Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome.
Identifieur interne : 000371 ( PubMed/Checkpoint ); précédent : 000370; suivant : 000372Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome.
Auteurs : Nicolas Nin [Espagne] ; Alfonso Muriel [Espagne] ; Oscar Pe Uelas [Espagne] ; Laurent Brochard [Canada] ; José Angel Lorente [Espagne] ; Niall D. Ferguson [Canada] ; Konstantinos Raymondos [Allemagne] ; Fernando Ríos [Argentine] ; Damian A. Violi [Argentine] ; Arnaud W. Thille [France] ; Marco González [Colombie] ; Asisclo J. Villagomez [Mexique] ; Javier Hurtado [Uruguay] ; Andrew R. Davies [Australie] ; Bin Du [République populaire de Chine] ; Salvatore M. Maggiore [Italie] ; Luis Soto [Chili] ; Gabriel D'Empaire [Venezuela] ; Dimitrios Matamis [Grèce] ; Fekri Abroug [Tunisie] ; Rui P. Moreno [Portugal] ; Marco Antonio Soares [Brésil] ; Yaseen Arabi [Arabie saoudite] ; Freddy Sandi ; Manuel Jibaja [Équateur] ; Pravin Amin [Inde] ; Younsuck Koh [Corée du Sud] ; Michael A. Kuiper [Pays-Bas] ; Hans-Henrik Bülow [Danemark] ; Amine Ali Zeggwagh [Maroc] ; Antonio Anzueto [États-Unis] ; Jacob I. Sznajder [États-Unis] ; Andres Esteban [Espagne]Source :
- Intensive care medicine [ 1432-1238 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Facteurs temps, Femelle, Humains, Hypercapnie (), Hypercapnie (mortalité), Hypercapnie (étiologie), Indice de gravité médicale, Indice de gravité simplifié, Modèles logistiques, Mâle, Score de propension, Sujet âgé, Syndrome de détresse respiratoire de l'adulte (), Syndrome de détresse respiratoire de l'adulte (mortalité), Unités de soins intensifs, Ventilation artificielle (effets indésirables), Études prospectives.
- MESH :
- effets indésirables : Ventilation artificielle.
- mortalité : Hypercapnie, Syndrome de détresse respiratoire de l'adulte.
- étiologie : Hypercapnie.
- Adulte, Adulte d'âge moyen, Facteurs temps, Femelle, Humains, Hypercapnie, Indice de gravité médicale, Indice de gravité simplifié, Modèles logistiques, Mâle, Score de propension, Sujet âgé, Syndrome de détresse respiratoire de l'adulte, Unités de soins intensifs, Études prospectives.
English descriptors
- KwdEn :
- Adult, Aged, Female, Humans, Hypercapnia (etiology), Hypercapnia (mortality), Hypercapnia (therapy), Intensive Care Units, Logistic Models, Male, Middle Aged, Propensity Score, Prospective Studies, Respiration, Artificial (adverse effects), Respiratory Distress Syndrome, Adult (complications), Respiratory Distress Syndrome, Adult (mortality), Respiratory Distress Syndrome, Adult (therapy), Severity of Illness Index, Simplified Acute Physiology Score, Time Factors.
- MESH :
- adverse effects : Respiration, Artificial.
- complications : Respiratory Distress Syndrome, Adult.
- etiology : Hypercapnia.
- mortality : Hypercapnia, Respiratory Distress Syndrome, Adult.
- therapy : Hypercapnia, Respiratory Distress Syndrome, Adult.
- Adult, Aged, Female, Humans, Intensive Care Units, Logistic Models, Male, Middle Aged, Propensity Score, Prospective Studies, Severity of Illness Index, Simplified Acute Physiology Score, Time Factors.
Abstract
To analyze the relationship between hypercapnia developing within the first 48 h after the start of mechanical ventilation and outcome in patients with acute respiratory distress syndrome (ARDS).
DOI: 10.1007/s00134-016-4611-1
PubMed: 28108768
Affiliations:
- Allemagne, Arabie saoudite, Argentine, Australie, Brésil, Canada, Chili, Colombie, Corée du Sud, Danemark, Espagne, France, Grèce, Inde, Italie, Maroc, Mexique, Pays-Bas, Portugal, République populaire de Chine, Tunisie, Uruguay, Venezuela, Équateur, États-Unis
- Communauté de Madrid, Illinois, Latium, Minas Gerais, Nouvelle-Aquitaine, Ontario, Poitou-Charentes, Rabat-Salé-Kénitra, Région capitale de Séoul, Texas, Victoria (État)
- Belo Horizonte, Madrid, Melbourne, Poitiers, Pékin, Rabat, Rome, Séoul, Toronto
- Université de Toronto
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:28108768Le document en format XML
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Moreno</name><affiliation wicri:level="1"><nlm:affiliation>UCINC, Hospital de Sao José, Centro Hospitalar de Lisboa Central, E.P.E., Lisbon, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>UCINC, Hospital de Sao José, Centro Hospitalar de Lisboa Central, E.P.E., Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Soares, Marco Antonio" sort="Soares, Marco Antonio" uniqKey="Soares M" first="Marco Antonio" last="Soares">Marco Antonio Soares</name><affiliation wicri:level="3"><nlm:affiliation>Hospital Universitario Sao José, Belo Horizonte, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Hospital Universitario Sao José, Belo Horizonte</wicri:regionArea><placeName><settlement type="city">Belo Horizonte</settlement><region type="state">Minas Gerais</region></placeName></affiliation></author><author><name sortKey="Arabi, Yaseen" sort="Arabi, Yaseen" uniqKey="Arabi Y" first="Yaseen" last="Arabi">Yaseen Arabi</name><affiliation wicri:level="1"><nlm:affiliation>King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>King Saud Bin Abdulaziz University for Health Sciences, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Sandi, Freddy" sort="Sandi, Freddy" uniqKey="Sandi F" first="Freddy" last="Sandi">Freddy Sandi</name><affiliation><nlm:affiliation>Hospital Obrero No. 1, La Paz, Bolivia.</nlm:affiliation><wicri:noCountry code="subField">Bolivia</wicri:noCountry></affiliation></author><author><name sortKey="Jibaja, Manuel" sort="Jibaja, Manuel" uniqKey="Jibaja M" first="Manuel" last="Jibaja">Manuel Jibaja</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Eugenio Espejo, Quito, Ecuador.</nlm:affiliation><country xml:lang="fr">Équateur</country><wicri:regionArea>Hospital Eugenio Espejo, Quito</wicri:regionArea><wicri:noRegion>Quito</wicri:noRegion></affiliation></author><author><name sortKey="Amin, Pravin" sort="Amin, Pravin" uniqKey="Amin P" first="Pravin" last="Amin">Pravin Amin</name><affiliation wicri:level="1"><nlm:affiliation>Bombay Hospital Institute of Medical Sciences, Mumbai, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Bombay Hospital Institute of Medical Sciences, Mumbai</wicri:regionArea><wicri:noRegion>Mumbai</wicri:noRegion></affiliation></author><author><name sortKey="Koh, Younsuck" sort="Koh, Younsuck" uniqKey="Koh Y" first="Younsuck" last="Koh">Younsuck Koh</name><affiliation wicri:level="3"><nlm:affiliation>Asan Medical Center, University of Ulsan, Seoul, Republic of Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Asan Medical Center, University of Ulsan, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kuiper, Michael A" sort="Kuiper, Michael A" uniqKey="Kuiper M" first="Michael A" last="Kuiper">Michael A. Kuiper</name><affiliation wicri:level="1"><nlm:affiliation>Medical Center Leeuwarden (MCL), Leeuwarden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Medical Center Leeuwarden (MCL), Leeuwarden</wicri:regionArea><wicri:noRegion>Leeuwarden</wicri:noRegion></affiliation></author><author><name sortKey="Bulow, Hans Henrik" sort="Bulow, Hans Henrik" uniqKey="Bulow H" first="Hans-Henrik" last="Bülow">Hans-Henrik Bülow</name><affiliation wicri:level="1"><nlm:affiliation>Holbaek Hospital, University of Copenhagen, Copenhagen, Region Zealand, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Holbaek Hospital, University of Copenhagen, Copenhagen, Region Zealand</wicri:regionArea><wicri:noRegion>Region Zealand</wicri:noRegion></affiliation></author><author><name sortKey="Zeggwagh, Amine Ali" sort="Zeggwagh, Amine Ali" uniqKey="Zeggwagh A" first="Amine Ali" last="Zeggwagh">Amine Ali Zeggwagh</name><affiliation wicri:level="3"><nlm:affiliation>Hospital Ibn Sina, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Hospital Ibn Sina, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Anzueto, Antonio" sort="Anzueto, Antonio" uniqKey="Anzueto A" first="Antonio" last="Anzueto">Antonio Anzueto</name><affiliation wicri:level="2"><nlm:affiliation>South Texas Veterans Health Care System and University of Texas Health Science Center, San Antonio, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>South Texas Veterans Health Care System and University of Texas Health Science Center, San Antonio, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Sznajder, Jacob I" sort="Sznajder, Jacob I" uniqKey="Sznajder J" first="Jacob I" last="Sznajder">Jacob I. Sznajder</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Esteban, Andres" sort="Esteban, Andres" uniqKey="Esteban A" first="Andres" last="Esteban">Andres Esteban</name><affiliation wicri:level="3"><nlm:affiliation>CIBER Enfermedades Respiratorias, Madrid, Spain. aesteban@ucigetafe.com.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Enfermedades Respiratorias, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28108768</idno><idno type="pmid">28108768</idno><idno type="doi">10.1007/s00134-016-4611-1</idno><idno type="wicri:Area/PubMed/Corpus">001148</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001148</idno><idno type="wicri:Area/PubMed/Curation">001145</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001145</idno><idno type="wicri:Area/PubMed/Checkpoint">001145</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001145</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome.</title><author><name sortKey="Nin, Nicolas" sort="Nin, Nicolas" uniqKey="Nin N" first="Nicolas" last="Nin">Nicolas Nin</name><affiliation wicri:level="3"><nlm:affiliation>Hospital de Torrejón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital de Torrejón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Muriel, Alfonso" sort="Muriel, Alfonso" uniqKey="Muriel A" first="Alfonso" last="Muriel">Alfonso Muriel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Biostatistics, Hospital Ramón Y Cajal, IRICYS and CIBERESP, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Clinical Biostatistics, Hospital Ramón Y Cajal, IRICYS and CIBERESP, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Pe Uelas, Oscar" sort="Pe Uelas, Oscar" uniqKey="Pe Uelas O" first="Oscar" last="Pe Uelas">Oscar Pe Uelas</name><affiliation wicri:level="3"><nlm:affiliation>CIBER Enfermedades Respiratorias, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Enfermedades Respiratorias, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Brochard, Laurent" sort="Brochard, Laurent" uniqKey="Brochard L" first="Laurent" last="Brochard">Laurent Brochard</name><affiliation wicri:level="1"><nlm:affiliation>Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Lorente, Jose Angel" sort="Lorente, Jose Angel" uniqKey="Lorente J" first="José Angel" last="Lorente">José Angel Lorente</name><affiliation wicri:level="3"><nlm:affiliation>CIBER Enfermedades Respiratorias, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Enfermedades Respiratorias, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Ferguson, Niall D" sort="Ferguson, Niall D" uniqKey="Ferguson N" first="Niall D" last="Ferguson">Niall D. Ferguson</name><affiliation wicri:level="4"><nlm:affiliation>Interdepartmental Division of Critical Care Medicine and Departments of Medicine and Physiology, University of Toronto, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Interdepartmental Division of Critical Care Medicine and Departments of Medicine and Physiology, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Raymondos, Konstantinos" sort="Raymondos, Konstantinos" uniqKey="Raymondos K" first="Konstantinos" last="Raymondos">Konstantinos Raymondos</name><affiliation wicri:level="1"><nlm:affiliation>Medizinische Hochschule Hannover, Hanover, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medizinische Hochschule Hannover, Hanover</wicri:regionArea><wicri:noRegion>Hanover</wicri:noRegion><wicri:noRegion>Hanover</wicri:noRegion><wicri:noRegion>Hanover</wicri:noRegion></affiliation></author><author><name sortKey="Rios, Fernando" sort="Rios, Fernando" uniqKey="Rios F" first="Fernando" last="Ríos">Fernando Ríos</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Nacional Alejandro Posadas, Buenos Aires, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Hospital Nacional Alejandro Posadas, Buenos Aires</wicri:regionArea><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Violi, Damian A" sort="Violi, Damian A" uniqKey="Violi D" first="Damian A" last="Violi">Damian A. Violi</name><affiliation wicri:level="1"><nlm:affiliation>Hospital HIGA Guemes, Haedo, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Hospital HIGA Guemes, Haedo</wicri:regionArea><wicri:noRegion>Haedo</wicri:noRegion></affiliation></author><author><name sortKey="Thille, Arnaud W" sort="Thille, Arnaud W" uniqKey="Thille A" first="Arnaud W" last="Thille">Arnaud W. Thille</name><affiliation wicri:level="3"><nlm:affiliation>University Hospital of Poitiers, Poitiers, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Hospital of Poitiers, Poitiers</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Poitou-Charentes</region><settlement type="city">Poitiers</settlement></placeName></affiliation></author><author><name sortKey="Gonzalez, Marco" sort="Gonzalez, Marco" uniqKey="Gonzalez M" first="Marco" last="González">Marco González</name><affiliation wicri:level="1"><nlm:affiliation>Clínica Medellín and Universidad Pontificia Bolivariana, Medellín, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Clínica Medellín and Universidad Pontificia Bolivariana, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Villagomez, Asisclo J" sort="Villagomez, Asisclo J" uniqKey="Villagomez A" first="Asisclo J" last="Villagomez">Asisclo J. Villagomez</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Regional 1° de Octubre, ISSSTE, Mexico City, Mexico.</nlm:affiliation><country xml:lang="fr">Mexique</country><wicri:regionArea>Hospital Regional 1° de Octubre, ISSSTE, Mexico City</wicri:regionArea><wicri:noRegion>Mexico City</wicri:noRegion></affiliation></author><author><name sortKey="Hurtado, Javier" sort="Hurtado, Javier" uniqKey="Hurtado J" first="Javier" last="Hurtado">Javier Hurtado</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Español, Montevideo, Uruguay.</nlm:affiliation><country xml:lang="fr">Uruguay</country><wicri:regionArea>Hospital Español, Montevideo</wicri:regionArea><wicri:noRegion>Montevideo</wicri:noRegion></affiliation></author><author><name sortKey="Davies, Andrew R" sort="Davies, Andrew R" uniqKey="Davies A" first="Andrew R" last="Davies">Andrew R. Davies</name><affiliation wicri:level="3"><nlm:affiliation>Alfred Hospital and Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Alfred Hospital and Monash University, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Du, Bin" sort="Du, Bin" uniqKey="Du B" first="Bin" last="Du">Bin Du</name><affiliation wicri:level="3"><nlm:affiliation>Peking Union Medical College Hospital, Beijing, People's Republic of China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Peking Union Medical College Hospital, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Maggiore, Salvatore M" sort="Maggiore, Salvatore M" uniqKey="Maggiore S" first="Salvatore M" last="Maggiore">Salvatore M. Maggiore</name><affiliation wicri:level="3"><nlm:affiliation>Policlinico Agostino Gemelli, Università Cattolica Del Sacro Cuore, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Policlinico Agostino Gemelli, Università Cattolica Del Sacro Cuore, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Soto, Luis" sort="Soto, Luis" uniqKey="Soto L" first="Luis" last="Soto">Luis Soto</name><affiliation wicri:level="1"><nlm:affiliation>Instituto Nacional del Tórax de Santiago, Santiago, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Instituto Nacional del Tórax de Santiago, Santiago</wicri:regionArea><wicri:noRegion>Santiago</wicri:noRegion></affiliation></author><author><name sortKey="D Empaire, Gabriel" sort="D Empaire, Gabriel" uniqKey="D Empaire G" first="Gabriel" last="D'Empaire">Gabriel D'Empaire</name><affiliation wicri:level="1"><nlm:affiliation>Hospital de Clínicas de Caracas, Caracas, Venezuela.</nlm:affiliation><country xml:lang="fr">Venezuela</country><wicri:regionArea>Hospital de Clínicas de Caracas, Caracas</wicri:regionArea><wicri:noRegion>Caracas</wicri:noRegion></affiliation></author><author><name sortKey="Matamis, Dimitrios" sort="Matamis, Dimitrios" uniqKey="Matamis D" first="Dimitrios" last="Matamis">Dimitrios Matamis</name><affiliation wicri:level="1"><nlm:affiliation>Papageorgiou Hospital, Thessaloniki, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Papageorgiou Hospital, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author><author><name sortKey="Abroug, Fekri" sort="Abroug, Fekri" uniqKey="Abroug F" first="Fekri" last="Abroug">Fekri Abroug</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Fattouma Bourguina, Monastir, Tunisia.</nlm:affiliation><country xml:lang="fr">Tunisie</country><wicri:regionArea>Hospital Fattouma Bourguina, Monastir</wicri:regionArea><wicri:noRegion>Monastir</wicri:noRegion></affiliation></author><author><name sortKey="Moreno, Rui P" sort="Moreno, Rui P" uniqKey="Moreno R" first="Rui P" last="Moreno">Rui P. Moreno</name><affiliation wicri:level="1"><nlm:affiliation>UCINC, Hospital de Sao José, Centro Hospitalar de Lisboa Central, E.P.E., Lisbon, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>UCINC, Hospital de Sao José, Centro Hospitalar de Lisboa Central, E.P.E., Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Soares, Marco Antonio" sort="Soares, Marco Antonio" uniqKey="Soares M" first="Marco Antonio" last="Soares">Marco Antonio Soares</name><affiliation wicri:level="3"><nlm:affiliation>Hospital Universitario Sao José, Belo Horizonte, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Hospital Universitario Sao José, Belo Horizonte</wicri:regionArea><placeName><settlement type="city">Belo Horizonte</settlement><region type="state">Minas Gerais</region></placeName></affiliation></author><author><name sortKey="Arabi, Yaseen" sort="Arabi, Yaseen" uniqKey="Arabi Y" first="Yaseen" last="Arabi">Yaseen Arabi</name><affiliation wicri:level="1"><nlm:affiliation>King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>King Saud Bin Abdulaziz University for Health Sciences, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Sandi, Freddy" sort="Sandi, Freddy" uniqKey="Sandi F" first="Freddy" last="Sandi">Freddy Sandi</name><affiliation><nlm:affiliation>Hospital Obrero No. 1, La Paz, Bolivia.</nlm:affiliation><wicri:noCountry code="subField">Bolivia</wicri:noCountry></affiliation></author><author><name sortKey="Jibaja, Manuel" sort="Jibaja, Manuel" uniqKey="Jibaja M" first="Manuel" last="Jibaja">Manuel Jibaja</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Eugenio Espejo, Quito, Ecuador.</nlm:affiliation><country xml:lang="fr">Équateur</country><wicri:regionArea>Hospital Eugenio Espejo, Quito</wicri:regionArea><wicri:noRegion>Quito</wicri:noRegion></affiliation></author><author><name sortKey="Amin, Pravin" sort="Amin, Pravin" uniqKey="Amin P" first="Pravin" last="Amin">Pravin Amin</name><affiliation wicri:level="1"><nlm:affiliation>Bombay Hospital Institute of Medical Sciences, Mumbai, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Bombay Hospital Institute of Medical Sciences, Mumbai</wicri:regionArea><wicri:noRegion>Mumbai</wicri:noRegion></affiliation></author><author><name sortKey="Koh, Younsuck" sort="Koh, Younsuck" uniqKey="Koh Y" first="Younsuck" last="Koh">Younsuck Koh</name><affiliation wicri:level="3"><nlm:affiliation>Asan Medical Center, University of Ulsan, Seoul, Republic of Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Asan Medical Center, University of Ulsan, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kuiper, Michael A" sort="Kuiper, Michael A" uniqKey="Kuiper M" first="Michael A" last="Kuiper">Michael A. Kuiper</name><affiliation wicri:level="1"><nlm:affiliation>Medical Center Leeuwarden (MCL), Leeuwarden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Medical Center Leeuwarden (MCL), Leeuwarden</wicri:regionArea><wicri:noRegion>Leeuwarden</wicri:noRegion></affiliation></author><author><name sortKey="Bulow, Hans Henrik" sort="Bulow, Hans Henrik" uniqKey="Bulow H" first="Hans-Henrik" last="Bülow">Hans-Henrik Bülow</name><affiliation wicri:level="1"><nlm:affiliation>Holbaek Hospital, University of Copenhagen, Copenhagen, Region Zealand, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Holbaek Hospital, University of Copenhagen, Copenhagen, Region Zealand</wicri:regionArea><wicri:noRegion>Region Zealand</wicri:noRegion></affiliation></author><author><name sortKey="Zeggwagh, Amine Ali" sort="Zeggwagh, Amine Ali" uniqKey="Zeggwagh A" first="Amine Ali" last="Zeggwagh">Amine Ali Zeggwagh</name><affiliation wicri:level="3"><nlm:affiliation>Hospital Ibn Sina, Rabat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Hospital Ibn Sina, Rabat</wicri:regionArea><placeName><settlement type="city">Rabat</settlement><region nuts="2">Rabat-Salé-Kénitra</region></placeName></affiliation></author><author><name sortKey="Anzueto, Antonio" sort="Anzueto, Antonio" uniqKey="Anzueto A" first="Antonio" last="Anzueto">Antonio Anzueto</name><affiliation wicri:level="2"><nlm:affiliation>South Texas Veterans Health Care System and University of Texas Health Science Center, San Antonio, TX, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>South Texas Veterans Health Care System and University of Texas Health Science Center, San Antonio, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Sznajder, Jacob I" sort="Sznajder, Jacob I" uniqKey="Sznajder J" first="Jacob I" last="Sznajder">Jacob I. Sznajder</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Esteban, Andres" sort="Esteban, Andres" uniqKey="Esteban A" first="Andres" last="Esteban">Andres Esteban</name><affiliation wicri:level="3"><nlm:affiliation>CIBER Enfermedades Respiratorias, Madrid, Spain. aesteban@ucigetafe.com.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Enfermedades Respiratorias, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author></analytic><series><title level="j">Intensive care medicine</title><idno type="eISSN">1432-1238</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Hypercapnia (etiology)</term><term>Hypercapnia (mortality)</term><term>Hypercapnia (therapy)</term><term>Intensive Care Units</term><term>Logistic Models</term><term>Male</term><term>Middle Aged</term><term>Propensity Score</term><term>Prospective Studies</term><term>Respiration, Artificial (adverse effects)</term><term>Respiratory Distress Syndrome, Adult (complications)</term><term>Respiratory Distress Syndrome, Adult (mortality)</term><term>Respiratory Distress Syndrome, Adult (therapy)</term><term>Severity of Illness Index</term><term>Simplified Acute Physiology Score</term><term>Time Factors</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Hypercapnie ()</term><term>Hypercapnie (mortalité)</term><term>Hypercapnie (étiologie)</term><term>Indice de gravité médicale</term><term>Indice de gravité simplifié</term><term>Modèles logistiques</term><term>Mâle</term><term>Score de propension</term><term>Sujet âgé</term><term>Syndrome de détresse respiratoire de l'adulte ()</term><term>Syndrome de détresse respiratoire de l'adulte (mortalité)</term><term>Unités de soins intensifs</term><term>Ventilation artificielle (effets indésirables)</term><term>Études prospectives</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Respiration, Artificial</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Respiratory Distress Syndrome, Adult</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Ventilation artificielle</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Hypercapnia</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Hypercapnia</term><term>Respiratory Distress Syndrome, Adult</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Hypercapnie</term><term>Syndrome de détresse respiratoire de l'adulte</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Hypercapnia</term><term>Respiratory Distress Syndrome, Adult</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Hypercapnie</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Intensive Care Units</term><term>Logistic Models</term><term>Male</term><term>Middle Aged</term><term>Propensity Score</term><term>Prospective Studies</term><term>Severity of Illness Index</term><term>Simplified Acute Physiology Score</term><term>Time Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Hypercapnie</term><term>Indice de gravité médicale</term><term>Indice de gravité simplifié</term><term>Modèles logistiques</term><term>Mâle</term><term>Score de propension</term><term>Sujet âgé</term><term>Syndrome de détresse respiratoire de l'adulte</term><term>Unités de soins intensifs</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To analyze the relationship between hypercapnia developing within the first 48 h after the start of mechanical ventilation and outcome in patients with acute respiratory distress syndrome (ARDS).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28108768</PMID><DateCreated><Year>2017</Year><Month>01</Month><Day>21</Day></DateCreated><DateCompleted><Year>2017</Year><Month>11</Month><Day>07</Day></DateCompleted><DateRevised><Year>2017</Year><Month>11</Month><Day>07</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1432-1238</ISSN><JournalIssue CitedMedium="Internet"><Volume>43</Volume><Issue>2</Issue><PubDate><Year>2017</Year><Month>Feb</Month></PubDate></JournalIssue><Title>Intensive care medicine</Title><ISOAbbreviation>Intensive Care Med</ISOAbbreviation></Journal><ArticleTitle>Severe hypercapnia and outcome of mechanically ventilated patients with moderate or severe acute respiratory distress syndrome.</ArticleTitle><Pagination><MedlinePgn>200-208</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00134-016-4611-1</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To analyze the relationship between hypercapnia developing within the first 48 h after the start of mechanical ventilation and outcome in patients with acute respiratory distress syndrome (ARDS).</AbstractText><AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">We performed a secondary analysis of three prospective non-interventional cohort studies focusing on ARDS patients from 927 intensive care units (ICUs) in 40 countries. These patients received mechanical ventilation for more than 12 h during 1-month periods in 1998, 2004, and 2010. We used multivariable logistic regression and a propensity score analysis to examine the association between hypercapnia and ICU mortality.</AbstractText><AbstractText Label="MAIN OUTCOMES" NlmCategory="RESULTS">We included 1899 patients with ARDS in this study. The relationship between maximum PaCO2 in the first 48 h and mortality suggests higher mortality at or above PaCO2 of ≥50 mmHg. Patients with severe hypercapnia (PaCO2 ≥50 mmHg) had higher complication rates, more organ failures, and worse outcomes. After adjusting for age, SAPS II score, respiratory rate, positive end-expiratory pressure, PaO2/FiO2 ratio, driving pressure, pressure/volume limitation strategy (PLS), corrected minute ventilation, and presence of acidosis, severe hypercapnia was associated with increased risk of ICU mortality [odds ratio (OR) 1.93, 95% confidence interval (CI) 1.32 to 2.81; p = 0.001]. In patients with severe hypercapnia matched for all other variables, ventilation with PLS was associated with higher ICU mortality (OR 1.58, CI 95% 1.04-2.41; p = 0.032).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Severe hypercapnia appears to be independently associated with higher ICU mortality in patients with ARDS.</AbstractText><AbstractText Label="TRIAL REGISTRATION" NlmCategory="BACKGROUND">Clinicaltrials.gov identifier, NCT01093482.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nin</LastName><ForeName>Nicolas</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Hospital de Torrejón, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Hospital Español, Montevideo, Uruguay.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Muriel</LastName><ForeName>Alfonso</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Clinical Biostatistics, Hospital Ramón Y Cajal, IRICYS and CIBERESP, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peñuelas</LastName><ForeName>Oscar</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>CIBER Enfermedades Respiratorias, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Hospital Universitario de Getafe, Carretera de Toledo, Km 12,500, 28905, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brochard</LastName><ForeName>Laurent</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lorente</LastName><ForeName>José Angel</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>CIBER Enfermedades Respiratorias, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Hospital Universitario de Getafe, Carretera de Toledo, Km 12,500, 28905, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ferguson</LastName><ForeName>Niall D</ForeName><Initials>ND</Initials><AffiliationInfo><Affiliation>Interdepartmental Division of Critical Care Medicine and Departments of Medicine and Physiology, University of Toronto, Toronto, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raymondos</LastName><ForeName>Konstantinos</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Medizinische Hochschule Hannover, Hanover, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ríos</LastName><ForeName>Fernando</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Hospital Nacional Alejandro Posadas, Buenos Aires, Argentina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Violi</LastName><ForeName>Damian A</ForeName><Initials>DA</Initials><AffiliationInfo><Affiliation>Hospital HIGA Guemes, Haedo, Argentina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thille</LastName><ForeName>Arnaud W</ForeName><Initials>AW</Initials><AffiliationInfo><Affiliation>University Hospital of Poitiers, Poitiers, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>González</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Clínica Medellín and Universidad Pontificia Bolivariana, Medellín, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Villagomez</LastName><ForeName>Asisclo J</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>Hospital Regional 1° de Octubre, ISSSTE, Mexico City, Mexico.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hurtado</LastName><ForeName>Javier</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Hospital Español, Montevideo, Uruguay.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davies</LastName><ForeName>Andrew R</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>Alfred Hospital and Monash University, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Du</LastName><ForeName>Bin</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Peking Union Medical College Hospital, Beijing, People's Republic of China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maggiore</LastName><ForeName>Salvatore M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Policlinico Agostino Gemelli, Università Cattolica Del Sacro Cuore, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soto</LastName><ForeName>Luis</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Instituto Nacional del Tórax de Santiago, Santiago, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>D'Empaire</LastName><ForeName>Gabriel</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Hospital de Clínicas de Caracas, Caracas, Venezuela.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Matamis</LastName><ForeName>Dimitrios</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Papageorgiou Hospital, Thessaloniki, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abroug</LastName><ForeName>Fekri</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Hospital Fattouma Bourguina, Monastir, Tunisia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moreno</LastName><ForeName>Rui P</ForeName><Initials>RP</Initials><AffiliationInfo><Affiliation>UCINC, Hospital de Sao José, Centro Hospitalar de Lisboa Central, E.P.E., Lisbon, Portugal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soares</LastName><ForeName>Marco Antonio</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Hospital Universitario Sao José, Belo Horizonte, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arabi</LastName><ForeName>Yaseen</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sandi</LastName><ForeName>Freddy</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Hospital Obrero No. 1, La Paz, Bolivia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jibaja</LastName><ForeName>Manuel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Hospital Eugenio Espejo, Quito, Ecuador.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Amin</LastName><ForeName>Pravin</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Bombay Hospital Institute of Medical Sciences, Mumbai, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koh</LastName><ForeName>Younsuck</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Asan Medical Center, University of Ulsan, Seoul, Republic of Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kuiper</LastName><ForeName>Michael A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Medical Center Leeuwarden (MCL), Leeuwarden, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bülow</LastName><ForeName>Hans-Henrik</ForeName><Initials>HH</Initials><AffiliationInfo><Affiliation>Holbaek Hospital, University of Copenhagen, Copenhagen, Region Zealand, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zeggwagh</LastName><ForeName>Amine Ali</ForeName><Initials>AA</Initials><AffiliationInfo><Affiliation>Hospital Ibn Sina, Rabat, Morocco.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anzueto</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>South Texas Veterans Health Care System and University of Texas Health Science Center, San Antonio, TX, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sznajder</LastName><ForeName>Jacob I</ForeName><Initials>JI</Initials><AffiliationInfo><Affiliation>Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Esteban</LastName><ForeName>Andres</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>CIBER Enfermedades Respiratorias, Madrid, Spain. aesteban@ucigetafe.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Hospital Universitario de Getafe, Carretera de Toledo, Km 12,500, 28905, Madrid, Spain. aesteban@ucigetafe.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>VENTILA Group</CollectiveName></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>ClinicalTrials.gov</DataBankName><AccessionNumberList><AccessionNumber>NCT01093482</AccessionNumber></AccessionNumberList></DataBank></DataBankList><GrantList CompleteYN="Y"><Grant><GrantID>P01 HL071643</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 HL048129</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 HL085534</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R37 HL048129</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>01</Month><Day>20</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Intensive Care Med</MedlineTA><NlmUniqueID>7704851</NlmUniqueID><ISSNLinking>0342-4642</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>J Thorac Dis. 2017 Jun;9(6):1420-1425</RefSource><PMID Version="1">28740647</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Respir Crit Care Med. 2002 Aug 1;166(3):403-8</RefSource><PMID Version="1">12153979</PMID></CommentsCorrections><CommentsCorrections 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Version="1">2200314</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Respir Crit Care Med. 2005 Jun 15;171(12):1371-7</RefSource><PMID Version="1">15695495</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006935" MajorTopicYN="N">Hypercapnia</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007362" MajorTopicYN="Y">Intensive Care Units</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016015" MajorTopicYN="N">Logistic Models</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D057216" MajorTopicYN="N">Propensity Score</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012121" MajorTopicYN="N">Respiration, Artificial</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012128" MajorTopicYN="N">Respiratory Distress Syndrome, Adult</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000072878" MajorTopicYN="N">Simplified Acute Physiology Score</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Acute respiratory distress syndrome</Keyword><Keyword MajorTopicYN="N">Hypercapnia</Keyword><Keyword MajorTopicYN="N">ICU mortality</Keyword><Keyword MajorTopicYN="N">Mechanical ventilation</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>07</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>10</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>1</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>11</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>1</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28108768</ArticleId><ArticleId IdType="doi">10.1007/s00134-016-4611-1</ArticleId><ArticleId IdType="pii">10.1007/s00134-016-4611-1</ArticleId><ArticleId IdType="pmc">PMC5630225</ArticleId><ArticleId IdType="mid">NIHMS907568</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Arabie saoudite</li><li>Argentine</li><li>Australie</li><li>Brésil</li><li>Canada</li><li>Chili</li><li>Colombie</li><li>Corée du Sud</li><li>Danemark</li><li>Espagne</li><li>France</li><li>Grèce</li><li>Inde</li><li>Italie</li><li>Maroc</li><li>Mexique</li><li>Pays-Bas</li><li>Portugal</li><li>République populaire de Chine</li><li>Tunisie</li><li>Uruguay</li><li>Venezuela</li><li>Équateur</li><li>États-Unis</li></country><region><li>Communauté de Madrid</li><li>Illinois</li><li>Latium</li><li>Minas Gerais</li><li>Nouvelle-Aquitaine</li><li>Ontario</li><li>Poitou-Charentes</li><li>Rabat-Salé-Kénitra</li><li>Région capitale de Séoul</li><li>Texas</li><li>Victoria (État)</li></region><settlement><li>Belo Horizonte</li><li>Madrid</li><li>Melbourne</li><li>Poitiers</li><li>Pékin</li><li>Rabat</li><li>Rome</li><li>Séoul</li><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Sandi, Freddy" sort="Sandi, Freddy" uniqKey="Sandi F" first="Freddy" last="Sandi">Freddy Sandi</name></noCountry><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Nin, Nicolas" sort="Nin, Nicolas" uniqKey="Nin N" first="Nicolas" last="Nin">Nicolas Nin</name></region><name sortKey="Esteban, Andres" sort="Esteban, Andres" uniqKey="Esteban A" first="Andres" last="Esteban">Andres Esteban</name><name sortKey="Lorente, Jose Angel" sort="Lorente, Jose Angel" uniqKey="Lorente J" first="José Angel" last="Lorente">José Angel Lorente</name><name sortKey="Muriel, Alfonso" sort="Muriel, Alfonso" uniqKey="Muriel A" first="Alfonso" last="Muriel">Alfonso Muriel</name><name sortKey="Pe Uelas, Oscar" sort="Pe Uelas, Oscar" uniqKey="Pe Uelas O" first="Oscar" last="Pe Uelas">Oscar Pe Uelas</name></country><country name="Canada"><noRegion><name sortKey="Brochard, Laurent" sort="Brochard, Laurent" uniqKey="Brochard L" first="Laurent" last="Brochard">Laurent Brochard</name></noRegion><name sortKey="Ferguson, Niall D" sort="Ferguson, Niall D" uniqKey="Ferguson N" first="Niall D" last="Ferguson">Niall D. Ferguson</name></country><country name="Allemagne"><noRegion><name sortKey="Raymondos, Konstantinos" sort="Raymondos, Konstantinos" uniqKey="Raymondos K" first="Konstantinos" last="Raymondos">Konstantinos Raymondos</name></noRegion></country><country name="Argentine"><noRegion><name sortKey="Rios, Fernando" sort="Rios, Fernando" uniqKey="Rios F" first="Fernando" last="Ríos">Fernando Ríos</name></noRegion><name sortKey="Violi, Damian A" sort="Violi, Damian A" uniqKey="Violi D" first="Damian A" last="Violi">Damian A. Violi</name></country><country name="France"><region name="Nouvelle-Aquitaine"><name sortKey="Thille, Arnaud W" sort="Thille, Arnaud W" uniqKey="Thille A" first="Arnaud W" last="Thille">Arnaud W. Thille</name></region></country><country name="Colombie"><noRegion><name sortKey="Gonzalez, Marco" sort="Gonzalez, Marco" uniqKey="Gonzalez M" first="Marco" last="González">Marco González</name></noRegion></country><country name="Mexique"><noRegion><name sortKey="Villagomez, Asisclo J" sort="Villagomez, Asisclo J" uniqKey="Villagomez A" first="Asisclo J" last="Villagomez">Asisclo J. Villagomez</name></noRegion></country><country name="Uruguay"><noRegion><name sortKey="Hurtado, Javier" sort="Hurtado, Javier" uniqKey="Hurtado J" first="Javier" last="Hurtado">Javier Hurtado</name></noRegion></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Davies, Andrew R" sort="Davies, Andrew R" uniqKey="Davies A" first="Andrew R" last="Davies">Andrew R. Davies</name></region></country><country name="République populaire de Chine"><noRegion><name sortKey="Du, Bin" sort="Du, Bin" uniqKey="Du B" first="Bin" last="Du">Bin Du</name></noRegion></country><country name="Italie"><region name="Latium"><name sortKey="Maggiore, Salvatore M" sort="Maggiore, Salvatore M" uniqKey="Maggiore S" first="Salvatore M" last="Maggiore">Salvatore M. 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Moreno</name></noRegion></country><country name="Brésil"><region name="Minas Gerais"><name sortKey="Soares, Marco Antonio" sort="Soares, Marco Antonio" uniqKey="Soares M" first="Marco Antonio" last="Soares">Marco Antonio Soares</name></region></country><country name="Arabie saoudite"><noRegion><name sortKey="Arabi, Yaseen" sort="Arabi, Yaseen" uniqKey="Arabi Y" first="Yaseen" last="Arabi">Yaseen Arabi</name></noRegion></country><country name="Équateur"><noRegion><name sortKey="Jibaja, Manuel" sort="Jibaja, Manuel" uniqKey="Jibaja M" first="Manuel" last="Jibaja">Manuel Jibaja</name></noRegion></country><country name="Inde"><noRegion><name sortKey="Amin, Pravin" sort="Amin, Pravin" uniqKey="Amin P" first="Pravin" last="Amin">Pravin Amin</name></noRegion></country><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Koh, Younsuck" sort="Koh, Younsuck" uniqKey="Koh Y" first="Younsuck" last="Koh">Younsuck Koh</name></region></country><country name="Pays-Bas"><noRegion><name sortKey="Kuiper, Michael A" sort="Kuiper, Michael A" uniqKey="Kuiper M" first="Michael A" last="Kuiper">Michael A. Kuiper</name></noRegion></country><country name="Danemark"><noRegion><name sortKey="Bulow, Hans Henrik" sort="Bulow, Hans Henrik" uniqKey="Bulow H" first="Hans-Henrik" last="Bülow">Hans-Henrik Bülow</name></noRegion></country><country name="Maroc"><region name="Rabat-Salé-Kénitra"><name sortKey="Zeggwagh, Amine Ali" sort="Zeggwagh, Amine Ali" uniqKey="Zeggwagh A" first="Amine Ali" last="Zeggwagh">Amine Ali Zeggwagh</name></region></country><country name="États-Unis"><region name="Texas"><name sortKey="Anzueto, Antonio" sort="Anzueto, Antonio" uniqKey="Anzueto A" first="Antonio" last="Anzueto">Antonio Anzueto</name></region><name sortKey="Sznajder, Jacob I" sort="Sznajder, Jacob I" uniqKey="Sznajder J" first="Jacob I" last="Sznajder">Jacob I. Sznajder</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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