Improved Neonatal Mortality at a District Hospital in Aweil, South Sudan.
Identifieur interne : 000A12 ( PubMed/Checkpoint ); précédent : 000A11; suivant : 000A13Improved Neonatal Mortality at a District Hospital in Aweil, South Sudan.
Auteurs : Johanna Thomson [France] ; Myrto Schaefer [Australie] ; Belen Caminoa [Australie] ; David Kahindi [Soudan du Sud] ; Northan Hurtado [États-Unis]Source :
- Journal of tropical pediatrics [ 1465-3664 ] ; 2017.
Abstract
Neonatal deaths comprise a growing proportion of global under-five mortality. However, data from the highest-burden areas is sparse. This descriptive retrospective study analyses the outcomes of all infants exiting the Médecins sans Frontières-managed neonatal unit in Aweil Hospital, rural South Sudan from 2011 to 2014. A total of 4268 patients were treated over 4 years, with annual admissions increasing from 687 to 1494. Overall mortality was 13.5% (n = 576), declining from 18.7% to 11.1% (p for trend <0.001). Newborns weighing <2500 g were at significantly increased mortality risk compared with babies ≥2500 g (odds ratio = 2.27, 95% confidence interval = 1.9-2.71, p < 0.001). Leading causes of death included sepsis (49.7%), tetanus (15.8%), respiratory distress (12.8%) and asphyxia (9.2%). Tetanus had the highest case fatality rate (49.7%), followed by perinatal asphyxia (26.5%), respiratory distress (20.4%) and neonatal sepsis (10.5%). Despite increasing admissions, overall mortality declined, indicating that survival of these especially vulnerable infants can be improved even in a basic-level district hospital programme.
DOI: 10.1093/tropej/fmw071
PubMed: 27789662
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:27789662Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Improved Neonatal Mortality at a District Hospital in Aweil, South Sudan.</title><author><name sortKey="Thomson, Johanna" sort="Thomson, Johanna" uniqKey="Thomson J" first="Johanna" last="Thomson">Johanna Thomson</name><affiliation wicri:level="1"><nlm:affiliation>Médecins Sans Frontières, Paris, 75011, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Médecins Sans Frontières, Paris, 75011</wicri:regionArea><wicri:noRegion>75011</wicri:noRegion><wicri:noRegion>75011</wicri:noRegion></affiliation></author><author><name sortKey="Schaefer, Myrto" sort="Schaefer, Myrto" uniqKey="Schaefer M" first="Myrto" last="Schaefer">Myrto Schaefer</name><affiliation wicri:level="1"><nlm:affiliation>Médecins Sans Frontières, Sydney, 2037, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Médecins Sans Frontières, Sydney, 2037</wicri:regionArea><wicri:noRegion>2037</wicri:noRegion></affiliation></author><author><name sortKey="Caminoa, Belen" sort="Caminoa, Belen" uniqKey="Caminoa B" first="Belen" last="Caminoa">Belen Caminoa</name><affiliation wicri:level="1"><nlm:affiliation>Médecins Sans Frontières, Sydney, 2037, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Médecins Sans Frontières, Sydney, 2037</wicri:regionArea><wicri:noRegion>2037</wicri:noRegion></affiliation></author><author><name sortKey="Kahindi, David" sort="Kahindi, David" uniqKey="Kahindi D" first="David" last="Kahindi">David Kahindi</name><affiliation wicri:level="1"><nlm:affiliation>Medical Co-ordination, Médecins Sans Frontières, Juba, South Sudan.</nlm:affiliation><country xml:lang="fr">Soudan du Sud</country><wicri:regionArea>Medical Co-ordination, Médecins Sans Frontières, Juba</wicri:regionArea><wicri:noRegion>Juba</wicri:noRegion></affiliation></author><author><name sortKey="Hurtado, Northan" sort="Hurtado, Northan" uniqKey="Hurtado N" first="Northan" last="Hurtado">Northan Hurtado</name><affiliation wicri:level="1"><nlm:affiliation>Médecins Sans Frontières, NY, 10001-5004, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Médecins Sans Frontières, NY, 10001-5004</wicri:regionArea><wicri:noRegion>10001-5004</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:27789662</idno><idno type="pmid">27789662</idno><idno type="doi">10.1093/tropej/fmw071</idno><idno type="wicri:Area/PubMed/Corpus">000A82</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A82</idno><idno type="wicri:Area/PubMed/Curation">000A79</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A79</idno><idno type="wicri:Area/PubMed/Checkpoint">000A79</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A79</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Improved Neonatal Mortality at a District Hospital in Aweil, South Sudan.</title><author><name sortKey="Thomson, Johanna" sort="Thomson, Johanna" uniqKey="Thomson J" first="Johanna" last="Thomson">Johanna Thomson</name><affiliation wicri:level="3"><nlm:affiliation>Médecins Sans Frontières, Paris, 75011, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Médecins Sans Frontières, Paris, 75011</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Schaefer, Myrto" sort="Schaefer, Myrto" uniqKey="Schaefer M" first="Myrto" last="Schaefer">Myrto Schaefer</name><affiliation wicri:level="1"><nlm:affiliation>Médecins Sans Frontières, Sydney, 2037, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Médecins Sans Frontières, Sydney, 2037</wicri:regionArea><wicri:noRegion>2037</wicri:noRegion></affiliation></author><author><name sortKey="Caminoa, Belen" sort="Caminoa, Belen" uniqKey="Caminoa B" first="Belen" last="Caminoa">Belen Caminoa</name><affiliation wicri:level="1"><nlm:affiliation>Médecins Sans Frontières, Sydney, 2037, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Médecins Sans Frontières, Sydney, 2037</wicri:regionArea><wicri:noRegion>2037</wicri:noRegion></affiliation></author><author><name sortKey="Kahindi, David" sort="Kahindi, David" uniqKey="Kahindi D" first="David" last="Kahindi">David Kahindi</name><affiliation wicri:level="1"><nlm:affiliation>Medical Co-ordination, Médecins Sans Frontières, Juba, South Sudan.</nlm:affiliation><country xml:lang="fr">Soudan du Sud</country><wicri:regionArea>Medical Co-ordination, Médecins Sans Frontières, Juba</wicri:regionArea><wicri:noRegion>Juba</wicri:noRegion></affiliation></author><author><name sortKey="Hurtado, Northan" sort="Hurtado, Northan" uniqKey="Hurtado N" first="Northan" last="Hurtado">Northan Hurtado</name><affiliation wicri:level="1"><nlm:affiliation>Médecins Sans Frontières, NY, 10001-5004, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Médecins Sans Frontières, NY, 10001-5004</wicri:regionArea><wicri:noRegion>10001-5004</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of tropical pediatrics</title><idno type="eISSN">1465-3664</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Neonatal deaths comprise a growing proportion of global under-five mortality. However, data from the highest-burden areas is sparse. This descriptive retrospective study analyses the outcomes of all infants exiting the Médecins sans Frontières-managed neonatal unit in Aweil Hospital, rural South Sudan from 2011 to 2014. A total of 4268 patients were treated over 4 years, with annual admissions increasing from 687 to 1494. Overall mortality was 13.5% (n = 576), declining from 18.7% to 11.1% (p for trend <0.001). Newborns weighing <2500 g were at significantly increased mortality risk compared with babies ≥2500 g (odds ratio = 2.27, 95% confidence interval = 1.9-2.71, p < 0.001). Leading causes of death included sepsis (49.7%), tetanus (15.8%), respiratory distress (12.8%) and asphyxia (9.2%). Tetanus had the highest case fatality rate (49.7%), followed by perinatal asphyxia (26.5%), respiratory distress (20.4%) and neonatal sepsis (10.5%). Despite increasing admissions, overall mortality declined, indicating that survival of these especially vulnerable infants can be improved even in a basic-level district hospital programme.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">27789662</PMID><DateCreated><Year>2016</Year><Month>10</Month><Day>28</Day></DateCreated><DateRevised><Year>2017</Year><Month>06</Month><Day>04</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1465-3664</ISSN><JournalIssue CitedMedium="Internet"><Volume>63</Volume><Issue>3</Issue><PubDate><Year>2017</Year><Month>Jun</Month><Day>01</Day></PubDate></JournalIssue><Title>Journal of tropical pediatrics</Title><ISOAbbreviation>J. Trop. Pediatr.</ISOAbbreviation></Journal><ArticleTitle>Improved Neonatal Mortality at a District Hospital in Aweil, South Sudan.</ArticleTitle><Pagination><MedlinePgn>189-195</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/tropej/fmw071</ELocationID><Abstract><AbstractText>Neonatal deaths comprise a growing proportion of global under-five mortality. However, data from the highest-burden areas is sparse. This descriptive retrospective study analyses the outcomes of all infants exiting the Médecins sans Frontières-managed neonatal unit in Aweil Hospital, rural South Sudan from 2011 to 2014. A total of 4268 patients were treated over 4 years, with annual admissions increasing from 687 to 1494. Overall mortality was 13.5% (n = 576), declining from 18.7% to 11.1% (p for trend <0.001). Newborns weighing <2500 g were at significantly increased mortality risk compared with babies ≥2500 g (odds ratio = 2.27, 95% confidence interval = 1.9-2.71, p < 0.001). Leading causes of death included sepsis (49.7%), tetanus (15.8%), respiratory distress (12.8%) and asphyxia (9.2%). Tetanus had the highest case fatality rate (49.7%), followed by perinatal asphyxia (26.5%), respiratory distress (20.4%) and neonatal sepsis (10.5%). Despite increasing admissions, overall mortality declined, indicating that survival of these especially vulnerable infants can be improved even in a basic-level district hospital programme.</AbstractText><CopyrightInformation>© The Author [2016]. Published by Oxford University Press.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Thomson</LastName><ForeName>Johanna</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Médecins Sans Frontières, Paris, 75011, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Field Epidemiology and Training, Epicentre, Paris, 75011, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schaefer</LastName><ForeName>Myrto</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Médecins Sans Frontières, Sydney, 2037, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Caminoa</LastName><ForeName>Belen</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Médecins Sans Frontières, Sydney, 2037, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kahindi</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Medical Co-ordination, Médecins Sans Frontières, Juba, South Sudan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hurtado</LastName><ForeName>Northan</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Médecins Sans Frontières, NY, 10001-5004, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Trop Pediatr</MedlineTA><NlmUniqueID>8010948</NlmUniqueID><ISSNLinking>0142-6338</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Trop Doct. 2007 Jul;37(3):130-2</RefSource><PMID Version="1">17716492</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2012 Feb 4;379(9814):445-52</RefSource><PMID Version="1">22244654</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Res Notes. 2016 Jan 16;9:28</RefSource><PMID Version="1">26774269</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Trop Paediatr. 2003 Dec;23(4):293-9</RefSource><PMID Version="1">14738577</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Paediatr Int Child Health. 2014 Feb;34(1):3-11</RefSource><PMID Version="1">24165032</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Niger J Clin Pract. 2009 Dec;12(4):389-94</RefSource><PMID Version="1">20329678</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Niger J Clin Pract. 2010 Sep;13(3):321-5</RefSource><PMID Version="1">20857794</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Trop Pediatr. 2003 Jun;49(3):148-52</RefSource><PMID Version="1">12848203</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Trop Paediatr. 2011;31(1):59-65</RefSource><PMID Version="1">21262111</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Trop Pediatr. 2006 Aug;52(4):249-53</RefSource><PMID Version="1">16326752</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2014 Aug 2;384(9941):455-67</RefSource><PMID Version="1">24853599</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Public Health. 2010 Oct 06;10:591</RefSource><PMID Version="1">20925939</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Public Health Action. 2013 Dec 21;3(4):276-81</RefSource><PMID Version="1">26393046</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Pregnancy Childbirth. 2014 Sep 19;14:327</RefSource><PMID Version="1">25234069</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prev Med. 2007 Oct;45(4):247-51</RefSource><PMID Version="1">17950122</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Pediatr. 2012 Aug 07;12:116</RefSource><PMID Version="1">22871208</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Respir Care. 2015 Mar;60(3):437-45</RefSource><PMID Version="1">25389349</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2014 Jul 12;384(9938):189-205</RefSource><PMID Version="1">24853593</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 2005 Nov;10(11):1114-20</RefSource><PMID Version="1">16262736</PMID></CommentsCorrections></CommentsCorrectionsList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">South Sudan.</Keyword><Keyword MajorTopicYN="N">developing countries</Keyword><Keyword MajorTopicYN="N">neonatal mortality</Keyword><Keyword MajorTopicYN="N">newborn</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>10</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>10</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>10</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27789662</ArticleId><ArticleId IdType="pii">fmw071</ArticleId><ArticleId IdType="doi">10.1093/tropej/fmw071</ArticleId><ArticleId IdType="pmc">PMC5452431</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>France</li><li>Soudan du Sud</li><li>États-Unis</li></country><region><li>Île-de-France</li></region></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Thomson, Johanna" sort="Thomson, Johanna" uniqKey="Thomson J" first="Johanna" last="Thomson">Johanna Thomson</name></region></country><country name="Australie"><noRegion><name sortKey="Schaefer, Myrto" sort="Schaefer, Myrto" uniqKey="Schaefer M" first="Myrto" last="Schaefer">Myrto Schaefer</name></noRegion><name sortKey="Caminoa, Belen" sort="Caminoa, Belen" uniqKey="Caminoa B" first="Belen" last="Caminoa">Belen Caminoa</name></country><country name="Soudan du Sud"><noRegion><name sortKey="Kahindi, David" sort="Kahindi, David" uniqKey="Kahindi D" first="David" last="Kahindi">David Kahindi</name></noRegion></country><country name="États-Unis"><noRegion><name sortKey="Hurtado, Northan" sort="Hurtado, Northan" uniqKey="Hurtado N" first="Northan" last="Hurtado">Northan Hurtado</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A12 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000A12 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:27789662
|texte= Improved Neonatal Mortality at a District Hospital in Aweil, South Sudan.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:27789662" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |