The evolution of lung transplantation for cystic fibrosis: A 2017 update.
Identifieur interne : 000195 ( PubMed/Checkpoint ); précédent : 000194; suivant : 000196The evolution of lung transplantation for cystic fibrosis: A 2017 update.
Auteurs : Gregory Snell [Australie] ; Anna Reed [Royaume-Uni] ; Marc Stern [France] ; Denis Hadjiliadis [États-Unis]Source :
- Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [ 1873-5010 ] ; 2017.
Abstract
Lung transplantation (LTx) is an established therapy for patients with end-stage cystic fibrosis (CF). Indeed, CF is the commonest indication for those aged<50years of age needing LTx. CF LTx is associated with a 45% 10year survival - according to the world's largest registry. It is important all otherwise suitable CF patients with severe lung disease have a timely referral for discussion and consideration of the possibility of LTx. LTx discussions must carefully consider colonisation or infection with Burkholderia cenocepacia, Mycobacterium abscessus and Scediosporium - as good LTx outcomes cannot be guaranteed. A bridge to LTx with extra-corporeal lung support is a realistic option, but remains a relative contraindication to LTx. Improvements in LTx matching technology and post-operative management are steadily improving overall long-term outcomes, although chronic allograft rejection remains problematic. Expert multidisciplinary life-long post-LTx care remains the key to success.
DOI: 10.1016/j.jcf.2017.06.008
PubMed: 28711221
Affiliations:
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Electronic address: denis.hadjiliadis@uphs.upenn.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Perelman Hospital, Civic Center Blvd, Philadelphia 19104</wicri:regionArea><placeName><settlement type="city">Philadelphie</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author></analytic><series><title level="j">Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society</title><idno type="eISSN">1873-5010</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lung transplantation (LTx) is an established therapy for patients with end-stage cystic fibrosis (CF). Indeed, CF is the commonest indication for those aged<50years of age needing LTx. CF LTx is associated with a 45% 10year survival - according to the world's largest registry. It is important all otherwise suitable CF patients with severe lung disease have a timely referral for discussion and consideration of the possibility of LTx. LTx discussions must carefully consider colonisation or infection with Burkholderia cenocepacia, Mycobacterium abscessus and Scediosporium - as good LTx outcomes cannot be guaranteed. A bridge to LTx with extra-corporeal lung support is a realistic option, but remains a relative contraindication to LTx. Improvements in LTx matching technology and post-operative management are steadily improving overall long-term outcomes, although chronic allograft rejection remains problematic. Expert multidisciplinary life-long post-LTx care remains the key to success.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28711221</PMID><DateCreated><Year>2017</Year><Month>07</Month><Day>16</Day></DateCreated><DateRevised><Year>2017</Year><Month>09</Month><Day>03</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-5010</ISSN><JournalIssue CitedMedium="Internet"><Volume>16</Volume><Issue>5</Issue><PubDate><Year>2017</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society</Title><ISOAbbreviation>J. Cyst. Fibros.</ISOAbbreviation></Journal><ArticleTitle>The evolution of lung transplantation for cystic fibrosis: A 2017 update.</ArticleTitle><Pagination><MedlinePgn>553-564</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1569-1993(17)30810-X</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jcf.2017.06.008</ELocationID><Abstract><AbstractText>Lung transplantation (LTx) is an established therapy for patients with end-stage cystic fibrosis (CF). Indeed, CF is the commonest indication for those aged<50years of age needing LTx. CF LTx is associated with a 45% 10year survival - according to the world's largest registry. It is important all otherwise suitable CF patients with severe lung disease have a timely referral for discussion and consideration of the possibility of LTx. LTx discussions must carefully consider colonisation or infection with Burkholderia cenocepacia, Mycobacterium abscessus and Scediosporium - as good LTx outcomes cannot be guaranteed. A bridge to LTx with extra-corporeal lung support is a realistic option, but remains a relative contraindication to LTx. Improvements in LTx matching technology and post-operative management are steadily improving overall long-term outcomes, although chronic allograft rejection remains problematic. Expert multidisciplinary life-long post-LTx care remains the key to success.</AbstractText><CopyrightInformation>Copyright © 2017 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Snell</LastName><ForeName>Gregory</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Alfred Hospital, Commercial Rd, Melbourne 3004, Australia. Electronic address: g.snell@alfred.org.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Reed</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Harefield Hospital, Hill End Rd, Harefield UB96JH, United Kingdom. Electronic address: a.reed@rbht.nhs.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stern</LastName><ForeName>Marc</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Hopital Foch, Rue Worth, Suresnes 92151, France. Electronic address: stern.houssaye@wanadoo.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hadjiliadis</LastName><ForeName>Denis</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Perelman Hospital, Civic Center Blvd, Philadelphia 19104, USA. Electronic address: denis.hadjiliadis@uphs.upenn.edu.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>07</Month><Day>12</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>J Cyst Fibros</MedlineTA><NlmUniqueID>101128966</NlmUniqueID><ISSNLinking>1569-1993</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Cystic fibrosis</Keyword><Keyword MajorTopicYN="N">Extracorporeal membrane oxygenation</Keyword><Keyword MajorTopicYN="N">Immunosuppression</Keyword><Keyword MajorTopicYN="N">Lung transplantation</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>11</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>06</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>06</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>7</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>7</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>7</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28711221</ArticleId><ArticleId IdType="pii">S1569-1993(17)30810-X</ArticleId><ArticleId IdType="doi">10.1016/j.jcf.2017.06.008</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>France</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Pennsylvanie</li><li>Victoria (État)</li></region><settlement><li>Melbourne</li><li>Philadelphie</li></settlement></list><tree><country name="Australie"><region name="Victoria (État)"><name sortKey="Snell, Gregory" sort="Snell, Gregory" uniqKey="Snell G" first="Gregory" last="Snell">Gregory Snell</name></region></country><country name="Royaume-Uni"><noRegion><name sortKey="Reed, Anna" sort="Reed, Anna" uniqKey="Reed A" first="Anna" last="Reed">Anna Reed</name></noRegion></country><country name="France"><noRegion><name sortKey="Stern, Marc" sort="Stern, Marc" uniqKey="Stern M" first="Marc" last="Stern">Marc Stern</name></noRegion></country><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Hadjiliadis, Denis" sort="Hadjiliadis, Denis" uniqKey="Hadjiliadis D" first="Denis" last="Hadjiliadis">Denis Hadjiliadis</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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