All-cause mortality in HIV-positive adults starting combination antiretroviral therapy: correcting for loss to follow-up.
Identifieur interne : 001232 ( PubMed/Checkpoint ); précédent : 001231; suivant : 001233All-cause mortality in HIV-positive adults starting combination antiretroviral therapy: correcting for loss to follow-up.
Auteurs : Nanina Anderegg [États-Unis] ; Leigh F. Johnson ; Elizabeth Zaniewski ; Keri N. Althoff ; Eric Balestre ; Matthew Law ; Denis Nash ; Bryan E. Shepherd ; Constantin T. Yiannoutsos ; Matthias EggerSource :
- AIDS (London, England) [ 1473-5571 ] ; 2017.
Abstract
To estimate mortality in HIV-positive patients starting combination antiretroviral therapy (ART) and to discuss different approaches to calculating correction factors to account for loss to follow-up.
DOI: 10.1097/QAD.0000000000001321
PubMed: 28296798
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">All-cause mortality in HIV-positive adults starting combination antiretroviral therapy: correcting for loss to follow-up.</title><author><name sortKey="Anderegg, Nanina" sort="Anderegg, Nanina" uniqKey="Anderegg N" first="Nanina" last="Anderegg">Nanina Anderegg</name><affiliation wicri:level="4"><nlm:affiliation>aInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland bCentre for Infectious Disease Epidemiology and Research (CIDER), University of Cape Town, Cape Town, South Africa cJohn Hopkins University, Baltimore, Maryland, USA dISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Université Bordeaux, Bordeaux Cedex, France eKirby Institute, UNSW, Sydney, New South Wales, Australia fInstitute for Implementation Science in Population Health, City University of New York, New York, USA gDepartment of Epidemiology and Biostatistics, City University of New York School of Public Health, New York, New York, USA hDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA iDepartment of Biostatistics, Indiana University School of Public Health, Indianapolis, Indiana, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>aInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland bCentre for Infectious Disease Epidemiology and Research (CIDER), University of Cape Town, Cape Town, South Africa cJohn Hopkins University, Baltimore, Maryland, USA dISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Université Bordeaux, Bordeaux Cedex, France eKirby Institute, UNSW, Sydney, New South Wales, Australia fInstitute for Implementation Science in Population Health, City University of New York, New York, USA gDepartment of Epidemiology and Biostatistics, City University of New York School of Public Health, New York, New York, USA hDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA iDepartment of Biostatistics, Indiana University School of Public Health, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region><settlement type="city">Berne</settlement></placeName><orgName type="university">Université de Berne</orgName></affiliation></author><author><name sortKey="Johnson, Leigh F" sort="Johnson, Leigh F" uniqKey="Johnson L" first="Leigh F" last="Johnson">Leigh F. Johnson</name></author><author><name sortKey="Zaniewski, Elizabeth" sort="Zaniewski, Elizabeth" uniqKey="Zaniewski E" first="Elizabeth" last="Zaniewski">Elizabeth Zaniewski</name></author><author><name sortKey="Althoff, Keri N" sort="Althoff, Keri N" uniqKey="Althoff K" first="Keri N" last="Althoff">Keri N. Althoff</name></author><author><name sortKey="Balestre, Eric" sort="Balestre, Eric" uniqKey="Balestre E" first="Eric" last="Balestre">Eric Balestre</name></author><author><name sortKey="Law, Matthew" sort="Law, Matthew" uniqKey="Law M" first="Matthew" last="Law">Matthew Law</name></author><author><name sortKey="Nash, Denis" sort="Nash, Denis" uniqKey="Nash D" first="Denis" last="Nash">Denis Nash</name></author><author><name sortKey="Shepherd, Bryan E" sort="Shepherd, Bryan E" uniqKey="Shepherd B" first="Bryan E" last="Shepherd">Bryan E. Shepherd</name></author><author><name sortKey="Yiannoutsos, Constantin T" sort="Yiannoutsos, Constantin T" uniqKey="Yiannoutsos C" first="Constantin T" last="Yiannoutsos">Constantin T. Yiannoutsos</name></author><author><name sortKey="Egger, Matthias" sort="Egger, Matthias" uniqKey="Egger M" first="Matthias" last="Egger">Matthias Egger</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28296798</idno><idno type="pmid">28296798</idno><idno type="doi">10.1097/QAD.0000000000001321</idno><idno type="wicri:Area/PubMed/Corpus">000E55</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E55</idno><idno type="wicri:Area/PubMed/Curation">000E52</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E52</idno><idno type="wicri:Area/PubMed/Checkpoint">000E52</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000E52</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">All-cause mortality in HIV-positive adults starting combination antiretroviral therapy: correcting for loss to follow-up.</title><author><name sortKey="Anderegg, Nanina" sort="Anderegg, Nanina" uniqKey="Anderegg N" first="Nanina" last="Anderegg">Nanina Anderegg</name><affiliation wicri:level="4"><nlm:affiliation>aInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland bCentre for Infectious Disease Epidemiology and Research (CIDER), University of Cape Town, Cape Town, South Africa cJohn Hopkins University, Baltimore, Maryland, USA dISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Université Bordeaux, Bordeaux Cedex, France eKirby Institute, UNSW, Sydney, New South Wales, Australia fInstitute for Implementation Science in Population Health, City University of New York, New York, USA gDepartment of Epidemiology and Biostatistics, City University of New York School of Public Health, New York, New York, USA hDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA iDepartment of Biostatistics, Indiana University School of Public Health, Indianapolis, Indiana, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>aInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland bCentre for Infectious Disease Epidemiology and Research (CIDER), University of Cape Town, Cape Town, South Africa cJohn Hopkins University, Baltimore, Maryland, USA dISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Université Bordeaux, Bordeaux Cedex, France eKirby Institute, UNSW, Sydney, New South Wales, Australia fInstitute for Implementation Science in Population Health, City University of New York, New York, USA gDepartment of Epidemiology and Biostatistics, City University of New York School of Public Health, New York, New York, USA hDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA iDepartment of Biostatistics, Indiana University School of Public Health, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region><settlement type="city">Berne</settlement></placeName><orgName type="university">Université de Berne</orgName></affiliation></author><author><name sortKey="Johnson, Leigh F" sort="Johnson, Leigh F" uniqKey="Johnson L" first="Leigh F" last="Johnson">Leigh F. Johnson</name></author><author><name sortKey="Zaniewski, Elizabeth" sort="Zaniewski, Elizabeth" uniqKey="Zaniewski E" first="Elizabeth" last="Zaniewski">Elizabeth Zaniewski</name></author><author><name sortKey="Althoff, Keri N" sort="Althoff, Keri N" uniqKey="Althoff K" first="Keri N" last="Althoff">Keri N. Althoff</name></author><author><name sortKey="Balestre, Eric" sort="Balestre, Eric" uniqKey="Balestre E" first="Eric" last="Balestre">Eric Balestre</name></author><author><name sortKey="Law, Matthew" sort="Law, Matthew" uniqKey="Law M" first="Matthew" last="Law">Matthew Law</name></author><author><name sortKey="Nash, Denis" sort="Nash, Denis" uniqKey="Nash D" first="Denis" last="Nash">Denis Nash</name></author><author><name sortKey="Shepherd, Bryan E" sort="Shepherd, Bryan E" uniqKey="Shepherd B" first="Bryan E" last="Shepherd">Bryan E. Shepherd</name></author><author><name sortKey="Yiannoutsos, Constantin T" sort="Yiannoutsos, Constantin T" uniqKey="Yiannoutsos C" first="Constantin T" last="Yiannoutsos">Constantin T. Yiannoutsos</name></author><author><name sortKey="Egger, Matthias" sort="Egger, Matthias" uniqKey="Egger M" first="Matthias" last="Egger">Matthias Egger</name></author></analytic><series><title level="j">AIDS (London, England)</title><idno type="eISSN">1473-5571</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To estimate mortality in HIV-positive patients starting combination antiretroviral therapy (ART) and to discuss different approaches to calculating correction factors to account for loss to follow-up.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28296798</PMID><DateCreated><Year>2017</Year><Month>03</Month><Day>15</Day></DateCreated><DateRevised><Year>2017</Year><Month>08</Month><Day>04</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1473-5571</ISSN><JournalIssue CitedMedium="Internet"><Volume>31 Suppl 1</Volume><PubDate><Year>2017</Year><Month>Apr</Month></PubDate></JournalIssue><Title>AIDS (London, England)</Title><ISOAbbreviation>AIDS</ISOAbbreviation></Journal><ArticleTitle>All-cause mortality in HIV-positive adults starting combination antiretroviral therapy: correcting for loss to follow-up.</ArticleTitle><Pagination><MedlinePgn>S31-S40</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/QAD.0000000000001321</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To estimate mortality in HIV-positive patients starting combination antiretroviral therapy (ART) and to discuss different approaches to calculating correction factors to account for loss to follow-up.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A total of 222 096 adult HIV-positive patients who started ART 2009-2014 in clinics participating in the International epidemiology Databases to Evaluate AIDS collaboration in 43 countries in sub-Saharan Africa, Asia Pacific, Latin America, and North America were included. To allow for underascertainment of deaths due to loss to follow-up, two correction factors (one for the period 0-6 months on ART and one for later periods) or 168 correction factors (combinations of two sexes, three time periods after ART initiation, four age groups, and seven CD4 groups) based on tracing patients lost in Kenya and data linkages in South Africa were applied. Corrected mortality rates were compared with a worst case scenario assuming all patients lost to follow-up had died.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Loss to follow-up differed between regions; rates were lowest in central Africa and highest in east Africa. Compared with using two correction factors (1.64 for the initial ART period and 2.19 for later), applying 168 correction factors (range 1.03-4.75) more often resulted in implausible mortality rates that exceeded the worst case scenario. Corrected mortality rates varied widely, ranging from 0.2 per 100 person-years to 54 per 100 person-years depending on region and covariates.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Implausible rates were less common with the simpler approach based on two correction factors. The corrected mortality rates will be useful to international agencies, national programmes, and modellers.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Anderegg</LastName><ForeName>Nanina</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>aInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland bCentre for Infectious Disease Epidemiology and Research (CIDER), University of Cape Town, Cape Town, South Africa cJohn Hopkins University, Baltimore, Maryland, USA dISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Université Bordeaux, Bordeaux Cedex, France eKirby Institute, UNSW, Sydney, New South Wales, Australia fInstitute for Implementation Science in Population Health, City University of New York, New York, USA gDepartment of Epidemiology and Biostatistics, City University of New York School of Public Health, New York, New York, USA hDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA iDepartment of Biostatistics, Indiana University School of Public Health, Indianapolis, Indiana, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johnson</LastName><ForeName>Leigh F</ForeName><Initials>LF</Initials></Author><Author ValidYN="Y"><LastName>Zaniewski</LastName><ForeName>Elizabeth</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Althoff</LastName><ForeName>Keri N</ForeName><Initials>KN</Initials></Author><Author ValidYN="Y"><LastName>Balestre</LastName><ForeName>Eric</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Law</LastName><ForeName>Matthew</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Nash</LastName><ForeName>Denis</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Shepherd</LastName><ForeName>Bryan E</ForeName><Initials>BE</Initials></Author><Author ValidYN="Y"><LastName>Yiannoutsos</LastName><ForeName>Constantin T</ForeName><Initials>CT</Initials></Author><Author ValidYN="Y"><LastName>Egger</LastName><ForeName>Matthias</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><CollectiveName>IeDEA, MeSH consortia</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01 AA016893</GrantID><Acronym>AA</Acronym><Agency>NIAAA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P30 AI027767</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 AI035042</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 AI069434</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>M01 RR000079</GrantID><Acronym>RR</Acronym><Agency>NCRR NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>K23 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HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 AI069907</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 AI035043</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P30 AI027757</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>UL1 RR025747</GrantID><Acronym>RR</Acronym><Agency>NCRR NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 DA012568</GrantID><Acronym>DA</Acronym><Agency>NIDA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 AI035040</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 AI034993</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>M01 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States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>AIDS</MedlineTA><NlmUniqueID>8710219</NlmUniqueID><ISSNLinking>0269-9370</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>PLoS Med. 2011 Jan 18;8(1):e1000390</RefSource><PMID Version="1">21267057</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sex Transm Infect. 2006 Jun;82 Suppl 3:iii45-50</RefSource><PMID Version="1">16735293</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Int J Epidemiol. 2007 Oct;36(5):969-76</RefSource><PMID Version="1">17846055</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Acquir Immune Defic Syndr. 2015 May 1;69(1):98-108</RefSource><PMID Version="1">25942461</PMID></CommentsCorrections><CommentsCorrections 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Version="1">28102610</PMID></CommentsCorrections></CommentsCorrectionsList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pmc-release"><Year>2018</Year><Month>04</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>3</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>3</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>3</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28296798</ArticleId><ArticleId IdType="doi">10.1097/QAD.0000000000001321</ArticleId><ArticleId IdType="pii">00002030-201704001-00005</ArticleId><ArticleId IdType="pmc">PMC5540664</ArticleId><ArticleId IdType="mid">NIHMS831641</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Indiana</li></region><settlement><li>Berne</li></settlement><orgName><li>Université de Berne</li></orgName></list><tree><noCountry><name sortKey="Althoff, Keri N" sort="Althoff, Keri N" uniqKey="Althoff K" first="Keri N" last="Althoff">Keri N. Althoff</name><name sortKey="Balestre, Eric" sort="Balestre, Eric" uniqKey="Balestre E" first="Eric" last="Balestre">Eric Balestre</name><name sortKey="Egger, Matthias" sort="Egger, Matthias" uniqKey="Egger M" first="Matthias" last="Egger">Matthias Egger</name><name sortKey="Johnson, Leigh F" sort="Johnson, Leigh F" uniqKey="Johnson L" first="Leigh F" last="Johnson">Leigh F. Johnson</name><name sortKey="Law, Matthew" sort="Law, Matthew" uniqKey="Law M" first="Matthew" last="Law">Matthew Law</name><name sortKey="Nash, Denis" sort="Nash, Denis" uniqKey="Nash D" first="Denis" last="Nash">Denis Nash</name><name sortKey="Shepherd, Bryan E" sort="Shepherd, Bryan E" uniqKey="Shepherd B" first="Bryan E" last="Shepherd">Bryan E. Shepherd</name><name sortKey="Yiannoutsos, Constantin T" sort="Yiannoutsos, Constantin T" uniqKey="Yiannoutsos C" first="Constantin T" last="Yiannoutsos">Constantin T. Yiannoutsos</name><name sortKey="Zaniewski, Elizabeth" sort="Zaniewski, Elizabeth" uniqKey="Zaniewski E" first="Elizabeth" last="Zaniewski">Elizabeth Zaniewski</name></noCountry><country name="États-Unis"><region name="Indiana"><name sortKey="Anderegg, Nanina" sort="Anderegg, Nanina" uniqKey="Anderegg N" first="Nanina" last="Anderegg">Nanina Anderegg</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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