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Implications of Intrahepatic Cholangiocarcinoma Etiology on Recurrence and Prognosis after Curative-Intent Resection: a Multi-Institutional Study.

Identifieur interne : 000A14 ( PubMed/Checkpoint ); précédent : 000A13; suivant : 000A15

Implications of Intrahepatic Cholangiocarcinoma Etiology on Recurrence and Prognosis after Curative-Intent Resection: a Multi-Institutional Study.

Auteurs : Xu-Feng Zhang [République populaire de Chine] ; Jeffery Chakedis [États-Unis] ; Fabio Bagante [Italie] ; Eliza W. Beal [États-Unis] ; Yi Lv [République populaire de Chine] ; Matthew Weiss [États-Unis] ; Irinel Popescu [Roumanie] ; Hugo P. Marques [Portugal] ; Luca Aldrighetti [Italie] ; Shishir K. Maithel [États-Unis] ; Carlo Pulitano [Australie] ; Todd W. Bauer [États-Unis] ; Feng Shen [République populaire de Chine] ; George A. Poultsides [États-Unis] ; Oliver Soubrane [France] ; Guillaume Martel [Canada] ; B. Groot Koerkamp [Pays-Bas] ; Alfredo Guglielmi [Italie] ; Endo Itaru [Japon] ; Timothy M. Pawlik [États-Unis]

Source :

RBID : pubmed:28879598

Abstract

We sought to investigate the prognosis of patients following curative-intent surgery for intrahepatic cholangiocarcinoma (ICC) stratified by hepatitis B (HBV-ICC), hepatolithiasis (Stone-ICC), and no identifiable cause (conventional ICC) etiologic subtype.

DOI: 10.1007/s00268-017-4199-9
PubMed: 28879598


Affiliations:


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pubmed:28879598

Le document en format XML

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<nlm:affiliation>Department of Surgery, Erasmus University Medical Centre, Rotterdam, Netherlands.</nlm:affiliation>
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<name sortKey="Guglielmi, Alfredo" sort="Guglielmi, Alfredo" uniqKey="Guglielmi A" first="Alfredo" last="Guglielmi">Alfredo Guglielmi</name>
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<name sortKey="Itaru, Endo" sort="Itaru, Endo" uniqKey="Itaru E" first="Endo" last="Itaru">Endo Itaru</name>
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<name sortKey="Pawlik, Timothy M" sort="Pawlik, Timothy M" uniqKey="Pawlik T" first="Timothy M" last="Pawlik">Timothy M. Pawlik</name>
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<title xml:lang="en">Implications of Intrahepatic Cholangiocarcinoma Etiology on Recurrence and Prognosis after Curative-Intent Resection: a Multi-Institutional Study.</title>
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<name sortKey="Zhang, Xu Feng" sort="Zhang, Xu Feng" uniqKey="Zhang X" first="Xu-Feng" last="Zhang">Xu-Feng Zhang</name>
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<nlm:affiliation>Department of Hepatobiliary Surgery and Institute of Advanced Surgical Technology and Engineering, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
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<name sortKey="Chakedis, Jeffery" sort="Chakedis, Jeffery" uniqKey="Chakedis J" first="Jeffery" last="Chakedis">Jeffery Chakedis</name>
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<nlm:affiliation>Department of Surgery, The Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, Suite 670, Columbus, OH, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Surgery, The Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, Suite 670, Columbus, OH</wicri:regionArea>
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<name sortKey="Bagante, Fabio" sort="Bagante, Fabio" uniqKey="Bagante F" first="Fabio" last="Bagante">Fabio Bagante</name>
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<nlm:affiliation>Department of Surgery, University of Verona, Verona, Italy.</nlm:affiliation>
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<name sortKey="Beal, Eliza W" sort="Beal, Eliza W" uniqKey="Beal E" first="Eliza W" last="Beal">Eliza W. Beal</name>
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<nlm:affiliation>Department of Surgery, The Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, Suite 670, Columbus, OH, USA.</nlm:affiliation>
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<name sortKey="Lv, Yi" sort="Lv, Yi" uniqKey="Lv Y" first="Yi" last="Lv">Yi Lv</name>
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<nlm:affiliation>Department of Hepatobiliary Surgery and Institute of Advanced Surgical Technology and Engineering, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.</nlm:affiliation>
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<name sortKey="Weiss, Matthew" sort="Weiss, Matthew" uniqKey="Weiss M" first="Matthew" last="Weiss">Matthew Weiss</name>
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<nlm:affiliation>Department of Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.</nlm:affiliation>
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<name sortKey="Popescu, Irinel" sort="Popescu, Irinel" uniqKey="Popescu I" first="Irinel" last="Popescu">Irinel Popescu</name>
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<nlm:affiliation>Department of Surgery, Fundeni Clinical Institute, Bucharest, Romania.</nlm:affiliation>
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<name sortKey="Marques, Hugo P" sort="Marques, Hugo P" uniqKey="Marques H" first="Hugo P" last="Marques">Hugo P. Marques</name>
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<nlm:affiliation>Department of Surgery, Curry Cabral Hospital, Lisbon, Portugal.</nlm:affiliation>
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<name sortKey="Aldrighetti, Luca" sort="Aldrighetti, Luca" uniqKey="Aldrighetti L" first="Luca" last="Aldrighetti">Luca Aldrighetti</name>
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<name sortKey="Maithel, Shishir K" sort="Maithel, Shishir K" uniqKey="Maithel S" first="Shishir K" last="Maithel">Shishir K. Maithel</name>
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<nlm:affiliation>Department of Surgery, Emory University, Atlanta, GA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Surgery, Emory University, Atlanta, GA</wicri:regionArea>
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</placeName>
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<name sortKey="Pulitano, Carlo" sort="Pulitano, Carlo" uniqKey="Pulitano C" first="Carlo" last="Pulitano">Carlo Pulitano</name>
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<nlm:affiliation>Department of Surgery, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Surgery, Royal Prince Alfred Hospital, University of Sydney, Sydney</wicri:regionArea>
<placeName>
<settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
</affiliation>
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<name sortKey="Bauer, Todd W" sort="Bauer, Todd W" uniqKey="Bauer T" first="Todd W" last="Bauer">Todd W. Bauer</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Surgery, University of Virginia, Charlottesville, VA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Surgery, University of Virginia, Charlottesville, VA</wicri:regionArea>
<placeName>
<region type="state">Virginie</region>
</placeName>
</affiliation>
</author>
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<name sortKey="Shen, Feng" sort="Shen, Feng" uniqKey="Shen F" first="Feng" last="Shen">Feng Shen</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Surgery, Eastern Hepatobiliary Surgery Hospital, Shanghai, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Surgery, Eastern Hepatobiliary Surgery Hospital, Shanghai</wicri:regionArea>
<wicri:noRegion>Shanghai</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Poultsides, George A" sort="Poultsides, George A" uniqKey="Poultsides G" first="George A" last="Poultsides">George A. Poultsides</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Surgery, Stanford University, Stanford, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Surgery, Stanford University, Stanford, CA</wicri:regionArea>
<placeName>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Soubrane, Oliver" sort="Soubrane, Oliver" uniqKey="Soubrane O" first="Oliver" last="Soubrane">Oliver Soubrane</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Hepatobiliopancreatic Surgery and Liver Transplantation, AP-HP, Beaujon Hospital, Clichy, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Hepatobiliopancreatic Surgery and Liver Transplantation, AP-HP, Beaujon Hospital, Clichy</wicri:regionArea>
<wicri:noRegion>Clichy</wicri:noRegion>
<wicri:noRegion>Clichy</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Martel, Guillaume" sort="Martel, Guillaume" uniqKey="Martel G" first="Guillaume" last="Martel">Guillaume Martel</name>
<affiliation wicri:level="1">
<nlm:affiliation>Division of General Surgery, Department of Surgery, University of Ottawa, Ottawa, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of General Surgery, Department of Surgery, University of Ottawa, Ottawa, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
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<name sortKey="Groot Koerkamp, B" sort="Groot Koerkamp, B" uniqKey="Groot Koerkamp B" first="B" last="Groot Koerkamp">B. Groot Koerkamp</name>
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<nlm:affiliation>Department of Surgery, Erasmus University Medical Centre, Rotterdam, Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Surgery, Erasmus University Medical Centre, Rotterdam</wicri:regionArea>
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<settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
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<author>
<name sortKey="Guglielmi, Alfredo" sort="Guglielmi, Alfredo" uniqKey="Guglielmi A" first="Alfredo" last="Guglielmi">Alfredo Guglielmi</name>
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<nlm:affiliation>Department of Surgery, University of Verona, Verona, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Surgery, University of Verona, Verona</wicri:regionArea>
<wicri:noRegion>Verona</wicri:noRegion>
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</author>
<author>
<name sortKey="Itaru, Endo" sort="Itaru, Endo" uniqKey="Itaru E" first="Endo" last="Itaru">Endo Itaru</name>
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<nlm:affiliation>Gastroenterological Surgery Division, Yokohama City University School of Medicine, Yokohama, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Gastroenterological Surgery Division, Yokohama City University School of Medicine, Yokohama</wicri:regionArea>
<wicri:noRegion>Yokohama</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Pawlik, Timothy M" sort="Pawlik, Timothy M" uniqKey="Pawlik T" first="Timothy M" last="Pawlik">Timothy M. Pawlik</name>
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<nlm:affiliation>Department of Surgery, The Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, Suite 670, Columbus, OH, USA. tim.pawlik@osumc.edu.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Surgery, The Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, Suite 670, Columbus, OH</wicri:regionArea>
<placeName>
<region type="state">Ohio</region>
</placeName>
</affiliation>
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</analytic>
<series>
<title level="j">World journal of surgery</title>
<idno type="eISSN">1432-2323</idno>
<imprint>
<date when="2017" type="published">2017</date>
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<front>
<div type="abstract" xml:lang="en">We sought to investigate the prognosis of patients following curative-intent surgery for intrahepatic cholangiocarcinoma (ICC) stratified by hepatitis B (HBV-ICC), hepatolithiasis (Stone-ICC), and no identifiable cause (conventional ICC) etiologic subtype.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="Publisher" Owner="NLM">
<PMID Version="1">28879598</PMID>
<DateCreated>
<Year>2017</Year>
<Month>09</Month>
<Day>07</Day>
</DateCreated>
<DateRevised>
<Year>2017</Year>
<Month>09</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1432-2323</ISSN>
<JournalIssue CitedMedium="Internet">
<PubDate>
<Year>2017</Year>
<Month>Sep</Month>
<Day>06</Day>
</PubDate>
</JournalIssue>
<Title>World journal of surgery</Title>
<ISOAbbreviation>World J Surg</ISOAbbreviation>
</Journal>
<ArticleTitle>Implications of Intrahepatic Cholangiocarcinoma Etiology on Recurrence and Prognosis after Curative-Intent Resection: a Multi-Institutional Study.</ArticleTitle>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s00268-017-4199-9</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">We sought to investigate the prognosis of patients following curative-intent surgery for intrahepatic cholangiocarcinoma (ICC) stratified by hepatitis B (HBV-ICC), hepatolithiasis (Stone-ICC), and no identifiable cause (conventional ICC) etiologic subtype.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">986 patients with HBV-ICC (n = 201), stone-ICC (n = 103), and conventional ICC (n = 682) who underwent curative-intent resection were identified from a multi-institutional database. Propensity score matching (PSM) was used to mitigate residual bias.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">HBV-ICC patients more often had cirrhosis, earlier stage tumors, a mass-forming lesion, well-to-moderate tumor differentiation, and an R0 resection versus stone-ICC or conventional ICC patients. Five-year recurrence-free survival among HBV-ICC and conventional ICC patients was 23.9 and 17.8%, respectively, versus a recurrence-free of only 8.3% among patients with stone-ICC. Similarly, 5-year overall survival among patients with stone-ICC was only 18.3% compared with 48.9 and 38.0% for patients with HBV-ICC and conventional ICC, respectively. On PSM, patients with stone-ICC group had equivalent long-term outcomes as HBV-ICC patients. In contrast, on PSM, stone-ICC patients had a median overall survival of only 18.0 months versus 44.0 months for patients with conventional ICC. Median overall survival after intrahepatic-only recurrence among patients who had stone-ICC (6.0 months) was worse than OS among HBV-ICC (13.0 months) or conventional ICC (12.0 months) (p = 0.006 and p = 0.082, respectively).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">While HBV-ICC had a better prognosis on unadjusted analyses, these differences were mitigated on PSM suggesting no stage-for-stage differences in outcomes compared with stone-ICC or conventional ICC. In contrast, patients with stone-ICC had worse long-term outcomes. These data highlight the relative importance of ICC etiology relative to established clinicopathological factors in the prognosis of patients with ICC.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Zhang</LastName>
<ForeName>Xu-Feng</ForeName>
<Initials>XF</Initials>
<AffiliationInfo>
<Affiliation>Department of Hepatobiliary Surgery and Institute of Advanced Surgical Technology and Engineering, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Surgery, The Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, Suite 670, Columbus, OH, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Chakedis</LastName>
<ForeName>Jeffery</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Surgery, The Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, Suite 670, Columbus, OH, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Bagante</LastName>
<ForeName>Fabio</ForeName>
<Initials>F</Initials>
<AffiliationInfo>
<Affiliation>Department of Surgery, University of Verona, Verona, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Beal</LastName>
<ForeName>Eliza W</ForeName>
<Initials>EW</Initials>
<AffiliationInfo>
<Affiliation>Department of Surgery, The Ohio State University, Wexner Medical Center, 395 W. 12th Avenue, Suite 670, Columbus, OH, USA.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Lv</LastName>
<ForeName>Yi</ForeName>
<Initials>Y</Initials>
<AffiliationInfo>
<Affiliation>Department of Hepatobiliary Surgery and Institute of Advanced Surgical Technology and Engineering, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Weiss</LastName>
<ForeName>Matthew</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Popescu</LastName>
<ForeName>Irinel</ForeName>
<Initials>I</Initials>
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<Affiliation>Department of Surgery, Fundeni Clinical Institute, Bucharest, Romania.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Marques</LastName>
<ForeName>Hugo P</ForeName>
<Initials>HP</Initials>
<AffiliationInfo>
<Affiliation>Department of Surgery, Curry Cabral Hospital, Lisbon, Portugal.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Aldrighetti</LastName>
<ForeName>Luca</ForeName>
<Initials>L</Initials>
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<Affiliation>Department of Surgery, Ospedale San Raffaele, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Maithel</LastName>
<ForeName>Shishir K</ForeName>
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</AffiliationInfo>
</Author>
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<LastName>Pulitano</LastName>
<ForeName>Carlo</ForeName>
<Initials>C</Initials>
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</AffiliationInfo>
</Author>
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</AffiliationInfo>
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<LastName>Shen</LastName>
<ForeName>Feng</ForeName>
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</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Poultsides</LastName>
<ForeName>George A</ForeName>
<Initials>GA</Initials>
<AffiliationInfo>
<Affiliation>Department of Surgery, Stanford University, Stanford, CA, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Soubrane</LastName>
<ForeName>Oliver</ForeName>
<Initials>O</Initials>
<AffiliationInfo>
<Affiliation>Department of Hepatobiliopancreatic Surgery and Liver Transplantation, AP-HP, Beaujon Hospital, Clichy, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Martel</LastName>
<ForeName>Guillaume</ForeName>
<Initials>G</Initials>
<AffiliationInfo>
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</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Groot Koerkamp</LastName>
<ForeName>B</ForeName>
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<Month>09</Month>
<Day>06</Day>
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<li>France</li>
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