THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
Identifieur interne : 002197 ( Pmc/Curation ); précédent : 002196; suivant : 002198THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
Auteurs : Stephen Ph Alexander ; Eamonn Kelly ; Neil V. Marrion ; John A. Peters ; Elena Faccenda ; Simon D. Harding ; Adam J. Pawson ; Joanna L. Sharman ; Christopher Southan ; O Peter Buneman ; John A. Cidlowski ; Arthur Christopoulos ; Anthony P. Davenport ; Doriano Fabbro ; Michael Spedding ; Jörg Striessnig ; Jamie A. DaviesSource :
- British Journal of Pharmacology [ 0007-1188 ] ; 2017.
Abstract
The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (
Url:
DOI: 10.1111/bph.13882
PubMed: 29055037
PubMed Central: 5650665
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<front><div type="abstract" xml:lang="en"><p>The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (<ext-link ext-link-type="uri" xlink:href="http://www.guidetopharmacology.org">www.guidetopharmacology.org</ext-link>
), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at <ext-link ext-link-type="uri" xlink:href="http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full">http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full</ext-link>
. In addition to this overview, in which are identified ‘Other protein targets’ which fall outside of the subsequent categorisation, there are eight areas of focus: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.</p>
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<alt-title alt-title-type="right-running-head">THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview</alt-title>
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<contrib-group><contrib id="bph13882-cr-0001" contrib-type="author"><name><surname>Alexander</surname>
<given-names>Stephen PH</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0001"><sup>1</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0002" contrib-type="author"><name><surname>Kelly</surname>
<given-names>Eamonn</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0002"><sup>2</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0003" contrib-type="author"><name><surname>Marrion</surname>
<given-names>Neil V</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0002"><sup>2</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0004" contrib-type="author"><name><surname>Peters</surname>
<given-names>John A</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0003"><sup>3</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0005" contrib-type="author"><name><surname>Faccenda</surname>
<given-names>Elena</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0004"><sup>4</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0006" contrib-type="author"><name><surname>Harding</surname>
<given-names>Simon D</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0004"><sup>4</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0007" contrib-type="author"><name><surname>Pawson</surname>
<given-names>Adam J</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0004"><sup>4</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0008" contrib-type="author"><name><surname>Sharman</surname>
<given-names>Joanna L</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0004"><sup>4</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0009" contrib-type="author"><name><surname>Southan</surname>
<given-names>Christopher</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0004"><sup>4</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0010" contrib-type="author"><name><surname>Buneman</surname>
<given-names>O Peter</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0005"><sup>5</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0011" contrib-type="author"><name><surname>Cidlowski</surname>
<given-names>John A</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0006"><sup>6</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0012" contrib-type="author"><name><surname>Christopoulos</surname>
<given-names>Arthur</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0007"><sup>7</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0013" contrib-type="author"><name><surname>Davenport</surname>
<given-names>Anthony P</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0008"><sup>8</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0014" contrib-type="author"><name><surname>Fabbro</surname>
<given-names>Doriano</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0009"><sup>9</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0015" contrib-type="author"><name><surname>Spedding</surname>
<given-names>Michael</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0010"><sup>10</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0016" contrib-type="author"><name><surname>Striessnig</surname>
<given-names>Jörg</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0011"><sup>11</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0017" contrib-type="author"><name><surname>Davies</surname>
<given-names>Jamie A</given-names>
</name>
<xref ref-type="aff" rid="bph13882-aff-0004"><sup>4</sup>
</xref>
</contrib>
<contrib id="bph13882-cr-0018" contrib-type="author"><collab collab-type="authors">CGTP Collaborators</collab>
</contrib>
</contrib-group>
<contrib-group><contrib id="bph13882-cr-0019" contrib-type="author"><name><surname>Abbracchio</surname>
<given-names>M‐P</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0020" contrib-type="author"><name><surname>Aldrich</surname>
<given-names>R</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0021" contrib-type="author"><name><surname>Al‐Hosaini</surname>
<given-names>K</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0022" contrib-type="author"><name><surname>Arumugam</surname>
<given-names>TV</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0023" contrib-type="author"><name><surname>Attali</surname>
<given-names>B</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0024" contrib-type="author"><name><surname>Bäck</surname>
<given-names>M</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0025" contrib-type="author"><name><surname>Barnes</surname>
<given-names>NM</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0026" contrib-type="author"><name><surname>Bathgate</surname>
<given-names>R</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0027" contrib-type="author"><name><surname>Beart</surname>
<given-names>PM</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0028" contrib-type="author"><name><surname>Becirovic</surname>
<given-names>E</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0029" contrib-type="author"><name><surname>Bettler</surname>
<given-names>B</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0030" contrib-type="author"><name><surname>Biel</surname>
<given-names>M</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0031" contrib-type="author"><name><surname>Birdsall</surname>
<given-names>NJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0032" contrib-type="author"><name><surname>Blaho</surname>
<given-names>V</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0033" contrib-type="author"><name><surname>Boison</surname>
<given-names>D</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0034" contrib-type="author"><name><surname>Bräuner‐osborne</surname>
<given-names>H</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0035" contrib-type="author"><name><surname>Bröer</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0036" contrib-type="author"><name><surname>Bryant</surname>
<given-names>C</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0037" contrib-type="author"><name><surname>Burnstock</surname>
<given-names>G</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0038" contrib-type="author"><name><surname>Calo</surname>
<given-names>G</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0039" contrib-type="author"><name><surname>Catterall</surname>
<given-names>WA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0040" contrib-type="author"><name><surname>Ceruti</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0041" contrib-type="author"><name><surname>Chan</surname>
<given-names>SL</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0042" contrib-type="author"><name><surname>Chandy</surname>
<given-names>KG</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0043" contrib-type="author"><name><surname>Chazot</surname>
<given-names>P</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0044" contrib-type="author"><name><surname>Chiang</surname>
<given-names>N</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0045" contrib-type="author"><name><surname>Chun</surname>
<given-names>JJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0046" contrib-type="author"><name><surname>Chung</surname>
<given-names>J‐J</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0047" contrib-type="author"><name><surname>Clapham</surname>
<given-names>DE</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0048" contrib-type="author"><name><surname>Clapp</surname>
<given-names>L</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0049" contrib-type="author"><name><surname>Connor</surname>
<given-names>MA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0050" contrib-type="author"><name><surname>Cox</surname>
<given-names>HM</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0051" contrib-type="author"><name><surname>Davies</surname>
<given-names>P</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0052" contrib-type="author"><name><surname>Dawson</surname>
<given-names>PA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0053" contrib-type="author"><name><surname>Decaen</surname>
<given-names>P</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0054" contrib-type="author"><name><surname>Dent</surname>
<given-names>G</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0055" contrib-type="author"><name><surname>Doherty</surname>
<given-names>P</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0056" contrib-type="author"><name><surname>Douglas</surname>
<given-names>SD</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0057" contrib-type="author"><name><surname>Dubocovich</surname>
<given-names>ML</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0058" contrib-type="author"><name><surname>Fong</surname>
<given-names>TM</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0059" contrib-type="author"><name><surname>Fowler</surname>
<given-names>CJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0060" contrib-type="author"><name><surname>Frantz</surname>
<given-names>A</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0061" contrib-type="author"><name><surname>Fuller</surname>
<given-names>P</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0062" contrib-type="author"><name><surname>Fumagalli</surname>
<given-names>M</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0063" contrib-type="author"><name><surname>Futerman</surname>
<given-names>AH</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0064" contrib-type="author"><name><surname>Gainetdinov</surname>
<given-names>RR</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0065" contrib-type="author"><name><surname>Gershengorn</surname>
<given-names>MA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0066" contrib-type="author"><name><surname>Goldin</surname>
<given-names>A</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0067" contrib-type="author"><name><surname>Goldstein</surname>
<given-names>SAN</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0068" contrib-type="author"><name><surname>Goudet</surname>
<given-names>C</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0069" contrib-type="author"><name><surname>Gregory</surname>
<given-names>K</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0070" contrib-type="author"><name><surname>Grissmer</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0071" contrib-type="author"><name><surname>Gundlach</surname>
<given-names>AL</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0072" contrib-type="author"><name><surname>Hagenbuch</surname>
<given-names>B</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0073" contrib-type="author"><name><surname>Hamann</surname>
<given-names>J</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0074" contrib-type="author"><name><surname>Hammond</surname>
<given-names>JR</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0075" contrib-type="author"><name><surname>Hancox</surname>
<given-names>JC</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0076" contrib-type="author"><name><surname>Hanson</surname>
<given-names>J</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0077" contrib-type="author"><name><surname>Hanukoglu</surname>
<given-names>I</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0078" contrib-type="author"><name><surname>Hay</surname>
<given-names>DL</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0079" contrib-type="author"><name><surname>Hobbs</surname>
<given-names>AJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0080" contrib-type="author"><name><surname>Hollenberg</surname>
<given-names>AN</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0081" contrib-type="author"><name><surname>Holliday</surname>
<given-names>ND</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0082" contrib-type="author"><name><surname>Hoyer</surname>
<given-names>D</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0083" contrib-type="author"><name><surname>Ijzerman</surname>
<given-names>AP</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0084" contrib-type="author"><name><surname>Inui</surname>
<given-names>KI</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0085" contrib-type="author"><name><surname>Irving</surname>
<given-names>AJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0086" contrib-type="author"><name><surname>Ishii</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0087" contrib-type="author"><name><surname>Jacobson</surname>
<given-names>KA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0088" contrib-type="author"><name><surname>Jan</surname>
<given-names>LY</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0089" contrib-type="author"><name><surname>Jarvis</surname>
<given-names>MF</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0090" contrib-type="author"><name><surname>Jensen</surname>
<given-names>R</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0091" contrib-type="author"><name><surname>Jockers</surname>
<given-names>R</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0092" contrib-type="author"><name><surname>Kaczmarek</surname>
<given-names>LK</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0093" contrib-type="author"><name><surname>Kanai</surname>
<given-names>Y</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0094" contrib-type="author"><name><surname>Karnik</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0095" contrib-type="author"><name><surname>Kellenberger</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0096" contrib-type="author"><name><surname>Kemp</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0097" contrib-type="author"><name><surname>Kennedy</surname>
<given-names>C</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0098" contrib-type="author"><name><surname>Kerr</surname>
<given-names>ID</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0099" contrib-type="author"><name><surname>Kihara</surname>
<given-names>Y</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0100" contrib-type="author"><name><surname>Kukkonen</surname>
<given-names>J</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0101" contrib-type="author"><name><surname>Larhammar</surname>
<given-names>D</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0102" contrib-type="author"><name><surname>Leach</surname>
<given-names>K</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0103" contrib-type="author"><name><surname>Lecca</surname>
<given-names>D</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0104" contrib-type="author"><name><surname>Leeman</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0105" contrib-type="author"><name><surname>Leprince</surname>
<given-names>J</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0106" contrib-type="author"><name><surname>Lolait</surname>
<given-names>SJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0107" contrib-type="author"><name><surname>Macewan</surname>
<given-names>D</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0108" contrib-type="author"><name><surname>Maguire</surname>
<given-names>JJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0109" contrib-type="author"><name><surname>Marshall</surname>
<given-names>F</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0110" contrib-type="author"><name><surname>Mazella</surname>
<given-names>J</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0111" contrib-type="author"><name><surname>Mcardle</surname>
<given-names>CA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0112" contrib-type="author"><name><surname>Michel</surname>
<given-names>MC</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0113" contrib-type="author"><name><surname>Miller</surname>
<given-names>LJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0114" contrib-type="author"><name><surname>Mitolo</surname>
<given-names>V</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0115" contrib-type="author"><name><surname>Mizuno</surname>
<given-names>H</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<given-names>PN</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<given-names>B</given-names>
</name>
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<given-names>PM</given-names>
</name>
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<given-names>J‐L</given-names>
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<given-names>J</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<given-names>CG</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0122" contrib-type="author"><name><surname>Norel</surname>
<given-names>X</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0123" contrib-type="author"><name><surname>Offermanns</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<given-names>LG</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0125" contrib-type="author"><name><surname>Panaro</surname>
<given-names>MA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
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<contrib id="bph13882-cr-0126" contrib-type="author"><name><surname>Papapetropoulos</surname>
<given-names>A</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0127" contrib-type="author"><name><surname>Perez‐reyes</surname>
<given-names>E</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0128" contrib-type="author"><name><surname>Pertwee</surname>
<given-names>RG</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0129" contrib-type="author"><name><surname>Pintor</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0130" contrib-type="author"><name><surname>Pisegna</surname>
<given-names>JR</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0131" contrib-type="author"><name><surname>Plant</surname>
<given-names>LD</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0132" contrib-type="author"><name><surname>Poyner</surname>
<given-names>DR</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0133" contrib-type="author"><name><surname>Prossnitz</surname>
<given-names>ER</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0134" contrib-type="author"><name><surname>Pyne</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0135" contrib-type="author"><name><surname>Ramachandran</surname>
<given-names>R</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0136" contrib-type="author"><name><surname>Ren</surname>
<given-names>D</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0137" contrib-type="author"><name><surname>Rondard</surname>
<given-names>P</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0138" contrib-type="author"><name><surname>Ruzza</surname>
<given-names>C</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0139" contrib-type="author"><name><surname>Sackin</surname>
<given-names>H</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0140" contrib-type="author"><name><surname>Sanger</surname>
<given-names>G</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0141" contrib-type="author"><name><surname>Sanguinetti</surname>
<given-names>MC</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0142" contrib-type="author"><name><surname>Schild</surname>
<given-names>L</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0143" contrib-type="author"><name><surname>Schiöth</surname>
<given-names>H</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0144" contrib-type="author"><name><surname>Schulte</surname>
<given-names>G</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0145" contrib-type="author"><name><surname>Schulz</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0146" contrib-type="author"><name><surname>Segaloff</surname>
<given-names>DL</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0147" contrib-type="author"><name><surname>Serhan</surname>
<given-names>CN</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0148" contrib-type="author"><name><surname>Singh</surname>
<given-names>KD</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0149" contrib-type="author"><name><surname>Slesinger</surname>
<given-names>PA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0150" contrib-type="author"><name><surname>Snutch</surname>
<given-names>TP</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0151" contrib-type="author"><name><surname>Sobey</surname>
<given-names>CG</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0152" contrib-type="author"><name><surname>Stewart</surname>
<given-names>G</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0153" contrib-type="author"><name><surname>Stoddart</surname>
<given-names>LA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0154" contrib-type="author"><name><surname>Summers</surname>
<given-names>RJ</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0155" contrib-type="author"><name><surname>Szabo</surname>
<given-names>C</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0156" contrib-type="author"><name><surname>Thwaites</surname>
<given-names>D</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0157" contrib-type="author"><name><surname>Toll</surname>
<given-names>L</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0158" contrib-type="author"><name><surname>Trimmer</surname>
<given-names>JS</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0159" contrib-type="author"><name><surname>Tucker</surname>
<given-names>S</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0160" contrib-type="author"><name><surname>Vaudry</surname>
<given-names>H</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0161" contrib-type="author"><name><surname>Verri</surname>
<given-names>T</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0162" contrib-type="author"><name><surname>Vilargada</surname>
<given-names>J‐P</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0163" contrib-type="author"><name><surname>Waldman</surname>
<given-names>SA</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0164" contrib-type="author"><name><surname>Ward</surname>
<given-names>DT</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0165" contrib-type="author"><name><surname>Waxman</surname>
<given-names>SG</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0166" contrib-type="author"><name><surname>Wei</surname>
<given-names>AD</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0167" contrib-type="author"><name><surname>Willars</surname>
<given-names>GB</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0168" contrib-type="author"><name><surname>Wong</surname>
<given-names>SS</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0169" contrib-type="author"><name><surname>Woodruff</surname>
<given-names>TM</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0170" contrib-type="author"><name><surname>Wulff</surname>
<given-names>H</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0171" contrib-type="author"><name><surname>Ye</surname>
<given-names>RD</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0172" contrib-type="author"><name><surname>Yung</surname>
<given-names>Y</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
<contrib id="bph13882-cr-0173" contrib-type="author"><name><surname>Zajac</surname>
<given-names>J‐M</given-names>
</name>
<xref ref-type="contrib" rid="bph13882-cr-0018"></xref>
</contrib>
</contrib-group>
<aff id="bph13882-aff-0001"><label><sup>1</sup>
</label>
<named-content content-type="organisation-division">School of Life Sciences</named-content>
<institution>University of Nottingham Medical School</institution>
<named-content content-type="city">Nottingham</named-content>
<named-content content-type="post-code">NG7 2UH</named-content>
<country country="GB">UK</country>
</aff>
<aff id="bph13882-aff-0002"><label><sup>2</sup>
</label>
<named-content content-type="organisation-division">School of Physiology, Pharmacology and Neuroscience</named-content>
<institution>University of Bristol</institution>
<named-content content-type="city">Bristol</named-content>
<named-content content-type="post-code">BS8 1TD</named-content>
<country country="GB">UK</country>
</aff>
<aff id="bph13882-aff-0003"><label><sup>3</sup>
</label>
<named-content content-type="organisation-division">Neuroscience Division, Medical Education Institute</named-content>
<institution>Ninewells Hospital and Medical School, University of Dundee</institution>
<named-content content-type="city">Dundee</named-content>
<named-content content-type="post-code">DD1 9SY</named-content>
<country country="GB">UK</country>
</aff>
<aff id="bph13882-aff-0004"><label><sup>4</sup>
</label>
<named-content content-type="organisation-division">Centre for Integrative Physiology</named-content>
<institution>University of Edinburgh</institution>
<named-content content-type="city">Edinburgh</named-content>
<named-content content-type="post-code">EH8 9XD</named-content>
<country country="GB">UK</country>
</aff>
<aff id="bph13882-aff-0005"><label><sup>5</sup>
</label>
<named-content content-type="organisation-division">Laboratory for Foundations of Computer Science, School of Informatics</named-content>
<institution>University of Edinburgh</institution>
<named-content content-type="city">Edinburgh</named-content>
<named-content content-type="post-code">EH8 9LE</named-content>
<country country="GB">United Kingdom</country>
</aff>
<aff id="bph13882-aff-0006"><label><sup>6</sup>
</label>
<named-content content-type="organisation-division">National Institute of Environmental Health Sciences, National Institutes of Health</named-content>
<institution>Department of Health and Human Services</institution>
<named-content content-type="city">Research Triangle Park</named-content>
<named-content content-type="post-code">NC 27709</named-content>
<country country="US">USA</country>
</aff>
<aff id="bph13882-aff-0007"><label><sup>7</sup>
</label>
<named-content content-type="organisation-division">Monash Institute of Pharmaceutical Sciences and Department of Pharmacology</named-content>
<institution>Monash University</institution>
<named-content content-type="city">Parkville</named-content>
<named-content content-type="post-code">Victoria 3052</named-content>
<country country="AU">Australia</country>
</aff>
<aff id="bph13882-aff-0008"><label><sup>8</sup>
</label>
<named-content content-type="organisation-division">Clinical Pharmacology Unit</named-content>
<institution>University of Cambridge</institution>
<named-content content-type="city">Cambridge</named-content>
<named-content content-type="post-code">CB2 0QQ</named-content>
<country country="GB">UK</country>
</aff>
<aff id="bph13882-aff-0009"><label><sup>9</sup>
</label>
<institution>PIQUR Therapeutics</institution>
<named-content content-type="city">Basel</named-content>
<named-content content-type="post-code">4057</named-content>
<country country="CH">Switzerland</country>
</aff>
<aff id="bph13882-aff-0010"><label><sup>10</sup>
</label>
<institution>Spedding Research Solutions SARL</institution>
<named-content content-type="city">Le Vésinet</named-content>
<named-content content-type="post-code">78110</named-content>
<country country="FR">France</country>
</aff>
<aff id="bph13882-aff-0011"><label><sup>11</sup>
</label>
<named-content content-type="organisation-division">Pharmacology and Toxicology</named-content>
<institution>Institute of Pharmacy</institution>
<named-content content-type="city">University of Innsbruck</named-content>
<named-content content-type="post-code">A‐6020 Innsbruck</named-content>
<country country="AT">Austria</country>
</aff>
<pub-date pub-type="epub"><day>21</day>
<month>10</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="ppub"><month>12</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>21</day>
<month>10</month>
<year>2017</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on the . </pmc-comment>
<volume>174</volume>
<issue>Suppl Suppl 1</issue>
<issue-id pub-id-type="doi">10.1111/bph.v174.S1</issue-id>
<fpage>S1</fpage>
<lpage>S16</lpage>
<permissions><pmc-comment> © 2017 The British Pharmacological Society </pmc-comment>
<copyright-statement content-type="article-copyright">© 2017 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.</copyright-statement>
<license license-type="creativeCommonsBy"><license-p>This is an open access article under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution</ext-link>
License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<self-uri content-type="pdf" xlink:type="simple" xlink:href="file:BPH-174-S1.pdf"></self-uri>
<abstract id="bph13882-abs-0001"><p>The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (<ext-link ext-link-type="uri" xlink:href="http://www.guidetopharmacology.org">www.guidetopharmacology.org</ext-link>
), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at <ext-link ext-link-type="uri" xlink:href="http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full">http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full</ext-link>
. In addition to this overview, in which are identified ‘Other protein targets’ which fall outside of the subsequent categorisation, there are eight areas of focus: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.</p>
</abstract>
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<notes><p content-type="self-citation"><mixed-citation publication-type="journal" id="bph13882-cit-0000"><string-name><surname>Alexander</surname>
, <given-names>S. P. H.</given-names>
</string-name>
, <string-name><surname>Kelly</surname>
, <given-names>E.</given-names>
</string-name>
, <string-name><surname>Marrion</surname>
, <given-names>N. V.</given-names>
</string-name>
, <string-name><surname>Peters</surname>
, <given-names>J. A.</given-names>
</string-name>
, <string-name><surname>Faccenda</surname>
, <given-names>E.</given-names>
</string-name>
, <string-name><surname>Harding</surname>
, <given-names>S. D.</given-names>
</string-name>
, <string-name><surname>Pawson</surname>
, <given-names>A. J.</given-names>
</string-name>
, <string-name><surname>Sharman</surname>
, <given-names>J. L.</given-names>
</string-name>
, <string-name><surname>Southan</surname>
, <given-names>C.</given-names>
</string-name>
, <string-name><surname>Buneman</surname>
, <given-names>O. P.</given-names>
</string-name>
, <string-name><surname>Cidlowski</surname>
, <given-names>J. A.</given-names>
</string-name>
, <string-name><surname>Christopoulos</surname>
, <given-names>A.</given-names>
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, <string-name><surname>Davenport</surname>
, <given-names>A. P.</given-names>
</string-name>
, <string-name><surname>Fabbro</surname>
, <given-names>D.</given-names>
</string-name>
, <string-name><surname>Spedding</surname>
, <given-names>M.</given-names>
</string-name>
, <string-name><surname>Striessnig</surname>
, <given-names>J.</given-names>
</string-name>
, <string-name><surname>Davies</surname>
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, and <collab collab-type="authors">CGTP Collaborators</collab>
(<year>2017</year>
) <article-title>THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview</article-title>
. <source>British Journal of Pharmacology</source>
, <volume>174</volume>
: <fpage>S1</fpage>
–<lpage>S16</lpage>
. doi: <ext-link ext-link-type="doi" xlink:href="10.1111/bph.13882">10.1111/bph.13882</ext-link>
.</mixed-citation>
</p>
</notes>
</front>
</pmc>
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