Changes in cortico-spinal excitability following uphill versus downhill treadmill exercise.
Identifieur interne : 001031 ( PubMed/Checkpoint ); précédent : 001030; suivant : 001032Changes in cortico-spinal excitability following uphill versus downhill treadmill exercise.
Auteurs : Yoann M. Garnier [France] ; Romuald Lepers [France] ; Paul J. Stapley [Australie] ; Charalambos Papaxanthis [France] ; Christos Paizis [France]Source :
- Behavioural brain research [ 1872-7549 ] ; 2017.
Abstract
An acute bout of aerobic exercise induces neuroplasticity in the motor cortex. Moreover, paired associative stimulation (PAS) is known to induce neuroplasticity in M1. However, the possible influence of the type of exercise on the neuroplastic changes remains unknown. The present study investigated the effects of two different modes of muscle contraction produced during locomotor exercise on changes in corticospinal (CS) excitability. Subjects performed two 30-min treadmill exercises at an intensity corresponding to 60% of their maximal heart rate with either a +10% (uphill) or -10% (downhill) slope. These exercises were followed or not by paired associative stimulation method (PAS25) which consisted of 200 paired stimuli (0.25Hz, 15min) of median nerve electrical stimulation followed by transcranial magnetic stimulation of the hand M1 area (ISI 25ms). Motor evoked potentials (MEP), assessed through abductor pollicis brevis (APB) activity were obtained before exercise, at 5min, 15min and 30min after exercise. A significant (P<0.05) increase of the MEP amplitude was observed 30min after both exercises but was not different between the two modes of locomotion. On the contrary, MEP amplitude with PAS25 increased only 30min after downhill exercise. We conclude that sub-maximal treadmill exercise increases CS excitability within a period of 30min. However, the predominant mode of muscle contraction during uphill versus downhill locomotion does not influence CS excitability when assessed using a non-exercised muscle. However, results from PAS25 suggest that specific neuroplastic changes occur likely due to homeostatic mechanisms induced by exercise plus a PAS protocol.
DOI: 10.1016/j.bbr.2016.09.051
PubMed: 27671075
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:27671075Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Changes in cortico-spinal excitability following uphill versus downhill treadmill exercise.</title><author><name sortKey="Garnier, Yoann M" sort="Garnier, Yoann M" uniqKey="Garnier Y" first="Yoann M" last="Garnier">Yoann M. Garnier</name><affiliation wicri:level="1"><nlm:affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: yoann.garnier@u-bourgogne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon</wicri:regionArea><wicri:noRegion>21000 Dijon</wicri:noRegion><wicri:noRegion>21000 Dijon</wicri:noRegion></affiliation></author><author><name sortKey="Lepers, Romuald" sort="Lepers, Romuald" uniqKey="Lepers R" first="Romuald" last="Lepers">Romuald Lepers</name><affiliation wicri:level="1"><nlm:affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: romuald.lepers@u-bourgogne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon</wicri:regionArea><wicri:noRegion>21000 Dijon</wicri:noRegion><wicri:noRegion>21000 Dijon</wicri:noRegion></affiliation></author><author><name sortKey="Stapley, Paul J" sort="Stapley, Paul J" uniqKey="Stapley P" first="Paul J" last="Stapley">Paul J. Stapley</name><affiliation wicri:level="1"><nlm:affiliation>Neural Control of Movement Laboratory, School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia. Electronic address: pstapley@uow.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neural Control of Movement Laboratory, School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Papaxanthis, Charalambos" sort="Papaxanthis, Charalambos" uniqKey="Papaxanthis C" first="Charalambos" last="Papaxanthis">Charalambos Papaxanthis</name><affiliation wicri:level="1"><nlm:affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: papaxant@u-bourgogne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon</wicri:regionArea><wicri:noRegion>21000 Dijon</wicri:noRegion><wicri:noRegion>21000 Dijon</wicri:noRegion></affiliation></author><author><name sortKey="Paizis, Christos" sort="Paizis, Christos" uniqKey="Paizis C" first="Christos" last="Paizis">Christos Paizis</name><affiliation wicri:level="1"><nlm:affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France; Centre for Performance Expertise, UFR STAPS, Université de Bourgogne Dijon, France. Electronic address: christos.paizis@u-bourgogne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France; Centre for Performance Expertise, UFR STAPS, Université de Bourgogne Dijon</wicri:regionArea><wicri:noRegion>Université de Bourgogne Dijon</wicri:noRegion><wicri:noRegion>Université de Bourgogne Dijon</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:27671075</idno><idno type="pmid">27671075</idno><idno type="doi">10.1016/j.bbr.2016.09.051</idno><idno type="wicri:Area/PubMed/Corpus">001269</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001269</idno><idno type="wicri:Area/PubMed/Curation">001258</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001258</idno><idno type="wicri:Area/PubMed/Checkpoint">001258</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001258</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Changes in cortico-spinal excitability following uphill versus downhill treadmill exercise.</title><author><name sortKey="Garnier, Yoann M" sort="Garnier, Yoann M" uniqKey="Garnier Y" first="Yoann M" last="Garnier">Yoann M. Garnier</name><affiliation wicri:level="3"><nlm:affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: yoann.garnier@u-bourgogne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon</wicri:regionArea><placeName><region type="region" nuts="2">Bourgogne-Franche-Comté</region><region type="old region" nuts="2">Bourgogne</region><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Lepers, Romuald" sort="Lepers, Romuald" uniqKey="Lepers R" first="Romuald" last="Lepers">Romuald Lepers</name><affiliation wicri:level="3"><nlm:affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: romuald.lepers@u-bourgogne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon</wicri:regionArea><placeName><region type="region" nuts="2">Bourgogne-Franche-Comté</region><region type="old region" nuts="2">Bourgogne</region><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Stapley, Paul J" sort="Stapley, Paul J" uniqKey="Stapley P" first="Paul J" last="Stapley">Paul J. Stapley</name><affiliation wicri:level="1"><nlm:affiliation>Neural Control of Movement Laboratory, School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia. Electronic address: pstapley@uow.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neural Control of Movement Laboratory, School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Papaxanthis, Charalambos" sort="Papaxanthis, Charalambos" uniqKey="Papaxanthis C" first="Charalambos" last="Papaxanthis">Charalambos Papaxanthis</name><affiliation wicri:level="1"><nlm:affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: papaxant@u-bourgogne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon</wicri:regionArea><wicri:noRegion>21000 Dijon</wicri:noRegion><wicri:noRegion>21000 Dijon</wicri:noRegion></affiliation></author><author><name sortKey="Paizis, Christos" sort="Paizis, Christos" uniqKey="Paizis C" first="Christos" last="Paizis">Christos Paizis</name><affiliation wicri:level="1"><nlm:affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France; Centre for Performance Expertise, UFR STAPS, Université de Bourgogne Dijon, France. Electronic address: christos.paizis@u-bourgogne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France; Centre for Performance Expertise, UFR STAPS, Université de Bourgogne Dijon</wicri:regionArea><wicri:noRegion>Université de Bourgogne Dijon</wicri:noRegion><wicri:noRegion>Université de Bourgogne Dijon</wicri:noRegion></affiliation></author></analytic><series><title level="j">Behavioural brain research</title><idno type="eISSN">1872-7549</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">An acute bout of aerobic exercise induces neuroplasticity in the motor cortex. Moreover, paired associative stimulation (PAS) is known to induce neuroplasticity in M1. However, the possible influence of the type of exercise on the neuroplastic changes remains unknown. The present study investigated the effects of two different modes of muscle contraction produced during locomotor exercise on changes in corticospinal (CS) excitability. Subjects performed two 30-min treadmill exercises at an intensity corresponding to 60% of their maximal heart rate with either a +10% (uphill) or -10% (downhill) slope. These exercises were followed or not by paired associative stimulation method (PAS25) which consisted of 200 paired stimuli (0.25Hz, 15min) of median nerve electrical stimulation followed by transcranial magnetic stimulation of the hand M1 area (ISI 25ms). Motor evoked potentials (MEP), assessed through abductor pollicis brevis (APB) activity were obtained before exercise, at 5min, 15min and 30min after exercise. A significant (P<0.05) increase of the MEP amplitude was observed 30min after both exercises but was not different between the two modes of locomotion. On the contrary, MEP amplitude with PAS25 increased only 30min after downhill exercise. We conclude that sub-maximal treadmill exercise increases CS excitability within a period of 30min. However, the predominant mode of muscle contraction during uphill versus downhill locomotion does not influence CS excitability when assessed using a non-exercised muscle. However, results from PAS25 suggest that specific neuroplastic changes occur likely due to homeostatic mechanisms induced by exercise plus a PAS protocol.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">27671075</PMID><DateCreated><Year>2016</Year><Month>09</Month><Day>30</Day></DateCreated><DateRevised><Year>2016</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1872-7549</ISSN><JournalIssue CitedMedium="Internet"><Volume>317</Volume><PubDate><Year>2017</Year><Month>Jan</Month><Day>15</Day></PubDate></JournalIssue><Title>Behavioural brain research</Title><ISOAbbreviation>Behav. Brain Res.</ISOAbbreviation></Journal><ArticleTitle>Changes in cortico-spinal excitability following uphill versus downhill treadmill exercise.</ArticleTitle><Pagination><MedlinePgn>242-250</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0166-4328(16)30700-8</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.bbr.2016.09.051</ELocationID><Abstract><AbstractText>An acute bout of aerobic exercise induces neuroplasticity in the motor cortex. Moreover, paired associative stimulation (PAS) is known to induce neuroplasticity in M1. However, the possible influence of the type of exercise on the neuroplastic changes remains unknown. The present study investigated the effects of two different modes of muscle contraction produced during locomotor exercise on changes in corticospinal (CS) excitability. Subjects performed two 30-min treadmill exercises at an intensity corresponding to 60% of their maximal heart rate with either a +10% (uphill) or -10% (downhill) slope. These exercises were followed or not by paired associative stimulation method (PAS25) which consisted of 200 paired stimuli (0.25Hz, 15min) of median nerve electrical stimulation followed by transcranial magnetic stimulation of the hand M1 area (ISI 25ms). Motor evoked potentials (MEP), assessed through abductor pollicis brevis (APB) activity were obtained before exercise, at 5min, 15min and 30min after exercise. A significant (P<0.05) increase of the MEP amplitude was observed 30min after both exercises but was not different between the two modes of locomotion. On the contrary, MEP amplitude with PAS25 increased only 30min after downhill exercise. We conclude that sub-maximal treadmill exercise increases CS excitability within a period of 30min. However, the predominant mode of muscle contraction during uphill versus downhill locomotion does not influence CS excitability when assessed using a non-exercised muscle. However, results from PAS25 suggest that specific neuroplastic changes occur likely due to homeostatic mechanisms induced by exercise plus a PAS protocol.</AbstractText><CopyrightInformation>Copyright © 2016 Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Garnier</LastName><ForeName>Yoann M</ForeName><Initials>YM</Initials><AffiliationInfo><Affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: yoann.garnier@u-bourgogne.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lepers</LastName><ForeName>Romuald</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: romuald.lepers@u-bourgogne.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stapley</LastName><ForeName>Paul J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Neural Control of Movement Laboratory, School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, Australia. Electronic address: pstapley@uow.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Papaxanthis</LastName><ForeName>Charalambos</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France. Electronic address: papaxant@u-bourgogne.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Paizis</LastName><ForeName>Christos</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>INSERM CAPS UMR 1093, F-21000 Dijon, France; University Bourgogne-Franche Comté, CAPS UMR 1093, F-21000 Dijon, France; Centre for Performance Expertise, UFR STAPS, Université de Bourgogne Dijon, France. Electronic address: christos.paizis@u-bourgogne.fr.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>09</Month><Day>23</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Behav Brain Res</MedlineTA><NlmUniqueID>8004872</NlmUniqueID><ISSNLinking>0166-4328</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Downhill</Keyword><Keyword MajorTopicYN="N">Paired associative stimulation</Keyword><Keyword MajorTopicYN="N">Transcranial magnetic stimulation</Keyword><Keyword MajorTopicYN="N">Treadmill running</Keyword><Keyword MajorTopicYN="N">Treadmill walking</Keyword><Keyword MajorTopicYN="N">Uphill</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>07</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>09</Month><Day>19</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>09</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>10</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>10</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>9</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27671075</ArticleId><ArticleId IdType="pii">S0166-4328(16)30700-8</ArticleId><ArticleId IdType="doi">10.1016/j.bbr.2016.09.051</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>France</li></country><region><li>Bourgogne</li><li>Bourgogne-Franche-Comté</li></region><settlement><li>Dijon</li></settlement></list><tree><country name="France"><region name="Bourgogne-Franche-Comté"><name sortKey="Garnier, Yoann M" sort="Garnier, Yoann M" uniqKey="Garnier Y" first="Yoann M" last="Garnier">Yoann M. Garnier</name></region><name sortKey="Lepers, Romuald" sort="Lepers, Romuald" uniqKey="Lepers R" first="Romuald" last="Lepers">Romuald Lepers</name><name sortKey="Paizis, Christos" sort="Paizis, Christos" uniqKey="Paizis C" first="Christos" last="Paizis">Christos Paizis</name><name sortKey="Papaxanthis, Charalambos" sort="Papaxanthis, Charalambos" uniqKey="Papaxanthis C" first="Charalambos" last="Papaxanthis">Charalambos Papaxanthis</name></country><country name="Australie"><noRegion><name sortKey="Stapley, Paul J" sort="Stapley, Paul J" uniqKey="Stapley P" first="Paul J" last="Stapley">Paul J. Stapley</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001031 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 001031 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:27671075
|texte= Changes in cortico-spinal excitability following uphill versus downhill treadmill exercise.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:27671075" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |