AustralieFrV1, PubMed, Checkpoint, bibRecord, 001239

Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis.

Identifieur interne : 001239 ( PubMed/Checkpoint ); précédent : 001238; suivant : 001240

Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis.

Auteurs : Stuart Mcpherson [Royaume-Uni] ; Tim Hardy [Royaume-Uni] ; Jean-Francois Dufour [Suisse] ; Salvatore Petta [Italie] ; Manuel Romero-Gomez [Espagne] ; Mike Allison [Royaume-Uni] ; Claudia P. Oliveira [Brésil] ; Sven Francque [Belgique] ; Luc Van Gaal [Belgique] ; Jörn M. Schattenberg [Allemagne] ; Dina Tiniakos [Royaume-Uni] ; Alastair Burt [Australie] ; Elisabetta Bugianesi [Italie] ; Vlad Ratziu [France] ; Christopher P. Day [Royaume-Uni] ; Quentin M. Anstee [Royaume-Uni]

Source :

The American journal of gastroenterology [ 1572-0241 ] ; 2017.

RBID : pubmed:27725647

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Aire sous la courbe, Alanine transaminase (sang), Aspartate aminotransferases (sang), Biopsie, Cirrhose du foie (anatomopathologie), Cirrhose du foie (diagnostic), Cirrhose du foie (sang), Cirrhose du foie (étiologie), Courbe ROC, Facteurs de l'âge, Faux positifs, Femelle, Foie (anatomopathologie), Humains, Mâle, Numération des plaquettes, Stéatose hépatique non alcoolique (), Sujet âgé, Valeur prédictive des tests, Valeurs de référence.
MESH :
- anatomopathologie : Cirrhose du foie, Foie.
- diagnostic : Cirrhose du foie.
- sang : Alanine transaminase, Aspartate aminotransferases, Cirrhose du foie.
- étiologie : Cirrhose du foie.
- Adulte, Adulte d'âge moyen, Aire sous la courbe, Biopsie, Courbe ROC, Facteurs de l'âge, Faux positifs, Femelle, Humains, Mâle, Numération des plaquettes, Stéatose hépatique non alcoolique, Sujet âgé, Valeur prédictive des tests, Valeurs de référence.

English descriptors

KwdEn :
- Adult, Age Factors, Aged, Alanine Transaminase (blood), Area Under Curve, Aspartate Aminotransferases (blood), Biopsy, False Positive Reactions, Female, Humans, Liver (pathology), Liver Cirrhosis (blood), Liver Cirrhosis (diagnosis), Liver Cirrhosis (etiology), Liver Cirrhosis (pathology), Male, Middle Aged, Non-alcoholic Fatty Liver Disease (complications), Platelet Count, Predictive Value of Tests, ROC Curve, Reference Values.
MESH :
- chemical , blood : Alanine Transaminase, Aspartate Aminotransferases.
- blood : Liver Cirrhosis.
- complications : Non-alcoholic Fatty Liver Disease.
- diagnosis : Liver Cirrhosis.
- etiology : Liver Cirrhosis.
- pathology : Liver, Liver Cirrhosis.
- Adult, Age Factors, Aged, Area Under Curve, Biopsy, False Positive Reactions, Female, Humans, Male, Middle Aged, Platelet Count, Predictive Value of Tests, ROC Curve, Reference Values.

Abstract

Non-invasive fibrosis scores are widely used to identify/exclude advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). However, these scores were principally developed and validated in patients aged between 35 and 65 years of age. The objective of this study was to assess the effect of age on the performance of non-invasive fibrosis tests in NAFLD.

DOI: 10.1038/ajg.2016.453
PubMed: 27725647

Affiliations:

Allemagne, Australie, Belgique, Brésil, Espagne, France, Italie, Royaume-Uni, Suisse
Canton de Berne, Piémont, Rhénanie-Palatinat, État de São Paulo, Île-de-France
Berne, Mayence, Paris, São Paulo, Turin

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 000D38
to stream PubMed, to step Curation: 000D35

Links to Exploration step

pubmed:27725647

Le document en format XML

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<author><name sortKey="Anstee, Quentin M" sort="Anstee, Quentin M" uniqKey="Anstee Q" first="Quentin M" last="Anstee">Quentin M. Anstee</name>
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<author><name sortKey="Van Gaal, Luc" sort="Van Gaal, Luc" uniqKey="Van Gaal L" first="Luc" last="Van Gaal">Luc Van Gaal</name>
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<author><name sortKey="Schattenberg, Jorn M" sort="Schattenberg, Jorn M" uniqKey="Schattenberg J" first="Jörn M" last="Schattenberg">Jörn M. Schattenberg</name>
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<author><name sortKey="Day, Christopher P" sort="Day, Christopher P" uniqKey="Day C" first="Christopher P" last="Day">Christopher P. Day</name>
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<author><name sortKey="Anstee, Quentin M" sort="Anstee, Quentin M" uniqKey="Anstee Q" first="Quentin M" last="Anstee">Quentin M. Anstee</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Age Factors</term>
<term>Aged</term>
<term>Alanine Transaminase (blood)</term>
<term>Area Under Curve</term>
<term>Aspartate Aminotransferases (blood)</term>
<term>Biopsy</term>
<term>False Positive Reactions</term>
<term>Female</term>
<term>Humans</term>
<term>Liver (pathology)</term>
<term>Liver Cirrhosis (blood)</term>
<term>Liver Cirrhosis (diagnosis)</term>
<term>Liver Cirrhosis (etiology)</term>
<term>Liver Cirrhosis (pathology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Non-alcoholic Fatty Liver Disease (complications)</term>
<term>Platelet Count</term>
<term>Predictive Value of Tests</term>
<term>ROC Curve</term>
<term>Reference Values</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aire sous la courbe</term>
<term>Alanine transaminase (sang)</term>
<term>Aspartate aminotransferases (sang)</term>
<term>Biopsie</term>
<term>Cirrhose du foie (anatomopathologie)</term>
<term>Cirrhose du foie (diagnostic)</term>
<term>Cirrhose du foie (sang)</term>
<term>Cirrhose du foie (étiologie)</term>
<term>Courbe ROC</term>
<term>Facteurs de l'âge</term>
<term>Faux positifs</term>
<term>Femelle</term>
<term>Foie (anatomopathologie)</term>
<term>Humains</term>
<term>Mâle</term>
<term>Numération des plaquettes</term>
<term>Stéatose hépatique non alcoolique ()</term>
<term>Sujet âgé</term>
<term>Valeur prédictive des tests</term>
<term>Valeurs de référence</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Alanine Transaminase</term>
<term>Aspartate Aminotransferases</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Cirrhose du foie</term>
<term>Foie</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Liver Cirrhosis</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Non-alcoholic Fatty Liver Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Liver Cirrhosis</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Cirrhose du foie</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Liver Cirrhosis</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Liver</term>
<term>Liver Cirrhosis</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Alanine transaminase</term>
<term>Aspartate aminotransferases</term>
<term>Cirrhose du foie</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Cirrhose du foie</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Age Factors</term>
<term>Aged</term>
<term>Area Under Curve</term>
<term>Biopsy</term>
<term>False Positive Reactions</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Platelet Count</term>
<term>Predictive Value of Tests</term>
<term>ROC Curve</term>
<term>Reference Values</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aire sous la courbe</term>
<term>Biopsie</term>
<term>Courbe ROC</term>
<term>Facteurs de l'âge</term>
<term>Faux positifs</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Numération des plaquettes</term>
<term>Stéatose hépatique non alcoolique</term>
<term>Sujet âgé</term>
<term>Valeur prédictive des tests</term>
<term>Valeurs de référence</term>
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<front><div type="abstract" xml:lang="en">Non-invasive fibrosis scores are widely used to identify/exclude advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). However, these scores were principally developed and validated in patients aged between 35 and 65 years of age. The objective of this study was to assess the effect of age on the performance of non-invasive fibrosis tests in NAFLD.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27725647</PMID>
<DateCreated><Year>2016</Year>
<Month>10</Month>
<Day>11</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>08</Month>
<Day>07</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>09</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1572-0241</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>112</Volume>
<Issue>5</Issue>
<PubDate><Year>2017</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>The American journal of gastroenterology</Title>
<ISOAbbreviation>Am. J. Gastroenterol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis.</ArticleTitle>
<Pagination><MedlinePgn>740-751</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/ajg.2016.453</ELocationID>
<Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">Non-invasive fibrosis scores are widely used to identify/exclude advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). However, these scores were principally developed and validated in patients aged between 35 and 65 years of age. The objective of this study was to assess the effect of age on the performance of non-invasive fibrosis tests in NAFLD.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Patients were recruited from European specialist hepatology clinics. The cohort was divided into five age-based groups: ≤35 (n=74), 36-45 (n=96), 46-55 (n=197), 56-64 (n=191), and ≥65 years (n=76), and the performance of the aspartate aminotransferase (AST)/alanine transaminase (ALT) ratio, fibrosis 4 (FIB-4), and NAFLD fibrosis score (NFS) for advanced fibrosis (stage F3-F4) for each group was assessed using liver biopsy as the standard.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Six hundred and thirty-four patients were included. The diagnostic accuracy of the AST/ALT ratio was lower than NFS and FIB-4 in all the age groups. The AST/ALT ratio, NFS, and FIB-4 score performed poorly for a diagnosis of advanced fibrosis in those aged ≤35 years (area under the receiver operating characteristic curves (AUROCs 0.52, 0.52, and 0.60, respectively). For all groups >35 years, AUROCs for advanced fibrosis were similar for the NFS and FIB-4 score (range 0.77-0.84). However, the specificity for advanced fibrosis using the FIB-4 and NFS declined with age, becoming unacceptably low in those aged ≥65 years (35% for FIB-4 and 20% for NFS). New cutoffs were derived (and validated) for those aged ≥65 years, which improved specificity to 70% without adversely affecting sensitivity (FIB-4 2.0, sensitivity 77%; NFS 0.12, sensitivity 80%).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The NFS and FIB-4 scores have similar accuracy for advanced fibrosis in patients aged >35 years. However, the specificity for advanced fibrosis is unacceptably low in patients aged ≥65 years, resulting in a high false positive rate. New thresholds for use in patients aged ≥65 years are proposed to address this issue.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>McPherson</LastName>
<ForeName>Stuart</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Liver Unit, Newcastle Upon Tyne Hospitals NHS Trust, Freeman Hospital, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hardy</LastName>
<ForeName>Tim</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Liver Unit, Newcastle Upon Tyne Hospitals NHS Trust, Freeman Hospital, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dufour</LastName>
<ForeName>Jean-Francois</ForeName>
<Initials>JF</Initials>
<AffiliationInfo><Affiliation>University Clinic for Visceral Surgery and Medicine, University of Berne, Berne, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Petta</LastName>
<ForeName>Salvatore</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Section of Gastroenterology, Di.Bi.M.I.S., University of Palermo, Palermo, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Romero-Gomez</LastName>
<ForeName>Manuel</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>UCM Digestive Diseases, Hospital Universitario Virgen Macarena-Virgen del Rocío, Sevilla, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Allison</LastName>
<ForeName>Mike</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Liver Unit, Addenbrooke's Hospital, Cambridge Biomedical Research Centre, Cambridge, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Oliveira</LastName>
<ForeName>Claudia P</ForeName>
<Initials>CP</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Francque</LastName>
<ForeName>Sven</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Gastroenterology Hepatology, Antwerp University Hospital, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Van Gaal</LastName>
<ForeName>Luc</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schattenberg</LastName>
<ForeName>Jörn M</ForeName>
<Initials>JM</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, University Hospital, Mainz, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tiniakos</LastName>
<ForeName>Dina</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Liver Unit, Newcastle Upon Tyne Hospitals NHS Trust, Freeman Hospital, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Burt</LastName>
<ForeName>Alastair</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>School of Medicine, University of Adelaide, Adelaide, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bugianesi</LastName>
<ForeName>Elisabetta</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Department of Medical Sciences, Division of Gastro-Hepatology, A.O. Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ratziu</LastName>
<ForeName>Vlad</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Institute of Cardiometabolism and Nutrition, Pitié-Salpêtrière Hospital, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Day</LastName>
<ForeName>Christopher P</ForeName>
<Initials>CP</Initials>
<AffiliationInfo><Affiliation>Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Liver Unit, Newcastle Upon Tyne Hospitals NHS Trust, Freeman Hospital, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Anstee</LastName>
<ForeName>Quentin M</ForeName>
<Initials>QM</Initials>
<AffiliationInfo><Affiliation>Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Liver Unit, Newcastle Upon Tyne Hospitals NHS Trust, Freeman Hospital, Newcastle upon Tyne, UK.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2016</Year>
<Month>10</Month>
<Day>11</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Am J Gastroenterol</MedlineTA>
<NlmUniqueID>0421030</NlmUniqueID>
<ISSNLinking>0002-9270</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>EC 2.6.1.1</RegistryNumber>
<NameOfSubstance UI="D001219">Aspartate Aminotransferases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.6.1.2</RegistryNumber>
<NameOfSubstance UI="D000410">Alanine Transaminase</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000367" MajorTopicYN="Y">Age Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000410" MajorTopicYN="N">Alanine Transaminase</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019540" MajorTopicYN="N">Area Under Curve</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001219" MajorTopicYN="N">Aspartate Aminotransferases</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001706" MajorTopicYN="N">Biopsy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005189" MajorTopicYN="N">False Positive Reactions</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008099" MajorTopicYN="N">Liver</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008103" MajorTopicYN="N">Liver Cirrhosis</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D065626" MajorTopicYN="N">Non-alcoholic Fatty Liver Disease</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010976" MajorTopicYN="N">Platelet Count</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012372" MajorTopicYN="N">ROC Curve</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012016" MajorTopicYN="N">Reference Values</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>04</Month>
<Day>06</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>07</Month>
<Day>03</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2016</Year>
<Month>10</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>8</Month>
<Day>8</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2016</Year>
<Month>10</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">27725647</ArticleId>
<ArticleId IdType="pii">ajg2016453</ArticleId>
<ArticleId IdType="doi">10.1038/ajg.2016.453</ArticleId>
<ArticleId IdType="pmc">PMC5418560</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Belgique</li>
<li>Brésil</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Royaume-Uni</li>
<li>Suisse</li>
</country>
<region><li>Canton de Berne</li>
<li>Piémont</li>
<li>Rhénanie-Palatinat</li>
<li>État de São Paulo</li>
<li>Île-de-France</li>
</region>
<settlement><li>Berne</li>
<li>Mayence</li>
<li>Paris</li>
<li>São Paulo</li>
<li>Turin</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><noRegion><name sortKey="Mcpherson, Stuart" sort="Mcpherson, Stuart" uniqKey="Mcpherson S" first="Stuart" last="Mcpherson">Stuart Mcpherson</name>
</noRegion>
<name sortKey="Allison, Mike" sort="Allison, Mike" uniqKey="Allison M" first="Mike" last="Allison">Mike Allison</name>
<name sortKey="Anstee, Quentin M" sort="Anstee, Quentin M" uniqKey="Anstee Q" first="Quentin M" last="Anstee">Quentin M. Anstee</name>
<name sortKey="Day, Christopher P" sort="Day, Christopher P" uniqKey="Day C" first="Christopher P" last="Day">Christopher P. Day</name>
<name sortKey="Hardy, Tim" sort="Hardy, Tim" uniqKey="Hardy T" first="Tim" last="Hardy">Tim Hardy</name>
<name sortKey="Tiniakos, Dina" sort="Tiniakos, Dina" uniqKey="Tiniakos D" first="Dina" last="Tiniakos">Dina Tiniakos</name>
</country>
<country name="Suisse"><region name="Canton de Berne"><name sortKey="Dufour, Jean Francois" sort="Dufour, Jean Francois" uniqKey="Dufour J" first="Jean-Francois" last="Dufour">Jean-Francois Dufour</name>
</region>
</country>
<country name="Italie"><noRegion><name sortKey="Petta, Salvatore" sort="Petta, Salvatore" uniqKey="Petta S" first="Salvatore" last="Petta">Salvatore Petta</name>
</noRegion>
<name sortKey="Bugianesi, Elisabetta" sort="Bugianesi, Elisabetta" uniqKey="Bugianesi E" first="Elisabetta" last="Bugianesi">Elisabetta Bugianesi</name>
</country>
<country name="Espagne"><noRegion><name sortKey="Romero Gomez, Manuel" sort="Romero Gomez, Manuel" uniqKey="Romero Gomez M" first="Manuel" last="Romero-Gomez">Manuel Romero-Gomez</name>
</noRegion>
</country>
<country name="Brésil"><region name="État de São Paulo"><name sortKey="Oliveira, Claudia P" sort="Oliveira, Claudia P" uniqKey="Oliveira C" first="Claudia P" last="Oliveira">Claudia P. Oliveira</name>
</region>
</country>
<country name="Belgique"><noRegion><name sortKey="Francque, Sven" sort="Francque, Sven" uniqKey="Francque S" first="Sven" last="Francque">Sven Francque</name>
</noRegion>
<name sortKey="Van Gaal, Luc" sort="Van Gaal, Luc" uniqKey="Van Gaal L" first="Luc" last="Van Gaal">Luc Van Gaal</name>
</country>
<country name="Allemagne"><region name="Rhénanie-Palatinat"><name sortKey="Schattenberg, Jorn M" sort="Schattenberg, Jorn M" uniqKey="Schattenberg J" first="Jörn M" last="Schattenberg">Jörn M. Schattenberg</name>
</region>
</country>
<country name="Australie"><noRegion><name sortKey="Burt, Alastair" sort="Burt, Alastair" uniqKey="Burt A" first="Alastair" last="Burt">Alastair Burt</name>
</noRegion>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Ratziu, Vlad" sort="Ratziu, Vlad" uniqKey="Ratziu V" first="Vlad" last="Ratziu">Vlad Ratziu</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001239 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 001239 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:27725647
   |texte=   Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:27725647" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les relations entre la France et l'Australie

Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis.

Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis.

Source :

Descripteurs français

English descriptors

Abstract

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