Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium.
Identifieur interne : 000F84 ( PubMed/Checkpoint ); précédent : 000F83; suivant : 000F85Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium.
Auteurs : Karen T. Putnam [États-Unis] ; Marsha Wilcox [États-Unis] ; Emma Robertson-Blackmore [États-Unis] ; Katherine Sharkey [États-Unis] ; Veerle Bergink [Pays-Bas] ; Trine Munk-Olsen [Danemark] ; Kristina M. Deligiannidis [États-Unis] ; Jennifer Payne [États-Unis] ; Margaret Altemus [États-Unis] ; Jeffrey Newport [États-Unis] ; Gisele Apter [France] ; Emmanuel Devouche [France] ; Alexander Viktorin [Suède] ; Patrik Magnusson [Suède] ; Brenda Penninx [Pays-Bas] ; Anne Buist [Australie] ; Justin Bilszta [Australie] ; Michael O'Hara [États-Unis] ; Scott Stuart [États-Unis] ; Rebecca Brock [États-Unis] ; Sabine Roza [Pays-Bas] ; Henning Tiemeier [Pays-Bas] ; Constance Guille [États-Unis] ; C Neill Epperson [États-Unis] ; Deborah Kim [États-Unis] ; Peter Schmidt [États-Unis] ; Pedro Martinez [États-Unis] ; Arianna Di Florio [Royaume-Uni] ; Katherine L. Wisner [États-Unis] ; Zachary Stowe [États-Unis] ; Ian Jones [Royaume-Uni] ; Patrick F. Sullivan [Suède] ; David Rubinow [États-Unis] ; Kevin Wildenhaus [États-Unis] ; Samantha Meltzer-Brody [États-Unis]Source :
- The lancet. Psychiatry [ 2215-0374 ] ; 2017.
Abstract
The perinatal period is a time of high risk for onset of depressive disorders and is associated with substantial morbidity and mortality, including maternal suicide. Perinatal depression comprises a heterogeneous group of clinical subtypes, and further refinement is needed to improve treatment outcomes. We sought to empirically identify and describe clinically relevant phenotypic subtypes of perinatal depression, and further characterise subtypes by time of symptom onset within pregnancy and three post-partum periods.
DOI: 10.1016/S2215-0366(17)30136-0
PubMed: 28476427
Affiliations:
- Australie, Danemark, France, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Arkansas, Caroline du Nord, Caroline du Sud, Floride, Hollande-Méridionale, Hollande-Septentrionale, Illinois, Iowa, Maryland, New Jersey, Pennsylvanie, Rhode Island, Svealand, Victoria (État), État de New York, Île-de-France
- Amsterdam, Chapel Hill (Caroline du Nord), Iowa City, Melbourne, Paris, Providence (Rhode Island), Rotterdam, Stockholm
- Université Brown, Université de Caroline du Nord à Chapel Hill, Université de Melbourne, Université de l'Iowa
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of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Penninx, Brenda" sort="Penninx, Brenda" uniqKey="Penninx B" first="Brenda" last="Penninx">Brenda Penninx</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry, VU University Medical Center, Amsterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, VU University Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Buist, Anne" 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type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="O Hara, Michael" sort="O Hara, Michael" uniqKey="O Hara M" first="Michael" last="O'Hara">Michael O'Hara</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Iowa, Iowa City, IA</wicri:regionArea><placeName><region type="state">Iowa</region><settlement type="city">Iowa City</settlement></placeName><orgName type="university">Université de l'Iowa</orgName></affiliation></author><author><name sortKey="Stuart, Scott" sort="Stuart, Scott" uniqKey="Stuart S" first="Scott" last="Stuart">Scott Stuart</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Iowa, Iowa City, IA</wicri:regionArea><placeName><region type="state">Iowa</region><settlement type="city">Iowa City</settlement></placeName><orgName type="university">Université de l'Iowa</orgName></affiliation></author><author><name sortKey="Brock, Rebecca" sort="Brock, Rebecca" uniqKey="Brock R" first="Rebecca" last="Brock">Rebecca Brock</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Iowa, Iowa City, IA</wicri:regionArea><placeName><region type="state">Iowa</region><settlement type="city">Iowa City</settlement></placeName><orgName type="university">Université de l'Iowa</orgName></affiliation></author><author><name sortKey="Roza, Sabine" sort="Roza, Sabine" uniqKey="Roza S" first="Sabine" last="Roza">Sabine Roza</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Tiemeier, Henning" sort="Tiemeier, Henning" uniqKey="Tiemeier H" first="Henning" last="Tiemeier">Henning Tiemeier</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Guille, Constance" sort="Guille, Constance" uniqKey="Guille C" first="Constance" last="Guille">Constance Guille</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, Medical University of South Carolina, Charleston, SC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Medical University of South Carolina, Charleston, SC</wicri:regionArea><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Epperson, C Neill" sort="Epperson, C Neill" uniqKey="Epperson C" first="C Neill" last="Epperson">C Neill Epperson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Kim, Deborah" sort="Kim, Deborah" uniqKey="Kim D" first="Deborah" last="Kim">Deborah Kim</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Schmidt, Peter" sort="Schmidt, Peter" uniqKey="Schmidt P" first="Peter" last="Schmidt">Peter Schmidt</name><affiliation wicri:level="2"><nlm:affiliation>National Institutes of Mental Health, Bethesda, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institutes of Mental Health, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Martinez, Pedro" sort="Martinez, Pedro" uniqKey="Martinez P" first="Pedro" last="Martinez">Pedro Martinez</name><affiliation wicri:level="2"><nlm:affiliation>National Institutes of Mental Health, Bethesda, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institutes of Mental Health, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Di Florio, Arianna" sort="Di Florio, Arianna" uniqKey="Di Florio A" first="Arianna" last="Di Florio">Arianna Di Florio</name><affiliation wicri:level="1"><nlm:affiliation>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Wisner, Katherine L" sort="Wisner, Katherine L" uniqKey="Wisner K" first="Katherine L" last="Wisner">Katherine L. Wisner</name><affiliation wicri:level="2"><nlm:affiliation>Northwestern University Feinberg School of Medicine, Asher Center for the Study and Treatment of Depressive Disorders, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Northwestern University Feinberg School of Medicine, Asher Center for the Study and Treatment of Depressive Disorders, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Stowe, Zachary" sort="Stowe, Zachary" uniqKey="Stowe Z" first="Zachary" last="Stowe">Zachary Stowe</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR</wicri:regionArea><placeName><region type="state">Arkansas</region></placeName></affiliation></author><author><name sortKey="Jones, Ian" sort="Jones, Ian" uniqKey="Jones I" first="Ian" last="Jones">Ian Jones</name><affiliation wicri:level="1"><nlm:affiliation>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Sullivan, Patrick F" sort="Sullivan, Patrick F" uniqKey="Sullivan P" first="Patrick F" last="Sullivan">Patrick F. Sullivan</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Rubinow, David" sort="Rubinow, David" uniqKey="Rubinow D" first="David" last="Rubinow">David Rubinow</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Wildenhaus, Kevin" sort="Wildenhaus, Kevin" uniqKey="Wildenhaus K" first="Kevin" last="Wildenhaus">Kevin Wildenhaus</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research & Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research & Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Meltzer Brody, Samantha" sort="Meltzer Brody, Samantha" uniqKey="Meltzer Brody S" first="Samantha" last="Meltzer-Brody">Samantha Meltzer-Brody</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: meltzerb@med.unc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28476427</idno><idno type="pmid">28476427</idno><idno type="doi">10.1016/S2215-0366(17)30136-0</idno><idno type="wicri:Area/PubMed/Corpus">000A49</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A49</idno><idno type="wicri:Area/PubMed/Curation">000A46</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A46</idno><idno type="wicri:Area/PubMed/Checkpoint">000A46</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A46</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium.</title><author><name sortKey="Putnam, Karen T" sort="Putnam, Karen T" uniqKey="Putnam K" first="Karen T" last="Putnam">Karen T. Putnam</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Wilcox, Marsha" sort="Wilcox, Marsha" uniqKey="Wilcox M" first="Marsha" last="Wilcox">Marsha Wilcox</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research & Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research & Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Robertson Blackmore, Emma" sort="Robertson Blackmore, Emma" uniqKey="Robertson Blackmore E" first="Emma" last="Robertson-Blackmore">Emma Robertson-Blackmore</name><affiliation wicri:level="2"><nlm:affiliation>Family Medicine Residency, Halifax Health, Daytona Beach, FL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Family Medicine Residency, Halifax Health, Daytona Beach, FL</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Sharkey, Katherine" sort="Sharkey, Katherine" uniqKey="Sharkey K" first="Katherine" last="Sharkey">Katherine Sharkey</name><affiliation wicri:level="4"><nlm:affiliation>Department of Internal Medicine and Psychiatry, Brown University, Providence, RI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine and Psychiatry, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Bergink, Veerle" sort="Bergink, Veerle" uniqKey="Bergink V" first="Veerle" last="Bergink">Veerle Bergink</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Munk Olsen, Trine" sort="Munk Olsen, Trine" uniqKey="Munk Olsen T" first="Trine" last="Munk-Olsen">Trine Munk-Olsen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Economics and Business-National Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Economics and Business-National Centre for Integrated Register-based Research, Aarhus University, Aarhus</wicri:regionArea><wicri:noRegion>Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Deligiannidis, Kristina M" sort="Deligiannidis, Kristina M" uniqKey="Deligiannidis K" first="Kristina M" last="Deligiannidis">Kristina M. Deligiannidis</name><affiliation wicri:level="2"><nlm:affiliation>Departments of Psychiatry and Obstetrics and Gynecology, Hofstra Northwell School of Medicine, Glen Oaks, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Departments of Psychiatry and Obstetrics and Gynecology, Hofstra Northwell School of Medicine, Glen Oaks, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Payne, Jennifer" sort="Payne, Jennifer" uniqKey="Payne J" first="Jennifer" last="Payne">Jennifer Payne</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Johns Hopkins University, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Altemus, Margaret" sort="Altemus, Margaret" uniqKey="Altemus M" first="Margaret" last="Altemus">Margaret Altemus</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, Weill Cornell Medical College, New York City, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Weill Cornell Medical College, New York City, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Newport, Jeffrey" sort="Newport, Jeffrey" uniqKey="Newport J" first="Jeffrey" last="Newport">Jeffrey Newport</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of Miami, Miami, FL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Miami, Miami, FL</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Apter, Gisele" sort="Apter, Gisele" uniqKey="Apter G" first="Gisele" last="Apter">Gisele Apter</name><affiliation wicri:level="3"><nlm:affiliation>Erasme Hospital, Paris Diderot University, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Erasme Hospital, Paris Diderot University, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Devouche, Emmanuel" sort="Devouche, Emmanuel" uniqKey="Devouche E" first="Emmanuel" last="Devouche">Emmanuel Devouche</name><affiliation wicri:level="3"><nlm:affiliation>Erasme Hospital, Paris Descartes University, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Erasme Hospital, Paris Descartes University, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Viktorin, Alexander" sort="Viktorin, Alexander" uniqKey="Viktorin A" first="Alexander" last="Viktorin">Alexander Viktorin</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Magnusson, Patrik" sort="Magnusson, Patrik" uniqKey="Magnusson P" first="Patrik" last="Magnusson">Patrik Magnusson</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Penninx, Brenda" sort="Penninx, Brenda" uniqKey="Penninx B" first="Brenda" last="Penninx">Brenda Penninx</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry, VU University Medical Center, Amsterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, VU University Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Buist, Anne" sort="Buist, Anne" uniqKey="Buist A" first="Anne" last="Buist">Anne Buist</name><affiliation wicri:level="4"><nlm:affiliation>University of Melbourne, Women's Mental Health, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Melbourne, Women's Mental Health, Melbourne, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Bilszta, Justin" sort="Bilszta, Justin" uniqKey="Bilszta J" first="Justin" last="Bilszta">Justin Bilszta</name><affiliation wicri:level="4"><nlm:affiliation>University of Melbourne, Women's Mental Health, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>University of Melbourne, Women's Mental Health, Melbourne, VIC</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="O Hara, Michael" sort="O Hara, Michael" uniqKey="O Hara M" first="Michael" last="O'Hara">Michael O'Hara</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Iowa, Iowa City, IA</wicri:regionArea><placeName><region type="state">Iowa</region><settlement type="city">Iowa City</settlement></placeName><orgName type="university">Université de l'Iowa</orgName></affiliation></author><author><name sortKey="Stuart, Scott" sort="Stuart, Scott" uniqKey="Stuart S" first="Scott" last="Stuart">Scott Stuart</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Iowa, Iowa City, IA</wicri:regionArea><placeName><region type="state">Iowa</region><settlement type="city">Iowa City</settlement></placeName><orgName type="university">Université de l'Iowa</orgName></affiliation></author><author><name sortKey="Brock, Rebecca" sort="Brock, Rebecca" uniqKey="Brock R" first="Rebecca" last="Brock">Rebecca Brock</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of Iowa, Iowa City, IA</wicri:regionArea><placeName><region type="state">Iowa</region><settlement type="city">Iowa City</settlement></placeName><orgName type="university">Université de l'Iowa</orgName></affiliation></author><author><name sortKey="Roza, Sabine" sort="Roza, Sabine" uniqKey="Roza S" first="Sabine" last="Roza">Sabine Roza</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Tiemeier, Henning" sort="Tiemeier, Henning" uniqKey="Tiemeier H" first="Henning" last="Tiemeier">Henning Tiemeier</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Guille, Constance" sort="Guille, Constance" uniqKey="Guille C" first="Constance" last="Guille">Constance Guille</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, Medical University of South Carolina, Charleston, SC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Medical University of South Carolina, Charleston, SC</wicri:regionArea><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Epperson, C Neill" sort="Epperson, C Neill" uniqKey="Epperson C" first="C Neill" last="Epperson">C Neill Epperson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Kim, Deborah" sort="Kim, Deborah" uniqKey="Kim D" first="Deborah" last="Kim">Deborah Kim</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Schmidt, Peter" sort="Schmidt, Peter" uniqKey="Schmidt P" first="Peter" last="Schmidt">Peter Schmidt</name><affiliation wicri:level="2"><nlm:affiliation>National Institutes of Mental Health, Bethesda, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institutes of Mental Health, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Martinez, Pedro" sort="Martinez, Pedro" uniqKey="Martinez P" first="Pedro" last="Martinez">Pedro Martinez</name><affiliation wicri:level="2"><nlm:affiliation>National Institutes of Mental Health, Bethesda, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institutes of Mental Health, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Di Florio, Arianna" sort="Di Florio, Arianna" uniqKey="Di Florio A" first="Arianna" last="Di Florio">Arianna Di Florio</name><affiliation wicri:level="1"><nlm:affiliation>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Wisner, Katherine L" sort="Wisner, Katherine L" uniqKey="Wisner K" first="Katherine L" last="Wisner">Katherine L. Wisner</name><affiliation wicri:level="2"><nlm:affiliation>Northwestern University Feinberg School of Medicine, Asher Center for the Study and Treatment of Depressive Disorders, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Northwestern University Feinberg School of Medicine, Asher Center for the Study and Treatment of Depressive Disorders, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Stowe, Zachary" sort="Stowe, Zachary" uniqKey="Stowe Z" first="Zachary" last="Stowe">Zachary Stowe</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR</wicri:regionArea><placeName><region type="state">Arkansas</region></placeName></affiliation></author><author><name sortKey="Jones, Ian" sort="Jones, Ian" uniqKey="Jones I" first="Ian" last="Jones">Ian Jones</name><affiliation wicri:level="1"><nlm:affiliation>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Sullivan, Patrick F" sort="Sullivan, Patrick F" uniqKey="Sullivan P" first="Patrick F" last="Sullivan">Patrick F. Sullivan</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Rubinow, David" sort="Rubinow, David" uniqKey="Rubinow D" first="David" last="Rubinow">David Rubinow</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Wildenhaus, Kevin" sort="Wildenhaus, Kevin" uniqKey="Wildenhaus K" first="Kevin" last="Wildenhaus">Kevin Wildenhaus</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research & Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research & Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Meltzer Brody, Samantha" sort="Meltzer Brody, Samantha" uniqKey="Meltzer Brody S" first="Samantha" last="Meltzer-Brody">Samantha Meltzer-Brody</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: meltzerb@med.unc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author></analytic><series><title level="j">The lancet. Psychiatry</title><idno type="eISSN">2215-0374</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The perinatal period is a time of high risk for onset of depressive disorders and is associated with substantial morbidity and mortality, including maternal suicide. Perinatal depression comprises a heterogeneous group of clinical subtypes, and further refinement is needed to improve treatment outcomes. We sought to empirically identify and describe clinically relevant phenotypic subtypes of perinatal depression, and further characterise subtypes by time of symptom onset within pregnancy and three post-partum periods.</div></front></TEI><pubmed><MedlineCitation Status="In-Data-Review" Owner="NLM"><PMID Version="1">28476427</PMID><DateCreated><Year>2017</Year><Month>05</Month><Day>06</Day></DateCreated><DateRevised><Year>2017</Year><Month>09</Month><Day>23</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2215-0374</ISSN><JournalIssue CitedMedium="Internet"><Volume>4</Volume><Issue>6</Issue><PubDate><Year>2017</Year><Month>Jun</Month></PubDate></JournalIssue><Title>The lancet. Psychiatry</Title><ISOAbbreviation>Lancet Psychiatry</ISOAbbreviation></Journal><ArticleTitle>Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium.</ArticleTitle><Pagination><MedlinePgn>477-485</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S2215-0366(17)30136-0</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/S2215-0366(17)30136-0</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The perinatal period is a time of high risk for onset of depressive disorders and is associated with substantial morbidity and mortality, including maternal suicide. Perinatal depression comprises a heterogeneous group of clinical subtypes, and further refinement is needed to improve treatment outcomes. We sought to empirically identify and describe clinically relevant phenotypic subtypes of perinatal depression, and further characterise subtypes by time of symptom onset within pregnancy and three post-partum periods.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Data were assembled from a subset of seven of 19 international sites in the Postpartum Depression: Action Towards Causes and Treatment (PACT) Consortium. In this analysis, the cohort was restricted to women aged 19-40 years with information about onset of depressive symptoms in the perinatal period and complete prospective data for the ten-item Edinburgh postnatal depression scale (EPDS). Principal components and common factor analysis were used to identify symptom dimensions in the EPDS. The National Institute of Mental Health research domain criteria functional constructs of negative valence and arousal were applied to the EPDS dimensions that reflect states of depressed mood, anhedonia, and anxiety. We used k-means clustering to identify subtypes of women sharing symptom patterns. Univariate and bivariate statistics were used to describe the subtypes.</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">Data for 663 women were included in these analyses. We found evidence for three underlying dimensions measured by the EPDS: depressed mood, anxiety, and anhedonia. On the basis of these dimensions, we identified five distinct subtypes of perinatal depression: severe anxious depression, moderate anxious depression, anxious anhedonia, pure anhedonia, and resolved depression. These subtypes have clear differences in symptom quality and time of onset. Anxiety and anhedonia emerged as prominent symptom dimensions with post-partum onset and were notably severe.</AbstractText><AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">Our findings show that there might be different types and severity of perinatal depression with varying time of onset throughout pregnancy and post partum. These findings support the need for tailored treatments that improve outcomes for women with perinatal depression.</AbstractText><AbstractText Label="FUNDING" NlmCategory="BACKGROUND">Janssen Research & Development.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Putnam</LastName><ForeName>Karen T</ForeName><Initials>KT</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wilcox</LastName><ForeName>Marsha</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Janssen Research & Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Robertson-Blackmore</LastName><ForeName>Emma</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Family Medicine Residency, Halifax Health, Daytona Beach, FL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sharkey</LastName><ForeName>Katherine</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine and Psychiatry, Brown University, Providence, RI, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bergink</LastName><ForeName>Veerle</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Munk-Olsen</LastName><ForeName>Trine</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Economics and Business-National Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Deligiannidis</LastName><ForeName>Kristina M</ForeName><Initials>KM</Initials><AffiliationInfo><Affiliation>Departments of Psychiatry and Obstetrics and Gynecology, Hofstra Northwell School of Medicine, Glen Oaks, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Payne</LastName><ForeName>Jennifer</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Altemus</LastName><ForeName>Margaret</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, Weill Cornell Medical College, New York City, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Newport</LastName><ForeName>Jeffrey</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of Miami, Miami, FL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Apter</LastName><ForeName>Gisele</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Erasme Hospital, Paris Diderot University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Devouche</LastName><ForeName>Emmanuel</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Erasme Hospital, Paris Descartes University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Viktorin</LastName><ForeName>Alexander</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Magnusson</LastName><ForeName>Patrik</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Penninx</LastName><ForeName>Brenda</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, VU University Medical Center, Amsterdam, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buist</LastName><ForeName>Anne</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>University of Melbourne, Women's Mental Health, Melbourne, VIC, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bilszta</LastName><ForeName>Justin</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>University of Melbourne, Women's Mental Health, Melbourne, VIC, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Hara</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stuart</LastName><ForeName>Scott</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brock</LastName><ForeName>Rebecca</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Iowa, Iowa City, IA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roza</LastName><ForeName>Sabine</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tiemeier</LastName><ForeName>Henning</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Psychiatry/Psychology, Erasmus MC, Rotterdam, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guille</LastName><ForeName>Constance</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, Medical University of South Carolina, Charleston, SC, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Epperson</LastName><ForeName>C Neill</ForeName><Initials>CN</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Deborah</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>National Institutes of Mental Health, Bethesda, MD, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martinez</LastName><ForeName>Pedro</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>National Institutes of Mental Health, Bethesda, MD, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Di Florio</LastName><ForeName>Arianna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wisner</LastName><ForeName>Katherine L</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Northwestern University Feinberg School of Medicine, Asher Center for the Study and Treatment of Depressive Disorders, Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stowe</LastName><ForeName>Zachary</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jones</LastName><ForeName>Ian</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, Cardiff, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sullivan</LastName><ForeName>Patrick F</ForeName><Initials>PF</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rubinow</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wildenhaus</LastName><ForeName>Kevin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Janssen Research & Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meltzer-Brody</LastName><ForeName>Samantha</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: meltzerb@med.unc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>Postpartum Depression: Action Towards Causes and Treatment (PACT) Consortium</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>K23 MH097794</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>L30 MH104713</GrantID><Acronym>MH</Acronym><Agency>NIMH NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>UL1 TR000161</GrantID><Acronym>TR</Acronym><Agency>NCATS NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>05</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Lancet Psychiatry</MedlineTA><NlmUniqueID>101638123</NlmUniqueID><ISSNLinking>2215-0366</ISSNLinking></MedlineJournalInfo></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>10</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>03</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>03</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>5</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>5</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>5</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28476427</ArticleId><ArticleId IdType="pii">S2215-0366(17)30136-0</ArticleId><ArticleId IdType="doi">10.1016/S2215-0366(17)30136-0</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>Danemark</li><li>France</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Arkansas</li><li>Caroline du Nord</li><li>Caroline du Sud</li><li>Floride</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Illinois</li><li>Iowa</li><li>Maryland</li><li>New Jersey</li><li>Pennsylvanie</li><li>Rhode Island</li><li>Svealand</li><li>Victoria (État)</li><li>État de New York</li><li>Île-de-France</li></region><settlement><li>Amsterdam</li><li>Chapel Hill (Caroline du Nord)</li><li>Iowa City</li><li>Melbourne</li><li>Paris</li><li>Providence (Rhode Island)</li><li>Rotterdam</li><li>Stockholm</li></settlement><orgName><li>Université Brown</li><li>Université de Caroline du Nord à Chapel Hill</li><li>Université de Melbourne</li><li>Université de l'Iowa</li></orgName></list><tree><country name="États-Unis"><region name="Caroline du Nord"><name sortKey="Putnam, Karen T" sort="Putnam, Karen T" uniqKey="Putnam K" first="Karen T" last="Putnam">Karen T. Putnam</name></region><name sortKey="Altemus, Margaret" sort="Altemus, Margaret" uniqKey="Altemus M" first="Margaret" last="Altemus">Margaret Altemus</name><name sortKey="Brock, Rebecca" sort="Brock, Rebecca" uniqKey="Brock R" first="Rebecca" last="Brock">Rebecca Brock</name><name sortKey="Deligiannidis, Kristina M" sort="Deligiannidis, Kristina M" uniqKey="Deligiannidis K" first="Kristina M" last="Deligiannidis">Kristina M. Deligiannidis</name><name sortKey="Epperson, C Neill" sort="Epperson, C Neill" uniqKey="Epperson C" first="C Neill" last="Epperson">C Neill Epperson</name><name sortKey="Guille, Constance" sort="Guille, Constance" uniqKey="Guille C" first="Constance" last="Guille">Constance Guille</name><name sortKey="Kim, Deborah" sort="Kim, Deborah" uniqKey="Kim D" first="Deborah" last="Kim">Deborah Kim</name><name sortKey="Martinez, Pedro" sort="Martinez, Pedro" uniqKey="Martinez P" first="Pedro" last="Martinez">Pedro Martinez</name><name sortKey="Meltzer Brody, Samantha" sort="Meltzer Brody, Samantha" uniqKey="Meltzer Brody S" first="Samantha" last="Meltzer-Brody">Samantha Meltzer-Brody</name><name sortKey="Newport, Jeffrey" sort="Newport, Jeffrey" uniqKey="Newport J" first="Jeffrey" last="Newport">Jeffrey Newport</name><name sortKey="O Hara, Michael" sort="O Hara, Michael" uniqKey="O Hara M" first="Michael" last="O'Hara">Michael O'Hara</name><name sortKey="Payne, Jennifer" sort="Payne, Jennifer" uniqKey="Payne J" first="Jennifer" last="Payne">Jennifer Payne</name><name sortKey="Robertson Blackmore, Emma" sort="Robertson Blackmore, Emma" uniqKey="Robertson Blackmore E" first="Emma" last="Robertson-Blackmore">Emma Robertson-Blackmore</name><name sortKey="Rubinow, David" sort="Rubinow, David" uniqKey="Rubinow D" first="David" last="Rubinow">David Rubinow</name><name sortKey="Schmidt, Peter" sort="Schmidt, Peter" uniqKey="Schmidt P" first="Peter" last="Schmidt">Peter Schmidt</name><name sortKey="Sharkey, Katherine" sort="Sharkey, Katherine" uniqKey="Sharkey K" first="Katherine" last="Sharkey">Katherine Sharkey</name><name sortKey="Stowe, Zachary" sort="Stowe, Zachary" uniqKey="Stowe Z" first="Zachary" last="Stowe">Zachary Stowe</name><name sortKey="Stuart, Scott" sort="Stuart, Scott" uniqKey="Stuart S" first="Scott" last="Stuart">Scott Stuart</name><name sortKey="Wilcox, Marsha" sort="Wilcox, Marsha" uniqKey="Wilcox M" first="Marsha" last="Wilcox">Marsha Wilcox</name><name sortKey="Wildenhaus, Kevin" sort="Wildenhaus, Kevin" uniqKey="Wildenhaus K" first="Kevin" last="Wildenhaus">Kevin Wildenhaus</name><name sortKey="Wisner, Katherine L" sort="Wisner, Katherine L" uniqKey="Wisner K" first="Katherine L" last="Wisner">Katherine L. Wisner</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Bergink, Veerle" sort="Bergink, Veerle" uniqKey="Bergink V" first="Veerle" last="Bergink">Veerle Bergink</name></region><name sortKey="Penninx, Brenda" sort="Penninx, Brenda" uniqKey="Penninx B" first="Brenda" last="Penninx">Brenda Penninx</name><name sortKey="Roza, Sabine" sort="Roza, Sabine" uniqKey="Roza S" first="Sabine" last="Roza">Sabine Roza</name><name sortKey="Tiemeier, Henning" sort="Tiemeier, Henning" uniqKey="Tiemeier H" first="Henning" last="Tiemeier">Henning Tiemeier</name></country><country name="Danemark"><noRegion><name sortKey="Munk Olsen, Trine" sort="Munk Olsen, Trine" uniqKey="Munk Olsen T" first="Trine" last="Munk-Olsen">Trine Munk-Olsen</name></noRegion></country><country name="France"><region name="Île-de-France"><name sortKey="Apter, Gisele" sort="Apter, Gisele" uniqKey="Apter G" first="Gisele" last="Apter">Gisele Apter</name></region><name sortKey="Devouche, Emmanuel" sort="Devouche, Emmanuel" uniqKey="Devouche E" first="Emmanuel" last="Devouche">Emmanuel Devouche</name></country><country name="Suède"><region name="Svealand"><name sortKey="Viktorin, Alexander" sort="Viktorin, Alexander" uniqKey="Viktorin A" first="Alexander" last="Viktorin">Alexander Viktorin</name></region><name sortKey="Magnusson, Patrik" sort="Magnusson, Patrik" uniqKey="Magnusson P" first="Patrik" last="Magnusson">Patrik Magnusson</name><name sortKey="Sullivan, Patrick F" sort="Sullivan, Patrick F" uniqKey="Sullivan P" first="Patrick F" last="Sullivan">Patrick F. Sullivan</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Buist, Anne" sort="Buist, Anne" uniqKey="Buist A" first="Anne" last="Buist">Anne Buist</name></region><name sortKey="Bilszta, Justin" sort="Bilszta, Justin" uniqKey="Bilszta J" first="Justin" last="Bilszta">Justin Bilszta</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Di Florio, Arianna" sort="Di Florio, Arianna" uniqKey="Di Florio A" first="Arianna" last="Di Florio">Arianna Di Florio</name></noRegion><name sortKey="Jones, Ian" sort="Jones, Ian" uniqKey="Jones I" first="Ian" last="Jones">Ian Jones</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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