Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium.
Identifieur interne : 000986 ( PubMed/Checkpoint ); précédent : 000985; suivant : 000987Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium.
Auteurs : Pilar Brito-Zer N [Espagne] ; Nihan Acar-Denizli [Turquie] ; Margit Zeher [Hongrie] ; Astrid Rasmussen [États-Unis] ; Raphaele Seror [France] ; Elke Theander [Suède] ; Xiaomei Li [République populaire de Chine] ; Chiara Baldini [Italie] ; Jacques-Eric Gottenberg [France] ; Debashish Danda [Inde] ; Luca Quartuccio [Italie] ; Roberta Priori [Italie] ; Gabriela Hernandez-Molina [Mexique] ; Aike A. Kruize [Pays-Bas] ; Valeria Valim [Brésil] ; Marika Kvarnstrom [Suède] ; Damien Sene [France] ; Roberto Gerli [Italie] ; Sonja Praprotnik [Slovénie] ; David Isenberg [Royaume-Uni] ; Roser Solans [Espagne] ; Maureen Rischmueller [Australie] ; Seung-Ki Kwok [Corée du Sud] ; Gunnel Nordmark [Suède] ; Yasunori Suzuki [Japon] ; Roberto Giacomelli [Italie] ; Valerie Devauchelle-Pensec [France] ; Michele Bombardieri [Royaume-Uni] ; Benedikt Hofauer [Allemagne] ; Hendrika Bootsma [Pays-Bas] ; Johan G. Brun [Norvège] ; Guadalupe Fraile [Espagne] ; Steven E. Carsons [États-Unis] ; Tamer A. Gheita [Égypte] ; Jacques Morel [France] ; Cristina Vollenveider [Argentine] ; Fabiola Atzeni [Italie] ; Soledad Retamozo [Argentine] ; Ildiko Fanny Horvath [Hongrie] ; Kathy Sivils [États-Unis] ; Thomas Mandl [Suède] ; Pulukool Sandhya [Inde] ; Salvatore De Vita [Italie] ; Jorge Sanchez-Guerrero [Mexique] ; Eefje Van Der Heijden [Pays-Bas] ; Virginia Fernandes Moça Trevisani [Brésil] ; Marie Wahren-Herlenius [Suède] ; Xavier Mariette [France] ; Manuel Ramos-Casals [Espagne]Source :
- Annals of the rheumatic diseases [ 1468-2060 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Afro-Américains (), Analyse spatiale, Anticorps antinucléaires (sang), Enregistrements, Femelle, Hispano-américain (), Humains, Maladies de l'oeil (étiologie), Mâle, Phénotype, Population d'origine asiatique (), Population d'origine européenne (), Prévalence, Sujet âgé, Syndrome de Gougerot-Sjögren (), Syndrome de Gougerot-Sjögren (diagnostic), Syndrome de Gougerot-Sjögren (ethnologie), Syndrome de Gougerot-Sjögren (sang), Études transversales.
- MESH :
- diagnostic : Syndrome de Gougerot-Sjögren.
- ethnologie : Syndrome de Gougerot-Sjögren.
- sang : Anticorps antinucléaires, Syndrome de Gougerot-Sjögren.
- étiologie : Maladies de l'oeil.
- Adulte, Adulte d'âge moyen, Afro-Américains, Analyse spatiale, Enregistrements, Femelle, Hispano-américain, Humains, Mâle, Phénotype, Population d'origine asiatique, Population d'origine européenne, Prévalence, Sujet âgé, Syndrome de Gougerot-Sjögren, Études transversales.
English descriptors
- KwdEn :
- Adult, African Americans (statistics & numerical data), Aged, Antibodies, Antinuclear (blood), Asian Continental Ancestry Group (statistics & numerical data), Cross-Sectional Studies, European Continental Ancestry Group (statistics & numerical data), Eye Diseases (etiology), Female, Hispanic Americans (statistics & numerical data), Humans, Male, Middle Aged, Phenotype, Prevalence, Registries, Sjogren's Syndrome (blood), Sjogren's Syndrome (complications), Sjogren's Syndrome (diagnosis), Sjogren's Syndrome (ethnology), Spatial Analysis.
- MESH :
- chemical , blood : Antibodies, Antinuclear.
- blood : Sjogren's Syndrome.
- complications : Sjogren's Syndrome.
- diagnosis : Sjogren's Syndrome.
- ethnology : Sjogren's Syndrome.
- etiology : Eye Diseases.
- statistics & numerical data : African Americans, Asian Continental Ancestry Group, European Continental Ancestry Group, Hispanic Americans.
- Adult, Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Phenotype, Prevalence, Registries, Spatial Analysis.
Abstract
To analyse the influence of geolocation and ethnicity on the clinical presentation of primary Sjögren's syndrome (SjS) at diagnosis.
DOI: 10.1136/annrheumdis-2016-209952
PubMed: 27899373
Affiliations:
- Allemagne, Argentine, Australie, Brésil, Corée du Sud, Espagne, France, Hongrie, Inde, Italie, Japon, Mexique, Norvège, Pays-Bas, Royaume-Uni, République populaire de Chine, Slovénie, Suède, Turquie, Égypte, États-Unis
- Alsace (région administrative), Angleterre, Anhui, Australie-Méridionale, Bavière, Catalogne, Communauté de Madrid, District de Haute-Bavière, East Middle Sweden, Grand Est, Grand Londres, Groningue (province), Languedoc-Roussillon, Latium, Lombardie, Occitanie (région administrative), Oklahoma, Région Bretagne, Région capitale de Séoul, Svealand, Toscane, Utrecht (province), État de New York, État de São Paulo, Île-de-France
- Barcelone, Brest, Groningue, Groningue (ville), Hefei, Londres, Madrid, Milan, Montpellier, Munich, Paris, Pise, Rome, Stockholm, Strasbourg, São Paulo, Séoul, Uppsala, Utrecht
- University College de Londres, Université d'Uppsala, Université de Groningue, Université de Londres, Université de Pise, Université de São Paulo
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sortKey="Rasmussen, Astrid" sort="Rasmussen, Astrid" uniqKey="Rasmussen A" first="Astrid" last="Rasmussen">Astrid Rasmussen</name><affiliation wicri:level="2"><nlm:affiliation>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma</wicri:regionArea><placeName><region type="state">Oklahoma</region></placeName></affiliation></author><author><name sortKey="Seror, Raphaele" sort="Seror, Raphaele" uniqKey="Seror R" first="Raphaele" last="Seror">Raphaele Seror</name><affiliation wicri:level="3"><nlm:affiliation>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Theander, Elke" sort="Theander, Elke" uniqKey="Theander E" first="Elke" last="Theander">Elke Theander</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, Malmö University Hospital, Lund University, Lund, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Rheumatology, Malmö University Hospital, Lund University, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Li, Xiaomei" sort="Li, Xiaomei" uniqKey="Li X" first="Xiaomei" last="Li">Xiaomei Li</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology and Immunology, Anhui Provincial Hospital, Hefei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Rheumatology and Immunology, Anhui Provincial Hospital, Hefei</wicri:regionArea><placeName><settlement type="city">Hefei</settlement><region type="province">Anhui</region></placeName></affiliation></author><author><name sortKey="Baldini, Chiara" sort="Baldini, Chiara" uniqKey="Baldini C" first="Chiara" last="Baldini">Chiara Baldini</name><affiliation wicri:level="4"><nlm:affiliation>Rheumatology Unit, University of Pisa, Pisa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Rheumatology Unit, University of Pisa, Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region><settlement type="city">Pise</settlement></placeName><orgName type="university">Université de Pise</orgName></affiliation></author><author><name sortKey="Gottenberg, Jacques Eric" sort="Gottenberg, Jacques Eric" uniqKey="Gottenberg J" first="Jacques-Eric" last="Gottenberg">Jacques-Eric Gottenberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Strasbourg University Hospital, Université de Strasbourg, CNRS, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Rheumatology, Strasbourg University Hospital, Université de Strasbourg, CNRS, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Danda, Debashish" sort="Danda, Debashish" uniqKey="Danda D" first="Debashish" last="Danda">Debashish Danda</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore</wicri:regionArea><wicri:noRegion>Vellore</wicri:noRegion></affiliation></author><author><name sortKey="Quartuccio, Luca" sort="Quartuccio, Luca" uniqKey="Quartuccio L" first="Luca" last="Quartuccio">Luca Quartuccio</name><affiliation wicri:level="1"><nlm:affiliation>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine</wicri:regionArea><wicri:noRegion>Udine</wicri:noRegion></affiliation></author><author><name sortKey="Priori, Roberta" sort="Priori, Roberta" uniqKey="Priori R" first="Roberta" last="Priori">Roberta Priori</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine and Medical Specialties, Rheumatology Clinic, Sapienza University of Rome, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Internal Medicine and Medical Specialties, Rheumatology Clinic, Sapienza University of Rome, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Hernandez Molina, Gabriela" sort="Hernandez Molina, Gabriela" uniqKey="Hernandez Molina G" first="Gabriela" last="Hernandez-Molina">Gabriela Hernandez-Molina</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City</wicri:regionArea><wicri:noRegion>Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City</wicri:noRegion></affiliation></author><author><name sortKey="Kruize, Aike A" sort="Kruize, Aike A" uniqKey="Kruize A" first="Aike A" last="Kruize">Aike A. Kruize</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Valim, Valeria" sort="Valim, Valeria" uniqKey="Valim V" first="Valeria" last="Valim">Valeria Valim</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Federal University of Espírito Santo, Vitória, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Medicine, Federal University of Espírito Santo, Vitória</wicri:regionArea><wicri:noRegion>Vitória</wicri:noRegion></affiliation></author><author><name sortKey="Kvarnstrom, Marika" sort="Kvarnstrom, Marika" uniqKey="Kvarnstrom M" first="Marika" last="Kvarnstrom">Marika Kvarnstrom</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Sene, Damien" sort="Sene, Damien" uniqKey="Sene D" first="Damien" last="Sene">Damien Sene</name><affiliation wicri:level="3"><nlm:affiliation>Département de Médecine Interne, Hôpital Lariboisière, Université Paris VII, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département de Médecine Interne, Hôpital Lariboisière, Université Paris VII, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Gerli, Roberto" sort="Gerli, Roberto" uniqKey="Gerli R" first="Roberto" last="Gerli">Roberto Gerli</name><affiliation wicri:level="1"><nlm:affiliation>Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Rheumatology Unit, Department of Medicine, University of Perugia, Perugia</wicri:regionArea><wicri:noRegion>Perugia</wicri:noRegion></affiliation></author><author><name sortKey="Praprotnik, Sonja" sort="Praprotnik, Sonja" uniqKey="Praprotnik S" first="Sonja" last="Praprotnik">Sonja Praprotnik</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia.</nlm:affiliation><country xml:lang="fr">Slovénie</country><wicri:regionArea>Department of Rheumatology, University Medical Centre, Ljubljana</wicri:regionArea><wicri:noRegion>Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Isenberg, David" sort="Isenberg, David" uniqKey="Isenberg D" first="David" last="Isenberg">David Isenberg</name><affiliation wicri:level="4"><nlm:affiliation>Division of Medicine, Centre for Rheumatology, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Medicine, Centre for Rheumatology, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Solans, Roser" sort="Solans, Roser" uniqKey="Solans R" first="Roser" last="Solans">Roser Solans</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Rischmueller, Maureen" sort="Rischmueller, Maureen" uniqKey="Rischmueller M" first="Maureen" last="Rischmueller">Maureen Rischmueller</name><affiliation wicri:level="2"><nlm:affiliation>Department of Rheumatology, The Queen Elizabeth Hospital, Discipline of Medicine University of Adelaide, South Australia.</nlm:affiliation><country>Australie</country><placeName><region type="state">Australie-Méridionale</region></placeName><wicri:cityArea>Department of Rheumatology, The Queen Elizabeth Hospital, Discipline of Medicine University of Adelaide</wicri:cityArea></affiliation></author><author><name sortKey="Kwok, Seung Ki" sort="Kwok, Seung Ki" uniqKey="Kwok S" first="Seung-Ki" last="Kwok">Seung-Ki Kwok</name><affiliation wicri:level="3"><nlm:affiliation>Division of Rheumatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Rheumatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Nordmark, Gunnel" sort="Nordmark, Gunnel" uniqKey="Nordmark G" first="Gunnel" last="Nordmark">Gunnel Nordmark</name><affiliation wicri:level="4"><nlm:affiliation>Rheumatology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Rheumatology, Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Suzuki, Yasunori" sort="Suzuki, Yasunori" uniqKey="Suzuki Y" first="Yasunori" last="Suzuki">Yasunori Suzuki</name><affiliation wicri:level="1"><nlm:affiliation>Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Ishikawa</wicri:regionArea><wicri:noRegion>Ishikawa</wicri:noRegion></affiliation></author><author><name sortKey="Giacomelli, Roberto" sort="Giacomelli, Roberto" uniqKey="Giacomelli R" first="Roberto" last="Giacomelli">Roberto Giacomelli</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Unit of Rheumatology, School of Medicine, University of l'Aquila, L'Aquila, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Clinical Unit of Rheumatology, School of Medicine, University of l'Aquila, L'Aquila</wicri:regionArea><wicri:noRegion>L'Aquila</wicri:noRegion></affiliation></author><author><name sortKey="Devauchelle Pensec, Valerie" sort="Devauchelle Pensec, Valerie" uniqKey="Devauchelle Pensec V" first="Valerie" last="Devauchelle-Pensec">Valerie Devauchelle-Pensec</name><affiliation wicri:level="3"><nlm:affiliation>Rheumatology Department, Brest University Hospital, Brest, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Rheumatology Department, Brest University Hospital, Brest</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Brest</settlement></placeName></affiliation></author><author><name sortKey="Bombardieri, Michele" sort="Bombardieri, Michele" uniqKey="Bombardieri M" first="Michele" last="Bombardieri">Michele Bombardieri</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Hofauer, Benedikt" sort="Hofauer, Benedikt" uniqKey="Hofauer B" first="Benedikt" last="Hofauer">Benedikt Hofauer</name><affiliation wicri:level="3"><nlm:affiliation>Otorhinolaryngology / Head and Neck Surgery, Technical University Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Otorhinolaryngology / Head and Neck Surgery, Technical University Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Bootsma, Hendrika" sort="Bootsma, Hendrika" uniqKey="Bootsma H" first="Hendrika" last="Bootsma">Hendrika Bootsma</name><affiliation wicri:level="4"><nlm:affiliation>Department of Rheumatology & Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rheumatology & Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Brun, Johan G" sort="Brun, Johan G" uniqKey="Brun J" first="Johan G" last="Brun">Johan G. Brun</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Science, University of Bergen; and Department of Rheumatology, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Science, University of Bergen; and Department of Rheumatology, Haukeland University Hospital, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Fraile, Guadalupe" sort="Fraile, Guadalupe" uniqKey="Fraile G" first="Guadalupe" last="Fraile">Guadalupe Fraile</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, Hospital Ramón y Cajal, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Internal Medicine, Hospital Ramón y Cajal, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Carsons, Steven E" sort="Carsons, Steven E" uniqKey="Carsons S" first="Steven E" last="Carsons">Steven E. Carsons</name><affiliation wicri:level="2"><nlm:affiliation>Division of Rheumatology, Allergy and Immunology Winthrop-University Hospital, Stony Brook University School of Medicine, Mineola, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Rheumatology, Allergy and Immunology Winthrop-University Hospital, Stony Brook University School of Medicine, Mineola, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Gheita, Tamer A" sort="Gheita, Tamer A" uniqKey="Gheita T" first="Tamer A" last="Gheita">Tamer A. Gheita</name><affiliation wicri:level="1"><nlm:affiliation>Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt.</nlm:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo</wicri:regionArea><wicri:noRegion>Cairo</wicri:noRegion></affiliation></author><author><name sortKey="Morel, Jacques" sort="Morel, Jacques" uniqKey="Morel J" first="Jacques" last="Morel">Jacques Morel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Teaching hospital and University of Montpellier, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Rheumatology, Teaching hospital and University of Montpellier, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Vollenveider, Cristina" sort="Vollenveider, Cristina" uniqKey="Vollenveider C" first="Cristina" last="Vollenveider">Cristina Vollenveider</name><affiliation wicri:level="1"><nlm:affiliation>German Hospital, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>German Hospital, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Atzeni, Fabiola" sort="Atzeni, Fabiola" uniqKey="Atzeni F" first="Fabiola" last="Atzeni">Fabiola Atzeni</name><affiliation wicri:level="3"><nlm:affiliation>IRCCS Galeazzi Orthopedic Institute, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IRCCS Galeazzi Orthopedic Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Retamozo, Soledad" sort="Retamozo, Soledad" uniqKey="Retamozo S" first="Soledad" last="Retamozo">Soledad Retamozo</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Privado Universitario de Córdoba, Institute University of Biomedical Sciences University of Córdoba (IUCBC), Cordoba, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Hospital Privado Universitario de Córdoba, Institute University of Biomedical Sciences University of Córdoba (IUCBC), Cordoba</wicri:regionArea><wicri:noRegion>Cordoba</wicri:noRegion></affiliation></author><author><name sortKey="Horvath, Ildiko Fanny" sort="Horvath, Ildiko Fanny" uniqKey="Horvath I" first="Ildiko Fanny" last="Horvath">Ildiko Fanny Horvath</name><affiliation wicri:level="1"><nlm:affiliation>Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen</wicri:regionArea><wicri:noRegion>Debrecen</wicri:noRegion></affiliation></author><author><name sortKey="Sivils, Kathy" sort="Sivils, Kathy" uniqKey="Sivils K" first="Kathy" last="Sivils">Kathy Sivils</name><affiliation wicri:level="2"><nlm:affiliation>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma</wicri:regionArea><placeName><region type="state">Oklahoma</region></placeName></affiliation></author><author><name sortKey="Mandl, Thomas" sort="Mandl, Thomas" uniqKey="Mandl T" first="Thomas" last="Mandl">Thomas Mandl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, Malmö University Hospital, Lund University, Lund, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Rheumatology, Malmö University Hospital, Lund University, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Sandhya, Pulukool" sort="Sandhya, Pulukool" uniqKey="Sandhya P" first="Pulukool" last="Sandhya">Pulukool Sandhya</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore</wicri:regionArea><wicri:noRegion>Vellore</wicri:noRegion></affiliation></author><author><name sortKey="De Vita, Salvatore" sort="De Vita, Salvatore" uniqKey="De Vita S" first="Salvatore" last="De Vita">Salvatore De Vita</name><affiliation wicri:level="1"><nlm:affiliation>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine</wicri:regionArea><wicri:noRegion>Udine</wicri:noRegion></affiliation></author><author><name sortKey="Sanchez Guerrero, Jorge" sort="Sanchez Guerrero, Jorge" uniqKey="Sanchez Guerrero J" first="Jorge" last="Sanchez-Guerrero">Jorge Sanchez-Guerrero</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City</wicri:regionArea><wicri:noRegion>Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City</wicri:noRegion></affiliation></author><author><name sortKey="Van Der Heijden, Eefje" sort="Van Der Heijden, Eefje" uniqKey="Van Der Heijden E" first="Eefje" last="Van Der Heijden">Eefje Van Der Heijden</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Trevisani, Virginia Fernandes Moca" sort="Trevisani, Virginia Fernandes Moca" uniqKey="Trevisani V" first="Virginia Fernandes Moça" last="Trevisani">Virginia Fernandes Moça Trevisani</name><affiliation wicri:level="4"><nlm:affiliation>Federal University of São Paulo, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Federal University of São Paulo, Sao Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Wahren Herlenius, Marie" sort="Wahren Herlenius, Marie" uniqKey="Wahren Herlenius M" first="Marie" last="Wahren-Herlenius">Marie Wahren-Herlenius</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Mariette, Xavier" sort="Mariette, Xavier" uniqKey="Mariette X" first="Xavier" last="Mariette">Xavier Mariette</name><affiliation wicri:level="3"><nlm:affiliation>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Ramos Casals, Manuel" sort="Ramos Casals, Manuel" uniqKey="Ramos Casals M" first="Manuel" last="Ramos-Casals">Manuel Ramos-Casals</name><affiliation wicri:level="3"><nlm:affiliation>Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:27899373</idno><idno type="pmid">27899373</idno><idno type="doi">10.1136/annrheumdis-2016-209952</idno><idno type="wicri:Area/PubMed/Corpus">000B62</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000B62</idno><idno type="wicri:Area/PubMed/Curation">000B59</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000B59</idno><idno type="wicri:Area/PubMed/Checkpoint">000B59</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000B59</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium.</title><author><name sortKey="Brito Zer N, Pilar" sort="Brito Zer N, Pilar" uniqKey="Brito Zer N P" first="Pilar" last="Brito-Zer N">Pilar Brito-Zer N</name><affiliation wicri:level="3"><nlm:affiliation>Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Acar Denizli, Nihan" sort="Acar Denizli, Nihan" uniqKey="Acar Denizli N" first="Nihan" last="Acar-Denizli">Nihan Acar-Denizli</name><affiliation wicri:level="1"><nlm:affiliation>Department of Statistics, Faculty of Science and Letters, Mimar Sinan Fine Arts University, Istanbul, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Statistics, Faculty of Science and Letters, Mimar Sinan Fine Arts University, Istanbul</wicri:regionArea><wicri:noRegion>Istanbul</wicri:noRegion></affiliation></author><author><name sortKey="Zeher, Margit" sort="Zeher, Margit" uniqKey="Zeher M" first="Margit" last="Zeher">Margit Zeher</name><affiliation wicri:level="1"><nlm:affiliation>Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen</wicri:regionArea><wicri:noRegion>Debrecen</wicri:noRegion></affiliation></author><author><name sortKey="Rasmussen, Astrid" sort="Rasmussen, Astrid" uniqKey="Rasmussen A" first="Astrid" last="Rasmussen">Astrid Rasmussen</name><affiliation wicri:level="2"><nlm:affiliation>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma</wicri:regionArea><placeName><region type="state">Oklahoma</region></placeName></affiliation></author><author><name sortKey="Seror, Raphaele" sort="Seror, Raphaele" uniqKey="Seror R" first="Raphaele" last="Seror">Raphaele Seror</name><affiliation wicri:level="3"><nlm:affiliation>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Theander, Elke" sort="Theander, Elke" uniqKey="Theander E" first="Elke" last="Theander">Elke Theander</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, Malmö University Hospital, Lund University, Lund, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Rheumatology, Malmö University Hospital, Lund University, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Li, Xiaomei" sort="Li, Xiaomei" uniqKey="Li X" first="Xiaomei" last="Li">Xiaomei Li</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology and Immunology, Anhui Provincial Hospital, Hefei, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Rheumatology and Immunology, Anhui Provincial Hospital, Hefei</wicri:regionArea><placeName><settlement type="city">Hefei</settlement><region type="province">Anhui</region></placeName></affiliation></author><author><name sortKey="Baldini, Chiara" sort="Baldini, Chiara" uniqKey="Baldini C" first="Chiara" last="Baldini">Chiara Baldini</name><affiliation wicri:level="4"><nlm:affiliation>Rheumatology Unit, University of Pisa, Pisa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Rheumatology Unit, University of Pisa, Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region><settlement type="city">Pise</settlement></placeName><orgName type="university">Université de Pise</orgName></affiliation></author><author><name sortKey="Gottenberg, Jacques Eric" sort="Gottenberg, Jacques Eric" uniqKey="Gottenberg J" first="Jacques-Eric" last="Gottenberg">Jacques-Eric Gottenberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Strasbourg University Hospital, Université de Strasbourg, CNRS, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Rheumatology, Strasbourg University Hospital, Université de Strasbourg, CNRS, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Danda, Debashish" sort="Danda, Debashish" uniqKey="Danda D" first="Debashish" last="Danda">Debashish Danda</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore</wicri:regionArea><wicri:noRegion>Vellore</wicri:noRegion></affiliation></author><author><name sortKey="Quartuccio, Luca" sort="Quartuccio, Luca" uniqKey="Quartuccio L" first="Luca" last="Quartuccio">Luca Quartuccio</name><affiliation wicri:level="1"><nlm:affiliation>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine</wicri:regionArea><wicri:noRegion>Udine</wicri:noRegion></affiliation></author><author><name sortKey="Priori, Roberta" sort="Priori, Roberta" uniqKey="Priori R" first="Roberta" last="Priori">Roberta Priori</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine and Medical Specialties, Rheumatology Clinic, Sapienza University of Rome, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Internal Medicine and Medical Specialties, Rheumatology Clinic, Sapienza University of Rome, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Hernandez Molina, Gabriela" sort="Hernandez Molina, Gabriela" uniqKey="Hernandez Molina G" first="Gabriela" last="Hernandez-Molina">Gabriela Hernandez-Molina</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City</wicri:regionArea><wicri:noRegion>Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City</wicri:noRegion></affiliation></author><author><name sortKey="Kruize, Aike A" sort="Kruize, Aike A" uniqKey="Kruize A" first="Aike A" last="Kruize">Aike A. Kruize</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Valim, Valeria" sort="Valim, Valeria" uniqKey="Valim V" first="Valeria" last="Valim">Valeria Valim</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Federal University of Espírito Santo, Vitória, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Medicine, Federal University of Espírito Santo, Vitória</wicri:regionArea><wicri:noRegion>Vitória</wicri:noRegion></affiliation></author><author><name sortKey="Kvarnstrom, Marika" sort="Kvarnstrom, Marika" uniqKey="Kvarnstrom M" first="Marika" last="Kvarnstrom">Marika Kvarnstrom</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Sene, Damien" sort="Sene, Damien" uniqKey="Sene D" first="Damien" last="Sene">Damien Sene</name><affiliation wicri:level="3"><nlm:affiliation>Département de Médecine Interne, Hôpital Lariboisière, Université Paris VII, Assistance Publique-Hôpitaux de Paris, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département de Médecine Interne, Hôpital Lariboisière, Université Paris VII, Assistance Publique-Hôpitaux de Paris, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Gerli, Roberto" sort="Gerli, Roberto" uniqKey="Gerli R" first="Roberto" last="Gerli">Roberto Gerli</name><affiliation wicri:level="1"><nlm:affiliation>Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Rheumatology Unit, Department of Medicine, University of Perugia, Perugia</wicri:regionArea><wicri:noRegion>Perugia</wicri:noRegion></affiliation></author><author><name sortKey="Praprotnik, Sonja" sort="Praprotnik, Sonja" uniqKey="Praprotnik S" first="Sonja" last="Praprotnik">Sonja Praprotnik</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia.</nlm:affiliation><country xml:lang="fr">Slovénie</country><wicri:regionArea>Department of Rheumatology, University Medical Centre, Ljubljana</wicri:regionArea><wicri:noRegion>Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Isenberg, David" sort="Isenberg, David" uniqKey="Isenberg D" first="David" last="Isenberg">David Isenberg</name><affiliation wicri:level="4"><nlm:affiliation>Division of Medicine, Centre for Rheumatology, University College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Medicine, Centre for Rheumatology, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Solans, Roser" sort="Solans, Roser" uniqKey="Solans R" first="Roser" last="Solans">Roser Solans</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Rischmueller, Maureen" sort="Rischmueller, Maureen" uniqKey="Rischmueller M" first="Maureen" last="Rischmueller">Maureen Rischmueller</name><affiliation wicri:level="2"><nlm:affiliation>Department of Rheumatology, The Queen Elizabeth Hospital, Discipline of Medicine University of Adelaide, South Australia.</nlm:affiliation><country>Australie</country><placeName><region type="state">Australie-Méridionale</region></placeName><wicri:cityArea>Department of Rheumatology, The Queen Elizabeth Hospital, Discipline of Medicine University of Adelaide</wicri:cityArea></affiliation></author><author><name sortKey="Kwok, Seung Ki" sort="Kwok, Seung Ki" uniqKey="Kwok S" first="Seung-Ki" last="Kwok">Seung-Ki Kwok</name><affiliation wicri:level="3"><nlm:affiliation>Division of Rheumatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Rheumatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Nordmark, Gunnel" sort="Nordmark, Gunnel" uniqKey="Nordmark G" first="Gunnel" last="Nordmark">Gunnel Nordmark</name><affiliation wicri:level="4"><nlm:affiliation>Rheumatology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Rheumatology, Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Suzuki, Yasunori" sort="Suzuki, Yasunori" uniqKey="Suzuki Y" first="Yasunori" last="Suzuki">Yasunori Suzuki</name><affiliation wicri:level="1"><nlm:affiliation>Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Ishikawa</wicri:regionArea><wicri:noRegion>Ishikawa</wicri:noRegion></affiliation></author><author><name sortKey="Giacomelli, Roberto" sort="Giacomelli, Roberto" uniqKey="Giacomelli R" first="Roberto" last="Giacomelli">Roberto Giacomelli</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Unit of Rheumatology, School of Medicine, University of l'Aquila, L'Aquila, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Clinical Unit of Rheumatology, School of Medicine, University of l'Aquila, L'Aquila</wicri:regionArea><wicri:noRegion>L'Aquila</wicri:noRegion></affiliation></author><author><name sortKey="Devauchelle Pensec, Valerie" sort="Devauchelle Pensec, Valerie" uniqKey="Devauchelle Pensec V" first="Valerie" last="Devauchelle-Pensec">Valerie Devauchelle-Pensec</name><affiliation wicri:level="3"><nlm:affiliation>Rheumatology Department, Brest University Hospital, Brest, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Rheumatology Department, Brest University Hospital, Brest</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Brest</settlement></placeName></affiliation></author><author><name sortKey="Bombardieri, Michele" sort="Bombardieri, Michele" uniqKey="Bombardieri M" first="Michele" last="Bombardieri">Michele Bombardieri</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Hofauer, Benedikt" sort="Hofauer, Benedikt" uniqKey="Hofauer B" first="Benedikt" last="Hofauer">Benedikt Hofauer</name><affiliation wicri:level="3"><nlm:affiliation>Otorhinolaryngology / Head and Neck Surgery, Technical University Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Otorhinolaryngology / Head and Neck Surgery, Technical University Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Bootsma, Hendrika" sort="Bootsma, Hendrika" uniqKey="Bootsma H" first="Hendrika" last="Bootsma">Hendrika Bootsma</name><affiliation wicri:level="4"><nlm:affiliation>Department of Rheumatology & Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rheumatology & Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Brun, Johan G" sort="Brun, Johan G" uniqKey="Brun J" first="Johan G" last="Brun">Johan G. Brun</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Science, University of Bergen; and Department of Rheumatology, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Science, University of Bergen; and Department of Rheumatology, Haukeland University Hospital, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Fraile, Guadalupe" sort="Fraile, Guadalupe" uniqKey="Fraile G" first="Guadalupe" last="Fraile">Guadalupe Fraile</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, Hospital Ramón y Cajal, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Internal Medicine, Hospital Ramón y Cajal, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Carsons, Steven E" sort="Carsons, Steven E" uniqKey="Carsons S" first="Steven E" last="Carsons">Steven E. Carsons</name><affiliation wicri:level="2"><nlm:affiliation>Division of Rheumatology, Allergy and Immunology Winthrop-University Hospital, Stony Brook University School of Medicine, Mineola, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Rheumatology, Allergy and Immunology Winthrop-University Hospital, Stony Brook University School of Medicine, Mineola, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Gheita, Tamer A" sort="Gheita, Tamer A" uniqKey="Gheita T" first="Tamer A" last="Gheita">Tamer A. Gheita</name><affiliation wicri:level="1"><nlm:affiliation>Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt.</nlm:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo</wicri:regionArea><wicri:noRegion>Cairo</wicri:noRegion></affiliation></author><author><name sortKey="Morel, Jacques" sort="Morel, Jacques" uniqKey="Morel J" first="Jacques" last="Morel">Jacques Morel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Teaching hospital and University of Montpellier, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Rheumatology, Teaching hospital and University of Montpellier, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Vollenveider, Cristina" sort="Vollenveider, Cristina" uniqKey="Vollenveider C" first="Cristina" last="Vollenveider">Cristina Vollenveider</name><affiliation wicri:level="1"><nlm:affiliation>German Hospital, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>German Hospital, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Atzeni, Fabiola" sort="Atzeni, Fabiola" uniqKey="Atzeni F" first="Fabiola" last="Atzeni">Fabiola Atzeni</name><affiliation wicri:level="3"><nlm:affiliation>IRCCS Galeazzi Orthopedic Institute, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IRCCS Galeazzi Orthopedic Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Retamozo, Soledad" sort="Retamozo, Soledad" uniqKey="Retamozo S" first="Soledad" last="Retamozo">Soledad Retamozo</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Privado Universitario de Córdoba, Institute University of Biomedical Sciences University of Córdoba (IUCBC), Cordoba, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Hospital Privado Universitario de Córdoba, Institute University of Biomedical Sciences University of Córdoba (IUCBC), Cordoba</wicri:regionArea><wicri:noRegion>Cordoba</wicri:noRegion></affiliation></author><author><name sortKey="Horvath, Ildiko Fanny" sort="Horvath, Ildiko Fanny" uniqKey="Horvath I" first="Ildiko Fanny" last="Horvath">Ildiko Fanny Horvath</name><affiliation wicri:level="1"><nlm:affiliation>Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen</wicri:regionArea><wicri:noRegion>Debrecen</wicri:noRegion></affiliation></author><author><name sortKey="Sivils, Kathy" sort="Sivils, Kathy" uniqKey="Sivils K" first="Kathy" last="Sivils">Kathy Sivils</name><affiliation wicri:level="2"><nlm:affiliation>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma</wicri:regionArea><placeName><region type="state">Oklahoma</region></placeName></affiliation></author><author><name sortKey="Mandl, Thomas" sort="Mandl, Thomas" uniqKey="Mandl T" first="Thomas" last="Mandl">Thomas Mandl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, Malmö University Hospital, Lund University, Lund, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Rheumatology, Malmö University Hospital, Lund University, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Sandhya, Pulukool" sort="Sandhya, Pulukool" uniqKey="Sandhya P" first="Pulukool" last="Sandhya">Pulukool Sandhya</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore</wicri:regionArea><wicri:noRegion>Vellore</wicri:noRegion></affiliation></author><author><name sortKey="De Vita, Salvatore" sort="De Vita, Salvatore" uniqKey="De Vita S" first="Salvatore" last="De Vita">Salvatore De Vita</name><affiliation wicri:level="1"><nlm:affiliation>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine</wicri:regionArea><wicri:noRegion>Udine</wicri:noRegion></affiliation></author><author><name sortKey="Sanchez Guerrero, Jorge" sort="Sanchez Guerrero, Jorge" uniqKey="Sanchez Guerrero J" first="Jorge" last="Sanchez-Guerrero">Jorge Sanchez-Guerrero</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City</wicri:regionArea><wicri:noRegion>Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City</wicri:noRegion></affiliation></author><author><name sortKey="Van Der Heijden, Eefje" sort="Van Der Heijden, Eefje" uniqKey="Van Der Heijden E" first="Eefje" last="Van Der Heijden">Eefje Van Der Heijden</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Trevisani, Virginia Fernandes Moca" sort="Trevisani, Virginia Fernandes Moca" uniqKey="Trevisani V" first="Virginia Fernandes Moça" last="Trevisani">Virginia Fernandes Moça Trevisani</name><affiliation wicri:level="4"><nlm:affiliation>Federal University of São Paulo, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Federal University of São Paulo, Sao Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Wahren Herlenius, Marie" sort="Wahren Herlenius, Marie" uniqKey="Wahren Herlenius M" first="Marie" last="Wahren-Herlenius">Marie Wahren-Herlenius</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Mariette, Xavier" sort="Mariette, Xavier" uniqKey="Mariette X" first="Xavier" last="Mariette">Xavier Mariette</name><affiliation wicri:level="3"><nlm:affiliation>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Ramos Casals, Manuel" sort="Ramos Casals, Manuel" uniqKey="Ramos Casals M" first="Manuel" last="Ramos-Casals">Manuel Ramos-Casals</name><affiliation wicri:level="3"><nlm:affiliation>Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author></analytic><series><title level="j">Annals of the rheumatic diseases</title><idno type="eISSN">1468-2060</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>African Americans (statistics & numerical data)</term><term>Aged</term><term>Antibodies, Antinuclear (blood)</term><term>Asian Continental Ancestry Group (statistics & numerical data)</term><term>Cross-Sectional Studies</term><term>European Continental Ancestry Group (statistics & numerical data)</term><term>Eye Diseases (etiology)</term><term>Female</term><term>Hispanic Americans (statistics & numerical data)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Phenotype</term><term>Prevalence</term><term>Registries</term><term>Sjogren's Syndrome (blood)</term><term>Sjogren's Syndrome (complications)</term><term>Sjogren's Syndrome (diagnosis)</term><term>Sjogren's Syndrome (ethnology)</term><term>Spatial Analysis</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Afro-Américains ()</term><term>Analyse spatiale</term><term>Anticorps antinucléaires (sang)</term><term>Enregistrements</term><term>Femelle</term><term>Hispano-américain ()</term><term>Humains</term><term>Maladies de l'oeil (étiologie)</term><term>Mâle</term><term>Phénotype</term><term>Population d'origine asiatique ()</term><term>Population d'origine européenne ()</term><term>Prévalence</term><term>Sujet âgé</term><term>Syndrome de Gougerot-Sjögren ()</term><term>Syndrome de Gougerot-Sjögren (diagnostic)</term><term>Syndrome de Gougerot-Sjögren (ethnologie)</term><term>Syndrome de Gougerot-Sjögren (sang)</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Antinuclear</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Sjogren's Syndrome</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Sjogren's Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Sjogren's Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Syndrome de Gougerot-Sjögren</term></keywords><keywords scheme="MESH" qualifier="ethnologie" xml:lang="fr"><term>Syndrome de Gougerot-Sjögren</term></keywords><keywords scheme="MESH" qualifier="ethnology" xml:lang="en"><term>Sjogren's Syndrome</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Eye Diseases</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antinucléaires</term><term>Syndrome de Gougerot-Sjögren</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>African Americans</term><term>Asian Continental Ancestry Group</term><term>European Continental Ancestry Group</term><term>Hispanic Americans</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Maladies de l'oeil</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Cross-Sectional Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Phenotype</term><term>Prevalence</term><term>Registries</term><term>Spatial Analysis</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Afro-Américains</term><term>Analyse spatiale</term><term>Enregistrements</term><term>Femelle</term><term>Hispano-américain</term><term>Humains</term><term>Mâle</term><term>Phénotype</term><term>Population d'origine asiatique</term><term>Population d'origine européenne</term><term>Prévalence</term><term>Sujet âgé</term><term>Syndrome de Gougerot-Sjögren</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To analyse the influence of geolocation and ethnicity on the clinical presentation of primary Sjögren's syndrome (SjS) at diagnosis.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27899373</PMID><DateCreated><Year>2016</Year><Month>11</Month><Day>30</Day></DateCreated><DateCompleted><Year>2017</Year><Month>08</Month><Day>14</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1468-2060</ISSN><JournalIssue CitedMedium="Internet"><Volume>76</Volume><Issue>6</Issue><PubDate><Year>2017</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Annals of the rheumatic diseases</Title><ISOAbbreviation>Ann. Rheum. Dis.</ISOAbbreviation></Journal><ArticleTitle>Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium.</ArticleTitle><Pagination><MedlinePgn>1042-1050</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1136/annrheumdis-2016-209952</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To analyse the influence of geolocation and ethnicity on the clinical presentation of primary Sjögren's syndrome (SjS) at diagnosis.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The Big Data Sjögren Project Consortium is an international, multicentre registry designed in 2014. By January 2016, 20 centres from five continents were participating. Multivariable logistic regression analyses were performed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">We included 7748 women (93%) and 562 men (7%), with a mean age at diagnosis of primary SjS of 53 years. Ethnicity data were available for 7884 patients (95%): 6174 patients (78%) were white, 1066 patients (14%) were Asian, 393 patients (5%) were Hispanic, 104 patients (1%) were black/African-American and 147 patients (2%) were of other ethnicities. SjS was diagnosed a mean of 7 years earlier in black/African-American compared with white patients; the female-to-male ratio was highest in Asian patients (27:1) and lowest in black/African-American patients (7:1); the prevalence of sicca symptoms was lowest in Asian patients; a higher frequency of positive salivary biopsy was found in Hispanic and white patients. A north-south gradient was found with respect to a lower frequency of ocular involvement in northern countries for dry eyes and abnormal ocular tests in Europe (OR 0.46 and 0.44, respectively) and Asia (OR 0.18 and 0.49, respectively) compared with southern countries. Higher frequencies of antinuclear antibodies (ANAs) were reported in northern countries in America (OR=1.48) and Asia (OR=3.80) while, in Europe, northern countries had lowest frequencies of ANAs (OR=0.67) and Ro/La (OR=0.69).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This study provides the first evidence of a strong influence of geolocation and ethnicity on the phenotype of primary SjS at diagnosis.</AbstractText><CopyrightInformation>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Brito-Zerón</LastName><ForeName>Pilar</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Acar-Denizli</LastName><ForeName>Nihan</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Statistics, Faculty of Science and Letters, Mimar Sinan Fine Arts University, Istanbul, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zeher</LastName><ForeName>Margit</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rasmussen</LastName><ForeName>Astrid</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Seror</LastName><ForeName>Raphaele</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Theander</LastName><ForeName>Elke</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Rheumatology, Malmö University Hospital, Lund University, Lund, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Xiaomei</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Department of Rheumatology and Immunology, Anhui Provincial Hospital, Hefei, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baldini</LastName><ForeName>Chiara</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Rheumatology Unit, University of Pisa, Pisa, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gottenberg</LastName><ForeName>Jacques-Eric</ForeName><Initials>JE</Initials><AffiliationInfo><Affiliation>Department of Rheumatology, Strasbourg University Hospital, Université de Strasbourg, CNRS, Strasbourg, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Danda</LastName><ForeName>Debashish</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Quartuccio</LastName><ForeName>Luca</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", Udine, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Priori</LastName><ForeName>Roberta</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine and Medical Specialties, Rheumatology Clinic, Sapienza University of Rome, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hernandez-Molina</LastName><ForeName>Gabriela</ForeName><Initials>G</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-7958-0391</Identifier><AffiliationInfo><Affiliation>Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. 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México City, Mexico.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Heijden</LastName><ForeName>Eefje</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Trevisani</LastName><ForeName>Virginia Fernandes Moça</ForeName><Initials>VFM</Initials><AffiliationInfo><Affiliation>Federal University of São Paulo, Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wahren-Herlenius</LastName><ForeName>Marie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mariette</LastName><ForeName>Xavier</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM U1184, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ramos-Casals</LastName><ForeName>Manuel</ForeName><Initials>M</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-5709-6734</Identifier><AffiliationInfo><Affiliation>Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic, Barcelona, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medicine, University of Barcelona, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>EULAR-SS Task Force Big Data Consortium</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>MR/N003063/1</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>11</Month><Day>29</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Ann Rheum Dis</MedlineTA><NlmUniqueID>0372355</NlmUniqueID><ISSNLinking>0003-4967</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000974">Antibodies, Antinuclear</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001741" MajorTopicYN="N">African Americans</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000974" MajorTopicYN="N">Antibodies, Antinuclear</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D044466" MajorTopicYN="N">Asian Continental Ancestry Group</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D044465" MajorTopicYN="N">European Continental Ancestry Group</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005128" MajorTopicYN="N">Eye Diseases</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006630" MajorTopicYN="N">Hispanic Americans</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010641" MajorTopicYN="N">Phenotype</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012042" MajorTopicYN="Y">Registries</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012859" MajorTopicYN="N">Sjogren's Syndrome</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000208" MajorTopicYN="Y">ethnology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D062206" MajorTopicYN="N">Spatial Analysis</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Autoimmune Diseases</Keyword><Keyword MajorTopicYN="N">Autoimmunity</Keyword><Keyword MajorTopicYN="N">Epidemiology</Keyword><Keyword MajorTopicYN="N">Sjøgren's Syndrome</Keyword></KeywordList><CoiStatement>Competing interests: None declared.</CoiStatement><InvestigatorList><Investigator ValidYN="Y"><LastName>Morcillo</LastName><ForeName>C</ForeName><Initials>C</Initials></Investigator><Investigator ValidYN="Y"><LastName>Brito-Zerón</LastName><ForeName>P</ForeName><Initials>P</Initials></Investigator><Investigator ValidYN="Y"><LastName>García-Sánchez</LastName><ForeName>I</ForeName><Initials>I</Initials></Investigator><Investigator ValidYN="Y"><LastName>Gheitasi</LastName><ForeName>H</ForeName><Initials>H</Initials></Investigator><Investigator ValidYN="Y"><LastName>Bové</LastName><ForeName>A</ForeName><Initials>A</Initials></Investigator><Investigator ValidYN="Y"><LastName>Ramos-Casals</LastName><ForeName>M</ForeName><Initials>M</Initials></Investigator><Investigator ValidYN="Y"><LastName>Horvath</LastName><ForeName>Ildike-Fanny</ForeName><Initials>IF</Initials></Investigator><Investigator ValidYN="Y"><LastName>Sivils</LastName><ForeName>K</ForeName><Initials>K</Initials></Investigator><Investigator 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PubStatus="medline"><Year>2017</Year><Month>8</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>12</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27899373</ArticleId><ArticleId IdType="pii">annrheumdis-2016-209952</ArticleId><ArticleId IdType="doi">10.1136/annrheumdis-2016-209952</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Argentine</li><li>Australie</li><li>Brésil</li><li>Corée du Sud</li><li>Espagne</li><li>France</li><li>Hongrie</li><li>Inde</li><li>Italie</li><li>Japon</li><li>Mexique</li><li>Norvège</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>Slovénie</li><li>Suède</li><li>Turquie</li><li>Égypte</li><li>États-Unis</li></country><region><li>Alsace (région 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d'Uppsala</li><li>Université de Groningue</li><li>Université de Londres</li><li>Université de Pise</li><li>Université de São Paulo</li></orgName></list><tree><country name="Espagne"><region name="Catalogne"><name sortKey="Brito Zer N, Pilar" sort="Brito Zer N, Pilar" uniqKey="Brito Zer N P" first="Pilar" last="Brito-Zer N">Pilar Brito-Zer N</name></region><name sortKey="Fraile, Guadalupe" sort="Fraile, Guadalupe" uniqKey="Fraile G" first="Guadalupe" last="Fraile">Guadalupe Fraile</name><name sortKey="Ramos Casals, Manuel" sort="Ramos Casals, Manuel" uniqKey="Ramos Casals M" first="Manuel" last="Ramos-Casals">Manuel Ramos-Casals</name><name sortKey="Solans, Roser" sort="Solans, Roser" uniqKey="Solans R" first="Roser" last="Solans">Roser Solans</name></country><country name="Turquie"><noRegion><name sortKey="Acar Denizli, Nihan" sort="Acar Denizli, Nihan" uniqKey="Acar Denizli N" first="Nihan" last="Acar-Denizli">Nihan Acar-Denizli</name></noRegion></country><country name="Hongrie"><noRegion><name sortKey="Zeher, Margit" sort="Zeher, Margit" uniqKey="Zeher M" first="Margit" last="Zeher">Margit Zeher</name></noRegion><name sortKey="Horvath, Ildiko Fanny" sort="Horvath, Ildiko Fanny" uniqKey="Horvath I" first="Ildiko Fanny" last="Horvath">Ildiko Fanny Horvath</name></country><country name="États-Unis"><region name="Oklahoma"><name sortKey="Rasmussen, Astrid" sort="Rasmussen, Astrid" uniqKey="Rasmussen A" first="Astrid" last="Rasmussen">Astrid Rasmussen</name></region><name sortKey="Carsons, Steven E" sort="Carsons, Steven E" uniqKey="Carsons S" first="Steven E" last="Carsons">Steven E. 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Kruize</name></region><name sortKey="Bootsma, Hendrika" sort="Bootsma, Hendrika" uniqKey="Bootsma H" first="Hendrika" last="Bootsma">Hendrika Bootsma</name><name sortKey="Van Der Heijden, Eefje" sort="Van Der Heijden, Eefje" uniqKey="Van Der Heijden E" first="Eefje" last="Van Der Heijden">Eefje Van Der Heijden</name></country><country name="Brésil"><noRegion><name sortKey="Valim, Valeria" sort="Valim, Valeria" uniqKey="Valim V" first="Valeria" last="Valim">Valeria Valim</name></noRegion><name sortKey="Trevisani, Virginia Fernandes Moca" sort="Trevisani, Virginia Fernandes Moca" uniqKey="Trevisani V" first="Virginia Fernandes Moça" last="Trevisani">Virginia Fernandes Moça Trevisani</name></country><country name="Slovénie"><noRegion><name sortKey="Praprotnik, Sonja" sort="Praprotnik, Sonja" uniqKey="Praprotnik S" first="Sonja" last="Praprotnik">Sonja Praprotnik</name></noRegion></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Isenberg, David" sort="Isenberg, David" uniqKey="Isenberg D" first="David" last="Isenberg">David Isenberg</name></region><name sortKey="Bombardieri, Michele" sort="Bombardieri, Michele" uniqKey="Bombardieri M" first="Michele" last="Bombardieri">Michele Bombardieri</name></country><country name="Australie"><region name="Australie-Méridionale"><name sortKey="Rischmueller, Maureen" sort="Rischmueller, Maureen" uniqKey="Rischmueller M" first="Maureen" last="Rischmueller">Maureen Rischmueller</name></region></country><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Kwok, Seung Ki" sort="Kwok, Seung Ki" uniqKey="Kwok S" first="Seung-Ki" last="Kwok">Seung-Ki Kwok</name></region></country><country name="Japon"><noRegion><name sortKey="Suzuki, Yasunori" sort="Suzuki, Yasunori" uniqKey="Suzuki Y" first="Yasunori" last="Suzuki">Yasunori Suzuki</name></noRegion></country><country name="Allemagne"><region name="Bavière"><name sortKey="Hofauer, Benedikt" sort="Hofauer, Benedikt" uniqKey="Hofauer B" first="Benedikt" last="Hofauer">Benedikt Hofauer</name></region></country><country name="Norvège"><noRegion><name sortKey="Brun, Johan G" sort="Brun, Johan G" uniqKey="Brun J" first="Johan G" last="Brun">Johan G. Brun</name></noRegion></country><country name="Égypte"><noRegion><name sortKey="Gheita, Tamer A" sort="Gheita, Tamer A" uniqKey="Gheita T" first="Tamer A" last="Gheita">Tamer A. Gheita</name></noRegion></country><country name="Argentine"><noRegion><name sortKey="Vollenveider, Cristina" sort="Vollenveider, Cristina" uniqKey="Vollenveider C" first="Cristina" last="Vollenveider">Cristina Vollenveider</name></noRegion><name sortKey="Retamozo, Soledad" sort="Retamozo, Soledad" uniqKey="Retamozo S" first="Soledad" last="Retamozo">Soledad Retamozo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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