Asthma Medication Ratio Phenotypes in Elderly Women.
Identifieur interne : 001149 ( PubMed/Checkpoint ); précédent : 001148; suivant : 001150Asthma Medication Ratio Phenotypes in Elderly Women.
Auteurs : Sébastien Chanoine [France] ; Isabelle Pin [France] ; Margaux Sanchez [France] ; Sofia Temam [France] ; Christophe Pison [France] ; Nicole Le Moual [France] ; Gianluca Severi [Australie] ; Marie-Christine Boutron-Ruault [France] ; Agnès Fournier [France] ; Jean Bousquet [France] ; Pierrick Bedouch [France] ; Raphaëlle Varraso [France] ; Valérie Siroux [France]Source :
- The journal of allergy and clinical immunology. In practice [ 2213-2201 ] ; 2017.
Abstract
With population aging, further asthma research is needed in the elderly.
DOI: 10.1016/j.jaip.2017.07.014
PubMed: 28958739
Affiliations:
- Australie, France
- Auvergne-Rhône-Alpes, Languedoc-Roussillon, Occitanie (région administrative), Rhône-Alpes, Victoria (État)
- Grenoble, Melbourne, Montpellier
- Université Grenoble-Alpes, Université de Melbourne
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Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Faculté de Médecine, Université Paris Sud, Kremlin Bicêtre</wicri:regionArea><wicri:noRegion>Kremlin Bicêtre</wicri:noRegion><wicri:noRegion>Kremlin Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Pison, Christophe" sort="Pison, Christophe" uniqKey="Pison C" first="Christophe" last="Pison">Christophe Pison</name><affiliation wicri:level="4"><nlm:affiliation>Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Pôle Thorax et Vaisseaux, Centre Hospitalier Universitaire Grenoble Alpes, Clinique Universitaire de Pneumologie, Grenoble, France; Laboratoire de Bioénergétique Fondamentale et Appliquée, Institut National de la Santé et de la Recherche Médicale U1055, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Pôle Thorax et Vaisseaux, Centre Hospitalier Universitaire Grenoble Alpes, Clinique Universitaire de Pneumologie, Grenoble, France; Laboratoire de Bioénergétique Fondamentale et Appliquée, Institut National de la Santé et de la Recherche Médicale U1055, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement><settlement type="city">Grenoble</settlement></placeName><orgName type="university">Université Grenoble-Alpes</orgName></affiliation></author><author><name sortKey="Le Moual, Nicole" sort="Le Moual, Nicole" uniqKey="Le Moual N" first="Nicole" last="Le Moual">Nicole Le Moual</name><affiliation wicri:level="1"><nlm:affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux</wicri:regionArea><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="4"><nlm:affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France; Team of Molecular and Genetic Epidemiology, Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and The University of Melbourne, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France; Team of Molecular and Genetic Epidemiology, Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Boutron Ruault, Marie Christine" sort="Boutron Ruault, Marie Christine" uniqKey="Boutron Ruault M" first="Marie-Christine" last="Boutron-Ruault">Marie-Christine Boutron-Ruault</name><affiliation wicri:level="1"><nlm:affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France. Electronic address: marie-christine.boutron@gustaveroussy.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Fournier, Agnes" sort="Fournier, Agnes" uniqKey="Fournier A" first="Agnès" last="Fournier">Agnès Fournier</name><affiliation wicri:level="1"><nlm:affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Bousquet, Jean" sort="Bousquet, Jean" uniqKey="Bousquet J" first="Jean" last="Bousquet">Jean Bousquet</name><affiliation wicri:level="3"><nlm:affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Clinique de Pneumologie, Centre Hospitalier Universitaire de Montpellier, Montpellier, France; MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Clinique de Pneumologie, Centre Hospitalier Universitaire de Montpellier, Montpellier, France; MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Bedouch, Pierrick" sort="Bedouch, Pierrick" uniqKey="Bedouch P" first="Pierrick" last="Bedouch">Pierrick Bedouch</name><affiliation wicri:level="3"><nlm:affiliation>Pôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France; Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Equipe Techniques pour l'Evaluation et la Modélisation des Actions de Santé (ThEMAS), Centre National de la Recherche Scientifique, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications (TIMC-IMAG), Unité Mixte de Recherche 5525, Université Grenoble Alpes, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France; Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Equipe Techniques pour l'Evaluation et la Modélisation des Actions de Santé (ThEMAS), Centre National de la Recherche Scientifique, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications (TIMC-IMAG), Unité Mixte de Recherche 5525, Université Grenoble Alpes, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Varraso, Raphaelle" sort="Varraso, Raphaelle" uniqKey="Varraso R" first="Raphaëlle" last="Varraso">Raphaëlle Varraso</name><affiliation wicri:level="1"><nlm:affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux</wicri:regionArea><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion></affiliation></author><author><name sortKey="Siroux, Valerie" sort="Siroux, Valerie" uniqKey="Siroux V" first="Valérie" last="Siroux">Valérie Siroux</name><affiliation wicri:level="4"><nlm:affiliation>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement><settlement type="city">Grenoble</settlement></placeName><orgName type="university">Université Grenoble-Alpes</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28958739</idno><idno type="pmid">28958739</idno><idno type="doi">10.1016/j.jaip.2017.07.014</idno><idno type="wicri:Area/PubMed/Corpus">000574</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000574</idno><idno type="wicri:Area/PubMed/Curation">000572</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000572</idno><idno type="wicri:Area/PubMed/Checkpoint">000572</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000572</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Asthma Medication Ratio Phenotypes in Elderly Women.</title><author><name sortKey="Chanoine, Sebastien" sort="Chanoine, Sebastien" uniqKey="Chanoine S" first="Sébastien" last="Chanoine">Sébastien Chanoine</name><affiliation wicri:level="4"><nlm:affiliation>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France; Pôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France; Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France; Pôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France; Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement><settlement type="city">Grenoble</settlement></placeName><orgName type="university">Université Grenoble-Alpes</orgName></affiliation></author><author><name sortKey="Pin, Isabelle" sort="Pin, Isabelle" uniqKey="Pin I" first="Isabelle" last="Pin">Isabelle Pin</name><affiliation wicri:level="4"><nlm:affiliation>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France; Clinique de Pédiatrie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France; Clinique de Pédiatrie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement><settlement type="city">Grenoble</settlement></placeName><orgName type="university">Université Grenoble-Alpes</orgName></affiliation></author><author><name sortKey="Sanchez, Margaux" sort="Sanchez, Margaux" uniqKey="Sanchez M" first="Margaux" last="Sanchez">Margaux Sanchez</name><affiliation wicri:level="1"><nlm:affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux</wicri:regionArea><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion></affiliation></author><author><name sortKey="Temam, Sofia" sort="Temam, Sofia" uniqKey="Temam S" first="Sofia" last="Temam">Sofia Temam</name><affiliation wicri:level="1"><nlm:affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Faculté de Médecine, Université Paris Sud, Kremlin Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Faculté de Médecine, Université Paris Sud, Kremlin Bicêtre</wicri:regionArea><wicri:noRegion>Kremlin Bicêtre</wicri:noRegion><wicri:noRegion>Kremlin Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Pison, Christophe" sort="Pison, Christophe" uniqKey="Pison C" first="Christophe" last="Pison">Christophe Pison</name><affiliation wicri:level="4"><nlm:affiliation>Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Pôle Thorax et Vaisseaux, Centre Hospitalier Universitaire Grenoble Alpes, Clinique Universitaire de Pneumologie, Grenoble, France; Laboratoire de Bioénergétique Fondamentale et Appliquée, Institut National de la Santé et de la Recherche Médicale U1055, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Pôle Thorax et Vaisseaux, Centre Hospitalier Universitaire Grenoble Alpes, Clinique Universitaire de Pneumologie, Grenoble, France; Laboratoire de Bioénergétique Fondamentale et Appliquée, Institut National de la Santé et de la Recherche Médicale U1055, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement><settlement type="city">Grenoble</settlement></placeName><orgName type="university">Université Grenoble-Alpes</orgName></affiliation></author><author><name sortKey="Le Moual, Nicole" sort="Le Moual, Nicole" uniqKey="Le Moual N" first="Nicole" last="Le Moual">Nicole Le Moual</name><affiliation wicri:level="1"><nlm:affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux</wicri:regionArea><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="4"><nlm:affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France; Team of Molecular and Genetic Epidemiology, Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and The University of Melbourne, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France; Team of Molecular and Genetic Epidemiology, Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Boutron Ruault, Marie Christine" sort="Boutron Ruault, Marie Christine" uniqKey="Boutron Ruault M" first="Marie-Christine" last="Boutron-Ruault">Marie-Christine Boutron-Ruault</name><affiliation wicri:level="1"><nlm:affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France. Electronic address: marie-christine.boutron@gustaveroussy.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Fournier, Agnes" sort="Fournier, Agnes" uniqKey="Fournier A" first="Agnès" last="Fournier">Agnès Fournier</name><affiliation wicri:level="1"><nlm:affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Bousquet, Jean" sort="Bousquet, Jean" uniqKey="Bousquet J" first="Jean" last="Bousquet">Jean Bousquet</name><affiliation wicri:level="3"><nlm:affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Clinique de Pneumologie, Centre Hospitalier Universitaire de Montpellier, Montpellier, France; MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Clinique de Pneumologie, Centre Hospitalier Universitaire de Montpellier, Montpellier, France; MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Bedouch, Pierrick" sort="Bedouch, Pierrick" uniqKey="Bedouch P" first="Pierrick" last="Bedouch">Pierrick Bedouch</name><affiliation wicri:level="3"><nlm:affiliation>Pôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France; Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Equipe Techniques pour l'Evaluation et la Modélisation des Actions de Santé (ThEMAS), Centre National de la Recherche Scientifique, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications (TIMC-IMAG), Unité Mixte de Recherche 5525, Université Grenoble Alpes, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France; Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Equipe Techniques pour l'Evaluation et la Modélisation des Actions de Santé (ThEMAS), Centre National de la Recherche Scientifique, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications (TIMC-IMAG), Unité Mixte de Recherche 5525, Université Grenoble Alpes, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Varraso, Raphaelle" sort="Varraso, Raphaelle" uniqKey="Varraso R" first="Raphaëlle" last="Varraso">Raphaëlle Varraso</name><affiliation wicri:level="1"><nlm:affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux</wicri:regionArea><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion><wicri:noRegion>Montigny le Bretonneux</wicri:noRegion></affiliation></author><author><name sortKey="Siroux, Valerie" sort="Siroux, Valerie" uniqKey="Siroux V" first="Valérie" last="Siroux">Valérie Siroux</name><affiliation wicri:level="4"><nlm:affiliation>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement><settlement type="city">Grenoble</settlement></placeName><orgName type="university">Université Grenoble-Alpes</orgName></affiliation></author></analytic><series><title level="j">The journal of allergy and clinical immunology. In practice</title><idno type="eISSN">2213-2201</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">With population aging, further asthma research is needed in the elderly.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">28958739</PMID><DateCreated><Year>2017</Year><Month>09</Month><Day>29</Day></DateCreated><DateRevised><Year>2017</Year><Month>09</Month><Day>29</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2213-2201</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2017</Year><Month>Sep</Month><Day>22</Day></PubDate></JournalIssue><Title>The journal of allergy and clinical immunology. In practice</Title><ISOAbbreviation>J Allergy Clin Immunol Pract</ISOAbbreviation></Journal><ArticleTitle>Asthma Medication Ratio Phenotypes in Elderly Women.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">S2213-2198(17)30539-1</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jaip.2017.07.014</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">With population aging, further asthma research is needed in the elderly.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">We assessed the relevance of the controller-to-total asthma medication ratio and its fluctuations over time to identify participants with a subsequent risk of poor asthma-related outcomes among well-characterized elderly women.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We studied 4,328 women with ever asthma (69.6 ± 6.1 years) from the Asthma-E3N study (Etude Epidémiologique auprès des femmes de la Mutuelle Générale de l'Education Nationale), which combined drug claims data since 2004 with prospective individual characteristics. The levels of the yearly controller-to-total asthma medication ratio from 2004 to 2011 were included in latent class analysis to identify groups of women characterized by specific long-term fluctuations of the ratio. Multiple regression models estimated the subsequent risk of uncontrolled asthma, asthma attacks, asthma exacerbations, and poor asthma-related quality of life associated with the level and the fluctuations of the ratio.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A short-term (12 months) ratio below 0.5 was associated with a higher risk of subsequent uncontrolled asthma, asthma attacks, asthma exacerbations (odds ratio [95% confidence interval (CI)] = 2.13 [1.41; 3.23], 1.51 [1.01; 2.26], and 2.18 [1.37; 3.44], respectively), and a lower total asthma quality of life questionnaire score (β [95% CI] = -0.49 [-0.68; -0.29]). The analysis of the long-term fluctuations of the ratio identified 5 profiles ("Never regular treatment," 53.2%; "Persistent high ratio," 21.8%; "Increasing ratio," 4.4%; "Initiating treatment," 8.8%; "Treatment discontinuation," 11.8%). The subsequent risk of poor asthma-related outcomes was significantly higher in profiles characterized by no or interrupted asthma maintenance therapy over time, compared with the "Persistent high ratio" group.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The level and the long-term fluctuations of the controller-to-total asthma medication ratio predict poor asthma-related outcomes in elderly women.</AbstractText><CopyrightInformation>Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chanoine</LastName><ForeName>Sébastien</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France; Pôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France; Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pin</LastName><ForeName>Isabelle</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France; Clinique de Pédiatrie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanchez</LastName><ForeName>Margaux</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Temam</LastName><ForeName>Sofia</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Faculté de Médecine, Université Paris Sud, Kremlin Bicêtre, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pison</LastName><ForeName>Christophe</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Pôle Thorax et Vaisseaux, Centre Hospitalier Universitaire Grenoble Alpes, Clinique Universitaire de Pneumologie, Grenoble, France; Laboratoire de Bioénergétique Fondamentale et Appliquée, Institut National de la Santé et de la Recherche Médicale U1055, Grenoble, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Le Moual</LastName><ForeName>Nicole</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Severi</LastName><ForeName>Gianluca</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France; Team of Molecular and Genetic Epidemiology, Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and The University of Melbourne, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boutron-Ruault</LastName><ForeName>Marie-Christine</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France. Electronic address: marie-christine.boutron@gustaveroussy.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fournier</LastName><ForeName>Agnès</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Center for research in Epidemiology and Population Health (CESP), Unité Mixte de Recherche Scientifique 1018, Health Across Generation Team, Institut National de la Santé et de la Recherche Médicale, Villejuif, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bousquet</LastName><ForeName>Jean</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France; Clinique de Pneumologie, Centre Hospitalier Universitaire de Montpellier, Montpellier, France; MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bedouch</LastName><ForeName>Pierrick</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Pôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France; Facultés de Médecine et de Pharmacie, Université Grenoble Alpes, Grenoble, France; Equipe Techniques pour l'Evaluation et la Modélisation des Actions de Santé (ThEMAS), Centre National de la Recherche Scientifique, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications (TIMC-IMAG), Unité Mixte de Recherche 5525, Université Grenoble Alpes, Grenoble, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Varraso</LastName><ForeName>Raphaëlle</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>VIMA, Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Institut National de la Santé et de la Recherche Médicale U1168, Villejuif, France; Université Versailles St-Quentin-en-Yvelines, Unité Mixte de Recherche Scientifique 1168, Montigny le Bretonneux, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Siroux</LastName><ForeName>Valérie</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences, Institut National de la Santé et de la Recherche Médicale U1209, Centre National de la Recherche Scientifique - Unité Mixte de Recherche 5309, Université Grenoble Alpes, Grenoble, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>09</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Allergy Clin Immunol Pract</MedlineTA><NlmUniqueID>101597220</NlmUniqueID></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Asthma</Keyword><Keyword MajorTopicYN="N">Asthma medications</Keyword><Keyword MajorTopicYN="N">Asthma phenotypes</Keyword><Keyword MajorTopicYN="N">Drug claims data</Keyword><Keyword MajorTopicYN="N">Elderly people</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>01</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>07</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>07</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>9</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>9</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28958739</ArticleId><ArticleId IdType="pii">S2213-2198(17)30539-1</ArticleId><ArticleId IdType="doi">10.1016/j.jaip.2017.07.014</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>France</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Languedoc-Roussillon</li><li>Occitanie (région administrative)</li><li>Rhône-Alpes</li><li>Victoria (État)</li></region><settlement><li>Grenoble</li><li>Melbourne</li><li>Montpellier</li></settlement><orgName><li>Université Grenoble-Alpes</li><li>Université de Melbourne</li></orgName></list><tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Chanoine, Sebastien" sort="Chanoine, Sebastien" uniqKey="Chanoine S" first="Sébastien" last="Chanoine">Sébastien Chanoine</name></region><name sortKey="Bedouch, Pierrick" sort="Bedouch, Pierrick" uniqKey="Bedouch P" first="Pierrick" last="Bedouch">Pierrick Bedouch</name><name sortKey="Bousquet, Jean" sort="Bousquet, Jean" uniqKey="Bousquet J" first="Jean" last="Bousquet">Jean Bousquet</name><name sortKey="Boutron Ruault, Marie Christine" sort="Boutron Ruault, Marie Christine" uniqKey="Boutron Ruault M" first="Marie-Christine" last="Boutron-Ruault">Marie-Christine Boutron-Ruault</name><name sortKey="Fournier, Agnes" sort="Fournier, Agnes" uniqKey="Fournier A" first="Agnès" last="Fournier">Agnès Fournier</name><name sortKey="Le Moual, Nicole" sort="Le Moual, Nicole" uniqKey="Le Moual N" first="Nicole" last="Le Moual">Nicole Le Moual</name><name sortKey="Pin, Isabelle" sort="Pin, Isabelle" uniqKey="Pin I" first="Isabelle" last="Pin">Isabelle Pin</name><name sortKey="Pison, Christophe" sort="Pison, Christophe" uniqKey="Pison C" first="Christophe" last="Pison">Christophe Pison</name><name sortKey="Sanchez, Margaux" sort="Sanchez, Margaux" uniqKey="Sanchez M" first="Margaux" last="Sanchez">Margaux Sanchez</name><name sortKey="Siroux, Valerie" sort="Siroux, Valerie" uniqKey="Siroux V" first="Valérie" last="Siroux">Valérie Siroux</name><name sortKey="Temam, Sofia" sort="Temam, Sofia" uniqKey="Temam S" first="Sofia" last="Temam">Sofia Temam</name><name sortKey="Varraso, Raphaelle" sort="Varraso, Raphaelle" uniqKey="Varraso R" first="Raphaëlle" last="Varraso">Raphaëlle Varraso</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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