Geographic variation and risk factors for systemic and limb ischemic events in patients with symptomatic peripheral artery disease: Insights from the REACH Registry.
Identifieur interne : 000B56 ( PubMed/Checkpoint ); précédent : 000B55; suivant : 000B57Geographic variation and risk factors for systemic and limb ischemic events in patients with symptomatic peripheral artery disease: Insights from the REACH Registry.
Auteurs : Jérémie Abtan [France] ; Deepak L. Bhatt [États-Unis] ; Yedid Elbez [France] ; Emmanuel Sorbets [France] ; Kim Eagle [États-Unis] ; Christopher M. Reid [Australie] ; Iris Baumgartner [Suisse] ; David Wu [États-Unis] ; Mary E. Hanson [États-Unis] ; Hakima Hannachi [États-Unis] ; Puneet K. Singhal [États-Unis] ; Philippe Gabriel Steg [France] ; Gregory Ducrocq [France]Source :
- Clinical cardiology [ 1932-8737 ] ; 2017.
Abstract
Patients with symptomatic peripheral artery disease (PAD) are at high risk of ischemic events. However, data about predictors of this risk are limited.
DOI: 10.1002/clc.22721
PubMed: 28520087
Affiliations:
- Australie, France, Suisse, États-Unis
- Australie-Occidentale, Canton de Berne, Massachusetts, Michigan, New Jersey
- Berne
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Singhal</name><affiliation wicri:level="2"><nlm:affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Merck & Co., Inc., Kenilworth</wicri:cityArea></affiliation></author><author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name><affiliation wicri:level="1"><nlm:affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris</wicri:regionArea><wicri:noRegion>U-1148 Paris</wicri:noRegion><wicri:noRegion>U-1148 Paris</wicri:noRegion></affiliation></author><author><name sortKey="Ducrocq, Gregory" sort="Ducrocq, Gregory" uniqKey="Ducrocq G" first="Gregory" last="Ducrocq">Gregory Ducrocq</name><affiliation wicri:level="1"><nlm:affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris</wicri:regionArea><wicri:noRegion>U-1148 Paris</wicri:noRegion><wicri:noRegion>U-1148 Paris</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28520087</idno><idno type="pmid">28520087</idno><idno type="doi">10.1002/clc.22721</idno><idno type="wicri:Area/PubMed/Corpus">000652</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000652</idno><idno type="wicri:Area/PubMed/Curation">000650</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000650</idno><idno type="wicri:Area/PubMed/Checkpoint">000650</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000650</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Geographic variation and risk factors for systemic and limb ischemic events in patients with symptomatic peripheral artery disease: Insights from the REACH Registry.</title><author><name sortKey="Abtan, Jeremie" sort="Abtan, Jeremie" uniqKey="Abtan J" first="Jérémie" last="Abtan">Jérémie Abtan</name><affiliation wicri:level="1"><nlm:affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris</wicri:regionArea><wicri:noRegion>U-1148 Paris</wicri:noRegion><wicri:noRegion>U-1148 Paris</wicri:noRegion></affiliation></author><author><name sortKey="Bhatt, Deepak L" sort="Bhatt, Deepak L" uniqKey="Bhatt D" first="Deepak L" last="Bhatt">Deepak L. Bhatt</name><affiliation wicri:level="2"><nlm:affiliation>Heart and Vascular Center, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Heart and Vascular Center, Brigham and Women's Hospital, and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Elbez, Yedid" sort="Elbez, Yedid" uniqKey="Elbez Y" first="Yedid" last="Elbez">Yedid Elbez</name><affiliation wicri:level="1"><nlm:affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris</wicri:regionArea><wicri:noRegion>U-1148 Paris</wicri:noRegion><wicri:noRegion>U-1148 Paris</wicri:noRegion></affiliation></author><author><name sortKey="Sorbets, Emmanuel" sort="Sorbets, Emmanuel" uniqKey="Sorbets E" first="Emmanuel" last="Sorbets">Emmanuel Sorbets</name><affiliation wicri:level="1"><nlm:affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris</wicri:regionArea><wicri:noRegion>U-1148 Paris</wicri:noRegion><wicri:noRegion>U-1148 Paris</wicri:noRegion></affiliation></author><author><name sortKey="Eagle, Kim" sort="Eagle, Kim" uniqKey="Eagle K" first="Kim" last="Eagle">Kim Eagle</name><affiliation wicri:level="2"><nlm:affiliation>Cardiovascular Center, University of Michigan, Ann Arbor, Michigan.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Michigan</region></placeName><wicri:cityArea>Cardiovascular Center, University of Michigan, Ann Arbor</wicri:cityArea></affiliation></author><author><name sortKey="Reid, Christopher M" sort="Reid, Christopher M" uniqKey="Reid C" first="Christopher M" last="Reid">Christopher M. Reid</name><affiliation wicri:level="2"><nlm:affiliation>Monash University, Clayton, Victoria, Australia and Curtin University, Bentley, Perth, Western Australia.</nlm:affiliation><country>Australie</country><placeName><region type="state">Australie-Occidentale</region></placeName><wicri:cityArea>Monash University, Clayton, Victoria, Australia and Curtin University, Bentley, Perth</wicri:cityArea></affiliation></author><author><name sortKey="Baumgartner, Iris" sort="Baumgartner, Iris" uniqKey="Baumgartner I" first="Iris" last="Baumgartner">Iris Baumgartner</name><affiliation wicri:level="3"><nlm:affiliation>University Hospital of Bern, Bern, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>University Hospital of Bern, Bern</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region type="région" nuts="3">Canton de Berne</region></placeName></affiliation></author><author><name sortKey="Wu, David" sort="Wu, David" uniqKey="Wu D" first="David" last="Wu">David Wu</name><affiliation wicri:level="2"><nlm:affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Merck & Co., Inc., Kenilworth</wicri:cityArea></affiliation></author><author><name sortKey="Hanson, Mary E" sort="Hanson, Mary E" uniqKey="Hanson M" first="Mary E" last="Hanson">Mary E. Hanson</name><affiliation wicri:level="2"><nlm:affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Merck & Co., Inc., Kenilworth</wicri:cityArea></affiliation></author><author><name sortKey="Hannachi, Hakima" sort="Hannachi, Hakima" uniqKey="Hannachi H" first="Hakima" last="Hannachi">Hakima Hannachi</name><affiliation wicri:level="2"><nlm:affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Merck & Co., Inc., Kenilworth</wicri:cityArea></affiliation></author><author><name sortKey="Singhal, Puneet K" sort="Singhal, Puneet K" uniqKey="Singhal P" first="Puneet K" last="Singhal">Puneet K. Singhal</name><affiliation wicri:level="2"><nlm:affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">New Jersey</region></placeName><wicri:cityArea>Merck & Co., Inc., Kenilworth</wicri:cityArea></affiliation></author><author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name><affiliation wicri:level="1"><nlm:affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris</wicri:regionArea><wicri:noRegion>U-1148 Paris</wicri:noRegion><wicri:noRegion>U-1148 Paris</wicri:noRegion></affiliation></author><author><name sortKey="Ducrocq, Gregory" sort="Ducrocq, Gregory" uniqKey="Ducrocq G" first="Gregory" last="Ducrocq">Gregory Ducrocq</name><affiliation wicri:level="1"><nlm:affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris</wicri:regionArea><wicri:noRegion>U-1148 Paris</wicri:noRegion><wicri:noRegion>U-1148 Paris</wicri:noRegion></affiliation></author></analytic><series><title level="j">Clinical cardiology</title><idno type="eISSN">1932-8737</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Patients with symptomatic peripheral artery disease (PAD) are at high risk of ischemic events. However, data about predictors of this risk are limited.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28520087</PMID><DateCreated><Year>2017</Year><Month>05</Month><Day>18</Day></DateCreated><DateRevised><Year>2017</Year><Month>09</Month><Day>23</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1932-8737</ISSN><JournalIssue CitedMedium="Internet"><Volume>40</Volume><Issue>9</Issue><PubDate><Year>2017</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Clinical cardiology</Title><ISOAbbreviation>Clin Cardiol</ISOAbbreviation></Journal><ArticleTitle>Geographic variation and risk factors for systemic and limb ischemic events in patients with symptomatic peripheral artery disease: Insights from the REACH Registry.</ArticleTitle><Pagination><MedlinePgn>710-718</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/clc.22721</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Patients with symptomatic peripheral artery disease (PAD) are at high risk of ischemic events. However, data about predictors of this risk are limited.</AbstractText><AbstractText Label="HYPOTHESIS" NlmCategory="OBJECTIVE">We analyzed baseline characteristics and 4-year follow-up of patients enrolled in the international REduction of Atherothrombosis for Continued Health (REACH) Registry with symptomatic PAD and no history of stroke/transient ischemic attack to describe annual rates of recurrent ischemic events globally and geographically.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The primary outcome was systemic ischemic events (composite of cardiovascular death, myocardial infarction, or stroke) at 4 years. The secondary outcome was limb ischemic events (composite of lower limb amputation, peripheral bypass graft, and percutaneous intervention for PAD) at 2 years. Multivariate analysis identified risk factors associated with recurrent ischemic events.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The primary endpoint rate reached 4.7% during the first year and increased continuously (by 4%-5% each year) to 17.6% by year 4, driven mainly by cardiovascular mortality (11.1% at year 4). Japan experienced lower adjusted ischemic rates (P < 0.01) vs North America. Renal impairment (P < 0.01), congestive heart failure (P < 0.01), history of diabetes (P < 0.01), history of myocardial infarction (P = 0.01), vascular disease (single or poly, P < 0.01), and older age (P < 0.01) were associated with increased risk of systemic ischemic events, whereas statin use was associated with lower risk (P = 0.03). The limb ischemic event rate was 5.7% at 2 years.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Four-year systemic ischemic risk in patients with PAD and no history of stroke or transient ischemic attack remains high, and was mainly driven by cardiovascular mortality.</AbstractText><CopyrightInformation>© 2017 Wiley Periodicals, Inc.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Abtan</LastName><ForeName>Jérémie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bhatt</LastName><ForeName>Deepak L</ForeName><Initials>DL</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-1278-6245</Identifier><AffiliationInfo><Affiliation>Heart and Vascular Center, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Elbez</LastName><ForeName>Yedid</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sorbets</LastName><ForeName>Emmanuel</ForeName><Initials>E</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-0559-6301</Identifier><AffiliationInfo><Affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Avicenne Hospital Hôpital, Public Assistance Hospitals of Paris, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eagle</LastName><ForeName>Kim</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Cardiovascular Center, University of Michigan, Ann Arbor, Michigan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Reid</LastName><ForeName>Christopher M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Monash University, Clayton, Victoria, Australia and Curtin University, Bentley, Perth, Western Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baumgartner</LastName><ForeName>Iris</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>University Hospital of Bern, Bern, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wu</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hanson</LastName><ForeName>Mary E</ForeName><Initials>ME</Initials><Identifier Source="ORCID">http://orcid.org/0000-0003-4785-7207</Identifier><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hannachi</LastName><ForeName>Hakima</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Singhal</LastName><ForeName>Puneet K</ForeName><Initials>PK</Initials><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steg</LastName><ForeName>Philippe Gabriel</ForeName><Initials>PG</Initials><AffiliationInfo><Affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>National Heart and Lung Institute, Imperial College School of Medicine, Royal Brompton Hospital, Imperial College, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ducrocq</LastName><ForeName>Gregory</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>FACT (French Alliance for Cardiovascular Trials), French Clinical Research Infrastructure Network, University Hospital Departments-FIRE, Hôpital Bichat, Public Assistance Hospitals of Paris, Paris Diderot University, Sorbonne University Paris Cité, and National Institute of Health and Medical Research, U-1148 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>REACH Registry Investigators</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>05</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Clin Cardiol</MedlineTA><NlmUniqueID>7903272</NlmUniqueID><ISSNLinking>0160-9289</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Ischemic Risk</Keyword><Keyword MajorTopicYN="N">Peripheral Artery Disease</Keyword><Keyword MajorTopicYN="N">Vorapaxar</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>01</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>03</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>03</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>5</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>5</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>5</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28520087</ArticleId><ArticleId IdType="doi">10.1002/clc.22721</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>France</li><li>Suisse</li><li>États-Unis</li></country><region><li>Australie-Occidentale</li><li>Canton de Berne</li><li>Massachusetts</li><li>Michigan</li><li>New Jersey</li></region><settlement><li>Berne</li></settlement></list><tree><country name="France"><noRegion><name sortKey="Abtan, Jeremie" sort="Abtan, Jeremie" uniqKey="Abtan J" first="Jérémie" last="Abtan">Jérémie Abtan</name></noRegion><name sortKey="Ducrocq, Gregory" sort="Ducrocq, Gregory" uniqKey="Ducrocq G" first="Gregory" last="Ducrocq">Gregory Ducrocq</name><name sortKey="Elbez, Yedid" sort="Elbez, Yedid" uniqKey="Elbez Y" first="Yedid" last="Elbez">Yedid Elbez</name><name sortKey="Sorbets, Emmanuel" sort="Sorbets, Emmanuel" uniqKey="Sorbets E" first="Emmanuel" last="Sorbets">Emmanuel Sorbets</name><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Bhatt, Deepak L" sort="Bhatt, Deepak L" uniqKey="Bhatt D" first="Deepak L" last="Bhatt">Deepak L. Bhatt</name></region><name sortKey="Eagle, Kim" sort="Eagle, Kim" uniqKey="Eagle K" first="Kim" last="Eagle">Kim Eagle</name><name sortKey="Hannachi, Hakima" sort="Hannachi, Hakima" uniqKey="Hannachi H" first="Hakima" last="Hannachi">Hakima Hannachi</name><name sortKey="Hanson, Mary E" sort="Hanson, Mary E" uniqKey="Hanson M" first="Mary E" last="Hanson">Mary E. Hanson</name><name sortKey="Singhal, Puneet K" sort="Singhal, Puneet K" uniqKey="Singhal P" first="Puneet K" last="Singhal">Puneet K. Singhal</name><name sortKey="Wu, David" sort="Wu, David" uniqKey="Wu D" first="David" last="Wu">David Wu</name></country><country name="Australie"><region name="Australie-Occidentale"><name sortKey="Reid, Christopher M" sort="Reid, Christopher M" uniqKey="Reid C" first="Christopher M" last="Reid">Christopher M. Reid</name></region></country><country name="Suisse"><region name="Canton de Berne"><name sortKey="Baumgartner, Iris" sort="Baumgartner, Iris" uniqKey="Baumgartner I" first="Iris" last="Baumgartner">Iris Baumgartner</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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