName>Lars</ForeName><Initials>L</Initials></Investigator><Investigator ValidYN="Y"><LastName>Raoult</LastName><ForeName>Didier</ForeName><Initials>D</Initials></Investigator><Investigator ValidYN="Y"><LastName>Rubinstein</LastName><ForeName>Ethan</ForeName><Initials>E</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sexton</LastName><ForeName>Daniel J</ForeName><Initials>DJ</Initials></Investigator></InvestigatorList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>4</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>4</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>12</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27091179</ArticleId><ArticleId IdType="pii">JAHA.115.003016</ArticleId><ArticleId IdType="doi">10.1161/JAHA.115.003016</ArticleId><ArticleId IdType="pmc">PMC4859286</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Arabie saoudite</li><li>Argentine</li><li>Australie</li><li>Brésil</li><li>Colombie</li><li>Espagne</li><li>France</li><li>Grèce</li><li>Liban</li><li>Slovénie</li><li>Thaïlande</li><li>États-Unis</li></country><region><li>Attique (région)</li><li>Caroline du Nord</li><li>Communauté de Madrid</li><li>Provence-Alpes-Côte d'Azur</li><li>Région Bretagne</li><li>Texas</li><li>État de Rio de Janeiro</li><li>État de São Paulo</li></region><settlement><li>Athènes</li><li>Madrid</li><li>Marseille</li><li>Rennes</li><li>Rio de Janeiro</li><li>São Paulo</li></settlement></list><tree><country name="États-Unis"><region name="Caroline du Nord"><name sortKey="Park, Lawrence P" sort="Park, Lawrence P" uniqKey="Park L" first="Lawrence P" last="Park">Lawrence P. Park</name></region><name sortKey="Chu, Vivian H" sort="Chu, Vivian H" uniqKey="Chu V" first="Vivian H" last="Chu">Vivian H. Chu</name><name sortKey="Peterson, Gail" sort="Peterson, Gail" uniqKey="Peterson G" first="Gail" last="Peterson">Gail Peterson</name><name sortKey="Wang, Andrew" sort="Wang, Andrew" uniqKey="Wang A" first="Andrew" last="Wang">Andrew Wang</name></country><country name="Grèce"><region name="Attique (région)"><name sortKey="Skoutelis, Athanasios" sort="Skoutelis, Athanasios" uniqKey="Skoutelis A" first="Athanasios" last="Skoutelis">Athanasios Skoutelis</name></region></country><country name="Slovénie"><noRegion><name sortKey="Lejko Zupa, Tatjana" sort="Lejko Zupa, Tatjana" uniqKey="Lejko Zupa T" first="Tatjana" last="Lejko-Zupa">Tatjana Lejko-Zupa</name></noRegion></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Bouza, Emilio" sort="Bouza, Emilio" uniqKey="Bouza E" first="Emilio" last="Bouza">Emilio Bouza</name></region></country><country name="France"><region name="Région Bretagne"><name sortKey="Tattevin, Pierre" sort="Tattevin, Pierre" uniqKey="Tattevin P" first="Pierre" last="Tattevin">Pierre Tattevin</name></region><name sortKey="Habib, Gilbert" sort="Habib, Gilbert" uniqKey="Habib G" first="Gilbert" last="Habib">Gilbert Habib</name></country><country name="Australie"><noRegion><name sortKey="Tan, Ren" sort="Tan, Ren" uniqKey="Tan R" first="Ren" last="Tan">Ren Tan</name></noRegion></country><country name="Colombie"><noRegion><name sortKey="Gonzalez, Javier" sort="Gonzalez, Javier" uniqKey="Gonzalez J" first="Javier" last="Gonzalez">Javier Gonzalez</name></noRegion></country><country name="Argentine"><noRegion><name sortKey="Altclas, Javier" sort="Altclas, Javier" uniqKey="Altclas J" first="Javier" last="Altclas">Javier Altclas</name></noRegion></country><country name="Arabie saoudite"><noRegion><name sortKey="Edathodu, Jameela" sort="Edathodu, Jameela" uniqKey="Edathodu J" first="Jameela" last="Edathodu">Jameela Edathodu</name></noRegion></country><country name="Brésil"><region name="État de Rio de Janeiro"><name sortKey="Fortes, Claudio Querido" sort="Fortes, Claudio Querido" uniqKey="Fortes C" first="Claudio Querido" last="Fortes">Claudio Querido Fortes</name></region><name sortKey="Siciliano, Rinaldo Focaccia" sort="Siciliano, Rinaldo Focaccia" uniqKey="Siciliano R" first="Rinaldo Focaccia" last="Siciliano">Rinaldo Focaccia Siciliano</name></country><country name="Thaïlande"><noRegion><name sortKey="Pachirat, Orathai" sort="Pachirat, Orathai" uniqKey="Pachirat O" first="Orathai" last="Pachirat">Orathai Pachirat</name></noRegion></country><country name="Liban"><noRegion><name sortKey="Kanj, Souha" sort="Kanj, Souha" uniqKey="Kanj S" first="Souha" last="Kanj">Souha Kanj</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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