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A multicenter international registry of redo per-oral endoscopic myotomy (POEM) after failed POEM.

Identifieur interne : 001304 ( PubMed/Checkpoint ); précédent : 001303; suivant : 001305

A multicenter international registry of redo per-oral endoscopic myotomy (POEM) after failed POEM.

Auteurs : Amy Tyberg [États-Unis] ; Stefan Seewald [Suisse] ; Reem Z. Sharaiha [États-Unis] ; Guadalupe Martinez [Mexique] ; Amit P. Desai [États-Unis] ; Nikhil A. Kumta [États-Unis] ; Arnon Lambroza [États-Unis] ; Amrita Sethi [États-Unis] ; Kevin M. Reavis [États-Unis] ; Ketisha Deroche [États-Unis] ; Monica Gaidhane [États-Unis] ; Michael Talbot [Australie] ; Payal Saxena [Australie] ; Felipe Zamarripa [Mexique] ; Maximilien Barret [France] ; Nicholas Eleftheriadis [Japon] ; Valerio Balassone [Japon] ; Haruhiro Inoue [Japon] ; Michel Kahaleh [États-Unis]

Source :

RBID : pubmed:27756611

Abstract

Per-oral endoscopic myotomy (POEM) has become an accepted treatment for patients with achalasia. Despite its excellent efficacy rate of greater than 80%, a small percentage of patients remain symptomatic after the procedure. Limited data exist as to the best management for recurrence of symptoms after POEM. We present the first international, multicenter experience on the efficacy and safety of a repeat POEM in the management of achalasia.

DOI: 10.1016/j.gie.2016.10.015
PubMed: 27756611


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pubmed:27756611

Le document en format XML

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<name sortKey="Deroche, Ketisha" sort="Deroche, Ketisha" uniqKey="Deroche K" first="Ketisha" last="Deroche">Ketisha Deroche</name>
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<name sortKey="Gaidhane, Monica" sort="Gaidhane, Monica" uniqKey="Gaidhane M" first="Monica" last="Gaidhane">Monica Gaidhane</name>
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<name sortKey="Talbot, Michael" sort="Talbot, Michael" uniqKey="Talbot M" first="Michael" last="Talbot">Michael Talbot</name>
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<name sortKey="Saxena, Payal" sort="Saxena, Payal" uniqKey="Saxena P" first="Payal" last="Saxena">Payal Saxena</name>
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<country xml:lang="fr">Australie</country>
<wicri:regionArea>Division of Gastroenterology, Royal Prince Alfred Hospital, Camperdown, New South Wales</wicri:regionArea>
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<name sortKey="Zamarripa, Felipe" sort="Zamarripa, Felipe" uniqKey="Zamarripa F" first="Felipe" last="Zamarripa">Felipe Zamarripa</name>
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<nlm:affiliation>Gastroenterology, Juarez Hospital, Mexico City, Mexico.</nlm:affiliation>
<country xml:lang="fr">Mexique</country>
<wicri:regionArea>Gastroenterology, Juarez Hospital, Mexico City</wicri:regionArea>
<wicri:noRegion>Mexico City</wicri:noRegion>
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<name sortKey="Barret, Maximilien" sort="Barret, Maximilien" uniqKey="Barret M" first="Maximilien" last="Barret">Maximilien Barret</name>
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<nlm:affiliation>Department of Gastroenterology, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Gastroenterology, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
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<name sortKey="Eleftheriadis, Nicholas" sort="Eleftheriadis, Nicholas" uniqKey="Eleftheriadis N" first="Nicholas" last="Eleftheriadis">Nicholas Eleftheriadis</name>
<affiliation wicri:level="3">
<nlm:affiliation>Digestive Disease Center, Showa University Koto-Toyosu Hospital, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Digestive Disease Center, Showa University Koto-Toyosu Hospital, Tokyo</wicri:regionArea>
<placeName>
<settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
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<name sortKey="Balassone, Valerio" sort="Balassone, Valerio" uniqKey="Balassone V" first="Valerio" last="Balassone">Valerio Balassone</name>
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<name sortKey="Inoue, Haruhiro" sort="Inoue, Haruhiro" uniqKey="Inoue H" first="Haruhiro" last="Inoue">Haruhiro Inoue</name>
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<nlm:affiliation>Digestive Disease Center, Showa University Koto-Toyosu Hospital, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Digestive Disease Center, Showa University Koto-Toyosu Hospital, Tokyo</wicri:regionArea>
<placeName>
<settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Kahaleh, Michel" sort="Kahaleh, Michel" uniqKey="Kahaleh M" first="Michel" last="Kahaleh">Michel Kahaleh</name>
<affiliation wicri:level="2">
<nlm:affiliation>Division of Gastroenterology & Hepatology, Weill Cornell Medicine, New York, New York, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Gastroenterology & Hepatology, Weill Cornell Medicine, New York, New York</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Gastrointestinal endoscopy</title>
<idno type="eISSN">1097-6779</idno>
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<date when="2017" type="published">2017</date>
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<div type="abstract" xml:lang="en">Per-oral endoscopic myotomy (POEM) has become an accepted treatment for patients with achalasia. Despite its excellent efficacy rate of greater than 80%, a small percentage of patients remain symptomatic after the procedure. Limited data exist as to the best management for recurrence of symptoms after POEM. We present the first international, multicenter experience on the efficacy and safety of a repeat POEM in the management of achalasia.</div>
</front>
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<MedlineCitation Status="In-Process" Owner="NLM">
<PMID Version="1">27756611</PMID>
<DateCreated>
<Year>2016</Year>
<Month>10</Month>
<Day>19</Day>
</DateCreated>
<DateRevised>
<Year>2017</Year>
<Month>05</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1097-6779</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>85</Volume>
<Issue>6</Issue>
<PubDate>
<Year>2017</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Gastrointestinal endoscopy</Title>
<ISOAbbreviation>Gastrointest. Endosc.</ISOAbbreviation>
</Journal>
<ArticleTitle>A multicenter international registry of redo per-oral endoscopic myotomy (POEM) after failed POEM.</ArticleTitle>
<Pagination>
<MedlinePgn>1208-1211</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S0016-5107(16)30672-1</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.gie.2016.10.015</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND AND AIMS" NlmCategory="OBJECTIVE">Per-oral endoscopic myotomy (POEM) has become an accepted treatment for patients with achalasia. Despite its excellent efficacy rate of greater than 80%, a small percentage of patients remain symptomatic after the procedure. Limited data exist as to the best management for recurrence of symptoms after POEM. We present the first international, multicenter experience on the efficacy and safety of a repeat POEM in the management of achalasia.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Patients who underwent a redo POEM from 15 centers in 9 countries were included in a dedicated registry. Technical success was defined as successful completion of a second myotomy. Clinical success was defined as an Eckardt score of less than or equal to 3 after the second myotomy. Adverse events including anesthesia-related, operative, and postoperative adverse events were recorded.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Forty-six patients were included in the study. The average age was 49.3 ± 16.78 years. Twenty (45%) patients were male. The mean pre-redo-POEM Eckardt score was 4.3 ± 2.48. Technical success was achieved in 46 (100%) patients. Clinical success was achieved in 41 patients (85%). The average post-POEM Eckardt score was 1.64 ± 1.67, with a significant difference of 2.58 (P < .00001). Eight patients (17%) had adverse events consisting of procedural bleeding, all managed endoscopically. There were no deaths. No POEMs were aborted or required surgical conversion or assistance.</AbstractText>
<AbstractText Label="DISCUSSION" NlmCategory="CONCLUSIONS">For patients with persistent symptoms after POEM, repeat POEM appears to be an efficacious and safe technique. Further randomized trials comparing redo POEM versus Heller should be considered. (Clinical trial registration number: NCT02162589.).</AbstractText>
<CopyrightInformation>Copyright © 2017 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
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<LastName>Tyberg</LastName>
<ForeName>Amy</ForeName>
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<Affiliation>Division of Gastroenterology & Hepatology, Weill Cornell Medicine, New York, New York, USA.</Affiliation>
</AffiliationInfo>
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<LastName>Seewald</LastName>
<ForeName>Stefan</ForeName>
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<Affiliation>GastroZentrum Hirslanden, Klinik Hirslanden, Zurich, Switzerland.</Affiliation>
</AffiliationInfo>
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<LastName>Sharaiha</LastName>
<ForeName>Reem Z</ForeName>
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</AffiliationInfo>
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<LastName>Martinez</LastName>
<ForeName>Guadalupe</ForeName>
<Initials>G</Initials>
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<Affiliation>Gastroenterology, Juarez Hospital, Mexico City, Mexico.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Desai</LastName>
<ForeName>Amit P</ForeName>
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</AffiliationInfo>
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<LastName>Kumta</LastName>
<ForeName>Nikhil A</ForeName>
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